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"compartment_display": "none" }, { "id": "P04911", "map_id": "P04911", "name": "HTA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR225W", "map_id": "YDR225W", "name": "HTA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P61830", "map_id": "P61830", "name": "HHT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR010W", "map_id": "YBR010W", "name": "HHT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763301", "map_id": "none", "name": "Loss of Rrn3 from RNA Polymerase I promoter escape complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10763295", "map_id": "none", "name": "RNA Polymerase I Transcription Initiation complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P36070", "map_id": "P36070", "name": "RRN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL125W", "map_id": "YKL125W", "name": "RRN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10763212", "map_id": "P36070", "name": "RRN3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10763216", "map_id": "none", "name": "Binding of RRN3 to RNA Polymerase I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10763207", "map_id": "none", "name": "RNA Polymerase I Holoenzyme", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10763214", "map_id": "none", "name": "Active RNA Polymerase I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10760927", "map_id": "none", "name": "RFC binding displaces Pol Alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760830", "map_id": "none", "name": "RNA primer-DNA primer:origin duplex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10760923", "map_id": "none", "name": "RFC Heteropentamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P40348", "map_id": "P40348", "name": "RFC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR068W", "map_id": "YJR068W", "name": "RFC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38630", "map_id": "P38630", "name": "RFC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR217W", "map_id": "YOR217W", "name": "RFC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40339", "map_id": "P40339", "name": "RFC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL094C", "map_id": "YOL094C", "name": "RFC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38251", "map_id": "P38251", "name": "RFC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR087W", "map_id": "YBR087W", "name": "RFC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38629", "map_id": "P38629", "name": "RFC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL290W", "map_id": "YNL290W", "name": "RFC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10760925", "map_id": "none", "name": "RFC Heteropentamer:RNA primer-DNA primer:origin duplex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10760938", "map_id": "none", "name": "Loading of PCNA - Sliding Clamp Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_29358", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760934", "map_id": "none", "name": "PCNA homotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_113582", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760936", "map_id": "none", "name": "RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10760942", "map_id": "none", "name": "RFC dissociates after sliding clamp formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760940", "map_id": "none", "name": "RNA primer-DNA primer:origin duplex:PCNA ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10773145", "map_id": "none", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[5]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_426925", "map_id": "CHEBI:16110", "name": "PC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_29356", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1524028", "map_id": "CHEBI:17504", "name": "1-acyl LPC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1524021", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10773142", "map_id": "none", "name": "PLA2(5)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P39105", "map_id": "P39105", "name": "phospho-PLB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR008C", "map_id": "YMR008C", "name": "phospho-PLB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08108", "map_id": "Q08108", "name": "phospho-PLB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL011W", "map_id": "YOL011W", "name": "phospho-PLB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53541", "map_id": "P53541", "name": "phospho-SPO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL012W", "map_id": "YNL012W", "name": "phospho-SPO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_74016", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "Q03674", "map_id": "Q03674", "name": "phospho-PLB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR006C", "map_id": "YMR006C", "name": "phospho-PLB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773130", "map_id": "none", "name": "PC is hydrolyzed to 2-acyl LPC by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_975614", "map_id": "CHEBI:16728", "name": "2-acyl LPC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10772954", "map_id": "none", "name": "Homologues of PLA2G4C", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10772925", "map_id": "none", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500578", "map_id": "CHEBI:17984", "name": "acyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76194", "map_id": "CHEBI:57287", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772920", "map_id": "Q08548", "name": "ALE1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YOR175C", "map_id": "YOR175C", "name": "ALE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773122", "map_id": "none", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10772968", "map_id": "none", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10773151", "map_id": "none", "name": "PC is hydrolysed to 2-acyl LPC by PLA2[7]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10773024", "map_id": "none", "name": "PLA2(8)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10774233", "map_id": "none", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113671", "map_id": "CHEBI:16810", "name": "2OG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10774226", "map_id": "none", "name": "PHF8:Nucleosome with H3K4me2/3:H4K20me1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_111793", "map_id": "CHEBI:29033", "name": "Fe2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_113685", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_159942", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10774230", "map_id": "none", "name": "PHF8:Nucleosome with H3K4me2/3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_159939", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_29478", "map_id": "CHEBI:16842", "name": "CH2O", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10777844", "map_id": "none", "name": "PKC-delta translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10777274", "map_id": "P24583", "name": "phospho-PKC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YBL105C", "map_id": "YBL105C", "name": "PKC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_112275", "map_id": "CHEBI:18035", "name": "DAGs", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10777842", "map_id": "none", "name": "DAGs:p-T507,S645,S664-PRKCD", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P24583", "map_id": "P24583", "name": "PKC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10774717", "map_id": "none", "name": "Translocation of CaN:CaM:NFAT to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10774691", "map_id": "none", "name": "NFAT:CaN:CaM", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P06787", "map_id": "P06787", "name": "CMD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR109C", "map_id": "YBR109C", "name": "CMD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_158417", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "P14747", "map_id": "P14747", "name": "CMP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML057W", "map_id": "YML057W", "name": "CMP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25296", "map_id": "P25296", "name": "CNB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL190W", "map_id": "YKL190W", "name": "CNB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:29034", "map_id": "CHEBI:29034", "name": "CHEBI:29034", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P23287", "map_id": "P23287", "name": "CNA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR433C", "map_id": "YLR433C", "name": "CNA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10774715", "map_id": "none", "name": "NFAT:CaN:CaM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10777848", "map_id": "none", "name": "PKC-delta is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10777846", "map_id": "none", "name": "DAGs:active p-T507,S645,S664-PRKCD", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10774719", "map_id": "none", "name": "Activation of Calcineurin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767628", "map_id": "none", "name": "CALM1:4xCa2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10773995", "map_id": "none", "name": "Calcineurin (CaN)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10774687", "map_id": "none", "name": "Calcineurin:Calmodulin (CaN:CaM)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10777840", "map_id": "none", "name": "Activation of NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769138", "map_id": "P25390", "name": "SSK22", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YCR073C", "map_id": "YCR073C", "name": "phospho-SSK22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10774165", "map_id": "none", "name": "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2161185", "map_id": "LigandDisplayForward?ligandId=11152", "name": "abacavir", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29360", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_70106", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_73473", "map_id": "CHEBI:57945", "name": "NADH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2162081", "map_id": "CHEBI:64192", "name": "abacavir 5'-carboxylic acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10762111", "map_id": "none", "name": "ADH1A:2Zn2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32771", "map_id": "P32771", "name": "SFA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL168W", "map_id": "YDL168W", "name": "SFA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10760457", "map_id": "none", "name": "Orc1 is phosphorylated by cyclin A/CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760396", "map_id": "none", "name": "pre-replicative complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P24279", "map_id": "P24279", "name": "MCM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MCM3", "map_id": "MCM3", "name": "MCM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P29469", "map_id": "P29469", "name": "MCM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MCM2", "map_id": "MCM2", "name": "MCM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38132", "map_id": "P38132", "name": "MCM7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MCM7", "map_id": "MCM7", "name": "MCM7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32833", "map_id": "P32833", "name": "ORC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ORC2", "map_id": "ORC2", "name": "ORC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P54791", "map_id": "P54791", "name": "ORC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ORC4", "map_id": "ORC4", "name": "ORC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P30665", "map_id": "P30665", "name": "MCM4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MCM4", "map_id": "MCM4", "name": "MCM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P54784", "map_id": "P54784", "name": "phospho-ORC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "phospho-ORC1", "map_id": "phospho-ORC1", "name": "phospho-ORC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P09119", "map_id": "P09119", "name": "CDC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CDC6", "map_id": "CDC6", "name": "CDC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53091", "map_id": "P53091", "name": "MCM6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MCM6", "map_id": "MCM6", "name": "MCM6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P50874", "map_id": "P50874", "name": "ORC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ORC5", "map_id": "ORC5", "name": "ORC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P29496", "map_id": "P29496", "name": "MCM5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MCM5", "map_id": "MCM5", "name": "MCM5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P54790", "map_id": "P54790", "name": "ORC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ORC3", "map_id": "ORC3", "name": "ORC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10760408", "map_id": "none", "name": "pre-replicative complex (Orc1-minus)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10760404", "map_id": "P54784", "name": "phospho-ORC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760454", "map_id": "none", "name": "CCNA:p-T160-CDK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P13365", "map_id": "P13365", "name": "CLN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL040C", "map_id": "YAL040C", "name": "CLN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P20438", "map_id": "P20438", "name": "CLN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL256C", "map_id": "YPL256C", "name": "CLN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32943", "map_id": "P32943", "name": "CLB6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR109C", "map_id": "YGR109C", "name": "CLB6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P24868", "map_id": "P24868", "name": "CLB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR108W", "map_id": "YGR108W", "name": "CLB1", "type": 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"inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR120C", "map_id": "YPR120C", "name": "CLB5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P20437", "map_id": "P20437", "name": "CLN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR199W", "map_id": "YMR199W", "name": "CLN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10760888", "map_id": "none", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10760896", "map_id": "none", "name": "Mcm4,6,7 trimer forms and associates with the replication fork", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760363", "map_id": "none", "name": "MCM2-7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10760359", "map_id": "P29496", "name": "MCM5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760355", "map_id": "P24279", "name": "MCM3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760349", "map_id": "none", "name": "MCM4:MCM6:MCM7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10760335", "map_id": "P29469", "name": "MCM2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10760884", "map_id": "none", "name": "Cdc6 protein is phosphorylated by CDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760214", "map_id": "P09119", "name": "CDC6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760881", "map_id": "none", "name": "CCNA:p-T160-CDK2,CCNE:p-T160-CDK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10760894", "map_id": "none", "name": "Ubiquitinated Cdc6 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10760892", "map_id": "none", "name": "ubiquitinated Cdc6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10765258", "map_id": "none", "name": "Activation of conventional Protein Kinase C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_33625", "map_id": "CHEBI:18303", "name": "PS", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10765240", "map_id": "P24583", "name": "PKC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_114519", "map_id": "CHEBI:17815", "name": "DAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10765256", "map_id": "none", "name": "Activated conventional protein kinase C", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_6797635", "map_id": "CHEBI:17815", "name": "1,2-DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10769689", "map_id": "none", "name": "2-AG hydrolysis to arachidonate by MAGL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_426030", "map_id": "CHEBI:52392", "name": "2AG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_76116", "map_id": "CHEBI:17754", "name": "Glycerol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_422506", "map_id": "CHEBI:15843", "name": "AA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10769686", "map_id": "P28321", "name": "YJU3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YKL094W", "map_id": "YKL094W", "name": "YJU3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765269", "map_id": "none", "name": "Phosphorylation of Platelet Sec-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10765263", "map_id": "P30619", "name": "SEC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YDR164C", "map_id": "YDR164C", "name": "phospho-SEC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113592", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29370", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10765266", "map_id": "P30619", "name": "phospho-SEC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10771032", "map_id": "none", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10771010", "map_id": "none", "name": "Platelet releasate cytosolic proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P60010", "map_id": "P60010", "name": "ACT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFL039C", "map_id": "YFL039C", "name": "ACT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P09734", "map_id": "P09734", "name": "TUB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML124C", "map_id": "YML124C", "name": "TUB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12311", "map_id": "Q12311", "name": "NTO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR031W", "map_id": "YPR031W", "name": "NTO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P46680", "map_id": "P46680", "name": "AIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR092C", "map_id": "YMR092C", "name": "AIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P30619", "map_id": "P30619", "name": "phospho-SEC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00445", "map_id": "P00445", "name": "SOD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SOD1", "map_id": "SOD1", "name": "SOD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P09733", "map_id": "P09733", "name": "TUB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML085C", "map_id": "YML085C", "name": "TUB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10771030", "map_id": "none", "name": "Platelet releasate cytosolic proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10769954", "map_id": "none", "name": "P2Y purinoceptor 1 activates MAP kinase p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769952", "map_id": "P32485", "name": "HOG1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YLR113W", "map_id": "YLR113W", "name": "phospho-HOG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10766455", "map_id": "P32485", "name": "phospho-HOG1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10764870", "map_id": "none", "name": "G protein alpha:GTP complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_29438", "map_id": "CHEBI:37565", "name": "GTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "P10823", "map_id": "P10823", "name": "GPA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER020W", "map_id": "YER020W", "name": "GPA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768515", "map_id": "none", "name": "Activation of Rap1 by cytosolic GEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768483", "map_id": "none", "name": "RAP1:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_29420", "map_id": "CHEBI:58189", "name": "GDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "P13856", "map_id": "P13856", "name": "RSR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR152C", "map_id": "YGR152C", "name": "RSR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768481", "map_id": "none", "name": "RAP1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10768512", "map_id": "none", "name": "CalDAG-GEFs:DAG:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P04821", "map_id": "P04821", "name": "CDC25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR310C", "map_id": "YLR310C", "name": "CDC25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P07866", "map_id": "P07866", "name": "LTE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL024C", "map_id": "YAL024C", "name": "LTE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25300", "map_id": "P25300", "name": "BUD5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCR038C", "map_id": "YCR038C", "name": "BUD5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765291", "map_id": "none", "name": "Phosphorylation of Syntaxin-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10765281", "map_id": "none", "name": "Homologues of STX4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32867", "map_id": "P32867", "name": "SSO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL232W", "map_id": "YPL232W", "name": "SSO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39926", "map_id": "P39926", "name": "SSO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR183C", "map_id": "YMR183C", "name": "SSO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765289", "map_id": "none", "name": "Homologues of p-STX4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10770963", "map_id": "none", "name": "Exocytosis of platelet dense granule content", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10770957", "map_id": "none", "name": "Platelet dense granule content", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_114524", "compartment_display": "platelet dense granule lumen", "complex": "true" }, { "id": "species_29372", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111294", "map_id": "CHEBI:33019", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:15996", "map_id": "CHEBI:15996", "name": "CHEBI:15996", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_111349", "map_id": "CHEBI:17552", "name": "GDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "P06101", "map_id": "P06101", "name": "CDC37", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR168W", "map_id": "YDR168W", "name": "CDC37", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_109496", "map_id": "CHEBI:18420", "name": "Mg2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_209914", "map_id": "CHEBI:28790", "name": "5HT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10770961", "map_id": "none", "name": "Platelet dense granule content", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10769661", "map_id": "none", "name": "Activation of Protein Kinase C novel isoforms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767110", "map_id": "P24583", "name": "PKC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10769659", "map_id": "none", "name": "Protein kinase C, novel isoforms:DAG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10770980", "map_id": "none", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10770972", "map_id": "none", "name": "Platelet alpha granule membrane components that are released on degranulation", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_114510", "compartment_display": "platelet alpha granule membrane", "complex": "true" }, { "id": "P38626", "map_id": "P38626", "name": "CBR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL043C", "map_id": "YIL043C", "name": "CBR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53858", "map_id": "P53858", "name": "BNI4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL233W", "map_id": "YNL233W", "name": "BNI4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10770978", "map_id": "none", "name": "Platelet alpha granule membrane components that are released on degranulation", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10774272", "map_id": "none", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767662", "map_id": "Q12236", "name": "PKH2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YOL100W", "map_id": "YOL100W", "name": "PKH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_179838", "map_id": "CHEBI:16618", "name": "PI(3,4,5)P3", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10764515", "map_id": "none", "name": "PDPK1:PIP3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q12236", "map_id": "Q12236", "name": "PKH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769967", "map_id": "none", "name": "Phosphorylation of cPLA2 by MAPK p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769964", "map_id": "none", "name": "Homologues of PLA2G4A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10764905", "map_id": "none", "name": "Homologues of p-S505,S727-PLA2G4A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10770950", "map_id": "none", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10770940", "map_id": "none", "name": "Platelet alpha granule contents", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_114506", "compartment_display": "platelet alpha granule lumen", "complex": "true" }, { "id": "Q05541", "map_id": "Q05541", "name": "NSE3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR288W", "map_id": "YDR288W", "name": "NSE3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04338", "map_id": "Q04338", "name": "VTI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR197C", "map_id": "YMR197C", "name": "VTI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38219", "map_id": "P38219", "name": "OLA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR025C", "map_id": "YBR025C", "name": "OLA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10770948", "map_id": "none", "name": "Platelet alpha granule contents", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10781550", "map_id": "none", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5694509", "map_id": "CHEBI:75571", "name": "3AG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10781547", "map_id": "P38139", "name": "LDH1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YBR204C", "map_id": "YBR204C", "name": "LDH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769989", "map_id": "none", "name": "ABCC4 accumulation of dense granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_114584", "compartment_display": "platelet dense granule membrane" }, { "id": "species_114565", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_114524", "compartment_display": "platelet dense granule lumen", "complex": "false" }, { "id": "species_10769986", "map_id": "P12866", "name": "STE6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_114584", "compartment_display": "platelet dense granule membrane", "complex": "false" }, { "id": "YKL209C", "map_id": "YKL209C", "name": "STE6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770278", "map_id": "none", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770270", "map_id": "none", "name": "CaMKK:CALM1:4xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P43637", "map_id": "P43637", "name": "phospho-TOS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL179C", "map_id": "YGL179C", "name": "phospho-TOS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10770275", "map_id": "none", "name": "p-CaMKK:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10789297", "map_id": "none", "name": "GMPS dimer transforms 6TXMP to 6TGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29472", "map_id": "CHEBI:58359", "name": "L-Gln", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9748959", "map_id": "CHEBI:180685", "name": "6TXMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9748970", "map_id": "CHEBI:180686", "name": "6TGMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29404", "map_id": "CHEBI:29985", "name": "L-Glu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76577", "map_id": "CHEBI:456215", "name": "AMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10789294", "map_id": "none", "name": "GMPS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38625", "map_id": "P38625", "name": "GUA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR217W", "map_id": "YMR217W", "name": "GUA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789292", "map_id": "none", "name": "GUK1 phosphorylates 6TGMP to 6TGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9748960", "map_id": "CHEBI:180687", "name": "6TGDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10763306", "map_id": "P15454", "name": "GUK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YDR454C", "map_id": "YDR454C", "name": "GUK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766344", "map_id": "none", "name": "UGTs transfer GlcA from UDP-GlcA to O-centre substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_174384", "map_id": "CHEBI:58052", "name": "UDP-GlcA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_174911", "map_id": "none", "name": "O-centre functional group substrate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "CHEBI:16580", "map_id": "CHEBI:16580", "name": "CHEBI:16580", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:34665", "map_id": "CHEBI:34665", "name": "CHEBI:34665", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:15882", "map_id": "CHEBI:15882", "name": "CHEBI:15882", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9749790", "map_id": "CHEBI:30762", "name": "ST (hepatocyte)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "CHEBI:46195", "map_id": "CHEBI:46195", "name": "CHEBI:46195", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_158602", "map_id": "CHEBI:17659", "name": "UDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_174914", "map_id": "none", "name": "O-glucuronide", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:32649", "map_id": "CHEBI:32649", "name": "CHEBI:32649", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_158604", "map_id": "CHEBI:132962", "name": "APAP-GlcA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:65137", "map_id": "CHEBI:65137", "name": "CHEBI:65137", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:176976", "map_id": "CHEBI:176976", "name": "CHEBI:176976", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:64681", "map_id": "CHEBI:64681", "name": "CHEBI:64681", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765441", "map_id": "Q06321", "name": "ATG26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YLR189C", "map_id": "YLR189C", "name": "ATG26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789324", "map_id": "none", "name": "SLC29A1,2 transport 6MP from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9751015", "map_id": "LigandDisplayForward?ligandId=7226", "name": "6MP", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_9748998", "map_id": "LigandDisplayForward?ligandId=7226", "name": "6MP", "type": "product", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10764480", "map_id": "P31381", "name": "FUN26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YAL022C", "map_id": "YAL022C", "name": "FUN26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789290", "map_id": "none", "name": "IMPDH tetramers dehydrogenate 6TIMP to 6TXMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9748992", "map_id": "CHEBI:180684", "name": "6TIMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10763342", "map_id": "none", "name": "IMPDH tetramers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38697", "map_id": "P38697", "name": "IMD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR216W", "map_id": "YHR216W", "name": "IMD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P50095", "map_id": "P50095", "name": "IMD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR432W", "map_id": "YLR432W", "name": "IMD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P50094", "map_id": "P50094", "name": "IMD4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML056C", "map_id": "YML056C", "name": "IMD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789337", "map_id": "none", "name": "ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9753629", "map_id": "none", "name": "APAP-Cys,APAP-Mer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:133438", "map_id": "CHEBI:133438", "name": "CHEBI:133438", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9753653", "map_id": "CHEBI:133067", "name": "APAP-Cys", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9753624", "map_id": "none", "name": "APAP-Cys,APAP-Mer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:133066", "map_id": "CHEBI:133066", "name": "CHEBI:133066", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:133435", "map_id": "CHEBI:133435", "name": "CHEBI:133435", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10789334", "map_id": "none", "name": "ABCC1,4,5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P39109", "map_id": "P39109", "name": "YCF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR135C", "map_id": "YDR135C", "name": "YCF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P12866", "map_id": "P12866", "name": "STE6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789314", "map_id": "none", "name": "UGT1A6 glucuronates ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_9749997", "map_id": "CHEBI:176960", "name": "SAAG", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10765443", "map_id": "Q06321", "name": "ATG26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10789299", "map_id": "none", "name": "GUK1 phosphorylates 6TdGMP to 6TdGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9749031", "map_id": "CHEBI:180689", "name": "6TdGMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9749033", "map_id": "CHEBI:180690", "name": "6TdGDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10789332", "map_id": "none", "name": "ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9753559", "map_id": "none", "name": "APAP-GlcA, APAP-SO3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:32635", "map_id": "CHEBI:32635", "name": "CHEBI:32635", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9753562", "map_id": "none", "name": "APAP-GlcA, APAP-SO3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:32636", "map_id": "CHEBI:32636", "name": "CHEBI:32636", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10789329", "map_id": "none", "name": "ABCC3, ABCC4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P53049", "map_id": "P53049", "name": "YOR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR281W", "map_id": "YGR281W", "name": "YOR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789327", "map_id": "none", "name": "ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10772886", "map_id": "none", "name": "Homologues of ABCC2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P14772", "map_id": "P14772", "name": "BPT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLL015W", "map_id": "YLL015W", "name": "BPT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32386", "map_id": "P32386", "name": "YBT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLL048C", "map_id": "YLL048C", "name": "YBT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38735", "map_id": "P38735", "name": "VMR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHL035C", "map_id": "YHL035C", "name": "VMR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789339", "map_id": "none", "name": "CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9753680", "map_id": "CHEBI:180460", "name": "APAP-CysGly", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29424", "map_id": "CHEBI:57305", "name": "Gly", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10772689", "map_id": "none", "name": "CNDP2:2Mn2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_113527", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "P43616", "map_id": "P43616", "name": "DUG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFR044C", "map_id": "YFR044C", "name": "DUG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765448", "map_id": "none", "name": "UGTs glucuronate APAP to APAP-GlcA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_158601", "map_id": "CHEBI:58052", "name": "UDP-GlcA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9677362", "map_id": "LigandDisplayForward?ligandId=5239", "name": "APAP", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_110096", "map_id": "CHEBI:58223", "name": "UDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10789301", "map_id": "none", "name": "NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9749032", "map_id": "CHEBI:180691", "name": "6TdGTP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10770987", "map_id": "none", "name": "nucleoside diphosphate kinase 1A:5B heterohexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P36010", "map_id": "P36010", "name": "YNK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL067W", "map_id": "YKL067W", "name": "YNK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789303", "map_id": "none", "name": "NME1:2 hexamer phosphorylates 6TGDP to 6TGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9748947", "map_id": "CHEBI:180688", "name": "6TGTP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10789322", "map_id": "none", "name": "ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9750692", "map_id": "none", "name": "salicylate metabolites", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:9008", "map_id": "CHEBI:9008", "name": "CHEBI:9008", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:58044", "map_id": "CHEBI:58044", "name": "CHEBI:58044", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:88742", "map_id": "CHEBI:88742", "name": "CHEBI:88742", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:36654", "map_id": "CHEBI:36654", "name": "CHEBI:36654", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9750678", "map_id": "none", "name": "salicylate metabolites", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10789319", "map_id": "none", "name": "ABCC2, ABCC3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10789317", "map_id": "none", "name": "ABCC4 transports TPMP substrates from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9750587", "map_id": "none", "name": "ABCC4 TPMP substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "pubchem.compound:3037883", "map_id": "pubchem.compound:3037883", "name": "pubchem.compound:3037883", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9750548", "map_id": "none", "name": "ABCC4 TPMP substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:80613", "map_id": "CHEBI:80613", "name": "CHEBI:80613", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:2332", "map_id": "CHEBI:2332", "name": "CHEBI:2332", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10772888", "map_id": "P12866", "name": "STE6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10789341", "map_id": "none", "name": "GGT dimers hydrolyse APAP-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9753685", "map_id": "CHEBI:32639", "name": "APAP-SG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10777790", "map_id": "none", "name": "GGT dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q05902", "map_id": "Q05902", "name": "ECM38", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR299W", "map_id": "YLR299W", "name": "ECM38", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781056", "map_id": "none", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781053", "map_id": "none", "name": "(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_30555", "map_id": "CHEBI:16516", "name": "dNTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10781051", "map_id": "none", "name": "(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_113541", "map_id": "CHEBI:33019", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10779690", "map_id": "none", "name": "Recruitment of XPA and release of CAK ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779684", "map_id": "none", "name": "Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P47050", "map_id": "P47050", "name": "RTT101", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL047C", "map_id": "YJL047C", "name": "RTT101", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32628", "map_id": "P32628", "name": "RAD23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL037C", "map_id": "YEL037C", "name": "RAD23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06665", "map_id": "Q06665", "name": "RAD34", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR314C", "map_id": "YDR314C", "name": "RAD34", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10779650", "map_id": "P28519", "name": "RAD14", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YMR201C", "map_id": "YMR201C", "name": "RAD14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10763257", "map_id": "none", "name": "CAK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779688", "map_id": "none", "name": "Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P28519", "map_id": "P28519", "name": "RAD14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766961", "map_id": "none", "name": "COASY phosphorylates DP-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196778", "map_id": "CHEBI:15468", "name": "DP-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766945", "map_id": "P53332", "name": "CAB4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "YGR277C", "map_id": "YGR277C", "name": "CAB4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766940", "map_id": "none", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111707", "map_id": "CHEBI:35235", "name": "L-Cys", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_196786", "map_id": "CHEBI:15905", "name": "PPanK", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_196834", "map_id": "CHEBI:15769", "name": "PPC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766937", "map_id": "none", "name": "2xPPCS", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P40506", "map_id": "P40506", "name": "CAB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL083C", "map_id": "YIL083C", "name": "CAB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766948", "map_id": "none", "name": "COASY transfers an adenylyl group from ATP to PPANT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196767", "map_id": "CHEBI:16858", "name": "PPANT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10767291", "map_id": "none", "name": "SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_29374", "map_id": "CHEBI:57287", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10767288", "map_id": "P38702", "name": "LEU5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YHR002W", "map_id": "YHR002W", "name": "LEU5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766971", "map_id": "none", "name": "3xPPCDC:3FMN decarboxylates PPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_113528", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766968", "map_id": "none", "name": "3xPPCDC:3xFMN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P36076", "map_id": "P36076", "name": "CAB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL088W", "map_id": "YKL088W", "name": "CAB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_73524", "map_id": "CHEBI:17621", "name": "FMN", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10779496", "map_id": "none", "name": "MUS81 binds EME1, EME2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779488", "map_id": "Q04149", "name": "MUS81", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YDR386W", "map_id": "YDR386W", "name": "MUS81", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10779481", "map_id": "P38257", "name": "MMS4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YBR098W", "map_id": "YBR098W", "name": "MMS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10779494", "map_id": "none", "name": "MUS81:EME1, (MUS81:EME2)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P38257", "map_id": "P38257", "name": "MMS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04149", "map_id": "Q04149", "name": "MUS81", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761487", "map_id": "none", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_76213", "map_id": "CHEBI:30744", "name": "OA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29448", "map_id": "CHEBI:29991", "name": "L-Asp", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29406", "map_id": "CHEBI:16810", "name": "2OG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761484", "map_id": "none", "name": "PXLP-K259-GOT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P23542", "map_id": "P23542", "name": "AAT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR027C", "map_id": "YLR027C", "name": "AAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761500", "map_id": "none", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113594", "map_id": "CHEBI:16810", "name": "2OG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113553", "map_id": "CHEBI:29991", "name": "L-Asp", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113552", "map_id": "CHEBI:29985", "name": "L-Glu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113587", "map_id": "CHEBI:30744", "name": "OAA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10761497", "map_id": "none", "name": "GOT2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q01802", "map_id": "Q01802", "name": "AAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL106W", "map_id": "YKL106W", "name": "AAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761517", "map_id": "none", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29642", "map_id": "CHEBI:58048", "name": "L-Asn", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761514", "map_id": "none", "name": "ASNS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P49090", "map_id": "P49090", "name": "ASN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR124W", "map_id": "YGR124W", "name": "ASN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P49089", "map_id": "P49089", "name": "ASN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR145W", "map_id": "YPR145W", "name": "ASN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781277", "map_id": "none", "name": "NAALADases hydrolyse NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5693762", "map_id": "CHEBI:76931", "name": "NAAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5693772", "map_id": "CHEBI:16953", "name": "NAASP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10781274", "map_id": "none", "name": "NAALADases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q08693", "map_id": "Q08693", "name": "TRE2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR256C", "map_id": "YOR256C", "name": "TRE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47161", "map_id": "P47161", "name": "VPS70", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR126C", "map_id": "YJR126C", "name": "VPS70", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08919", "map_id": "Q08919", "name": "TRE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL176C", "map_id": "YPL176C", "name": "TRE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768525", "map_id": "none", "name": "SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. 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For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768520", "map_id": "Q12482", "name": "AGC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YPR021C", "map_id": "YPR021C", "name": "AGC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761489", "map_id": "none", "name": "PXLP-K259-GOT1 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10782324", "map_id": "none", "name": "21S pre-rRNA:SSU processome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q04177", "map_id": "Q04177", "name": "UTP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "UTP5", "map_id": "UTP5", "name": "UTP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53941", "map_id": "P53941", "name": "IMP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "IMP4", "map_id": "IMP4", "name": "IMP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02354", "map_id": "Q02354", "name": "UTP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "UTP6", "map_id": "UTP6", "name": "UTP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25368", "map_id": "P25368", "name": "RRP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RRP7", "map_id": "RRP7", "name": "RRP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04217", "map_id": "Q04217", "name": "ECM16", "type": "complex_component", "sub_type": 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"name": "UTP20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q99207", "map_id": "Q99207", "name": "NOP14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "NOP14", "map_id": "NOP14", "name": "NOP14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40362", "map_id": "P40362", "name": "UTP18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "UTP18", "map_id": "UTP18", "name": "UTP18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P34247", "map_id": "P34247", "name": "UTP11", "type": "complex_component", "sub_type": "protein_component", 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. 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"compartment_display": "none" }, { "id": "YHR197W", "map_id": "YHR197W", "name": "RIX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q07845", "map_id": "Q07845", "name": "GRC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLL035W", "map_id": "YLL035W", "name": "GRC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38803", "map_id": "P38803", "name": "IPI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR085W", "map_id": "YHR085W", "name": "IPI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36146", "map_id": "P36146", "name": "LAS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR063C", "map_id": "YKR063C", "name": "LAS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02724", "map_id": "Q02724", "name": "ULP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL020C", "map_id": "YPL020C", "name": "ULP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53877", "map_id": "P53877", "name": "IPI3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL182C", "map_id": "YNL182C", "name": "IPI3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53261", "map_id": "P53261", "name": "NOP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR103W", "map_id": "YGR103W", "name": "NOP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04660", "map_id": "Q04660", "name": "ERB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR049C", "map_id": "YMR049C", "name": "ERB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10782067", "map_id": "none", "name": "28S rRNA:12S pre-rRNA:Rix1:LAS1L:NOL9:SENP3:PeBoW", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10782063", "map_id": "Q07845", "name": "GRC3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10782098", "map_id": "none", "name": "PeBoW complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10782114", "map_id": "none", "name": "GNL3:EBNA1BP2:DDX21:PES1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P36049", "map_id": "P36049", "name": "EBP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL172W", "map_id": "YKL172W", "name": "EBP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40010", "map_id": "P40010", "name": "NUG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER006W", "map_id": "YER006W", "name": "NUG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10782058", "map_id": "P36146", "name": "LAS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10767666", "map_id": "none", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_202277", "map_id": "none", "name": "PIP3, PI(3,4)P2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_202247", "map_id": "CHEBI:16152", "name": "PI(3,4)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10767664", "map_id": "none", "name": "PDK1:PIP2,PIP3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10767681", "map_id": "none", "name": "Phosphorylation of PKC theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10767671", "map_id": "none", "name": "p-Y90-PKC-theta:DAG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10767678", "map_id": "none", "name": "Active PKC theta bound to DAG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10767319", "map_id": "none", "name": "PTEN dephosphorylates PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_179856", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10767316", "map_id": "P53916", "name": "TEP1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YNL128W", "map_id": "YNL128W", "name": "phospho-TEP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767687", "map_id": "none", "name": "Translocation of PKC theta to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. 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"compartment_display": "none" }, { "id": "YJL140W", "map_id": "YJL140W", "name": "RPB4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P16370", "map_id": "P16370", "name": "RPB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL021W", "map_id": "YIL021W", "name": "RPB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41895", "map_id": "P41895", "name": "TFG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR186W", "map_id": "YGR186W", "name": "TFG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36145", "map_id": "P36145", "name": "TFA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR062W", "map_id": "YKR062W", "name": "TFA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P34087", "map_id": "P34087", "name": "RPB7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR404C", "map_id": "YDR404C", "name": "RPB7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P11747", "map_id": "P11747", "name": "TAF13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML098W", "map_id": "YML098W", "name": "TAF13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764070", "map_id": "none", "name": "pol II closed pre-initiation complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764504", "map_id": "none", "name": "Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10763800", "map_id": "none", "name": "pol II promoter:TFIID complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10763417", "map_id": "none", "name": "TFIIA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10763422", "map_id": "P29055", "name": "SUA7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10763802", "map_id": "none", "name": "pol II promoter:TFIID:TFIIA:TFIIB complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10763808", "map_id": "none", "name": "Binding of TFIIE to the growing preinitiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10763503", "map_id": "none", "name": "TFIIE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10763804", "map_id": "none", "name": "pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764502", "map_id": "none", "name": "Recognition and Binding of Core Promoter Elements by TFIID", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_109627", "map_id": "none", "name": "DNA containing RNA Polymerase II promoter", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10763491", "map_id": "none", "name": "TFIID", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764506", "map_id": "none", "name": "Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10762312", "map_id": "none", "name": "RNA Polymerase II (unphosphorylated):TFIIF complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10769195", "map_id": "none", "name": "Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_114520", "map_id": "CHEBI:16595", "name": "I(1,4,5)P3", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10769192", "map_id": "none", "name": "PLC beta1,2,3:G-alpha(q):GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P32383", "map_id": "P32383", "name": "PLC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL268W", "map_id": "YPL268W", "name": "PLC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772682", "map_id": "none", "name": "MTA is cleaved and phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353106", "map_id": "CHEBI:17509", "name": "MTAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_83951", "map_id": "CHEBI:16708", "name": "Ade", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1237165", "map_id": "CHEBI:58533", "name": "MTRIBP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772679", "map_id": "none", "name": "MTAP trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q07938", "map_id": "Q07938", "name": "MEU1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR017W", "map_id": "YLR017W", "name": "MEU1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772662", "map_id": "none", "name": "Acireductone is oxidized to MOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1237155", "map_id": "CHEBI:58795", "name": "Acireductone", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29368", "map_id": "CHEBI:15379", "name": "O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1237122", "map_id": "CHEBI:16723", "name": "4MTOBUTA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29460", "map_id": "CHEBI:30751", "name": "HCOOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772659", "map_id": "none", "name": "ARD:Fe++", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q03677", "map_id": "Q03677", "name": "ADI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR009W", "map_id": "YMR009W", "name": "ADI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772652", "map_id": "none", "name": "Methylthio-ribose-P = Methylthio-ribulose-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1237107", "map_id": "CHEBI:58548", "name": "MTRIBUP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772649", "map_id": "Q06489", "name": "MRI1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YPR118W", "map_id": "YPR118W", "name": "MRI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772672", "map_id": "none", "name": "Acireductone is created", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1237176", "map_id": "CHEBI:58828", "name": "2,3-DMPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772669", "map_id": "none", "name": "E1:Mg++", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32626", "map_id": "P32626", "name": "UTR4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL038W", "map_id": "YEL038W", "name": "UTR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787565", "map_id": "none", "name": "cAMP binds PKA tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764953", "map_id": "none", "name": "PKA tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P05986", "map_id": "P05986", "name": "TPK3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL166C", "map_id": "YKL166C", "name": "TPK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P06245", "map_id": "P06245", "name": "TPK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL203W", "map_id": "YPL203W", "name": "TPK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P07278", "map_id": "P07278", "name": "BCY1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL033C", "map_id": "YIL033C", "name": "BCY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P06244", "map_id": "P06244", "name": "TPK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL164C", "map_id": "YJL164C", "name": "TPK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_30389", "map_id": "CHEBI:17489", "name": "cAMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10764955", "map_id": "none", "name": "PKA tetramer:4xcAMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788654", "map_id": "none", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788647", "map_id": "none", "name": "CaMKK:CALM1:4xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10788651", "map_id": "none", "name": "p-CaMKK:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788663", "map_id": "none", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788659", "map_id": "P38623", "name": "RCK2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YLR248W", "map_id": "YLR248W", "name": "RCK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788661", "map_id": "none", "name": "CAMK1:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38623", "map_id": "P38623", "name": "RCK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764959", "map_id": "none", "name": "cAMP induces dissociation of inactive PKA tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764957", "map_id": "none", "name": "cAMP:PKA regulatory subunit", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10764951", "map_id": "none", "name": "PKA catalytic subunit", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10789248", "map_id": "none", "name": "RHOC activates endoplasmic reticulum effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10789244", "map_id": "none", "name": "RHOC endoplasmic reticulum effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q01590", "map_id": "Q01590", "name": "SED5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR026C", "map_id": "YLR026C", "name": "SED5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12396", "map_id": "Q12396", "name": "EMP46", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR080W", "map_id": "YLR080W", "name": "EMP46", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P43555", "map_id": "P43555", "name": "EMP47", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFL048C", "map_id": "YFL048C", "name": "EMP47", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36137", "map_id": "P36137", "name": "UIP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR044W", "map_id": "YKR044W", "name": "UIP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40075", "map_id": "P40075", "name": "SCS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER120W", "map_id": "YER120W", "name": "SCS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32462", "map_id": "P32462", "name": "ERG24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL280C", "map_id": "YNL280C", "name": "ERG24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q6Q595", "map_id": "Q6Q595", "name": "SCS22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL091C-A", "map_id": "YBL091C-A", "name": "SCS22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10789214", "map_id": "none", "name": "RHOC:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q00245", "map_id": "Q00245", "name": "RHO3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL118W", "map_id": "YIL118W", "name": "RHO3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q00246", "map_id": "Q00246", "name": "RHO4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR055W", "map_id": "YKR055W", "name": "RHO4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P06781", "map_id": "P06781", "name": "RHO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL090W", "map_id": "YNL090W", "name": "RHO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P06780", "map_id": "P06780", "name": "RHO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR165W", "map_id": "YPR165W", "name": "RHO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10789246", "map_id": "none", "name": "RHOC:GTP:RHOC endoplasmic reticulum effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10788156", "map_id": "none", "name": "RHOD GAPs stimulate RHOD GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10788136", "map_id": "none", "name": "RHOD:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10788124", "map_id": "none", "name": "RHOD:GDP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10788153", "map_id": "none", "name": "RHOD GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P39960", "map_id": "P39960", "name": "BEM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER155C", "map_id": "YER155C", "name": "BEM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06407", "map_id": "Q06407", "name": "RGA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR379W", "map_id": "YDR379W", "name": "RGA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38339", "map_id": "P38339", "name": "RGD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR260C", "map_id": "YBR260C", "name": "RGD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32873", "map_id": "P32873", "name": "BEM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL115C", "map_id": "YPL115C", "name": "BEM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39083", "map_id": "P39083", "name": "RGA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR127W", "map_id": "YOR127W", "name": "RGA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32525", "map_id": "P32525", "name": "ECM25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL201W", "map_id": "YJL201W", "name": "ECM25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789129", "map_id": "none", "name": "RHOD binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10788063", "map_id": "none", "name": "Homologues of PAK5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P48562", "map_id": "P48562", "name": "CLA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL298W", "map_id": "YNL298W", "name": "CLA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03497", "map_id": "Q03497", "name": "STE20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHL007C", "map_id": "YHL007C", "name": "STE20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12469", "map_id": "Q12469", "name": "SKM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL113W", "map_id": "YOL113W", "name": "SKM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10789123", "map_id": "none", "name": "RHOD:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10789127", "map_id": "none", "name": "RHOD:GTP:RHOD mitochondrial outer membrane effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10788047", "map_id": "none", "name": "GDIs block activation of RHOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787983", "map_id": "Q12434", "name": "RDI1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YDL135C", "map_id": "YDL135C", "name": "RDI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788033", "map_id": "none", "name": "RHOC:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10788045", "map_id": "none", "name": "RHOC:GDP:ARHGDIA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q12434", "map_id": "Q12434", "name": "RDI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789250", "map_id": "none", "name": "RHOC translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10778611", "map_id": "none", "name": "RHOC:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788248", "map_id": "none", "name": "RHOU auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10788245", "map_id": "none", "name": "RHOU:GDP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P19073", "map_id": "P19073", "name": "CDC42", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR229C", "map_id": "YLR229C", "name": "CDC42", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788230", "map_id": "none", "name": "RHOU:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788109", "map_id": "none", "name": "CDC42 GAPs stimulate CDC42 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10768894", "map_id": "none", "name": "CDC42:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10788091", "map_id": "none", "name": "CDC42:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10788106", "map_id": "none", "name": "CDC42 GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q12128", "map_id": "Q12128", "name": "BAG7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR134W", "map_id": "YOR134W", "name": "BAG7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P17121", "map_id": "P17121", "name": "SAC7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR389W", "map_id": "YDR389W", "name": "SAC7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789177", "map_id": "none", "name": "RND3 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10789173", "map_id": "none", "name": "Homologues of RND3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10789175", "map_id": "none", "name": "RND3:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788020", "map_id": "none", "name": "GDIs block activation of RHOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788014", "map_id": "Q12434", "name": "RDI1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10788012", "map_id": "none", "name": "RHOB:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10788018", "map_id": "none", "name": "RHOB:GDP:RHOB GDIs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788031", "map_id": "none", "name": "RHOB binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788027", "map_id": "none", "name": "RHOB effectors (plasma membrane)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P40357", "map_id": "P40357", "name": "SEC9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR009C", "map_id": "YGR009C", "name": "SEC9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12280", "map_id": "Q12280", "name": "IQG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL242C", "map_id": "YPL242C", "name": "IQG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P33328", "map_id": "P33328", "name": "SNC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR327C", "map_id": "YOR327C", "name": "SNC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04359", "map_id": "Q04359", "name": "SPO20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR017W", "map_id": "YMR017W", "name": "SPO20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788022", "map_id": "none", "name": "RHOB:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10788029", "map_id": "none", "name": "RHOB:GTP:cytosolic RHOB effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788295", "map_id": "none", "name": "RAC3 GAPs stimulate RAC3 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10788278", "map_id": "none", "name": "RAC3:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P53879", "map_id": "P53879", "name": "RHO5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL180C", "map_id": "YNL180C", "name": "RHO5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788276", "map_id": "none", "name": "RAC3:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10788292", "map_id": "none", "name": "RAC3 GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08227", "map_id": "Q08227", "name": "INP54", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL065C", "map_id": "YOL065C", "name": "INP54", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10788305", "map_id": "none", "name": "RAC3 GDIs block activation of RAC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10788297", "map_id": "none", "name": "RAC3 GDIs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10788303", "map_id": "none", "name": "RAC3:GDP:RAC3 GDIs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10789282", "map_id": "none", "name": "Phosphorylated RHOU translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10789276", "map_id": "none", "name": "p-Y254-RHOU:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10789280", "map_id": "none", "name": "p-Y254-RHOU:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10788265", "map_id": "none", "name": "RHOV binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10788252", "map_id": "none", "name": "RHOV:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10788261", "map_id": "none", "name": "RHOV effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08924", "map_id": "Q08924", "name": "RTT10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL183C", "map_id": "YPL183C", "name": "RTT10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22137", "map_id": "P22137", "name": "CHC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL206C", "map_id": "YGL206C", "name": "CHC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P17536", "map_id": "P17536", "name": "TPM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL079C", "map_id": "YNL079C", "name": "TPM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788263", "map_id": "none", "name": "RHOV:GTP:RHOV effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788184", "map_id": "none", "name": "RHOD binds effectors at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10788168", "map_id": "none", "name": "RHOD:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "species_10788180", "map_id": "none", "name": "RHOD endosome effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P40578", "map_id": "P40578", "name": "MGA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIR033W", "map_id": "YIR033W", "name": "MGA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P35210", "map_id": "P35210", "name": "SPT23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL020C", "map_id": "YKL020C", "name": "SPT23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12091", "map_id": "Q12091", "name": "DAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL170W", "map_id": "YPL170W", "name": "DAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788182", "map_id": "none", "name": "RHOD:GTP:RHOD endosome effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10787825", "map_id": "none", "name": "RHOA GAPs stimulate RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10765231", "map_id": "none", "name": "RHOA:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10765229", "map_id": "none", "name": "RHOA:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10787822", "map_id": "none", "name": "RHOA GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788139", "map_id": "none", "name": "RHOD auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10789125", "map_id": "none", "name": "RHOD translocates to the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10789143", "map_id": "none", "name": "RHOD translocates to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10789141", "map_id": "none", "name": "RHOD:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10788102", "map_id": "none", "name": "CDC42 GEFs activate CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10788099", "map_id": "none", "name": "CDC42 GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q05670", "map_id": "Q05670", "name": "FUS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR232W", "map_id": "YMR232W", "name": "FUS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P34216", "map_id": "P34216", "name": "EDE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL047C", "map_id": "YBL047C", "name": "EDE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789145", "map_id": "none", "name": "RHOF GAPs stimulate RHOF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10789100", "map_id": "none", "name": "RHOF:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10789098", "map_id": "none", "name": "RHOF:GDP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788269", "map_id": "none", "name": "RHOV binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10788267", "map_id": "none", "name": "RHOV:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10787993", "map_id": "none", "name": "RHOA:GTP translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10787991", "map_id": "none", "name": "RHOA:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10787743", "map_id": "none", "name": "RHOA GEFs activate RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787740", "map_id": "none", "name": "RHOA GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q06409", "map_id": "Q06409", "name": "DCK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR422W", "map_id": "YLR422W", "name": "DCK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789092", "map_id": "none", "name": "RHOB translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10778663", "map_id": "none", "name": "RHOB:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10788010", "map_id": "none", "name": "RHOA binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10788006", "map_id": "none", "name": "RHOA plasma membrane effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P22213", "map_id": "P22213", "name": "SLY1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR189W", "map_id": "YDR189W", "name": "SLY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12229", "map_id": "Q12229", "name": "UBX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL091C", "map_id": "YDL091C", "name": "UBX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40513", "map_id": "P40513", "name": "MAM33", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL070C", "map_id": "YIL070C", "name": "MAM33", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36126", "map_id": "P36126", "name": "SPO14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR031C", "map_id": "YKR031C", "name": "SPO14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04228", "map_id": "Q04228", "name": "UBX2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML013W", "map_id": "YML013W", "name": "UBX2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788008", "map_id": "none", "name": "RHOA:GTP:cytosolic RHOA effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788053", "map_id": "none", "name": "RHOC binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10788049", "map_id": "none", "name": "RHOC effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10788051", "map_id": "none", "name": "RHOC:GTP:RHOC effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788186", "map_id": "none", "name": "RHOD:GTP translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10789194", "map_id": "none", "name": "RND1 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769249", "map_id": "none", "name": "RND1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10789190", "map_id": "none", "name": "RND1 effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P19158", "map_id": "P19158", "name": "IRA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL081W", "map_id": "YOL081W", "name": "IRA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P01120", "map_id": "P01120", "name": "RAS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL098C", "map_id": "YNL098C", "name": "RAS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04458", "map_id": "Q04458", "name": "HFD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR110C", "map_id": "YMR110C", "name": "HFD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P15705", "map_id": "P15705", "name": "STI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR027W", "map_id": "YOR027W", "name": "STI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P18963", "map_id": "P18963", "name": "IRA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR140C", "map_id": "YBR140C", "name": "IRA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10789192", "map_id": "none", "name": "RND1:GTP:RND1 effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788055", "map_id": "none", "name": "RHOC GAPs stimulate RHOC GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10787796", "map_id": "P32525", "name": "ECM25", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10789111", "map_id": "none", "name": "RHOD binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10789107", "map_id": "none", "name": "RHOD plasma membrane effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P13517", "map_id": "P13517", "name": "CAP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL034C", "map_id": "YIL034C", "name": "CAP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P15891", "map_id": "P15891", "name": "ABP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCR088W", "map_id": "YCR088W", "name": "ABP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32939", "map_id": "P32939", "name": "YPT7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML001W", "map_id": "YML001W", "name": "YPT7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10789109", "map_id": "none", "name": "RHOD:GTP:RHOD plasma membrane effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10789196", "map_id": "none", "name": "RND1 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769247", "map_id": "none", "name": "Homologues of RND1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10789103", "map_id": "none", "name": "RHOF auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10787989", "map_id": "none", "name": "GDIs block activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787987", "map_id": "none", "name": "RHOA GDIs:RHOA:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10789096", "map_id": "none", "name": "CDC42 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10789094", "map_id": "none", "name": "CDC42:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10788243", "map_id": "none", "name": "RHOU binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10788239", "map_id": "none", "name": "RHOU effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P53281", "map_id": "P53281", "name": "LSB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR136W", "map_id": "YGR136W", "name": "LSB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39940", "map_id": "P39940", "name": "RSP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER125W", "map_id": "YER125W", "name": "RSP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38753", "map_id": "P38753", "name": "HSE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHL002W", "map_id": "YHL002W", "name": "HSE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39013", "map_id": "P39013", "name": "END3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL084C", "map_id": "YNL084C", "name": "END3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32521", "map_id": "P32521", "name": "PAN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIR006C", "map_id": "YIR006C", "name": "PAN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788241", "map_id": "none", "name": "RHOU:GTP:RHOU effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788095", "map_id": "none", "name": "CDC42 GDIs block activation of CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10788093", "map_id": "none", "name": "CDC42:GDP:CDC42 GDIs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788025", "map_id": "none", "name": "RHOB GAPs stimulate RHOB GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10789198", "map_id": "none", "name": "RND2 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10789161", "map_id": "none", "name": "Homologues of RND2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10789163", "map_id": "none", "name": "RND2:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10789256", "map_id": "none", "name": "RAC3 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10789254", "map_id": "none", "name": "RAC3:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10764078", "map_id": "none", "name": "Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764066", "map_id": "none", "name": "Pol II initiation complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_6806881", "map_id": "CHEBI:61557", "name": "NTP(4-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10764074", "map_id": "none", "name": "Pol II Initiation complex with phosphodiester-PPi intermediate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764086", "map_id": "none", "name": "Addition of Nucleotides 5 through 9 on the growing Transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764080", "map_id": "none", "name": "pol II transcription complex containing 4 nucleotide long transcript", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764084", "map_id": "none", "name": "pol II transcription complex containing 9 nucleotide long transcript", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764068", "map_id": "none", "name": "NTP Binds Active Site of RNA Polymerase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764062", "map_id": "none", "name": "pol II open pre-initiation complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764035", "map_id": "none", "name": "Addition of the third nucleotide on the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10763505", "map_id": "none", "name": "pol II transcription complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764032", "map_id": "none", "name": "pol II transcription complex containing 3 Nucleotide long transcript", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764285", "map_id": "none", "name": "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764283", "map_id": "none", "name": "pol II transcription complex containing 11 nucleotide long transcript", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764082", "map_id": "none", "name": "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10788639", "map_id": "none", "name": "Unwinding DNA for the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10788637", "map_id": "none", "name": "Unwinding of DNA for the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_164121", "map_id": "CHEBI:456215", "name": "AMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10764076", "map_id": "none", "name": "Newly Formed Phosphodiester Bond Stabilized and PPi Released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10764162", "map_id": "none", "name": "RNA Polymerase II Promoter Opening: First Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113550", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10764829", "map_id": "none", "name": "Addition of nucleotides between position +11 and +30", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764338", "map_id": "none", "name": "Pol II transcription complex containing extruded transcript to +30", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10780889", "map_id": "none", "name": "USP5 cleaves polyubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10780884", "map_id": "none", "name": "USP5:PolyUb", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38237", "map_id": "P38237", "name": "UBP14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR058C", "map_id": "YBR058C", "name": "UBP14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10780886", "map_id": "none", "name": "USP5:Ub", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10781695", "map_id": "none", "name": "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781688", "map_id": "none", "name": "USP37:RUVLB1:PSMC5:PolyUb-CCNA1,PolyUb-CCNA2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q03940", "map_id": "Q03940", "name": "RVB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR190C", "map_id": "YDR190C", "name": "RVB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38187", "map_id": "P38187", "name": "UBP13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL067C", "map_id": "YBL067C", "name": "UBP13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113518", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10780391", "map_id": "none", "name": "PolyUb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10781692", "map_id": "none", "name": "USP37:RUVLB1:PSMC5:CCNA1,CCNA2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10780495", "map_id": "none", "name": "USP3,SAGA deubiquitinate Histone H2A,H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10780488", "map_id": "none", "name": "USP3,SAGA:Ub-histone H2A, Ub-histone H2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P50102", "map_id": "P50102", "name": "UBP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR223W", "map_id": "YMR223W", "name": "UBP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P28003", "map_id": "P28003", "name": "FUN19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL034C", "map_id": "YAL034C", "name": "FUN19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32494", "map_id": "P32494", "name": "NGG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR176W", "map_id": "YDR176W", "name": "NGG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q99326", "map_id": "Q99326", "name": "TADA2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR338W", "map_id": "YOR338W", "name": "TADA2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02336", "map_id": "Q02336", "name": "ADA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR448W", "map_id": "YDR448W", "name": "ADA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03330", "map_id": "Q03330", "name": "GCN5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR252W", "map_id": "YGR252W", "name": "GCN5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10780492", "map_id": "none", "name": "USP3,SAGA:Histone H2A,Histone H2B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10771848", "map_id": "none", "name": "CYLD mediated deubiquitination of DDX58 (RIG-I)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10771819", "map_id": "none", "name": "Homologues of K63polyUb-DDX58", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P40434", "map_id": "P40434", "name": "DDX58", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML133C", "map_id": "YML133C", "name": "DDX58", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40889", "map_id": "P40889", "name": "DDX58", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q7M4S9", "map_id": "Q7M4S9", "name": "DDX58", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03099", "map_id": "Q03099", "name": "DDX58", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53819", "map_id": "P53819", "name": "YRF1-6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL339C", "map_id": "YNL339C", "name": "YRF1-6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q99208", "map_id": "Q99208", "name": "DDX58", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q07888", "map_id": "Q07888", "name": "DDX58", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38721", "map_id": "P38721", "name": "DDX58", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10771837", "map_id": "none", "name": "Homologues of DDX58", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10771845", "map_id": "none", "name": "Homologues of CYLD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P33442", "map_id": "P33442", "name": "RPS1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPS1A", "map_id": "RPS1A", "name": "RPS1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10779645", "map_id": "none", "name": "ADRM1:26S proteaseome binds USP14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10779636", "map_id": "none", "name": "ADRM1:26S proteasome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10779641", "map_id": "P43593", "name": "UBP6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YFR010W", "map_id": "YFR010W", "name": "UBP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10779643", "map_id": "none", "name": "ADRM1:26S proteasome:USP14", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P43593", "map_id": "P43593", "name": "UBP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781707", "map_id": "none", "name": "USP13 deubiquitinates BECN1,USP10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10781702", "map_id": "none", "name": "USP13:K63polyUb-BECN1,K63polyUb-USP10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q02948", "map_id": "Q02948", "name": "phospho-VPS30", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL120W", "map_id": "YPL120W", "name": "phospho-VPS30", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10781704", "map_id": "none", "name": "USP13:BECN1,USP10", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10766135", "map_id": "none", "name": "K63polyUb", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10780394", "map_id": "none", "name": "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779716", "map_id": "none", "name": "USP7:PolyUb-TP53,PolyUb-MDM2,PolyUb-MDM4,PolyUb-FOXO4,PolyUb-PTEN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q05024", "map_id": "Q05024", "name": "TRI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR233W", "map_id": "YMR233W", "name": "TRI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P50101", "map_id": "P50101", "name": "UBP15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR304W", "map_id": "YMR304W", "name": "UBP15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08747", "map_id": "Q08747", "name": "UAF30", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR295W", "map_id": "YOR295W", "name": "UAF30", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53916", "map_id": "P53916", "name": "phospho-TEP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10779722", "map_id": "none", "name": "USP7:TP53,MDM2,MDM4,FOXO4,PTEN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10761428", "map_id": "none", "name": "PXLP-K314-GPT transaminates L-Ala to form PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29432", "map_id": "CHEBI:57972", "name": "L-Ala", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29398", "map_id": "CHEBI:15361", "name": "PYR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761425", "map_id": "none", "name": "PXLP-K314-GPT dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P52893", "map_id": "P52893", "name": "ALT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR089C", "map_id": "YLR089C", "name": "ALT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771076", "map_id": "none", "name": "PXLP-K341-GPT2 transaminates PYR to form L-Ala", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113557", "map_id": "CHEBI:15361", "name": "PYR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_379697", "map_id": "CHEBI:57972", "name": "L-Ala", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10771073", "map_id": "none", "name": "PXLP-K341-GPT2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P52892", "map_id": "P52892", "name": "ALT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR111C", "map_id": "YDR111C", "name": "ALT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787978", "map_id": "none", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9012724", "map_id": "CHEBI:17137", "name": "HSO3-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_9012592", "map_id": "CHEBI:16208", "name": "3MPYR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_1614595", "map_id": "CHEBI:16094", "name": "S2O3(2-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10787975", "map_id": "Q08686", "name": "TUM1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "YOR251C", "map_id": "YOR251C", "name": "TUM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10788188", "map_id": "none", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9013199", "map_id": "CHEBI:18407", "name": "HCN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_9013191", "map_id": "CHEBI:29200", "name": "HSCN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10788112", "map_id": "none", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9013207", "map_id": "CHEBI:17359", "name": "SO3(2-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10788190", "map_id": "none", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9013543", "map_id": "LigandDisplayForward?ligandId=9830", "name": "sulfanegen", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10773393", "map_id": "none", "name": "Excess homocysteine yields homolanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174369", "map_id": "CHEBI:17230", "name": "HCYS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1614532", "map_id": "CHEBI:16136", "name": "H2S", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1614594", "map_id": "CHEBI:62856", "name": "HLAN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773390", "map_id": "none", "name": "PXLP-K212-CTH tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P31373", "map_id": "P31373", "name": "CYS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL012W", "map_id": "YAL012W", "name": "CYS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773404", "map_id": "none", "name": "Homocysteine is degraded to oxobutanoate and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29382", "map_id": "CHEBI:16134", "name": "NH3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_936714", "map_id": "CHEBI:30831", "name": "2OBUTA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773399", "map_id": "none", "name": "Excess cysteine yields lanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1614582", "map_id": "CHEBI:21347", "name": "L-Lanthionine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773401", "map_id": "none", "name": "Cysteine is degraded to serine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_200736", "map_id": "CHEBI:33384", "name": "L-Ser", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10788493", "map_id": "none", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10788491", "map_id": "Q08686", "name": "TUM1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10773382", "map_id": "none", "name": "Sulfate is exported to the cytosol in exchange for dicarboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1614584", "map_id": "CHEBI:16189", "name": "SO4(2-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_198498", "map_id": "CHEBI:30797", "name": "MAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_174375", "map_id": "CHEBI:16189", "name": "SO4(2-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_113544", "map_id": "CHEBI:30797", "name": "MAL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10768552", "map_id": "Q06143", "name": "DIC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YLR348C", "map_id": "YLR348C", "name": "DIC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10778010", "map_id": "none", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778008", "map_id": "none", "name": "ARF4:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P11076", "map_id": "P11076", "name": "ARF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL192W", "map_id": "YDL192W", "name": "ARF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P19146", "map_id": "P19146", "name": "ARF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL137W", "map_id": "YDL137W", "name": "ARF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10778006", "map_id": "none", "name": "ARF4:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10768383", "map_id": "none", "name": "Homologues of GBF1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "P47102", "map_id": "P47102", "name": "GEA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR031C", "map_id": "YJR031C", "name": "GEA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39993", "map_id": "P39993", "name": "GEA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL022W", "map_id": "YEL022W", "name": "GEA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06836", "map_id": "Q06836", "name": "SYT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR095C", "map_id": "YPR095C", "name": "SYT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773127", "map_id": "none", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[11]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_426639", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1498733", "map_id": "CHEBI:28914", "name": "1-acyl LPI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10773124", "map_id": "none", "name": "PLA2(11)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773178", "map_id": "none", "name": "PI is hydrolyzed to 2-acyl LPI by PLA2[13]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498737", "map_id": "CHEBI:62746", "name": "2-acyl LPI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10773175", "map_id": "none", "name": "PLA2(13)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773030", "map_id": "none", "name": "2-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10772972", "map_id": "Q08548", "name": "ALE1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10772975", "map_id": "none", "name": "1-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10773155", "map_id": "none", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[12]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10764802", "map_id": "none", "name": "POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764798", "map_id": "none", "name": "MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764794", "map_id": "Q04049", "name": "RAD30", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YDR419W", "map_id": "YDR419W", "name": "RAD30", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764800", "map_id": "none", "name": "POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q04049", "map_id": "Q04049", "name": "RAD30", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764811", "map_id": "none", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_29604", "map_id": "CHEBI:61404", "name": "dATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10764808", "map_id": "none", "name": "POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778443", "map_id": "none", "name": "SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778439", "map_id": "none", "name": "NPLOC4:UFD1L:VCP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P33755", "map_id": "P33755", "name": "NPL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR170C", "map_id": "YBR170C", "name": "NPL4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53044", "map_id": "P53044", "name": "UFD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR048W", "map_id": "YGR048W", "name": "UFD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25694", "map_id": "P25694", "name": "CDC48", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL126C", "map_id": "YDL126C", "name": "CDC48", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10778423", "map_id": "none", "name": "SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10778441", "map_id": "none", "name": "NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778448", "map_id": "none", "name": "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778445", "map_id": "none", "name": "NPLOC4:UFD1L:VPC:SPRTN:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-Template DNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764818", "map_id": "none", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764815", "map_id": "none", "name": "POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10785235", "map_id": "none", "name": "PNPLA6 hydrolyzes LysoPtdCho", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6814253", "map_id": "CHEBI:58168", "name": "LysoPtdCho", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1498750", "map_id": "CHEBI:16870", "name": "GPCho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10785232", "map_id": "Q04958", "name": "NTE1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YML059C", "map_id": "YML059C", "name": "NTE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785323", "map_id": "none", "name": "ENPP6 hydrolyzes lysophosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_109276", "map_id": "CHEBI:15377", "name": "H2O", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_2239407", "map_id": "CHEBI:60479", "name": "lysophosphatidylcholine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_6814794", "map_id": "CHEBI:18132", "name": "ChoP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_6814795", "map_id": "CHEBI:17408", "name": "MAG", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10785320", "map_id": "none", "name": "Homologues of ENPP6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P39997", "map_id": "P39997", "name": "NPP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL016C", "map_id": "YEL016C", "name": "NPP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25353", "map_id": "P25353", "name": "NPP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCR026C", "map_id": "YCR026C", "name": "NPP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773783", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_994141", "map_id": "CHEBI:16322", "name": "I(1,3,4,5,6)P5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629770", "map_id": "CHEBI:17401", "name": "IP6", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773780", "map_id": "Q06667", "name": "IPK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YDR315C", "map_id": "YDR315C", "name": "IPK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773735", "map_id": "none", "name": "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2023968", "map_id": "none", "name": "(PP)2-IP4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:62924", "map_id": "CHEBI:62924", "name": "CHEBI:62924", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_2023931", "map_id": "CHEBI:62923", "name": "1,5-(PP)2-IP4", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_1629765", "map_id": "CHEBI:30164", "name": "5-PP-IP5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773732", "map_id": "none", "name": "NUDT(1)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q99321", "map_id": "Q99321", "name": "DDP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR163W", "map_id": "YOR163W", "name": "DDP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773751", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023901", "map_id": "CHEBI:16322", "name": "I(1,3,4,5,6)P5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2023929", "map_id": "CHEBI:17401", "name": "IP6", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10773748", "map_id": "Q06667", "name": "IPK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10773839", "map_id": "none", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_994170", "map_id": "CHEBI:16783", "name": "I(1,3,4,5)P4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_994123", "map_id": "CHEBI:18228", "name": "I(1,3,4)P3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773740", "map_id": "none", "name": "INPP5(4)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P50942", "map_id": "P50942", "name": "INP52", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL106C", "map_id": "YNL106C", "name": "INP52", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773738", "map_id": "none", "name": "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2023943", "map_id": "none", "name": "PP-IP4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_1629736", "map_id": "CHEBI:62926", "name": "1-PP-IP4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2023922", "map_id": "CHEBI:62928", "name": "5-PP-IP4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "CHEBI:62927", "map_id": "CHEBI:62927", "name": "CHEBI:62927", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10773726", "map_id": "none", "name": "NUDT4:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773870", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629755", "map_id": "CHEBI:62928", "name": "5-PP-IP4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773712", "map_id": "none", "name": "IP6K1/3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P07250", "map_id": "P07250", "name": "ARG82", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR173C", "map_id": "YDR173C", "name": "ARG82", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12494", "map_id": "Q12494", "name": "KCS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR017C", "map_id": "YDR017C", "name": "KCS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773743", "map_id": "none", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629739", "map_id": "CHEBI:17816", "name": "I(1,4)P2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773702", "map_id": "none", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023932", "map_id": "CHEBI:62919", "name": "1-PP-IP5", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10773699", "map_id": "none", "name": "IP6K1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10773778", "map_id": "none", "name": "Glc6P is isomerised to I3P by ISYNA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629756", "map_id": "CHEBI:4170", "name": "Glc6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629731", "map_id": "CHEBI:18169", "name": "I3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773775", "map_id": "none", "name": "ISYNA1:NAD+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_113526", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "P11986", "map_id": "P11986", "name": "INO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL153C", "map_id": "YJL153C", "name": "INO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773810", "map_id": "none", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10773807", "map_id": "none", "name": "PTEN:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773826", "map_id": "none", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10773821", "map_id": "Q08227", "name": "INP54", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10773715", "map_id": "none", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629759", "map_id": "CHEBI:62985", "name": "5-PPP-IP5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773968", "map_id": "none", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2023974", "map_id": "none", "name": "1/3-PP-IP5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:62922", "map_id": "CHEBI:62922", "name": "CHEBI:62922", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773816", "map_id": "none", "name": "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_426910", "map_id": "CHEBI:17268", "name": "Ins", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773680", "map_id": "none", "name": "IMPA1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38710", "map_id": "P38710", "name": "INM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR046C", "map_id": "YHR046C", "name": "INM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05533", "map_id": "Q05533", "name": "INM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR287W", "map_id": "YDR287W", "name": "INM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773864", "map_id": "none", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10773861", "map_id": "none", "name": "PLCdegh", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10773813", "map_id": "none", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023940", "map_id": "CHEBI:30164", "name": "5-PP-IP5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10773867", "map_id": "none", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10773786", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10773876", "map_id": "none", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10773768", "map_id": "none", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10773765", "map_id": "none", "name": "PLCbz", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773799", "map_id": "none", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629738", "map_id": "CHEBI:62931", "name": "1,5-(PP)2-IP3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773836", "map_id": "none", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629740", "map_id": "CHEBI:62919", "name": "1-PP-IP5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773791", "map_id": "Q06685", "name": "VIP1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YLR410W", "map_id": "YLR410W", "name": "VIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773873", "map_id": "none", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023941", "map_id": "CHEBI:62985", "name": "5-PPP-IP5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10773805", "map_id": "none", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10773819", "map_id": "none", "name": "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629753", "map_id": "CHEBI:18384", "name": "I4P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773796", "map_id": "none", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629732", "map_id": "CHEBI:62923", "name": "1,5-(PP)2-IP4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773970", "map_id": "none", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10773879", "map_id": "none", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023948", "map_id": "CHEBI:62931", "name": "1,5-(PP)2-IP3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10773802", "map_id": "none", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10773833", "map_id": "none", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2023856", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1500596", "map_id": "CHEBI:17815", "name": "DAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10773830", "map_id": "none", "name": "PLCD4:3xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10773683", "map_id": "none", "name": "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_870330", "map_id": "CHEBI:18297", "name": "I1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10778372", "map_id": "none", "name": "USP43 binds ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778364", "map_id": "none", "name": "Homologues of USP43", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P39538", "map_id": "P39538", "name": "phospho-UBP12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL197W", "map_id": "YJL197W", "name": "phospho-UBP12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32571", "map_id": "P32571", "name": "phospho-DOA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR069C", "map_id": "YDR069C", "name": "phospho-DOA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39944", "map_id": "P39944", "name": "phospho-UBP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER144C", "map_id": "YER144C", "name": "phospho-UBP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10778368", "map_id": "none", "name": "ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10778370", "map_id": "none", "name": "USP43:ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778378", "map_id": "none", "name": "POLD,POLE binds deISGylated PCNA after TLS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778374", "map_id": "none", "name": "PCNA:RPA:RFC:TLS-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764822", "map_id": "none", "name": "POLD,POLE", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P40366", "map_id": "P40366", "name": "DLS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL065C", "map_id": "YJL065C", "name": "DLS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P27344", "map_id": "P27344", "name": "DPB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR278W", "map_id": "YBR278W", "name": "DPB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04603", "map_id": "Q04603", "name": "DPB4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR121W", "map_id": "YDR121W", "name": "DPB4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P24482", "map_id": "P24482", "name": "DPB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR175W", "map_id": "YPR175W", "name": "DPB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P21951", "map_id": "P21951", "name": "POL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL262W", "map_id": "YNL262W", "name": "POL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10778376", "map_id": "none", "name": "PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10765202", "map_id": "none", "name": "Detection of damage during initiation of DNA synthesis in S-phase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760246", "map_id": "none", "name": "DNA polymerase alpha:primase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_113656", "map_id": "none", "name": "RNA primer-DNA primer:origin duplex with DNA damage", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10767970", "map_id": "none", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10767870", "map_id": "none", "name": "SAR1B:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P20606", "map_id": "P20606", "name": "SAR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL218W", "map_id": "YPL218W", "name": "SAR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10767966", "map_id": "none", "name": "SEC23:SEC24", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38810", "map_id": "P38810", "name": "SFB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR098C", "map_id": "YHR098C", "name": "SFB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53953", "map_id": "P53953", "name": "SFB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL049C", "map_id": "YNL049C", "name": "SFB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40482", "map_id": "P40482", "name": "SEC24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL109C", "map_id": "YIL109C", "name": "SEC24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P15303", "map_id": "P15303", "name": "SEC23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR181C", "map_id": "YPR181C", "name": "SEC23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10767968", "map_id": "none", "name": "SAR1B:GTP:SEC23:SEC24", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10772440", "map_id": "none", "name": "Trimming of peptides in ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_983034", "map_id": "CHEBI:25676", "name": "oligopeptide fragment", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_983033", "map_id": "CHEBI:25676", "name": "Antigen peptide", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_8943716", "map_id": "CHEBI:59869", "name": "L-amino acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10772437", "map_id": "none", "name": "ERAP1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "P40462", "map_id": "P40462", "name": "TMA108", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL137C", "map_id": "YIL137C", "name": "TMA108", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32454", "map_id": "P32454", "name": "APE2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL157W", "map_id": "YKL157W", "name": "APE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P37898", "map_id": "P37898", "name": "AAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR047C", "map_id": "YHR047C", "name": "AAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761054", "map_id": "none", "name": "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10761046", "map_id": "none", "name": "Cyclin E:p-CDK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10761041", "map_id": "none", "name": "CCNE:CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10761051", "map_id": "P23748", "name": "MIH1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YMR036C", "map_id": "YMR036C", "name": "MIH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766479", "map_id": "none", "name": "CAK-mediated phosphorylation of Cyclin E:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760879", "map_id": "none", "name": "Cyclin E:p-T160-CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10760390", "map_id": "none", "name": "CDK and DDK associate with the Mcm10:pre-replicative complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760326", "map_id": "none", "name": "DDK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P06243", "map_id": "P06243", "name": "CDC7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL017W", "map_id": "YDL017W", "name": "CDC7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32325", "map_id": "P32325", "name": "DBF4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR052C", "map_id": "YDR052C", "name": "DBF4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10760314", "map_id": "none", "name": "CDK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10760375", "map_id": "none", "name": "MCM10:active pre-replicative complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P32354", "map_id": "P32354", "name": "MCM10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL150C", "map_id": "YIL150C", "name": "MCM10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10760377", "map_id": "none", "name": "CDK:DDK:MCM10:active pre-replicative complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10760383", "map_id": "none", "name": "DNA polymerase alpha:primase binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760277", "map_id": "none", "name": "DNA polymerase epsilon:origin complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10760279", "map_id": "none", "name": "DNA polymerase alpha:primase:DNA polymerase alpha:origin complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10760381", "map_id": "none", "name": "CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q08032", "map_id": "Q08032", "name": "CDC45", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR103C", "map_id": "YLR103C", "name": "CDC45", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761037", "map_id": "none", "name": "Formation of Cyclin E:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10760999", "map_id": "P00546", "name": "CDC28", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761033", "map_id": "none", "name": "CCNE", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10761035", "map_id": "none", "name": "CCNE:CDK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10760840", "map_id": "none", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760275", "map_id": "none", "name": "DNA polymerase epsilon", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_68419", "map_id": "none", "name": "origin of replication", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10760838", "map_id": "none", "name": "Mcm2-7 is phosphorylated by DDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760835", "map_id": "none", "name": "p-MCM2-7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10765436", "map_id": "none", "name": "Translocation of Cyclin E:Cdk2 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "reaction_10760400", "map_id": "none", "name": "Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760331", "map_id": "P32354", "name": "MCM10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760398", "map_id": "none", "name": "MCM10:pre-replicative complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10760388", "map_id": "none", "name": "Cdc45 associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760305", "map_id": "Q08032", "name": "CDC45", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760379", "map_id": "none", "name": "CDK:DDK:MCM10:active pre-replicative complex:CDC45", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10760386", "map_id": "none", "name": "DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760300", "map_id": "none", "name": "RPA1-4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10766866", "map_id": "none", "name": "Active JNK moves to the nucleus and phosphorylates different transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10765974", "map_id": "P41808", "name": "phospho-SMK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YPR054W", "map_id": "YPR054W", "name": "phospho-SMK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765931", "map_id": "P41808", "name": "phospho-SMK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10775479", "map_id": "none", "name": "KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775019", "map_id": "none", "name": "Histone H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_113560", "map_id": "CHEBI:57288", "name": "Ac-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2485002", "map_id": "CHEBI:57287", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10775464", "map_id": "none", "name": "AcK15-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10775476", "map_id": "none", "name": "KAT6:ING5:MEAF6:BRPF1,(2,3)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q08465", "map_id": "Q08465", "name": "YNG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR064C", "map_id": "YOR064C", "name": "YNG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08649", "map_id": "Q08649", "name": "phospho-ESA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR244W", "map_id": "YOR244W", "name": "phospho-ESA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P50947", "map_id": "P50947", "name": "PHO23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL097C", "map_id": "YNL097C", "name": "PHO23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38806", "map_id": "P38806", "name": "YNG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR090C", "map_id": "YHR090C", "name": "YNG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47128", "map_id": "P47128", "name": "EAF6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR082C", "map_id": "YJR082C", "name": "EAF6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775918", "map_id": "none", "name": "Type B histone acetlytransferase complex acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10763701", "map_id": "P02309", "name": "HHF2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10775881", "map_id": "P02309", "name": "HHF2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10775915", "map_id": "none", "name": "HAT1:RBBP7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q12206", "map_id": "Q12206", "name": "WTM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR229W", "map_id": "YOR229W", "name": "WTM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03010", "map_id": "Q03010", "name": "UME1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL139C", "map_id": "YPL139C", "name": "UME1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39984", "map_id": "P39984", "name": "HAT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL056W", "map_id": "YEL056W", "name": "HAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12363", "map_id": "Q12363", "name": "WTM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR230W", "map_id": "YOR230W", "name": "WTM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P13712", "map_id": "P13712", "name": "MSI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR195C", "map_id": "YBR195C", "name": "MSI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12341", "map_id": "Q12341", "name": "HAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL001W", "map_id": "YPL001W", "name": "HAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775460", "map_id": "none", "name": "ATF2 acetylates histone H2B, H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775434", "map_id": "none", "name": "Histone H2B, H4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10775457", "map_id": "none", "name": "AcK-replicative histone H2B, H4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10765915", "map_id": "none", "name": "Homologues of p-T69,T71-ATF2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P39970", "map_id": "P39970", "name": "ACA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER045C", "map_id": "YER045C", "name": "ACA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40535", "map_id": "P40535", "name": "CST6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL036W", "map_id": "YIL036W", "name": "CST6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02100", "map_id": "Q02100", "name": "SKO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL167C", "map_id": "YNL167C", "name": "SKO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775428", "map_id": "none", "name": "KAT7-containing ING4/5 complexes acetylate Me3K-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10774208", "map_id": "P36012", "name": "CSE4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10775382", "map_id": "P36012", "name": "CSE4", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10775425", "map_id": "none", "name": "KAT7:ING4,5 dimers:MEAF6:PHF17,(15,16)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764336", "map_id": "none", "name": "RNA Polymerase II CTD (phosphorylated) binds to CE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764328", "map_id": "Q01159", "name": "CEG1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YGL130W", "map_id": "YGL130W", "name": "CEG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764334", "map_id": "none", "name": "Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764330", "map_id": "none", "name": "RNA Pol II with phosphorylated CTD: CE complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q01159", "map_id": "Q01159", "name": "CEG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764381", "map_id": "none", "name": "Dissociation of transcript with 5'-GMP from GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764374", "map_id": "none", "name": "Capping complex (GpppN..)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P27692", "map_id": "P27692", "name": "phospho-SPT5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML010W", "map_id": "YML010W", "name": "phospho-SPT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32783", "map_id": "P32783", "name": "ABD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR236C", "map_id": "YBR236C", "name": "ABD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764379", "map_id": "none", "name": "Capping complex (with freed 5'- GMP)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764377", "map_id": "none", "name": "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764369", "map_id": "none", "name": "Capping complex (intermediate)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_113578", "map_id": "CHEBI:58115", "name": "GMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10764360", "map_id": "none", "name": "Capping complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_72084", "map_id": "none", "name": "nascent pre-mRNA transcript", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10764354", "map_id": "none", "name": "CE:Pol II CTD:Spt5 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_29428", "map_id": "none", "name": "DNA", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10764358", "map_id": "none", "name": "Capping complex (initial)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764365", "map_id": "none", "name": "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764362", "map_id": "none", "name": "Capping complex (hydrolyzed)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764332", "map_id": "none", "name": "Activation of GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10764386", "map_id": "none", "name": "Methylation of GMP-cap by RNA Methyltransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_77087", "map_id": "CHEBI:15414", "name": "AdoMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10762304", "map_id": "none", "name": "RNA Polymerase II (phosphorylated):TFIIF:capped pre-mRNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764383", "map_id": "none", "name": "mRNA capping factors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764352", "map_id": "P27692", "name": "phospho-SPT5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_77502", "map_id": "CHEBI:16680", "name": "AdoHcy", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10764388", "map_id": "none", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10762228", "map_id": "P34160", "name": "STO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YMR125W", "map_id": "YMR125W", "name": "STO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10762223", "map_id": "Q08920", "name": "CBC2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YPL178W", "map_id": "YPL178W", "name": "CBC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10762230", "map_id": "none", "name": "Cap Binding Complex (CBC)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P34160", "map_id": "P34160", "name": "STO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08920", "map_id": "Q08920", "name": "CBC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764356", "map_id": "none", "name": "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764346", "map_id": "P32783", "name": "ABD1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10764372", "map_id": "none", "name": "Formation of the CE:GMP intermediate complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113571", "map_id": "CHEBI:37565", "name": "GTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10764390", "map_id": "none", "name": "Recognition and binding of the mRNA cap by the cap-binding complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10762306", "map_id": "none", "name": "capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764820", "map_id": "none", "name": "Formation of Pol zeta complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764773", "map_id": "P14284", "name": "REV3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YPL167C", "map_id": "YPL167C", "name": "REV3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764778", "map_id": "P38927", "name": "REV7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YIL139C", "map_id": "YIL139C", "name": "REV7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764780", "map_id": "none", "name": "POLZ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P38927", "map_id": "P38927", "name": "REV7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P14284", "map_id": "P14284", "name": "REV3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764789", "map_id": "none", "name": "POLZ extends translesion synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764782", "map_id": "none", "name": "POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P12689", "map_id": "P12689", "name": "REV1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR346W", "map_id": "YOR346W", "name": "REV1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764786", "map_id": "none", "name": "REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt-mispairedPolydNMP)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778576", "map_id": "none", "name": "POLZ elongates POLI-incorporated dNMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778564", "map_id": "none", "name": "POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10778573", "map_id": "none", "name": "POLI:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764742", "map_id": "P12689", "name": "REV1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10778296", "map_id": "none", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764765", "map_id": "none", "name": "REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764759", "map_id": "none", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764755", "map_id": "none", "name": "MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764757", "map_id": "none", "name": "REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778567", "map_id": "none", "name": "POLI incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778558", "map_id": "none", "name": "POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778548", "map_id": "none", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778536", "map_id": "none", "name": "POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10778545", "map_id": "none", "name": "POLK:MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764768", "map_id": "none", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_30185", "map_id": "CHEBI:61481", "name": "dCTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10778539", "map_id": "none", "name": "POLK incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778530", "map_id": "none", "name": "POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10773254", "map_id": "none", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_264618", "map_id": "CHEBI:15354", "name": "Cho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1524071", "map_id": "CHEBI:36700", "name": "PCho", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773251", "map_id": "none", "name": "CHK dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P20485", "map_id": "P20485", "name": "CKI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR133W", "map_id": "YLR133W", "name": "CKI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03764", "map_id": "Q03764", "name": "EKI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR147W", "map_id": "YDR147W", "name": "EKI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773327", "map_id": "none", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_426755", "map_id": "CHEBI:16337", "name": "PA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10773324", "map_id": "none", "name": "LPIN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P32567", "map_id": "P32567", "name": "PAH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR165C", "map_id": "YMR165C", "name": "PAH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773195", "map_id": "none", "name": "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1524060", "map_id": "CHEBI:16436", "name": "CDP-Cho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_109395", "map_id": "CHEBI:60377", "name": "CMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773192", "map_id": "none", "name": "CEPT1:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P17898", "map_id": "P17898", "name": "CPT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL130C", "map_id": "YNL130C", "name": "CPT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22140", "map_id": "P22140", "name": "EPT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR123W", "map_id": "YHR123W", "name": "EPT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773296", "map_id": "none", "name": "PE is methylated to PC by PEMT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500581", "map_id": "CHEBI:16038", "name": "PE", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_71284", "map_id": "CHEBI:59789", "name": "AdoMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_71285", "map_id": "CHEBI:57856", "name": "AdoHcy", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773293", "map_id": "P05375", "name": "OPI3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YJR073C", "map_id": "YJR073C", "name": "OPI3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768148", "map_id": "none", "name": "Cho is acetylated to AcCho by CHAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_76183", "map_id": "CHEBI:57288", "name": "Ac-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_264643", "map_id": "CHEBI:15355", "name": "AcCho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10768145", "map_id": "P32796", "name": "CAT2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YML042W", "map_id": "YML042W", "name": "CAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773219", "map_id": "none", "name": "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1524057", "map_id": "CHEBI:17815", "name": "DAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_429785", "map_id": "CHEBI:16110", "name": "PC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10773216", "map_id": "none", "name": "CHPT1:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10781570", "map_id": "none", "name": "ABHD3 hydrolyses LPC(14:0) to 1AGPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5694502", "map_id": "CHEBI:64483", "name": "LPC(14:0)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1861754", "map_id": "CHEBI:33575", "name": "RCOOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5694457", "map_id": "CHEBI:11230", "name": "1AGPC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10781567", "map_id": "none", "name": "Homologues of ABHD3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q03649", "map_id": "Q03649", "name": "MGL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR210W", "map_id": "YMR210W", "name": "MGL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02891", "map_id": "Q02891", "name": "EEB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL095C", "map_id": "YPL095C", "name": "EEB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38295", "map_id": "P38295", "name": "EHT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR177C", "map_id": "YBR177C", "name": "EHT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773273", "map_id": "none", "name": "PCho and CTP are condensed to CDP-Cho by PCYT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_110614", "map_id": "CHEBI:37563", "name": "CTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10773270", "map_id": "none", "name": "PCYT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P13259", "map_id": "P13259", "name": "PCT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR202C", "map_id": "YGR202C", "name": "PCT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761101", "map_id": "none", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10761063", "map_id": "P23748", "name": "phospho-MIH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10761098", "map_id": "P39009", "name": "phospho-DUN1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YDL101C", "map_id": "YDL101C", "name": "phospho-DUN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761061", "map_id": "none", "name": "Proteolytic degradation of ubiquitinated-Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10761059", "map_id": "none", "name": "Ub-p-S123-CDC25A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P23748", "map_id": "P23748", "name": "MIH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761089", "map_id": "none", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10761086", "map_id": "none", "name": "Homologues of p-S317,S345-CHEK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P36002", "map_id": "P36002", "name": "phospho-PTK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL198C", "map_id": "YKL198C", "name": "phospho-PTK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47116", "map_id": "P47116", "name": "phospho-PTK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR059W", "map_id": "YJR059W", "name": "phospho-PTK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P06782", "map_id": "P06782", "name": "phospho-SNF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR477W", "map_id": "YDR477W", "name": "phospho-SNF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765884", "map_id": "none", "name": "G-protein alpha subunit is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_947587", "compartment_display": "cytoplasmic side of plasma membrane" }, { "id": "species_10764965", "map_id": "none", "name": "G-protein alpha:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10764864", "map_id": "P10823", "name": "GPA2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10777703", "map_id": "none", "name": "SYVN1 ubiquitinates Hh C-terminal fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10777696", "map_id": "none", "name": "C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P38307", "map_id": "P38307", "name": "DER1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR201W", "map_id": "YBR201W", "name": "DER1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05787", "map_id": "Q05787", "name": "HRD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR207W", "map_id": "YLR207W", "name": "HRD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q99220", "map_id": "Q99220", "name": "YOS9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR057W", "map_id": "YDR057W", "name": "YOS9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08109", "map_id": "Q08109", "name": "HRD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL013C", "map_id": "YOL013C", "name": "HRD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10777700", "map_id": "none", "name": "ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10777910", "map_id": "none", "name": "cAMP dissociates PKA, promoting GLI processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5263232", "compartment_display": "ciliary base" }, { "id": "species_10777906", "map_id": "none", "name": "PKA tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263232", "compartment_display": "ciliary base", "complex": "true" }, { "id": "species_10777900", "map_id": "none", "name": "PKA catalytic subunit", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263232", "compartment_display": "ciliary base", "complex": "true" }, { "id": "species_10777908", "map_id": "none", "name": "PKA regulatory subunits:cAMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263232", "compartment_display": "ciliary base", "complex": "true" }, { "id": "reaction_10768868", "map_id": "none", "name": "PEX-19 docks ABCD1/D2/D3 to peroximal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10768844", "map_id": "P28795", "name": "PEX3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "false" }, { "id": "YDR329C", "map_id": "YDR329C", "name": "PEX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768866", "map_id": "none", "name": "PEX19:ABCD1/2/3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q07418", "map_id": "Q07418", "name": "PEX19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL065C", "map_id": "YDL065C", "name": "PEX19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P34230", "map_id": "P34230", "name": "PXA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL188C", "map_id": "YKL188C", "name": "PXA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41909", "map_id": "P41909", "name": "PXA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL147W", "map_id": "YPL147W", "name": "PXA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768836", "map_id": "none", "name": "ABCD1-3 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "species_10768864", "map_id": "Q07418", "name": "PEX19", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10772903", "map_id": "none", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1454930", "map_id": "CHEBI:25696", "name": "organic anion", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1454919", "map_id": "CHEBI:25696", "name": "organic anion", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10772900", "map_id": "none", "name": "ABCCs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P0CE68", "map_id": "P0CE68", "name": "NFT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR103W", "map_id": "YKR103W", "name": "NFT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768883", "map_id": "none", "name": "HCO3- transport through ion channel", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_111627", "map_id": "CHEBI:17544", "name": "HCO3-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_425425", "map_id": "CHEBI:17544", "name": "HCO3-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10768880", "map_id": "none", "name": "Homologues of CFTR", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10786350", "map_id": "none", "name": "CFTR transits to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10786344", "map_id": "none", "name": "Homologues of misfolded CFTR", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10768816", "map_id": "none", "name": "ABC7, mABC1 and mABC2 mediate heme transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_113521", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_189444", "map_id": "CHEBI:17627", "name": "heme", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_113593", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113548", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113581", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_71185", "map_id": "CHEBI:17627", "name": "heme", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10768813", "map_id": "none", "name": "ABC7 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P40416", "map_id": "P40416", "name": "ATM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ATM1", "map_id": "ATM1", "name": "ATM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786348", "map_id": "none", "name": "misfolded CFTR is degraded by the 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10786346", "map_id": "none", "name": "Ub-misfolded nascent CFTR", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10779080", "map_id": "none", "name": "CFTR transports Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_352022", "map_id": "CHEBI:17996", "name": "Cl-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_188972", "map_id": "CHEBI:17996", "name": "Cl-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10768839", "map_id": "none", "name": "ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_382577", "map_id": "CHEBI:15904", "name": "LCFA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_382571", "map_id": "CHEBI:15904", "name": "LCFA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10789057", "map_id": "none", "name": "PM20D1 transforms oleoyl-phe from oleate and phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_351993", "map_id": "CHEBI:58095", "name": "L-Phe", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_9673048", "map_id": "CHEBI:30823", "name": "oleate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_9673044", "map_id": "CHEBI:134020", "name": "oleoyl-Phe", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10789054", "map_id": "P27614", "name": "CPS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "YJL172W", "map_id": "YJL172W", "name": "CPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789059", "map_id": "none", "name": "PM20D1 hydrolyzes oleoyl-phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10784879", "map_id": "none", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10784367", "map_id": "none", "name": "Homologues of GBF1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10784862", "map_id": "none", "name": "RAB1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "P01123", "map_id": "P01123", "name": "YPT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFL038C", "map_id": "YFL038C", "name": "YPT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784864", "map_id": "none", "name": "RAB1:GTP:GBF1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10784874", "map_id": "none", "name": "Active ARF recruits coatomer to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10784870", "map_id": "none", "name": "RAB1:GTP:GBF1:ARF:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10784438", "map_id": "none", "name": "coatomer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P43621", "map_id": "P43621", "name": "RET2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFR051C", "map_id": "YFR051C", "name": "RET2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53600", "map_id": "P53600", "name": "RET3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL010W", "map_id": "YPL010W", "name": "RET3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53622", "map_id": "P53622", "name": "COP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL145C", "map_id": "YDL145C", "name": "COP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40509", "map_id": "P40509", "name": "SEC28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL076W", "map_id": "YIL076W", "name": "SEC28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32074", "map_id": "P32074", "name": "SEC21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL287W", "map_id": "YNL287W", "name": "SEC21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41811", "map_id": "P41811", "name": "SEC27", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL137W", "map_id": "YGL137W", "name": "SEC27", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41810", "map_id": "P41810", "name": "SEC26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR238C", "map_id": "YDR238C", "name": "SEC26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784872", "map_id": "none", "name": "RAB1:GTP:GBF1:ARF:GTP:coatomer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10784939", "map_id": "none", "name": "ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10784935", "map_id": "none", "name": "Golgi-to-ER cargo", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "P18414", "map_id": "P18414", "name": "ERD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL040C", "map_id": "YBL040C", "name": "ERD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38819", "map_id": "P38819", "name": "ERP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR110W", "map_id": "YHR110W", "name": "ERP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32803", "map_id": "P32803", "name": "EMP24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL200C", "map_id": "YGL200C", "name": "EMP24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53198", "map_id": "P53198", "name": "ERP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL002W", "map_id": "YGL002W", "name": "ERP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53337", "map_id": "P53337", "name": "ERV29", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR284C", "map_id": "YGR284C", "name": "ERV29", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P54837", "map_id": "P54837", "name": "ERV25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML012W", "map_id": "YML012W", "name": "ERV25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05359", "map_id": "Q05359", "name": "ERP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAR002C-A", "map_id": "YAR002C-A", "name": "ERP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784925", "map_id": "P22214", "name": "SEC22", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "YLR268W", "map_id": "YLR268W", "name": "SEC22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784923", "map_id": "none", "name": "p24 dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "P39704", "map_id": "P39704", "name": "ERP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL007C", "map_id": "YAL007C", "name": "ERP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12403", "map_id": "Q12403", "name": "ERP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL018C", "map_id": "YDL018C", "name": "ERP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12450", "map_id": "Q12450", "name": "ERP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR016C", "map_id": "YOR016C", "name": "ERP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784463", "map_id": "none", "name": "ARFGAP1,2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32572", "map_id": "P32572", "name": "SPS18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL204C", "map_id": "YNL204C", "name": "SPS18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38682", "map_id": "P38682", "name": "GLO3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER122C", "map_id": "YER122C", "name": "GLO3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P35197", "map_id": "P35197", "name": "GCS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL226C", "map_id": "YDL226C", "name": "GCS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784937", "map_id": "none", "name": "RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "P22214", "map_id": "P22214", "name": "SEC22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784952", "map_id": "none", "name": "ARFGAPs stimulate ARF GTPase activity at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10784949", "map_id": "none", "name": "RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_432051", "compartment_display": "transport vesicle", "complex": "true" }, { "id": "species_10784385", "map_id": "none", "name": "ARF:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10784982", "map_id": "none", "name": "NSF and SNAPs bind cis-SNARE at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10769994", "map_id": "P32602", "name": "SEC17", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YBL050W", "map_id": "YBL050W", "name": "SEC17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10781444", "map_id": "none", "name": "NSF hexamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P18759", "map_id": "P18759", "name": "SEC18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR080C", "map_id": "YBR080C", "name": "SEC18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784980", "map_id": "none", "name": "SEC22B:STX18:USE1L:BNIP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P53146", "map_id": "P53146", "name": "USE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL098W", "map_id": "YGL098W", "name": "USE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P28791", "map_id": "P28791", "name": "SEC20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR498C", "map_id": "YDR498C", "name": "SEC20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41834", "map_id": "P41834", "name": "UFE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR075W", "map_id": "YOR075W", "name": "UFE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784971", "map_id": "none", "name": "SEC22B:STX18:USE1:BNIP1L:3xSNAPs:NSF hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P32602", "map_id": "P32602", "name": "SEC17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784974", "map_id": "none", "name": "NSF ATPase activity dissociates cis-SNARE at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10784957", "map_id": "P28791", "name": "SEC20", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10784962", "map_id": "P41834", "name": "UFE1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10767816", "map_id": "P22214", "name": "SEC22", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10784967", "map_id": "P53146", "name": "USE1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10784868", "map_id": "none", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10784866", "map_id": "none", "name": "RAB1:GTP:GBF1:ARF:GDP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10785080", "map_id": "none", "name": "COPI vesicle uncoating at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10785078", "map_id": "none", "name": "RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo:NBAS:RINT1:ZW10:STX18:USE1L:BNIP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P33891", "map_id": "P33891", "name": "TIP20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL145W", "map_id": "YGL145W", "name": "TIP20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53847", "map_id": "P53847", "name": "DSL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL258C", "map_id": "YNL258C", "name": "DSL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785076", "map_id": "none", "name": "Golgi-to-ER cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10785042", "map_id": "none", "name": "p24 dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10781345", "map_id": "none", "name": "RAB1:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10784877", "map_id": "none", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "reaction_10769704", "map_id": "none", "name": "SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_74113", "map_id": "CHEBI:29101", "name": "Na+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_83910", "map_id": "CHEBI:29101", "name": "Na+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10769701", "map_id": "P38329", "name": "VHC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YBR235W", "map_id": "YBR235W", "name": "VHC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769699", "map_id": "none", "name": "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_74126", "map_id": "CHEBI:29103", "name": "K+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_29804", "map_id": "CHEBI:29103", "name": "K+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10769694", "map_id": "P38329", "name": "VHC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10774613", "map_id": "none", "name": "METAP1/2 demethylates GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10774594", "map_id": "P10823", "name": "GPA2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_174390", "map_id": "CHEBI:57844", "name": "L-Met", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10774582", "map_id": "P10823", "name": "GPA2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10774610", "map_id": "none", "name": "METAP1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q01662", "map_id": "Q01662", "name": "MAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR244C", "map_id": "YLR244C", "name": "MAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38174", "map_id": "P38174", "name": "MAP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL091C", "map_id": "YBL091C", "name": "MAP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_880069", "map_id": "CHEBI:27638", "name": "Co2+", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10774654", "map_id": "none", "name": "GUCA binds Ca2+ to form GUCA:Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10774640", "map_id": "Q06389", "name": "FRQ1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "YDR373W", "map_id": "YDR373W", "name": "FRQ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10774652", "map_id": "none", "name": "GUCA:Ca2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "true" }, { "id": "Q06389", "map_id": "Q06389", "name": "FRQ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10774592", "map_id": "none", "name": "NMT1/2 transfer MYS to GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2534019", "map_id": "CHEBI:15532", "name": "MYS-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10763522", "map_id": "P10823", "name": "GPA2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "species_10774587", "map_id": "P14743", "name": "NMT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YLR195C", "map_id": "YLR195C", "name": "NMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763540", "map_id": "none", "name": "PDE6 hydrolyses cGMP to GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane" }, { "id": "species_30991", "map_id": "CHEBI:16356", "name": "cGMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10763537", "map_id": "none", "name": "GNAT1-GTP:PDE6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "true" }, { "id": "P06776", "map_id": "P06776", "name": "PDE2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR360C", "map_id": "YOR360C", "name": "PDE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10774322", "map_id": "none", "name": "atRAL is reduced to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29364", "map_id": "CHEBI:57783", "name": "NADPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_975622", "map_id": "CHEBI:17898", "name": "atRAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29366", "map_id": "CHEBI:58349", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2473607", "map_id": "CHEBI:17336", "name": "atROL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10774319", "map_id": "none", "name": "Homologues of DHRS3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74000", "compartment_display": "photoreceptor outer segment membrane", "complex": "true" }, { "id": "Q06417", "map_id": "Q06417", "name": "TDA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR426W", "map_id": "YLR426W", "name": "TDA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q07530", "map_id": "Q07530", "name": "DHRS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL114W", "map_id": "YDL114W", "name": "DHRS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03085", "map_id": "Q03085", "name": "SRL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL033C", "map_id": "YPL033C", "name": "SRL4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765352", "map_id": "none", "name": "Activation of Cdc25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765340", "map_id": "P23748", "name": "MIH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10765343", "map_id": "P23748", "name": "phospho-MIH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10765349", "map_id": "P32562", "name": "phospho-CDC5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YMR001C", "map_id": "YMR001C", "name": "CDC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765477", "map_id": "none", "name": "Inactivation of Myt1 kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765469", "map_id": "P32944", "name": "SWE1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YJL187C", "map_id": "YJL187C", "name": "phospho-SWE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765472", "map_id": "P32944", "name": "phospho-SWE1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10765474", "map_id": "P32562", "name": "phospho-CDC5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10771316", "map_id": "none", "name": "glutamine + pyruvate => 2-oxoglutaramate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_893598", "map_id": "CHEBI:30882", "name": "2OGA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10771307", "map_id": "none", "name": "PXLP-KYAT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P47039", "map_id": "P47039", "name": "BNA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL060W", "map_id": "YJL060W", "name": "BNA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781888", "map_id": "none", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_29362", "map_id": "CHEBI:57945", "name": "NADH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113529", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113590", "map_id": "CHEBI:17388", "name": "1PYR-5COOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_379717", "map_id": "CHEBI:60039", "name": "L-Pro", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10781885", "map_id": "none", "name": "PYCR2 decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P32263", "map_id": "P32263", "name": "PRO3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER023W", "map_id": "YER023W", "name": "PRO3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761570", "map_id": "none", "name": "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10761567", "map_id": "none", "name": "PYCR1 decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10761572", "map_id": "none", "name": "glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_31339", "map_id": "CHEBI:17232", "name": "L-Glu5S", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113585", "map_id": "CHEBI:15729", "name": "L-Orn", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10761557", "map_id": "none", "name": "OAT hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P07991", "map_id": "P07991", "name": "CAR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR438W", "map_id": "YLR438W", "name": "CAR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771117", "map_id": "none", "name": "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113600", "map_id": "CHEBI:16474", "name": "NADPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113563", "map_id": "CHEBI:18009", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10771114", "map_id": "none", "name": "P5CS dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P54885", "map_id": "P54885", "name": "PRO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR323C", "map_id": "YOR323C", "name": "PRO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781895", "map_id": "none", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_35305", "map_id": "CHEBI:17388", "name": "1PYR-5COOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_113538", "map_id": "CHEBI:60039", "name": "L-Pro", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10781892", "map_id": "none", "name": "PYCRL decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10761527", "map_id": "none", "name": "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_31633", "map_id": "CHEBI:28938", "name": "NH4+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761524", "map_id": "none", "name": "GLUL decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32288", "map_id": "P32288", "name": "GLN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR035W", "map_id": "YPR035W", "name": "GLN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761529", "map_id": "none", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10789049", "map_id": "none", "name": "DKC1 binds SHQ1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765537", "map_id": "P33322", "name": "CBF5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YLR175W", "map_id": "YLR175W", "name": "CBF5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10789045", "map_id": "P40486", "name": "SHQ1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YIL104C", "map_id": "YIL104C", "name": "SHQ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10789047", "map_id": "none", "name": "DKC1:SHQ1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P33322", "map_id": "P33322", "name": "CBF5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40486", "map_id": "P40486", "name": "SHQ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769750", "map_id": "none", "name": "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_427648", "map_id": "CHEBI:16189", "name": "SO4(2-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_351626", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10769747", "map_id": "none", "name": "SLC26A1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P53394", "map_id": "P53394", "name": "SLC26A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR003C", "map_id": "YPR003C", "name": "SLC26A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766300", "map_id": "none", "name": "PAPSS1,2 transfer SO4(2-) group to ATP to form APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174370", "map_id": "CHEBI:17709", "name": "APS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766269", "map_id": "Q02196", "name": "MET14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YKL001C", "map_id": "YKL001C", "name": "MET14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766274", "map_id": "none", "name": "PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_158471", "map_id": "CHEBI:58339", "name": "PAPS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10778591", "map_id": "none", "name": "KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778271", "map_id": "none", "name": "Me3K28-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776818", "map_id": "none", "name": "Me2K28-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776825", "map_id": "P14922", "name": "CYC8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YBR112C", "map_id": "YBR112C", "name": "CYC8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10778580", "map_id": "none", "name": "KDM5A-D demethylate Me3K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10777406", "map_id": "none", "name": "Me3K5-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776782", "map_id": "none", "name": "Me2K5-histone H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776810", "map_id": "none", "name": "KDM5A-D", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q03214", "map_id": "Q03214", "name": "ECM5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR176W", "map_id": "YMR176W", "name": "ECM5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47156", "map_id": "P47156", "name": "JHD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR119C", "map_id": "YJR119C", "name": "JHD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775027", "map_id": "none", "name": "KDM1A, KDM1B demethylate MeK5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775017", "map_id": "none", "name": "MeK5-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10775024", "map_id": "P50264", "name": "FMS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YMR020W", "map_id": "YMR020W", "name": "FMS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10778578", "map_id": "none", "name": "KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778230", "map_id": "none", "name": "Me2K37-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776742", "map_id": "none", "name": "MeK37-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776754", "map_id": "none", "name": "Homologues of KDM4A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q03833", "map_id": "Q03833", "name": "GIS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR096W", "map_id": "YDR096W", "name": "GIS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39956", "map_id": "P39956", "name": "RPH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER169W", "map_id": "YER169W", "name": "RPH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10778589", "map_id": "none", "name": "KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776843", "map_id": "none", "name": "Me3K10-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776759", "map_id": "none", "name": "Me2K10-histone H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776777", "map_id": "none", "name": "KDM4A, KDM4B, KDM4C, KDM4D, MINA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10776757", "map_id": "none", "name": "KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10776780", "map_id": "none", "name": "KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776761", "map_id": "none", "name": "MeK10-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10776813", "map_id": "none", "name": "KDM5A-D demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10778593", "map_id": "none", "name": "KDM1A, KDM1B demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10776830", "map_id": "none", "name": "KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776823", "map_id": "none", "name": "MeK28-histone H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10770574", "map_id": "none", "name": "Phosphorylation of MEF2 proteins by p38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10770541", "map_id": "none", "name": "MEF2 proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P38128", "map_id": "P38128", "name": "phospho-SMP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR182C", "map_id": "YBR182C", "name": "phospho-SMP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12224", "map_id": "Q12224", "name": "phospho-RLM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL089C", "map_id": "YPL089C", "name": "phospho-RLM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10770545", "map_id": "none", "name": "phospho-p38 alpha/beta/gamma MAPK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P32485", "map_id": "P32485", "name": "phospho-HOG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10770571", "map_id": "none", "name": "phospho p38:phospho MEF2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10769182", "map_id": "none", "name": "Transport of L1 into endosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17940", "compartment_display": "endosome" }, { "id": "species_10769180", "map_id": "none", "name": "L1:AP-2 Clathrin complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20592", "compartment_display": "clathrin-coated endocytic vesicle", "complex": "true" }, { "id": "P17891", "map_id": "P17891", "name": "CLC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR167W", "map_id": "YGR167W", "name": "CLC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36000", "map_id": "P36000", "name": "APL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL135C", "map_id": "YKL135C", "name": "APL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38065", "map_id": "P38065", "name": "APL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL037W", "map_id": "YBL037W", "name": "APL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P27351", "map_id": "P27351", "name": "APL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR005W", "map_id": "YJR005W", "name": "APL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q99186", "map_id": "Q99186", "name": "APM4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL062C", "map_id": "YOL062C", "name": "APM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q00381", "map_id": "Q00381", "name": "APS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR058C", "map_id": "YJR058C", "name": "APS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770284", "map_id": "none", "name": "Phosphorylation of L1 by ERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764614", "map_id": "P16892", "name": "phospho-FUS3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YBL016W", "map_id": "YBL016W", "name": "FUS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10770282", "map_id": "none", "name": "pL1 (S1204, 1248):ERK2:clathrin-dynamin complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17940", "compartment_display": "endosome", "complex": "true" }, { "id": "P16892", "map_id": "P16892", "name": "FUS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764609", "map_id": "none", "name": "MAP2K1 phosphorylates MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764572", "map_id": "none", "name": "p-2S-MAP2K1:MAPK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P06784", "map_id": "P06784", "name": "phospho-STE7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL159W", "map_id": "YDL159W", "name": "phospho-STE7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q00772", "map_id": "Q00772", "name": "SLT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR030C", "map_id": "YHR030C", "name": "SLT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P14681", "map_id": "P14681", "name": "KSS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR040W", "map_id": "YGR040W", "name": "KSS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764600", "map_id": "none", "name": "p-T,Y-MAPK3:p-2S-MAP2K1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10764605", "map_id": "P06784", "name": "phospho-STE7", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10767247", "map_id": "none", "name": "ERK1/2 phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10767221", "map_id": "P38070", "name": "YPK3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YBR028C", "map_id": "YBR028C", "name": "YPK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10767227", "map_id": "P38070", "name": "phospho-YPK3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10767244", "map_id": "none", "name": "p-T,Y MAPK dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764619", "map_id": "none", "name": "MAP2K2 phosphorylates MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764582", "map_id": "none", "name": "p-S,T-MAP2K2:MAPK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10764616", "map_id": "none", "name": "p-S,T-MAP2K2:p-T,Y-MAPK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10766423", "map_id": "none", "name": "Formation of GINS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10766419", "map_id": "Q03406", "name": "SLD5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YDR489W", "map_id": "YDR489W", "name": "SLD5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10766414", "map_id": "Q12146", "name": "PSF3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YOL146W", "map_id": "YOL146W", "name": "PSF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10766404", "map_id": "Q12488", "name": "PSF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YDR013W", "map_id": "YDR013W", "name": "PSF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10766409", "map_id": "P40359", "name": "PSF2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YJL072C", "map_id": "YJL072C", "name": "PSF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10766421", "map_id": "none", "name": "GINS complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q12488", "map_id": "Q12488", "name": "PSF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03406", "map_id": "Q03406", "name": "SLD5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40359", "map_id": "P40359", "name": "PSF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12146", "map_id": "Q12146", "name": "PSF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787208", "map_id": "none", "name": "UGT1A10 transfers GlcA from UDP-GlcA to GCTN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8941723", "map_id": "CHEBI:34778", "name": "GCTN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_8941725", "map_id": "CHEBI:133667", "name": "GCTN4OG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10765445", "map_id": "Q06321", "name": "ATG26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10772692", "map_id": "none", "name": "CNDP2:2Mn2+ dimer hydrolyses CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1247904", "map_id": "CHEBI:4047", "name": "CysGly", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10788717", "map_id": "none", "name": "UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_159160", "map_id": "CHEBI:16427", "name": "BMG", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_159149", "map_id": "CHEBI:18392", "name": "BDG", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10788714", "map_id": "none", "name": "UGT1A1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q06321", "map_id": "Q06321", "name": "ATG26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765464", "map_id": "none", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_159151", "map_id": "CHEBI:16990", "name": "BIL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10765459", "map_id": "Q06321", "name": "ATG26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10766342", "map_id": "none", "name": "Formation of N-glucuronides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_174932", "map_id": "none", "name": "N-centre functional group substrate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "CHEBI:41774", "map_id": "CHEBI:41774", "name": "CHEBI:41774", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17688", "map_id": "CHEBI:17688", "name": "CHEBI:17688", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_174918", "map_id": "none", "name": "N-glucuronide", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "CHEBI:32663", "map_id": "CHEBI:32663", "name": "CHEBI:32663", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:63860", "map_id": "CHEBI:63860", "name": "CHEBI:63860", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766297", "map_id": "none", "name": "MAT1A multimers transfer Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10766294", "map_id": "none", "name": "MAT1A multimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P19358", "map_id": "P19358", "name": "SAM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR502C", "map_id": "YDR502C", "name": "SAM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P10659", "map_id": "P10659", "name": "SAM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR180W", "map_id": "YLR180W", "name": "SAM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765462", "map_id": "none", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "reaction_10766310", "map_id": "none", "name": "GSS:Mg2+ dimer synthesizes GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174393", "map_id": "CHEBI:17515", "name": "gGluCys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29450", "map_id": "CHEBI:57925", "name": "GSH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766307", "map_id": "none", "name": "GSS:Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08220", "map_id": "Q08220", "name": "GSH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL049W", "map_id": "YOL049W", "name": "GSH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766322", "map_id": "none", "name": "AHCY:NAD+ tetramer hydrolyses AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_83909", "map_id": "CHEBI:16335", "name": "Ade-Rib", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10766319", "map_id": "none", "name": "AHCY:NAD+ tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P39954", "map_id": "P39954", "name": "SAH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER043C", "map_id": "YER043C", "name": "SAH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787391", "map_id": "none", "name": "GGT dimers hydrolyse GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1247892", "map_id": "CHEBI:16856", "name": "GSH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_210382", "map_id": "CHEBI:29985", "name": "L-Glu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_1247934", "map_id": "CHEBI:4047", "name": "CysGly", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10781250", "map_id": "none", "name": "ESD dimer hydrolyses S-FGSH to GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_113519", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_5693723", "map_id": "CHEBI:16225", "name": "S-FGSH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_158543", "map_id": "CHEBI:16856", "name": "GSH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_194712", "map_id": "CHEBI:30751", "name": "formate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10781247", "map_id": "none", "name": "ESD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "P40363", "map_id": "P40363", "name": "ESD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL068C", "map_id": "YJL068C", "name": "ESD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10783821", "map_id": "none", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6806829", "map_id": "CHEBI:17826", "name": "MMAIII", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6800127", "map_id": "CHEBI:48765", "name": "DMAA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10783815", "map_id": "none", "name": "N6AMT1:TRMT112", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P53738", "map_id": "P53738", "name": "TRM112", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "TRM112", "map_id": "TRM112", "name": "TRM112", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03920", "map_id": "Q03920", "name": "MTQ2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR140W", "map_id": "YDR140W", "name": "MTQ2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772702", "map_id": "none", "name": "OPLAH hydrolyses OPRO to L-Glu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1247942", "map_id": "CHEBI:18183", "name": "OPRO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772699", "map_id": "none", "name": "OPLAH", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P28273", "map_id": "P28273", "name": "OXP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL215C", "map_id": "YKL215C", "name": "OXP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10788719", "map_id": "none", "name": "UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "reaction_10761138", "map_id": "none", "name": "UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29494", "map_id": "CHEBI:46398", "name": "UTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29548", "map_id": "CHEBI:16077", "name": "G1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29410", "map_id": "CHEBI:18066", "name": "UDP-Glc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761135", "map_id": "none", "name": "8xUGP2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32861", "map_id": "P32861", "name": "UGP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL035W", "map_id": "YKL035W", "name": "UGP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781969", "map_id": "none", "name": "CHAC1,2 cleaves GSH to OPRO and CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10781964", "map_id": "P32656", "name": "GCG1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YER163C", "map_id": "YER163C", "name": "GCG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10778676", "map_id": "none", "name": "NIK autophosphorylates on T559", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778673", "map_id": "P25390", "name": "phospho-SSK22", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10778670", "map_id": "none", "name": "26Sproteasome degrades K48polyUb-NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778668", "map_id": "P25390", "name": "SSK22", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10784295", "map_id": "none", "name": "Release of SEPT4 from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10784279", "map_id": "none", "name": "Homologues of SEPT4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "P32457", "map_id": "P32457", "name": "CDC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR314C", "map_id": "YLR314C", "name": "CDC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q07657", "map_id": "Q07657", "name": "SHS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL225W", "map_id": "YDL225W", "name": "SHS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04921", "map_id": "Q04921", "name": "SPR28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR218C", "map_id": "YDR218C", "name": "SPR28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32468", "map_id": "P32468", "name": "CDC12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR107C", "map_id": "YHR107C", "name": "CDC12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41901", "map_id": "P41901", "name": "SPR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR059W", "map_id": "YGR059W", "name": "SPR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32458", "map_id": "P32458", "name": "CDC11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR076C", "map_id": "YJR076C", "name": "CDC11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784293", "map_id": "none", "name": "Homologues of SEPT4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10765222", "map_id": "none", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10765220", "map_id": "none", "name": "Homologues of CYCS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "P00045", "map_id": "P00045", "name": "CYC7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL039C", "map_id": "YEL039C", "name": "CYC7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00044", "map_id": "P00044", "name": "CYC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR048W", "map_id": "YJR048W", "name": "CYC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765214", "map_id": "none", "name": "Homologues of CYCS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10764147", "map_id": "none", "name": "Abortive Initiation After Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764145", "map_id": "none", "name": "pol II transcription complex containing 4-9 nucleotide long transcript", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_75897", "map_id": "none", "name": "template DNA:4-9 nucleotide transcript hybrid", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10764072", "map_id": "none", "name": "Fall Back to Closed Pre-initiation Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10765186", "map_id": "none", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764976", "map_id": "P32914", "name": "SPT4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YGR063C", "map_id": "YGR063C", "name": "SPT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764978", "map_id": "none", "name": "DSIF complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P32914", "map_id": "P32914", "name": "SPT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765190", "map_id": "none", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765001", "map_id": "none", "name": "DSIF:NELF:early elongation complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q03254", "map_id": "Q03254", "name": "FCP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR277W", "map_id": "YMR277W", "name": "FCP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763507", "map_id": "none", "name": "Abortive initiation after formation of the first phosphodiester bond", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_109877", "map_id": "none", "name": "template DNA with first transcript dinucleotide, opened to +8 position", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10764060", "map_id": "none", "name": "Abortive Initiation Before Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764058", "map_id": "none", "name": "Pol II Promoter Escape Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110068", "map_id": "none", "name": "DNA containing Pol II promoter with transcript with 2 or 3 nucleotides", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10765192", "map_id": "none", "name": "2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765164", "map_id": "none", "name": "Processive elongation complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q02793", "map_id": "Q02793", "name": "SKI8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SKI8", "map_id": "SKI8", "name": "SKI8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32558", "map_id": "P32558", "name": "SPT16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL207W", "map_id": "YGL207W", "name": "SPT16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03957", "map_id": "Q03957", "name": "CTK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL139W", "map_id": "YKL139W", "name": "CTK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53064", "map_id": "P53064", "name": "RTF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL244W", "map_id": "YGL244W", "name": "RTF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38439", "map_id": "P38439", "name": "LEO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR123C", "map_id": "YOR123C", "name": "LEO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P35189", "map_id": "P35189", "name": "TAF14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL129W", "map_id": "YPL129W", "name": "TAF14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P23615", "map_id": "P23615", "name": "SPT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR116W", "map_id": "YGR116W", "name": "SPT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05949", "map_id": "Q05949", "name": "BUR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR226W", "map_id": "YLR226W", "name": "BUR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P89105", "map_id": "P89105", "name": "CTR9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL145C", "map_id": "YOL145C", "name": "CTR9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P07273", "map_id": "P07273", "name": "DST1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL043W", "map_id": "YGL043W", "name": "DST1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38351", "map_id": "P38351", "name": "PAF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR279W", "map_id": "YBR279W", "name": "PAF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53930", "map_id": "P53930", "name": "YAF9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL107W", "map_id": "YNL107W", "name": "YAF9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53861", "map_id": "P53861", "name": "ELA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL230C", "map_id": "YNL230C", "name": "ELA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q99314", "map_id": "Q99314", "name": "SAS5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR213C", "map_id": "YOR213C", "name": "SAS5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06697", "map_id": "Q06697", "name": "CDC73", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR418C", "map_id": "YLR418C", "name": "CDC73", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03071", "map_id": "Q03071", "name": "ELC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL046C", "map_id": "YPL046C", "name": "ELC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36106", "map_id": "P36106", "name": "BYE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL005C", "map_id": "YKL005C", "name": "BYE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04636", "map_id": "Q04636", "name": "POB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML069W", "map_id": "YML069W", "name": "POB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06505", "map_id": "Q06505", "name": "SPN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR133C", "map_id": "YPR133C", "name": "SPN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P46962", "map_id": "P46962", "name": "CTK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL006C", "map_id": "YJL006C", "name": "CTK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765168", "map_id": "none", "name": "Paused processive elongation complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10765184", "map_id": "none", "name": "Formation of P-TEFb complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765028", "map_id": "none", "name": "CCNT1,CCNT2,CCNK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10765006", "map_id": "Q03957", "name": "CTK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10765030", "map_id": "none", "name": "P-TEFb complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10765170", "map_id": "none", "name": "Resumption of elongation after recovery from pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10765198", "map_id": "none", "name": "7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10765182", "map_id": "none", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765097", "map_id": "P32558", "name": "SPT16", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10765092", "map_id": "Q04636", "name": "POB3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10765099", "map_id": "none", "name": "FACT complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10765174", "map_id": "none", "name": "Abortive termination of elongation after arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765172", "map_id": "none", "name": "Aborted elongation complex after arrest", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10765196", "map_id": "none", "name": "TFIIS-mediated recovery of elongation from arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10761589", "map_id": "none", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29498", "map_id": "CHEBI:15729", "name": "L-Orn", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29610", "map_id": "CHEBI:17148", "name": "Putrescine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761586", "map_id": "P08432", "name": "SPE1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YKL184W", "map_id": "YKL184W", "name": "SPE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768335", "map_id": "none", "name": "Arginine<=>Agmatine+CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29468", "map_id": "CHEBI:32682", "name": "L-Arg", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_351164", "map_id": "CHEBI:17431", "name": "AGM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10768332", "map_id": "P08432", "name": "SPE1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10768411", "map_id": "none", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353113", "map_id": "CHEBI:15625", "name": "dc-AdoMet", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_204635", "map_id": "CHEBI:16610", "name": "SPM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10768408", "map_id": "Q12074", "name": "SPE3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YPR069C", "map_id": "YPR069C", "name": "SPE3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768403", "map_id": "none", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353555", "map_id": "CHEBI:17927", "name": "NASPM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10768398", "map_id": "none", "name": "Homologues of SAT1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q06592", "map_id": "Q06592", "name": "HPA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR193C", "map_id": "YPR193C", "name": "HPA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39979", "map_id": "P39979", "name": "HPA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL066W", "map_id": "YEL066W", "name": "HPA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768419", "map_id": "none", "name": "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768416", "map_id": "P21182", "name": "SPE2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YOL052C", "map_id": "YOL052C", "name": "SPE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768401", "map_id": "none", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353560", "map_id": "CHEBI:15746", "name": "SPN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_353575", "map_id": "CHEBI:17312", "name": "NASPN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10778699", "map_id": "none", "name": "p-T774-PKN1 binds CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778027", "map_id": "P24583", "name": "phospho-PKC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10778697", "map_id": "none", "name": "p-T774-PKN1:CDC25C", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10778693", "map_id": "none", "name": "PAK2 phosphorylates myosin regulatory light chain (MRLC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778684", "map_id": "none", "name": "Smooth muscle/non-muscle myosin II", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P08964", "map_id": "P08964", "name": "MYO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR023W", "map_id": "YHR023W", "name": "MYO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06580", "map_id": "Q06580", "name": "phospho-MLC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR188C", "map_id": "YPR188C", "name": "phospho-MLC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53141", "map_id": "P53141", "name": "MLC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL106W", "map_id": "YGL106W", "name": "MLC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10778690", "map_id": "none", "name": "p-T19-MRLC-Smooth muscle/non-muscle myosin II", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10778151", "map_id": "none", "name": "Homologues of p-S141,T402-PAK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10778117", "map_id": "none", "name": "GTP-bound RAC1 and CDC42 bind IQGAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778113", "map_id": "none", "name": "IQGAP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10778115", "map_id": "none", "name": "RAC1,CDC42:GTP:IQGAPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10778702", "map_id": "none", "name": "p-T774-PKN1 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10763798", "map_id": "P23748", "name": "phospho-MIH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10778091", "map_id": "none", "name": "KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778076", "map_id": "none", "name": "p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_193079", "map_id": "CHEBI:16422", "name": "ANDST", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193057", "map_id": "CHEBI:17347", "name": "TEST", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_469662", "map_id": "CHEBI:16330", "name": "DHTEST", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:29117", "map_id": "CHEBI:29117", "name": "CHEBI:29117", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776769", "map_id": "none", "name": "Homologues of KDM4C", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10778088", "map_id": "none", "name": "p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778074", "map_id": "none", "name": "PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778057", "map_id": "none", "name": "p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10778071", "map_id": "none", "name": "p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778123", "map_id": "none", "name": "IQGAPs bind F-actin, which is inhibited by calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10773881", "map_id": "none", "name": "F-actin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10778119", "map_id": "none", "name": "RAC1,CDC42:GTP:IQGAP:F-actin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10778121", "map_id": "none", "name": "RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10778078", "map_id": "none", "name": "Demethylase KDM4C binds KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10787831", "map_id": "none", "name": "RAC1 and CDC42 activate PAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768988", "map_id": "none", "name": "PAK2 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10768986", "map_id": "none", "name": "Homologues of PAK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10778133", "map_id": "none", "name": "CDC42:GTP,RAC1:GTP:PAK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10778020", "map_id": "none", "name": "RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10778012", "map_id": "P24583", "name": "PKC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10769305", "map_id": "none", "name": "RHOA/B/C:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10778018", "map_id": "none", "name": "RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10778160", "map_id": "none", "name": "Autophosphorylation of PAK1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778137", "map_id": "none", "name": "CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10778157", "map_id": "none", "name": "p-S,T-PAK1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10774032", "map_id": "none", "name": "RAC1 and CDC42 activate PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768972", "map_id": "none", "name": "PAK1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10768970", "map_id": "Q03497", "name": "STE20", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10774023", "map_id": "none", "name": "RAC1:GTP,CDC42:GTP:PAK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10787829", "map_id": "none", "name": "RAC1 and CDC42 activate PAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768992", "map_id": "none", "name": "PAK3 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10768990", "map_id": "Q03497", "name": "STE20", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10778135", "map_id": "none", "name": "CDC42:GTP,RAC1:GTP:PAK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10778126", "map_id": "none", "name": "IQGAPs bind CALM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10767596", "map_id": "none", "name": "CALM1:4Ca2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788712", "map_id": "none", "name": "PKC phosphorylates NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788701", "map_id": "none", "name": "PIN1:p-S-345-NCF1:NCF2:NCF4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P29366", "map_id": "P29366", "name": "phospho-BEM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR200W", "map_id": "YBR200W", "name": "phospho-BEM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22696", "map_id": "P22696", "name": "ESS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR017C", "map_id": "YJR017C", "name": "ESS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788710", "map_id": "none", "name": "PIN1:p-S-6S-NCF1:NCF2:NCF4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10777257", "map_id": "P24583", "name": "phospho-PKC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10774058", "map_id": "none", "name": "Branching and elongation of mother and daughter filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10774056", "map_id": "none", "name": "Mother filament:ARP2/3:actin:ADP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P40518", "map_id": "P40518", "name": "ARC15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL062C", "map_id": "YIL062C", "name": "ARC15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53731", "map_id": "P53731", "name": "ARC35", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNR035C", "map_id": "YNR035C", "name": "ARC35", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P33204", "map_id": "P33204", "name": "ARC19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL013C", "map_id": "YKL013C", "name": "ARC19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32381", "map_id": "P32381", "name": "ARP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL029W", "map_id": "YDL029W", "name": "ARP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47117", "map_id": "P47117", "name": "ARP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR065C", "map_id": "YJR065C", "name": "ARP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38328", "map_id": "P38328", "name": "ARC40", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR234C", "map_id": "YBR234C", "name": "ARC40", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05933", "map_id": "Q05933", "name": "ARC18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR370C", "map_id": "YLR370C", "name": "ARC18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10767714", "map_id": "none", "name": "G-actin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10773926", "map_id": "none", "name": "Mother filament:branching complex:daughter filament", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10778036", "map_id": "none", "name": "PDPK1 phosphorylates PKN1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778022", "map_id": "none", "name": "RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10782731", "map_id": "none", "name": "PIK3C3:PIK3R4 phosphorylates PI to PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane" }, { "id": "species_1524165", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629751", "map_id": "CHEBI:17283", "name": "PI3P", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10782728", "map_id": "none", "name": "PIK3C3:PIK3R4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "P22543", "map_id": "P22543", "name": "VPS34", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR240W", "map_id": "YLR240W", "name": "VPS34", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22219", "map_id": "P22219", "name": "VPS15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR097W", "map_id": "YBR097W", "name": "VPS15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10778024", "map_id": "none", "name": "RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10767642", "map_id": "none", "name": "eNOS synthesizes NO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_202124", "map_id": "CHEBI:16480", "name": "NO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29968", "map_id": "CHEBI:16349", "name": "L-Cit", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10767639", "map_id": "none", "name": "p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P12688", "map_id": "P12688", "name": "phospho-YPK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL126W", "map_id": "YKL126W", "name": "phospho-YPK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P02829", "map_id": "P02829", "name": "HSP82", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL240C", "map_id": "YPL240C", "name": "HSP82", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P16603", "map_id": "P16603", "name": "NCP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR042W", "map_id": "YHR042W", "name": "NCP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P15108", "map_id": "P15108", "name": "HSC82", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR186W", "map_id": "YMR186W", "name": "HSC82", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29870", "map_id": "CHEBI:15372", "name": "BH4", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_113596", "map_id": "CHEBI:16238", "name": "FAD", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "P11792", "map_id": "P11792", "name": "phospho-SCH9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR205W", "map_id": "YHR205W", "name": "phospho-SCH9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5693375", "map_id": "CHEBI:25682", "name": "ADMA", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10777290", "map_id": "none", "name": "PDK1 phosphorylates PKC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10764513", "map_id": "Q12236", "name": "PKH2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10777285", "map_id": "none", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10777268", "map_id": "P24583", "name": "phospho-PKC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10777283", "map_id": "none", "name": "DAG:active PKC:Ca+2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10774274", "map_id": "none", "name": "AKT binds PDPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10767085", "map_id": "none", "name": "p-S-AKT:PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10767087", "map_id": "none", "name": "p-S-AKT:PDPK1:PIP3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10777281", "map_id": "none", "name": "PKC autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10767108", "map_id": "none", "name": "PDPK1 phosphorylates AKT at T308", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767105", "map_id": "none", "name": "p-T,p-S-AKT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10766460", "map_id": "none", "name": "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10766440", "map_id": "P36003", "name": "NNK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YKL171W", "map_id": "YKL171W", "name": "phospho-NNK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10766447", "map_id": "P36003", "name": "phospho-NNK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766457", "map_id": "none", "name": "Phospho-MAP kinase p38 (Mg2+ cofactor)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10767654", "map_id": "none", "name": "AKT1 binds eNOS complex via HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767610", "map_id": "none", "name": "eNOS:CaM:HSP90", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10767095", "map_id": "none", "name": "Homologues of p-T308,S473-AKT1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10767618", "map_id": "none", "name": "eNOS:CaM:HSP90:p-AKT1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10777296", "map_id": "none", "name": "PKC phosphorylates sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10769088", "map_id": "Q06147", "name": "LCB5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YLR260W", "map_id": "YLR260W", "name": "LCB5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10777293", "map_id": "Q06147", "name": "phospho-LCB5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773346", "map_id": "none", "name": "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767635", "map_id": "none", "name": "p-S1177-eNOS:CaM:HSP90:p-AKT1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10767637", "map_id": "none", "name": "AKT1 phosphorylates eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10767219", "map_id": "none", "name": "TORC2 (mTOR) phosphorylates AKT at S473", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767182", "map_id": "none", "name": "AKT:PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10767216", "map_id": "none", "name": "TORC2 complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08236", "map_id": "Q08236", "name": "AVO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL078W", "map_id": "YOL078W", "name": "AVO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32600", "map_id": "P32600", "name": "TOR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL203C", "map_id": "YKL203C", "name": "TOR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41318", "map_id": "P41318", "name": "LST8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL006W", "map_id": "YNL006W", "name": "LST8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40061", "map_id": "P40061", "name": "TSC11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER093C", "map_id": "YER093C", "name": "TSC11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38346", "map_id": "P38346", "name": "BIT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR270C", "map_id": "YBR270C", "name": "BIT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47041", "map_id": "P47041", "name": "BIT61", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL058C", "map_id": "YJL058C", "name": "BIT61", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772766", "map_id": "none", "name": "Activation of TASK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10772763", "map_id": "none", "name": "TASK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P40310", "map_id": "P40310", "name": "TOK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL093C", "map_id": "YJL093C", "name": "TOK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766256", "map_id": "none", "name": "Dephosphorylation of phospho-Cdh1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10766246", "map_id": "P53197", "name": "phospho-CDH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YGL003C", "map_id": "YGL003C", "name": "CDH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10766234", "map_id": "P53197", "name": "CDH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766253", "map_id": "none", "name": "phospho-Cdh1 phosphatase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q00684", "map_id": "Q00684", "name": "CDC14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFR028C", "map_id": "YFR028C", "name": "CDC14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769735", "map_id": "none", "name": "eNoSC deacetylates histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10769718", "map_id": "none", "name": "Chromatin with acetylated H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_427523", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10768101", "map_id": "none", "name": "Chromatin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_427498", "map_id": "CHEBI:76279", "name": "2'-O-acetyl-ADP-ribose", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_427497", "map_id": "CHEBI:17154", "name": "NAM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10769732", "map_id": "none", "name": "eNoSC", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P06700", "map_id": "P06700", "name": "SIR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL042C", "map_id": "YDL042C", "name": "SIR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38961", "map_id": "P38961", "name": "RRP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR083W", "map_id": "YDR083W", "name": "RRP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769738", "map_id": "none", "name": "eNoSC dimethylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10763784", "map_id": "none", "name": "Chromatin (H3K9me2)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10765828", "map_id": "none", "name": "ADP and Pi bind to ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10765816", "map_id": "none", "name": "F1Fo ATP synthase", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P24814", "map_id": "P24814", "name": "GRR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR090C", "map_id": "YJR090C", "name": "GRR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00854", "map_id": "P00854", "name": "ATP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0085", "map_id": "Q0085", "name": "ATP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00830", "map_id": "P00830", "name": "ATP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ATP2", "map_id": "ATP2", "name": "ATP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P30902", "map_id": "P30902", "name": "ATP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL016C", "map_id": "YKL016C", "name": "ATP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P61829", "map_id": "P61829", "name": "OLI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "OLI1", "map_id": "OLI1", "name": "OLI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P05626", "map_id": "P05626", "name": "ATP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL078C", "map_id": "YPL078C", "name": "ATP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P21306", "map_id": "P21306", "name": "ATP15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL271W", "map_id": "YPL271W", "name": "ATP15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12165", "map_id": "Q12165", "name": "ATP16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL004W", "map_id": "YDL004W", "name": "ATP16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P09457", "map_id": "P09457", "name": "ATP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR298C", "map_id": "YDR298C", "name": "ATP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38077", "map_id": "P38077", "name": "ATP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR039W", "map_id": "YBR039W", "name": "ATP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P07251", "map_id": "P07251", "name": "ATP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ATP1", "map_id": "ATP1", "name": "ATP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12233", "map_id": "Q12233", "name": "ATP20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR020W", "map_id": "YPR020W", "name": "ATP20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765818", "map_id": "none", "name": "ATPase:ADP:Pi", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10765823", "map_id": "none", "name": "ATPase synthesizes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10765820", "map_id": "none", "name": "ATPase:ATP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10765826", "map_id": "none", "name": "Enzyme-bound ATP is released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_163953", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "reaction_10783791", "map_id": "none", "name": "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6799540", "map_id": "CHEBI:91284", "name": "alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_429579", "map_id": "CHEBI:4208", "name": "Man", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6799543", "map_id": "CHEBI:91280", "name": "alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10783788", "map_id": "none", "name": "MAN2C1:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P22855", "map_id": "P22855", "name": "AMS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL156W", "map_id": "YGL156W", "name": "AMS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765881", "map_id": "none", "name": "Phosphorylation and activation of eIF4G by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762672", "map_id": "none", "name": "Homologues of EIF4G1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P39936", "map_id": "P39936", "name": "TIF4632", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL049C", "map_id": "YGL049C", "name": "TIF4632", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39935", "map_id": "P39935", "name": "TIF4631", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR162W", "map_id": "YGR162W", "name": "TIF4631", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765879", "map_id": "none", "name": "Homologues of p-S1108,S1148,S1192-EIF4G1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10765848", "map_id": "P38070", "name": "phospho-YPK3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10765867", "map_id": "none", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762517", "map_id": "none", "name": "Homologues of RPS6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10765864", "map_id": "none", "name": "Homologues of p-5S-RPS6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10789075", "map_id": "none", "name": "FKBP1A binds sirolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9678687", "map_id": "LigandDisplayForward?ligandId=6031", "name": "sirolimus", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10789071", "map_id": "P20081", "name": "FPR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YNL135C", "map_id": "YNL135C", "name": "FPR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10789073", "map_id": "none", "name": "FKBP1A:sirolimus", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P20081", "map_id": "P20081", "name": "FPR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770295", "map_id": "none", "name": "Aquaporin-3 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10770292", "map_id": "none", "name": "AQP3 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P23900", "map_id": "P23900", "name": "FPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLL043W", "map_id": "YLL043W", "name": "FPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P43549", "map_id": "P43549", "name": "AQY3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFL054C", "map_id": "YFL054C", "name": "AQY3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789035", "map_id": "none", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10789031", "map_id": "none", "name": "LEM2D:ESCRT-III:IST1:CC2D1B:SPAST", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "P36095", "map_id": "P36095", "name": "VPS24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL041W", "map_id": "YKL041W", "name": "VPS24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39929", "map_id": "P39929", "name": "SNF7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR025W", "map_id": "YLR025W", "name": "SNF7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03390", "map_id": "Q03390", "name": "VPS60", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR486C", "map_id": "YDR486C", "name": "VPS60", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36108", "map_id": "P36108", "name": "DID4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL002W", "map_id": "YKL002W", "name": "DID4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39955", "map_id": "P39955", "name": "SAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER047C", "map_id": "YER047C", "name": "SAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04272", "map_id": "Q04272", "name": "VPS20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR077C", "map_id": "YMR077C", "name": "VPS20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53843", "map_id": "P53843", "name": "IST1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL265C", "map_id": "YNL265C", "name": "IST1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10771525", "map_id": "P52917", "name": "VPS4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YPR173C", "map_id": "YPR173C", "name": "VPS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10789033", "map_id": "none", "name": "LEM2D:ESCRT-III:IST1:CC2D1B:SPAST:VPS4A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "P52917", "map_id": "P52917", "name": "VPS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789037", "map_id": "none", "name": "SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10789019", "map_id": "P39955", "name": "SAP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10789029", "map_id": "none", "name": "LEM2D:ESCRT-III:IST1:CC2D1B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10789040", "map_id": "none", "name": "SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768744", "map_id": "none", "name": "Microtubule", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P02557", "map_id": "P02557", "name": "TUB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFL037W", "map_id": "YFL037W", "name": "TUB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768740", "map_id": "none", "name": "alpha-beta tubulin dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10786014", "map_id": "none", "name": "VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10786004", "map_id": "none", "name": "VLDL:PCSK9:Clathrin:AP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P09232", "map_id": "P09232", "name": "PRB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL060C", "map_id": "YEL060C", "name": "PRB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10786012", "map_id": "none", "name": "VLDL:PCSK9:Clathrin:AP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10781954", "map_id": "none", "name": "Degradation of PCSK9:LDLR:Clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1660541", "compartment_display": "endolysosome membrane" }, { "id": "species_10781950", "map_id": "none", "name": "PCSK9:LDLR:Clathrin:AP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1660541", "compartment_display": "endolysosome membrane", "complex": "true" }, { "id": "species_10781948", "map_id": "none", "name": "Clathrin:AP2 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24339", "compartment_display": "clathrin-coated endocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10785158", "map_id": "none", "name": "NCEH1 hydrolyzes cholesterol esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_163579", "map_id": "CHEBI:17002", "name": "CHEST", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_216762", "map_id": "CHEBI:16113", "name": "CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane", "complex": "false" }, { "id": "species_8876730", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10785155", "map_id": "P53324", "name": "SAY1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YGR263C", "map_id": "YGR263C", "name": "SAY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768163", "map_id": "none", "name": "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_194276", "map_id": "CHEBI:16110", "name": "phosphatidylcholines", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_171149", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_194236", "map_id": "CHEBI:17504", "name": "1-acyl LPC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_171076", "map_id": "CHEBI:17002", "name": "CHEST", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10768160", "map_id": "none", "name": "Homologues of LCAT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P47139", "map_id": "P47139", "name": "LCAT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR098C", "map_id": "YJR098C", "name": "LCAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P54857", "map_id": "P54857", "name": "TGL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR058C", "map_id": "YDR058C", "name": "TGL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786892", "map_id": "none", "name": "CHOL translocates from lysosome membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10786890", "map_id": "none", "name": "NPC1:CHOL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "Q12200", "map_id": "Q12200", "name": "NCR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL006W", "map_id": "YPL006W", "name": "NCR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_171095", "map_id": "CHEBI:16113", "name": "CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_193384", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10786888", "map_id": "Q12200", "name": "NCR1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "reaction_10781952", "map_id": "none", "name": "PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1660541", "compartment_display": "endolysosome membrane" }, { "id": "species_10781918", "map_id": "none", "name": "PCSK9:LDLR:Clathrin:AP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10785516", "map_id": "none", "name": "Casein kinase II phosphorylates PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10785514", "map_id": "P53916", "name": "phospho-TEP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10774577", "map_id": "none", "name": "Casein kinase II", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P15790", "map_id": "P15790", "name": "CKA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CKA1", "map_id": "CKA1", "name": "CKA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38930", "map_id": "P38930", "name": "CKB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CKB2", "map_id": "CKB2", "name": "CKB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P19454", "map_id": "P19454", "name": "CKA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CKA2", "map_id": "CKA2", "name": "CKA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787467", "map_id": "none", "name": "TNKS and TNKS2 PARylate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787457", "map_id": "P53916", "name": "phospho-TEP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_197277", "map_id": "CHEBI:17154", "name": "NAM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10787462", "map_id": "P50086", "name": "NAS6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YGR232W", "map_id": "YGR232W", "name": "NAS6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784359", "map_id": "none", "name": "USP13 and OTUD3 deubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10784356", "map_id": "P53916", "name": "TEP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10781697", "map_id": "P38237", "name": "UBP14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10784353", "map_id": "none", "name": "NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10784348", "map_id": "P53916", "name": "TEP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772117", "map_id": "P39940", "name": "RSP5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10785528", "map_id": "none", "name": "Proteasome degrades polyubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10785526", "map_id": "none", "name": "PolyUb-PTEN, K48polyUb-K289-PTEN, PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10784088", "map_id": "none", "name": "RABGGTA binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10784079", "map_id": "Q00618", "name": "BET4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YJL031C", "map_id": "YJL031C", "name": "BET4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784084", "map_id": "P20133", "name": "BET2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YPR176C", "map_id": "YPR176C", "name": "BET2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784086", "map_id": "none", "name": "RGGT", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P20133", "map_id": "P20133", "name": "BET2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q00618", "map_id": "Q00618", "name": "BET4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784074", "map_id": "none", "name": "PIDD1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10784068", "map_id": "P08678", "name": "phospho-CYR1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YJL005W", "map_id": "YJL005W", "name": "phospho-CYR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784072", "map_id": "P08678", "name": "phospho-CYR1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10784097", "map_id": "none", "name": "CHM binds RGGT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10784093", "map_id": "P32864", "name": "MRS6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YOR370C", "map_id": "YOR370C", "name": "MRS6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784095", "map_id": "none", "name": "RGGT:CHM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P32864", "map_id": "P32864", "name": "MRS6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784124", "map_id": "none", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_10784120", "map_id": "none", "name": "PRELID1, PRELID3A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "P35200", "map_id": "P35200", "name": "UPS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR168C", "map_id": "YLR168C", "name": "UPS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05776", "map_id": "Q05776", "name": "UPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR193C", "map_id": "YLR193C", "name": "UPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04006", "map_id": "Q04006", "name": "UPS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR185C", "map_id": "YDR185C", "name": "UPS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784101", "map_id": "O60200", "name": "MDM35", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10784122", "map_id": "none", "name": "TRIAP1:PRELID1, PRELID3A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "O60200", "map_id": "O60200", "name": "MDM35", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MDM35", "map_id": "MDM35", "name": "MDM35", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784070", "map_id": "none", "name": "ATM phosphorylates PIDD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10784065", "map_id": "P08678", "name": "CYR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10768327", "map_id": "P38110", "name": "phospho-TEL1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YBL088C", "map_id": "YBL088C", "name": "TEL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784127", "map_id": "none", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_1500590", "map_id": "CHEBI:16337", "name": "PA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_1524101", "map_id": "CHEBI:16337", "name": "PA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10788980", "map_id": "none", "name": "ABCC1 transports BIL from cytosol to extracellular region (blood)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189386", "map_id": "CHEBI:16990", "name": "BIL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9661418", "map_id": "CHEBI:16990", "name": "BIL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10768249", "map_id": "P39109", "name": "YCF1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10779396", "map_id": "none", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779391", "map_id": "none", "name": "p-T68-CHEK2 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P39009", "map_id": "P39009", "name": "phospho-DUN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766387", "map_id": "none", "name": "Recruitment of the Rad9-Hus1-Rad1 complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10766382", "map_id": "none", "name": "Rad17-RFC complex bound to DNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P32641", "map_id": "P32641", "name": "RAD24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER173W", "map_id": "YER173W", "name": "RAD24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10766378", "map_id": "none", "name": "RAD9:HUS1:RAD1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q02574", "map_id": "Q02574", "name": "MEC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR288C", "map_id": "YLR288C", "name": "MEC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08949", "map_id": "Q08949", "name": "DDC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL194W", "map_id": "YPL194W", "name": "DDC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P48581", "map_id": "P48581", "name": "RAD17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR368W", "map_id": "YOR368W", "name": "RAD17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10766384", "map_id": "none", "name": "Rad9-Hus1-Rad1 bound to DNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10787270", "map_id": "none", "name": "Formation of CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787266", "map_id": "none", "name": "Cyclin D", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10787216", "map_id": "none", "name": "CDK4,CDK6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P36005", "map_id": "P36005", "name": "phospho-KDX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL161C", "map_id": "YKL161C", "name": "phospho-KDX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787268", "map_id": "none", "name": "CDK4,CDK6:CCND", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10760833", "map_id": "none", "name": "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760281", "map_id": "none", "name": "RNA primer:origin duplex:DNA polymerase alpha:primase complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_30187", "map_id": "CHEBI:37568", "name": "dTTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29892", "map_id": "CHEBI:61429", "name": "dGTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10785898", "map_id": "none", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10785889", "map_id": "none", "name": "SKP1:CUL1:RBX1:FBXL7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10785894", "map_id": "P38991", "name": "IPL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YPL209C", "map_id": "YPL209C", "name": "IPL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785896", "map_id": "none", "name": "SCF-FBXL7:AURKA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38991", "map_id": "P38991", "name": "IPL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763956", "map_id": "none", "name": "Phosphorylation of Cdc25C at Ser216 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10763791", "map_id": "P23748", "name": "MIH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10763794", "map_id": "P23748", "name": "phospho-MIH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10774551", "map_id": "none", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10774539", "map_id": "none", "name": "CK2 Phosphorylated Condensin I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38170", "map_id": "P38170", "name": "BRN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL097W", "map_id": "YBL097W", "name": "BRN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38989", "map_id": "P38989", "name": "SMC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFR031C", "map_id": "YFR031C", "name": "SMC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12267", "map_id": "Q12267", "name": "SMC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR086W", "map_id": "YLR086W", "name": "SMC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06156", "map_id": "Q06156", "name": "YCS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR272C", "map_id": "YLR272C", "name": "YCS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06680", "map_id": "Q06680", "name": "YCG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR325W", "map_id": "YDR325W", "name": "YCG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10774549", "map_id": "none", "name": "Condensin I", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_2529006", "map_id": "none", "name": "Unknown Phosphatase", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10784202", "map_id": "none", "name": "MDM2 ubiquitinates phosphorylated MDM4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10768310", "map_id": "none", "name": "p-S166,S188-MDM2:p-S346,S367,S403-MDM4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10784199", "map_id": "none", "name": "PolyUb,p-S166,S188-MDM2:PolyUb,p-S342,S367,S403-MDM4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10774378", "map_id": "none", "name": "Phosphorylation of cohesin by PLK1 at chromosomal arms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1598585", "compartment_display": "chromosome" }, { "id": "species_10774363", "map_id": "none", "name": "Sister Chromosomal Arms:Ac-Cohesin:PDS5:p-CDCA5:WAPAL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1598585", "compartment_display": "chromosome", "complex": "true" }, { "id": "P32908", "map_id": "P32908", "name": "SMC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFL008W", "map_id": "YFL008W", "name": "SMC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04264", "map_id": "Q04264", "name": "PDS5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR076C", "map_id": "YMR076C", "name": "PDS5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12158", "map_id": "Q12158", "name": "phospho-MCD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL003W", "map_id": "YDL003W", "name": "phospho-MCD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47037", "map_id": "P47037", "name": "SMC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL074C", "map_id": "YJL074C", "name": "SMC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40541", "map_id": "P40541", "name": "phospho-IRR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL026C", "map_id": "YIL026C", "name": "phospho-IRR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10774375", "map_id": "none", "name": "Sister Chromosomal Arms:p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1598585", "compartment_display": "chromosome", "complex": "true" }, { "id": "species_10768675", "map_id": "P32562", "name": "CDC5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10788671", "map_id": "none", "name": "LBR binds KPNB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10788667", "map_id": "P32462", "name": "phospho-ERG24", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10768074", "map_id": "Q06142", "name": "KAP95", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YLR347C", "map_id": "YLR347C", "name": "KAP95", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788669", "map_id": "none", "name": "p-S71,S86-LBR:KPNB1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "Q06142", "map_id": "Q06142", "name": "KAP95", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763796", "map_id": "none", "name": "Phosphorylation of Cdc25C at Ser 216 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10774466", "map_id": "none", "name": "Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10774462", "map_id": "none", "name": "Cohesin:PDS5:WAPAL:Centromere", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10774464", "map_id": "none", "name": "Ac-Cohesin:PDS5:WAPAL:Centromere", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10774449", "map_id": "P43605", "name": "ECO1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YFR027W", "map_id": "YFR027W", "name": "ECO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766462", "map_id": "none", "name": "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10766260", "map_id": "P53197", "name": "CDH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10766262", "map_id": "P53197", "name": "phospho-CDH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10787375", "map_id": "none", "name": "CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10787337", "map_id": "none", "name": "CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10787373", "map_id": "none", "name": "p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10788685", "map_id": "none", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788673", "map_id": "none", "name": "RAN:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32835", "map_id": "P32835", "name": "GSP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR293C", "map_id": "YLR293C", "name": "GSP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9624879", "map_id": "none", "name": "Nuclear envelope vesicle", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10788683", "map_id": "none", "name": "RAN:GTP:Nuclear envelope vesicles", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10764018", "map_id": "none", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10763979", "map_id": "none", "name": "Homologues of p-T286-CCND1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764006", "map_id": "none", "name": "Homologues of p-T286-CCND1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10766207", "map_id": "none", "name": "Translocation of Cdc25 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10766203", "map_id": "none", "name": "CDC25", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10766205", "map_id": "none", "name": "CDC25", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10788374", "map_id": "none", "name": "p-S216-CDC25C translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10760284", "map_id": "none", "name": "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10774945", "map_id": "none", "name": "Cytosolic PLK1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10766199", "map_id": "none", "name": "Translocation of active Cdc25C to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10766197", "map_id": "P23748", "name": "phospho-MIH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10789351", "map_id": "none", "name": "CDK6 inhibitors bind CDK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_9754132", "map_id": "none", "name": "CDK6 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "LigandDisplayForward?ligandId=10426", "map_id": "LigandDisplayForward?ligandId=10426", "name": "LigandDisplayForward?ligandId=10426", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=9923", "map_id": "LigandDisplayForward?ligandId=9923", "name": "LigandDisplayForward?ligandId=9923", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=9626", "map_id": "LigandDisplayForward?ligandId=9626", "name": "LigandDisplayForward?ligandId=9626", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=11189", "map_id": "LigandDisplayForward?ligandId=11189", "name": "LigandDisplayForward?ligandId=11189", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7383", "map_id": "LigandDisplayForward?ligandId=7383", "name": "LigandDisplayForward?ligandId=7383", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7382", "map_id": "LigandDisplayForward?ligandId=7382", "name": "LigandDisplayForward?ligandId=7382", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7380", "map_id": "LigandDisplayForward?ligandId=7380", "name": "LigandDisplayForward?ligandId=7380", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=5969", "map_id": "LigandDisplayForward?ligandId=5969", "name": "LigandDisplayForward?ligandId=5969", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7934", "map_id": "LigandDisplayForward?ligandId=7934", "name": "LigandDisplayForward?ligandId=7934", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=10313", "map_id": "LigandDisplayForward?ligandId=10313", "name": "LigandDisplayForward?ligandId=10313", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7379", "map_id": "LigandDisplayForward?ligandId=7379", "name": "LigandDisplayForward?ligandId=7379", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787355", "map_id": "none", "name": "p-T177-CDK6:CCND", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10789349", "map_id": "none", "name": "p-T177-CDK6:CCND:CDK6 inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10788688", "map_id": "none", "name": "RAN stimulates fusion of nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767791", "map_id": "none", "name": "RAN:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_9624890", "map_id": "none", "name": "Fused nuclear envelope vesicles", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10774940", "map_id": "none", "name": "SUMO1:RANGAP1 homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "P11745", "map_id": "P11745", "name": "RNA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR235C", "map_id": "YMR235C", "name": "RNA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12306", "map_id": "Q12306", "name": "SMT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR510W", "map_id": "YDR510W", "name": "SMT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789361", "map_id": "none", "name": "CDK4 inhibitors bind CDK4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10787371", "map_id": "none", "name": "p-T172-CDK4:CCND", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_9754127", "map_id": "none", "name": "CDK4 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "LigandDisplayForward?ligandId=7938", "map_id": "LigandDisplayForward?ligandId=7938", "name": "LigandDisplayForward?ligandId=7938", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=5950", "map_id": "LigandDisplayForward?ligandId=5950", "name": "LigandDisplayForward?ligandId=5950", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=5707", "map_id": "LigandDisplayForward?ligandId=5707", "name": "LigandDisplayForward?ligandId=5707", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7744", "map_id": "LigandDisplayForward?ligandId=7744", "name": "LigandDisplayForward?ligandId=7744", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "pubchem.compound:9933545", "map_id": "pubchem.compound:9933545", "name": "pubchem.compound:9933545", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=8203", "map_id": "LigandDisplayForward?ligandId=8203", "name": "LigandDisplayForward?ligandId=8203", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=5680", "map_id": "LigandDisplayForward?ligandId=5680", "name": "LigandDisplayForward?ligandId=5680", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10789359", "map_id": "none", "name": "p-T172-CDK4:CCND:CDK4 inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10774454", "map_id": "none", "name": "Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10774436", "map_id": "none", "name": "Cohesin:PDS5:WAPAL:Chromosomal Arm", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10774444", "map_id": "none", "name": "Ac-Cohesin:PDS5:WAPAL:Chromosomal Arm", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10774580", "map_id": "none", "name": "CK2 phosphorylates condensin I subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10766243", "map_id": "none", "name": "Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10766239", "map_id": "none", "name": "CCNA:p-Y15-CDK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10766241", "map_id": "none", "name": "CCNA:CDK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10774394", "map_id": "none", "name": "Autocleavage of ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10774383", "map_id": "Q03018", "name": "ESP1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YGR098C", "map_id": "YGR098C", "name": "ESP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10774391", "map_id": "none", "name": "ESPL1 Autocleaved", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q03018", "map_id": "Q03018", "name": "ESP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765338", "map_id": "none", "name": "Formation of the MCC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10765330", "map_id": "P40958", "name": "MAD2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YJL030W", "map_id": "YJL030W", "name": "MAD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765320", "map_id": "P26449", "name": "BUB3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YOR026W", "map_id": "YOR026W", "name": "BUB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765315", "map_id": "none", "name": "Homologues of BUB1B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P47074", "map_id": "P47074", "name": "MAD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL013C", "map_id": "YJL013C", "name": "MAD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41695", "map_id": "P41695", "name": "BUB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR188C", "map_id": "YGR188C", "name": "BUB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765325", "map_id": "P26309", "name": "CDC20", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YGL116W", "map_id": "YGL116W", "name": "CDC20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765332", "map_id": "none", "name": "hBUBR1:hBUB3:MAD2*:CDC20 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P40958", "map_id": "P40958", "name": "MAD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P26309", "map_id": "P26309", "name": "CDC20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P26449", "map_id": "P26449", "name": "BUB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765336", "map_id": "none", "name": "Inactivation of APC/C via CDC20 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10765334", "map_id": "none", "name": "MAD2*CDC20 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10774266", "map_id": "none", "name": "PLK1 phosphorylates GORASP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10774258", "map_id": "none", "name": "p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "P32562", "map_id": "P32562", "name": "CDC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04410", "map_id": "Q04410", "name": "GRH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR517W", "map_id": "YDR517W", "name": "GRH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10774263", "map_id": "none", "name": "p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10784232", "map_id": "none", "name": "ATM phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10768288", "map_id": "none", "name": "Homologues of p-S166,S188-MDM2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10784230", "map_id": "none", "name": "Homologues of p-5S,T-MDM2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10766264", "map_id": "none", "name": "Translocation of Cyclin A:Cdk2 complexes to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10766227", "map_id": "none", "name": "CCNA:CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10768330", "map_id": "none", "name": "Phosphorylation of MDM4 by ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10768320", "map_id": "none", "name": "p-S166,S188-MDM2:MDM4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10768298", "map_id": "none", "name": "p-S166,S188-MDM2:p-S403-MDM4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10777308", "map_id": "none", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_5221122", "map_id": "CHEBI:29089", "name": "1,2-diacyl-glycerol 3-phosphate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_5221124", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10776501", "map_id": "P32567", "name": "PAH1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "reaction_10768312", "map_id": "none", "name": "Phosphorylation of MDM4 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10764016", "map_id": "none", "name": "Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10763990", "map_id": "none", "name": "phospho(T286)-Cyclin D1:Cdk4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764014", "map_id": "none", "name": "phospho(T286)-Cyclin D1:Cdk4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10766229", "map_id": "none", "name": "Formation of Cyclin A:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10766189", "map_id": "none", "name": "CCNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10774943", "map_id": "none", "name": "UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10774930", "map_id": "none", "name": "RANGAP1 homodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "species_10774813", "map_id": "none", "name": "SUMO1:C93-UBE2I", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P50623", "map_id": "P50623", "name": "UBC9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL064W", "map_id": "YDL064W", "name": "UBC9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10774805", "map_id": "P50623", "name": "UBC9", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10787339", "map_id": "none", "name": "Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10787303", "map_id": "none", "name": "CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788681", "map_id": "none", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1598585", "compartment_display": "chromosome" }, { "id": "species_10788678", "map_id": "P21827", "name": "SRM1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1598585", "compartment_display": "chromosome", "complex": "false" }, { "id": "YGL097W", "map_id": "YGL097W", "name": "SRM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766195", "map_id": "none", "name": "Translocation of Cdc25B to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10766191", "map_id": "P23748", "name": "MIH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10766193", "map_id": "P23748", "name": "MIH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10766465", "map_id": "none", "name": "CAK-mediated phosphorylation of Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10779393", "map_id": "none", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779389", "map_id": "P39009", "name": "phospho-DUN1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10784210", "map_id": "none", "name": "MDM2 forms homo- or heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10784204", "map_id": "none", "name": "p-S166,S188-MDM2,MDM4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10784208", "map_id": "none", "name": "p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10785940", "map_id": "none", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10785937", "map_id": "none", "name": "SCF-FBXL7:PolyUb-AURKA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10764022", "map_id": "none", "name": "Proteasome mediated degradation of Cyclin D1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764020", "map_id": "none", "name": "multi-ubiquitinated phospho-(T286) Cyclin D1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10785942", "map_id": "none", "name": "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10772729", "map_id": "none", "name": "Activation of TWIK-related K+ channel (TREK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10772726", "map_id": "none", "name": "TREK homodimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10766923", "map_id": "none", "name": "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_195691", "map_id": "CHEBI:16290", "name": "CHdOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_195655", "map_id": "CHEBI:27910", "name": "7dhDESOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10766920", "map_id": "P32353", "name": "ERG3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YLR056W", "map_id": "YLR056W", "name": "ERG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764912", "map_id": "none", "name": "Hydrolysis of phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_140356", "map_id": "CHEBI:15843", "name": "ARA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_428981", "map_id": "CHEBI:17504", "name": "LPC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10764907", "map_id": "none", "name": "Active PLA2:phosphatidylcholine", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_429802", "map_id": "CHEBI:16110", "name": "PC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10764967", "map_id": "none", "name": "Inactivation of PLC beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764872", "map_id": "none", "name": "Activated PLC beta 1/4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10764856", "map_id": "P32383", "name": "PLC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10764909", "map_id": "none", "name": "Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10764875", "map_id": "none", "name": "PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10764925", "map_id": "none", "name": "Phosphorylation of cPLA2 by ERK-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764922", "map_id": "none", "name": "Homologues of PLA2G4A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10779083", "map_id": "none", "name": "ABCC2 transports BMG,BDG from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5679042", "map_id": "none", "name": "BMG,BDG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_5679034", "map_id": "none", "name": "BMG,BDG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10774756", "map_id": "none", "name": "Conjugation of SUMO1 to UBA2:SAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10774743", "map_id": "Q12306", "name": "SMT3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10774738", "map_id": "none", "name": "UBA2:SAE1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P52488", "map_id": "P52488", "name": "UBA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR390C", "map_id": "YDR390C", "name": "UBA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06624", "map_id": "Q06624", "name": "AOS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR180W", "map_id": "YPR180W", "name": "AOS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10774753", "map_id": "none", "name": "SUMO1:UBA2:SAE1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10774681", "map_id": "none", "name": "Autophosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10774679", "map_id": "none", "name": "p-5Y-PKC-theta:DAG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10766028", "map_id": "none", "name": "Phosphorylation of human JNKs by activated MKK4/MKK7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10765968", "map_id": "P41808", "name": "SMK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766025", "map_id": "none", "name": "p-MAP2K4/p-MAP2K7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32490", "map_id": "P32490", "name": "phospho-MKK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR231W", "map_id": "YOR231W", "name": "phospho-MKK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32491", "map_id": "P32491", "name": "phospho-MKK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL140C", "map_id": "YPL140C", "name": "phospho-MKK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P08018", "map_id": "P08018", "name": "phospho-PBS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL128C", "map_id": "YJL128C", "name": "phospho-PBS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770904", "map_id": "none", "name": "Pellino ubiquitinates IRAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770887", "map_id": "none", "name": "hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P43633", "map_id": "P43633", "name": "phospho-ALK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL021W", "map_id": "YGL021W", "name": "phospho-ALK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32789", "map_id": "P32789", "name": "phospho-ALK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL009W", "map_id": "YBL009W", "name": "phospho-ALK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53152", "map_id": "P53152", "name": "MMS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MMS2", "map_id": "MMS2", "name": "MMS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P52490", "map_id": "P52490", "name": "UBC13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "UBC13", "map_id": "UBC13", "name": "UBC13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10770901", "map_id": "none", "name": "K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10789090", "map_id": "none", "name": "FKBP1A binds tacrolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9678991", "map_id": "LigandDisplayForward?ligandId=6784", "name": "tacrolimus", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10789088", "map_id": "none", "name": "FKBP1A:tacrolimus", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10769144", "map_id": "none", "name": "p-S400-Cot phosphorylates NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769141", "map_id": "P25390", "name": "phospho-SSK22", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10768963", "map_id": "none", "name": "Homologues of p-S400-MAP3K8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P25390", "map_id": "P25390", "name": "phospho-SSK22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53599", "map_id": "P53599", "name": "phospho-SSK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNR031C", "map_id": "YNR031C", "name": "phospho-SSK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767769", "map_id": "none", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10767354", "map_id": "none", "name": "p-MAPK3/MAPK1/MAPK7 dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P41808", "map_id": "P41808", "name": "phospho-SMK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10767374", "map_id": "none", "name": "MAPK3/MAPK1/MAPK7 dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10767766", "map_id": "none", "name": "ERK-specific DUSP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P40479", "map_id": "P40479", "name": "SDP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL113W", "map_id": "YIL113W", "name": "SDP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38590", "map_id": "P38590", "name": "MSG5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL053W", "map_id": "YNL053W", "name": "MSG5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772408", "map_id": "none", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10772358", "map_id": "none", "name": "Ubiquitin:E2 conjugating enzymes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P22515", "map_id": "P22515", "name": "UBA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL210W", "map_id": "YKL210W", "name": "UBA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P15732", "map_id": "P15732", "name": "UBC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR059C", "map_id": "YDR059C", "name": "UBC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P28263", "map_id": "P28263", "name": "UBC8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL012W", "map_id": "YEL012W", "name": "UBC8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02159", "map_id": "Q02159", "name": "UBC7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR022W", "map_id": "YMR022W", "name": "UBC7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P33296", "map_id": "P33296", "name": "UBC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER100W", "map_id": "YER100W", "name": "UBC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P52492", "map_id": "P52492", "name": "UBC11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR339C", "map_id": "YOR339C", "name": "UBC11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P15731", "map_id": "P15731", "name": "UBC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR082C", "map_id": "YBR082C", "name": "UBC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P06104", "map_id": "P06104", "name": "RAD6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL058W", "map_id": "YGL058W", "name": "RAD6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P14682", "map_id": "P14682", "name": "CDC34", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR054C", "map_id": "YDR054C", "name": "CDC34", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P52491", "map_id": "P52491", "name": "UBC12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { 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"sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P31412", "map_id": "P31412", "name": "VMA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL080W", "map_id": "YKL080W", "name": "VMA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32610", "map_id": "P32610", "name": "VMA8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL051W", "map_id": "YEL051W", "name": "VMA8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769326", "map_id": "none", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769321", "map_id": "P16603", "name": "NCP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10767230", "map_id": "none", "name": "p38MAPK phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765922", "map_id": "P32485", "name": "phospho-HOG1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10787198", "map_id": "none", "name": "THOP1 cleaves oligopeptide fragment (8-16aa)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_983032", "map_id": "CHEBI:25676", "name": "oligopeptide fragment (8-16aa)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8955634", "map_id": "CHEBI:25676", "name": "oligopeptide fragment (3-7aa)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10787195", "map_id": "P25375", "name": "PRD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YCL057W", "map_id": "YCL057W", "name": "PRD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772582", "map_id": "none", "name": "PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10765242", "map_id": "P24583", "name": "PKC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10765252", "map_id": "none", "name": "Activated PKC beta", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10775012", "map_id": "none", "name": "MRE11 binds cytosolic DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_874088", "map_id": "CHEBI:16991", "name": "Double-stranded DNA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10775008", "map_id": "P32829", "name": "MRE11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10775010", "map_id": "none", "name": "MRE11:dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32829", "map_id": "P32829", "name": "MRE11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MRE11", "map_id": "MRE11", "name": "MRE11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10783010", "map_id": "none", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6800173", "compartment_display": "tertiary granule lumen" }, { "id": "species_10782978", "map_id": "none", "name": "Tertiary granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6800173", "compartment_display": "tertiary granule lumen", "complex": "true" }, { "id": "P49954", "map_id": "P49954", "name": "NIT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR351C", "map_id": "YLR351C", "name": "NIT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36110", "map_id": "P36110", "name": "PRY2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR013W", "map_id": "YKR013W", "name": "PRY2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47033", "map_id": "P47033", "name": "PRY3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL078C", "map_id": "YJL078C", "name": "PRY3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41912", "map_id": "P41912", "name": "SHR5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL110W", "map_id": "YOL110W", "name": "SHR5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10740", "map_id": "Q10740", "name": "LAP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL045W", "map_id": "YNL045W", "name": "LAP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P43599", "map_id": "P43599", "name": "QPCT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFR018C", "map_id": "YFR018C", "name": "QPCT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P07267", "map_id": "P07267", "name": "PEP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL154C", "map_id": "YPL154C", "name": "PEP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40547", "map_id": "P40547", "name": "VID28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL017C", "map_id": "YIL017C", "name": "VID28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P33401", "map_id": "P33401", "name": "PGM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL127W", "map_id": "YKL127W", "name": "PGM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47032", "map_id": "P47032", "name": "PRY1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL079C", "map_id": "YJL079C", "name": "PRY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10783008", "map_id": "none", "name": "Tertiary granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10770716", "map_id": "none", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10770713", "map_id": "none", "name": "p38 MAPK:MAPKAPK2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P36003", "map_id": "P36003", "name": "phospho-NNK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10770632", "map_id": "none", "name": "p-p38 MAPK: MAPKAPK2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10770705", "map_id": "none", "name": "p-S189,T193-MAP2K3, p-S207,T211-MAP2K6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10774045", "map_id": "none", "name": "Conversion of PA into DAG by PAP-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10774042", "map_id": "none", "name": "Phosphatidate phosphatase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q05521", "map_id": "Q05521", "name": "DPP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR284C", "map_id": "YDR284C", "name": "DPP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04396", "map_id": "Q04396", "name": "LPP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR503C", "map_id": "YDR503C", "name": "LPP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10783692", "map_id": "none", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1470028", "compartment_display": "azurophil granule lumen" }, { "id": "species_10783636", "map_id": "none", "name": "Azurophil granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1470028", "compartment_display": "azurophil granule lumen", "complex": "true" }, { "id": "P17555", "map_id": "P17555", "name": "SRV2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL138W", "map_id": "YNL138W", "name": "SRV2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40358", "map_id": "P40358", "name": "JEM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": 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"Q03630", "name": "BET5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML077W", "map_id": "YML077W", "name": "BET5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53094", "map_id": "P53094", "name": "MDS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL197W", "map_id": "YGL197W", "name": "MDS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03862", "map_id": "Q03862", "name": "ARX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR101C", "map_id": "YDR101C", "name": "ARX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00812", "map_id": "P00812", "name": "CAR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL111W", "map_id": "YPL111W", "name": "CAR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08412", "map_id": "Q08412", "name": "CUE5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR042W", "map_id": "YOR042W", "name": "CUE5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32634", "map_id": "P32634", "name": "PMD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER132C", "map_id": "YER132C", "name": "PMD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40557", "map_id": "P40557", "name": "EPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL005W", "map_id": "YIL005W", "name": "EPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02933", "map_id": "Q02933", "name": "RNY1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL123C", "map_id": "YPL123C", "name": "RNY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P34227", "map_id": "P34227", "name": "PRX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL064C", "map_id": "YBL064C", "name": "PRX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40568", "map_id": "P40568", "name": "DSN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIR010W", "map_id": "YIR010W", "name": "DSN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10783690", "map_id": "none", "name": "Azurophil granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10783061", "map_id": "none", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6799713", "compartment_display": "tertiary granule membrane" }, { "id": "species_10783055", "map_id": "none", "name": "Tertiary granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6799713", "compartment_display": "tertiary granule membrane", "complex": "true" }, { "id": "P32660", "map_id": "P32660", "name": "DNF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER166W", "map_id": "YER166W", "name": "DNF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39524", "map_id": "P39524", "name": "DRS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL026C", "map_id": "YAL026C", "name": "DRS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12675", "map_id": "Q12675", "name": "DNF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR093W", "map_id": "YDR093W", "name": "DNF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P31109", "map_id": "P31109", "name": "SNC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL030W", "map_id": "YAL030W", "name": "SNC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12674", "map_id": "Q12674", "name": "DNF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR162C", "map_id": "YMR162C", "name": "DNF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10783059", "map_id": "none", "name": "Tertiary granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10766032", "map_id": "none", "name": "Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765963", "map_id": "P03069", "name": "phospho-GCN4", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YEL009C", "map_id": "YEL009C", "name": "phospho-GCN4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10766030", "map_id": "none", "name": "p-2S-cJUN:p-2T-ATF2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P03069", "map_id": "P03069", "name": "phospho-GCN4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772715", "map_id": "none", "name": "Activation of p38 MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10772704", "map_id": "none", "name": "p38 MAPK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10772712", "map_id": "none", "name": "Phospho-p38 MAPK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10770681", "map_id": "none", "name": "Homologues of p-S207,T211-MAP2K6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10783523", "map_id": "none", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6799371", "compartment_display": "specific granule lumen" }, { "id": "species_10783509", "map_id": "none", "name": "Specific granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6799371", "compartment_display": "specific granule lumen", "complex": "true" }, { "id": "P27796", "map_id": "P27796", "name": "POT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL160C", "map_id": "YIL160C", "name": "POT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10783521", "map_id": "none", "name": "Specific granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10770641", "map_id": "none", "name": "Active p38 MAPK phosphorylates MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10770638", "map_id": "none", "name": "p-p38 MAPK:p-MAPKAPK2/3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10783779", "map_id": "none", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6799351", "compartment_display": "specific granule membrane" }, { "id": "species_10783765", "map_id": "none", "name": "Specific granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6799351", "compartment_display": "specific granule membrane", "complex": "true" }, { "id": "Q06144", "map_id": "Q06144", "name": "ORM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR350W", "map_id": "YLR350W", "name": "ORM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53142", "map_id": "P53142", "name": "VPS73", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL104C", "map_id": "YGL104C", "name": "VPS73", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32901", "map_id": "P32901", "name": "PTR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR093W", "map_id": "YKR093W", "name": "PTR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q00776", "map_id": "Q00776", "name": "APM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL259C", "map_id": "YPL259C", "name": "APM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53224", "map_id": "P53224", "name": "ORM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR038W", "map_id": "YGR038W", "name": "ORM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P33333", "map_id": "P33333", "name": "SLC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL052C", "map_id": "YDL052C", "name": "SLC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25656", "map_id": "P25656", "name": "CDC50", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCR094W", "map_id": "YCR094W", "name": "CDC50", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10783777", "map_id": "none", "name": "Specific granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10771236", "map_id": "none", "name": "SGT1 binds HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10771232", "map_id": "none", "name": "Homologues of HSP90AB1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10771226", "map_id": "Q08446", "name": "SGT1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YOR057W", "map_id": "YOR057W", "name": "SGT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10771234", "map_id": "none", "name": "SUGT1:HSP90", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08446", "map_id": "Q08446", "name": "SGT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772405", "map_id": "none", "name": "E1 mediated ubiquitin activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10772397", "map_id": "none", "name": "Ubiquitin activating E1 enzymes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q99344", "map_id": "Q99344", "name": "UBA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR066W", "map_id": "YPR066W", "name": "UBA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29926", "map_id": "CHEBI:18420", "name": "Mg2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772399", "map_id": "none", "name": "E1 bound ubiquitin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10770762", "map_id": "none", "name": "Activated human JNKs migrate to nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10782924", "map_id": "none", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10782878", "map_id": "none", "name": "Secretory granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "true" }, { "id": "Q99260", "map_id": "Q99260", "name": "YPT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR262C", "map_id": "YLR262C", "name": "YPT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36017", "map_id": "P36017", "name": "VPS21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR089C", "map_id": "YOR089C", "name": "VPS21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P07560", "map_id": "P07560", "name": "SEC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFL005W", "map_id": "YFL005W", "name": "SEC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P48559", "map_id": "P48559", "name": "YPT11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL304W", "map_id": "YNL304W", "name": "YPT11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10782922", "map_id": "none", "name": "Secretory granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10772402", "map_id": "none", "name": "Transfer of ubiquitin from E1 to E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10774030", "map_id": "none", "name": "Autophosphorylation of PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10774027", "map_id": "Q03497", "name": "phospho-STE20", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10774276", "map_id": "none", "name": "PIP3 recruits AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769080", "map_id": "none", "name": "AKT", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10772383", "map_id": "none", "name": "Proteasomal cleavage of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_983123", "map_id": "none", "name": "K48polyUb-antigenic substrate", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_983036", "map_id": "CHEBI:25676", "name": "precursor peptide fragment (>16 aa)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8942986", "map_id": "CHEBI:59869", "name": "L-amino acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10784185", "map_id": "none", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10784177", "map_id": "P11633", "name": "NHP6B", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_166005", "map_id": "CHEBI:16412", "name": "LPS", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10784183", "map_id": "none", "name": "HC23,45-HMGB1:LPS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10774162", "map_id": "none", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2213225", "map_id": "none", "name": "unfolded antigen", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_2213226", "map_id": "none", "name": "MHC class II epitopes", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10774157", "map_id": "P07267", "name": "PEP4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10784181", "map_id": "none", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_181015", "map_id": "CHEBI:28640", "name": "Lipoteichoic acid", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10784179", "map_id": "none", "name": "HC23,45-HMGB1:LTA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10770513", "map_id": "none", "name": "TRAF6 is K63 poly-ubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770504", "map_id": "none", "name": "hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10770510", "map_id": "none", "name": "hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10787872", "map_id": "none", "name": "MAPK8 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10772410", "map_id": "none", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_983035", "map_id": "none", "name": "antigenic substrate", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10772644", "map_id": "none", "name": "Proteasomal clevage of exogenous antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1236719", "map_id": "CHEBI:16670", "name": "Exogenous soluble antigen", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10765954", "map_id": "none", "name": "Phosphorylated MAPKs phosphorylate ATF-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765901", "map_id": "none", "name": "Homologues of ATF2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10765951", "map_id": "none", "name": "Activated MAPK kinases ERK1/2, JNK, p38", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10784297", "map_id": "none", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10768264", "map_id": "P11633", "name": "NHP6B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10769000", "map_id": "none", "name": "Activation of PAKs by RAC1 and CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768994", "map_id": "none", "name": "PAK1,2,3 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10768996", "map_id": "none", "name": "PAK1,2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10768998", "map_id": "none", "name": "PAK1,2,3:CDC42:GTP, RAC1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10770707", "map_id": "none", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770683", "map_id": "none", "name": "p-S189,T193-MAP2K3, p-S207,T211-MAP2K6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10772381", "map_id": "none", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10767125", "map_id": "none", "name": "DAG stimulates protein kinase C-delta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10767117", "map_id": "P24583", "name": "phospho-PKC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10782803", "map_id": "none", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6798757", "compartment_display": "azurophil granule membrane" }, { "id": "species_10782785", "map_id": "none", "name": "Azurophil granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6798757", "compartment_display": "azurophil granule membrane", "complex": "true" }, { "id": "P33767", "map_id": "P33767", "name": "WBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL002C", "map_id": "YEL002C", "name": "WBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03723", "map_id": "Q03723", "name": "OST6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML019W", "map_id": "YML019W", "name": "OST6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P48439", "map_id": "P48439", "name": "OST3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR085W", "map_id": "YOR085W", "name": "OST3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10782801", "map_id": "none", "name": "Azurophil granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10784060", "map_id": "none", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10784052", "map_id": "none", "name": "Ficolin-rich granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6800405", "compartment_display": "ficolin-1-rich granule lumen", "complex": "true" }, { "id": "species_10784058", "map_id": "none", "name": "Ficolin-rich granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10765966", "map_id": "none", "name": "Activated JNKs phosphorylate c-JUN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765959", "map_id": "P03069", "name": "GCN4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10772458", "map_id": "none", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10772455", "map_id": "none", "name": "IFN gamma stimulated aminopeptidases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q01532", "map_id": "Q01532", "name": "LAP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL239W", "map_id": "YNL239W", "name": "LAP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768965", "map_id": "none", "name": "AKT interacts and phosphorylates Cot", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768955", "map_id": "none", "name": "Homologues of MAP3K8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10770645", "map_id": "none", "name": "Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770643", "map_id": "none", "name": "p-p38 MAPK: p-S272,T222,T334-MAPKAPK2, p-S,2T-MAPKAPK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10766862", "map_id": "none", "name": "(24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_193732", "map_id": "CHEBI:27403", "name": "3,7,24THCA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_192307", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_193465", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_193403", "map_id": "CHEBI:28533", "name": "3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_192305", "map_id": "CHEBI:57945", "name": "NADH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10766831", "map_id": "none", "name": "HSD17B4 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "Q02207", "map_id": "Q02207", "name": "FOX2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR009C", "map_id": "YKR009C", "name": "FOX2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786503", "map_id": "none", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8868399", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8868400", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10786500", "map_id": "none", "name": "OSBPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38713", "map_id": "P38713", "name": "OSH3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR073W", "map_id": "YHR073W", "name": "OSH3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12451", "map_id": "Q12451", "name": "OSH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL019C", "map_id": "YDL019C", "name": "OSH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P35845", "map_id": "P35845", "name": "SWH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAR042W", "map_id": "YAR042W", "name": "SWH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P35844", "map_id": "P35844", "name": "KES1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL145C", "map_id": "YPL145C", "name": "KES1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766816", "map_id": "none", "name": "Cholesterol is hydroxylated to 25-hydroxycholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176478", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_192148", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766813", "map_id": "none", "name": "CH25H (Fe2+ cofactor)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P53045", "map_id": "P53045", "name": "ERG25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR060W", "map_id": "YGR060W", "name": "ERG25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766860", "map_id": "none", "name": "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_193422", "map_id": "CHEBI:52050", "name": "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_192339", "map_id": "CHEBI:27379", "name": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10766864", "map_id": "none", "name": "25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_141343", "map_id": "CHEBI:15377", "name": "H2O", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_193459", "map_id": "CHEBI:27393", "name": "25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10766824", "map_id": "none", "name": "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192114", "map_id": "CHEBI:17500", "name": "7 alpha-hydroxycholesterol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_192136", "map_id": "CHEBI:17899", "name": "4CHOL7aOLONE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10766821", "map_id": "P53199", "name": "ERG26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YGL001C", "map_id": "YGL001C", "name": "ERG26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766868", "map_id": "none", "name": "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192189", "map_id": "CHEBI:37640", "name": "CHOL7a,24(S)DIOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_193724", "map_id": "CHEBI:63838", "name": "4CHOL7a,24(S)DONE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10786538", "map_id": "none", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1806217", "map_id": "CHEBI:17526", "name": "PI4P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_1806234", "map_id": "CHEBI:17526", "name": "PI4P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8868393", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10786535", "map_id": "none", "name": "Homologues of OSBP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10766870", "map_id": "none", "name": "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192194", "map_id": "CHEBI:18431", "name": "Cholest-5-ene-3beta,7alpha,27-triol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_193835", "map_id": "CHEBI:48825", "name": "4CHOL7a,27DONE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10766834", "map_id": "none", "name": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_192342", "map_id": "CHEBI:27505", "name": "THCA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10766857", "map_id": "none", "name": "Hydrolysis of choloyl-CoA to cholate and CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_192356", "map_id": "CHEBI:15519", "name": "choloyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_193514", "map_id": "CHEBI:57287", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_193451", "map_id": "CHEBI:16359", "name": "cholate", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10766854", "map_id": "P41903", "name": "TES1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "YJR019C", "map_id": "YJR019C", "name": "TES1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785978", "map_id": "none", "name": "TBC1D25 (OATL1) binds ATG8 homologues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane" }, { "id": "species_10779200", "map_id": "P38182", "name": "ATG8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane", "complex": "false" }, { "id": "YBL078C", "map_id": "YBL078C", "name": "ATG8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785974", "map_id": "P48365", "name": "GYP7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5683636", "compartment_display": "autophagosome", "complex": "false" }, { "id": "YDL234C", "map_id": "YDL234C", "name": "GYP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785976", "map_id": "none", "name": "TBC1D25:ATG8 homoogues", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane", "complex": "true" }, { "id": "P48365", "map_id": "P48365", "name": "GYP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38182", "map_id": "P38182", "name": "ATG8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786878", "map_id": "none", "name": "RIC1-RGP1 exchanges GTP for GDP on RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10786865", "map_id": "none", "name": "GGC-RAB6:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786790", "map_id": "none", "name": "GDIs,CHMs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786869", "map_id": "none", "name": "GGC-RAB6:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "species_10786875", "map_id": "none", "name": "RIC1:RGP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P16664", "map_id": "P16664", "name": "RGP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR137W", "map_id": "YDR137W", "name": "RGP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40395", "map_id": "P40395", "name": "RIC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR039C", "map_id": "YLR039C", "name": "RIC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785971", "map_id": "none", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10785946", "map_id": "none", "name": "RAB7A:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10785964", "map_id": "none", "name": "RAB7:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10785969", "map_id": "P48365", "name": "GYP7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10785951", "map_id": "none", "name": "TBC1D2A accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10785948", "map_id": "none", "name": "RAB7A:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10786851", "map_id": "none", "name": "RAB8 GEFs exchange GTP for GDP on RAB8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10786842", "map_id": "none", "name": "GGC-RAB8:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786848", "map_id": "none", "name": "GGC-RAB8:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "species_10778221", "map_id": "P17065", "name": "SEC2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YNL272C", "map_id": "YNL272C", "name": "SEC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785960", "map_id": "none", "name": "TBC1D11 binds RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10785468", "map_id": "none", "name": "RAB6:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10785956", "map_id": "Q12344", "name": "GYP5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YPL249C", "map_id": "YPL249C", "name": "GYP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785958", "map_id": "none", "name": "RABGAP1:RAB6:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q12344", "map_id": "Q12344", "name": "GYP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786959", "map_id": "none", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane" }, { "id": "species_10786946", "map_id": "none", "name": "GGC-RAB1:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786956", "map_id": "none", "name": "GGC-RAB1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane", "complex": "true" }, { "id": "species_10781391", "map_id": "none", "name": "TRAPPCII", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38334", "map_id": "P38334", "name": "TRS20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR254C", "map_id": "YBR254C", "name": "TRS20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03784", "map_id": "Q03784", "name": "TRS23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR246W", "map_id": "YDR246W", "name": "TRS23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36149", "map_id": "P36149", "name": "BET3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR068C", "map_id": "YKR068C", "name": "BET3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04183", "map_id": "Q04183", "name": "TRS120", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR407C", "map_id": "YDR407C", "name": "TRS120", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03337", "map_id": "Q03337", "name": "TRS31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR472W", "map_id": "YDR472W", "name": "TRS31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03660", "map_id": "Q03660", "name": "TRS130", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR218C", "map_id": "YMR218C", "name": "TRS130", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q99394", "map_id": "Q99394", "name": "TRS33", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR115C", "map_id": "YOR115C", "name": "TRS33", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786801", "map_id": "none", "name": "RAB3 GEFs exchange GTP for GDP on RAB3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane" }, { "id": "species_10786792", "map_id": "none", "name": "GGC-RAB3A:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786796", "map_id": "none", "name": "GGC-RAB3A:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "true" }, { "id": "species_10786798", "map_id": "P17065", "name": "SEC2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10786938", "map_id": "none", "name": "MON1:CCZ1 exchanges GTP for GDP on RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10786915", "map_id": "none", "name": "GGC-RAB7:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786921", "map_id": "none", "name": "GGC-RAB7:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10786935", "map_id": "none", "name": "MON1:CCZ1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38273", "map_id": "P38273", "name": "CCZ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR131W", "map_id": "YBR131W", "name": "CCZ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53129", "map_id": "P53129", "name": "MON1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL124C", "map_id": "YGL124C", "name": "MON1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771192", "map_id": "none", "name": "SLC29A3 transports nucleosides from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_727782", "map_id": "none", "name": "nucleosides", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "CHEBI:17748", "map_id": "CHEBI:17748", "name": "CHEBI:17748", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17596", "map_id": "CHEBI:17596", "name": "CHEBI:17596", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17562", "map_id": "CHEBI:17562", "name": "CHEBI:17562", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16704", "map_id": "CHEBI:16704", "name": "CHEBI:16704", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16750", "map_id": "CHEBI:16750", "name": "CHEBI:16750", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_727746", "map_id": "none", "name": "nucleosides", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10771189", "map_id": "P31381", "name": "FUN26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "reaction_10764488", "map_id": "none", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_179743", "map_id": "none", "name": "ligands of SLC28A3 & 29A1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_179737", "map_id": "none", "name": "ligands of SLC28A3 & 29A1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10765594", "map_id": "none", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10765591", "map_id": "none", "name": "SLC25A5,6 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P18239", "map_id": "P18239", "name": "PET9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL030C", "map_id": "YBL030C", "name": "PET9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P18238", "map_id": "P18238", "name": "AAC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR085W", "map_id": "YBR085W", "name": "AAC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P04710", "map_id": "P04710", "name": "AAC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "AAC1", "map_id": "AAC1", "name": "AAC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764483", "map_id": "none", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_179747", "map_id": "none", "name": "ligands of SLC29A2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_113599", "map_id": "CHEBI:17368", "name": "Hyp", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:17821", "map_id": "CHEBI:17821", "name": "CHEBI:17821", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29554", "map_id": "CHEBI:17568", "name": "Ura", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "CHEBI:16040", "map_id": "CHEBI:16040", "name": "CHEBI:16040", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_83956", "map_id": "CHEBI:16235", "name": "Gua", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_179742", "map_id": "none", "name": "ligands of SLC29A2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10764478", "map_id": "P31381", "name": "FUN26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10764485", "map_id": "none", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10764490", "map_id": "none", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10774173", "map_id": "none", "name": "DeMQ10H2 is methylated to Q10H2 by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2162212", "map_id": "CHEBI:64182", "name": "DeMQ10H2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162265", "map_id": "CHEBI:15414", "name": "AdoMet", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162252", "map_id": "CHEBI:16680", "name": "AdoHcy", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162198", "map_id": "CHEBI:64183", "name": "Q10H2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10774170", "map_id": "P27680", "name": "COQ3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "YOL096C", "map_id": "YOL096C", "name": "COQ3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10774183", "map_id": "none", "name": "DHDB is methylated to MHDB by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2162209", "map_id": "CHEBI:50775", "name": "DHDB", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162215", "map_id": "CHEBI:50776", "name": "MHDB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10774197", "map_id": "none", "name": "FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2162256", "map_id": "CHEBI:16584", "name": "IPPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162257", "map_id": "CHEBI:17407", "name": "FPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162214", "map_id": "CHEBI:61011", "name": "all-E-10PrP2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_159450", "map_id": "CHEBI:33019", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10774194", "map_id": "none", "name": "PDSS1/2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P18900", "map_id": "P18900", "name": "COQ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR003W", "map_id": "YBR003W", "name": "COQ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768904", "map_id": "none", "name": "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_389545", "map_id": "CHEBI:151", "name": "ISCIT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10768901", "map_id": "none", "name": "IDH1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773350", "map_id": "none", "name": "BH2 binding can lead to eNOS uncoupling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1497857", "map_id": "CHEBI:15375", "name": "BH2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10773348", "map_id": "none", "name": "p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10772915", "map_id": "none", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1474124", "map_id": "CHEBI:18372", "name": "DHNTP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772912", "map_id": "none", "name": "GCH1 decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P51601", "map_id": "P51601", "name": "FOL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR267C", "map_id": "YGR267C", "name": "FOL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29502", "map_id": "CHEBI:58095", "name": "L-Phe", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10774180", "map_id": "none", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_2162213", "map_id": "CHEBI:30763", "name": "PHB", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162207", "map_id": "CHEBI:64136", "name": "DHB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10774177", "map_id": "P32378", "name": "COQ2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10781221", "map_id": "none", "name": "TP53BP1 associates with H4K20Me2 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779351", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P46995", "map_id": "P46995", "name": "SET2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL168C", "map_id": "YJL168C", "name": "SET2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53924", "map_id": "P53924", "name": "DMA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL116W", "map_id": "YNL116W", "name": "DMA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04195", "map_id": "Q04195", "name": "SIZ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR409W", "map_id": "YDR409W", "name": "SIZ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P12753", "map_id": "P12753", "name": "DNA repair protein RAD50", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "DNA repair protein RAD50", "map_id": "DNA repair protein RAD50", "name": "DNA repair protein RAD50", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12216", "map_id": "Q12216", "name": "NFI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR156C", "map_id": "YOR156C", "name": "NFI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P34218", "map_id": "P34218", "name": "SAS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL052C", "map_id": "YBL052C", "name": "SAS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38110", "map_id": "P38110", "name": "TEL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10774864", "map_id": "P14737", "name": "RAD9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YDR217C", "map_id": "YDR217C", "name": "RAD9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10779374", "map_id": "none", "name": "DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:TP53BP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P14737", "map_id": "P14737", "name": "RAD9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10777638", "map_id": "none", "name": "MSH2:MSH3 binds insertion/deletion loop of 2 bases or more", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5358527", "map_id": "none", "name": "DNA containing IDL of 2 or more bases", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10777634", "map_id": "none", "name": "MSH2:MSH3:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P25336", "map_id": "P25336", "name": "MSH3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCR092C", "map_id": "YCR092C", "name": "MSH3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25847", "map_id": "P25847", "name": "MSH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL090W", "map_id": "YOL090W", "name": "MSH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10777636", "map_id": "none", "name": "MSH2:MSH3:ADP:DNA containing IDL of 2 bases or more", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781856", "map_id": "none", "name": "DNA polymerases delta, epsilon or kappa bind the TC-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781852", "map_id": "none", "name": "PCNA homotrimer,MonoUb:K164-PCNA homotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10781840", "map_id": "none", "name": "TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P21374", "map_id": "P21374", "name": "ISY1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR050W", "map_id": "YJR050W", "name": "ISY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32523", "map_id": "P32523", "name": "PRP19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLL036C", "map_id": "YLL036C", "name": "PRP19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40352", "map_id": "P40352", "name": "RAD26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR035W", "map_id": "YJR035W", "name": "RAD26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P06777", "map_id": "P06777", "name": "RAD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL022W", "map_id": "YPL022W", "name": "RAD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04048", "map_id": "Q04048", "name": "SYF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR416W", "map_id": "YDR416W", "name": "SYF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P07276", "map_id": "P07276", "name": "RAD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR258C", "map_id": "YGR258C", "name": "RAD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12021", "map_id": "Q12021", "name": "RAD28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR030C", "map_id": "YDR030C", "name": "RAD28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10781854", "map_id": "none", "name": "TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778491", "map_id": "none", "name": "USP1:WDR48 deubiquitinates monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778486", "map_id": "none", "name": "MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q99247", "map_id": "Q99247", "name": "DUF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL087C", "map_id": "YOL087C", "name": "DUF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36026", "map_id": "P36026", "name": "UBP11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR098C", "map_id": "YKR098C", "name": "UBP11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25037", "map_id": "P25037", "name": "UBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL122W", "map_id": "YDL122W", "name": "UBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39967", "map_id": "P39967", "name": "UBP9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER098W", "map_id": "YER098W", "name": "UBP9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40453", "map_id": "P40453", "name": "UBP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL156W", "map_id": "YIL156W", "name": "UBP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10778488", "map_id": "none", "name": "PCNA:RPA:RFC:Damaged DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10778482", "map_id": "none", "name": "USP1:WDR48", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10777795", "map_id": "none", "name": "Formation of MSH2:MSH3 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10777614", "map_id": "P25847", "name": "MSH2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10777632", "map_id": "P25336", "name": "MSH3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10779178", "map_id": "none", "name": "KAT5 acetylates ATM at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779173", "map_id": "none", "name": "DNA DSBs:MRN:ATM dimer:KAT5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779175", "map_id": "none", "name": "DNA DSBs:MRN:Ac-K3016-ATM dimer:KAT5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781860", "map_id": "none", "name": "Ligation of newly synthesized repair patch to incised DNA in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781847", "map_id": "none", "name": "TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10781049", "map_id": "none", "name": "(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10781858", "map_id": "none", "name": "TC-NER post-incision complex:dsDNA with transcription bubble", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781753", "map_id": "none", "name": "ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781734", "map_id": "none", "name": "Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10781750", "map_id": "none", "name": "Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764704", "map_id": "none", "name": "Cleavage of cytosine glycol by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764701", "map_id": "none", "name": "NTHL1:Cg-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q08214", "map_id": "Q08214", "name": "NTG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL043C", "map_id": "YOL043C", "name": "NTG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_110225", "map_id": "CHEBI:29127", "name": "Cg", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10764694", "map_id": "none", "name": "NTHL1:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764171", "map_id": "none", "name": "Formation of RAD52 heptameric ring structure complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764167", "map_id": "P06778", "name": "RAD52", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YML032C", "map_id": "YML032C", "name": "RAD52", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764169", "map_id": "none", "name": "RAD52 heptamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P06778", "map_id": "P06778", "name": "RAD52", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764737", "map_id": "none", "name": "Excision of FapyG by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764734", "map_id": "none", "name": "OGG1:FapyG-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P53397", "map_id": "P53397", "name": "OGG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML060W", "map_id": "YML060W", "name": "OGG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764729", "map_id": "none", "name": "OGG1:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_5636006", "map_id": "CHEBI:29145", "name": "FapyG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10781817", "map_id": "none", "name": "ERCC2-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781803", "map_id": "none", "name": "TC-NER pre-incision complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10781814", "map_id": "none", "name": "TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10779347", "map_id": "none", "name": "ATM phosphorylates WHSC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779342", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:WHSC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779337", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:p-S102-WHSC1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10779385", "map_id": "none", "name": "ATM phosphorylates TP53BP1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779372", "map_id": "none", "name": "DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10779325", "map_id": "none", "name": "RNF8 and RNF168 ubiquitinate H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779300", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779322", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764711", "map_id": "none", "name": "Cleavage of dihydrouracil by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764708", "map_id": "none", "name": "NTHL1:DHU-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_30140", "map_id": "CHEBI:15901", "name": "DHU", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10779340", "map_id": "none", "name": "WHSC1 dimethylates histone H4 on lysine K21 at DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779251", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10779472", "map_id": "none", "name": "CHEK1 phosphorylates RAD51", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779467", "map_id": "P25454", "name": "RAD51", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YER095W", "map_id": "YER095W", "name": "RAD51", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10779470", "map_id": "P25454", "name": "phospho-RAD51", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10777660", "map_id": "none", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10777656", "map_id": "P39875", "name": "EXO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YOR033C", "map_id": "YOR033C", "name": "EXO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10777640", "map_id": "none", "name": "MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P14242", "map_id": "P14242", "name": "PMS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL082W", "map_id": "YNL082W", "name": "PMS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38920", "map_id": "P38920", "name": "MLH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR167W", "map_id": "YMR167W", "name": "MLH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03834", "map_id": "Q03834", "name": "MSH6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR097C", "map_id": "YDR097C", "name": "MSH6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10777658", "map_id": "none", "name": "EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P39875", "map_id": "P39875", "name": "EXO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763954", "map_id": "none", "name": "Formation of RAD50:MRE11 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10763950", "map_id": "P32829", "name": "MRE11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_981774", "map_id": "P12753", "name": "DNA repair protein RAD50", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10763952", "map_id": "none", "name": "RAD50:MRE11A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10777627", "map_id": "none", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10777623", "map_id": "none", "name": "MSH2:MSH6:ATP:DNA containing 1-2 base mismatch", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10777609", "map_id": "none", "name": "MLH1:PMS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10777625", "map_id": "none", "name": "MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10779284", "map_id": "none", "name": "PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779267", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:p-T4827-HERC2:PIAS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779281", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:PIAS4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781725", "map_id": "none", "name": "ERCC6 binds stalled RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781721", "map_id": "P40352", "name": "RAD26", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10781713", "map_id": "none", "name": "Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10781723", "map_id": "none", "name": "Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10779259", "map_id": "none", "name": "RNF8 binds phosphorylated MDC1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779220", "map_id": "none", "name": "RNF8:Zn2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779255", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779257", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764718", "map_id": "none", "name": "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764715", "map_id": "none", "name": "NTHL1:FapyA-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_5637659", "map_id": "CHEBI:27983", "name": "FapyA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10779296", "map_id": "none", "name": "HERC2 facilitates UBE2N:UBE2V2 binding to RNF8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779290", "map_id": "none", "name": "UBE2N:UBE2V2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779294", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:PIAS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778520", "map_id": "none", "name": "USP1 autocleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778480", "map_id": "Q99247", "name": "DUF1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10778517", "map_id": "none", "name": "Homologues of USP1(672-785)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10778505", "map_id": "none", "name": "Homologues of USP1(1-671)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10779349", "map_id": "none", "name": "KDM4A,B bind H4K20Me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779253", "map_id": "none", "name": "KDM4A,B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781843", "map_id": "none", "name": "5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781838", "map_id": "none", "name": "TC-NER incision complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781711", "map_id": "none", "name": "RNA Pol II initiates transcription from damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10762310", "map_id": "none", "name": "RNA Polymerase II holoenzyme complex (unphosphorylated)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_5688114", "map_id": "none", "name": "Distorted dsDNA", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10781709", "map_id": "none", "name": "Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781209", "map_id": "none", "name": "ATM phosphorylates MDC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781206", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:MDC1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779335", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764732", "map_id": "none", "name": "Excision of 8-oxoguanine by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764727", "map_id": "none", "name": "OGG1:(8oxoG:Cyt)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110242", "map_id": "CHEBI:44605", "name": "8oxoG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10781219", "map_id": "none", "name": "ATM phosphorylates histone H2AFX on S139 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781216", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779442", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781716", "map_id": "none", "name": "Active RNA Pol II complex transcribes lesion-containing DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_6781829", "map_id": "CHEBI:17972", "name": "ribonucleoside triphosphate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10788944", "map_id": "none", "name": "OGG1beta translocates to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788940", "map_id": "P53397", "name": "OGG1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10788942", "map_id": "P53397", "name": "OGG1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10777662", "map_id": "none", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10777647", "map_id": "none", "name": "MSH2:MSH6:ADP:DNA containing 1-2 base mismatch", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781224", "map_id": "none", "name": "ATM phosphorylates NBN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781211", "map_id": "none", "name": "DNA DSBs:MRN:p-S1981,Ac-K3016-ATM:KAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779232", "map_id": "none", "name": "DNA DSB:p-MRN:p-S1981,Ac-K3016-ATM:KAT5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10779344", "map_id": "none", "name": "WHSC1 binds DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776856", "map_id": "P46995", "name": "SET2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10779366", "map_id": "none", "name": "RNF8 and RNF168 ubiquitinate KDM4A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779363", "map_id": "none", "name": "K48PolyUb-KDM4A,B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781240", "map_id": "none", "name": "ATM recognizes H2AFX-Nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779432", "map_id": "none", "name": "p-Y142-H2AFX-Nucleosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764697", "map_id": "none", "name": "Cleavage of thymine glycol by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764692", "map_id": "none", "name": "NTHL1:Tg-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110223", "map_id": "CHEBI:29128", "name": "Tg", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10781214", "map_id": "none", "name": "MRN activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10764681", "map_id": "none", "name": "Cleavage of uracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764674", "map_id": "none", "name": "UNG-1:(Ura:Gua)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P12887", "map_id": "P12887", "name": "UNG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML021C", "map_id": "YML021C", "name": "UNG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764678", "map_id": "none", "name": "UNG-1:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10777649", "map_id": "none", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5358514", "map_id": "none", "name": "DNA containing mismatch or 1-2 base IDL", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10777645", "map_id": "none", "name": "MSH2:MSH6:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10777799", "map_id": "none", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10777607", "map_id": "P14242", "name": "PMS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10777602", "map_id": "P38920", "name": "MLH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10779382", "map_id": "none", "name": "PPP5C dephosphorylates TP53BP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779379", "map_id": "P53043", "name": "PPT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YGR123C", "map_id": "YGR123C", "name": "PPT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781806", "map_id": "none", "name": "UVSSA:USP7 deubiquitinates ERCC6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781797", "map_id": "none", "name": "Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781850", "map_id": "none", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781845", "map_id": "none", "name": "TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10777797", "map_id": "none", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10777619", "map_id": "Q03834", "name": "MSH6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10777643", "map_id": "none", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10789082", "map_id": "none", "name": "ERCC3-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781825", "map_id": "none", "name": "TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10779270", "map_id": "none", "name": "ATM phosphorylates HERC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779263", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:HERC2:PIAS4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10777651", "map_id": "none", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5358610", "map_id": "none", "name": "DNA containing single strand nick (5' phosphate, 3' hydroxyl)", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_109966", "map_id": "none", "name": "Repaired double-stranded DNA", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10778493", "map_id": "none", "name": "USP1:WDR48 binds monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778484", "map_id": "none", "name": "MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764688", "map_id": "none", "name": "Cleavage of 5-hydroxyluracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764685", "map_id": "none", "name": "UNG-1:5-OHU-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110216", "map_id": "CHEBI:29115", "name": "5-OHU", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10777996", "map_id": "none", "name": "HDAC6 deacetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10777993", "map_id": "none", "name": "acetylated microtubule", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10777457", "map_id": "P53973", "name": "HDA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YNL021W", "map_id": "YNL021W", "name": "HDA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10778225", "map_id": "none", "name": "RAB11A:GTP-containing Golgi vesicles recruit RAB3IP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13949", "compartment_display": "Golgi-associated vesicle membrane" }, { "id": "species_10778216", "map_id": "none", "name": "RAB11A:GTP:Golgi derived vesicle", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13949", "compartment_display": "Golgi-associated vesicle membrane", "complex": "true" }, { "id": "P51996", "map_id": "P51996", "name": "YPT32", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL210W", "map_id": "YGL210W", "name": "YPT32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38555", "map_id": "P38555", "name": "YPT31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER031C", "map_id": "YER031C", "name": "YPT31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10778223", "map_id": "none", "name": "RAB3IP:RAB11A:GTP:Golgi-derived vesicle", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13949", "compartment_display": "Golgi-associated vesicle membrane", "complex": "true" }, { "id": "P17065", "map_id": "P17065", "name": "SEC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787471", "map_id": "none", "name": "F1Fo ATP synthase dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10787469", "map_id": "none", "name": "F1Fo ATP synthase dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10761323", "map_id": "none", "name": "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29512", "map_id": "CHEBI:57634", "name": "Fru(6)P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_30537", "map_id": "CHEBI:58225", "name": "G6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761318", "map_id": "none", "name": "GPI dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10778180", "map_id": "none", "name": "PRDX1 overoxidizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29408", "map_id": "CHEBI:16240", "name": "H2O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10778172", "map_id": "none", "name": "PRDX1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10778177", "map_id": "none", "name": "HOOS-C52-PRDX1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10762082", "map_id": "none", "name": "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111745", "map_id": "CHEBI:58297", "name": "GSSG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10762079", "map_id": "none", "name": "GSR-2:FAD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P41921", "map_id": "P41921", "name": "GLR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL091W", "map_id": "YPL091W", "name": "GLR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761172", "map_id": "none", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_31467", "map_id": "CHEBI:16938", "name": "D-Glucono-1,5-lactone 6-phosphate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761169", "map_id": "none", "name": "G6PD dimer and tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P11412", "map_id": "P11412", "name": "ZWF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL241C", "map_id": "YNL241C", "name": "ZWF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771975", "map_id": "none", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_915149", "map_id": "CHEBI:59092", "name": "(GlcNAc)2 (Man)9", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_964740", "map_id": "CHEBI:59087", "name": "(GlcNAc)2 (Man)5 (Asn)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_964752", "map_id": "CHEBI:4208", "name": "Man", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10771968", "map_id": "Q12205", "name": "MNL2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "YLR057W", "map_id": "YLR057W", "name": "MNL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10777597", "map_id": "none", "name": "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10777577", "map_id": "P32324", "name": "EFT2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10777564", "map_id": "P32324", "name": "EFT2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10777594", "map_id": "none", "name": "DPH1:DPH2:DPH3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32461", "map_id": "P32461", "name": "DPH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL191W", "map_id": "YKL191W", "name": "DPH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40487", "map_id": "P40487", "name": "DPH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL103W", "map_id": "YIL103W", "name": "DPH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3E840", "map_id": "Q3E840", "name": "KTI11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL071W-A", "map_id": "YBL071W-A", "name": "KTI11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769136", "map_id": "none", "name": "Association of CCT/TriC with sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769132", "map_id": "none", "name": "CCT/TRiC:ADP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P39079", "map_id": "P39079", "name": "CCT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR188W", "map_id": "YDR188W", "name": "CCT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P42943", "map_id": "P42943", "name": "CCT7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL111W", "map_id": "YJL111W", "name": "CCT7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39078", "map_id": "P39078", "name": "CCT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL143W", "map_id": "YDL143W", "name": "CCT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39077", "map_id": "P39077", "name": "CCT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL014W", "map_id": "YJL014W", "name": "CCT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P12612", "map_id": "P12612", "name": "TCP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR212W", "map_id": "YDR212W", "name": "TCP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40413", "map_id": "P40413", "name": "CCT5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR064W", "map_id": "YJR064W", "name": "CCT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10769134", "map_id": "none", "name": "CCT/TRiC:ADP:Sphingosine kinase 1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q06147", "map_id": "Q06147", "name": "LCB5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784720", "map_id": "none", "name": "NSF ATPase activity dissociates cis-SNARE at cis-Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10784715", "map_id": "none", "name": "cis-SNARE:3xSNAP:NSF hexamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "P25385", "map_id": "P25385", "name": "BOS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR078C", "map_id": "YLR078C", "name": "BOS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22804", "map_id": "P22804", "name": "BET1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL004C", "map_id": "YIL004C", "name": "BET1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36015", "map_id": "P36015", "name": "YKT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL196C", "map_id": "YKL196C", "name": "YKT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P43682", "map_id": "P43682", "name": "SFT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL006C-A", "map_id": "YKL006C-A", "name": "SFT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38736", "map_id": "P38736", "name": "GOS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHL031C", "map_id": "YHL031C", "name": "GOS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784697", "map_id": "none", "name": "Homologues of BET1L", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10784688", "map_id": "P38736", "name": "GOS1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10784699", "map_id": "Q01590", "name": "SED5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10784683", "map_id": "P36015", "name": "YKT6", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10784703", "map_id": "P25385", "name": "BOS1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10784707", "map_id": "P22804", "name": "BET1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10776520", "map_id": "none", "name": "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_4419987", "map_id": "CHEBI:17407", "name": "E,E-FPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_191362", "map_id": "CHEBI:16584", "name": "IPPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_4419982", "map_id": "CHEBI:37531", "name": "pPPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10776517", "map_id": "none", "name": "DHDDS:NUS1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q12063", "map_id": "Q12063", "name": "NUS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL193W", "map_id": "YDL193W", "name": "NUS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P35196", "map_id": "P35196", "name": "RER2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR002C", "map_id": "YBR002C", "name": "RER2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765434", "map_id": "none", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10765430", "map_id": "P32324", "name": "EFT2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10765432", "map_id": "none", "name": "eEF2:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10774887", "map_id": "none", "name": "PIAS4 SUMOylates TP53BP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10774872", "map_id": "none", "name": "SUMO1:TP53BP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10774884", "map_id": "none", "name": "Homologues of PIAS4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781067", "map_id": "none", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10766133", "map_id": "none", "name": "K63-Ub", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10760639", "map_id": "P43588", "name": "RPN11", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10786777", "map_id": "none", "name": "RGGT geranylgeranylates RAB proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10786641", "map_id": "none", "name": "RGGT:CHMs:RABs:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_1131164", "map_id": "CHEBI:48861", "name": "geranylgeranyl diphosphate", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "P36019", "map_id": "P36019", "name": "YPT53", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL093W", "map_id": "YNL093W", "name": "YPT53", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10786772", "map_id": "none", "name": "CHMs:GGC-RABs:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786774", "map_id": "none", "name": "RGGTA:RGGTB:GGPP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10787662", "map_id": "none", "name": "PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10787654", "map_id": "none", "name": "PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "P35056", "map_id": "P35056", "name": "phospho-PEX5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "phospho-PEX5", "map_id": "phospho-PEX5", "name": "phospho-PEX5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53112", "map_id": "P53112", "name": "PEX14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PEX14", "map_id": "PEX14", "name": "PEX14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P80667", "map_id": "P80667", "name": "PEX13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "PEX13", "map_id": "PEX13", "name": "PEX13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04370", "map_id": "Q04370", "name": "PEX12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR026C", "map_id": "YMR026C", "name": "PEX12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05568", "map_id": "Q05568", "name": "PEX10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR265W", "map_id": "YDR265W", "name": "PEX10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787658", "map_id": "none", "name": "Ub:UBE2D1,2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10787660", "map_id": "none", "name": "PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10765525", "map_id": "none", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8855663", "map_id": "none", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449229", "map_id": "CHEBI:15809", "name": "DOLP-Man", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_162872", "map_id": "CHEBI:16214", "name": "dolichyl phosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8855667", "map_id": "CHEBI:53058", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10765522", "map_id": "P38211", "name": "GPI18", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YBR004C", "map_id": "YBR004C", "name": "GPI18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770358", "map_id": "none", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_449703", "map_id": "CHEBI:15784", "name": "AcGlcN6P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_532204", "map_id": "CHEBI:7125", "name": "AcGlcN1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10770355", "map_id": "P38628", "name": "PCM1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YEL058W", "map_id": "YEL058W", "name": "PCM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768034", "map_id": "none", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767990", "map_id": "none", "name": "Dhp-K50-EIF5A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P19211", "map_id": "P19211", "name": "ANB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR047C", "map_id": "YJR047C", "name": "ANB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P23301", "map_id": "P23301", "name": "HYP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL034W", "map_id": "YEL034W", "name": "HYP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768024", "map_id": "none", "name": "Hyp-K50-EIF5A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10768031", "map_id": "none", "name": "DOHH:Fe++", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P47120", "map_id": "P47120", "name": "LIA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR070C", "map_id": "YJR070C", "name": "LIA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787059", "map_id": "none", "name": "METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775766", "map_id": "P10592", "name": "SSA2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10787051", "map_id": "P10592", "name": "SSA2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10787056", "map_id": "P53970", "name": "EFM6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YNL024C", "map_id": "YNL024C", "name": "EFM6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785932", "map_id": "none", "name": "OTULIN,USP5 cleaves UBB yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10785930", "map_id": "none", "name": "Homologues of UBB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10760584", "map_id": "none", "name": "Homologues of UBB(153-228)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10760576", "map_id": "none", "name": "Homologues of UBB(77-152)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10760568", "map_id": "none", "name": "Homologues of RPS27A(1-76)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10780500", "map_id": "P38237", "name": "UBP14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10776349", "map_id": "none", "name": "SUMOylation of DDX5 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776339", "map_id": "P24783", "name": "DBP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YNL112W", "map_id": "YNL112W", "name": "DBP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776347", "map_id": "none", "name": "SUMO1:DDX5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P24783", "map_id": "P24783", "name": "DBP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772580", "map_id": "none", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10772576", "map_id": "none", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_927893", "compartment_display": "endoplasmic reticulum quality control compartment", "complex": "true" }, { "id": "species_10772578", "map_id": "none", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:60627", "map_id": "CHEBI:60627", "name": "CHEBI:60627", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:60629", "map_id": "CHEBI:60629", "name": "CHEBI:60629", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:60628", "map_id": "CHEBI:60628", "name": "CHEBI:60628", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770374", "map_id": "none", "name": "Addition of a second glucose to the N-glycan precursor by ALG8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_449649", "map_id": "CHEBI:59081", "name": "(Glc)1 (GlcNAc)2 (Man)9 (PP-Dol)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_532542", "map_id": "CHEBI:15812", "name": "DbGP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449311", "map_id": "CHEBI:16214", "name": "DOLP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449638", "map_id": "CHEBI:53020", "name": "(Glc)2 (GlcNAc)2 (Man)9 (PP-Dol)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10770371", "map_id": "P40351", "name": "ALG8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YOR067C", "map_id": "YOR067C", "name": "ALG8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10776364", "map_id": "none", "name": "SUMOylation of PIAS4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776362", "map_id": "none", "name": "SUMO1:PIAS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781491", "map_id": "none", "name": "NSF ATPase activity dissociates cis-SNARE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10781486", "map_id": "none", "name": "cis-SNARE:NSF hexamer:3xSNAP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "Q12241", "map_id": "Q12241", "name": "VAM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR106W", "map_id": "YOR106W", "name": "VAM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32854", "map_id": "P32854", "name": "PEP12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR036W", "map_id": "YOR036W", "name": "PEP12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10781458", "map_id": "P22213", "name": "SLY1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10781451", "map_id": "P22804", "name": "BET1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "species_10781474", "map_id": "none", "name": "STX5,17", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10781482", "map_id": "none", "name": "ER-to-ERGIC v-SNARES", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10781453", "map_id": "P25385", "name": "BOS1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "reaction_10776337", "map_id": "none", "name": "SUMOylation of DDX17 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776327", "map_id": "P24783", "name": "DBP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10776335", "map_id": "none", "name": "SUMO1:DDX17", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10785870", "map_id": "none", "name": "UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10772385", "map_id": "P22515", "name": "UBA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10785770", "map_id": "none", "name": "UBA1:ubiquitin adenylate", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10768010", "map_id": "none", "name": "DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_204628", "map_id": "CHEBI:15725", "name": "1,3-diaminopropane", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10768000", "map_id": "none", "name": "EIF5A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10768007", "map_id": "none", "name": "DHPS tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38791", "map_id": "P38791", "name": "DYS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR068W", "map_id": "YHR068W", "name": "DYS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770366", "map_id": "none", "name": "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_449298", "map_id": "CHEBI:53022", "name": "(GlcNAc)2 (Man)5 (PP-Dol)1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449315", "map_id": "CHEBI:53023", "name": "(GlcNAc)2 (Man)6 (PP-Dol)1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10770363", "map_id": "P38179", "name": "ALG3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YBL082C", "map_id": "YBL082C", "name": "ALG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10762154", "map_id": "none", "name": "PPA1 hydrolyzes pyrophosphate to orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762151", "map_id": "none", "name": "PPA1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P28239", "map_id": "P28239", "name": "PPA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR267W", "map_id": "YMR267W", "name": "PPA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00817", "map_id": "P00817", "name": "IPP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR011C", "map_id": "YBR011C", "name": "IPP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763035", "map_id": "none", "name": "eIF5B:GTP is hydrolyzed and released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10763029", "map_id": "none", "name": "80S:Met-tRNAi:mRNA:eIF5B:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P10622", "map_id": "P10622", "name": "RPP1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL130W", "map_id": "YDL130W", "name": "RPP1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CX84", "map_id": "P0CX84", "name": "RPL35A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPL35A", "map_id": "RPL35A", "name": "RPL35A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CX41", "map_id": "P0CX41", "name": "RPL23A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPL23A", "map_id": "RPL23A", "name": "RPL23A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38754", "map_id": "P38754", "name": "RPL14B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPL14B", "map_id": "RPL14B", "name": "RPL14B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14455", "map_id": "O14455", "name": "RPL36B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPL36B", "map_id": "RPL36B", "name": "RPL36B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CX54", "map_id": "P0CX54", "name": "RPL12B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPL12B", "map_id": "RPL12B", "name": "RPL12B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P51401", "map_id": "P51401", "name": "RPL9B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPL9B", "map_id": "RPL9B", "name": "RPL9B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CX46", "map_id": "P0CX46", "name": "RPL2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPL2B", "map_id": "RPL2B", "name": "RPL2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02753", "map_id": "Q02753", "name": "RPL21A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPL21A", "map_id": "RPL21A", "name": "RPL21A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P29453", "map_id": "P29453", "name": "RPL8B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPL8B", "map_id": "RPL8B", "name": "RPL8B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P49167", "map_id": "P49167", "name": "RPL38", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPL38", "map_id": "RPL38", "name": "RPL38", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CX42", "map_id": "P0CX42", "name": "RPL23B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPL23B", "map_id": "RPL23B", "name": "RPL23B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P10664", "map_id": "P10664", "name": "RPL4A", "type": 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10765400", "map_id": "none", "name": "Homologues of EEF1A1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10787088", "map_id": "none", "name": "Homologues of Me3K318-EEF1A1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10787093", "map_id": "P40516", "name": "EFM4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YIL064W", "map_id": "YIL064W", "name": "EFM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10776706", "map_id": "none", "name": "SUMOylation of TOP2A with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776696", "map_id": "P06786", "name": "TOP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YNL088W", "map_id": "YNL088W", "name": "TOP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776704", "map_id": "none", "name": "SUMO1:TOP2A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P06786", "map_id": "P06786", "name": "TOP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10777327", "map_id": "none", "name": "RANBP2 SUMOylates MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10763942", "map_id": "none", "name": "Nuclear Pore Complex (NPC)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "P40066", "map_id": "P40066", "name": "GLE2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER107C", "map_id": "YER107C", "name": "GLE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02455", "map_id": "Q02455", "name": "MLP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR095W", "map_id": "YKR095W", "name": "MLP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36161", "map_id": "P36161", "name": "NUP133", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR082W", "map_id": "YKR082W", "name": "NUP133", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P52891", "map_id": "P52891", "name": "NUP84", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL116W", "map_id": "YDL116W", "name": "NUP84", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38181", "map_id": "P38181", "name": "NUP170", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL079W", "map_id": "YBL079W", "name": "NUP170", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53011", "map_id": "P53011", "name": "SEH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL100W", "map_id": "YGL100W", "name": "SEH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P20676", "map_id": "P20676", "name": "NUP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR098C", "map_id": "YOR098C", "name": "NUP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47054", "map_id": "P47054", "name": "NUP192", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL039C", "map_id": "YJL039C", "name": "NUP192", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02630", "map_id": "Q02630", "name": "NUP116", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR047C", "map_id": "YMR047C", "name": "NUP116", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40368", "map_id": "P40368", "name": "NUP82", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL061W", "map_id": "YJL061W", "name": "NUP82", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04491", "map_id": "Q04491", "name": "SEC13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR208W", "map_id": "YLR208W", "name": "SEC13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05166", "map_id": "Q05166", "name": "ASM4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL088C", "map_id": "YDL088C", "name": "ASM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P46673", "map_id": "P46673", "name": "NUP85", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR042W", "map_id": "YJR042W", "name": "NUP85", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P48837", "map_id": "P48837", "name": "NUP57", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR119C", "map_id": "YGR119C", "name": "NUP57", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P34077", "map_id": "P34077", "name": "NIC96", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFR002W", "map_id": "YFR002W", "name": "NIC96", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P14907", "map_id": "P14907", "name": "NSP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL041W", "map_id": "YJL041W", "name": "NSP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P52593", "map_id": "P52593", "name": "NUP188", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML103C", "map_id": "YML103C", "name": "NUP188", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P35729", "map_id": "P35729", "name": "NUP120", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL057C", "map_id": "YKL057C", "name": "NUP120", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32500", "map_id": "P32500", "name": "NDC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML031W", "map_id": "YML031W", "name": "NDC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41920", "map_id": "P41920", "name": "YRB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR002W", "map_id": "YDR002W", "name": "YRB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10776585", "map_id": "none", "name": "SUMOylation of NOP58 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776574", "map_id": "Q12499", "name": "NOP58", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10776583", "map_id": "none", "name": "2SUMO1:NOP58", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10784643", "map_id": "none", "name": "ARFGAPs stimulate ARF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10784546", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "P25386", "map_id": "P25386", "name": "USO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL058W", "map_id": "YDL058W", "name": "USO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784640", "map_id": "none", "name": "RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_432051", "compartment_display": "transport vesicle", "complex": "true" }, { "id": "reaction_10770382", "map_id": "none", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_449299", "map_id": "CHEBI:16214", "name": "DOLP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_162756", "map_id": "CHEBI:16264", "name": "UDP-GlcNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_109402", "map_id": "CHEBI:57865", "name": "UMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_449222", "map_id": "CHEBI:18278", "name": "GlcNAcDOLDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10770379", "map_id": "P07286", "name": "ALG7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YBR243C", "map_id": "YBR243C", "name": "ALG7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10776642", "map_id": "none", "name": "RANBP2 SUMOylates HDAC4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776632", "map_id": "P53973", "name": "HDA1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10776640", "map_id": "none", "name": "SUMO1:HDAC4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P53973", "map_id": "P53973", "name": "HDA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765517", "map_id": "none", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8855657", "map_id": "CHEBI:15935", "name": "N-acetylglucosaminyl-PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_29416", "map_id": "CHEBI:15366", "name": "CH3COO-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8855661", "map_id": "CHEBI:24275", "name": "glucosaminyl-PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10765514", "map_id": "P23797", "name": "GPI12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YMR281W", "map_id": "YMR281W", "name": "GPI12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770615", "map_id": "none", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10770612", "map_id": "none", "name": "PPA2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10765380", "map_id": "none", "name": "Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10765355", "map_id": "P26784", "name": "phospho-RPL16A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10765376", "map_id": "none", "name": "43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P07260", "map_id": "P07260", "name": "CDC33", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL139C", "map_id": "YOL139C", "name": "CDC33", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32481", "map_id": "P32481", "name": "GCD11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "GCD11", "map_id": "GCD11", "name": "GCD11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04067", "map_id": "Q04067", "name": "phospho-TIF35", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR429C", "map_id": "YDR429C", "name": "phospho-TIF35", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38760", "map_id": "P38760", "name": "MIP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR015W", "map_id": "YHR015W", "name": "MIP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38249", "map_id": "P38249", "name": "RPG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR079C", "map_id": "YBR079C", "name": "RPG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P04147", "map_id": "P04147", "name": "PAB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER165W", "map_id": "YER165W", "name": "PAB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P09064", "map_id": "P09064", "name": "SUI3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SUI3", "map_id": "SUI3", "name": "SUI3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P06103", "map_id": "P06103", "name": "PRT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR361C", "map_id": "YOR361C", "name": "PRT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39684", "map_id": "P39684", "name": "PES4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFR023W", "map_id": "YFR023W", "name": "PES4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P20459", "map_id": "P20459", "name": "phospho-SUI2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "phospho-SUI2", "map_id": "phospho-SUI2", "name": "phospho-SUI2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40217", "map_id": "P40217", "name": "TIF34", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR146C", "map_id": "YMR146C", "name": "TIF34", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P10081", "map_id": "P10081", "name": "TIF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR059W", "map_id": "YKR059W", "name": "TIF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32497", "map_id": "P32497", "name": "NIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR309C", "map_id": "YMR309C", "name": "NIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05775", "map_id": "Q05775", "name": "HCR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR192C", "map_id": "YLR192C", "name": "HCR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38912", "map_id": "P38912", "name": "TIF11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR260C", "map_id": "YMR260C", "name": "TIF11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765378", "map_id": "none", "name": "phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10776408", "map_id": "none", "name": "SUMOylation of UBE2I with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776406", "map_id": "none", "name": "SUMO1:K14-UBE2I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10787608", "map_id": "none", "name": "AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787593", "map_id": "none", "name": "NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q12395", "map_id": "Q12395", "name": "DCN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR128W", "map_id": "YLR128W", "name": "DCN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03919", "map_id": "Q03919", "name": "RUB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR139C", "map_id": "YDR139C", "name": "RUB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787605", "map_id": "none", "name": "NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10787548", "map_id": "P52491", "name": "UBC12", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773656", "map_id": "none", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10773652", "map_id": "none", "name": "ribosome:mRNA:polypeptide+signal", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10773650", "map_id": "none", "name": "Signal Recognition Particle", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38687", "map_id": "P38687", "name": "SRP68", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL243W", "map_id": "YPL243W", "name": "SRP68", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32342", "map_id": "P32342", "name": "SRP21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL122C", "map_id": "YKL122C", "name": "SRP21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38688", "map_id": "P38688", "name": "SRP72", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL210C", "map_id": "YPL210C", "name": "SRP72", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P29478", "map_id": "P29478", "name": "SEC65", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML105C", "map_id": "YML105C", "name": "SEC65", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P20424", "map_id": "P20424", "name": "SRP54", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR088C", "map_id": "YPR088C", "name": "SRP54", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10773654", "map_id": "none", "name": "SRP:polypeptide+signal:ribosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10777561", "map_id": "none", "name": "DPH6 ligates ammonium to diphthine-EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10777553", "map_id": "P32324", "name": "EFT2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10777558", "map_id": "Q12429", "name": "DPH6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YLR143W", "map_id": "YLR143W", "name": "DPH6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786576", "map_id": "none", "name": "RGGT binds the RAB-binding subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10786568", "map_id": "none", "name": "RABGGTA:RABGGTB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786574", "map_id": "none", "name": "RABGGTA:RABGGTB:CHMs:GGPP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10775215", "map_id": "none", "name": "PIAS3 SUMOylates MITF with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775197", "map_id": "P38165", "name": "RTG3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YBL103C", "map_id": "YBL103C", "name": "RTG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10775206", "map_id": "none", "name": "2SUMO1:MITF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P38165", "map_id": "P38165", "name": "RTG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10775212", "map_id": "none", "name": "Homologues of PIAS3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10762699", "map_id": "none", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762638", "map_id": "none", "name": "EIF2S1:EIF2S2:EIF2S3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10762640", "map_id": "none", "name": "eIF2:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10787672", "map_id": "none", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10772640", "map_id": "none", "name": "UBE2D1,2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10787669", "map_id": "none", "name": "PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10770406", "map_id": "none", "name": "DOLPP1 dephosphorylates DOLDP to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_449744", "map_id": "CHEBI:15750", "name": "DOLDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10770403", "map_id": "P53223", "name": "CAX4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YGR036C", "map_id": "YGR036C", "name": "CAX4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10762732", "map_id": "none", "name": "Formation of eIF2:GDP:eIF2B intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762728", "map_id": "none", "name": "eIF2B subunits complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P09032", "map_id": "P09032", "name": "GCD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR260W", "map_id": "YOR260W", "name": "GCD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32502", "map_id": "P32502", "name": "GCD7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR291C", "map_id": "YLR291C", "name": "GCD7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P12754", "map_id": "P12754", "name": "GCD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR083C", "map_id": "YGR083C", "name": "GCD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P14741", "map_id": "P14741", "name": "GCN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR026C", "map_id": "YKR026C", "name": "GCN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32501", "map_id": "P32501", "name": "GCD6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR211W", "map_id": "YDR211W", "name": "GCD6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10762689", "map_id": "none", "name": "eIF2:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10762730", "map_id": "none", "name": "eIF2:GDP: eIF2B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10776691", "map_id": "none", "name": "SUMOylation of HDAC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776117", "map_id": "Q12214", "name": "HOS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YPR068C", "map_id": "YPR068C", "name": "HOS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776689", "map_id": "none", "name": "SUMO1:HDAC2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q12214", "map_id": "Q12214", "name": "HOS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785332", "map_id": "none", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10781520", "map_id": "none", "name": "RAB1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10785328", "map_id": "P43570", "name": "GYP8", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "YFL027C", "map_id": "YFL027C", "name": "GYP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785330", "map_id": "none", "name": "RAB1:GTP:TBC1D20", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "P43570", "map_id": "P43570", "name": "GYP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770593", "map_id": "none", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_449701", "map_id": "CHEBI:15873", "name": "GlcN6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10770590", "map_id": "none", "name": "GFPT1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P14742", "map_id": "P14742", "name": "GFA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL104C", "map_id": "YKL104C", "name": "GFA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CF18", "map_id": "P0CF18", "name": "GFPT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR085W", "map_id": "YMR085W", "name": "GFPT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10776528", "map_id": "none", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_4419981", "map_id": "CHEBI:67132", "name": "pPNOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449221", "map_id": "CHEBI:16091", "name": "DCHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10776525", "map_id": "P40526", "name": "DFG10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YIL049W", "map_id": "YIL049W", "name": "DFG10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785861", "map_id": "none", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10785822", "map_id": "none", "name": "Ub-Cys632-UBA1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10763043", "map_id": "none", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10763041", "map_id": "none", "name": "40S:eIF3:eIF1A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10762642", "map_id": "none", "name": "ternary complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10762644", "map_id": "none", "name": "43S complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10776600", "map_id": "none", "name": "RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776590", "map_id": "P38996", "name": "NAB3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YPL190C", "map_id": "YPL190C", "name": "NAB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776598", "map_id": "none", "name": "SUMO1:HNRNPC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P38996", "map_id": "P38996", "name": "NAB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770224", "map_id": "none", "name": "ZnT5 transports zinc into secretory granules in pancreatic beta cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen" }, { "id": "species_29426", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_216785", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen", "complex": "false" }, { "id": "species_10770221", "map_id": "Q03455", "name": "MSC2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "false" }, { "id": "YDR205W", "map_id": "YDR205W", "name": "MSC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770603", "map_id": "none", "name": "Acetylation of glucosamine 6-phosphate to GlcNAc6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770600", "map_id": "none", "name": "2xGNPNAT1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P43577", "map_id": "P43577", "name": "GNA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFL017C", "map_id": "YFL017C", "name": "GNA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786570", "map_id": "none", "name": "RABGGTA and RABGGTB bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10786564", "map_id": "Q00618", "name": "BET4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10786566", "map_id": "P20133", "name": "BET2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10762701", "map_id": "none", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_72393", "map_id": "none", "name": "Met-tRNAi", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10781400", "map_id": "none", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle" }, { "id": "species_10781393", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle", "complex": "true" }, { "id": "P38968", "map_id": "P38968", "name": "SEC31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL195W", "map_id": "YDL195W", "name": "SEC31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12204", "map_id": "Q12204", "name": "SEC23IP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR022C", "map_id": "YOR022C", "name": "SEC23IP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10781397", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle", "complex": "true" }, { "id": "reaction_10776398", "map_id": "none", "name": "UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776376", "map_id": "none", "name": "Homologues of FOXL2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P25364", "map_id": "P25364", "name": "HCM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCR065W", "map_id": "YCR065W", "name": "HCM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40466", "map_id": "P40466", "name": "FKH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL131C", "map_id": "YIL131C", "name": "FKH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776393", "map_id": "none", "name": "3SUMO1:FOXL2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776395", "map_id": "none", "name": "UBE2I,PIAS1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10770449", "map_id": "none", "name": "Synthesis of dolichyl-phosphate-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_532214", "map_id": "CHEBI:15812", "name": "DbGP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10770446", "map_id": "P40350", "name": "ALG5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YPL227C", "map_id": "YPL227C", "name": "ALG5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785688", "map_id": "none", "name": "UBA1 adenylates ubiquitin in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10785583", "map_id": "P22515", "name": "UBA1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10771977", "map_id": "none", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_964831", "map_id": "none", "name": "(GlcNAc)2 (Man)8 glycans", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10774770", "map_id": "none", "name": "SENP1,2,5 proteolytically process SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10774758", "map_id": "Q12306", "name": "SMT3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10774763", "map_id": "Q02724", "name": "ULP1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10776472", "map_id": "none", "name": "SUMOylation of HIPK2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776462", "map_id": "P14680", "name": "YAK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YJL141C", "map_id": "YJL141C", "name": "YAK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776470", "map_id": "none", "name": "SUMO1:HIPK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P14680", "map_id": "P14680", "name": "YAK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10782019", "map_id": "none", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6788753", "map_id": "CHEBI:86019", "name": "S-FARN-Cys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6788758", "map_id": "CHEBI:87167", "name": "S-FARN-CME", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10782016", "map_id": "none", "name": "ICMT:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P32584", "map_id": "P32584", "name": "STE14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR410C", "map_id": "YDR410C", "name": "STE14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785820", "map_id": "none", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10785690", "map_id": "none", "name": "E2 ubiquitin conjugating enzyme (UBA1 substrate)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10785768", "map_id": "none", "name": "Ub-Cys632-UBA1:ubiquitin adenylate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10785818", "map_id": "none", "name": "Ub:E2 (UBA1 substrate)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10770457", "map_id": "none", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_449312", "map_id": "CHEBI:59088", "name": "(GlcNAc)2 (Man)7 (PP-Dol)1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10770454", "map_id": "P53868", "name": "ALG9", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YNL219C", "map_id": "YNL219C", "name": "ALG9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787521", "map_id": "none", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10781029", "map_id": "none", "name": "UCHL3,SENP8:NEDD8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P35127", "map_id": "P35127", "name": "YUH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR099W", "map_id": "YJR099W", "name": "YUH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10781027", "map_id": "Q03919", "name": "RUB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10780910", "map_id": "P35127", "name": "YUH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10770459", "map_id": "none", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_449365", "map_id": "CHEBI:59091", "name": "(GlcNAc)2 (Man)8 (PP-Dol)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449371", "map_id": "CHEBI:37637", "name": "(GlcNAc)2 (Man)9 (PP-Dol)1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10765384", "map_id": "none", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10763018", "map_id": "none", "name": "60S ribosomal complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10765382", "map_id": "none", "name": "60s ribosomal complex lacking L13a subunit", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10762778", "map_id": "P26784", "name": "RPL16A", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10784442", "map_id": "none", "name": "Active ARF recruits coatomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10784393", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1:ARF:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10784440", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10781493", "map_id": "none", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle" }, { "id": "species_10767942", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13945", "compartment_display": "ER to Golgi transport vesicle membrane", "complex": "true" }, { "id": "reaction_10763039", "map_id": "none", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762624", "map_id": "P38912", "name": "TIF11", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10763020", "map_id": "none", "name": "80S ribosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10781528", "map_id": "none", "name": "CSNK1D phosphorylates SEC23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10781508", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10781512", "map_id": "P15303", "name": "phospho-SEC23", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10781437", "map_id": "none", "name": "p-SEC24", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10767811", "map_id": "none", "name": "SEC31A:SEC13:SEC23IP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10781514", "map_id": "none", "name": "COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10781525", "map_id": "P29295", "name": "HRR25", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "reaction_10765493", "map_id": "none", "name": "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8855656", "map_id": "CHEBI:53059", "name": "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8855664", "map_id": "none", "name": "mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10765490", "map_id": "Q04174", "name": "SMP3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YOR149C", "map_id": "YOR149C", "name": "SMP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770398", "map_id": "none", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10770395", "map_id": "P53730", "name": "ALG12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YNR030W", "map_id": "YNR030W", "name": "ALG12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765509", "map_id": "none", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10765506", "map_id": "P30777", "name": "GPI10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YGL142C", "map_id": "YGL142C", "name": "GPI10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785872", "map_id": "none", "name": "UBA1 conjugates ubiquitin to UBA1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10781420", "map_id": "none", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10767888", "map_id": "P15303", "name": "SEC23", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10781416", "map_id": "none", "name": "SEC24A,SEC24B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10781418", "map_id": "none", "name": "SEC24A,B:SEC23A:SEC22B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10787561", "map_id": "none", "name": "Transfer of NEDD8 to AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787550", "map_id": "none", "name": "AcM-UBE2M:NEDD8-UBA3:NAE1:NEDD8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q12059", "map_id": "Q12059", "name": "ULA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL003W", "map_id": "YPL003W", "name": "ULA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787558", "map_id": "none", "name": "NEDD8-AcM-UBE2M", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10787538", "map_id": "none", "name": "NEDD8-UBA3:NAE1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10785864", "map_id": "none", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10785692", "map_id": "none", "name": "Ub-Cys632-UBA1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10762691", "map_id": "none", "name": "Ribosomal scanning ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762680", "map_id": "none", "name": "48S complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_72617", "map_id": "none", "name": "eIF1", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10787567", "map_id": "none", "name": "Doubly neddylated UBA3:NAE1 binds AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787543", "map_id": "none", "name": "NEDD8-UBA3:NAE1:NEDD8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10786643", "map_id": "none", "name": "RGGT:CHM binds RABs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10786639", "map_id": "none", "name": "RABs:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10776610", "map_id": "none", "name": "SUMOylation of Histone H4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776608", "map_id": "none", "name": "SUMO1:HIST1H4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10771137", "map_id": "none", "name": "MPI isomerises Fru6P to Man6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_532562", "map_id": "CHEBI:17369", "name": "Man6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10771134", "map_id": "P29952", "name": "PMI40", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YER003C", "map_id": "YER003C", "name": "PMI40", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784375", "map_id": "none", "name": "RAB1:GTP recruits GBF1 to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10784371", "map_id": "none", "name": "USO1 homodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10784373", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10785905", "map_id": "none", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762487", "map_id": "none", "name": "Homologues of RPS27A(77-156)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10785902", "map_id": "none", "name": "UCHL3,USP7,USP9X", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10775006", "map_id": "none", "name": "SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10774426", "map_id": "none", "name": "Cohesin Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10774972", "map_id": "none", "name": "SUMOylated Cohesin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10775003", "map_id": "none", "name": "SMC5-SMC6 Complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P43124", "map_id": "P43124", "name": "NSE4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL105W", "map_id": "YDL105W", "name": "NSE4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12749", "map_id": "Q12749", "name": "SMC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR383W", "map_id": "YLR383W", "name": "SMC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38632", "map_id": "P38632", "name": "MMS21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL019C", "map_id": "YEL019C", "name": "MMS21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q07913", "map_id": "Q07913", "name": "NSE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR007W", "map_id": "YLR007W", "name": "NSE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08204", "map_id": "Q08204", "name": "SMC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL034W", "map_id": "YOL034W", "name": "SMC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781488", "map_id": "none", "name": "NSF and SNAPs bind cis-SNARE complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10781484", "map_id": "none", "name": "cis-SNARE", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10765501", "map_id": "none", "name": "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8855659", "map_id": "CHEBI:53056", "name": "mannose (a1-4) glucosaminyl-acyl-PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10765498", "map_id": "P36051", "name": "MCD4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YKL165C", "map_id": "YKL165C", "name": "MCD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781414", "map_id": "none", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10767882", "map_id": "none", "name": "GOSR2,STX5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10767884", "map_id": "P38810", "name": "SFB3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10767890", "map_id": "none", "name": "SEC23A:SEC24C,D:GOSR2,STX5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10787077", "map_id": "none", "name": "VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10777462", "map_id": "P25694", "name": "CDC48", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10787065", "map_id": "P25694", "name": "CDC48", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10787074", "map_id": "none", "name": "Homologues of VCPKMT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q12367", "map_id": "Q12367", "name": "RKM5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR137W", "map_id": "YLR137W", "name": "RKM5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53970", "map_id": "P53970", "name": "EFM6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763037", "map_id": "none", "name": "The 60S subunit joins the translation initiation complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762687", "map_id": "none", "name": "40S:Met-tRNAi:mRNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10763027", "map_id": "none", "name": "eIF5B:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10784389", "map_id": "none", "name": "GBF1 recruits ARF:GDP to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10784387", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1:ARF:GDP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10770434", "map_id": "none", "name": "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770431", "map_id": "none", "name": "2xUAP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P43123", "map_id": "P43123", "name": "QRI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL103C", "map_id": "YDL103C", "name": "QRI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10776442", "map_id": "none", "name": "SUMOylation of ING2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776424", "map_id": "none", "name": "Homologues of ING2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776440", "map_id": "none", "name": "SUMO1:ING2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10787541", "map_id": "none", "name": "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787528", "map_id": "none", "name": "UBA3:NAE1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10776669", "map_id": "none", "name": "SUMOylation of HDAC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10772638", "map_id": "Q12214", "name": "HOS1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10776667", "map_id": "none", "name": "2SUMO1:HDAC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10770467", "map_id": "none", "name": "Addition of the first mannose to the N-glycan precursor by ALG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_162860", "map_id": "CHEBI:15820", "name": "GDP-Man", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_449293", "map_id": "CHEBI:18341", "name": "N,N'-DCDOLDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449283", "map_id": "CHEBI:18396", "name": "MDCDD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10770464", "map_id": "P16661", "name": "ALG1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YBR110W", "map_id": "YBR110W", "name": "ALG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770441", "map_id": "none", "name": "Addition of a second mannose to the N-glycan precursor by ALG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_449737", "map_id": "CHEBI:59085", "name": "(GlcNAc)2 (Man)2 (PP-Dol)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10770438", "map_id": "P43636", "name": "ALG2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10784396", "map_id": "none", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "reaction_10776681", "map_id": "none", "name": "SUMOylation of PCNA with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760932", "map_id": "P15873", "name": "POL30", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10776679", "map_id": "none", "name": "SUMO1:PCNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10785219", "map_id": "none", "name": "TRiC/CCT binds unfolded G-protein beta subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10785211", "map_id": "P18851", "name": "STE4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YOR212W", "map_id": "YOR212W", "name": "STE4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785217", "map_id": "none", "name": "Unfolded G-protein beta subunit:CCT/TRiC:ADP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P18851", "map_id": "P18851", "name": "STE4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767954", "map_id": "none", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767946", "map_id": "none", "name": "SAR1B:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10767951", "map_id": "P11655", "name": "SEC12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YNR026C", "map_id": "YNR026C", "name": "SEC12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781575", "map_id": "none", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767892", "map_id": "none", "name": "COPII cargo receptors:SAR1B:GTP:SEC23:SEC24", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10765418", "map_id": "none", "name": "Formation of eEF1B complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10765409", "map_id": "P32471", "name": "EFB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YAL003W", "map_id": "YAL003W", "name": "EFB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765407", "map_id": "P32471", "name": "EFB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10765414", "map_id": "P29547", "name": "CAM1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YPL048W", "map_id": "YPL048W", "name": "CAM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765416", "map_id": "none", "name": "eEF1B complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32471", "map_id": "P32471", "name": "EFB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P29547", "map_id": "P29547", "name": "CAM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781018", "map_id": "none", "name": "UCHL1, UCHL3 cleave ubiquitin adducts", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10781013", "map_id": "none", "name": "UCHL1,UCHL3:Ub-Lys", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_1131871", "map_id": "CHEBI:32551", "name": "L-lysine", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10781015", "map_id": "none", "name": "UCHL1,UCHL3:Ub", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10776553", "map_id": "none", "name": "RANBP2 SUMOylates RANBP2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10776540", "map_id": "P41920", "name": "YRB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10776550", "map_id": "none", "name": "3SUMO1:RANBP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10763048", "map_id": "none", "name": "eIF2 activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10765425", "map_id": "none", "name": "Regeneration of eEF1A:GTP by eEF1B activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10765420", "map_id": "none", "name": "eEF1A:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10765402", "map_id": "none", "name": "eEF1A:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10765422", "map_id": "none", "name": "eEF1B:GDP exchange complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10781034", "map_id": "none", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10781025", "map_id": "none", "name": "UCHL3,SENP8:NEDD8(1-88)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10781031", "map_id": "Q03919", "name": "RUB1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10785911", "map_id": "none", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10785909", "map_id": "none", "name": "Homologues of UBA52(1-128)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10762930", "map_id": "none", "name": "Homologues of RPL40", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10785922", "map_id": "none", "name": "OTULIN,USP5 cleaves UBC yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10785919", "map_id": "none", "name": "Homologues of UBC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10760592", "map_id": "none", "name": "Homologues of UBC(229-304)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10760600", "map_id": "none", "name": "Homologues of UBC(305-380)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10760624", "map_id": "none", "name": "Homologues of UBC(533-608)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10760616", "map_id": "none", "name": "Homologues of UBC(457-532)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10760632", "map_id": "none", "name": "Homologues of UBC(609-684)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10760608", "map_id": "none", "name": "Homologues of UBC(381-456)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10770390", "map_id": "none", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_110094", "map_id": "CHEBI:58069", "name": "CDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10770387", "map_id": "P20048", "name": "SEC59", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YMR013C", "map_id": "YMR013C", "name": "SEC59", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787545", "map_id": "none", "name": "NEDD8-UBA3:NAE1 binds a second NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10781572", "map_id": "none", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10763045", "map_id": "none", "name": "Start codon recognition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762685", "map_id": "P38431", "name": "TIF5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YPR041W", "map_id": "YPR041W", "name": "TIF5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10762693", "map_id": "none", "name": "Formation of the cap-binding eIF4F complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762660", "map_id": "P07260", "name": "CDC33", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10762655", "map_id": "none", "name": "eIF4A subunits complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10762674", "map_id": "none", "name": "eIF4F", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10784717", "map_id": "none", "name": "cis-Golgi cis-SNARE binds NSF and SNAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10784713", "map_id": "none", "name": "cis-Golgi cis SNARE bundle", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10774816", "map_id": "none", "name": "Transfer of SUMO1 from E1 to UBE2I (UBC9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10785335", "map_id": "none", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "reaction_10770416", "map_id": "none", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_532531", "map_id": "CHEBI:35374", "name": "Man1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10770411", "map_id": "P07283", "name": "SEC53", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YFL045C", "map_id": "YFL045C", "name": "SEC53", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766770", "map_id": "none", "name": "MVD decarboxylates MVA5PP to IPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191403", "map_id": "CHEBI:15899", "name": "MVA5PP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766767", "map_id": "none", "name": "MVD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32377", "map_id": "P32377", "name": "MVD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNR043W", "map_id": "YNR043W", "name": "MVD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767972", "map_id": "none", "name": "SEC31:SEC13 and v-SNARE recruitment", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10767898", "map_id": "none", "name": "COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P48415", "map_id": "P48415", "name": "SEC16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL085W", "map_id": "YPL085W", "name": "SEC16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10767824", "map_id": "none", "name": "ER-to-ERGIC v-SNARES", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10767900", "map_id": "none", "name": "COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10768207", "map_id": "none", "name": "Exocyst complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10768198", "map_id": "P32844", "name": "SEC6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "false" }, { "id": "YIL068C", "map_id": "YIL068C", "name": "SEC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768183", "map_id": "P22224", "name": "SEC15", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YGL233W", "map_id": "YGL233W", "name": "SEC15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768188", "map_id": "P38261", "name": "EXO84", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YBR102C", "map_id": "YBR102C", "name": "EXO84", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768193", "map_id": "P33332", "name": "SEC3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YER008C", "map_id": "YER008C", "name": "SEC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768178", "map_id": "Q06245", "name": "SEC10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YLR166C", "map_id": "YLR166C", "name": "SEC10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768173", "map_id": "P89102", "name": "SEC5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YDR166C", "map_id": "YDR166C", "name": "SEC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768168", "map_id": "P32855", "name": "SEC8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YPR055W", "map_id": "YPR055W", "name": "SEC8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768203", "map_id": "P19658", "name": "EXO70", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YJL085W", "map_id": "YJL085W", "name": "EXO70", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768205", "map_id": "none", "name": "Exocyst Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P38261", "map_id": "P38261", "name": "EXO84", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P33332", "map_id": "P33332", "name": "SEC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P89102", "map_id": "P89102", "name": "SEC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32844", "map_id": "P32844", "name": "SEC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06245", "map_id": "Q06245", "name": "SEC10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22224", "map_id": "P22224", "name": "SEC15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32855", "map_id": "P32855", "name": "SEC8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P19658", "map_id": "P19658", "name": "EXO70", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10783818", "map_id": "none", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10783797", "map_id": "none", "name": "ETF1 dimer:eRF3:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P05453", "map_id": "P05453", "name": "SUP35", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SUP35", "map_id": "SUP35", "name": "SUP35", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P12385", "map_id": "P12385", "name": "SUP45", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SUP45", "map_id": "SUP45", "name": "SUP45", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10783804", "map_id": "none", "name": "Me-Q185-ETF1 dimer:eRF3:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10776658", "map_id": "none", "name": "PIAS2-2 SUMOylates SUZ12 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776647", "map_id": "P43554", "name": "SWP82", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YFL049W", "map_id": "YFL049W", "name": "SWP82", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776655", "map_id": "none", "name": "SUMO1:SUZ12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P43554", "map_id": "P43554", "name": "SWP82", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10774918", "map_id": "none", "name": "Homologues of PIAS2-1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10770424", "map_id": "none", "name": "Addition of the first glucose to the N-glycan precursor by ALG6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10770421", "map_id": "Q12001", "name": "ALG6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YOR002W", "map_id": "YOR002W", "name": "ALG6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10776717", "map_id": "none", "name": "SUMOylation of TOP2B with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776708", "map_id": "P06786", "name": "TOP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10776715", "map_id": "none", "name": "SUMO1:TOP2B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10776630", "map_id": "none", "name": "SUMOylation of XPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776620", "map_id": "Q06665", "name": "RAD34", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10776628", "map_id": "none", "name": "SUMO1:XPC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10785225", "map_id": "none", "name": "ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10785223", "map_id": "none", "name": "Unfolded G-protein beta subunit:CCT/TRiC:ATP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10771324", "map_id": "none", "name": "Binding of ERp57", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10771171", "map_id": "none", "name": "Homologues of PDIA3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "P32474", "map_id": "P32474", "name": "EUG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR518W", "map_id": "YDR518W", "name": "EUG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P17967", "map_id": "P17967", "name": "PDI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCL043C", "map_id": "YCL043C", "name": "PDI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10771320", "map_id": "none", "name": "unfolded protein:(Glc)1 (GlcNAc)2 (Man)9 (Asn)1:chaperone", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "P27825", "map_id": "P27825", "name": "CNE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL058W", "map_id": "YAL058W", "name": "CNE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:59080", "map_id": "CHEBI:59080", "name": "CHEBI:59080", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10771322", "map_id": "none", "name": "unfolded protein:(Glc)1 (GlcNAc)2 (Man)9 (Asn)1:chaperone:ERp57", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10781764", "map_id": "none", "name": "YOD1 binds VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10781760", "map_id": "P43558", "name": "OTU1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YFL044C", "map_id": "YFL044C", "name": "OTU1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10781762", "map_id": "none", "name": "YOD1:VCP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P43558", "map_id": "P43558", "name": "OTU1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771979", "map_id": "none", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_964828", "map_id": "CHEBI:60637", "name": "(GlcNAc)2 (Man)7bc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10787190", "map_id": "none", "name": "GPLD1 hydrolyses GPI-anchors from proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10787165", "map_id": "none", "name": "GPI-anchored proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P11491", "map_id": "P11491", "name": "PHO8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR481C", "map_id": "YDR481C", "name": "PHO8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q07825", "map_id": "Q07825", "name": "FRA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLL029W", "map_id": "YLL029W", "name": "FRA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_2197633", "map_id": "CHEBI:16749", "name": "PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10787182", "map_id": "none", "name": "proteins with cleaved GPI-anchors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10787187", "map_id": "P47014", "name": "GPLD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "YJL132W", "map_id": "YJL132W", "name": "GPLD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10777575", "map_id": "none", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10777567", "map_id": "P32324", "name": "EFT2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10777572", "map_id": "P32469", "name": "DPH5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YLR172C", "map_id": "YLR172C", "name": "DPH5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785227", "map_id": "none", "name": "ATP binds G-protein beta associated TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10776565", "map_id": "none", "name": "SUMOylation of RAD52 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776563", "map_id": "none", "name": "3SUMO1:RAD52", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10776732", "map_id": "none", "name": "SUMOylation of TOP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776722", "map_id": "P04786", "name": "TOP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YOL006C", "map_id": "YOL006C", "name": "TOP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776730", "map_id": "none", "name": "SUMO1:TOP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P04786", "map_id": "P04786", "name": "TOP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787048", "map_id": "none", "name": "N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787040", "map_id": "none", "name": "Homologues of Me3K79-EEF1A1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10787045", "map_id": "P53200", "name": "EFM5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YGR001C", "map_id": "YGR001C", "name": "EFM5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765485", "map_id": "none", "name": "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_75967", "map_id": "CHEBI:37554", "name": "FACoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8855666", "map_id": "CHEBI:52572", "name": "glucosaminyl-acyl-PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10765482", "map_id": "P47026", "name": "GWT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YJL091C", "map_id": "YJL091C", "name": "GWT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785867", "map_id": "none", "name": "UBA1 conjugates ubiquitin to UBA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10768446", "map_id": "none", "name": "Mitochondrial recruitment of Drp1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768442", "map_id": "P21576", "name": "VPS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YKR001C", "map_id": "YKR001C", "name": "VPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768444", "map_id": "P21576", "name": "VPS1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10768426", "map_id": "Q07451", "name": "YET3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YDL072C", "map_id": "YDL072C", "name": "YET3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768440", "map_id": "none", "name": "Nuclear translocation of catalytic domain of Mst3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10768434", "map_id": "P38692", "name": "KIC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YHR102W", "map_id": "YHR102W", "name": "KIC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768438", "map_id": "P38692", "name": "KIC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10768282", "map_id": "none", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10768278", "map_id": "none", "name": "HMGB1/HMGB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q03435", "map_id": "Q03435", "name": "NHP10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL002C", "map_id": "YDL002C", "name": "NHP10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02486", "map_id": "Q02486", "name": "ABF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR072W", "map_id": "YMR072W", "name": "ABF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P33417", "map_id": "P33417", "name": "IXR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL032C", "map_id": "YKL032C", "name": "IXR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03973", "map_id": "Q03973", "name": "HMO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR174W", "map_id": "YDR174W", "name": "HMO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768280", "map_id": "none", "name": "HMGB1/HMGB2- bound chromatin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10786382", "map_id": "none", "name": "OMA1 hydrolyses OPA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10786358", "map_id": "none", "name": "Homologues of OPA1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P54861", "map_id": "P54861", "name": "DNM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLL001W", "map_id": "YLL001W", "name": "DNM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P21576", "map_id": "P21576", "name": "VPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32266", "map_id": "P32266", "name": "MGM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR211C", "map_id": "YOR211C", "name": "MGM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10786366", "map_id": "none", "name": "Homologues of OPA1(195-960)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "species_10786374", "map_id": "none", "name": "Homologues of OPA1(88-194)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "species_10786379", "map_id": "P36163", "name": "OMA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YKR087C", "map_id": "YKR087C", "name": "OMA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761417", "map_id": "none", "name": "Pyruvate + CO2 + ATP => ADP + Orthophosphate + Oxaloacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_29376", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10761414", "map_id": "none", "name": "pyruvate carboxylase holoenzyme", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P11154", "map_id": "P11154", "name": "PYC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL062W", "map_id": "YGL062W", "name": "PYC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_199207", "map_id": "CHEBI:15956", "name": "Btn", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_113559", "map_id": "CHEBI:57288", "name": "Ac-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10761343", "map_id": "none", "name": "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29800", "map_id": "CHEBI:57604", "name": "1,3BPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29578", "map_id": "CHEBI:59776", "name": "GA3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761261", "map_id": "none", "name": "GAPDH tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P00360", "map_id": "P00360", "name": "TDH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL052W", "map_id": "YJL052W", "name": "TDH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00358", "map_id": "P00358", "name": "TDH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR009C", "map_id": "YJR009C", "name": "TDH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00359", "map_id": "P00359", "name": "TDH3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR192C", "map_id": "YGR192C", "name": "TDH3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768527", "map_id": "none", "name": "phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] => phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_372364", "map_id": "CHEBI:58702", "name": "PEP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_76190", "map_id": "CHEBI:30769", "name": "CIT", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29654", "map_id": "CHEBI:30769", "name": "CIT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29492", "map_id": "CHEBI:58702", "name": "PEP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10764027", "map_id": "P38152", "name": "CTP1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YBR291C", "map_id": "YBR291C", "name": "CTP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761339", "map_id": "none", "name": "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30014", "map_id": "CHEBI:32966", "name": "F1,6PP", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761336", "map_id": "none", "name": "FBP tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P09201", "map_id": "P09201", "name": "FBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR377C", "map_id": "YLR377C", "name": "FBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10762171", "map_id": "none", "name": "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10761676", "map_id": "none", "name": "MDH2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P17505", "map_id": "P17505", "name": "MDH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL085W", "map_id": "YKL085W", "name": "MDH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761407", "map_id": "none", "name": "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30485", "map_id": "CHEBI:58289", "name": "2PG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761404", "map_id": "none", "name": "enolase dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P42222", "map_id": "P42222", "name": "ERR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR323W", "map_id": "YMR323W", "name": "ERR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00924", "map_id": "P00924", "name": "ENO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR254W", "map_id": "YGR254W", "name": "ENO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00925", "map_id": "P00925", "name": "ENO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR174W", "map_id": "YHR174W", "name": "ENO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CX11", "map_id": "P0CX11", "name": "ERR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL281C", "map_id": "YPL281C", "name": "ERR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CX10", "map_id": "P0CX10", "name": "ERR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR393W", "map_id": "YOR393W", "name": "ERR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761341", "map_id": "none", "name": "D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_75970", "map_id": "CHEBI:57642", "name": "DHAP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761271", "map_id": "none", "name": "TPI1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P00942", "map_id": "P00942", "name": "TPI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR050C", "map_id": "YDR050C", "name": "TPI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768555", "map_id": "none", "name": "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10761359", "map_id": "none", "name": "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29728", "map_id": "CHEBI:58272", "name": "3PG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761356", "map_id": "none", "name": "PGK complexes", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P00560", "map_id": "P00560", "name": "PGK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCR012W", "map_id": "YCR012W", "name": "PGK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10788348", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024893", "map_id": "CHEBI:140192", "name": "17R(16)-epoxy-DHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024879", "map_id": "CHEBI:140202", "name": "AT-(N)PD1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10768259", "map_id": "none", "name": "LTA4H:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788372", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024873", "map_id": "CHEBI:140225", "name": "16S,17S-epoxy-DHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024886", "map_id": "CHEBI:138655", "name": "(N)PD1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10784338", "map_id": "none", "name": "Monoubiquitinated PTEN translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10784332", "map_id": "P53916", "name": "TEP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10784336", "map_id": "P53916", "name": "TEP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10784343", "map_id": "none", "name": "USP7 deubiquitinates monoubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10784340", "map_id": "P53916", "name": "TEP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10779695", "map_id": "P50101", "name": "UBP15", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10784345", "map_id": "none", "name": "Deubiquitinated PTEN translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10769655", "map_id": "none", "name": "K+-independent Li+/Ca2+ exchanger transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_425815", "map_id": "CHEBI:49713", "name": "Li+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_425810", "map_id": "CHEBI:49713", "name": "Li+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_74112", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10769652", "map_id": "P47144", "name": "ECM27", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YJR106W", "map_id": "YJR106W", "name": "ECM27", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787919", "map_id": "none", "name": "TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10763232", "map_id": "P13393", "name": "SPT15", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10787915", "map_id": "none", "name": "ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "CHEBI:142773", "map_id": "CHEBI:142773", "name": "CHEBI:142773", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_193132", "map_id": "CHEBI:16469", "name": "EST17b", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "P42944", "map_id": "P42944", "name": "GZF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL110C", "map_id": "YJL110C", "name": "GZF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P43574", "map_id": "P43574", "name": "GAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFL021W", "map_id": "YFL021W", "name": "GAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:27974", "map_id": "CHEBI:27974", "name": "CHEBI:27974", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_193066", "map_id": "CHEBI:17263", "name": "E1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "P18494", "map_id": "P18494", "name": "GLN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER040W", "map_id": "YER040W", "name": "GLN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787917", "map_id": "none", "name": "TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10787967", "map_id": "none", "name": "p-TEFb phosphorylates serine 2 in RNA polymerase II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10787962", "map_id": "none", "name": "MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "CHEBI:50114", "map_id": "CHEBI:50114", "name": "CHEBI:50114", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787964", "map_id": "none", "name": "MYB gene:hyperphosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10787903", "map_id": "none", "name": "FOXA1 and GATA3 bind to CCND1 promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10787891", "map_id": "none", "name": "Homologues of FOXA1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10787885", "map_id": "none", "name": "CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q03125", "map_id": "Q03125", "name": "NRG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR043C", "map_id": "YDR043C", "name": "NRG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787899", "map_id": "none", "name": "Homologues of GATA3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10787901", "map_id": "none", "name": "CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10787879", "map_id": "Q03125", "name": "NRG1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10787934", "map_id": "none", "name": "KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10787929", "map_id": "none", "name": "KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10787931", "map_id": "none", "name": "KDM4B-regulated genes:nucleosome:ESR1:ESTG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776763", "map_id": "P39956", "name": "RPH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10788368", "map_id": "none", "name": "Histone acetyltransferases are recruited to the TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10788364", "map_id": "none", "name": "ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P38074", "map_id": "P38074", "name": "HMT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR034C", "map_id": "YBR034C", "name": "HMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788356", "map_id": "none", "name": "histone acetyltransferases", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10788366", "map_id": "none", "name": "ESR1:estrogen:TFF1gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1:HATs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10788370", "map_id": "none", "name": "PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775032", "map_id": "P38074", "name": "HMT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10788362", "map_id": "none", "name": "ESR1:estrogen:TFF1 gene:DDX5:TBP:TFIIA:PRMT1:FOXA1:GATA3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10766225", "map_id": "none", "name": "glucokinase [nucleoplasm] => glucokinase [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10766223", "map_id": "none", "name": "Homologues of GCK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10761199", "map_id": "none", "name": "Homologues of GCK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10767350", "map_id": "none", "name": "AKT can phosphorylate RSK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10767323", "map_id": "P38070", "name": "YPK3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10767327", "map_id": "P38070", "name": "phospho-YPK3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10767347", "map_id": "none", "name": "p-T,p-S-AKT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10767701", "map_id": "none", "name": "PIP3 binds to RhoA and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10765227", "map_id": "P06780", "name": "RHO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10767699", "map_id": "none", "name": "PIP3:RhoA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788521", "map_id": "none", "name": "PIP3 recruits PDK1 and AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788519", "map_id": "none", "name": "PDK1:AKT:PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788567", "map_id": "none", "name": "PEX3:PEX19:class I PMP dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10788555", "map_id": "none", "name": "PEX3:PEX19:class I PMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "P28737", "map_id": "P28737", "name": "MSP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR028W", "map_id": "YGR028W", "name": "MSP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P28795", "map_id": "P28795", "name": "PEX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06563", "map_id": "Q06563", "name": "SYM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR251W", "map_id": "YLR251W", "name": "SYM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12462", "map_id": "Q12462", "name": "PEX11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL147C", "map_id": "YOL147C", "name": "PEX11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40515", "map_id": "P40515", "name": "FIS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL065C", "map_id": "YIL065C", "name": "FIS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788565", "map_id": "none", "name": "Class I Peroxisomal Membrane Proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10788569", "map_id": "none", "name": "PEX19:class I PMP binds PEX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10788553", "map_id": "none", "name": "PEX19:class I PMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788571", "map_id": "none", "name": "PEX19 binds class I peroxisomal membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788551", "map_id": "none", "name": "Class I Peroxisomal Membrane Proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10765200", "map_id": "none", "name": "Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10764341", "map_id": "none", "name": "Phosphorylation (Ser5) of RNA pol II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10764281", "map_id": "none", "name": "Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764229", "map_id": "none", "name": "TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q06339", "map_id": "Q06339", "name": "TFC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR362C", "map_id": "YDR362C", "name": "TFC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P46678", "map_id": "P46678", "name": "BDP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "BDP1", "map_id": "BDP1", "name": "BDP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P29056", "map_id": "P29056", "name": "BRF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "BRF1", "map_id": "BRF1", "name": "BRF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32367", "map_id": "P32367", "name": "TFC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "TFC1", "map_id": "TFC1", "name": "TFC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P33339", "map_id": "P33339", "name": "TFC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "TFC4", "map_id": "TFC4", "name": "TFC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32805", "map_id": "P32805", "name": "FZF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL254W", "map_id": "YGL254W", "name": "FZF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P34111", "map_id": "P34111", "name": "TFC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "TFC3", "map_id": "TFC3", "name": "TFC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764277", "map_id": "none", "name": "RNA Polymerase III Holoenzyme", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P32910", "map_id": "P32910", "name": "RPC34", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPC34", "map_id": "RPC34", "name": "RPC34", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P35718", "map_id": "P35718", "name": "RPC25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPC25", "map_id": "RPC25", "name": "RPC25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25441", "map_id": "P25441", "name": "RPC53", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPC53", "map_id": "RPC53", "name": "RPC53", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P17890", "map_id": "P17890", "name": "RPC31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPC31", "map_id": "RPC31", "name": "RPC31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22276", "map_id": "P22276", "name": "RET1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RET1", "map_id": "RET1", "name": "RET1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32349", "map_id": "P32349", "name": "RPC82", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPC82", "map_id": "RPC82", "name": "RPC82", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47076", "map_id": "P47076", "name": "RPC17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPC17", "map_id": "RPC17", "name": "RPC17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04307", "map_id": "Q04307", "name": "RPC11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPC11", "map_id": "RPC11", "name": "RPC11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P04051", "map_id": "P04051", "name": "RPO31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "RPO31", "map_id": "RPO31", "name": "RPO31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764279", "map_id": "none", "name": "RNA polymerase III:TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764473", "map_id": "none", "name": "Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764469", "map_id": "none", "name": "TFIIIB:TFIIIC:Type 2 Promoter Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764471", "map_id": "none", "name": "RNA Polymerase III:TFIIIB:TFIIIC:Type 2 Promoter Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764192", "map_id": "none", "name": "Binding of TFIIIA To type 1 Promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_76050", "map_id": "none", "name": "DNA with RNA Polymerase III Type 1 Closed Promoter", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10764188", "map_id": "P32805", "name": "FZF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10764190", "map_id": "none", "name": "TFIIIA:Type 1 Promoter complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10765180", "map_id": "none", "name": "Separation of elongating transcript from template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765176", "map_id": "none", "name": "Elongation complex prior to separation", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10765178", "map_id": "none", "name": "Elongation complex with separated and uncleaved transcript", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10765194", "map_id": "none", "name": "Pol II elongation complex moves on the template as transcript elongates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10765188", "map_id": "none", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764987", "map_id": "none", "name": "RNA Pol II (hypophosphorylated):capped pre-mRNA complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764989", "map_id": "none", "name": "RNA Pol II (hypophosphorylated) complex bound to DSIF protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10765166", "map_id": "none", "name": "Addition of nucleotides leads to transcript elongation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765162", "map_id": "none", "name": "Elongation complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10765033", "map_id": "none", "name": "Hypophosphorylation of RNA Pol II CTD by FCP1P protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764985", "map_id": "Q03254", "name": "FCP1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10788729", "map_id": "none", "name": "PRKCZ autophosphorylates downstream of estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10788721", "map_id": "none", "name": "PDPK1:PIP3:p-T410-PRKCZ", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10788726", "map_id": "none", "name": "PDPK1:PIP3:pS, p-T410 PRKCZ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788731", "map_id": "none", "name": "ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775860", "map_id": "none", "name": "p-T185,Y187 MAPK1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10767242", "map_id": "none", "name": "p-Y185,Y187 MAPK1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10788690", "map_id": "none", "name": "SPHK1 phosphorylates sphingosine in response to E2 stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1606609", "map_id": "CHEBI:16393", "name": "SPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_5218688", "map_id": "CHEBI:37550", "name": "S1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10786822", "map_id": "none", "name": "SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10786819", "map_id": "none", "name": "SLC25A18,A22", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q99297", "map_id": "Q99297", "name": "ODC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR222W", "map_id": "YOR222W", "name": "ODC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03028", "map_id": "Q03028", "name": "ODC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL134C", "map_id": "YPL134C", "name": "ODC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775307", "map_id": "none", "name": "Retromer recycles WLS to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10775301", "map_id": "none", "name": "WLS:retromer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "Q08826", "map_id": "Q08826", "name": "SNX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR357C", "map_id": "YOR357C", "name": "SNX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38759", "map_id": "P38759", "name": "VPS29", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR012W", "map_id": "YHR012W", "name": "VPS29", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40335", "map_id": "P40335", "name": "PEP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL053W", "map_id": "YJL053W", "name": "PEP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P34110", "map_id": "P34110", "name": "VPS35", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL154C", "map_id": "YJL154C", "name": "VPS35", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10775305", "map_id": "none", "name": "WLS:retromer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10768807", "map_id": "none", "name": "RAP1A exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768805", "map_id": "none", "name": "RAP1A:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10781313", "map_id": "none", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10781300", "map_id": "none", "name": "GCSH:DHLL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:50746", "map_id": "CHEBI:50746", "name": "CHEBI:50746", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39726", "map_id": "P39726", "name": "GCV3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL044C", "map_id": "YAL044C", "name": "GCV3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10781283", "map_id": "P39726", "name": "GCV3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10781310", "map_id": "none", "name": "DLD dimer:2xFAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P09624", "map_id": "P09624", "name": "LPD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFL018C", "map_id": "YFL018C", "name": "LPD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781298", "map_id": "none", "name": "PXLP-K754-GLDC dimer decarboxylates Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_159549", "map_id": "CHEBI:57305", "name": "Gly", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10781287", "map_id": "none", "name": "GCSH:SAMDLL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:14949", "map_id": "CHEBI:14949", "name": "CHEBI:14949", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10781295", "map_id": "none", "name": "PXLP-K754-GLDC dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P49095", "map_id": "P49095", "name": "GCV2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR189W", "map_id": "YMR189W", "name": "GCV2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781308", "map_id": "none", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_200671", "map_id": "CHEBI:15635", "name": "THF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5693984", "map_id": "CHEBI:12071", "name": "5,10-methylene-THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5693978", "map_id": "CHEBI:16134", "name": "NH3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10781305", "map_id": "P48015", "name": "GCV1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "YDR019C", "map_id": "YDR019C", "name": "GCV1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769352", "map_id": "none", "name": "G alpha (q) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10769349", "map_id": "none", "name": "G-protein alpha (q/11):GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10765298", "map_id": "none", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10765293", "map_id": "none", "name": "PLC-beta:G-alpha(q/11):PIP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10765295", "map_id": "none", "name": "PLC-beta:G-alpha(q/11):DAG:IP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10769199", "map_id": "none", "name": "Diacylgycerol activates Protein kinase C, alpha type", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10769197", "map_id": "none", "name": "Protein Kinase C, alpha type: DAG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10787442", "map_id": "none", "name": "FUNDC1 is phosphorylated by CK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787437", "map_id": "P18411", "name": "FUN14", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "YAL008W", "map_id": "YAL008W", "name": "phospho-FUN14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787440", "map_id": "P18411", "name": "phospho-FUN14", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10787455", "map_id": "none", "name": "FUNDC1 is phosphorylated by ULK1 at Ser17", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10787452", "map_id": "P18411", "name": "phospho-FUN14", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10787444", "map_id": "P53104", "name": "ATG1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "YGL180W", "map_id": "YGL180W", "name": "ATG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787722", "map_id": "none", "name": "LC3 binds the autophagosome membrane Atg5-Atg12 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_21994", "compartment_display": "phagocytic vesicle" }, { "id": "species_10787718", "map_id": "none", "name": "p-S17-FUNDC1:LC3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "P18411", "map_id": "P18411", "name": "phospho-FUN14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10777022", "map_id": "none", "name": "ATG5:ATG12", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "Q12380", "map_id": "Q12380", "name": "ATG5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL149W", "map_id": "YPL149W", "name": "ATG5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38316", "map_id": "P38316", "name": "ATG12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR217W", "map_id": "YBR217W", "name": "ATG12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787720", "map_id": "none", "name": "p-S17-FUNDC1:LC3:ATG5:ATG12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10787446", "map_id": "none", "name": "ULK1 Translocates to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10778616", "map_id": "P53104", "name": "ATG1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10787724", "map_id": "none", "name": "Phosphorylated FUNDC1 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10779041", "map_id": "P38182", "name": "ATG8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10788643", "map_id": "none", "name": "SGTA binds mislocalized membrane protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788608", "map_id": "none", "name": "Homologues of VAMP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10788577", "map_id": "none", "name": "SGTA dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q12118", "map_id": "Q12118", "name": "SGT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SGT2", "map_id": "SGT2", "name": "SGT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788641", "map_id": "none", "name": "Mislocalized membrane protein:SGTA dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788616", "map_id": "none", "name": "SGTA binds Tail-anchored protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788612", "map_id": "none", "name": "Tail-anchored proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P35179", "map_id": "P35179", "name": "SSS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR086C", "map_id": "YDR086C", "name": "SSS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P52871", "map_id": "P52871", "name": "SBH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER019C-A", "map_id": "YER019C-A", "name": "SBH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38374", "map_id": "P38374", "name": "YSY6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR162W-A", "map_id": "YBR162W-A", "name": "YSY6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40312", "map_id": "P40312", "name": "CYB5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL111C", "map_id": "YNL111C", "name": "CYB5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788614", "map_id": "none", "name": "Tail-anchored protein:SGTA dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773413", "map_id": "none", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429776", "map_id": "CHEBI:17636", "name": "SPHM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_429807", "map_id": "CHEBI:17761", "name": "CERA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1610735", "map_id": "CHEBI:18132", "name": "ChoP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10773410", "map_id": "none", "name": "Homologues of ENPP7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10773363", "map_id": "none", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10773360", "map_id": "none", "name": "SMPD2,3:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P40015", "map_id": "P40015", "name": "ISC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER019W", "map_id": "YER019W", "name": "ISC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785153", "map_id": "none", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_6810408", "map_id": "CHEBI:16500", "name": "PI5P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_6810412", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10785150", "map_id": "none", "name": "PIP4K2 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P38994", "map_id": "P38994", "name": "MSS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR208W", "map_id": "YDR208W", "name": "MSS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768746", "map_id": "none", "name": "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_380598", "map_id": "CHEBI:50157", "name": "HIALD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_380593", "map_id": "CHEBI:27823", "name": "HIAA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10762134", "map_id": "none", "name": "ALDH2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P40047", "map_id": "P40047", "name": "ALD5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER073W", "map_id": "YER073W", "name": "ALD5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766908", "map_id": "none", "name": "CYP51A1 demethylates LNSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194634", "map_id": "CHEBI:16521", "name": "LAN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_194644", "map_id": "CHEBI:17813", "name": "4,4DMCHtOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10766905", "map_id": "P10614", "name": "ERG11", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YHR007C", "map_id": "YHR007C", "name": "ERG11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10776925", "map_id": "none", "name": "HSP70:DNAJB1 binds HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775782", "map_id": "none", "name": "HSP70:DNAJB1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P36016", "map_id": "P36016", "name": "LHS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL073W", "map_id": "YKL073W", "name": "LHS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25294", "map_id": "P25294", "name": "SIS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL007C", "map_id": "YNL007C", "name": "SIS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22202", "map_id": "P22202", "name": "SSA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER103W", "map_id": "YER103W", "name": "SSA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P09435", "map_id": "P09435", "name": "SSA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL075C", "map_id": "YBL075C", "name": "SSA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P10591", "map_id": "P10591", "name": "SSA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL005C", "map_id": "YAL005C", "name": "SSA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10775812", "map_id": "none", "name": "HSF1 trimer:target gene", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P38889", "map_id": "P38889", "name": "phospho-SKN7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR206W", "map_id": "YHR206W", "name": "phospho-SKN7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P10961", "map_id": "P10961", "name": "phospho-HSF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL073W", "map_id": "YGL073W", "name": "phospho-HSF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10775814", "map_id": "none", "name": "HSP70:DNAJB1:HSF1 trimer:target gene", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10788335", "map_id": "none", "name": "RHOT2 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788331", "map_id": "none", "name": "RHOT2 effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32492", "map_id": "P32492", "name": "MYO4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL029C", "map_id": "YAL029C", "name": "MYO4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38297", "map_id": "P38297", "name": "FZO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR179C", "map_id": "YBR179C", "name": "FZO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P19524", "map_id": "P19524", "name": "MYO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR326W", "map_id": "YOR326W", "name": "MYO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788314", "map_id": "none", "name": "RHOT1:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "P39722", "map_id": "P39722", "name": "GEM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL048C", "map_id": "YAL048C", "name": "GEM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788333", "map_id": "none", "name": "RHOT2:GTP:RHOT2 effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10788319", "map_id": "none", "name": "RHOT1 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788316", "map_id": "none", "name": "RHOT1:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10788329", "map_id": "none", "name": "RHOT1 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10788325", "map_id": "none", "name": "Homologues of MYO19", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10788327", "map_id": "none", "name": "RHOT1:GTP:RHOT1 effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10788337", "map_id": "none", "name": "RHOT2 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10769669", "map_id": "none", "name": "SLC9A9 exchanges Na+ for H+ across the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "species_425999", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_173031", "compartment_display": "late endosome lumen", "complex": "false" }, { "id": "species_425977", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_173031", "compartment_display": "late endosome lumen", "complex": "false" }, { "id": "species_10769666", "map_id": "Q04121", "name": "NHX1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "YDR456W", "map_id": "YDR456W", "name": "NHX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769676", "map_id": "none", "name": "SLC9A6,7 exchange Na+ for H+ across the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_425978", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171043", "compartment_display": "early endosome lumen", "complex": "false" }, { "id": "species_425971", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171043", "compartment_display": "early endosome lumen", "complex": "false" }, { "id": "species_10769671", "map_id": "Q04121", "name": "NHX1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "reaction_10769681", "map_id": "none", "name": "Na+/H+ exchanger transport (at trans-golgi membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_425969", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_425958", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10769678", "map_id": "Q04121", "name": "NHX1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10766728", "map_id": "none", "name": "Squalene 2,3-epoxide cyclizes, forming lanosterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191309", "map_id": "CHEBI:15441", "name": "SQOX", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766725", "map_id": "P38604", "name": "ERG7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YHR072W", "map_id": "YHR072W", "name": "ERG7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787021", "map_id": "none", "name": "Formation of 4Fe-4S cluster on ISCA1:ISCA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10787001", "map_id": "none", "name": "GLRX5:2Fe-2S", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:33739", "map_id": "CHEBI:33739", "name": "CHEBI:33739", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02784", "map_id": "Q02784", "name": "GRX5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL059W", "map_id": "YPL059W", "name": "GRX5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787013", "map_id": "none", "name": "ISCA1:ISCA2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q12425", "map_id": "Q12425", "name": "ISA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR067W", "map_id": "YPR067W", "name": "ISA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q07821", "map_id": "Q07821", "name": "ISA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLL027W", "map_id": "YLL027W", "name": "ISA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10786999", "map_id": "Q02784", "name": "GRX5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10787015", "map_id": "none", "name": "ISCA1:ISCA2:4Fe-4S", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:49883", "map_id": "CHEBI:49883", "name": "CHEBI:49883", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787019", "map_id": "P53193", "name": "JAC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10789204", "map_id": "none", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10785545", "map_id": "none", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8870906", "map_id": "CHEBI:57930", "name": "NDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8870962", "map_id": "CHEBI:58043", "name": "NMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_109277", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10785539", "map_id": "none", "name": "NTPDase3:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P40009", "map_id": "P40009", "name": "YND1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER005W", "map_id": "YER005W", "name": "YND1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781870", "map_id": "none", "name": "HAGH hydrolyses (R)-S-LGSH to GSH and LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5694130", "map_id": "CHEBI:15694", "name": "(R)-S-LGSH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29708", "map_id": "CHEBI:422", "name": "LACT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10781867", "map_id": "none", "name": "HAGH-2:2xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q12320", "map_id": "Q12320", "name": "GLO4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR040W", "map_id": "YOR040W", "name": "GLO4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767283", "map_id": "none", "name": "CYB5A:heme reduces Asc.- to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767269", "map_id": "none", "name": "CYB5A:heme", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_1497805", "map_id": "CHEBI:59513", "name": "Asc.-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10767267", "map_id": "none", "name": "CYB5A:ferriheme", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "CHEBI:36144", "map_id": "CHEBI:36144", "name": "CHEBI:36144", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_198816", "map_id": "CHEBI:38290", "name": "AscH-", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10771989", "map_id": "none", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_964945", "map_id": "CHEBI:16410", "name": "PXA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_965146", "map_id": "CHEBI:18335", "name": "PXAP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10771986", "map_id": "none", "name": "2xPDXK:2xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10769063", "map_id": "none", "name": "acetyl-CoA + carnitine => acetylcarnitine + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_390294", "map_id": "CHEBI:17126", "name": "CAR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_353123", "map_id": "CHEBI:57288", "name": "Ac-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_390287", "map_id": "CHEBI:15960", "name": "ACAR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10769058", "map_id": "P32796", "name": "CAT2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10773576", "map_id": "none", "name": "PI4P is dephosphorylated to PI by SACM1L at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10773573", "map_id": "P32368", "name": "SAC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YKL212W", "map_id": "YKL212W", "name": "SAC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771313", "map_id": "none", "name": "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29970", "map_id": "CHEBI:16946", "name": "L-KYN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_893615", "map_id": "CHEBI:17442", "name": "AP-DOBu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8939576", "map_id": "none", "name": "I3LACT, I3PROPA", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:55528", "map_id": "CHEBI:55528", "name": "CHEBI:55528", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:43580", "map_id": "CHEBI:43580", "name": "CHEBI:43580", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10778606", "map_id": "none", "name": "XYLB phosphorylates D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5661281", "map_id": "CHEBI:17140", "name": "D-xylulose", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29790", "map_id": "CHEBI:57737", "name": "XY5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10778603", "map_id": "P42826", "name": "XKS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YGR194C", "map_id": "YGR194C", "name": "XKS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763390", "map_id": "none", "name": "GAR + 10-Formyl-THF => FGAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111338", "map_id": "CHEBI:143788", "name": "PRGA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_419151", "map_id": "CHEBI:57454", "name": "10-formyl-THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111354", "map_id": "CHEBI:147286", "name": "N-Formyl-GAR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111355", "map_id": "CHEBI:57453", "name": "THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10763376", "map_id": "P07244", "name": "ADE5,7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YGL234W", "map_id": "YGL234W", "name": "ADE5,7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784783", "map_id": "none", "name": "ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_6809801", "map_id": "CHEBI:85939", "name": "3Z-octenoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6809800", "map_id": "CHEBI:27537", "name": "2E-octenoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10784780", "map_id": "none", "name": "ECI2 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "P31787", "map_id": "P31787", "name": "ACB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR037C", "map_id": "YGR037C", "name": "ACB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10774954", "map_id": "none", "name": "ABCC1 transports cytosolic Cbl to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_3000241", "map_id": "CHEBI:28911", "name": "Cbl", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_3000125", "map_id": "CHEBI:28911", "name": "Cbl", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10781339", "map_id": "none", "name": "PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_379732", "map_id": "CHEBI:33384", "name": "L-Ser", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10781336", "map_id": "none", "name": "PXLP-K280-SHMT2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P37291", "map_id": "P37291", "name": "SHM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR058C", "map_id": "YLR058C", "name": "SHM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P37292", "map_id": "P37292", "name": "SHM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR263W", "map_id": "YBR263W", "name": "SHM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10762043", "map_id": "none", "name": "((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10761992", "map_id": "none", "name": "((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)GYG dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_70113", "map_id": "CHEBI:17925", "name": "Glc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10762040", "map_id": "none", "name": "poly((1,4)-alpha-glucosyl)GYG dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10761997", "map_id": "Q06625", "name": "GDB1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10769898", "map_id": "none", "name": "sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428203", "map_id": "CHEBI:37550", "name": "S1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428686", "map_id": "CHEBI:17553", "name": "PETA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428671", "map_id": "CHEBI:17585", "name": "HD2NAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10769895", "map_id": "Q05567", "name": "DPL1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YDR294C", "map_id": "YDR294C", "name": "DPL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787703", "map_id": "none", "name": "RBKS phosphorylates ribose to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8955853", "map_id": "CHEBI:47013", "name": "D-ribose", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_73578", "map_id": "CHEBI:78346", "name": "R5P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10787700", "map_id": "P25332", "name": "RBK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YCR036W", "map_id": "YCR036W", "name": "RBK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773027", "map_id": "none", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10773044", "map_id": "none", "name": "PA is hydrolysed to 1-acyl LPA by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1500604", "map_id": "CHEBI:16975", "name": "1-acyl LPA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772999", "map_id": "none", "name": "PLA2(1)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10766748", "map_id": "none", "name": "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191324", "map_id": "CHEBI:16057", "name": "DMAPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766745", "map_id": "none", "name": "IDI1 or 2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P15496", "map_id": "P15496", "name": "IDI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL117C", "map_id": "YPL117C", "name": "IDI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773106", "map_id": "none", "name": "MLCL is hydrolyzed to DLCL by PLA2G4A (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1498773", "map_id": "CHEBI:60430", "name": "MLCL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524085", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1498753", "map_id": "CHEBI:60431", "name": "DLCL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10773103", "map_id": "none", "name": "PLA2G4A:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10784748", "map_id": "none", "name": "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1806276", "map_id": "CHEBI:17283", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_426658", "map_id": "CHEBI:16749", "name": "PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10784742", "map_id": "none", "name": "MTMR6:MTMR9,MTMR8:MTMR9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P47147", "map_id": "P47147", "name": "YMR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR110W", "map_id": "YJR110W", "name": "YMR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761813", "map_id": "none", "name": "SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_31503", "map_id": "CHEBI:15786", "name": "HTMLYS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_31311", "map_id": "CHEBI:18020", "name": "TEABL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761810", "map_id": "none", "name": "SHMT1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10785576", "map_id": "none", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen" }, { "id": "species_8851509", "map_id": "none", "name": "CTP,GTP,UTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "true" }, { "id": "species_8851517", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "false" }, { "id": "species_8851518", "map_id": "none", "name": "CDP,GDP,UDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "true" }, { "id": "species_8851513", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "false" }, { "id": "species_5228597", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "false" }, { "id": "species_10785573", "map_id": "none", "name": "NTPDase7:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10767509", "map_id": "none", "name": "MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_200739", "map_id": "CHEBI:60473", "name": "5,10-methylene-THFPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_174404", "map_id": "CHEBI:63907", "name": "5-methyl-THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10767506", "map_id": "none", "name": "MTHFR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P53128", "map_id": "P53128", "name": "MET13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL125W", "map_id": "YGL125W", "name": "MET13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773109", "map_id": "none", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[9]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500646", "map_id": "CHEBI:18303", "name": "PS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1498724", "map_id": "CHEBI:52603", "name": "1-acyl LPS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10761833", "map_id": "none", "name": "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30401", "map_id": "CHEBI:16344", "name": "GAA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29916", "map_id": "CHEBI:16919", "name": "CRET", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761830", "map_id": "Q03305", "name": "RMT2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YDR465C", "map_id": "YDR465C", "name": "RMT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766996", "map_id": "none", "name": "2xENPP1 hydrolyzes FAD to FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29386", "map_id": "CHEBI:16238", "name": "FAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766993", "map_id": "none", "name": "2xENPP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10775588", "map_id": "none", "name": "GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775576", "map_id": "none", "name": "polyGlc-GYG2:GYS2-a tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P27472", "map_id": "P27472", "name": "phospho-GSY2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR258W", "map_id": "YLR258W", "name": "phospho-GSY2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P23337", "map_id": "P23337", "name": "phospho-GSY1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFR015C", "map_id": "YFR015C", "name": "phospho-GSY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10775586", "map_id": "none", "name": "glycogen-GYG2:GYS2-a tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10775557", "map_id": "P32775", "name": "GLC3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YEL011W", "map_id": "YEL011W", "name": "GLC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766523", "map_id": "none", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189464", "map_id": "CHEBI:58126", "name": "PBG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_189449", "map_id": "CHEBI:57845", "name": "HMBL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766520", "map_id": "none", "name": "HMBS:DIPY", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:36319", "map_id": "CHEBI:36319", "name": "CHEBI:36319", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P28789", "map_id": "P28789", "name": "HEM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL205C", "map_id": "YDL205C", "name": "HEM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775584", "map_id": "none", "name": "Autoglucosylation of GYG2 complexed with GYS2-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775581", "map_id": "none", "name": "GYG2:GYS2-a tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10775574", "map_id": "none", "name": "oligoGlc-GYG2:GYS2-a tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10767006", "map_id": "none", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196931", "map_id": "CHEBI:17015", "name": "RIB", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10767003", "map_id": "none", "name": "RFK:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q03778", "map_id": "Q03778", "name": "FMN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR236C", "map_id": "YDR236C", "name": "FMN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773229", "map_id": "none", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_426955", "map_id": "CHEBI:17962", "name": "CDP-DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10773226", "map_id": "none", "name": "CDIPT:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P06197", "map_id": "P06197", "name": "PIS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR113W", "map_id": "YPR113W", "name": "PIS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787576", "map_id": "none", "name": "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_2173763", "map_id": "CHEBI:60479", "name": "lysoPC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8952253", "map_id": "CHEBI:16870", "name": "GPCho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8954142", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10787573", "map_id": "P54857", "name": "TGL2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10761616", "map_id": "none", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_508190", "map_id": "none", "name": "Leu, Ile, Val", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:58045", "map_id": "CHEBI:58045", "name": "CHEBI:58045", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_351964", "map_id": "CHEBI:57427", "name": "L-Leu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "CHEBI:57762", "map_id": "CHEBI:57762", "name": "CHEBI:57762", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_508181", "map_id": "none", "name": "KIC, KMVA, KIV", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:28654", "map_id": "CHEBI:28654", "name": "CHEBI:28654", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16530", "map_id": "CHEBI:16530", "name": "CHEBI:16530", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17865", "map_id": "CHEBI:17865", "name": "CHEBI:17865", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10761613", "map_id": "none", "name": "BCAT2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P47176", "map_id": "P47176", "name": "BAT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR148W", "map_id": "YJR148W", "name": "BAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38891", "map_id": "P38891", "name": "BAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR208W", "map_id": "YHR208W", "name": "BAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10778320", "map_id": "none", "name": "SORD oxidizes D-sorbitol to Fru", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5652213", "map_id": "CHEBI:17924", "name": "D-sorbitol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29532", "map_id": "CHEBI:15824", "name": "Fru", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10778317", "map_id": "none", "name": "SORD tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q07993", "map_id": "Q07993", "name": "XYL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR070C", "map_id": "YLR070C", "name": "XYL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q07786", "map_id": "Q07786", "name": "SOR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL246C", "map_id": "YDL246C", "name": "SOR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P35497", "map_id": "P35497", "name": "SOR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR159W", "map_id": "YJR159W", "name": "SOR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763347", "map_id": "none", "name": "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29602", "map_id": "CHEBI:58053", "name": "IMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111584", "map_id": "CHEBI:57464", "name": "XMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10763345", "map_id": "none", "name": "IMPDH tetramers:IMPDH inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "LigandDisplayForward?ligandId=6832", "map_id": "LigandDisplayForward?ligandId=6832", "name": "LigandDisplayForward?ligandId=6832", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=6845", "map_id": "LigandDisplayForward?ligandId=6845", "name": "LigandDisplayForward?ligandId=6845", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=6842", "map_id": "LigandDisplayForward?ligandId=6842", "name": "LigandDisplayForward?ligandId=6842", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10788488", "map_id": "none", "name": "PXLP-K56-SRR dimer deaminates L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788216", "map_id": "none", "name": "PXLP-K56-SRR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P36007", "map_id": "P36007", "name": "SRY1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL218C", "map_id": "YKL218C", "name": "SRY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784328", "map_id": "none", "name": "SC5D desaturates LTHSOL to 7-dehydroCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6807054", "map_id": "CHEBI:17168", "name": "LTHSOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_6807057", "map_id": "CHEBI:17759", "name": "7-dehydroCHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10773042", "map_id": "none", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498729", "map_id": "CHEBI:28936", "name": "2-acyl LPE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10773037", "map_id": "Q08548", "name": "ALE1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10764110", "map_id": "none", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10764107", "map_id": "none", "name": "AGPAT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q08750", "map_id": "Q08750", "name": "MUM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR298W", "map_id": "YOR298W", "name": "MUM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38226", "map_id": "P38226", "name": "CST26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR042C", "map_id": "YBR042C", "name": "CST26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769889", "map_id": "none", "name": "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428275", "map_id": "CHEBI:16893", "name": "SPAP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428694", "map_id": "CHEBI:16566", "name": "SPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10769886", "map_id": "none", "name": "SGPP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P47013", "map_id": "P47013", "name": "LCB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL134W", "map_id": "YJL134W", "name": "LCB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P23501", "map_id": "P23501", "name": "YSR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR053C", "map_id": "YKR053C", "name": "YSR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766913", "map_id": "none", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194633", "map_id": "CHEBI:18364", "name": "14DMLANOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10766910", "map_id": "P32462", "name": "ERG24", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10773596", "map_id": "none", "name": "PI4KB binds to ARF1/3:GTP at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10773594", "map_id": "P39104", "name": "PIK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YNL267W", "map_id": "YNL267W", "name": "PIK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10773521", "map_id": "none", "name": "ARF1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10773523", "map_id": "none", "name": "ARF1/3:GTP:PI4KB", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "P39104", "map_id": "P39104", "name": "PIK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761653", "map_id": "none", "name": "isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_29938", "map_id": "CHEBI:151", "name": "ISCIT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10761650", "map_id": "none", "name": "IDH3 complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P28241", "map_id": "P28241", "name": "IDH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR136W", "map_id": "YOR136W", "name": "IDH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P28834", "map_id": "P28834", "name": "IDH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "IDH1", "map_id": "IDH1", "name": "IDH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10774302", "map_id": "none", "name": "SeMet is converted to AdoSeMet by MAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5357707", "map_id": "CHEBI:30021", "name": "SeMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5357652", "map_id": "CHEBI:9066", "name": "AdoSeMet", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10771159", "map_id": "none", "name": "ACSL3,4 ligate CoA to AA to form AA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29768", "map_id": "CHEBI:15843", "name": "AA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_548819", "map_id": "CHEBI:15514", "name": "AA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10771156", "map_id": "none", "name": "ACSL3,4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P47912", "map_id": "P47912", "name": "FAA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR246W", "map_id": "YMR246W", "name": "FAA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39002", "map_id": "P39002", "name": "FAA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL009W", "map_id": "YIL009W", "name": "FAA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P30624", "map_id": "P30624", "name": "FAA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR317W", "map_id": "YOR317W", "name": "FAA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10783830", "map_id": "none", "name": "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6800352", "map_id": "CHEBI:17389", "name": "2AG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76103", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10783823", "map_id": "Q08650", "name": "DGA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YOR245C", "map_id": "YOR245C", "name": "DGA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773032", "map_id": "none", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10772937", "map_id": "none", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498740", "map_id": "CHEBI:62747", "name": "1-acyl LPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1483256", "map_id": "CHEBI:17517", "name": "PG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10772934", "map_id": "none", "name": "Homologues of LPGAT1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q12185", "map_id": "Q12185", "name": "LPGAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR018C", "map_id": "YDR018C", "name": "LPGAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764651", "map_id": "none", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6788782", "map_id": "none", "name": "(d)NDPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:57667", "map_id": "CHEBI:57667", "name": "CHEBI:57667", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:58593", "map_id": "CHEBI:58593", "name": "CHEBI:58593", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_6788778", "map_id": "none", "name": "(d)NMPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_109378", "map_id": "CHEBI:57566", "name": "dCMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_109386", "map_id": "CHEBI:58245", "name": "2'-deoxyadenosine 5'-monophosphate", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10764648", "map_id": "none", "name": "AK5,7,8,9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P26364", "map_id": "P26364", "name": "ADK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER170W", "map_id": "YER170W", "name": "ADK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P07170", "map_id": "P07170", "name": "ADK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR226W", "map_id": "YDR226W", "name": "ADK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763371", "map_id": "none", "name": "SAICAR => AICAR + Fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111399", "map_id": "CHEBI:58443", "name": "SAICAR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29586", "map_id": "CHEBI:29806", "name": "FUMA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111409", "map_id": "CHEBI:58475", "name": "AICAR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10763368", "map_id": "none", "name": "ADSL tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q05911", "map_id": "Q05911", "name": "ADE13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR359W", "map_id": "YLR359W", "name": "ADE13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773168", "map_id": "none", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10766900", "map_id": "none", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_194681", "map_id": "CHEBI:17813", "name": "4,4DMCHtOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_194688", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_194725", "map_id": "CHEBI:16474", "name": "NADPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_194704", "map_id": "CHEBI:18364", "name": "14DMLANOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_194668", "map_id": "CHEBI:18009", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10766897", "map_id": "P32462", "name": "ERG24", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "reaction_10772957", "map_id": "none", "name": "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1524023", "map_id": "CHEBI:16929", "name": "GPETA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10775612", "map_id": "none", "name": "Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775533", "map_id": "none", "name": "oligoGlc-GYG1:GYS1-b tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10775609", "map_id": "none", "name": "polyGlc-GYG1:GYS1-b tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10775536", "map_id": "none", "name": "Autoglucosylation of GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775531", "map_id": "none", "name": "GYG1:GYS1-b tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10761781", "map_id": "none", "name": "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_34351", "map_id": "CHEBI:17380", "name": "3HKYN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761778", "map_id": "P38169", "name": "BNA4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YBL098W", "map_id": "YBL098W", "name": "BNA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767519", "map_id": "none", "name": "FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_200665", "map_id": "CHEBI:15641", "name": "5-methyl-THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10767056", "map_id": "Q08645", "name": "MET7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YOR241W", "map_id": "YOR241W", "name": "MET7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761689", "map_id": "none", "name": "Fumarate + H2O <=> (S)-Malate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113588", "map_id": "CHEBI:18012", "name": "FUMA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10761686", "map_id": "none", "name": "FH tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P08417", "map_id": "P08417", "name": "FUM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL262W", "map_id": "YPL262W", "name": "FUM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784728", "map_id": "none", "name": "MTMR8 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10784722", "map_id": "P47147", "name": "YMR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10784724", "map_id": "P47147", "name": "YMR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10784726", "map_id": "none", "name": "MTMR8:MTMR9", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10769851", "map_id": "none", "name": "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428163", "map_id": "CHEBI:16566", "name": "SPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10769848", "map_id": "none", "name": "SPHK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q12246", "map_id": "Q12246", "name": "LCB4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR171C", "map_id": "YOR171C", "name": "LCB4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47045", "map_id": "P47045", "name": "TIM54", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "TIM54", "map_id": "TIM54", "name": "TIM54", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773157", "map_id": "none", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498738", "map_id": "CHEBI:29017", "name": "1-acyl LPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10767738", "map_id": "none", "name": "depalmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10767589", "map_id": "none", "name": "palmitoylated, myristoylated eNOS dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_76168", "map_id": "CHEBI:15756", "name": "PALM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17941", "compartment_display": "early endosome", "complex": "false" }, { "id": "species_10767646", "map_id": "none", "name": "myristoylated eNOS dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10767735", "map_id": "none", "name": "LYPLA1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q12354", "map_id": "Q12354", "name": "LYPLA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR118C", "map_id": "YLR118C", "name": "LYPLA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763944", "map_id": "none", "name": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500006", "map_id": "none", "name": "(d)CDP, UDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500009", "map_id": "none", "name": "(d)CMP, UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10763053", "map_id": "P15700", "name": "URA6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YKL024C", "map_id": "YKL024C", "name": "URA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761637", "map_id": "none", "name": "saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_30176", "map_id": "CHEBI:16927", "name": "SACN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113556", "map_id": "CHEBI:17917", "name": "2AMAS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10761631", "map_id": "none", "name": "AASS tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P38999", "map_id": "P38999", "name": "LYS9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNR050C", "map_id": "YNR050C", "name": "LYS9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761851", "map_id": "none", "name": "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29996", "map_id": "CHEBI:16863", "name": "PDG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29732", "map_id": "CHEBI:17363", "name": "RU5P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761848", "map_id": "none", "name": "PGD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38720", "map_id": "P38720", "name": "GND1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR183W", "map_id": "YHR183W", "name": "GND1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773119", "map_id": "none", "name": "CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524079", "map_id": "CHEBI:17504", "name": "1-acyl LPC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524072", "map_id": "CHEBI:28494", "name": "cardiolipin", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524075", "map_id": "CHEBI:16110", "name": "PC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10773113", "map_id": "Q06510", "name": "TAZ1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10784773", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6809774", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_422529", "map_id": "CHEBI:16500", "name": "PI5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10784765", "map_id": "none", "name": "MTMR2:SBF1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10761717", "map_id": "none", "name": "Succinate <=> Fumarate (with FAD redox reaction on enzyme)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113536", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10761714", "map_id": "none", "name": "SDH complex (ox.)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P21801", "map_id": "P21801", "name": "SDH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLL041C", "map_id": "YLL041C", "name": "SDH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q00711", "map_id": "Q00711", "name": "SDH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL148C", "map_id": "YKL148C", "name": "SDH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08749", "map_id": "Q08749", "name": "TIM18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "TIM18", "map_id": "TIM18", "name": "TIM18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P33421", "map_id": "P33421", "name": "SDH3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL141W", "map_id": "YKL141W", "name": "SDH3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764120", "map_id": "none", "name": "Conversion of Glycerol to Glycerol-3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_76114", "map_id": "CHEBI:15978", "name": "G3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10764115", "map_id": "P32190", "name": "GUT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YHL032C", "map_id": "YHL032C", "name": "GUT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763395", "map_id": "none", "name": "adenylosuccinate => adenosine 5'-monophosphate + fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_35141", "map_id": "CHEBI:57567", "name": "ADS", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10767535", "map_id": "none", "name": "SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_197969", "map_id": "CHEBI:28624", "name": "THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773035", "map_id": "none", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498730", "map_id": "CHEBI:27923", "name": "2-acyl LPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10767447", "map_id": "none", "name": "pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767435", "map_id": "none", "name": "Btn-ACACB:2Mn2+ polymer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "Q00955", "map_id": "Q00955", "name": "phospho-ACC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNR016C", "map_id": "YNR016C", "name": "phospho-ACC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10767442", "map_id": "none", "name": "Btn-p-S79-ACACB:2Mn2+ polymer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10767444", "map_id": "none", "name": "AMPK heterotrimer (active)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P34164", "map_id": "P34164", "name": "SIP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL208W", "map_id": "YGL208W", "name": "SIP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04739", "map_id": "Q04739", "name": "GAL83", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER027C", "map_id": "YER027C", "name": "GAL83", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32578", "map_id": "P32578", "name": "SIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR422C", "map_id": "YDR422C", "name": "SIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P12904", "map_id": "P12904", "name": "SNF4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL115W", "map_id": "YGL115W", "name": "SNF4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38845", "map_id": "P38845", "name": "CRP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR146W", "map_id": "YHR146W", "name": "CRP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53885", "map_id": "P53885", "name": "MDG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL173C", "map_id": "YNL173C", "name": "MDG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761230", "map_id": "none", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10761125", "map_id": "none", "name": "PGM:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773584", "map_id": "none", "name": "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_1806200", "map_id": "CHEBI:17283", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "species_1806199", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "species_10773463", "map_id": "P47147", "name": "YMR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773458", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_392417", "map_id": "CHEBI:17526", "name": "PI4P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10773453", "map_id": "P42951", "name": "LSB6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YJL100W", "map_id": "YJL100W", "name": "LSB6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786908", "map_id": "none", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6786250", "map_id": "CHEBI:15727", "name": "CARN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8876775", "map_id": "CHEBI:18323", "name": "Anserine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10786905", "map_id": "P53934", "name": "CARNMT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YNL092W", "map_id": "YNL092W", "name": "CARNMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767466", "map_id": "none", "name": "NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_8938083", "map_id": "CHEBI:15763", "name": "NAMN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_8938090", "map_id": "CHEBI:18304", "name": "NAAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10767463", "map_id": "none", "name": "4xNMNAT3:4xMg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q06178", "map_id": "Q06178", "name": "NMA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR328W", "map_id": "YLR328W", "name": "NMA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53204", "map_id": "P53204", "name": "NMA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR010W", "map_id": "YGR010W", "name": "NMA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10762169", "map_id": "none", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762166", "map_id": "none", "name": "Homologues of ACSS2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P52910", "map_id": "P52910", "name": "ACS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR153C", "map_id": "YLR153C", "name": "ACS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q01574", "map_id": "Q01574", "name": "ACS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL054C", "map_id": "YAL054C", "name": "ACS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784745", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1806224", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1806240", "map_id": "CHEBI:16500", "name": "PI5P", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10776275", "map_id": "none", "name": "PPP1R3C binds to glycogen:GYG1:GYS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775552", "map_id": "none", "name": "glycogen-GYG1:GYS1-a tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10776211", "map_id": "none", "name": "Homologues of PPP1R3C", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P40187", "map_id": "P40187", "name": "PIG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL045W", "map_id": "YIL045W", "name": "PIG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40036", "map_id": "P40036", "name": "GIP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER054C", "map_id": "YER054C", "name": "GIP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06216", "map_id": "Q06216", "name": "PIG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR273C", "map_id": "YLR273C", "name": "PIG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P28006", "map_id": "P28006", "name": "GAC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR178C", "map_id": "YOR178C", "name": "GAC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776273", "map_id": "none", "name": "PPP1R3C:glycogen-GYG1:GYS1-a tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773161", "map_id": "none", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10767321", "map_id": "none", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10761868", "map_id": "none", "name": "RPE:Fe2+ dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P46969", "map_id": "P46969", "name": "RPE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL121C", "map_id": "YJL121C", "name": "RPE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10776271", "map_id": "none", "name": "EPM2A dimer dephosphorylates phosphoglycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10776268", "map_id": "none", "name": "EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10776261", "map_id": "none", "name": "EPM2A:PPP1R3C:glycogen-GYG1:GYS1-a tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10770915", "map_id": "none", "name": "PGYM b dimer:AMP complex <=> PGYM dimer, b form + 2 AMP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770913", "map_id": "none", "name": "PGYM b dimer:AMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10761929", "map_id": "none", "name": "PGYM dimer, b form", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10781323", "map_id": "none", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5694074", "map_id": "CHEBI:17158", "name": "MGXL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10781320", "map_id": "none", "name": "GLO1 dimer:2xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P50107", "map_id": "P50107", "name": "GLO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML004C", "map_id": "YML004C", "name": "GLO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773592", "map_id": "none", "name": "PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10769915", "map_id": "none", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_419305", "map_id": "CHEBI:37550", "name": "S1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_428662", "map_id": "CHEBI:16393", "name": "SPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10769912", "map_id": "none", "name": "Homologues of PPAP2A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10774502", "map_id": "none", "name": "ITPA hydrolyses ITP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2509836", "map_id": "CHEBI:61402", "name": "ITP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10774499", "map_id": "none", "name": "ITPA dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P47119", "map_id": "P47119", "name": "HAM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR069C", "map_id": "YJR069C", "name": "HAM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773490", "map_id": "none", "name": "PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1806165", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10773487", "map_id": "Q08227", "name": "INP54", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773049", "map_id": "none", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10781088", "map_id": "none", "name": "ALD3A1 oxidises 4HPCP to CXPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5692409", "map_id": "CHEBI:196991", "name": "4HPCP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5692433", "map_id": "CHEBI:3410", "name": "CXPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10781085", "map_id": "Q04458", "name": "HFD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10774505", "map_id": "none", "name": "ITPA hydrolyses XTP to XMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2509848", "map_id": "CHEBI:61314", "name": "XTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10766958", "map_id": "none", "name": "2xTPK1:Mg2+ phosphorylates THMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196934", "map_id": "CHEBI:18385", "name": "THMN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29480", "map_id": "CHEBI:58937", "name": "ThDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10766955", "map_id": "none", "name": "2xTPK1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P35202", "map_id": "P35202", "name": "THI80", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR143C", "map_id": "YOR143C", "name": "THI80", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784761", "map_id": "none", "name": "PI3P is dephosphorylated to PI by MTM1:MTMR12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_10784752", "map_id": "none", "name": "MTM1:MTMR12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10764851", "map_id": "none", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764848", "map_id": "none", "name": "ADSS, ADSSL1 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P80210", "map_id": "P80210", "name": "ADE12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL220W", "map_id": "YNL220W", "name": "ADE12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786559", "map_id": "none", "name": "NMRK2 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8869377", "map_id": "CHEBI:15927", "name": "NR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8869353", "map_id": "CHEBI:14649", "name": "NMN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10786553", "map_id": "P53915", "name": "NRK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YNL129W", "map_id": "YNL129W", "name": "NRK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761438", "map_id": "none", "name": "glutamate + acetyl CoA => N-acetyl glutamate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_30471", "map_id": "CHEBI:17533", "name": "NAcGlu", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10761435", "map_id": "Q01217", "name": "ARG5,6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "YER069W", "map_id": "YER069W", "name": "ARG5,6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_374064", "map_id": "CHEBI:32682", "name": "L-Arg", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10773539", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_1806180", "map_id": "CHEBI:17526", "name": "PI4P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "reaction_10773138", "map_id": "none", "name": "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524042", "map_id": "CHEBI:17517", "name": "PG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524047", "map_id": "CHEBI:27923", "name": "2-acyl LPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10773088", "map_id": "none", "name": "PLA2G", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10770921", "map_id": "none", "name": "poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762038", "map_id": "none", "name": "poly((1,4)-alpha-glucosyl)GYG2 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10770919", "map_id": "none", "name": "GYG2 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10762009", "map_id": "none", "name": "PGYL dimer a form", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10761311", "map_id": "none", "name": "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10761308", "map_id": "none", "name": "PFK tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_30533", "map_id": "CHEBI:28602", "name": "D-Fructose 2,6-bisphosphate", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10766705", "map_id": "none", "name": "FDPS dimer transfers IPPP to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191409", "map_id": "CHEBI:17211", "name": "GPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766699", "map_id": "none", "name": "holo-FDPS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P08524", "map_id": "P08524", "name": "ERG20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL167W", "map_id": "YJL167W", "name": "ERG20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772005", "map_id": "none", "name": "2xPNPO:2xFMN oxidizes PXAP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29390", "map_id": "CHEBI:18405", "name": "PXLP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772000", "map_id": "none", "name": "2xPNPO:2xFMN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38075", "map_id": "P38075", "name": "PDX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR035C", "map_id": "YBR035C", "name": "PDX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764030", "map_id": "none", "name": "Transport of Citrate from Mitochondrial Matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10771299", "map_id": "none", "name": "IDO2 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29500", "map_id": "CHEBI:57912", "name": "L-Trp", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_33179", "map_id": "CHEBI:18377", "name": "NFK", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10771296", "map_id": "none", "name": "IDO2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P47125", "map_id": "P47125", "name": "BNA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR078W", "map_id": "YJR078W", "name": "BNA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768921", "map_id": "none", "name": "ALDH3A2-2 oxidizes pristanal to pristanate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389636", "map_id": "CHEBI:49189", "name": "Pristanal", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6811612", "map_id": "CHEBI:77268", "name": "pristanate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10768918", "map_id": "none", "name": "ALDH3A2-2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10767051", "map_id": "none", "name": "NADSYN1 hexamer amidates NAAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_197256", "map_id": "CHEBI:18304", "name": "NAAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10767048", "map_id": "none", "name": "NADSYN1 hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38795", "map_id": "P38795", "name": "QNS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR074W", "map_id": "YHR074W", "name": "QNS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767059", "map_id": "none", "name": "FPGS-2 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10763076", "map_id": "none", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111647", "map_id": "CHEBI:58228", "name": "CAP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10763067", "map_id": "none", "name": "CAD hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P07259", "map_id": "P07259", "name": "URA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL130C", "map_id": "YJL130C", "name": "URA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P03965", "map_id": "P03965", "name": "CPA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR109C", "map_id": "YJR109C", "name": "CPA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766605", "map_id": "none", "name": "UROD decarboxylates URO1 to COPRO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_190157", "map_id": "CHEBI:28766", "name": "URO1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_190128", "map_id": "CHEBI:28607", "name": "COPRO1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766550", "map_id": "none", "name": "2xUROD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32347", "map_id": "P32347", "name": "HEM12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR047W", "map_id": "YDR047W", "name": "HEM12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766872", "map_id": "none", "name": "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196366", "map_id": "CHEBI:63843", "name": "pregn-5-ene-3,20-dione-17-ol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193092", "map_id": "CHEBI:17252", "name": "17aHPROG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766844", "map_id": "none", "name": "HSD2B1 dimer, HSD3B2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P53199", "map_id": "P53199", "name": "ERG26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773558", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "species_1806289", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "species_1806212", "map_id": "CHEBI:16500", "name": "PI5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "reaction_10773091", "map_id": "none", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524027", "map_id": "CHEBI:62747", "name": "1-acyl LPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10784326", "map_id": "none", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6807477", "map_id": "CHEBI:64084", "name": "S-NADPHX", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10784323", "map_id": "P36059", "name": "NNR2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "YKL151C", "map_id": "YKL151C", "name": "NNR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761600", "map_id": "none", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_508182", "map_id": "none", "name": "Leu, Ile, Val", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_508187", "map_id": "none", "name": "KIC,KMVA,KIV", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10761597", "map_id": "none", "name": "BCAT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773166", "map_id": "none", "name": "PS is hydrolyzed to 2-acyl LPS by PLA2[10]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498722", "map_id": "CHEBI:37646", "name": "2-acyl LPS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10763142", "map_id": "none", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_109382", "map_id": "CHEBI:246422", "name": "dUMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_109366", "map_id": "CHEBI:63528", "name": "TMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_73604", "map_id": "CHEBI:57451", "name": "DHF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10763139", "map_id": "none", "name": "TS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P06785", "map_id": "P06785", "name": "CDC21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR074C", "map_id": "YOR074C", "name": "CDC21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767724", "map_id": "none", "name": "palmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10767644", "map_id": "P16603", "name": "NCP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_200993", "map_id": "CHEBI:15525", "name": "PALM-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10767716", "map_id": "P16603", "name": "NCP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10767721", "map_id": "Q06551", "name": "ERF2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "YLR246W", "map_id": "YLR246W", "name": "ERF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767524", "map_id": "none", "name": "Mitochondrial FPGS-1 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_200679", "map_id": "CHEBI:28624", "name": "THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10767521", "map_id": "Q08645", "name": "MET7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10763403", "map_id": "none", "name": "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_73871", "map_id": "CHEBI:57286", "name": "ACA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_73917", "map_id": "CHEBI:15467", "name": "HMG CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10763400", "map_id": "P54839", "name": "ERG13", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "YML126C", "map_id": "YML126C", "name": "ERG13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785542", "map_id": "none", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8870907", "map_id": "CHEBI:61557", "name": "NTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10773526", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1524146", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10770990", "map_id": "none", "name": "(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_482627", "map_id": "none", "name": "(d)NDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:60471", "map_id": "CHEBI:60471", "name": "CHEBI:60471", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:58369", "map_id": "CHEBI:58369", "name": "CHEBI:58369", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:58595", "map_id": "CHEBI:58595", "name": "CHEBI:58595", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_482625", "map_id": "none", "name": "(d)NTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500739", "map_id": "CHEBI:61555", "name": "dUTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_110644", "map_id": "CHEBI:61404", "name": "dATP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10769859", "map_id": "none", "name": "phytoceramide + H2O => stearate + phytosphingosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9025544", "map_id": "CHEBI:31998", "name": "N-acylphytosphingosine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_3632878", "map_id": "CHEBI:9254", "name": "STEA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428237", "map_id": "CHEBI:46961", "name": "phytosphingosine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10769856", "map_id": "Q02896", "name": "YDC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YPL087W", "map_id": "YPL087W", "name": "YDC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10776266", "map_id": "none", "name": "EPM2A dimer dephosphorylates phosphoglycogen-GYG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10776263", "map_id": "none", "name": "EPM2A:PPP1R3C:phosphoglycogen-GYG2:GYS2-a tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10776227", "map_id": "none", "name": "EPM2A:PPP1R3C:glycogen-GYG2:GYS2-a tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10767041", "map_id": "none", "name": "QPRT transfers PRIB to QUIN to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_73566", "map_id": "CHEBI:58017", "name": "PRPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_197238", "map_id": "CHEBI:29959", "name": "QUIN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_197220", "map_id": "CHEBI:15763", "name": "NAMN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10767038", "map_id": "P43619", "name": "BNA6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YFR047C", "map_id": "YFR047C", "name": "BNA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785578", "map_id": "none", "name": "NTPDase8 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9726184", "map_id": "none", "name": "ATP,GTP,ITP,CTP,TTP,UTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_9726189", "map_id": "none", "name": "ADP,GDP,IDP,CDP,TDP,UDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:58280", "map_id": "CHEBI:58280", "name": "CHEBI:58280", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785532", "map_id": "none", "name": "NTPDase2:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10774297", "map_id": "none", "name": "FDXR transfers electrons to FDX1,2 (FDX1L)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10774293", "map_id": "none", "name": "FDXR:FADH2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P48360", "map_id": "P48360", "name": "ARH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR376W", "map_id": "YDR376W", "name": "ARH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_31649", "map_id": "CHEBI:17877", "name": "FADH2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10772859", "map_id": "none", "name": "FDX1,FDX2 (oxidized)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:33737", "map_id": "CHEBI:33737", "name": "CHEBI:33737", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12184", "map_id": "Q12184", "name": "YAH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL252C", "map_id": "YPL252C", "name": "YAH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10772851", "map_id": "none", "name": "FDX1,FDX2 (reduced)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:33738", "map_id": "CHEBI:33738", "name": "CHEBI:33738", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10774295", "map_id": "none", "name": "FDXR:FAD", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10771310", "map_id": "none", "name": "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_893599", "map_id": "CHEBI:29750", "name": "3IN-PYRA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10781200", "map_id": "none", "name": "HSD17B11 dehydrogenates EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10781197", "map_id": "none", "name": "Homologues of HSD17B11", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773448", "map_id": "none", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10773445", "map_id": "none", "name": "PIP4K2 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10787145", "map_id": "none", "name": "NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767030", "map_id": "none", "name": "NMNAT2:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10788787", "map_id": "none", "name": "PGM1:Mg2+ isomerises G6P to G1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788782", "map_id": "none", "name": "PGM1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10784736", "map_id": "none", "name": "NUDT12 hydrolyses NADH to NMNH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389620", "map_id": "CHEBI:456215", "name": "AMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6809289", "map_id": "CHEBI:74452", "name": "NMNH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10784733", "map_id": "P53164", "name": "NPY1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "YGL067W", "map_id": "YGL067W", "name": "NPY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767473", "map_id": "none", "name": "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_200492", "map_id": "CHEBI:15763", "name": "NAMN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_200499", "map_id": "CHEBI:18304", "name": "NAAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10767470", "map_id": "none", "name": "6xNMNAT1:6xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10773601", "map_id": "none", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10773598", "map_id": "none", "name": "SYNJ/INPP5(1)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q12271", "map_id": "Q12271", "name": "INP53", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR109W", "map_id": "YOR109W", "name": "INP53", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40559", "map_id": "P40559", "name": "INP51", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL002C", "map_id": "YIL002C", "name": "INP51", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10774843", "map_id": "none", "name": "HLCS biotinylates ACACA:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10774841", "map_id": "none", "name": "ACACA:2Mn2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32874", "map_id": "P32874", "name": "HFA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR207C", "map_id": "YMR207C", "name": "HFA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764051", "map_id": "none", "name": "Btn-ACACA:2Mn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10774830", "map_id": "P48445", "name": "BPL1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YDL141W", "map_id": "YDL141W", "name": "BPL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771961", "map_id": "none", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10771945", "map_id": "none", "name": "MOCS3:Zn2+ (red.)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38820", "map_id": "P38820", "name": "UBA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR111W", "map_id": "YHR111W", "name": "UBA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10771950", "map_id": "none", "name": "MOCS3-S-S(1-):Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10771958", "map_id": "none", "name": "PXLP-K258-NFS1-2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P25374", "map_id": "P25374", "name": "NFS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCL017C", "map_id": "YCL017C", "name": "NFS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773561", "map_id": "none", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10773418", "map_id": "P38994", "name": "MSS4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10774121", "map_id": "none", "name": "Conversion of DHA-CoA to docosahexaenoic acid (DHA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_2066765", "map_id": "CHEBI:65132", "name": "DHA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_2066763", "map_id": "CHEBI:28125", "name": "DHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10773542", "map_id": "none", "name": "PI4P is dephosphorylated to PI by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10773511", "map_id": "none", "name": "SYNJs,OCRL", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10762104", "map_id": "none", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29510", "map_id": "CHEBI:15343", "name": "CH3CHO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10762101", "map_id": "none", "name": "ALDH1A1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P46367", "map_id": "P46367", "name": "ALD4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR374W", "map_id": "YOR374W", "name": "ALD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P54115", "map_id": "P54115", "name": "ALD6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL061W", "map_id": "YPL061W", "name": "ALD6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769022", "map_id": "none", "name": "Conversion of glyoxylate to oxalate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389678", "map_id": "CHEBI:16891", "name": "glyoxylate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_113535", "map_id": "CHEBI:15379", "name": "O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389819", "map_id": "CHEBI:16995", "name": "OX", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_113575", "map_id": "CHEBI:16240", "name": "H2O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10769016", "map_id": "none", "name": "HAO1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "P00175", "map_id": "P00175", "name": "CYB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CYB2", "map_id": "CYB2", "name": "CYB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767564", "map_id": "none", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_3632881", "map_id": "CHEBI:15756", "name": "PALM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10767561", "map_id": "none", "name": "ACSL1,3,5,6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P39518", "map_id": "P39518", "name": "FAA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER015W", "map_id": "YER015W", "name": "FAA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761112", "map_id": "none", "name": "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10761109", "map_id": "none", "name": "phosphoPFKFB1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32604", "map_id": "P32604", "name": "phospho-FBP26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL155C", "map_id": "YJL155C", "name": "phospho-FBP26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768062", "map_id": "none", "name": "N-acetylation of serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_209793", "map_id": "CHEBI:17697", "name": "Ac5HT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10768059", "map_id": "Q12447", "name": "PAA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YDR071C", "map_id": "YDR071C", "name": "PAA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10774508", "map_id": "none", "name": "ITPA hydrolyses dITP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2509835", "map_id": "CHEBI:61382", "name": "dITP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9731659", "map_id": "CHEBI:61194", "name": "dIMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10785581", "map_id": "none", "name": "NTPDase8 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9726186", "map_id": "none", "name": "AMP,GMP,IMP,CMP,TMP,UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10761792", "map_id": "none", "name": "3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30487", "map_id": "CHEBI:15793", "name": "3HAA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761789", "map_id": "none", "name": "KYNU dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q05979", "map_id": "Q05979", "name": "BNA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR231C", "map_id": "YLR231C", "name": "BNA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763309", "map_id": "none", "name": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500071", "map_id": "none", "name": "(d)GMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:57673", "map_id": "CHEBI:57673", "name": "CHEBI:57673", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500077", "map_id": "none", "name": "(d)GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10766758", "map_id": "none", "name": "Reduction of presqualene diphosphate to form squalene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191265", "map_id": "CHEBI:15442", "name": "PSQPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_191269", "map_id": "CHEBI:15440", "name": "SQNE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766755", "map_id": "none", "name": "FDFT:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P29704", "map_id": "P29704", "name": "ERG9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR190W", "map_id": "YHR190W", "name": "ERG9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766487", "map_id": "none", "name": "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_188458", "map_id": "CHEBI:15978", "name": "G3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_188451", "map_id": "CHEBI:57642", "name": "DHAP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10766484", "map_id": "P32191", "name": "GUT2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YIL155C", "map_id": "YIL155C", "name": "GUT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781600", "map_id": "none", "name": "ABHD4 hydrolyses NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5694568", "map_id": "CHEBI:61232", "name": "NAPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_5694580", "map_id": "CHEBI:52571", "name": "GPAEA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_5694567", "map_id": "CHEBI:22221", "name": "acyl group", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10781597", "map_id": "none", "name": "Homologues of ABHD4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q12385", "map_id": "Q12385", "name": "ICT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR099C", "map_id": "YLR099C", "name": "ICT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04623", "map_id": "Q04623", "name": "ECM18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR125C", "map_id": "YDR125C", "name": "ECM18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53264", "map_id": "P53264", "name": "CLD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR110W", "map_id": "YGR110W", "name": "CLD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53208", "map_id": "P53208", "name": "EAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR015C", "map_id": "YGR015C", "name": "EAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773609", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10773550", "map_id": "none", "name": "MTM1,MTMR1,MTMR3,MTMR6,MTMR14,SYNJ1,SYNJ2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10764056", "map_id": "none", "name": "Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29508", "map_id": "CHEBI:15531", "name": "Mal-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10764053", "map_id": "none", "name": "Btn-ACACA:2Mn2+ polymer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10771185", "map_id": "none", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_549167", "map_id": "CHEBI:17855", "name": "TAG", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10771182", "map_id": "Q08650", "name": "DGA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10763172", "map_id": "none", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_500742", "map_id": "CHEBI:246422", "name": "dUMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_9668967", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10763169", "map_id": "none", "name": "DUT trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P33317", "map_id": "P33317", "name": "DUT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR252W", "map_id": "YBR252W", "name": "DUT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761773", "map_id": "none", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_71112", "map_id": "CHEBI:15374", "name": "4aOH-BH4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_71129", "map_id": "CHEBI:20680", "name": "qDHB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761770", "map_id": "none", "name": "PCBD1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38744", "map_id": "P38744", "name": "PCBD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHL018W", "map_id": "YHL018W", "name": "PCBD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773002", "map_id": "none", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_1524103", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_1500580", "map_id": "CHEBI:16975", "name": "1-acyl LPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10764827", "map_id": "none", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10763105", "map_id": "none", "name": "PRPS1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38063", "map_id": "P38063", "name": "PRS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL068W", "map_id": "YBL068W", "name": "PRS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32895", "map_id": "P32895", "name": "PRS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL181W", "map_id": "YKL181W", "name": "PRS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38689", "map_id": "P38689", "name": "PRS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHL011C", "map_id": "YHL011C", "name": "PRS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12265", "map_id": "Q12265", "name": "PRS5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL061W", "map_id": "YOL061W", "name": "PRS5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38620", "map_id": "P38620", "name": "PRS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER099C", "map_id": "YER099C", "name": "PRS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10774851", "map_id": "none", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2995328", "map_id": "CHEBI:24480", "name": "heme O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10774848", "map_id": "P21592", "name": "COX10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YPL172C", "map_id": "YPL172C", "name": "COX10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761624", "map_id": "none", "name": "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_71847", "map_id": "CHEBI:28259", "name": "bHIB-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_573404", "map_id": "CHEBI:11805", "name": "bHIBA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10761621", "map_id": "P28817", "name": "EHD3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "YDR036C", "map_id": "YDR036C", "name": "EHD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767280", "map_id": "none", "name": "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767277", "map_id": "none", "name": "CYB5R3:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10785569", "map_id": "none", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8851462", "map_id": "none", "name": "CDP,GDP,IDP,UDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_8851461", "map_id": "none", "name": "CMP,GMP,IMP,UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10785566", "map_id": "none", "name": "NTPDase6:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10774119", "map_id": "none", "name": "Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_2066767", "map_id": "CHEBI:65139", "name": "delta2-THA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_2066766", "map_id": "CHEBI:65130", "name": "1-3-hydroxy-THA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10787695", "map_id": "none", "name": "PRODH2 oxidises HPRO to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6784215", "map_id": "CHEBI:18240", "name": "HPRO", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113597", "map_id": "CHEBI:16238", "name": "FAD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_164934", "map_id": "CHEBI:17877", "name": "FADH2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10781897", "map_id": "P09368", "name": "PUT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YLR142W", "map_id": "YLR142W", "name": "PUT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772003", "map_id": "none", "name": "2xPNPO:2xFMN oxidizes PDXP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_964952", "map_id": "CHEBI:28803", "name": "PDXP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10771152", "map_id": "none", "name": "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_548809", "map_id": "CHEBI:50570", "name": "TOD-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428139", "map_id": "CHEBI:15541", "name": "ST-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10771147", "map_id": "Q99190", "name": "TSC13", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YDL015C", "map_id": "YDL015C", "name": "TSC13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761763", "map_id": "none", "name": "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_70951", "map_id": "CHEBI:15753", "name": "aKADA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_70955", "map_id": "CHEBI:15524", "name": "GL-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10761760", "map_id": "none", "name": "lipo-aKGDH", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P20967", "map_id": "P20967", "name": "KGD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL125W", "map_id": "YIL125W", "name": "KGD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17460", "map_id": "CHEBI:17460", "name": "CHEBI:17460", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P19262", "map_id": "P19262", "name": "KGD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR148C", "map_id": "YDR148C", "name": "KGD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767016", "map_id": "none", "name": "NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767013", "map_id": "none", "name": "NADK:Zn2+ tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P21373", "map_id": "P21373", "name": "UTR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR049C", "map_id": "YJR049C", "name": "UTR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784758", "map_id": "none", "name": "MTMR12 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10784750", "map_id": "P47147", "name": "YMR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773465", "map_id": "P47147", "name": "YMR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10784756", "map_id": "none", "name": "MTMR2:MTMR12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10782032", "map_id": "none", "name": "AK6 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_6788813", "map_id": "none", "name": "(d)NMPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_6788807", "map_id": "none", "name": "(d)NDPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10782029", "map_id": "Q12055", "name": "FAP7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YDL166C", "map_id": "YDL166C", "name": "FAP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768262", "map_id": "none", "name": "LTA4 is hydolysed to LTB4 by LTA4H", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_265281", "map_id": "CHEBI:15651", "name": "LTA4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_266056", "map_id": "CHEBI:15647", "name": "LTB4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10787954", "map_id": "none", "name": "FAHD1:Zn2+ dimer hydrolyses OA to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10787951", "map_id": "none", "name": "FAHD1:Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P53889", "map_id": "P53889", "name": "FMP41", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL168C", "map_id": "YNL168C", "name": "FMP41", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784681", "map_id": "none", "name": "ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111353", "map_id": "CHEBI:28010", "name": "10-formyl-THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10784678", "map_id": "none", "name": "ALDH1L1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10784137", "map_id": "none", "name": "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6801458", "map_id": "CHEBI:15638", "name": "5,10-methenyl-THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10784132", "map_id": "P09440", "name": "MIS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "YBR084W", "map_id": "YBR084W", "name": "MIS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763379", "map_id": "none", "name": "FGAM + ATP => AIR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111369", "map_id": "CHEBI:147287", "name": "FGAM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111370", "map_id": "CHEBI:137981", "name": "AIR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10771277", "map_id": "none", "name": "(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_879997", "map_id": "CHEBI:32796", "name": "2HG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10771274", "map_id": "P46681", "name": "DLD2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "YDL178W", "map_id": "YDL178W", "name": "DLD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_880067", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10766543", "map_id": "none", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_189461", "map_id": "CHEBI:15379", "name": "O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189478", "map_id": "CHEBI:15435", "name": "PPGEN9", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189481", "map_id": "CHEBI:16240", "name": "H2O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189463", "map_id": "CHEBI:15430", "name": "PRIN9", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10766540", "map_id": "none", "name": "2xPPOX:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "P40012", "map_id": "P40012", "name": "HEM14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER014W", "map_id": "YER014W", "name": "HEM14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773316", "map_id": "none", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500603", "map_id": "CHEBI:16732", "name": "CDP-ETA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773313", "map_id": "none", "name": "PCYT2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P33412", "map_id": "P33412", "name": "ECT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR007W", "map_id": "YGR007W", "name": "ECT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773052", "map_id": "none", "name": "1-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524038", "map_id": "CHEBI:17984", "name": "acyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10772962", "map_id": "Q07560", "name": "CRD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YDL142C", "map_id": "YDL142C", "name": "CRD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768252", "map_id": "none", "name": "LTC4 is exported from the cytosol by ABCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_266066", "map_id": "CHEBI:16978", "name": "LTC4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_266013", "map_id": "CHEBI:16978", "name": "LTC4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10761148", "map_id": "none", "name": "DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30393", "map_id": "CHEBI:17378", "name": "GA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761145", "map_id": "none", "name": "TKFC:2Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P54838", "map_id": "P54838", "name": "DAK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML070W", "map_id": "YML070W", "name": "DAK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766599", "map_id": "none", "name": "UROS transforms HMB to URO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189407", "map_id": "CHEBI:15437", "name": "URO3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766596", "map_id": "P06174", "name": "HEM4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YOR278W", "map_id": "YOR278W", "name": "HEM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773148", "map_id": "none", "name": "MLCL is acylated to CL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1524069", "map_id": "CHEBI:60430", "name": "MLCL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1524081", "map_id": "CHEBI:28494", "name": "CL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10764105", "map_id": "P38226", "name": "CST26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10784649", "map_id": "none", "name": "ALDH3B2 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13977", "compartment_display": "lipid droplet" }, { "id": "species_6808468", "map_id": "CHEBI:17600", "name": "HXAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13977", "compartment_display": "lipid droplet", "complex": "false" }, { "id": "species_2453691", "map_id": "CHEBI:15756", "name": "PALM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13977", "compartment_display": "lipid droplet", "complex": "false" }, { "id": "species_10784646", "map_id": "Q04458", "name": "HFD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13977", "compartment_display": "lipid droplet", "complex": "false" }, { "id": "reaction_10773056", "map_id": "none", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10764653", "map_id": "none", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10787680", "map_id": "none", "name": "UCKL1 phosphorylates urindine, cytidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500759", "map_id": "none", "name": "Cyt-Rib, Ura-Rib", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500761", "map_id": "none", "name": "CMP, UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10787677", "map_id": "P27515", "name": "URK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YNR012W", "map_id": "YNR012W", "name": "URK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10762000", "map_id": "none", "name": "limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10761969", "map_id": "none", "name": "limit dextrin-glycogenin dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10776278", "map_id": "none", "name": "GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10776259", "map_id": "none", "name": "PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10787833", "map_id": "none", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6787326", "map_id": "CHEBI:11563", "name": "dR1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6787328", "map_id": "CHEBI:16132", "name": "dR5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761119", "map_id": "none", "name": "PGM2:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788340", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9022655", "map_id": "CHEBI:138490", "name": "5S,6S-epoxy-18(S)-HEPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9022660", "map_id": "CHEBI:137038", "name": "18(S)-RvE1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773563", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_1806205", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "species_1806259", "map_id": "CHEBI:16500", "name": "PI5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "reaction_10774859", "map_id": "none", "name": "COX15 transforms heme O to heme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2995348", "map_id": "CHEBI:24479", "name": "heme A", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10774856", "map_id": "P40086", "name": "COX15", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YER141W", "map_id": "YER141W", "name": "COX15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781907", "map_id": "none", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6784236", "map_id": "CHEBI:32812", "name": "4-OH-L-Glu", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6784229", "map_id": "CHEBI:17742", "name": "HOG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10773380", "map_id": "none", "name": "PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1614518", "map_id": "CHEBI:17482", "name": "L-Cystathionine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773377", "map_id": "none", "name": "PXLP-CBS tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P32582", "map_id": "P32582", "name": "CYS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR155W", "map_id": "YGR155W", "name": "CYS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775560", "map_id": "none", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775513", "map_id": "none", "name": "polyGlc-GYG1:GYS1-a tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10782009", "map_id": "none", "name": "HDHD1:Mg2+ dephosphorylates PURIDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6788291", "map_id": "CHEBI:18116", "name": "PURIDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6788290", "map_id": "CHEBI:17802", "name": "PURID", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10782006", "map_id": "none", "name": "HDHD1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q86ZR7", "map_id": "Q86ZR7", "name": "HDHD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL033W-A", "map_id": "YKL033W-A", "name": "HDHD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781636", "map_id": "none", "name": "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5696426", "map_id": "CHEBI:75627", "name": "ARACOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_192172", "map_id": "CHEBI:17984", "name": "Acyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_162743", "map_id": "CHEBI:57287", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_5696412", "map_id": "CHEBI:10036", "name": "arachidyl ester", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10781633", "map_id": "Q08650", "name": "DGA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10771046", "map_id": "none", "name": "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_70115", "map_id": "CHEBI:17925", "name": "Glc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10771043", "map_id": "none", "name": "GLUT1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10782630", "map_id": "none", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6793610", "map_id": "CHEBI:26833", "name": "S", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10782620", "map_id": "P39726", "name": "GCV3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6793613", "map_id": "CHEBI:17319", "name": "5dAde", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_379705", "map_id": "CHEBI:57844", "name": "L-Met", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10782627", "map_id": "none", "name": "LIAS:2(4Fe-4S)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P32875", "map_id": "P32875", "name": "LIP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR196C", "map_id": "YOR196C", "name": "LIP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769056", "map_id": "none", "name": "HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_390249", "map_id": "CHEBI:52975", "name": "trans-2,3-dehydrohexacosanoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_390248", "map_id": "CHEBI:64972", "name": "3-hydroxyhexacosanoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10772015", "map_id": "none", "name": "PSPH:Mg2+ dimer dephosphorylates O-P-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_936706", "map_id": "CHEBI:15811", "name": "O-P-Ser", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772012", "map_id": "none", "name": "PSPH:Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P42941", "map_id": "P42941", "name": "SER2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR208W", "map_id": "YGR208W", "name": "SER2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766979", "map_id": "none", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10766976", "map_id": "P38913", "name": "FAD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YDL045C", "map_id": "YDL045C", "name": "FAD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781999", "map_id": "none", "name": "HAO2 tetramer oxidises 2OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_6787810", "map_id": "CHEBI:65101", "name": "2OH-PALM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6787814", "map_id": "CHEBI:86988", "name": "2oxo-PALM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10781996", "map_id": "none", "name": "HAO2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "reaction_10761476", "map_id": "none", "name": "argininosuccinate <=> fumarate + arginine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_34575", "map_id": "CHEBI:15682", "name": "ARSUA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761473", "map_id": "none", "name": "ASL tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P04076", "map_id": "P04076", "name": "ARG4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR018C", "map_id": "YHR018C", "name": "ARG4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766690", "map_id": "none", "name": "Squalene is oxidized to its epoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10766687", "map_id": "none", "name": "SQLE:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P32476", "map_id": "P32476", "name": "ERG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR175C", "map_id": "YGR175C", "name": "ERG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761732", "map_id": "none", "name": "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_70958", "map_id": "CHEBI:57292", "name": "SUCC-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10761729", "map_id": "none", "name": "SUCLA2:SUCLG1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P53598", "map_id": "P53598", "name": "LSC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR142W", "map_id": "YOR142W", "name": "LSC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53312", "map_id": "P53312", "name": "LSC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR244C", "map_id": "YGR244C", "name": "LSC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786830", "map_id": "none", "name": "SLC25A19 transports ThDP from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_8878387", "map_id": "CHEBI:58937", "name": "ThDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10786827", "map_id": "P53257", "name": "TPC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YGR096W", "map_id": "YGR096W", "name": "TPC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765677", "map_id": "none", "name": "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29878", "map_id": "CHEBI:16897", "name": "E4P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29882", "map_id": "CHEBI:15721", "name": "SH7P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761886", "map_id": "none", "name": "TALDO1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P15019", "map_id": "P15019", "name": "TAL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR354C", "map_id": "YLR354C", "name": "TAL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767455", "map_id": "none", "name": "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_201023", "map_id": "CHEBI:17126", "name": "CAR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_201034", "map_id": "CHEBI:17490", "name": "L-PCARN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_549207", "map_id": "CHEBI:17126", "name": "CAR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_201050", "map_id": "CHEBI:17490", "name": "L-PCARN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10767452", "map_id": "Q12289", "name": "CRC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YOR100C", "map_id": "YOR100C", "name": "CRC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763358", "map_id": "none", "name": "FAICAR => IMP + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111427", "map_id": "CHEBI:58467", "name": "FAICAR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10763355", "map_id": "none", "name": "ATIC dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38009", "map_id": "P38009", "name": "ADE17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR120C", "map_id": "YMR120C", "name": "ADE17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773353", "map_id": "none", "name": "Uncoupled eNOS favours the formation of superoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1222424", "map_id": "CHEBI:18421", "name": "O2.-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10788219", "map_id": "none", "name": "PXLP-K56-SRR dimer deaminates D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_376186", "map_id": "CHEBI:16523", "name": "D-Ser", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10786160", "map_id": "none", "name": "FITM1, FITM2 bind TAGs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10786156", "map_id": "none", "name": "FITM1,FITM2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q06676", "map_id": "Q06676", "name": "YFT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR319C", "map_id": "YDR319C", "name": "YFT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53012", "map_id": "P53012", "name": "SCS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL126W", "map_id": "YGL126W", "name": "SCS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10786158", "map_id": "none", "name": "(FITM1,FITM2):TAGs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10767260", "map_id": "none", "name": "SLC2A1,3 transports DeHA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_198852", "map_id": "CHEBI:58539", "name": "DeHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_198827", "map_id": "CHEBI:58539", "name": "DeHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10767257", "map_id": "none", "name": "SLC2A1,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10762137", "map_id": "none", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113532", "map_id": "CHEBI:15343", "name": "CH3CHO", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113539", "map_id": "CHEBI:30089", "name": "CH3COO-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10763070", "map_id": "none", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111628", "map_id": "CHEBI:32814", "name": "N-carb-L-Asp", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76630", "map_id": "CHEBI:30864", "name": "(S)-DHO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10769862", "map_id": "none", "name": "SPHK1 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428193", "map_id": "CHEBI:16393", "name": "SPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10785507", "map_id": "none", "name": "NTPDase1 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10785501", "map_id": "none", "name": "NTPDase1:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788350", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024768", "map_id": "CHEBI:138646", "name": "7S(8)-epoxy-17(S)-HDHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024759", "map_id": "none", "name": "RvD1, RvD2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:81565", "map_id": "CHEBI:81565", "name": "CHEBI:81565", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:81564", "map_id": "CHEBI:81564", "name": "CHEBI:81564", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784145", "map_id": "none", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6803257", "map_id": "CHEBI:63907", "name": "5-formyl-THFPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_200640", "map_id": "CHEBI:65049", "name": "5,10-methenyl-THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10784142", "map_id": "P40099", "name": "FAU1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YER183C", "map_id": "YER183C", "name": "FAU1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10777793", "map_id": "none", "name": "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_5490253", "map_id": "none", "name": "AFXBO-SG,AFNBO-SG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:78587", "map_id": "CHEBI:78587", "name": "CHEBI:78587", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:78581", "map_id": "CHEBI:78581", "name": "CHEBI:78581", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5490235", "map_id": "none", "name": "AFXBO-CG,AFNBO-CG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:78579", "map_id": "CHEBI:78579", "name": "CHEBI:78579", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:78584", "map_id": "CHEBI:78584", "name": "CHEBI:78584", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784767", "map_id": "none", "name": "SBF1 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10784763", "map_id": "P47147", "name": "YMR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10773553", "map_id": "none", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10771041", "map_id": "none", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_482807", "map_id": "none", "name": "(d)NTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_482803", "map_id": "none", "name": "(d)NDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10771036", "map_id": "none", "name": "NME4 hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10767033", "map_id": "none", "name": "NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10765667", "map_id": "none", "name": "AMP binds to gamma subunit of AMP kinase heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765661", "map_id": "none", "name": "AMPK heterotrimer (inactive)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10765665", "map_id": "none", "name": "AMPK heterotrimer:AMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10787120", "map_id": "none", "name": "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8932979", "map_id": "CHEBI:33384", "name": "L-Ser", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10787109", "map_id": "Q12116", "name": "TMS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YDR105C", "map_id": "YDR105C", "name": "TMS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764159", "map_id": "none", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_76108", "map_id": "CHEBI:29089", "name": "1,2-daG3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10764152", "map_id": "P32567", "name": "PAH1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10769052", "map_id": "none", "name": "3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_390241", "map_id": "CHEBI:52977", "name": "3-ketohexacosanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_390246", "map_id": "CHEBI:52974", "name": "tetracosanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10769049", "map_id": "P27796", "name": "POT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10773616", "map_id": "none", "name": "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1806230", "map_id": "CHEBI:16152", "name": "PI(3,4)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10773611", "map_id": "P53916", "name": "TEP1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10767527", "map_id": "none", "name": "MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767483", "map_id": "none", "name": "MTHFD1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P07245", "map_id": "P07245", "name": "ADE3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR204W", "map_id": "YGR204W", "name": "ADE3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771991", "map_id": "none", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_965053", "map_id": "CHEBI:16709", "name": "PDX", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773140", "map_id": "none", "name": "MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524083", "map_id": "CHEBI:16038", "name": "PE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524089", "map_id": "CHEBI:29017", "name": "1-acyl LPE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10773208", "map_id": "none", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10773205", "map_id": "none", "name": "CEPT1/EPT1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10784770", "map_id": "none", "name": "PI3P is dephosphorylated to PI by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5676030", "map_id": "CHEBI:26034", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10788208", "map_id": "none", "name": "SDS dimers:PXLP dehydrate L-Thr to 2AA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_351990", "map_id": "CHEBI:57926", "name": "L-Thr", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9014643", "map_id": "CHEBI:58020", "name": "2AA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10788205", "map_id": "none", "name": "PXLP-SDS dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P25379", "map_id": "P25379", "name": "CHA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCL064C", "map_id": "YCL064C", "name": "CHA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769066", "map_id": "none", "name": "acetyl-CoA + H2O => acetate + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_390305", "map_id": "CHEBI:15366", "name": "CH3COO-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10766152", "map_id": "none", "name": "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10766147", "map_id": "none", "name": "ETF:FAD", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q12480", "map_id": "Q12480", "name": "AIM45", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR004C", "map_id": "YPR004C", "name": "AIM45", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P42940", "map_id": "P42940", "name": "CIR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR207C", "map_id": "YGR207C", "name": "CIR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10766149", "map_id": "none", "name": "ETF:FADH2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10773039", "map_id": "none", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10772026", "map_id": "none", "name": "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_977329", "map_id": "CHEBI:30933", "name": "3POPA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772023", "map_id": "none", "name": "PXLP-K200-PSAT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P33330", "map_id": "P33330", "name": "SER1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR184W", "map_id": "YOR184W", "name": "SER1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766425", "map_id": "none", "name": "ribose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10761876", "map_id": "Q12189", "name": "RKI1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YOR095C", "map_id": "YOR095C", "name": "RKI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10762017", "map_id": "none", "name": "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762014", "map_id": "none", "name": "glycogen-glycogenin-2 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10761967", "map_id": "none", "name": "limit dextrin-glycogenin-2 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773054", "map_id": "none", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10774286", "map_id": "none", "name": "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1131972", "map_id": "CHEBI:57967", "name": "ADP-D-ribose", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10774283", "map_id": "none", "name": "NUDT5 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q01976", "map_id": "Q01976", "name": "YSA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR111C", "map_id": "YBR111C", "name": "YSA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769044", "map_id": "none", "name": "3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389982", "map_id": "CHEBI:63914", "name": "3-hydroxypristanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389996", "map_id": "CHEBI:15371", "name": "3-ketopristanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10763073", "map_id": "none", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10782024", "map_id": "none", "name": "AK4 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6788802", "map_id": "none", "name": "(d)NMPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_6788801", "map_id": "none", "name": "(d)NDPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10782021", "map_id": "P26364", "name": "ADK2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10773472", "map_id": "none", "name": "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "species_1806198", "map_id": "CHEBI:17283", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "species_1806195", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "reaction_10769935", "map_id": "none", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428682", "map_id": "CHEBI:16393", "name": "SPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10768244", "map_id": "none", "name": "GGT1, 5 dimers hydrolyse LTC4 to LTD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_266074", "map_id": "CHEBI:28666", "name": "LTD4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10768241", "map_id": "none", "name": "GGT1, 5 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10776221", "map_id": "none", "name": "GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10776213", "map_id": "none", "name": "PPP1R3C:glycogen-GYG2:GYS2-a tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10776218", "map_id": "none", "name": "PPP1R3C:phosphoglycogen-GYG2:GYS2-a tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10771993", "map_id": "none", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_965131", "map_id": "CHEBI:17310", "name": "PXL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773571", "map_id": "none", "name": "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1806159", "map_id": "CHEBI:17283", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10773568", "map_id": "P32368", "name": "SAC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10767728", "map_id": "none", "name": "N-myristoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_184174", "map_id": "CHEBI:15532", "name": "MYS-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10767726", "map_id": "P16603", "name": "NCP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773396", "map_id": "none", "name": "PXLP-K212-CTH cleaves L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10761549", "map_id": "none", "name": "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_113567", "map_id": "CHEBI:16349", "name": "L-Cit", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10761546", "map_id": "none", "name": "Homologues of SLC25A15", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q12375", "map_id": "Q12375", "name": "ORT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR130C", "map_id": "YOR130C", "name": "ORT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38087", "map_id": "P38087", "name": "YMC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR104W", "map_id": "YBR104W", "name": "YMC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32331", "map_id": "P32331", "name": "YMC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR058W", "map_id": "YPR058W", "name": "YMC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766880", "map_id": "none", "name": "ABCC3 transports bile salts from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_194156", "map_id": "none", "name": "bile salts and acids", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:17687", "map_id": "CHEBI:17687", "name": "CHEBI:17687", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16755", "map_id": "CHEBI:16755", "name": "CHEBI:16755", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16525", "map_id": "CHEBI:16525", "name": "CHEBI:16525", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28865", "map_id": "CHEBI:28865", "name": "CHEBI:28865", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:36274", "map_id": "CHEBI:36274", "name": "CHEBI:36274", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_192483", "map_id": "none", "name": "bile salts and acids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:9407", "map_id": "CHEBI:9407", "name": "CHEBI:9407", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10766877", "map_id": "P53049", "name": "YOR1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10764658", "map_id": "none", "name": "ADP + ADP <=> AMP + ATP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764655", "map_id": "P07170", "name": "ADK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "reaction_10785452", "map_id": "none", "name": "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8848577", "map_id": "CHEBI:16125", "name": "HXOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8848499", "map_id": "CHEBI:75584", "name": "PALM-PALM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10781638", "map_id": "Q08650", "name": "DGA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10766928", "map_id": "none", "name": "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193103", "map_id": "CHEBI:16581", "name": "PREG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_196344", "map_id": "CHEBI:63837", "name": "pregn-5-ene-3,20-dione", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10761446", "map_id": "none", "name": "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113561", "map_id": "CHEBI:28938", "name": "NH4+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29896", "map_id": "CHEBI:17544", "name": "HCO3-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29676", "map_id": "CHEBI:58228", "name": "CAP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10761443", "map_id": "P07259", "name": "URA2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10764500", "map_id": "none", "name": "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500173", "map_id": "none", "name": "Ade-Rib, dA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:17256", "map_id": "CHEBI:17256", "name": "CHEBI:17256", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500088", "map_id": "none", "name": "(d)AMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10764497", "map_id": "none", "name": "ADK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P47143", "map_id": "P47143", "name": "ADO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR105W", "map_id": "YJR105W", "name": "ADO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781620", "map_id": "none", "name": "ALDH3B1 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_428663", "map_id": "CHEBI:17600", "name": "HXAL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10781617", "map_id": "Q04458", "name": "HFD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10773589", "map_id": "none", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10773586", "map_id": "none", "name": "PIP4K2/5K1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10761466", "map_id": "none", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29514", "map_id": "CHEBI:16199", "name": "Urea", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761463", "map_id": "none", "name": "ARG1 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10785455", "map_id": "none", "name": "AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_30209", "map_id": "CHEBI:17336", "name": "atROL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2534407", "map_id": "CHEBI:17616", "name": "atR-PALM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10766738", "map_id": "none", "name": "Mevalonate is phosphorylated to mevalonate-5-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191424", "map_id": "CHEBI:17710", "name": "MVA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_191296", "map_id": "CHEBI:17436", "name": "MVA5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766735", "map_id": "none", "name": "MVK dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P07277", "map_id": "P07277", "name": "ERG12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR208W", "map_id": "YMR208W", "name": "ERG12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772862", "map_id": "none", "name": "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10772838", "map_id": "none", "name": "2 Iron:FXN:NFS1:ISD11:ISCU", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q6Q560", "map_id": "Q6Q560", "name": "ISD11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER048W-A", "map_id": "YER048W-A", "name": "ISD11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q07540", "map_id": "Q07540", "name": "YFH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFH1", "map_id": "YFH1", "name": "YFH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03020", "map_id": "Q03020", "name": "ISU1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL135W", "map_id": "YPL135W", "name": "ISU1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_379721", "map_id": "CHEBI:35235", "name": "L-Cys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10772853", "map_id": "none", "name": "FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10766930", "map_id": "none", "name": "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193124", "map_id": "CHEBI:28750", "name": "17aHPREG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10774126", "map_id": "none", "name": "Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_2066762", "map_id": "CHEBI:65131", "name": "1-3-oxo-THA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10761825", "map_id": "none", "name": "BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_31369", "map_id": "CHEBI:16244", "name": "TEABT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_30235", "map_id": "CHEBI:17126", "name": "CAR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29434", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761822", "map_id": "none", "name": "BBOX1:AscH-:Fe2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P23180", "map_id": "P23180", "name": "AIM17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHL021C", "map_id": "YHL021C", "name": "AIM17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761669", "map_id": "none", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10761666", "map_id": "none", "name": "CS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P00890", "map_id": "P00890", "name": "CIT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CIT1", "map_id": "CIT1", "name": "CIT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10788352", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024577", "map_id": "CHEBI:138612", "name": "4S(5)-epoxy-17(R)-HDHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024570", "map_id": "none", "name": "AT-RvD3, AT-RvD4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:138616", "map_id": "CHEBI:138616", "name": "CHEBI:138616", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:138615", "map_id": "CHEBI:138615", "name": "CHEBI:138615", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10764963", "map_id": "none", "name": "PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500244", "map_id": "none", "name": "R1P, dRibP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_112016", "map_id": "CHEBI:57720", "name": "R1P", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "CHEBI:58576", "map_id": "CHEBI:58576", "name": "CHEBI:58576", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500245", "map_id": "none", "name": "G, dG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:17172", "map_id": "CHEBI:17172", "name": "CHEBI:17172", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10763557", "map_id": "none", "name": "PNP trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10778389", "map_id": "none", "name": "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_964746", "map_id": "CHEBI:17925", "name": "Glc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10778386", "map_id": "none", "name": "SLC2A1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10773283", "map_id": "none", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10773280", "map_id": "none", "name": "CDS1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P38221", "map_id": "P38221", "name": "CDS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR029C", "map_id": "YBR029C", "name": "CDS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786171", "map_id": "none", "name": "HSD17B13 binds lipid droplets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8866926", "map_id": "none", "name": "lipid droplet", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13977", "compartment_display": "lipid droplet", "complex": "true" }, { "id": "CHEBI:16247", "map_id": "CHEBI:16247", "name": "CHEBI:16247", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10786169", "map_id": "none", "name": "HSD17B13:lipid droplet", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13977", "compartment_display": "lipid droplet", "complex": "true" }, { "id": "reaction_10766710", "map_id": "none", "name": "HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191293", "map_id": "CHEBI:57286", "name": "ACA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_191374", "map_id": "CHEBI:43074", "name": "bHMG-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10766707", "map_id": "P54839", "name": "ERG13", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10761158", "map_id": "none", "name": "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29452", "map_id": "CHEBI:18307", "name": "UDP-Gal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761155", "map_id": "none", "name": "GALE:NAD+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P04397", "map_id": "P04397", "name": "GAL10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR019C", "map_id": "YBR019C", "name": "GAL10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773537", "map_id": "none", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10773532", "map_id": "none", "name": "PIK3C3:Mn2+:PIK3R4:Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10781258", "map_id": "none", "name": "FA2H hydroxylates CERA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_428256", "map_id": "CHEBI:17761", "name": "CERA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_5693768", "map_id": "CHEBI:85781", "name": "2HCERA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10781255", "map_id": "Q03529", "name": "SCS7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YMR272C", "map_id": "YMR272C", "name": "SCS7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786994", "map_id": "none", "name": "ALPI dimer hydrolyses phosphate monoesters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8878780", "map_id": "CHEBI:7794", "name": "phosphate monoester", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8878776", "map_id": "CHEBI:30879", "name": "Alcohol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10786991", "map_id": "none", "name": "ALPI:2Ca2+:Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10785449", "map_id": "none", "name": "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500594", "map_id": "CHEBI:17855", "name": "TAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10785444", "map_id": "Q08650", "name": "DGA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10784665", "map_id": "none", "name": "ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6808499", "map_id": "CHEBI:28010", "name": "10-formyl-THFPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10784662", "map_id": "none", "name": "ADH1L2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10764630", "map_id": "none", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764627", "map_id": "none", "name": "UCK2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q12084", "map_id": "Q12084", "name": "DAS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR020C", "map_id": "YDR020C", "name": "DAS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773579", "map_id": "none", "name": "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "reaction_10761634", "map_id": "none", "name": "lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_29444", "map_id": "CHEBI:32551", "name": "L-Lys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10761228", "map_id": "none", "name": "HK1,2,3,GCK phosphorylate Glc to form G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10761225", "map_id": "none", "name": "glucokinase and hexokinases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788344", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024602", "map_id": "CHEBI:138613", "name": "7S(8)-epoxy-17(R)-HDHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024574", "map_id": "none", "name": "AT-RvD1, AT-RvD2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:138179", "map_id": "CHEBI:138179", "name": "CHEBI:138179", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:138614", "map_id": "CHEBI:138614", "name": "CHEBI:138614", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766553", "map_id": "none", "name": "UROD decarboxylates URO3 to COPRO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189455", "map_id": "CHEBI:15439", "name": "COPRO3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10766603", "map_id": "none", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10766560", "map_id": "none", "name": "8x(ALAD:Zn2+)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_190173", "map_id": "CHEBI:27889", "name": "Pb2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10766601", "map_id": "none", "name": "8xALAD:Pb2+:Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10761871", "map_id": "none", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10766563", "map_id": "none", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189489", "map_id": "CHEBI:356416", "name": "dALA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10766915", "map_id": "none", "name": "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194657", "map_id": "CHEBI:63844", "name": "4CZYMOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_194661", "map_id": "CHEBI:52386", "name": "ZYMONE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10766887", "map_id": "P53199", "name": "ERG26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10774123", "map_id": "none", "name": "Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "reaction_10784308", "map_id": "none", "name": "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8866401", "map_id": "CHEBI:57930", "name": "NDP(3-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10784305", "map_id": "none", "name": "NME1:NME3 heterohexamer, NME2P1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10784740", "map_id": "none", "name": "MTMR6 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10773548", "map_id": "P47147", "name": "YMR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10784738", "map_id": "none", "name": "MTMR6:MTMR9", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10763122", "map_id": "none", "name": "dCMP + H2O => dUMP + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10763119", "map_id": "none", "name": "DCTD hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P06773", "map_id": "P06773", "name": "DCD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR144C", "map_id": "YHR144C", "name": "DCD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769900", "map_id": "none", "name": "sphinganine 1-phosphate => phosphoethanolamine + hexadecanal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10770866", "map_id": "none", "name": "isocitrate <=> citrate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10761657", "map_id": "P19414", "name": "ACO1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10766533", "map_id": "none", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_189411", "map_id": "CHEBI:15439", "name": "COPRO3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189480", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10766530", "map_id": "none", "name": "2xCPO", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "P11353", "map_id": "P11353", "name": "HEM13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR044W", "map_id": "YDR044W", "name": "HEM13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763393", "map_id": "none", "name": "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111292", "map_id": "CHEBI:58681", "name": "PRA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10771060", "map_id": "none", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10771057", "map_id": "none", "name": "CTPS2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P28274", "map_id": "P28274", "name": "URA7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL039C", "map_id": "YBL039C", "name": "URA7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38627", "map_id": "P38627", "name": "URA8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR103W", "map_id": "YJR103W", "name": "URA8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784318", "map_id": "none", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6807473", "map_id": "CHEBI:64085", "name": "R-NADPHX", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10784315", "map_id": "none", "name": "APOA1BP dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P40165", "map_id": "P40165", "name": "NNR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL200C", "map_id": "YNL200C", "name": "NNR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10778609", "map_id": "none", "name": "SORD tetramer oxidizes xylitol to D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5660033", "map_id": "CHEBI:17151", "name": "xylitol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773555", "map_id": "none", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "reaction_10773582", "map_id": "none", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10775627", "map_id": "none", "name": "Cytoslic carboxylases translocate to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10774825", "map_id": "none", "name": "4x(Btn-PC:Mn2+)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10774951", "map_id": "none", "name": "4x(Btn-PC:Mn2+)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10772944", "map_id": "none", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498728", "map_id": "CHEBI:17389", "name": "2-MAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1500593", "map_id": "CHEBI:35366", "name": "fatty acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10772941", "map_id": "none", "name": "MGLL dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P28321", "map_id": "P28321", "name": "YJU3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766885", "map_id": "none", "name": "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194735", "map_id": "CHEBI:63842", "name": "4C4MZYMOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10766882", "map_id": "P53045", "name": "ERG25", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10766847", "map_id": "none", "name": "Pregn-5-ene-3,20-dione isomerizes to progesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193055", "map_id": "CHEBI:17026", "name": "P4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10761580", "map_id": "none", "name": "PRODH oxidises L-Pro to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10761577", "map_id": "P09368", "name": "PUT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10768933", "map_id": "none", "name": "2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389594", "map_id": "CHEBI:15475", "name": "3S2HPhy-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389578", "map_id": "CHEBI:15522", "name": "FOR-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10768930", "map_id": "none", "name": "HACL1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "P39994", "map_id": "P39994", "name": "PXP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL020C", "map_id": "YEL020C", "name": "PXP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772867", "map_id": "none", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10772865", "map_id": "none", "name": "FXN:ISD11:NFS1:ISCU", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_113531", "map_id": "CHEBI:29033", "name": "Fe2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10767499", "map_id": "none", "name": "MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10774100", "map_id": "none", "name": "Translocation of tetracosapentaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2046050", "map_id": "CHEBI:63546", "name": "TPA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_211579", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_2046055", "map_id": "CHEBI:63546", "name": "TPA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_5228339", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_211606", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10768821", "map_id": "P41909", "name": "PXA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "false" }, { "id": "reaction_10787692", "map_id": "none", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8955759", "map_id": "CHEBI:18148", "name": "G1,6BP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761123", "map_id": "none", "name": "PGM2L1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10784147", "map_id": "none", "name": "MTHFD1L transforms 10-formyl-THF to HCOOH and THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5389850", "map_id": "CHEBI:15637", "name": "10-formyl-THF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6801451", "map_id": "CHEBI:30751", "name": "HCOOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10781645", "map_id": "none", "name": "MTHFD1L dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10770911", "map_id": "none", "name": "arginine + H2O => ornithine + urea [ARG2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_374061", "map_id": "CHEBI:16199", "name": "Urea", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10770908", "map_id": "none", "name": "ARG2 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10766849", "map_id": "none", "name": "HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176626", "map_id": "CHEBI:28689", "name": "DHEA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10769061", "map_id": "none", "name": "propionyl-CoA + carnitine => propionylcarnitine + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_192314", "map_id": "CHEBI:15539", "name": "propionyl CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_390274", "map_id": "CHEBI:28867", "name": "Propionylcarnitine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10763317", "map_id": "none", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10763314", "map_id": "P38625", "name": "GUA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10781076", "map_id": "none", "name": "ADH5 oxidises S-HMGSH to S-FGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5692221", "map_id": "CHEBI:48926", "name": "S-HMGSH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5692249", "map_id": "CHEBI:16225", "name": "S-FGSH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10781073", "map_id": "none", "name": "ADH5:2xZn2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10767529", "map_id": "none", "name": "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10774098", "map_id": "none", "name": "Translocation of tetracosahexaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_2046054", "map_id": "CHEBI:63540", "name": "THA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046047", "map_id": "CHEBI:63540", "name": "THA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10767537", "map_id": "none", "name": "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10769032", "map_id": "none", "name": "ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389893", "map_id": "CHEBI:64039", "name": "(2S) Pristanoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389894", "map_id": "CHEBI:63803", "name": "trans-2,3-dehydropristanoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10769029", "map_id": "none", "name": "ACOXL:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "P13711", "map_id": "P13711", "name": "POX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL205W", "map_id": "YGL205W", "name": "POX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766890", "map_id": "none", "name": "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194667", "map_id": "CHEBI:50593", "name": "dh4MZYMOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10764323", "map_id": "none", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764320", "map_id": "none", "name": "AMPD tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10761802", "map_id": "none", "name": "3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_36027", "map_id": "CHEBI:29044", "name": "ACS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10761799", "map_id": "none", "name": "HAAO", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P47096", "map_id": "P47096", "name": "BNA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR025C", "map_id": "YJR025C", "name": "BNA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765675", "map_id": "none", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10764091", "map_id": "P33333", "name": "SLC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10779627", "map_id": "none", "name": "AADAC deacetylates PHEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5689006", "map_id": "CHEBI:8050", "name": "PHEN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5688995", "map_id": "CHEBI:85505", "name": "4-ethoxyaniline", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5689001", "map_id": "CHEBI:40574", "name": "acetyl group", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10779624", "map_id": "P53324", "name": "SAY1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10781992", "map_id": "none", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10763550", "map_id": "none", "name": "APRT catalyzes the conversion of adenine to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10763547", "map_id": "none", "name": "APRT dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10766581", "map_id": "none", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_189466", "map_id": "CHEBI:356416", "name": "dALA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10766578", "map_id": "none", "name": "ALAS1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P09950", "map_id": "P09950", "name": "HEM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR232W", "map_id": "YDR232W", "name": "HEM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787970", "map_id": "none", "name": "VDAC1 transports PYR from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9012375", "map_id": "CHEBI:15361", "name": "PYR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10777036", "map_id": "none", "name": "Homologues of VDAC1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "P04840", "map_id": "P04840", "name": "POR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "POR1", "map_id": "POR1", "name": "POR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40478", "map_id": "P40478", "name": "POR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL114C", "map_id": "YIL114C", "name": "POR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10780397", "map_id": "none", "name": "Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_5690520", "map_id": "none", "name": "MCFA-CoA, LCFA-CoA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "CHEBI:33184", "map_id": "CHEBI:33184", "name": "CHEBI:33184", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:61907", "map_id": "CHEBI:61907", "name": "CHEBI:61907", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5690539", "map_id": "none", "name": "MCFA, LCFA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "CHEBI:59554", "map_id": "CHEBI:59554", "name": "CHEBI:59554", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10761921", "map_id": "none", "name": "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10773344", "map_id": "none", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1498751", "map_id": "CHEBI:16000", "name": "ETA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10773341", "map_id": "none", "name": "CHK/ETNK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10769039", "map_id": "none", "name": "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_10769036", "map_id": "none", "name": "ACOX3:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "reaction_10769019", "map_id": "none", "name": "HAO1 tetramer oxidizes glycolate to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389822", "map_id": "CHEBI:29805", "name": "glycolate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10785562", "map_id": "none", "name": "NTPDase5 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8936165", "map_id": "none", "name": "ADP,GDP,CDP,UDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_8851369", "map_id": "none", "name": "AMP,GMP,CMP,UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10785559", "map_id": "none", "name": "NPTDase5:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10773047", "map_id": "none", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10774299", "map_id": "none", "name": "NADPH transfers electrons to FDXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10761456", "map_id": "none", "name": "carbamoyl phosphate + ornithine => citrulline + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10761453", "map_id": "none", "name": "OTC trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P05150", "map_id": "P05150", "name": "ARG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL088W", "map_id": "YJL088W", "name": "ARG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763572", "map_id": "none", "name": "Guanine + H2O => Xanthine + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30064", "map_id": "CHEBI:17712", "name": "XAN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10763569", "map_id": "none", "name": "GDA dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q07729", "map_id": "Q07729", "name": "GUD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL238C", "map_id": "YDL238C", "name": "GUD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773257", "map_id": "none", "name": "PG and CDP-DAG are converted to CL by CRLS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524064", "map_id": "CHEBI:17962", "name": "CDP-DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524067", "map_id": "CHEBI:60377", "name": "cytidine 5'-monophosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10785439", "map_id": "none", "name": "DBI, ACBD7 bind MCFA-CoA and LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_8848288", "map_id": "none", "name": "MCFA-CoA, LCFA-CoA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "species_10785433", "map_id": "P31787", "name": "ACB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10785437", "map_id": "none", "name": "DBI,ACBD7:MCFA-CoA,LCFA-CoA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10765739", "map_id": "none", "name": "Electron transfer from ubiquinol to cytochrome c of complex III", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_76633", "map_id": "CHEBI:17976", "name": "QH2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10765569", "map_id": "none", "name": "Cytochrome c (oxidised)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "CHEBI:38574", "map_id": "CHEBI:38574", "name": "CHEBI:38574", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_73663", "map_id": "CHEBI:46245", "name": "CoQ", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10765567", "map_id": "none", "name": "Cytochrome c (reduced)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "CHEBI:38573", "map_id": "CHEBI:38573", "name": "CHEBI:38573", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10765736", "map_id": "none", "name": "Ubiquinol-cytochrome c reductase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P11914", "map_id": "P11914", "name": "MAS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MAS2", "map_id": "MAS2", "name": "MAS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00128", "map_id": "P00128", "name": "QCR7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR529C", "map_id": "YDR529C", "name": "QCR7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P10507", "map_id": "P10507", "name": "MAS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "MAS1", "map_id": "MAS1", "name": "MAS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P07256", "map_id": "P07256", "name": "COR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL045C", "map_id": "YBL045C", "name": "COR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P08067", "map_id": "P08067", "name": "RIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL024W", "map_id": "YEL024W", "name": "RIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00163", "map_id": "P00163", "name": "COB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0105", "map_id": "Q0105", "name": "COB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P07143", "map_id": "P07143", "name": "CYT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CYT1", "map_id": "CYT1", "name": "CYT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22289", "map_id": "P22289", "name": "QCR9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR183C", "map_id": "YGR183C", "name": "QCR9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00127", "map_id": "P00127", "name": "QCR6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFR033C", "map_id": "YFR033C", "name": "QCR6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P08525", "map_id": "P08525", "name": "QCR8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL166W", "map_id": "YJL166W", "name": "QCR8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10766892", "map_id": "none", "name": "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194723", "map_id": "CHEBI:63841", "name": "4MZYMOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10789271", "map_id": "none", "name": "GGPS1 hexamer transfers IPPP to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10789265", "map_id": "none", "name": "holo-GGPS1 hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q12051", "map_id": "Q12051", "name": "BTS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL069C", "map_id": "YPL069C", "name": "BTS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775602", "map_id": "none", "name": "Autoglucosylation of GYG2 complexed with GYS2-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775597", "map_id": "none", "name": "GYG2:GYS2-b tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10775599", "map_id": "none", "name": "oligoGlc-GYG2:GYS2-b tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10775616", "map_id": "none", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775614", "map_id": "none", "name": "glycogen-GYG1:GYS1-b tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10785555", "map_id": "none", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_8851233", "map_id": "none", "name": "UTP,GTP,CTP,dTTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_2022884", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_8851224", "map_id": "none", "name": "UDP,GDP,CDP,dTDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_8851226", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10785549", "map_id": "none", "name": "NTPDase4:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10766160", "map_id": "none", "name": "ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10766157", "map_id": "Q08822", "name": "CIR2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "YOR356W", "map_id": "YOR356W", "name": "CIR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769932", "map_id": "none", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769929", "map_id": "none", "name": "PPAP2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10781083", "map_id": "none", "name": "ALDH3A2-1 oxidises HD2NAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10781080", "map_id": "none", "name": "ALDH3A2-1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10770608", "map_id": "none", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_159448", "map_id": "CHEBI:456215", "name": "AMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10770605", "map_id": "Q01574", "name": "ACS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10775516", "map_id": "none", "name": "GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775511", "map_id": "none", "name": "oligoGlc-GYG1:GYS1-a tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773288", "map_id": "none", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_110577", "map_id": "CHEBI:37563", "name": "CTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10773285", "map_id": "P38221", "name": "CDS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10763560", "map_id": "none", "name": "PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500172", "map_id": "none", "name": "Ino, dI", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:28997", "map_id": "CHEBI:28997", "name": "CHEBI:28997", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789066", "map_id": "none", "name": "IMPDH tetramers binds IMPDH inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9678719", "map_id": "none", "name": "IMPDH inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773306", "map_id": "none", "name": "PC is hydrolyzed to PA and choline by PLD1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10773301", "map_id": "P36126", "name": "SPO14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10763387", "map_id": "none", "name": "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10763384", "map_id": "P38972", "name": "ADE6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YGR061C", "map_id": "YGR061C", "name": "ADE6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763132", "map_id": "none", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10763129", "map_id": "none", "name": "UCK1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10775579", "map_id": "none", "name": "GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10789268", "map_id": "none", "name": "GGPS1 hexamer transfers IPPP to GPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191385", "map_id": "CHEBI:17407", "name": "FAPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10779036", "map_id": "none", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5676631", "map_id": "CHEBI:15456", "name": "VLC3HA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5676634", "map_id": "CHEBI:50998", "name": "2,3-TE-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10779031", "map_id": "P40857", "name": "PHS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YJL097W", "map_id": "YJL097W", "name": "PHS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10788222", "map_id": "none", "name": "PXLP-K56-SRR dimer isomerises L-Ser to D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10764143", "map_id": "none", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764140", "map_id": "none", "name": "GPD1/GPD1L homodimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P41911", "map_id": "P41911", "name": "GPD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL059W", "map_id": "YOL059W", "name": "GPD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q00055", "map_id": "Q00055", "name": "GPD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL022W", "map_id": "YDL022W", "name": "GPD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763361", "map_id": "none", "name": "AICAR + 10-Formyl-THF => FAICAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10763112", "map_id": "none", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10763109", "map_id": "none", "name": "PRPS2 dimer, PRPS1L dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10762072", "map_id": "none", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762069", "map_id": "none", "name": "pyruvate kinase tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10775607", "map_id": "none", "name": "Autoglucosylation of GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775604", "map_id": "none", "name": "GYG1:GYS1-a tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10785160", "map_id": "none", "name": "ALDH1A1 oxidises GA to DGA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6799497", "map_id": "CHEBI:32398", "name": "DGA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773606", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10773603", "map_id": "none", "name": "PI4KA/2A/2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P37297", "map_id": "P37297", "name": "STT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR305C", "map_id": "YLR305C", "name": "STT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P42951", "map_id": "P42951", "name": "LSB6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10776478", "map_id": "none", "name": "HLCS biotinylates ACACB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10776476", "map_id": "none", "name": "ACACB:2Mn2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10767433", "map_id": "none", "name": "Btn-ACACB:2Mn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10767652", "map_id": "none", "name": "depalmitoylated eNOS translocates from plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10767650", "map_id": "none", "name": "myristoylated eNOS dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10767486", "map_id": "none", "name": "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10773135", "map_id": "none", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2[4]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10773132", "map_id": "none", "name": "PLA2(4)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10769054", "map_id": "none", "name": "HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "reaction_10767494", "map_id": "none", "name": "Cytosolic folate export across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_197965", "map_id": "CHEBI:27470", "name": "FOLA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_200716", "map_id": "CHEBI:27470", "name": "FOLA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10767491", "map_id": "P46996", "name": "SLC46A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YJL163C", "map_id": "YJL163C", "name": "SLC46A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768943", "map_id": "none", "name": "phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389537", "map_id": "CHEBI:16810", "name": "2OG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389615", "map_id": "CHEBI:15538", "name": "Phytanoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389583", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389536", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10768940", "map_id": "none", "name": "PHYH:Fe++", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "P47181", "map_id": "P47181", "name": "PHYH(1-338)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR154W", "map_id": "YJR154W", "name": "PHYH(1-338)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10788342", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9023708", "map_id": "CHEBI:138563", "name": "5S,6S-epoxy-18(R)-HEPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9023712", "map_id": "CHEBI:81559", "name": "18(R)-RvE1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10763152", "map_id": "none", "name": "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500829", "map_id": "none", "name": "Cyt-Rib, dC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:15698", "map_id": "CHEBI:15698", "name": "CHEBI:15698", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500430", "map_id": "none", "name": "(d)Ura", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:16450", "map_id": "CHEBI:16450", "name": "CHEBI:16450", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10763149", "map_id": "none", "name": "CDA tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10772970", "map_id": "none", "name": "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10786551", "map_id": "none", "name": "NMRK1 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8869365", "map_id": "CHEBI:58527", "name": "NAR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10786548", "map_id": "P53915", "name": "NRK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10773475", "map_id": "none", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10781631", "map_id": "none", "name": "ALDH1B1 tetramer oxidises CH3CHO to CH3COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10781628", "map_id": "none", "name": "ALDH1B1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10770185", "map_id": "none", "name": "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10770182", "map_id": "none", "name": "ACSL3,4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10767476", "map_id": "none", "name": "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764049", "map_id": "none", "name": "Homologues of Btn-ACACA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10782610", "map_id": "none", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10782600", "map_id": "none", "name": "DHs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P32473", "map_id": "P32473", "name": "PDB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR221C", "map_id": "YBR221C", "name": "PDB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P16387", "map_id": "P16387", "name": "PDA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER178W", "map_id": "YER178W", "name": "PDA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P12695", "map_id": "P12695", "name": "LAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL071W", "map_id": "YNL071W", "name": "LAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10782602", "map_id": "none", "name": "lipoylated DHs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10781285", "map_id": "P39726", "name": "GCV3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10782607", "map_id": "P47051", "name": "AIM22", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "YJL046W", "map_id": "YJL046W", "name": "AIM22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10762216", "map_id": "none", "name": "D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10762213", "map_id": "none", "name": "PFKFB dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q12471", "map_id": "Q12471", "name": "PFK27", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL136C", "map_id": "YOL136C", "name": "PFK27", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06137", "map_id": "Q06137", "name": "PFKFB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR345W", "map_id": "YLR345W", "name": "PFKFB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773173", "map_id": "none", "name": "PG is hydrolyzed to 2-acyl LPG by PLA2[14]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10773170", "map_id": "none", "name": "PLA2(14)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10785552", "map_id": "none", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_8851227", "map_id": "none", "name": "UMP,GMP,CMP,dTMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10765673", "map_id": "none", "name": "Transcriptional activation of Acetyl-CoA carboxylase by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10765671", "map_id": "none", "name": "ACC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10784150", "map_id": "none", "name": "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10769083", "map_id": "none", "name": "Peroxisomal uptake of very long-chain fatty acyl CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_390394", "map_id": "CHEBI:52966", "name": "C26:0 CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_390260", "map_id": "CHEBI:52966", "name": "C26:0 CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10768823", "map_id": "none", "name": "ABCD1 homodimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10766760", "map_id": "none", "name": "Two FPP molecules dimerize to form presqualene diphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10781904", "map_id": "none", "name": "PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6784241", "map_id": "CHEBI:27391", "name": "1-pyrroline-3-hydroxy-5-carboxylate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10781901", "map_id": "none", "name": "PRODH2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P09368", "map_id": "P09368", "name": "PUT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10763162", "map_id": "none", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10763159", "map_id": "none", "name": "CTPS tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10786543", "map_id": "none", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10786540", "map_id": "Q12204", "name": "PITPNM3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10767496", "map_id": "none", "name": "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10777429", "map_id": "none", "name": "ARV1 transports CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10777426", "map_id": "Q06541", "name": "ARV1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YLR242C", "map_id": "YLR242C", "name": "ARV1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767533", "map_id": "none", "name": "SLC46A1 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10781613", "map_id": "none", "name": "AGK:Mg2+ phosphorylates MAG, DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_5696069", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5696066", "map_id": "none", "name": "MAG,DAG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "species_5696026", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5696037", "map_id": "none", "name": "LPA,PA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "species_417891", "map_id": "CHEBI:52288", "name": "LPA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10781610", "map_id": "none", "name": "AGK:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10788346", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024781", "map_id": "CHEBI:138647", "name": "4S(5)-epoxy-17(S)-HDHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024809", "map_id": "none", "name": "RvD3, RvD4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:138649", "map_id": "CHEBI:138649", "name": "CHEBI:138649", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:138648", "map_id": "CHEBI:138648", "name": "CHEBI:138648", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781648", "map_id": "none", "name": "MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10784754", "map_id": "none", "name": "MTMR12 binds MTM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10781641", "map_id": "none", "name": "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5696449", "map_id": "CHEBI:17408", "name": "MAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_6782195", "map_id": "CHEBI:17984", "name": "Acyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10789150", "map_id": "none", "name": "SPHK2 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769846", "map_id": "none", "name": "Homologues of SPHK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10789148", "map_id": "none", "name": "SPHK2:SPHK2 inhibitors", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "LigandDisplayForward?ligandId=6625", "map_id": "LigandDisplayForward?ligandId=6625", "name": "LigandDisplayForward?ligandId=6625", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=10641", "map_id": "LigandDisplayForward?ligandId=10641", "name": "LigandDisplayForward?ligandId=10641", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=10219", "map_id": "LigandDisplayForward?ligandId=10219", "name": "LigandDisplayForward?ligandId=10219", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=6624", "map_id": "LigandDisplayForward?ligandId=6624", "name": "LigandDisplayForward?ligandId=6624", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781989", "map_id": "none", "name": "DECR2 reduces LCtE-CoA to t3enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_113602", "map_id": "CHEBI:16474", "name": "NADPH", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_6786723", "map_id": "CHEBI:83727", "name": "LCtE-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389556", "map_id": "CHEBI:18009", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6786715", "map_id": "CHEBI:27700", "name": "t3enoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10781986", "map_id": "P32573", "name": "SPS19", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "false" }, { "id": "YNL202W", "map_id": "YNL202W", "name": "SPS19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773159", "map_id": "none", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10767517", "map_id": "none", "name": "SLC25A32 transports THF from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10767514", "map_id": "P40464", "name": "FLX1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YIL134W", "map_id": "YIL134W", "name": "FLX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768215", "map_id": "none", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_265283", "map_id": "CHEBI:15554", "name": "PGH2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_265287", "map_id": "CHEBI:15551", "name": "PGE2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10768212", "map_id": "P28707", "name": "SBA1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YKL117W", "map_id": "YKL117W", "name": "SBA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10774833", "map_id": "none", "name": "HLCS biotinylates PC:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10774820", "map_id": "none", "name": "4x(PC:Mn2+)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10781981", "map_id": "none", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1602447", "map_id": "CHEBI:16975", "name": "1-acyl LPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1602366", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10781978", "map_id": "none", "name": "DDHD1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773485", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10773482", "map_id": "none", "name": "PI4KA/2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10786556", "map_id": "none", "name": "NMRK2 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10761919", "map_id": "none", "name": "lipo-PDH decarboxylates PYR to Ac-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10761916", "map_id": "none", "name": "lipo-PDH", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10762130", "map_id": "none", "name": "ethanol + NAD+ => acetaldehyde + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30203", "map_id": "CHEBI:16236", "name": "EtOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10762127", "map_id": "none", "name": "alcohol dehydrogenase complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10773425", "map_id": "none", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10773535", "map_id": "none", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "reaction_10773153", "map_id": "none", "name": "DLCL is acylated to MLCL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1524080", "map_id": "CHEBI:60431", "name": "DLCL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10767135", "map_id": "none", "name": "IDO1 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767132", "map_id": "none", "name": "IDO1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10769042", "map_id": "none", "name": "trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "reaction_10773514", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10766591", "map_id": "none", "name": "FECH binds Fe2+ to PRIN9 to form heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_189487", "map_id": "CHEBI:15430", "name": "PRIN9", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10766588", "map_id": "none", "name": "2x(FECH:2Fe-2S cluster)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P16622", "map_id": "P16622", "name": "HEM15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR176W", "map_id": "YOR176W", "name": "HEM15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_391232", "map_id": "CHEBI:27889", "name": "Pb2+", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10766702", "map_id": "none", "name": "FDPS dimer transfers IPPP to GPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10786562", "map_id": "none", "name": "NMRK1 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10766720", "map_id": "none", "name": "HMGCR dimer reduces bHMG-CoA to MVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10766717", "map_id": "none", "name": "HMGCR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P12683", "map_id": "P12683", "name": "HMG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML075C", "map_id": "YML075C", "name": "HMG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767740", "map_id": "none", "name": "eNOS translocation from Golgi to Caveolae", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "reaction_10772965", "map_id": "none", "name": "2-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "reaction_10769833", "map_id": "none", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428126", "map_id": "CHEBI:31488", "name": "DHCE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10769830", "map_id": "none", "name": "LASS proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P38703", "map_id": "P38703", "name": "LAG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHL003C", "map_id": "YHL003C", "name": "LAG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P28496", "map_id": "P28496", "name": "LAC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL008C", "map_id": "YKL008C", "name": "LAC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10787624", "map_id": "none", "name": "MECR dimer reduces tdec2-CoA to DEC-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_77343", "map_id": "CHEBI:10723", "name": "tdec2-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_77308", "map_id": "CHEBI:28493", "name": "DEC-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10787621", "map_id": "none", "name": "MECR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P38071", "map_id": "P38071", "name": "ETR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR026C", "map_id": "YBR026C", "name": "ETR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786524", "map_id": "none", "name": "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10786521", "map_id": "none", "name": "OSBPL5,8,10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38755", "map_id": "P38755", "name": "OSH7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR001W", "map_id": "YHR001W", "name": "OSH7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P35843", "map_id": "P35843", "name": "HES1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR237W", "map_id": "YOR237W", "name": "HES1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769008", "map_id": "none", "name": "glyoxylate + NADPH + H+ => glycolate + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_10769005", "map_id": "Q02961", "name": "GRHPR", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "YPL113C", "map_id": "YPL113C", "name": "GRHPR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785535", "map_id": "none", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8936166", "map_id": "none", "name": "ATP,GTP,CTP,ITP,UTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_8851092", "map_id": "none", "name": "ADP,GDP,CDP,IDP,UDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10786911", "map_id": "none", "name": "Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10769786", "map_id": "none", "name": "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428182", "map_id": "CHEBI:17862", "name": "3-ketosphinganine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10769783", "map_id": "P38342", "name": "TSC10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YBR265W", "map_id": "YBR265W", "name": "TSC10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785504", "map_id": "none", "name": "NTPDase1 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10761841", "map_id": "none", "name": "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10761838", "map_id": "P38858", "name": "SOL3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YHR163W", "map_id": "YHR163W", "name": "SOL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10776243", "map_id": "none", "name": "PPP1R3C binds to glycogen:GYG2:GYS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10778265", "map_id": "none", "name": "DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778250", "map_id": "none", "name": "Me2K80-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10778263", "map_id": "none", "name": "Me3K80-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10778255", "map_id": "Q04089", "name": "DOT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YDR440W", "map_id": "YDR440W", "name": "DOT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775068", "map_id": "none", "name": "CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775059", "map_id": "none", "name": "CCND1:CDK4:PRMT5:WDR77", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P38274", "map_id": "P38274", "name": "HSL7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR133C", "map_id": "YBR133C", "name": "HSL7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10775065", "map_id": "none", "name": "CCND1:CDK4:PRMT5:pT5-WDR77", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778269", "map_id": "none", "name": "DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778245", "map_id": "none", "name": "MeK80-histone H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10776189", "map_id": "none", "name": "HDAC3 containing complexes deacetylate histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776109", "map_id": "none", "name": "Acetylated core histone octamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_5566518", "map_id": "CHEBI:30089", "name": "acetate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10776115", "map_id": "none", "name": "Core histone octamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776186", "map_id": "none", "name": "HDAC3-containing complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "CHEBI:57627", "map_id": "CHEBI:57627", "name": "CHEBI:57627", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53096", "map_id": "P53096", "name": "HOS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL194C", "map_id": "YGL194C", "name": "HOS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38262", "map_id": "P38262", "name": "SIF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR103W", "map_id": "YBR103W", "name": "SIF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25357", "map_id": "P25357", "name": "SNT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCR033W", "map_id": "YCR033W", "name": "SNT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10777324", "map_id": "none", "name": "RBBP7 binds histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775913", "map_id": "none", "name": "Homologues of RBBP7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10777322", "map_id": "none", "name": "RBBP7:Replicative histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10777305", "map_id": "none", "name": "Me2sR3-histone H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778200", "map_id": "none", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778197", "map_id": "none", "name": "WHSC1L1, Core MLL complex, SMYD3, SETD3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P38827", "map_id": "P38827", "name": "SET1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR119W", "map_id": "YHR119W", "name": "SET1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P43132", "map_id": "P43132", "name": "BRE2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR015W", "map_id": "YLR015W", "name": "BRE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36124", "map_id": "P36124", "name": "SET3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR029C", "map_id": "YKR029C", "name": "SET3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12529", "map_id": "Q12529", "name": "SET6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL165C", "map_id": "YPL165C", "name": "SET6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39706", "map_id": "P39706", "name": "SWD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAR003W", "map_id": "YAR003W", "name": "SWD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12504", "map_id": "Q12504", "name": "RKM4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR257C", "map_id": "YDR257C", "name": "RKM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38222", "map_id": "P38222", "name": "RKM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR030W", "map_id": "YBR030W", "name": "RKM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38123", "map_id": "P38123", "name": "SWD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR175W", "map_id": "YBR175W", "name": "SWD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10777042", "map_id": "none", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10777039", "map_id": "P02309", "name": "HHF2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10777010", "map_id": "none", "name": "SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10777007", "map_id": "none", "name": "SETD3, SETD7, WHSC1L1, Core MLL complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10777320", "map_id": "none", "name": "WDR5 binds Me2sR3-replicative histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776991", "map_id": "P38123", "name": "SWD3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10777318", "map_id": "none", "name": "WDR5:Me2sR3-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10777047", "map_id": "none", "name": "CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775241", "map_id": "none", "name": "MeR9-histone H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10777045", "map_id": "none", "name": "SWI/SNF chromatin remodelling complex:PRMT5:pT5-WDR77", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q06488", "map_id": "Q06488", "name": "RSC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR357W", "map_id": "YLR357W", "name": "RSC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P43609", "map_id": "P43609", "name": "RSC8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFR037C", "map_id": "YFR037C", "name": "RSC8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22082", "map_id": "P22082", "name": "SNF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR290C", "map_id": "YOR290C", "name": "SNF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P80428", "map_id": "P80428", "name": "ARP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL081C", "map_id": "YJL081C", "name": "ARP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32597", "map_id": "P32597", "name": "STH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL126W", "map_id": "YIL126W", "name": "STH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25632", "map_id": "P25632", "name": "RSC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCR052W", "map_id": "YCR052W", "name": "RSC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12406", "map_id": "Q12406", "name": "ARP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR034W", "map_id": "YPR034W", "name": "ARP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53628", "map_id": "P53628", "name": "SNF12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNR023W", "map_id": "YNR023W", "name": "SNF12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05123", "map_id": "Q05123", "name": "ARP9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR033W", "map_id": "YMR033W", "name": "ARP9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06168", "map_id": "Q06168", "name": "SFH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR321C", "map_id": "YLR321C", "name": "SFH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32591", "map_id": "P32591", "name": "SWI3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL176C", "map_id": "YJL176C", "name": "SWI3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10778587", "map_id": "none", "name": "CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778585", "map_id": "none", "name": "Me2sR9-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10776165", "map_id": "none", "name": "HDAC1:2-containing complex deacetylate histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776160", "map_id": "none", "name": "Sin3A complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P09547", "map_id": "P09547", "name": "SWI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL016W", "map_id": "YPL016W", "name": "SWI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03124", "map_id": "Q03124", "name": "RSC9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML127W", "map_id": "YML127W", "name": "RSC9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40505", "map_id": "P40505", "name": "SDS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL084C", "map_id": "YIL084C", "name": "SDS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P31385", "map_id": "P31385", "name": "DEP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL013W", "map_id": "YAL013W", "name": "DEP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38429", "map_id": "P38429", "name": "SAP30", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR263W", "map_id": "YMR263W", "name": "SAP30", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776163", "map_id": "none", "name": "HDAC1:2-containing complex:HDAC2 inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "LigandDisplayForward?ligandId=7489", "map_id": "LigandDisplayForward?ligandId=7489", "name": "LigandDisplayForward?ligandId=7489", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7009", "map_id": "LigandDisplayForward?ligandId=7009", "name": "LigandDisplayForward?ligandId=7009", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7006", "map_id": "LigandDisplayForward?ligandId=7006", "name": "LigandDisplayForward?ligandId=7006", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=6852", "map_id": "LigandDisplayForward?ligandId=6852", "name": "LigandDisplayForward?ligandId=6852", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7496", "map_id": "LigandDisplayForward?ligandId=7496", "name": "LigandDisplayForward?ligandId=7496", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10777211", "map_id": "none", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10777175", "map_id": "none", "name": "MeR12-histone H2A, Histone H2A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10777209", "map_id": "none", "name": "Me2aR12-histone H2A, MeR12-histone H2A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778258", "map_id": "none", "name": "DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10778598", "map_id": "none", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778596", "map_id": "P02309", "name": "HHF2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10778237", "map_id": "none", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776872", "map_id": "none", "name": "WHSC1, NSD1, SMYD2, ASH1L", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P38890", "map_id": "P38890", "name": "SET5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR207C", "map_id": "YHR207C", "name": "SET5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10776851", "map_id": "none", "name": "SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776848", "map_id": "P38827", "name": "SET1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10778273", "map_id": "none", "name": "WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10776875", "map_id": "none", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10777413", "map_id": "none", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10777410", "map_id": "none", "name": "Core MLL complex, SMYD3, PRDM9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10777134", "map_id": "none", "name": "Me2aR3-histone H3, MeR3-histone H3", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10789077", "map_id": "none", "name": "HDAC1:2-containing complex binds HDAC2 Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_9679795", "map_id": "none", "name": "HDAC2 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778240", "map_id": "none", "name": "WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10778267", "map_id": "none", "name": "WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10776286", "map_id": "none", "name": "HDAC10 deacetylates histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776283", "map_id": "P53973", "name": "HDA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10778195", "map_id": "none", "name": "MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778184", "map_id": "none", "name": "Histone H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10778188", "map_id": "none", "name": "MeK10-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10778190", "map_id": "P07248", "name": "ADR1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10782722", "map_id": "none", "name": "LRPP4(LRPP1-3,5) hydrolyse LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10782719", "map_id": "none", "name": "Homologues of LPPR4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10769347", "map_id": "none", "name": "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10769184", "map_id": "none", "name": "G-protein alpha (12/13):GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10769344", "map_id": "none", "name": "G-protein alpha (12/13):GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10769393", "map_id": "none", "name": "GEFs activate RhoA,B,C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769303", "map_id": "none", "name": "RhoA,B,C:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10769390", "map_id": "none", "name": "GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10769338", "map_id": "none", "name": "cAMP degradation by Phosphodiesterases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769330", "map_id": "P06776", "name": "PDE2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10770069", "map_id": "none", "name": "DCP1-DCP2 complex decaps mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770038", "map_id": "none", "name": "Deadenylated mRNA:Lsm1-7 Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P25644", "map_id": "P25644", "name": "PAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCR077C", "map_id": "YCR077C", "name": "PAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40070", "map_id": "P40070", "name": "LSM4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER112W", "map_id": "YER112W", "name": "LSM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P57743", "map_id": "P57743", "name": "LSM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR438C-A", "map_id": "YLR438C-A", "name": "LSM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53905", "map_id": "P53905", "name": "LSM7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL147W", "map_id": "YNL147W", "name": "LSM7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40089", "map_id": "P40089", "name": "LSM5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER146W", "map_id": "YER146W", "name": "LSM5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47017", "map_id": "P47017", "name": "LSM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL124C", "map_id": "YJL124C", "name": "LSM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06406", "map_id": "Q06406", "name": "LSM6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR378C", "map_id": "YDR378C", "name": "LSM6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38203", "map_id": "P38203", "name": "LSM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL026W", "map_id": "YBL026W", "name": "LSM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_430004", "map_id": "CHEBI:20794", "name": "7-MeGDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10770040", "map_id": "none", "name": "Decapped mRNA:LSM1-7 Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10770066", "map_id": "none", "name": "DCP1-DCP2 Decapping Complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P39517", "map_id": "P39517", "name": "DHH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL160C", "map_id": "YDL160C", "name": "DHH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53550", "map_id": "P53550", "name": "DCP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL118C", "map_id": "YNL118C", "name": "DCP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39998", "map_id": "P39998", "name": "EDC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YEL015W", "map_id": "YEL015W", "name": "EDC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12517", "map_id": "Q12517", "name": "DCP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL149W", "map_id": "YOL149W", "name": "DCP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770142", "map_id": "none", "name": "Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_429974", "map_id": "none", "name": "mature mRNA (eukaryotic, capped and deadenylated)", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_429926", "map_id": "none", "name": "capped oligoribonucleotide", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10770139", "map_id": "none", "name": "Exosome:SKI complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P35207", "map_id": "P35207", "name": "SKI2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SKI2", "map_id": "SKI2", "name": "SKI2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08162", "map_id": "Q08162", "name": "DIS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "DIS3", "map_id": "DIS3", "name": "DIS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P17883", "map_id": "P17883", "name": "SKI3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SKI3", "map_id": "SKI3", "name": "SKI3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770077", "map_id": "none", "name": "DCPS scavenges the 7-methylguanosine cap of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_429925", "map_id": "none", "name": "oligoribonucleotide with a 5'-diphosphate", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_430042", "map_id": "CHEBI:17825", "name": "7MGMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10770074", "map_id": "Q06151", "name": "DCS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YLR270W", "map_id": "YLR270W", "name": "DCS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770079", "map_id": "none", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770036", "map_id": "none", "name": "Lsm1-7 Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10771594", "map_id": "none", "name": "SLC46A1 transports hemes from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9707310", "map_id": "none", "name": "Hemes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_9707308", "map_id": "none", "name": "Hemes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10769319", "map_id": "none", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10769310", "map_id": "P38929", "name": "PMC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YGL006W", "map_id": "YGL006W", "name": "PMC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10777836", "map_id": "none", "name": "KCNK dimers transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10777833", "map_id": "none", "name": "KCNK dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10777914", "map_id": "none", "name": "ATP2B4 binds to NOS1, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10769316", "map_id": "P38929", "name": "PMC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10777912", "map_id": "none", "name": "ATP2B4:NOS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P38929", "map_id": "P38929", "name": "PMC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789363", "map_id": "none", "name": "MCM3 binds MCM5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760361", "map_id": "none", "name": "MCM3:MCM5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10789309", "map_id": "none", "name": "ORC1 binds to H4K20me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10789305", "map_id": "none", "name": "H4K20Me2-nucleosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10760200", "map_id": "P54784", "name": "ORC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10789307", "map_id": "none", "name": "ORC1:H4K20Me2-nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10789288", "map_id": "none", "name": "ORC1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10789286", "map_id": "P54784", "name": "ORC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10789367", "map_id": "none", "name": "MCM2 binds MCM4:MCM6:MCM7 heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760351", "map_id": "none", "name": "MCM2:MCM4:MCM6:MCM7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10760180", "map_id": "none", "name": "ORC2 binds ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760176", "map_id": "P54790", "name": "ORC3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760172", "map_id": "P32833", "name": "ORC2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760178", "map_id": "none", "name": "ORC2:ORC3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10760188", "map_id": "none", "name": "ORC5 binds ORC2:ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760184", "map_id": "P50874", "name": "ORC5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760186", "map_id": "none", "name": "ORC2:ORC3:ORC5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10760196", "map_id": "none", "name": "Formation of ORC(2-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760192", "map_id": "P54791", "name": "ORC4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760194", "map_id": "none", "name": "ORC(2-5)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10760222", "map_id": "none", "name": "CDC6 association with ORC(1-6) at replication origins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760218", "map_id": "none", "name": "ORC(1-6):origin of replication", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10760220", "map_id": "none", "name": "ORC(1-6):CDC6:origin of replication", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10789311", "map_id": "none", "name": "Formation of MCM2-7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10789365", "map_id": "none", "name": "MCM4, MCM6 and MCM7 form a heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760343", "map_id": "P53091", "name": "MCM6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760347", "map_id": "P38132", "name": "MCM7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10760339", "map_id": "P30665", "name": "MCM4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10760210", "map_id": "none", "name": "Formation of ORC(1-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10760204", "map_id": "none", "name": "ORC1:origin of replication", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10760208", "map_id": "none", "name": "ORC(1-5):origin of replication", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10784856", "map_id": "none", "name": "ING2 binds PI5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10784854", "map_id": "none", "name": "ING2:PI5P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10786979", "map_id": "none", "name": "PIN1 binds phosphorylated PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10786972", "map_id": "none", "name": "p-S326-PIP4K2B dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10771753", "map_id": "P22696", "name": "ESS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10786977", "map_id": "none", "name": "p-S326-PIP4K2B dimers:PIN1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10786975", "map_id": "none", "name": "MAP2K6 phosphorylates PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10786961", "map_id": "none", "name": "PIP4K2B dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10770703", "map_id": "none", "name": "Homologues of p-S207,T211-MAP2K6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10764546", "map_id": "none", "name": "PDPK1 phosphorylates AKT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764531", "map_id": "none", "name": "AKT2:PIP3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10764543", "map_id": "none", "name": "p-T309,S474-AKT2:PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10764517", "map_id": "none", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10772818", "map_id": "none", "name": "Phosphorylation of USP8 by P-AKT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10772805", "map_id": "none", "name": "Homologues of USP8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10772816", "map_id": "none", "name": "Homologues of p-T945-USP8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10768224", "map_id": "none", "name": "NPC1L1 binds ezetimibe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_265479", "map_id": "LigandDisplayForward?ligandId=6816", "name": "ezetimibe", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10768220", "map_id": "Q12200", "name": "NCR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10768222", "map_id": "none", "name": "NPC1L1:ezetimibe", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10777748", "map_id": "none", "name": "ADH1A,1C,4 oxidise atROL to atRAL in vitro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_975599", "map_id": "CHEBI:17336", "name": "atROL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10777745", "map_id": "none", "name": "ADH1A,1C,4 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10777718", "map_id": "none", "name": "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10777715", "map_id": "none", "name": "RDH10,16,DHRS9,RDHE2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10777743", "map_id": "none", "name": "ALDHs oxidise atRAL to atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5334816", "map_id": "CHEBI:15367", "name": "atRA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10777740", "map_id": "none", "name": "ALDH1A1,2,3 tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10777778", "map_id": "none", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10777775", "map_id": "none", "name": "RDH11,14,DHRS3,DHRS4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P34251", "map_id": "P34251", "name": "RDH14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL181W", "map_id": "YNL181W", "name": "RDH14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08651", "map_id": "Q08651", "name": "ENV9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR246C", "map_id": "YOR246C", "name": "ENV9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53878", "map_id": "P53878", "name": "RDH14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10784158", "map_id": "none", "name": "PLK3 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10784153", "map_id": "P23748", "name": "phospho-MIH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10784155", "map_id": "P32562", "name": "CDC5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10766925", "map_id": "none", "name": "Dynamin is recruited to the gap junction plaque", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10766678", "map_id": "none", "name": "Dynamin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10766651", "map_id": "none", "name": "planar gap junction plaques associated with Dab2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10766680", "map_id": "none", "name": "Planar gap junction plaques associated with Dab2 and Dynamin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10788439", "map_id": "none", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10788429", "map_id": "none", "name": "PEX5S,L:Cargo:PEX13:PEX14:PEX2:PEX10:PEX12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "P32573", "map_id": "P32573", "name": "SPS19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32796", "map_id": "P32796", "name": "CAT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12524", "map_id": "Q12524", "name": "PCD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR151C", "map_id": "YLR151C", "name": "PCD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06010", "map_id": "Q06010", "name": "STE23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR389C", "map_id": "YLR389C", "name": "STE23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41903", "map_id": "P41903", "name": "TES1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788437", "map_id": "none", "name": "Cargo proteins containing PTS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "reaction_10788389", "map_id": "none", "name": "PEX7 binds cargo proteins containing PTS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788385", "map_id": "none", "name": "Cargo proteins containing PTS2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10788379", "map_id": "P39108", "name": "PEX7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YDR142C", "map_id": "YDR142C", "name": "PEX7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788387", "map_id": "none", "name": "PEX7:Cargo proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P39108", "map_id": "P39108", "name": "PEX7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10788486", "map_id": "none", "name": "PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10788445", "map_id": "none", "name": "PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "species_10788447", "map_id": "none", "name": "PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10788441", "map_id": "none", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10788427", "map_id": "none", "name": "PEX13:PEX14:PEX2:PEX10:PEX12", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "species_10788425", "map_id": "none", "name": "PEX5S,L:Cargo protein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788484", "map_id": "none", "name": "Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10788476", "map_id": "none", "name": "PEX5L:PEX7:Cargo:PEX13:PEX14:PEX2:PEX10:PEX12", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "species_10788482", "map_id": "none", "name": "Cargo proteins containing PTS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "reaction_10788452", "map_id": "none", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10788449", "map_id": "none", "name": "PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10766513", "map_id": "none", "name": "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_189246", "map_id": "none", "name": "Fru, Gal, Glc", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:17118", "map_id": "CHEBI:17118", "name": "CHEBI:17118", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_189219", "map_id": "none", "name": "Fru, Gal, Glc", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10766510", "map_id": "none", "name": "GLUT2 / SLC2A2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10766502", "map_id": "none", "name": "SLC2A5 transports fructose from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_189049", "map_id": "CHEBI:15824", "name": "Fru", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10766499", "map_id": "none", "name": "Homologues of SLC2A5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10782658", "map_id": "none", "name": "TORC2 complex phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10782648", "map_id": "none", "name": "Homologues of SGK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10782656", "map_id": "none", "name": "Homologues of p-S422-SGK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10782713", "map_id": "none", "name": "CCNK:CDK12 binds RNA Pol II at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10782693", "map_id": "none", "name": "Elongation Complex at DNA Repair Genes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10782677", "map_id": "none", "name": "CCNK:CDK12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10782695", "map_id": "none", "name": "CCNK:CDK12:Elongation Complex at DNA Repair Genes", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10784265", "map_id": "none", "name": "AKT phosphorylates KAT6A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10784263", "map_id": "none", "name": "p-T369-KAT6A:ING5:MEAF6:BRPF1,(2,3)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10767160", "map_id": "none", "name": "AKT phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767147", "map_id": "none", "name": "Homologues of MDM2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10767157", "map_id": "none", "name": "Homologues of p-S166,S188-MDM2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10782671", "map_id": "none", "name": "PDPK1 phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10782666", "map_id": "none", "name": "Homologues of p-T256,S422-SGK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10784830", "map_id": "none", "name": "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10784818", "map_id": "none", "name": "RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P53968", "map_id": "P53968", "name": "CRZ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL027W", "map_id": "YNL027W", "name": "CRZ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784827", "map_id": "none", "name": "RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10784216", "map_id": "none", "name": "MDM2 homodimers auto-ubiquitinate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10784206", "map_id": "none", "name": "p-S166,S188-MDM2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10784213", "map_id": "none", "name": "PolyUb,p-S166,S188-MDM2 homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10782642", "map_id": "none", "name": "MDM2 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10782679", "map_id": "none", "name": "CCNK binds CDK12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10782675", "map_id": "Q03957", "name": "CTK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10765011", "map_id": "Q05949", "name": "BUR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10784852", "map_id": "none", "name": "RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10784835", "map_id": "P40084", "name": "RTR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YER139C", "map_id": "YER139C", "name": "RTR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784846", "map_id": "Q05543", "name": "RTT103", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YDR289C", "map_id": "YDR289C", "name": "RTT103", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784844", "map_id": "none", "name": "RPRD1A,B:RPRD1A,B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q05543", "map_id": "Q05543", "name": "RTT103", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10784850", "map_id": "none", "name": "RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P40084", "map_id": "P40084", "name": "RTR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10765625", "map_id": "none", "name": "TFAM binds to mitochondrial promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_163305", "map_id": "none", "name": "mitochondrial DNA promoter", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10765621", "map_id": "none", "name": "Homologues of TFAM", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10765623", "map_id": "none", "name": "TFAM:mitochondrial promoter complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10782685", "map_id": "none", "name": "CCNK binds CDK13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10782681", "map_id": "Q03957", "name": "CTK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10782683", "map_id": "none", "name": "CCNK:CDK13", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10782673", "map_id": "none", "name": "MDM2 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10782640", "map_id": "none", "name": "(CDK1,CDK2):CCNA phosphorylates MDM2 at T218", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10782638", "map_id": "none", "name": "Homologues of p-S166,S188,T218-MDM2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10782669", "map_id": "none", "name": "SGK1 phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10784258", "map_id": "none", "name": "CK2 binds FACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10784254", "map_id": "none", "name": "Casein kinase II", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10784256", "map_id": "none", "name": "CK2:FACT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10782711", "map_id": "none", "name": "CDK12 phosphorylates RNA Pol II CTD at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10782708", "map_id": "none", "name": "CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10770856", "map_id": "none", "name": "PKCalpha phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10770833", "map_id": "Q04067", "name": "TIF35", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10770851", "map_id": "Q04067", "name": "phospho-TIF35", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10770853", "map_id": "P24583", "name": "PKC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10770848", "map_id": "none", "name": "PKCdelta phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10770843", "map_id": "Q04067", "name": "phospho-TIF35", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10770845", "map_id": "P24583", "name": "PKC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10771129", "map_id": "none", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_517622", "map_id": "none", "name": "mRNA Transcript Targeted by HuR Phosphorylated on Ser221 and Ser318", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10771127", "map_id": "none", "name": "HuR with phosphoserine221 and phosphoserine318:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10771125", "map_id": "none", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_450605", "map_id": "none", "name": "mRNA Transcript Targeted by HuR Phosphorylated on Ser158 and Ser318.", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10771123", "map_id": "none", "name": "HuR with phosphoserine221 and phosphoserine158:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10770837", "map_id": "none", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_450613", "map_id": "none", "name": "mRNA Transcript Targeted by HuR with Unknown Phosphorylation", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10770835", "map_id": "none", "name": "HuR with Unknown Phosphorylation: mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10776322", "map_id": "none", "name": "Initiation of SAHF formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776313", "map_id": "Q01448", "name": "HPC2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YBR215W", "map_id": "YBR215W", "name": "HPC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776308", "map_id": "P32479", "name": "HIR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YBL008W", "map_id": "YBL008W", "name": "HIR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776318", "map_id": "P47171", "name": "HIR3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YJR140C", "map_id": "YJR140C", "name": "HIR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776303", "map_id": "P32447", "name": "ASF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YJL115W", "map_id": "YJL115W", "name": "ASF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10776320", "map_id": "none", "name": "HIRA:ASF1A:UBN1:CABIN1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q01448", "map_id": "Q01448", "name": "HPC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32479", "map_id": "P32479", "name": "HIR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32447", "map_id": "P32447", "name": "ASF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47171", "map_id": "P47171", "name": "HIR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771087", "map_id": "none", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10771084", "map_id": "none", "name": "AQP0,1,2,3,4,5,7,8,9,10,11,12A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10771099", "map_id": "none", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_432019", "map_id": "CHEBI:16199", "name": "Urea", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10771096", "map_id": "none", "name": "AQP9,10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10770170", "map_id": "none", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_192438", "map_id": "CHEBI:17754", "name": "glycerol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10770167", "map_id": "none", "name": "AQP7 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10771101", "map_id": "none", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10771094", "map_id": "none", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10770159", "map_id": "none", "name": "Aquaporin-9 passively transports glycerol into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10770156", "map_id": "none", "name": "AQP9 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10771092", "map_id": "none", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10771090", "map_id": "none", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10772773", "map_id": "none", "name": "Activation of TRESK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10772770", "map_id": "none", "name": "TRESK homodimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10772786", "map_id": "none", "name": "Activation of TALK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10772783", "map_id": "none", "name": "TALK 1and 2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10772753", "map_id": "none", "name": "Activation of tandem pore domain in a weak inwardly rectifying K+ channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10772750", "map_id": "none", "name": "TWIK channels", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10772736", "map_id": "none", "name": "Activation of THIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10772733", "map_id": "none", "name": "THIK1 homodimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10787432", "map_id": "none", "name": "MAF1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10787425", "map_id": "P41910", "name": "MAF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YDR005C", "map_id": "YDR005C", "name": "MAF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787423", "map_id": "P41910", "name": "MAF1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10764398", "map_id": "none", "name": "Recognition of AAUAAA sequence by CPSF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10762363", "map_id": "none", "name": "CPSF", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q01329", "map_id": "Q01329", "name": "PTA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL043C", "map_id": "YAL043C", "name": "PTA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12102", "map_id": "Q12102", "name": "CFT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR115W", "map_id": "YLR115W", "name": "CFT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P45976", "map_id": "P45976", "name": "FIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR093C", "map_id": "YJR093C", "name": "FIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P42841", "map_id": "P42841", "name": "PFS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL317W", "map_id": "YNL317W", "name": "PFS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06224", "map_id": "Q06224", "name": "YSH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR277C", "map_id": "YLR277C", "name": "YSH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06102", "map_id": "Q06102", "name": "YTH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR107C", "map_id": "YPR107C", "name": "YTH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06632", "map_id": "Q06632", "name": "CFT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR301W", "map_id": "YDR301W", "name": "CFT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10764394", "map_id": "none", "name": "capped intronless pre-mRNA:CBC complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10764396", "map_id": "none", "name": "CPSF:capped intronless pre-mRNA:CBC complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10789005", "map_id": "none", "name": "ATM:PEX5 translocates from cytosol to peroxisomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788984", "map_id": "none", "name": "ATM:PEX5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10788990", "map_id": "none", "name": "ATM:PEX5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10788897", "map_id": "none", "name": "PolyUb-Misfolded Proteins:HDAC6 bind dynein motor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788876", "map_id": "none", "name": "PolyUb-Misfolded Proteins:HDAC6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10788893", "map_id": "none", "name": "Dynein complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P40960", "map_id": "P40960", "name": "PAC11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR488C", "map_id": "YDR488C", "name": "PAC11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788895", "map_id": "none", "name": "PolyUb-Misfolded Proteins:HDAC6:Dynein complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788915", "map_id": "none", "name": "Aggresome dissociates from dynein and microtubule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_18667", "compartment_display": "microtubule organizing center" }, { "id": "species_10788907", "map_id": "none", "name": "Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_18667", "compartment_display": "microtubule organizing center", "complex": "true" }, { "id": "species_10788913", "map_id": "none", "name": "Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10789014", "map_id": "none", "name": "ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10788999", "map_id": "none", "name": "ATM dimer:p-PEX5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "species_10789012", "map_id": "none", "name": "ATM dimer:Ub-p-PEX5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10788869", "map_id": "none", "name": "Ub:misfolded proteins polymerize to PolyUb:misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788867", "map_id": "none", "name": "PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10789001", "map_id": "none", "name": "ATM dimer:PEX5 phosphorylates PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10788992", "map_id": "none", "name": "ATM dimer:PEX5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10788986", "map_id": "none", "name": "ATM binds PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788982", "map_id": "P38110", "name": "TEL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10788423", "map_id": "P35056", "name": "PEX5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10789003", "map_id": "none", "name": "ATM:PEX5 binds ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10788988", "map_id": "P38110", "name": "TEL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_1250243", "map_id": "CHEBI:26523", "name": "ROS", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10763693", "map_id": "none", "name": "Endosome acidification", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17940", "compartment_display": "endosome" }, { "id": "species_74722", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171907", "compartment_display": "endosome lumen", "complex": "false" }, { "id": "species_10763690", "map_id": "none", "name": "V-ATPase:ATP6AP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10779165", "map_id": "none", "name": "MRN bound to shortened telomeres activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779160", "map_id": "none", "name": "Shortened telomere:MRN:Ac-K3016-ATM dimer:KAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779162", "map_id": "none", "name": "Shortened telomere:MRN:KAT5:p-S1981,Ac-K3016-ATM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10787738", "map_id": "none", "name": "KDM6B binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775179", "map_id": "P14922", "name": "CYC8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10775181", "map_id": "none", "name": "KDM6B:Fe2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P14922", "map_id": "P14922", "name": "CYC8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775231", "map_id": "none", "name": "Active p38 MAPK phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775221", "map_id": "none", "name": "phospho-p38 MAPK: MAPKAPK5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10775228", "map_id": "none", "name": "phospho-p38 MAPK:p-T-182-MAPKAPK5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10775223", "map_id": "none", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775219", "map_id": "none", "name": "p38 MAPK:MAPKAPK5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10782617", "map_id": "none", "name": "KAT5 acetylates ATM at shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10782614", "map_id": "none", "name": "Shortened telomere:MRN:ATM dimer:KAT5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10775192", "map_id": "none", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770760", "map_id": "none", "name": "MAP2K3,MAP2K6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10775189", "map_id": "P23561", "name": "STE11", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YLR362W", "map_id": "YLR362W", "name": "STE11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775184", "map_id": "none", "name": "KDM6B demethylates H3K27me3 on p16INK4A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775172", "map_id": "none", "name": "CDKN2A Gene:H3K27Me3-Nucleosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10775174", "map_id": "none", "name": "CDKN2A Gene:Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10771963", "map_id": "none", "name": "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_947588", "map_id": "none", "name": "APLs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_947587", "compartment_display": "cytoplasmic side of plasma membrane", "complex": "true" }, { "id": "species_947594", "map_id": "none", "name": "APLs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_947586", "compartment_display": "external side of plasma membrane", "complex": "true" }, { "id": "species_10771935", "map_id": "none", "name": "P-type ATPases type IV", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P40527", "map_id": "P40527", "name": "NEO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL048W", "map_id": "YIL048W", "name": "NEO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10777455", "map_id": "none", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5252122", "map_id": "CHEBI:60240", "name": "divalent metal cation", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_5252016", "map_id": "CHEBI:60240", "name": "divalent metal cation", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10777450", "map_id": "Q12697", "name": "YPK9", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YOR291W", "map_id": "YOR291W", "name": "YPK9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775325", "map_id": "none", "name": "TRPs transport extracellular Ca2+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775312", "map_id": "Q12324", "name": "YVC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YOR087W", "map_id": "YOR087W", "name": "YVC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781096", "map_id": "none", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29418", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1981162", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10781093", "map_id": "P39986", "name": "SPF1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YEL031W", "map_id": "YEL031W", "name": "SPF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771860", "map_id": "none", "name": "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_167012", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10771857", "map_id": "none", "name": "ATP2C1/2:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "P13586", "map_id": "P13586", "name": "PMR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL167C", "map_id": "YGL167C", "name": "PMR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771868", "map_id": "none", "name": "ATP7B transports cytosolic Cu2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_209799", "map_id": "CHEBI:29036", "name": "Cu2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_936901", "map_id": "CHEBI:29036", "name": "Cu2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10771865", "map_id": "P38995", "name": "CCC2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "YDR270W", "map_id": "YDR270W", "name": "CCC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10781101", "map_id": "none", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5692450", "map_id": "CHEBI:36916", "name": "cation", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5692484", "map_id": "CHEBI:36916", "name": "cation", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10781098", "map_id": "Q12697", "name": "YPK9", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10774664", "map_id": "none", "name": "ANOs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10774659", "map_id": "P38250", "name": "IST2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YBR086C", "map_id": "YBR086C", "name": "IST2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10789201", "map_id": "none", "name": "TRPV1 transports Ca2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10774674", "map_id": "none", "name": "CLCN4/5/6 exchange Cl- for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2731008", "map_id": "CHEBI:17996", "name": "Cl-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171907", "compartment_display": "endosome lumen", "complex": "false" }, { "id": "species_10774669", "map_id": "P37020", "name": "GEF1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "false" }, { "id": "YJR040W", "map_id": "YJR040W", "name": "GEF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768792", "map_id": "none", "name": "IRE1 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10768784", "map_id": "none", "name": "IRE1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P32361", "map_id": "P32361", "name": "phospho-IRE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "phospho-IRE1", "map_id": "phospho-IRE1", "name": "phospho-IRE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768789", "map_id": "none", "name": "p-S724-IRE1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10768794", "map_id": "none", "name": "IRE1 binds IRE1 forming dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10768782", "map_id": "P32361", "name": "IRE1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10770262", "map_id": "none", "name": "ZIP7 mediates zinc efflux from the endoplasmic reticulum", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_442320", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10770259", "map_id": "P40544", "name": "YKE4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "YIL023C", "map_id": "YIL023C", "name": "YKE4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10779105", "map_id": "none", "name": "MTMR14, MTMR3 dephosphorylate PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10773546", "map_id": "P47147", "name": "YMR1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10778999", "map_id": "none", "name": "ULK1 phosphorylates ATG13 and RB1CC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778709", "map_id": "none", "name": "p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P53104", "map_id": "P53104", "name": "ATG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06628", "map_id": "Q06628", "name": "ATG13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR185W", "map_id": "YPR185W", "name": "ATG13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12527", "map_id": "Q12527", "name": "ATG11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR049C", "map_id": "YPR049C", "name": "ATG11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10778996", "map_id": "none", "name": "p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10779119", "map_id": "none", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10779063", "map_id": "P38316", "name": "ATG12", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10779115", "map_id": "none", "name": "ATG7 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10779117", "map_id": "none", "name": "ATG12:ATG7 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10778714", "map_id": "none", "name": "p-AMPK:AMP binds the ULK complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778630", "map_id": "none", "name": "ULK1:ATG13:RB1CC1:ATG101", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10768748", "map_id": "none", "name": "p-AMPK heterotrimer:AMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10778632", "map_id": "none", "name": "p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788354", "map_id": "none", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10779327", "map_id": "none", "name": "ATG12:ATG7:CysO572-ATG7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10779133", "map_id": "none", "name": "ATG3 transfers LC3 from ATG7 to ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10779128", "map_id": "none", "name": "LC3:CysO572-ATG7:ATG7:ATG3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P40344", "map_id": "P40344", "name": "ATG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNR007C", "map_id": "YNR007C", "name": "ATG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10779130", "map_id": "none", "name": "LC3:CysO263-ATG3:ATG7 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10778727", "map_id": "none", "name": "Beclin-1 complex phosphorylates PtdIns", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10778724", "map_id": "none", "name": "ATG14:PIK3C3:PIK3R4:p-S15-BECN1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10778646", "map_id": "none", "name": "AMPK (complex) phosphorylates ULK1 (complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778643", "map_id": "none", "name": "p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10779026", "map_id": "none", "name": "WIPIs bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10779022", "map_id": "none", "name": "WIPI1,WIPI2,(WDR45,WDR45B)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q02887", "map_id": "Q02887", "name": "ATG21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL100W", "map_id": "YPL100W", "name": "ATG21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P43601", "map_id": "P43601", "name": "ATG18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFR021W", "map_id": "YFR021W", "name": "ATG18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P50079", "map_id": "P50079", "name": "HSV2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR223C", "map_id": "YGR223C", "name": "HSV2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5693050", "map_id": "CHEBI:17283", "name": "PI3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "false" }, { "id": "species_10779024", "map_id": "none", "name": "WIPI1,WIPI2,(WDR45,WDR45B):PI3P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "true" }, { "id": "reaction_10778712", "map_id": "none", "name": "Thr-180 of ULK1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10779077", "map_id": "none", "name": "ATG16L1 complex transfers LC3 from ATG3 to PE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5681998", "map_id": "CHEBI:16038", "name": "PE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "false" }, { "id": "species_10779055", "map_id": "none", "name": "CysO263-ATG3:LC3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10779059", "map_id": "P40344", "name": "ATG3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10779057", "map_id": "none", "name": "LC3:PE", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "true" }, { "id": "species_10779074", "map_id": "none", "name": "ATG16L1 complex:WIPI2:PI(3,5)P2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "true" }, { "id": "reaction_10779143", "map_id": "none", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10779126", "map_id": "none", "name": "LC3:CysO572-ATG7:ATG7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10779211", "map_id": "none", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane" }, { "id": "species_10779202", "map_id": "none", "name": "LC3:PE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane", "complex": "true" }, { "id": "species_10779209", "map_id": "none", "name": "UVRAG complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q05919", "map_id": "Q05919", "name": "VPS38", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR360W", "map_id": "YLR360W", "name": "VPS38", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10771366", "map_id": "none", "name": "ESCRT-III", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10779191", "map_id": "none", "name": "The phagophore extends from the PIP3-enriched structure", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10779182", "map_id": "none", "name": "ATG14:PIK3C3:PIK3R4:p-S15-BECN1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "true" }, { "id": "species_10779187", "map_id": "Q12142", "name": "ATG9", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "false" }, { "id": "YDL149W", "map_id": "YDL149W", "name": "ATG9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10779329", "map_id": "none", "name": "LC3:ATG7 dimer binds ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10779107", "map_id": "none", "name": "ULK complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10779099", "map_id": "none", "name": "p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10779420", "map_id": "none", "name": "ULK1 is dephosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10779418", "map_id": "none", "name": "p-S758-ULK1:ATG13:RB1CC1:ATG101", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10779102", "map_id": "none", "name": "ULK1 phosphorylates Beclin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10779087", "map_id": "none", "name": "Beclin-1 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10779387", "map_id": "none", "name": "ATG7:ATG3:LC3 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10779113", "map_id": "none", "name": "Beclin-1 complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10779111", "map_id": "none", "name": "BECN1 complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10769778", "map_id": "none", "name": "Proton-coupled histidine and di-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_427984", "map_id": "none", "name": "Histidine/di-peptides", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "CHEBI:90799", "map_id": "CHEBI:90799", "name": "CHEBI:90799", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:32513", "map_id": "CHEBI:32513", "name": "CHEBI:32513", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_428040", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_428003", "map_id": "none", "name": "Histidine/di-peptides", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:46761", "map_id": "CHEBI:46761", "name": "CHEBI:46761", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10769773", "map_id": "P32901", "name": "PTR2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "reaction_10787736", "map_id": "none", "name": "SLC30A10 transports Mn2+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_266099", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10787733", "map_id": "none", "name": "Homologues of SLC30A10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P20107", "map_id": "P20107", "name": "ZRC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR243C", "map_id": "YMR243C", "name": "ZRC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32798", "map_id": "P32798", "name": "COT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR316C", "map_id": "YOR316C", "name": "COT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770232", "map_id": "none", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_437295", "map_id": "CHEBI:29036", "name": "Cu2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10770229", "map_id": "P38865", "name": "CTR2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YHR175W", "map_id": "YHR175W", "name": "CTR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770216", "map_id": "none", "name": "ZnT1 mediates the efflux of zinc from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10770213", "map_id": "P20107", "name": "ZRC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10770208", "map_id": "none", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_446589", "map_id": "none", "name": "MATE substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:8428", "map_id": "CHEBI:8428", "name": "CHEBI:8428", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:46020", "map_id": "CHEBI:46020", "name": "CHEBI:46020", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:42820", "map_id": "CHEBI:42820", "name": "CHEBI:42820", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16737", "map_id": "CHEBI:16737", "name": "CHEBI:16737", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=1231", "map_id": "LigandDisplayForward?ligandId=1231", "name": "LigandDisplayForward?ligandId=1231", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:641", "map_id": "CHEBI:641", "name": "CHEBI:641", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:6801", "map_id": "CHEBI:6801", "name": "CHEBI:6801", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_446597", "map_id": "none", "name": "MATE substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10770205", "map_id": "none", "name": "MATE1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P38767", "map_id": "P38767", "name": "ERC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR032W", "map_id": "YHR032W", "name": "ERC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05497", "map_id": "Q05497", "name": "SLC47A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR338C", "map_id": "YDR338C", "name": "SLC47A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769984", "map_id": "none", "name": "HMIT co-transports myo-inositol with a proton", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429130", "map_id": "CHEBI:17268", "name": "Ins", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10769981", "map_id": "P30605", "name": "ITR1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YDR497C", "map_id": "YDR497C", "name": "ITR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769870", "map_id": "none", "name": "Vesicular inhibitory amino acid transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_201753", "compartment_display": "synaptic vesicle membrane" }, { "id": "species_428548", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20600", "compartment_display": "synaptic vesicle", "complex": "false" }, { "id": "species_428592", "map_id": "none", "name": "Inhibitory amino acids", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_916850", "map_id": "CHEBI:59888", "name": "GABA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_428632", "map_id": "none", "name": "Inhibitory amino acids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20600", "compartment_display": "synaptic vesicle", "complex": "true" }, { "id": "species_10769867", "map_id": "P47082", "name": "AVT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_201753", "compartment_display": "synaptic vesicle membrane", "complex": "false" }, { "id": "YJR001W", "map_id": "YJR001W", "name": "AVT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785998", "map_id": "none", "name": "SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10785995", "map_id": "P38921", "name": "PET8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YNL003C", "map_id": "YNL003C", "name": "PET8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768477", "map_id": "none", "name": "SLC16A10-mediated uptake of aromatic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_352161", "map_id": "none", "name": "ligands of SLC16A10", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:58315", "map_id": "CHEBI:58315", "name": "CHEBI:58315", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_352139", "map_id": "none", "name": "ligands of SLC16A10", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10768474", "map_id": "none", "name": "Homologues of SLC16A10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P25568", "map_id": "P25568", "name": "ATG22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCL038C", "map_id": "YCL038C", "name": "ATG22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53918", "map_id": "P53918", "name": "ESBP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL125C", "map_id": "YNL125C", "name": "ESBP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08777", "map_id": "Q08777", "name": "MCH5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR306C", "map_id": "YOR306C", "name": "MCH5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08268", "map_id": "Q08268", "name": "MCH4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL119C", "map_id": "YOL119C", "name": "MCH4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36032", "map_id": "P36032", "name": "MCH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL221W", "map_id": "YKL221W", "name": "MCH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10778165", "map_id": "none", "name": "SLC26A4 transports I- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_209785", "map_id": "CHEBI:16382", "name": "I-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_209818", "map_id": "CHEBI:16382", "name": "I-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10778162", "map_id": "P53394", "name": "SLC26A4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10768673", "map_id": "none", "name": "SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_29588", "map_id": "CHEBI:57427", "name": "L-Leu", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_379430", "map_id": "none", "name": "L-Arg, CySS-, L-Lys", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_379444", "map_id": "CHEBI:16283", "name": "CySS-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_379440", "map_id": "none", "name": "L-Arg, CySS-, L-Lys", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10768670", "map_id": "none", "name": "SLC7A9:SLC3A1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P53341", "map_id": "P53341", "name": "MAL12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR292W", "map_id": "YGR292W", "name": "MAL12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53051", "map_id": "P53051", "name": "IMA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR287C", "map_id": "YGR287C", "name": "IMA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P50276", "map_id": "P50276", "name": "MUP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR055W", "map_id": "YGR055W", "name": "MUP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38734", "map_id": "P38734", "name": "MUP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHL036W", "map_id": "YHL036W", "name": "MUP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38158", "map_id": "P38158", "name": "MAL32", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR299W", "map_id": "YBR299W", "name": "MAL32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40884", "map_id": "P40884", "name": "IMA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL216C", "map_id": "YJL216C", "name": "IMA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CW41", "map_id": "P0CW41", "name": "IMA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL221C", "map_id": "YJL221C", "name": "IMA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CW40", "map_id": "P0CW40", "name": "IMA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL172C", "map_id": "YIL172C", "name": "IMA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08295", "map_id": "Q08295", "name": "IMA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL157C", "map_id": "YOL157C", "name": "IMA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769768", "map_id": "none", "name": "SLC26A3,6 exchange Cl- for HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10769765", "map_id": "none", "name": "SLC26A3,6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10777542", "map_id": "none", "name": "CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5673778", "map_id": "CHEBI:16283", "name": "CySS-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10777539", "map_id": "P17261", "name": "ERS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "YCR075C", "map_id": "YCR075C", "name": "ERS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10769759", "map_id": "none", "name": "Group 3 - Selective Cl- transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10769756", "map_id": "none", "name": "SLC26 chloride transporters", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10786838", "map_id": "none", "name": "SLC26A11 transports SO4(2-) from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10786835", "map_id": "P38359", "name": "SUL1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "YBR294W", "map_id": "YBR294W", "name": "SUL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10767238", "map_id": "none", "name": "ERK5 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10767234", "map_id": "P41808", "name": "phospho-SMK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10767236", "map_id": "P41808", "name": "phospho-SMK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10778793", "map_id": "none", "name": "Activated MAPKs phosphorylate MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778763", "map_id": "none", "name": "p-2S MAP2K1:p-2S MAPK2K2 heterodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10778790", "map_id": "none", "name": "p-2S,T MAP2K1:p-2S MAPK2K2 heterodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10778780", "map_id": "none", "name": "p-T,Y MAPK monomers and dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10779550", "map_id": "none", "name": "p-S MAPK6,4 binds MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775217", "map_id": "P36003", "name": "NNK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10779544", "map_id": "P41808", "name": "phospho-SMK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10779548", "map_id": "none", "name": "p-S MAPK6,4:MAKPAPK5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10780903", "map_id": "none", "name": "p-T182-MAPKAPK5 phoshphorylates DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10780891", "map_id": "none", "name": "p-T182 MAPKAPK5:DNAJB1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10780900", "map_id": "none", "name": "p-T182 MAPKAPK5:p-S149,S151, S171 DNAJB1 ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10779572", "map_id": "none", "name": "MAPK4,6 translocate to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779563", "map_id": "none", "name": "MAPK4,6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779557", "map_id": "none", "name": "MAPK4,6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10779570", "map_id": "P30822", "name": "CRM1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YGR218W", "map_id": "YGR218W", "name": "CRM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10779583", "map_id": "none", "name": "p-S115 MAPKAPK5 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779529", "map_id": "P36003", "name": "phospho-NNK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10779581", "map_id": "P36003", "name": "phospho-NNK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10779542", "map_id": "none", "name": "PKA phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779539", "map_id": "none", "name": "Protein Kinase A, catalytic subunits", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781177", "map_id": "none", "name": "SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10781173", "map_id": "none", "name": "Homologues of SEPT7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10779577", "map_id": "P36003", "name": "phospho-NNK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10779523", "map_id": "P41808", "name": "phospho-SMK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10781175", "map_id": "none", "name": "SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10779565", "map_id": "none", "name": "MAPK4,6 translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10780893", "map_id": "none", "name": "p-T182 MAPKAPK5 binds DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775708", "map_id": "P25294", "name": "SIS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10779526", "map_id": "none", "name": "PAK1,2,3 phosphorylates MAPK6,4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10779517", "map_id": "P41808", "name": "SMK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10779520", "map_id": "P41808", "name": "phospho-SMK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10779575", "map_id": "none", "name": "MAPK6 is degraded by the 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10779515", "map_id": "P41808", "name": "SMK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10781115", "map_id": "none", "name": "CDC14A,B bind MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781107", "map_id": "P41808", "name": "phospho-SMK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10781109", "map_id": "Q00684", "name": "CDC14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10781113", "map_id": "none", "name": "p-3S,T MAPK6:CDC14A,B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10781120", "map_id": "none", "name": "CDC14A,B dephosphorylate p-3S,T MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781117", "map_id": "none", "name": "MAPK6:CDC14A,B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10779555", "map_id": "none", "name": "p-S MAPK6,4 phosphorylate MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10779552", "map_id": "none", "name": "p-S MAPK6,4:p-T182 MAKPAPK5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10779579", "map_id": "none", "name": "p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10781140", "map_id": "none", "name": "MAPK6 binds CCND3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10781136", "map_id": "none", "name": "Homologues of CCND3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10779561", "map_id": "P41808", "name": "SMK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10781138", "map_id": "none", "name": "MAPK6:CCND3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10770806", "map_id": "none", "name": "MK2 phosphorylates ZFP36 (Tristetraproline, TTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770793", "map_id": "none", "name": "TTP:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P47976", "map_id": "P47976", "name": "phospho-CTH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR151C", "map_id": "YDR151C", "name": "phospho-CTH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38217", "map_id": "P38217", "name": "KAP104", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR017C", "map_id": "YBR017C", "name": "KAP104", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47977", "map_id": "P47977", "name": "phospho-TIS11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR136C", "map_id": "YLR136C", "name": "phospho-TIS11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10770785", "map_id": "none", "name": "Phosphorylated TTP:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10770831", "map_id": "none", "name": "Protein Kinase B/Akt phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770810", "map_id": "none", "name": "BRF1:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10770828", "map_id": "none", "name": "Phosphorylated BRF1 (Ser92, Ser203):mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10770803", "map_id": "none", "name": "ZFP36 (TTP) recruits RNA degradation activities", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770123", "map_id": "none", "name": "Exosome Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10770057", "map_id": "P53550", "name": "DCP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10770799", "map_id": "P22147", "name": "XRN1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10770050", "map_id": "Q12517", "name": "DCP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10770801", "map_id": "none", "name": "TTP:mRNA Degradation Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P22147", "map_id": "P22147", "name": "XRN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "XRN1", "map_id": "XRN1", "name": "XRN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770824", "map_id": "none", "name": "BRF1 Complex recruits RNA degradation activities", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770822", "map_id": "none", "name": "BRF1:mRNA Degradation Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10770795", "map_id": "none", "name": "ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770791", "map_id": "none", "name": "Homologues of ZFP36", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_450597", "map_id": "none", "name": "mRNA Transcript Targeted by Tristetraproline", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10770767", "map_id": "P38217", "name": "KAP104", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10770820", "map_id": "none", "name": "MK2 phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770818", "map_id": "none", "name": "Phosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10770839", "map_id": "none", "name": "Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770808", "map_id": "P47976", "name": "CTH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_450523", "map_id": "none", "name": "mRNA Transcript Targeted by BRF1", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10768801", "map_id": "none", "name": "EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768798", "map_id": "none", "name": "p-S52-EIF2S1:EIF2S2:EIF2S3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10768776", "map_id": "none", "name": "PERK dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P47042", "map_id": "P47042", "name": "IKS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJL057C", "map_id": "YJL057C", "name": "IKS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768778", "map_id": "none", "name": "Dimerization of PERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10768767", "map_id": "P47042", "name": "IKS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10771292", "map_id": "none", "name": "Loading of GABA into clathrin sculpted GABA transport vesicle lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_352011", "map_id": "CHEBI:59888", "name": "GABA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428571", "map_id": "CHEBI:59888", "name": "GABA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_917775", "compartment_display": "clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen", "complex": "false" }, { "id": "species_10771289", "map_id": "P47082", "name": "AVT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_917757", "compartment_display": "clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane", "complex": "false" }, { "id": "reaction_10771287", "map_id": "none", "name": "ALDH5A1 dehydrogenates SUCCSA to SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_880046", "map_id": "CHEBI:57706", "name": "SUCCSA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10771284", "map_id": "none", "name": "ALDH5A1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P38067", "map_id": "P38067", "name": "UGA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR006W", "map_id": "YBR006W", "name": "UGA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771335", "map_id": "none", "name": "PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10771332", "map_id": "none", "name": "PXLP-K357-ABAT dimer:2Fe-2S", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P17649", "map_id": "P17649", "name": "UGA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR019W", "map_id": "YGR019W", "name": "UGA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10777469", "map_id": "none", "name": "Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10777464", "map_id": "none", "name": "HSF1:HSP90:HDAC6:VCP:PTGES3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P28707", "map_id": "P28707", "name": "SBA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5324631", "map_id": "none", "name": "Ub-protein aggregates", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10775732", "map_id": "none", "name": "Homologues of HSF1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10775828", "map_id": "none", "name": "HSP90:HSP90", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10777466", "map_id": "none", "name": "HDAC6:VCP:protein aggregates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10775838", "map_id": "none", "name": "SIRT1 binds to HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775800", "map_id": "none", "name": "HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10769730", "map_id": "P06700", "name": "SIR2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10775802", "map_id": "none", "name": "SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10776963", "map_id": "none", "name": "Dissociation of HSF1:HSP90 complex in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776961", "map_id": "none", "name": "HSF1:HSP90:PTGES3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776953", "map_id": "P28707", "name": "SBA1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10776959", "map_id": "none", "name": "HSP90:HSP90", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776931", "map_id": "none", "name": "Homologues of HSF1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10776071", "map_id": "none", "name": "SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10776067", "map_id": "none", "name": "CCS:Zn2+:2xCu1+ dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:49552", "map_id": "CHEBI:49552", "name": "CHEBI:49552", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40202", "map_id": "P40202", "name": "CCS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CCS1", "map_id": "CCS1", "name": "CCS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10775367", "map_id": "none", "name": "SOD1:Zn2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10776069", "map_id": "none", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10776933", "map_id": "none", "name": "Trimerization of HSF1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10775810", "map_id": "none", "name": "HSF1 trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10787563", "map_id": "none", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775369", "map_id": "none", "name": "CCS:Zn2+:2xCu1+:SOD1:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10775817", "map_id": "none", "name": "SIRT1 deacetylates HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10775358", "map_id": "none", "name": "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775355", "map_id": "none", "name": "2xHC-SOD1:Zn2+:Cu2+ dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10776951", "map_id": "none", "name": "Phosphorylation of HSF1 at Ser326 induces transactivation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776917", "map_id": "none", "name": "p-S326-HSF1 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776948", "map_id": "none", "name": "mTORC1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P38873", "map_id": "P38873", "name": "KOG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR186C", "map_id": "YHR186C", "name": "KOG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775376", "map_id": "none", "name": "CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775373", "map_id": "none", "name": "CCS:Zn2+:Cu1+ dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10776841", "map_id": "none", "name": "MAPKAPK2 phosphorylates HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10776838", "map_id": "none", "name": "Homologues of p-S121-HSF1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10777933", "map_id": "none", "name": "ATP binding to HSP90 triggers conformation change", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775834", "map_id": "none", "name": "HSP90:STIP1:HSP70:nascent protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10777927", "map_id": "none", "name": "HSP90:ATP:STIP1:HSP70:nascent protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788859", "map_id": "none", "name": "RRAGA,B hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10788854", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "P25378", "map_id": "P25378", "name": "RHB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCR027C", "map_id": "YCR027C", "name": "RHB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53290", "map_id": "P53290", "name": "GTR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR163W", "map_id": "YGR163W", "name": "GTR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q00582", "map_id": "Q00582", "name": "GTR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YML121W", "map_id": "YML121W", "name": "GTR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788856", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10776883", "map_id": "none", "name": "Secretion of SOD3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10776881", "map_id": "none", "name": "SOD3 tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10775345", "map_id": "none", "name": "SOD3 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10764183", "map_id": "none", "name": "2 H2O2 => O2 + 2 H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_10764180", "map_id": "none", "name": "CAT tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "reaction_10788844", "map_id": "none", "name": "RRAGC,D exchanges GTP for GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10788837", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10788841", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10775629", "map_id": "none", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_3341308", "map_id": "CHEBI:18421", "name": "O2-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "reaction_10788899", "map_id": "none", "name": "mTORC1 binds RHEB:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10765837", "map_id": "none", "name": "RHEB:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10788852", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10775719", "map_id": "none", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775714", "map_id": "none", "name": "HSP40:HSP70:ATP:nascent protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P25491", "map_id": "P25491", "name": "YDJ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL064C", "map_id": "YNL064C", "name": "YDJ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53940", "map_id": "P53940", "name": "APJ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL077W", "map_id": "YNL077W", "name": "APJ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10775716", "map_id": "none", "name": "HSP40:HSP70:ADP:nascent protein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10775712", "map_id": "none", "name": "HSP40s", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10776175", "map_id": "none", "name": "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_10776172", "map_id": "none", "name": "SOD1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "reaction_10775836", "map_id": "none", "name": "STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775822", "map_id": "P15705", "name": "STI1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10775760", "map_id": "none", "name": "Constitutive phosphorylation by GSK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775740", "map_id": "none", "name": "Homologues of p-S303-HSF1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10775757", "map_id": "none", "name": "Homologues of GSK3B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P50873", "map_id": "P50873", "name": "MRK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL079C", "map_id": "YDL079C", "name": "MRK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38615", "map_id": "P38615", "name": "RIM11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR139W", "map_id": "YMR139W", "name": "RIM11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P21965", "map_id": "P21965", "name": "MCK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL307C", "map_id": "YNL307C", "name": "MCK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775348", "map_id": "none", "name": "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_3299686", "map_id": "CHEBI:18421", "name": "O2.-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_351629", "map_id": "CHEBI:16240", "name": "H2O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_352327", "map_id": "CHEBI:15379", "name": "O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10775848", "map_id": "none", "name": "HSF1 trimer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775846", "map_id": "none", "name": "HSF1 trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10775875", "map_id": "none", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775871", "map_id": "none", "name": "HSP40:nascent protein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10775873", "map_id": "none", "name": "HSP70:ATP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10775865", "map_id": "none", "name": "Constitutive phosphorylation by pERK1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775856", "map_id": "none", "name": "Homologues of p-S307-HSF1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10775862", "map_id": "none", "name": "p-T,Y MAPK dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10775869", "map_id": "none", "name": "Dissociation of cytosolic HSF1:HSP90 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10775867", "map_id": "none", "name": "HSF1:HSP90:PTGES3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788872", "map_id": "none", "name": "RRAGC,D hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "reaction_10776919", "map_id": "none", "name": "HSF1-mediated gene expression", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776897", "map_id": "none", "name": "Heat shock inducible proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10776907", "map_id": "none", "name": "p-S230-HSF1 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10788874", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10788848", "map_id": "none", "name": "mTORC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10788850", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10775877", "map_id": "none", "name": "Trimerization of cytosolic HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10775337", "map_id": "none", "name": "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_3299683", "map_id": "CHEBI:18421", "name": "O2.-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113533", "map_id": "CHEBI:15379", "name": "O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_1614617", "map_id": "CHEBI:16240", "name": "H2O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10775334", "map_id": "none", "name": "SOD2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P00447", "map_id": "P00447", "name": "SOD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR008C", "map_id": "YHR008C", "name": "SOD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10775625", "map_id": "none", "name": "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_1655882", "map_id": "CHEBI:17858", "name": "GSSG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_1655887", "map_id": "CHEBI:16856", "name": "GSH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10775622", "map_id": "none", "name": "GSR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10769335", "map_id": "none", "name": "cGMP is degraded by PDEs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10769328", "map_id": "P06776", "name": "PDE2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10788618", "map_id": "none", "name": "p-T,Y MAPK dimers translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10778778", "map_id": "none", "name": "p-T,Y MAPKs dimerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10772586", "map_id": "none", "name": "p-T,Y MAPKs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788635", "map_id": "none", "name": "SGK phosphorylates SRF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10788623", "map_id": "P11746", "name": "MCM1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "YMR043W", "map_id": "YMR043W", "name": "phospho-MCM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788626", "map_id": "P11746", "name": "phospho-MCM1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10788632", "map_id": "none", "name": "Homologues of p-T256,S422-SGK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10771748", "map_id": "none", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10771743", "map_id": "none", "name": "SMG1:UPF1:EJC:Translated mRNP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38798", "map_id": "P38798", "name": "NMD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR077C", "map_id": "YHR077C", "name": "NMD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12099", "map_id": "Q12099", "name": "FAL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR021W", "map_id": "YDR021W", "name": "FAL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P48412", "map_id": "P48412", "name": "UPF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR072W", "map_id": "YGR072W", "name": "UPF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P30771", "map_id": "P30771", "name": "phospho-NAM7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR080C", "map_id": "YMR080C", "name": "phospho-NAM7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10771745", "map_id": "none", "name": "SMG1:Phosphorylated UPF1:EJC:Translated mRNP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10771733", "map_id": "none", "name": "SMG6 hydrolyzes mRNA with premature termination codon", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10771730", "map_id": "none", "name": "Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P40456", "map_id": "P40456", "name": "ESL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL151C", "map_id": "YIL151C", "name": "ESL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P17214", "map_id": "P17214", "name": "EST1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR233C", "map_id": "YLR233C", "name": "EST1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03466", "map_id": "Q03466", "name": "EBS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR206W", "map_id": "YDR206W", "name": "EBS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q00362", "map_id": "Q00362", "name": "CDC55", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGL190C", "map_id": "YGL190C", "name": "CDC55", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36168", "map_id": "P36168", "name": "ESL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR096W", "map_id": "YKR096W", "name": "ESL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P31383", "map_id": "P31383", "name": "TPD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL016W", "map_id": "YAL016W", "name": "TPD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10771693", "map_id": "none", "name": "mRNA Cleaved by SMG6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10771637", "map_id": "none", "name": "Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10771633", "map_id": "none", "name": "Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10771609", "map_id": "P30771", "name": "NAM7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10771635", "map_id": "none", "name": "UPF1:eRF3 Complex on Translated mRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10777503", "map_id": "none", "name": "CLAT:AP1:CLVS bind PI(3,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_5334668", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "species_10777499", "map_id": "none", "name": "CLAT:AP1:CLVS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "Q12028", "map_id": "Q12028", "name": "APL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPR029C", "map_id": "YPR029C", "name": "APL4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P35181", "map_id": "P35181", "name": "APS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR170C", "map_id": "YLR170C", "name": "APS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10777501", "map_id": "none", "name": "CLAT:AP1:CLVS:PI(3,5)P2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20592", "compartment_display": "clathrin-coated endocytic vesicle", "complex": "true" }, { "id": "reaction_10764574", "map_id": "none", "name": "MAP2K1 binds MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764553", "map_id": "P06784", "name": "phospho-STE7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10764570", "map_id": "none", "name": "Homologues of MAPK3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10764621", "map_id": "none", "name": "Dissociation of p-T,Y-MAPK3:MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764598", "map_id": "none", "name": "Homologues of p-T202,Y204-MAPK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10786323", "map_id": "none", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10786276", "map_id": "P48510", "name": "DSK2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YMR276W", "map_id": "YMR276W", "name": "DSK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10786319", "map_id": "none", "name": "EPS15,EPN1,EPN2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q07872", "map_id": "Q07872", "name": "ENT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLL038C", "map_id": "YLL038C", "name": "ENT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05785", "map_id": "Q05785", "name": "ENT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR206W", "map_id": "YLR206W", "name": "ENT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q03769", "map_id": "Q03769", "name": "ENT5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR153C", "map_id": "YDR153C", "name": "ENT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47160", "map_id": "P47160", "name": "ENT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR125C", "map_id": "YJR125C", "name": "ENT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12518", "map_id": "Q12518", "name": "ENT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL161W", "map_id": "YDL161W", "name": "ENT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10786321", "map_id": "none", "name": "UNQLNs:UIM proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P48510", "map_id": "P48510", "name": "DSK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10786337", "map_id": "none", "name": "AP-2 directly binds some endocytic cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10786331", "map_id": "none", "name": "Homologues of PolyUb-CFTR", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10786030", "map_id": "none", "name": "AP-2 Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786333", "map_id": "none", "name": "AP-2:cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10786335", "map_id": "none", "name": "AP2:chlorpromazine", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_9648300", "map_id": "LigandDisplayForward?ligandId=83", "name": "chlorpromazine", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10786206", "map_id": "none", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10781023", "map_id": "Q03919", "name": "RUB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10786204", "map_id": "none", "name": "STON2,1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38700", "map_id": "P38700", "name": "APM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHL019C", "map_id": "YHL019C", "name": "APM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10786190", "map_id": "none", "name": "NEDD8-STONs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10786140", "map_id": "none", "name": "AAK1 phosphorylates AP-2 mu subunit at T156", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10786130", "map_id": "none", "name": "PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P25623", "map_id": "P25623", "name": "SYP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCR030C", "map_id": "YCR030C", "name": "SYP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53974", "map_id": "P53974", "name": "ARK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YNL020C", "map_id": "YNL020C", "name": "ARK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P38080", "map_id": "P38080", "name": "AKL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR059C", "map_id": "YBR059C", "name": "AKL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05080", "map_id": "Q05080", "name": "HOF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YMR032W", "map_id": "YMR032W", "name": "HOF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P43556", "map_id": "P43556", "name": "RGD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YFL047W", "map_id": "YFL047W", "name": "RGD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40494", "map_id": "P40494", "name": "PRK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YIL095W", "map_id": "YIL095W", "name": "PRK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10786137", "map_id": "none", "name": "PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10786527", "map_id": "none", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10773422", "map_id": "P38994", "name": "MSS4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10786779", "map_id": "none", "name": "Initial binding of AP-2 and clathrin to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10769532", "map_id": "none", "name": "Clathrin Triskelion", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786116", "map_id": "none", "name": "PI(4,5)P2:AP-2:clathrin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10786466", "map_id": "none", "name": "PICALM binds R-SNAREs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10786449", "map_id": "none", "name": "VAMP2,3,8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10786462", "map_id": "none", "name": "PICALMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P38856", "map_id": "P38856", "name": "YAP1801", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YHR161C", "map_id": "YHR161C", "name": "YAP1801", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P53309", "map_id": "P53309", "name": "YAP1802", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YGR241C", "map_id": "YGR241C", "name": "YAP1802", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10786464", "map_id": "none", "name": "PICALM:VAMP2,3,8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10789079", "map_id": "none", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10786167", "map_id": "none", "name": "FCHo proteins bind nascent clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10786094", "map_id": "none", "name": "FCHO1,2 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786063", "map_id": "none", "name": "ITSNs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786110", "map_id": "none", "name": "Homologues of REPS1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786102", "map_id": "none", "name": "Homologues of EPS15", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786124", "map_id": "none", "name": "Homologues of SGIP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10786126", "map_id": "none", "name": "PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10765839", "map_id": "none", "name": "GTP loading by Rheb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10765835", "map_id": "none", "name": "RHEB:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10778419", "map_id": "none", "name": "Rag dimer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778402", "map_id": "none", "name": "RRAGA, RRAGB:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10778415", "map_id": "none", "name": "RRAGC,RRAGD:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10778417", "map_id": "none", "name": "RagA,B:GTP:RagC,D:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10768750", "map_id": "none", "name": "Phosphorylated AMPK binds AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10767428", "map_id": "none", "name": "p-AMPK heterotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10787858", "map_id": "none", "name": "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10787850", "map_id": "none", "name": "Mitochondrial targeting peptides (from matrix proteins)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P53193", "map_id": "P53193", "name": "JAC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "JAC1", "map_id": "JAC1", "name": "JAC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P19882", "map_id": "P19882", "name": "HSP60", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "HSP60", "map_id": "HSP60", "name": "HSP60", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10787855", "map_id": "P32898", "name": "CYM1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "YDR430C", "map_id": "YDR430C", "name": "CYM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10773966", "map_id": "none", "name": "TIMM9:TIMM10 transfers proteins to TIMM22", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10773936", "map_id": "Q12328", "name": "TIM22", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10773958", "map_id": "none", "name": "TIMM9:TIMM10:Protein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P32897", "map_id": "P32897", "name": "TIM23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "TIM23", "map_id": "TIM23", "name": "TIM23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74700", "map_id": "O74700", "name": "TIM9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "TIM9", "map_id": "TIM9", "name": "TIM9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39515", "map_id": "P39515", "name": "TIM17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "TIM17", "map_id": "TIM17", "name": "TIM17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12328", "map_id": "Q12328", "name": "TIM22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "TIM22", "map_id": "TIM22", "name": "TIM22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87108", "map_id": "P87108", "name": "TIM10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "TIM10", "map_id": "TIM10", "name": "TIM10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06510", "map_id": "Q06510", "name": "TAZ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "TAZ1", "map_id": "TAZ1", "name": "TAZ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10773960", "map_id": "O74700", "name": "TIM9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10773964", "map_id": "none", "name": "TIMM9:TIMM10:TIMM10B:TIM22:Protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10787754", "map_id": "none", "name": "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787751", "map_id": "none", "name": "GLUT14 / SLC2A14 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10771210", "map_id": "none", "name": "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_914003", "map_id": "CHEBI:16264", "name": "UDP-GlcNAc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10771207", "map_id": "P40004", "name": "YEA4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "YEL004W", "map_id": "YEL004W", "name": "YEA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10777534", "map_id": "none", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_114632", "map_id": "CHEBI:18420", "name": "Mg2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10777531", "map_id": "none", "name": "Homologues of MAGT1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10787772", "map_id": "none", "name": "GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10777511", "map_id": "none", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10777508", "map_id": "Q02783", "name": "MFM1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "YPL060W", "map_id": "YPL060W", "name": "MFM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770623", "map_id": "none", "name": "GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10770619", "map_id": "none", "name": "GLUT1:ATP tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10770617", "map_id": "none", "name": "GLUT1 / SLC2A1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10787104", "map_id": "none", "name": "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8932838", "map_id": "none", "name": "L-Arg,L-His,L-Lys", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_8932842", "map_id": "none", "name": "L-Arg,L-His,L-Lys", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10787101", "map_id": "Q12010", "name": "YPQ1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "YOL092W", "map_id": "YOL092W", "name": "YPQ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771591", "map_id": "none", "name": "Acidification of Tf:TfR1 containing endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "reaction_10771200", "map_id": "none", "name": "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_727753", "map_id": "CHEBI:57288", "name": "Ac-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10771197", "map_id": "P38318", "name": "SLC33A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "YBR220C", "map_id": "YBR220C", "name": "SLC33A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10770621", "map_id": "none", "name": "GLUT1 tetramer binds 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10769976", "map_id": "none", "name": "SLC2A9 transports Fru, Glc, urate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429078", "map_id": "none", "name": "Fru,Glc,urate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:17775", "map_id": "CHEBI:17775", "name": "CHEBI:17775", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_429148", "map_id": "none", "name": "Fru,Glc,urate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10769973", "map_id": "none", "name": "Homologues of SLC2A9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10771269", "map_id": "none", "name": "SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_879603", "map_id": "none", "name": "T3,T4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:18332", "map_id": "CHEBI:18332", "name": "CHEBI:18332", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28774", "map_id": "CHEBI:28774", "name": "CHEBI:28774", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_879628", "map_id": "none", "name": "T3,T4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10771266", "map_id": "none", "name": "SLC16A2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10777522", "map_id": "none", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10777519", "map_id": "P48439", "name": "OST3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10787770", "map_id": "none", "name": "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787767", "map_id": "none", "name": "GLUT4 / SLC2A4 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10769950", "map_id": "none", "name": "GLUT7 and GLUT11 transport glucose and fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_428819", "map_id": "none", "name": "hexoses transported by GLUT7/11", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_428802", "map_id": "none", "name": "hexoses transported by GLUT7/11", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10769947", "map_id": "none", "name": "GLUT7/11", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10770626", "map_id": "none", "name": "GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10771213", "map_id": "none", "name": "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_742353", "map_id": "CHEBI:16082", "name": "UDP-Xyl", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_742361", "map_id": "CHEBI:16082", "name": "UDP-Xyl", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10787759", "map_id": "none", "name": "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10787756", "map_id": "none", "name": "GLUT3 / SLC2A3 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10777514", "map_id": "none", "name": "GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10787519", "map_id": "none", "name": "SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_8949220", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2889072", "map_id": "CHEBI:29101", "name": "Na+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_8949232", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_2889083", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10787516", "map_id": "P47144", "name": "ECM27", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10764584", "map_id": "none", "name": "MAP2K2 binds MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10764580", "map_id": "P16892", "name": "FUS3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10764578", "map_id": "P06784", "name": "phospho-STE7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10764623", "map_id": "none", "name": "Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10788776", "map_id": "none", "name": "PTPN7 dephosphorylates p-T,Y-MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788755", "map_id": "none", "name": "PTPN7:p-T,Y-MAPK dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P25044", "map_id": "P25044", "name": "PTP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL230W", "map_id": "YDL230W", "name": "PTP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P29461", "map_id": "P29461", "name": "PTP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR208W", "map_id": "YOR208W", "name": "PTP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40048", "map_id": "P40048", "name": "PTP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YER075C", "map_id": "YER075C", "name": "PTP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788773", "map_id": "none", "name": "PTPN7:p-T-MAPK dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10778883", "map_id": "none", "name": "Cytosolic DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10778842", "map_id": "none", "name": "MAPK monomers and dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10778880", "map_id": "none", "name": "cytosolic MAPK DUSPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10778786", "map_id": "none", "name": "Phosphorylated MAPKs translocate into the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778784", "map_id": "none", "name": "p-T,Y MAPK monomers and dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10778836", "map_id": "none", "name": "Nuclear DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10778795", "map_id": "none", "name": "MAPK monomers and dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10778833", "map_id": "none", "name": "nuclear MAPK DUSPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10788930", "map_id": "none", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9647934", "map_id": "pubchem.compound:45100481", "name": "Palmostatin B", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10788928", "map_id": "none", "name": "Palmostatin B:LYPLA1 dimer, ABHD17A,B,C", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10778776", "map_id": "none", "name": "MAP2Ks phosphorylate MAPK at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10778771", "map_id": "none", "name": "IL17RD:p-2S MAP2Ks:MAPKs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10778773", "map_id": "none", "name": "IL17RD:p-2S MAP2Ks:p-T,Y MAPKs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10788926", "map_id": "none", "name": "FNTB inhibitors bind FNTA:FNTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9653479", "map_id": "none", "name": "FNTB inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "LigandDisplayForward?ligandId=6531", "map_id": "LigandDisplayForward?ligandId=6531", "name": "LigandDisplayForward?ligandId=6531", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=8025", "map_id": "LigandDisplayForward?ligandId=8025", "name": "LigandDisplayForward?ligandId=8025", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=8024", "map_id": "LigandDisplayForward?ligandId=8024", "name": "LigandDisplayForward?ligandId=8024", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "pubchem.compound:216453", "map_id": "pubchem.compound:216453", "name": "pubchem.compound:216453", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=8028", "map_id": "LigandDisplayForward?ligandId=8028", "name": "LigandDisplayForward?ligandId=8028", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=8026", "map_id": "LigandDisplayForward?ligandId=8026", "name": "LigandDisplayForward?ligandId=8026", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=8030", "map_id": "LigandDisplayForward?ligandId=8030", "name": "LigandDisplayForward?ligandId=8030", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788922", "map_id": "none", "name": "FNTA:FNTB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P29703", "map_id": "P29703", "name": "RAM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKL019W", "map_id": "YKL019W", "name": "RAM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22007", "map_id": "P22007", "name": "RAM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDL090C", "map_id": "YDL090C", "name": "RAM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10788924", "map_id": "none", "name": "FNTA:FNTB:FTase inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10788778", "map_id": "none", "name": "PTPN7 binds p-T,Y-MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10788753", "map_id": "none", "name": "Homologues of PTPN7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10785442", "map_id": "none", "name": "PLA2s hydrolyze phospholipids at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_6814303", "map_id": "CHEBI:35366", "name": "fatty acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8848483", "map_id": "CHEBI:17504", "name": "2-lysophosphatidylcholine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10785464", "map_id": "none", "name": "LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10785461", "map_id": "Q08750", "name": "MUM3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10785255", "map_id": "none", "name": "SNAPs and NSF hexamer bind cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10785251", "map_id": "none", "name": "STX10:STX16:VTI1A:VAMP3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "Q03322", "map_id": "Q03322", "name": "TLG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YDR468C", "map_id": "YDR468C", "name": "TLG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08144", "map_id": "Q08144", "name": "TLG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOL018C", "map_id": "YOL018C", "name": "TLG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785253", "map_id": "none", "name": "STX10:STX16:VTI1A:VAMP3:NSF hexamer:SNAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10785195", "map_id": "none", "name": "SYS1 binds AcM-ARFRP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10785165", "map_id": "P41544", "name": "SYS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "false" }, { "id": "YJL004C", "map_id": "YJL004C", "name": "SYS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785193", "map_id": "none", "name": "AcM-ARFRP1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q02804", "map_id": "Q02804", "name": "ARL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ARL3", "map_id": "ARL3", "name": "ARL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785173", "map_id": "none", "name": "AcM-ARFRP1:GTP:SYS1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "P41544", "map_id": "P41544", "name": "SYS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10785206", "map_id": "none", "name": "ARL1 recruits TGN Golgin homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10785202", "map_id": "none", "name": "TMF1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P47166", "map_id": "P47166", "name": "SGM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR134C", "map_id": "YJR134C", "name": "SGM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785187", "map_id": "none", "name": "AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "P38116", "map_id": "P38116", "name": "ARL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBR164C", "map_id": "YBR164C", "name": "ARL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785204", "map_id": "none", "name": "AcG-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:TGN Golgin dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10785104", "map_id": "none", "name": "RIC1:RGP1 recruits RAB6:GDP to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10785096", "map_id": "none", "name": "RIC1:RGP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "species_10785084", "map_id": "none", "name": "RAB6:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10785102", "map_id": "none", "name": "RAB6:GDP:RIC1:RGP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10785314", "map_id": "none", "name": "cis-SNARE binds SNAPs and NSF hexamer at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10785310", "map_id": "none", "name": "STX6:STX16:VTI1A:VAMP4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "P31377", "map_id": "P31377", "name": "SYN8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YAL014C", "map_id": "YAL014C", "name": "SYN8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785312", "map_id": "none", "name": "STX6:STX16:VTI1A:VAMP4:NSF hexamer:3xSNAPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10785111", "map_id": "none", "name": "RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10785108", "map_id": "none", "name": "RAB6:GTP:RIC1:RGP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10785189", "map_id": "none", "name": "ARFRP1 recruits ARL1 to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10785181", "map_id": "none", "name": "MyrG-ARL1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10785258", "map_id": "none", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10785249", "map_id": "P33328", "name": "SNC2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "false" }, { "id": "species_10785245", "map_id": "Q08144", "name": "TLG2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "false" }, { "id": "species_10785247", "map_id": "Q04338", "name": "VTI1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "false" }, { "id": "species_10785240", "map_id": "Q03322", "name": "TLG1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "false" }, { "id": "reaction_10768386", "map_id": "none", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768358", "map_id": "none", "name": "Arf1-GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10768366", "map_id": "none", "name": "Arf1-GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10768579", "map_id": "none", "name": "Vamp7 associated Lysosome to Plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768561", "map_id": "none", "name": "Homologues of SNAP23", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10768567", "map_id": "none", "name": "Homologues of STX4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10768572", "map_id": "Q12255", "name": "NYV1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "YLR093C", "map_id": "YLR093C", "name": "NYV1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10768574", "map_id": "Q12255", "name": "NYV1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10768576", "map_id": "none", "name": "Vamp7:SNAP23:Syn4 Plasma membrane vesicle docking and fusion complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q12255", "map_id": "Q12255", "name": "NYV1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10768619", "map_id": "none", "name": "Vamp2 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10768608", "map_id": "none", "name": "Homologues of VAMP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "true" }, { "id": "species_10768614", "map_id": "none", "name": "Homologues of VAMP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10768616", "map_id": "none", "name": "Vamp2:SNAP23:Syn4 Secretory granule docking and fusion complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10768602", "map_id": "none", "name": "Vamp8 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768591", "map_id": "none", "name": "Homologues of VAMP8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "true" }, { "id": "species_10768597", "map_id": "none", "name": "Homologues of VAMP8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10768599", "map_id": "none", "name": "Vamp8:SNAP23:Syn4 Secretory granule docking and fusion complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10776489", "map_id": "none", "name": "NLK translocates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10776483", "map_id": "none", "name": "pT298-NLK dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10776487", "map_id": "none", "name": "pT298-NLK dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10776538", "map_id": "none", "name": "Translocation of NFATC1:CaN:CaM to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10776532", "map_id": "none", "name": "NFATC1:CaN:CaM", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10776536", "map_id": "none", "name": "NFATC1:CaN:CaM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10771589", "map_id": "none", "name": "MVB Vesicle Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10771585", "map_id": "none", "name": "ESCRT-II/Cargo Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "Q06696", "map_id": "Q06696", "name": "VPS36", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR417W", "map_id": "YLR417W", "name": "VPS36", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12483", "map_id": "Q12483", "name": "SNF8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL002C", "map_id": "YPL002C", "name": "SNF8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47142", "map_id": "P47142", "name": "VPS25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YJR102C", "map_id": "YJR102C", "name": "VPS25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10771444", "map_id": "none", "name": "ESCRT-III/Cargo Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "species_10771583", "map_id": "none", "name": "ESCRT-II", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10771539", "map_id": "none", "name": "ESCRT Disassembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_10771364", "map_id": "Q03390", "name": "VPS60", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10771520", "map_id": "none", "name": "Ubiquinated and PIP3 Endosmal Membrane Bound Cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane", "complex": "true" }, { "id": "species_10771359", "map_id": "Q04272", "name": "VPS20", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10771350", "map_id": "P39929", "name": "SNF7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10771345", "map_id": "P36095", "name": "VPS24", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10771340", "map_id": "P36108", "name": "DID4", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10771536", "map_id": "none", "name": "Vps/Vta1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q06263", "map_id": "Q06263", "name": "VTA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR181C", "map_id": "YLR181C", "name": "VTA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771587", "map_id": "none", "name": "Cargo Sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10771566", "map_id": "none", "name": "ESCRT-I/Cargo Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "Q02767", "map_id": "Q02767", "name": "VPS28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YPL065W", "map_id": "YPL065W", "name": "VPS28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q99176", "map_id": "Q99176", "name": "SRN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YLR119W", "map_id": "YLR119W", "name": "SRN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25604", "map_id": "P25604", "name": "STP22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YCL008C", "map_id": "YCL008C", "name": "STP22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10771564", "map_id": "none", "name": "ESCRT-I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10772483", "map_id": "none", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10772463", "map_id": "P27895", "name": "CIN8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YEL061C", "map_id": "YEL061C", "name": "CIN8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10772465", "map_id": "none", "name": "Kinesin-5 homotetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P27895", "map_id": "P27895", "name": "CIN8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10774270", "map_id": "none", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10774268", "map_id": "none", "name": "PDPK1:PIP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10785347", "map_id": "none", "name": "NSF and SNAPs bind the cis-SNARE at the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10785343", "map_id": "none", "name": "STX:PalmC-YKT6:BET1L:GOSR1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10785345", "map_id": "none", "name": "STX5:PalmC-YKT6:BET1L:GOSR1:NSF hexamer:3xSNAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10785368", "map_id": "none", "name": "ARF1:GTP binds Golgin TRIP11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10785364", "map_id": "none", "name": "TRIP11:cargo", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_432051", "compartment_display": "transport vesicle", "complex": "true" }, { "id": "Q12234", "map_id": "Q12234", "name": "RUD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YOR216C", "map_id": "YOR216C", "name": "RUD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10785366", "map_id": "none", "name": "ARF1:GTP:TRIP11:cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10785424", "map_id": "none", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10785394", "map_id": "none", "name": "CYTH1,2,3,4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10785422", "map_id": "none", "name": "ARF1:GTP:CYTH1,2,3,4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10785431", "map_id": "none", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10785428", "map_id": "none", "name": "ARF1:GDP:CYTH1,2,3,4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10785350", "map_id": "none", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "reaction_10772494", "map_id": "none", "name": "Mitofusins trans-interact linking mitochondria prior to fusion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10772488", "map_id": "P38297", "name": "FZO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10772492", "map_id": "none", "name": "Mitofusin complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10772555", "map_id": "none", "name": "EHD proteins interact with Rabenosyn-5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_10772546", "map_id": "none", "name": "C-terminal EH domain containing proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "P32790", "map_id": "P32790", "name": "SLA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YBL007C", "map_id": "YBL007C", "name": "SLA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36115", "map_id": "P36115", "name": "IRS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "YKR019C", "map_id": "YKR019C", "name": "IRS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10772551", "map_id": "P32609", "name": "PEP7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "false" }, { "id": "YDR323C", "map_id": "YDR323C", "name": "PEP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10772553", "map_id": "none", "name": "C-terminal EH domain containing proteins:Rabenosyn-5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "P32609", "map_id": "P32609", "name": "PEP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10772520", "map_id": "none", "name": "Adenylate Kinase 3 is a GTP-AMP phosphotransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113573", "map_id": "CHEBI:37565", "name": "GTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113525", "map_id": "CHEBI:58189", "name": "GDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10772517", "map_id": "P26364", "name": "ADK2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10772572", "map_id": "none", "name": "DOCKs bind to RhoGEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10768888", "map_id": "P19073", "name": "CDC42", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772560", "map_id": "Q06409", "name": "DCK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10772570", "map_id": "none", "name": "DOCK-GEFs:RAC1, CDC42", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10772503", "map_id": "none", "name": "Dual-specific AKAPs bind type I and II PKA regulatory subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10772499", "map_id": "Q08760", "name": "RAX1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "YOR301W", "map_id": "YOR301W", "name": "RAX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10772501", "map_id": "none", "name": "Dual-specific AKAPs:PKA tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08760", "map_id": "Q08760", "name": "RAX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10771252", "map_id": "none", "name": "F-actin capping protein is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763295" ], "products": [ "species_10763299", "species_10763212" ], "modifiers": [], "additional_components": [ "Q01080", "YNL248C", "P20434", "RPB5", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P46669", "YOR340C", "P07703", "RPC40", "P32776", "YDR311W", "P36070", "YKL125W", "P06242", "YDL108W", "P13393", "SPT15", "Q04673", "YLR005W", "P10964", "YOR341W", "Q00578", "YIL143C", "P20436", "RPB8", "Q03290", "YDR460W", "Q12004", "YPR056W", "P40992", "YJL025W", "Q02939", "YPL122C", "P32529", "YJR063W", "P40422", "RPC10", "P22139", "RPB10", "P22138", "YPR010C", "P06839", "RAD3", "Q01080", "YNL248C", "P20434", "RPB5", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P46669", "YOR340C", "P07703", "RPC40", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "Q04673", "YLR005W", "P10964", "YOR341W", "Q00578", "YIL143C", "P20436", "RPB8", "Q03290", "YDR460W", "Q12004", "YPR056W", "P40992", "YJL025W", "Q02939", "YPL122C", "P32529", "YJR063W", "P40422", "RPC10", "P22139", "RPB10", "P22138", "YPR010C", "P06839", "RAD3", "YKL125W" ] }, "reaction_10763216": { "compartment": "compartment_7660", "id": "reaction_10763216", "reactome": "R-SCE-73757", "name": "Binding of RRN3 to RNA Polymerase I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763207", "species_10763212" ], "products": [ "species_10763214" ], "modifiers": [], "additional_components": [ "P10964", "YOR341W", "Q01080", "YNL248C", "P20434", "RPB5", "P20436", "RPB8", "P20435", "RPO26", "P32529", "YJR063W", "P40422", "RPC10", "P46669", "YOR340C", "P07703", "RPC40", "P22139", "RPB10", "P22138", "YPR010C", "YKL125W", "P10964", "YOR341W", "Q01080", "YNL248C", "P20434", "RPB5", "P20436", "RPB8", "P20435", "RPO26", "P32529", "YJR063W", "P40422", "RPC10", "P46669", "YOR340C", "P07703", "RPC40", "P22139", "RPB10", "P22138", "YPR010C", "P36070", "YKL125W" ] }, "reaction_10760927": { "compartment": "compartment_7660", "id": "reaction_10760927", "reactome": "R-SCE-69053", "name": "RFC binding displaces Pol Alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760830", "species_10760923" ], "products": [ "species_10760925" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P40348", "YJR068W", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "P38121", "YBL035C", "P13382", "YNL102W", "P40348", "YJR068W", "P10363", "YIR008C", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P20457", "YKL045W", "P38629", "YNL290W" ] }, "reaction_10760938": { "compartment": "compartment_7660", "id": "reaction_10760938", "reactome": "R-SCE-69063", "name": "Loading of PCNA - Sliding Clamp Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10760925", "species_10760934" ], "products": [ "species_113582", "species_10760936" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P40348", "YJR068W", "P10363", "YIR008C", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P20457", "YKL045W", "P38629", "YNL290W", "P15873", "YBR088C", "P38121", "YBL035C", "P13382", "YNL102W", "P40348", "YJR068W", "P10363", "YIR008C", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P20457", "YKL045W", "P38629", "YNL290W" ] }, "reaction_10760942": { "compartment": "compartment_7660", "id": "reaction_10760942", "reactome": "R-SCE-69068", "name": "RFC dissociates after sliding clamp formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760936" ], "products": [ "species_10760940", "species_10760923" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P40348", "YJR068W", "P10363", "YIR008C", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P20457", "YKL045W", "P38629", "YNL290W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P15873", "YBR088C", "P20457", "YKL045W", "P40348", "YJR068W", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W" ] }, "reaction_10773145": { "compartment": "compartment_12045", "id": "reaction_10773145", "reactome": "R-SCE-1482856", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[5]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10773142", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10773130": { "compartment": "compartment_12045", "id": "reaction_10773130", "reactome": "R-SCE-1482827", "name": "PC is hydrolyzed to 2-acyl LPC by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_975614", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10772925": { "compartment": "compartment_12045", "id": "reaction_10772925", "reactome": "R-SCE-1482533", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_1500578" ], "products": [ "species_76194", "species_426925" ], "modifiers": [ [ "species_10772920", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10773122": { "compartment": "compartment_12045", "id": "reaction_10773122", "reactome": "R-SCE-1482816", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10772968": { "compartment": "compartment_12045", "id": "reaction_10772968", "reactome": "R-SCE-1482547", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_1500578" ], "products": [ "species_76194", "species_426925" ], "modifiers": [ [ "species_10772920", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10773151": { "compartment": "compartment_12045", "id": "reaction_10773151", "reactome": "R-SCE-1482862", "name": "PC is hydrolysed to 2-acyl LPC by PLA2[7]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_975614", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10774233": { "compartment": "compartment_7660", "id": "reaction_10774233", "reactome": "R-SCE-2172678", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10774226", "species_113685" ], "products": [ "species_159942", "species_10774230", "species_159939", "species_29478" ], "modifiers": [ [ "species_10774226", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "species_111793", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "species_111793", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "species_111793", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10777844": { "compartment": "compartment_876", "id": "reaction_10777844", "reactome": "R-SCE-5607734", "name": "PKC-delta translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777274", "species_112275" ], "products": [ "species_10777842" ], "modifiers": [], "additional_components": [ "YBL105C", "species_112275", "P24583", "YBL105C" ] }, "reaction_10774717": { "compartment": "compartment_70101", "id": "reaction_10774717", "reactome": "R-SCE-2730867", "name": "Translocation of CaN:CaM:NFAT to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774691" ], "products": [ "species_10774715" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C", "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C" ] }, "reaction_10777848": { "compartment": "compartment_876", "id": "reaction_10777848", "reactome": "R-SCE-5607746", "name": "PKC-delta is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777842" ], "products": [ "species_10777846" ], "modifiers": [], "additional_components": [ "species_112275", "P24583", "YBL105C", "species_112275", "P24583", "YBL105C" ] }, "reaction_10774719": { "compartment": "compartment_70101", "id": "reaction_10774719", "reactome": "R-SCE-2730872", "name": "Activation of Calcineurin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767628", "species_74016", "species_10773995" ], "products": [ "species_10774687" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_74016", "species_158417", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C", "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C" ] }, "reaction_10777840": { "compartment": "compartment_70101", "id": "reaction_10777840", "reactome": "R-SCE-5607721", "name": "Activation of NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769138" ], "products": [ "species_10769138" ], "modifiers": [], "additional_components": [ "YCR073C", "YCR073C" ] }, "reaction_10774165": { "compartment": "compartment_70101", "id": "reaction_10774165", "reactome": "R-SCE-2162078", "name": "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161185", "species_29360" ], "products": [ "species_70106", "species_73473", "species_2162081" ], "modifiers": [ [ "species_10762111", "catalyst" ] ], "additional_components": [ "species_158417", "P32771", "YDL168W" ] }, "reaction_10760457": { "compartment": "compartment_7660", "id": "reaction_10760457", "reactome": "R-SCE-68944", "name": "Orc1 is phosphorylated by cyclin A/CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760396", "species_29358" ], "products": [ "species_113582", "species_10760408", "species_10760404" ], "modifiers": [ [ "species_10760454", "catalyst" ] ], "additional_components": [ "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P32833", "ORC2", "P54791", "ORC4", "P30665", "MCM4", "P54784", "phospho-ORC1", "P09119", "CDC6", "P53091", "MCM6", "P50874", "ORC5", "P29496", "MCM5", "P54790", "ORC3", "P24279", "MCM3", "P29469", "MCM2", "P32833", "ORC2", "P38132", "MCM7", "P54791", "ORC4", "P30665", "MCM4", "P09119", "CDC6", "P53091", "MCM6", "P50874", "ORC5", "P29496", "MCM5", "P54790", "ORC3", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760888": { "compartment": "compartment_7660", "id": "reaction_10760888", "reactome": "R-SCE-69006", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760843" ], "products": [ "species_10760886" ], "modifiers": [], "additional_components": [] }, "reaction_10760562": { "compartment": "compartment_7660", "id": "reaction_10760562", "reactome": "R-SCE-68946", "name": "Phosphorylated Orc1 is ubiquitinated while still associated with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760404", "species_10760537" ], "products": [ "species_10760540" ], "modifiers": [ [ "species_10760559", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W" ] }, "reaction_10760828": { "compartment": "compartment_70101", "id": "reaction_10760828", "reactome": "R-SCE-68948", "name": "Ubiquitinated Orc1 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760564" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10760566": { "compartment": "compartment_7660", "id": "reaction_10760566", "reactome": "R-SCE-68947", "name": "Ubiquitinated Orc1 enters the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760540" ], "products": [ "species_10760564" ], "modifiers": [], "additional_components": [] }, "reaction_10760896": { "compartment": "compartment_7660", "id": "reaction_10760896", "reactome": "R-SCE-69019", "name": "Mcm4,6,7 trimer forms and associates with the replication fork", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760363" ], "products": [ "species_10760359", "species_10760355", "species_10760349", "species_10760335" ], "modifiers": [], "additional_components": [ "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29496", "MCM5", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6" ] }, "reaction_10760884": { "compartment": "compartment_7660", "id": "reaction_10760884", "reactome": "R-SCE-69005", "name": "Cdc6 protein is phosphorylated by CDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10760214" ], "products": [ "species_113582", "species_10760843" ], "modifiers": [ [ "species_10760881", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760894": { "compartment": "compartment_70101", "id": "reaction_10760894", "reactome": "R-SCE-69016", "name": "Ubiquitinated Cdc6 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760892" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P09119", "CDC6", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10765258": { "compartment": "compartment_70101", "id": "reaction_10765258", "reactome": "R-SCE-114553", "name": "Activation of conventional Protein Kinase C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_33625", "species_10765240", "species_114519" ], "products": [ "species_10765256" ], "modifiers": [ [ "species_114519", "catalyst" ] ], "additional_components": [ "YBL105C", "species_33625", "P24583", "YBL105C", "species_74016", "species_6797635" ] }, "reaction_10769689": { "compartment": "compartment_70101", "id": "reaction_10769689", "reactome": "R-SCE-426043", "name": "2-AG hydrolysis to arachidonate by MAGL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426030", "species_29356" ], "products": [ "species_70106", "species_76116", "species_422506" ], "modifiers": [ [ "species_10769686", "catalyst" ] ], "additional_components": [ "YKL094W" ] }, "reaction_10765269": { "compartment": "compartment_70101", "id": "reaction_10765269", "reactome": "R-SCE-114683", "name": "Phosphorylation of Platelet Sec-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765263", "species_113592" ], "products": [ "species_29370", "species_10765266" ], "modifiers": [ [ "species_10765256", "catalyst" ] ], "additional_components": [ "YDR164C", "YDR164C", "species_33625", "P24583", "YBL105C", "species_74016", "species_6797635" ] }, "reaction_10771032": { "compartment": "compartment_70101", "id": "reaction_10771032", "reactome": "R-SCE-482772", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771010" ], "products": [ "species_10771030" ], "modifiers": [], "additional_components": [ "P60010", "YFL039C", "P06787", "YBR109C", "P09734", "YML124C", "Q12311", "YPR031W", "P46680", "YMR092C", "P30619", "YDR164C", "P00445", "SOD1", "P09733", "YML085C", "P60010", "YFL039C", "P06787", "YBR109C", "P09734", "YML124C", "Q12311", "YPR031W", "P46680", "YMR092C", "P30619", "YDR164C", "P00445", "SOD1", "P09733", "YML085C" ] }, "reaction_10769954": { "compartment": "compartment_70101", "id": "reaction_10769954", "reactome": "R-SCE-428941", "name": "P2Y purinoceptor 1 activates MAP kinase p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10769952" ], "products": [ "species_29370", "species_10766455" ], "modifiers": [ [ "species_10764870", "catalyst" ] ], "additional_components": [ "YLR113W", "YLR113W", "species_29438", "P10823", "YER020W" ] }, "reaction_10768515": { "compartment": "compartment_70101", "id": "reaction_10768515", "reactome": "R-SCE-354173", "name": "Activation of Rap1 by cytosolic GEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10768483" ], "products": [ "species_10768481", "species_29420" ], "modifiers": [ [ "species_10768512", "catalyst" ] ], "additional_components": [ "species_29420", "P13856", "YGR152C", "species_29438", "P13856", "YGR152C", "P04821", "YLR310C", "species_74016", "species_6797635", "P07866", "YAL024C", "P25300", "YCR038C" ] }, "reaction_10765291": { "compartment": "compartment_70101", "id": "reaction_10765291", "reactome": "R-SCE-114684", "name": "Phosphorylation of Syntaxin-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765281", "species_113592" ], "products": [ "species_29370", "species_10765289" ], "modifiers": [ [ "species_10765256", "catalyst" ] ], "additional_components": [ "P32867", "YPL232W", "P39926", "YMR183C", "P32867", "YPL232W", "P39926", "YMR183C", "species_33625", "P24583", "YBL105C", "species_74016", "species_6797635" ] }, "reaction_10770963": { "compartment": "compartment_876", "id": "reaction_10770963", "reactome": "R-SCE-481009", "name": "Exocytosis of platelet dense granule content", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770957" ], "products": [ "species_10770961" ], "modifiers": [], "additional_components": [ "species_29372", "species_74016", "species_113592", "species_29370", "species_111294", "CHEBI:15996", "species_111349", "P06101", "YDR168W", "species_109496", "species_209914", "species_29420", "species_29372", "species_74016", "species_113592", "species_29370", "species_29438", "species_111294", "P06101", "YDR168W", "species_109496", "species_209914" ] }, "reaction_10769661": { "compartment": "compartment_70101", "id": "reaction_10769661", "reactome": "R-SCE-425861", "name": "Activation of Protein Kinase C novel isoforms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767110", "species_114519" ], "products": [ "species_10769659" ], "modifiers": [], "additional_components": [ "YBL105C", "P24583", "YBL105C", "species_6797635" ] }, "reaction_10770980": { "compartment": "compartment_876", "id": "reaction_10770980", "reactome": "R-SCE-481044", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770972" ], "products": [ "species_10770978" ], "modifiers": [], "additional_components": [ "P38626", "YIL043C", "P53858", "YNL233W", "P38626", "YIL043C", "P53858", "YNL233W" ] }, "reaction_10774272": { "compartment": "compartment_70101", "id": "reaction_10774272", "reactome": "R-SCE-2316429", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767662", "species_179838" ], "products": [ "species_10764515" ], "modifiers": [], "additional_components": [ "YOL100W", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10769967": { "compartment": "compartment_70101", "id": "reaction_10769967", "reactome": "R-SCE-428961", "name": "Phosphorylation of cPLA2 by MAPK p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10769964" ], "products": [ "species_29370", "species_10764905" ], "modifiers": [ [ "species_10766455", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "YLR113W" ] }, "reaction_10770950": { "compartment": "compartment_876", "id": "reaction_10770950", "reactome": "R-SCE-481007", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770940" ], "products": [ "species_10770948" ], "modifiers": [], "additional_components": [ "Q05541", "YDR288W", "Q04338", "YMR197C", "P38219", "YBR025C", "Q05541", "YDR288W", "Q04338", "YMR197C", "P38219", "YBR025C" ] }, "reaction_10781550": { "compartment": "compartment_876", "id": "reaction_10781550", "reactome": "R-SCE-5694462", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694509", "species_29356" ], "products": [ "species_70106", "species_76116", "species_422506" ], "modifiers": [ [ "species_10781547", "catalyst" ] ], "additional_components": [ "YBR204C" ] }, "reaction_10769989": { "compartment": "compartment_114584", "id": "reaction_10769989", "reactome": "R-SCE-429157", "name": "ABCC4 accumulation of dense granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29372", "species_114565" ], "modifiers": [ [ "species_10769986", "catalyst" ] ], "additional_components": [ "YKL209C" ] }, "reaction_10770278": { "compartment": "compartment_70101", "id": "reaction_10770278", "reactome": "R-SCE-442749", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10770270" ], "products": [ "species_113582", "species_10770275" ], "modifiers": [ [ "species_10770270", "catalyst" ] ], "additional_components": [ "P06787", "YBR109C", "P43637", "YGL179C", "species_74016", "P06787", "YBR109C", "P43637", "YGL179C", "species_74016", "P06787", "YBR109C", "P43637", "YGL179C", "species_74016" ] }, "reaction_10789297": { "compartment": "compartment_70101", "id": "reaction_10789297", "reactome": "R-SCE-9748957", "name": "GMPS dimer transforms 6TXMP to 6TGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29356", "species_9748959" ], "products": [ "species_70106", "species_9748970", "species_29404", "species_111294", "species_76577" ], "modifiers": [ [ "species_10789294", "catalyst" ] ], "additional_components": [ "P38625", "YMR217W" ] }, "reaction_10789292": { "compartment": "compartment_70101", "id": "reaction_10789292", "reactome": "R-SCE-9748949", "name": "GUK1 phosphorylates 6TGMP to 6TGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9748970", "species_113592" ], "products": [ "species_29370", "species_9748960" ], "modifiers": [ [ "species_10763306", "catalyst" ] ], "additional_components": [ "YDR454C" ] }, "reaction_10766344": { "compartment": "compartment_17957", "id": "reaction_10766344", "reactome": "R-SCE-174931", "name": "UGTs transfer GlcA from UDP-GlcA to O-centre substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174384", "species_174911" ], "products": [ "species_158602", "species_174914" ], "modifiers": [ [ "species_10765441", "catalyst" ] ], "additional_components": [ "CHEBI:16580", "CHEBI:34665", "CHEBI:15882", "species_9749790", "CHEBI:46195", "CHEBI:32649", "species_158604", "CHEBI:65137", "CHEBI:176976", "CHEBI:64681", "YLR189C" ] }, "reaction_10789324": { "compartment": "compartment_70101", "id": "reaction_10789324", "reactome": "R-SCE-9751024", "name": "SLC29A1,2 transport 6MP from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9751015" ], "products": [ "species_9748998" ], "modifiers": [ [ "species_10764480", "catalyst" ] ], "additional_components": [ "YAL022C" ] }, "reaction_10789290": { "compartment": "compartment_70101", "id": "reaction_10789290", "reactome": "R-SCE-9748945", "name": "IMPDH tetramers dehydrogenate 6TIMP to 6TXMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9748992", "species_29360", "species_29356" ], "products": [ "species_73473", "species_70106", "species_9748959" ], "modifiers": [ [ "species_10763342", "catalyst" ] ], "additional_components": [ "P38697", "YHR216W", "P50095", "YLR432W", "P50094", "YML056C" ] }, "reaction_10789337": { "compartment": "compartment_70101", "id": "reaction_10789337", "reactome": "R-SCE-9753284", "name": "ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9753629", "species_29356" ], "products": [ "species_29370", "species_9753624", "species_29372" ], "modifiers": [ [ "species_10789334", "catalyst" ] ], "additional_components": [ "CHEBI:133438", "species_9753653", "CHEBI:133066", "CHEBI:133435", "P39109", "YDR135C", "P12866", "YKL209C" ] }, "reaction_10789314": { "compartment": "compartment_17957", "id": "reaction_10789314", "reactome": "R-SCE-9749977", "name": "UGT1A6 glucuronates ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9749790", "species_174384" ], "products": [ "species_158602", "species_9749997" ], "modifiers": [ [ "species_10765443", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10789299": { "compartment": "compartment_70101", "id": "reaction_10789299", "reactome": "R-SCE-9748963", "name": "GUK1 phosphorylates 6TdGMP to 6TdGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9749031", "species_113592" ], "products": [ "species_29370", "species_9749033" ], "modifiers": [ [ "species_10763306", "catalyst" ] ], "additional_components": [ "YDR454C" ] }, "reaction_10789332": { "compartment": "compartment_70101", "id": "reaction_10789332", "reactome": "R-SCE-9753283", "name": "ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_9753559" ], "products": [ "species_29370", "species_9753562", "species_29372" ], "modifiers": [ [ "species_10789329", "catalyst" ] ], "additional_components": [ "CHEBI:32635", "species_158604", "CHEBI:32636", "CHEBI:32635", "P53049", "YGR281W", "P12866", "YKL209C" ] }, "reaction_10789327": { "compartment": "compartment_70101", "id": "reaction_10789327", "reactome": "R-SCE-9753278", "name": "ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_9753559" ], "products": [ "species_29370", "species_9753562", "species_29372" ], "modifiers": [ [ "species_10772886", "catalyst" ] ], "additional_components": [ "CHEBI:32635", "species_158604", "CHEBI:32636", "CHEBI:32635", "P14772", "YLL015W", "P39109", "YDR135C", "P32386", "YLL048C", "P38735", "YHL035C" ] }, "reaction_10789339": { "compartment": "compartment_70101", "id": "reaction_10789339", "reactome": "R-SCE-9753632", "name": "CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9753680", "species_29356" ], "products": [ "species_9753653", "species_29424" ], "modifiers": [ [ "species_10772689", "catalyst" ] ], "additional_components": [ "species_113527", "P43616", "YFR044C" ] }, "reaction_10765448": { "compartment": "compartment_70101", "id": "reaction_10765448", "reactome": "R-SCE-158546", "name": "UGTs glucuronate APAP to APAP-GlcA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158601", "species_9677362" ], "products": [ "species_110096", "species_158604" ], "modifiers": [ [ "species_10765441", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10789301": { "compartment": "compartment_70101", "id": "reaction_10789301", "reactome": "R-SCE-9748969", "name": "NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9749033" ], "products": [ "species_29370", "species_9749032" ], "modifiers": [ [ "species_10770987", "catalyst" ] ], "additional_components": [ "P36010", "YKL067W" ] }, "reaction_10789303": { "compartment": "compartment_70101", "id": "reaction_10789303", "reactome": "R-SCE-9748999", "name": "NME1:2 hexamer phosphorylates 6TGDP to 6TGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9748960" ], "products": [ "species_29370", "species_9748947" ], "modifiers": [ [ "species_10770987", "catalyst" ] ], "additional_components": [ "P36010", "YKL067W" ] }, "reaction_10789322": { "compartment": "compartment_70101", "id": "reaction_10789322", "reactome": "R-SCE-9750656", "name": "ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9750692", "species_113592", "species_29356" ], "products": [ "species_29370", "species_9750678", "species_29372" ], "modifiers": [ [ "species_10789319", "catalyst" ] ], "additional_components": [ "CHEBI:9008", "CHEBI:58044", "CHEBI:88742", "CHEBI:176976", "CHEBI:36654", "species_9749997", "CHEBI:9008", "CHEBI:58044", "CHEBI:88742", "CHEBI:176976", "CHEBI:36654", "species_9749997", "P14772", "YLL015W", "P39109", "YDR135C", "P32386", "YLL048C", "P38735", "YHL035C", "P53049", "YGR281W" ] }, "reaction_10789317": { "compartment": "compartment_70101", "id": "reaction_10789317", "reactome": "R-SCE-9750546", "name": "ABCC4 transports TPMP substrates from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9750587", "species_113592", "species_29356" ], "products": [ "species_29370", "species_9750548", "species_29372" ], "modifiers": [ [ "species_10772888", "catalyst" ] ], "additional_components": [ "species_9748992", "species_9748970", "pubchem.compound:3037883", "CHEBI:80613", "pubchem.compound:3037883", "CHEBI:2332", "YKL209C" ] }, "reaction_10789341": { "compartment": "compartment_876", "id": "reaction_10789341", "reactome": "R-SCE-9753634", "name": "GGT dimers hydrolyse APAP-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9753685", "species_29356" ], "products": [ "species_9753680", "species_29404" ], "modifiers": [ [ "species_10777790", "catalyst" ] ], "additional_components": [ "Q05902", "YLR299W" ] }, "reaction_10781056": { "compartment": "compartment_7660", "id": "reaction_10781056", "reactome": "R-SCE-5691001", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781053", "species_30555" ], "products": [ "species_10781051", "species_113541" ], "modifiers": [ [ "species_10781053", "catalyst" ] ], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W" ] }, "reaction_10779690": { "compartment": "compartment_7660", "id": "reaction_10779690", "reactome": "R-SCE-5689861", "name": "Recruitment of XPA and release of CAK ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779684", "species_10779650" ], "products": [ "species_10763257", "species_10779688" ], "modifiers": [], "additional_components": [ "Q08273", "YOL133W", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "P05759", "RPS31", "Q02939", "YPL122C", "P32628", "YEL037C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q06665", "YDR314C", "P06839", "RAD3", "YMR201C", "Q03290", "YDR460W", "P37366", "YPR025C", "P06242", "YDL108W", "Q08273", "YOL133W", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P28519", "YMR201C", "P32776", "YDR311W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q12004", "YPR056W", "P05759", "RPS31", "Q02939", "YPL122C", "P32628", "YEL037C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q06665", "YDR314C", "P06839", "RAD3" ] }, "reaction_10766961": { "compartment": "compartment_70101", "id": "reaction_10766961", "reactome": "R-SCE-196773", "name": "COASY phosphorylates DP-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196778" ], "products": [ "species_76194", "species_29370" ], "modifiers": [ [ "species_10766945", "catalyst" ] ], "additional_components": [ "YGR277C" ] }, "reaction_10766940": { "compartment": "compartment_70101", "id": "reaction_10766940", "reactome": "R-SCE-196753", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111707", "species_196786" ], "products": [ "species_196834", "species_111294", "species_76577" ], "modifiers": [ [ "species_10766937", "catalyst" ] ], "additional_components": [ "P40506", "YIL083C" ] }, "reaction_10766948": { "compartment": "compartment_70101", "id": "reaction_10766948", "reactome": "R-SCE-196754", "name": "COASY transfers an adenylyl group from ATP to PPANT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196767", "species_113592" ], "products": [ "species_196778", "species_111294" ], "modifiers": [ [ "species_10766945", "catalyst" ] ], "additional_components": [ "YGR277C" ] }, "reaction_10767291": { "compartment": "compartment_70616", "id": "reaction_10767291", "reactome": "R-SCE-199216", "name": "SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194" ], "products": [ "species_29374" ], "modifiers": [ [ "species_10767288", "catalyst" ] ], "additional_components": [ "YHR002W" ] }, "reaction_10766971": { "compartment": "compartment_70101", "id": "reaction_10766971", "reactome": "R-SCE-196840", "name": "3xPPCDC:3FMN decarboxylates PPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196834" ], "products": [ "species_196767", "species_113528" ], "modifiers": [ [ "species_10766968", "catalyst" ] ], "additional_components": [ "P36076", "YKL088W", "species_73524" ] }, "reaction_10779496": { "compartment": "compartment_7660", "id": "reaction_10779496", "reactome": "R-SCE-5686430", "name": "MUS81 binds EME1, EME2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779488", "species_10779481" ], "products": [ "species_10779494" ], "modifiers": [], "additional_components": [ "YDR386W", "YBR098W", "P38257", "YBR098W", "Q04149", "YDR386W" ] }, "reaction_10761487": { "compartment": "compartment_70101", "id": "reaction_10761487", "reactome": "R-SCE-70581", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76213", "species_29404" ], "products": [ "species_29448", "species_29406" ], "modifiers": [ [ "species_10761484", "catalyst" ] ], "additional_components": [ "P23542", "YLR027C" ] }, "reaction_10761500": { "compartment": "compartment_5460", "id": "reaction_10761500", "reactome": "R-SCE-70596", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113553" ], "products": [ "species_113552", "species_113587" ], "modifiers": [ [ "species_10761497", "catalyst" ] ], "additional_components": [ "Q01802", "YKL106W" ] }, "reaction_10761517": { "compartment": "compartment_70101", "id": "reaction_10761517", "reactome": "R-SCE-70599", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29448", "species_113592", "species_29356" ], "products": [ "species_29404", "species_29642", "species_111294", "species_76577" ], "modifiers": [ [ "species_10761514", "catalyst" ] ], "additional_components": [ "P49090", "YGR124W", "P49089", "YPR145W" ] }, "reaction_10781277": { "compartment": "compartment_876", "id": "reaction_10781277", "reactome": "R-SCE-5693783", "name": "NAALADases hydrolyse NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693762" ], "products": [ "species_29404", "species_5693772" ], "modifiers": [ [ "species_10781274", "catalyst" ] ], "additional_components": [ "Q08693", "YOR256C", "P47161", "YJR126C", "Q08919", "YPL176C" ] }, "reaction_10768525": { "compartment": "compartment_70101", "id": "reaction_10768525", "reactome": "R-SCE-372448", "name": "SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113553" ], "products": [ "species_29448", "species_113552" ], "modifiers": [ [ "species_10768520", "catalyst" ] ], "additional_components": [ "YPR021C" ] }, "reaction_10761489": { "compartment": "compartment_70101", "id": "reaction_10761489", "reactome": "R-SCE-70592", "name": "PXLP-K259-GOT1 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29448", "species_29406" ], "products": [ "species_29404", "species_76213" ], "modifiers": [ [ "species_10761484", "catalyst" ] ], "additional_components": [ "P23542", "YLR027C" ] }, "reaction_10782374": { "compartment": "compartment_7660", "id": "reaction_10782374", "reactome": "R-SCE-6791222", "name": "21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782324" ], "products": [ "species_10782340" ], "modifiers": [ [ "species_10782371", "catalyst" ], [ "species_10782359", "catalyst" ], [ "species_10782077", "catalyst" ], [ "species_10782345", "catalyst" ] ], "additional_components": [ "Q04177", "UTP5", "P53941", "IMP4", "Q02354", "UTP6", "P25368", "RRP7", "Q04217", "ECM16", "P06367", "RPS14A", "P25443", "RPS2", "P40498", "UTP25", "Q05498", "FCF1", "P35194", "UTP20", "Q99207", "NOP14", "P40362", "UTP18", "P34247", "UTP11", "Q04305", "UTP15", "Q06512", "NOC4", "P40055", "UTP7", "Q12220", "DIP2", "P33750", "SOF1", "Q08965", "BMS1", "P39990", "SNU13", "P47083", "MPP10", "Q06287", "EMG1", "P38719", "DBP8", "Q05022", "RRP5", "P45818", "ROK1", "P38712", "RRP3", "P05755", "RPS9B", "Q02931", "NAN1", "P42945", "UTP10", "Q08096", "RCL1", "Q12136", "SAS10", "Q06506", "RRP9", "P0CX37", "RPS6A", "Q06679", "UTP4", "P26786", "RPS7A", "P25586", "KRR1", "P15646", "NOP1", "Q05946", "UTP13", "Q12460", "NOP56", "Q06078", "UTP21", "P25635", "PWP2", "P53254", "UTP22", "Q04500", "UTP14", "P32899", "IMP3", "Q12481", "RRP36", "Q12499", "NOP58", "P0CX38", "RPS6B", "P39516", "RPS14B", "Q04177", "UTP5", "P53941", "IMP4", "Q02354", "UTP6", "P25368", "RRP7", "Q04217", "ECM16", "P06367", "RPS14A", "P25443", "RPS2", "P40498", "UTP25", "Q05498", "FCF1", "P35194", "UTP20", "Q99207", "NOP14", "P40362", "UTP18", "P34247", "UTP11", "Q04305", "UTP15", "Q06512", "NOC4", "P40055", "UTP7", "Q12220", "DIP2", "P33750", "SOF1", "Q08965", "BMS1", "P39990", "SNU13", "P47083", "MPP10", "Q06287", "EMG1", "P38719", "DBP8", "Q05022", "RRP5", "P45818", "ROK1", "P38712", "RRP3", "P05755", "RPS9B", "Q02931", "NAN1", "P42945", "UTP10", "Q08096", "RCL1", "Q12136", "SAS10", "Q06506", "RRP9", "P0CX37", "RPS6A", "Q06679", "UTP4", "P26786", "RPS7A", "P25586", "KRR1", "P15646", "NOP1", "Q05946", "UTP13", "Q12460", "NOP56", "Q06078", "UTP21", "P25635", "PWP2", "P53254", "UTP22", "Q04500", "UTP14", "P32899", "IMP3", "Q12481", "RRP36", "Q12499", "NOP58", "P0CX38", "RPS6B", "P39516", "RPS14B", "P38801", "YHR081W", "Q12149", "YOR001W", "P53859", "CSL4", "Q08285", "RRP40", "P53256", "RRP46", "Q12277", "RRP42", "P48240", "MTR3", "P38792", "RRP4", "P46948", "SKI6", "P47047", "YJL050W", "Q05636", "RRP45", "P25359", "RRP43", "YJL050W", "YOR001W" ] }, "reaction_10782565": { "compartment": "compartment_70101", "id": "reaction_10782565", "reactome": "R-SCE-6791223", "name": "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782539", "species_10782537" ], "products": [ "species_10782549", "species_10782541", "species_10762573", "species_10782555", "species_10782551", "species_10782539", "species_10782553", "species_10782557", "species_10782547", "species_10782545", "species_10782543" ], "modifiers": [ [ "species_10782545", "catalyst" ], [ "species_10782555", "catalyst" ], [ "species_10782563", "catalyst" ], [ "species_10782557", "catalyst" ] ], "additional_components": [ "YOR119C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "Q12196", "YOR119C", "P0CH08", "RPL40A", "P38333", "YBR247C", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "P34078", "YKL143W", "P0CX37", "RPS6A", "P38711", "RPS27B", "P38786", "YHR062C", "P0CX30", "RPS23B", "P40571", "YIR015W", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P50109", "YML017W", "P07280", "RPS19A", "P0CX39", "RPS8A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P0CX32", "RPS24B", "P40160", "YNL207W", "Q99216", "YOR145C", "P0CX35", "RPS4A", "P23248", "RPS1B", "P0CX47", "RPS11A", "P0CX56", "RPS18B", "P26786", "RPS7A", "Q01855", "RPS15", "P29295", "YPL204W", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "Q08444", "YOR056C", "P0CX40", "RPS8B", "P14127", "RPS17B", "Q07381", "YDL060W", "YNL207W", "YBR247C", "P0CX52", "RPS16B", "P35997", "RPS27A", "Q08745", "RPS10A", "P46784", "RPS10B", "P25443", "RPS2", "P06367", "RPS14A", "P0CX55", "RPS18A", "P0CX32", "RPS24B", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX35", "RPS4A", "P23248", "RPS1B", "P0CH08", "RPL40A", "P0CX47", "RPS11A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "P0CX37", "RPS6A", "P0CX56", "RPS18B", "P38711", "RPS27B", "P26786", "RPS7A", "P0CX30", "RPS23B", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P07281", "RPS19B", "P05759", "RPS31", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "YPL204W", "YDL060W", "YOR119C", "YOR119C", "YPL204W", "YOR145C", "YOR056C", "YKL143W", "YOR056C", "YPL204W", "YCR047C", "YPL204W" ] }, "reaction_10782116": { "compartment": "compartment_7660", "id": "reaction_10782116", "reactome": "R-SCE-6791219", "name": "32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782100" ], "products": [ "species_10782067" ], "modifiers": [ [ "species_10782063", "catalyst" ], [ "species_10782098", "catalyst" ], [ "species_10782114", "catalyst" ], [ "species_10782058", "catalyst" ] ], "additional_components": [ "Q12024", "YOR272W", "P38883", "YHR197W", "Q07845", "YLL035W", "P38803", "YHR085W", "P36146", "YKR063C", "Q02724", "YPL020C", "P53877", "YNL182C", "P53261", "YGR103W", "Q04660", "YMR049C", "P38883", "YHR197W", "Q07845", "YLL035W", "P38803", "YHR085W", "P36146", "YKR063C", "Q02724", "YPL020C", "P53877", "YNL182C", "YLL035W", "Q12024", "YOR272W", "P53261", "YGR103W", "Q04660", "YMR049C", "P36049", "YKL172W", "P40010", "YER006W", "P53261", "YGR103W", "YKR063C" ] }, "reaction_10767666": { "compartment": "compartment_70101", "id": "reaction_10767666", "reactome": "R-SCE-202164", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767662", "species_202277" ], "products": [ "species_10767664" ], "modifiers": [], "additional_components": [ "YOL100W", "species_202247", "species_179838", "species_202247", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10767681": { "compartment": "compartment_876", "id": "reaction_10767681", "reactome": "R-SCE-202222", "name": "Phosphorylation of PKC theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767671", "species_113592" ], "products": [ "species_29370", "species_10767678" ], "modifiers": [ [ "species_10767664", "catalyst" ] ], "additional_components": [ "species_112275", "P24583", "YBL105C", "species_112275", "P24583", "YBL105C", "species_202247", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10767319": { "compartment": "compartment_70101", "id": "reaction_10767319", "reactome": "R-SCE-199456", "name": "PTEN dephosphorylates PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_29356" ], "products": [ "species_29372", "species_179856" ], "modifiers": [ [ "species_10767316", "catalyst" ] ], "additional_components": [ "YNL128W" ] }, "reaction_10767687": { "compartment": "compartment_70101", "id": "reaction_10767687", "reactome": "R-SCE-202328", "name": "Translocation of PKC theta to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767566", "species_112275" ], "products": [ "species_10767685" ], "modifiers": [], "additional_components": [ "YBL105C", "species_112275", "P24583", "YBL105C" ] }, "reaction_10764508": { "compartment": "compartment_7660", "id": "reaction_10764508", "reactome": "R-SCE-109639", "name": "Formation of the closed pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763293", "species_10763806" ], "products": [ "species_10764070" ], "modifiers": [], "additional_components": [ "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "P32774", "YKL058W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10764504": { "compartment": "compartment_7660", "id": "reaction_10764504", "reactome": "R-SCE-109637", "name": "Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763800", "species_10763417", "species_10763422" ], "products": [ "species_10763802" ], "modifiers": [], "additional_components": [ "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "P32774", "YKL058W", "P32773", "YOR194C", "YPR086W", "Q04226", "YML015C", "Q12030", "YDR167W", "P23255", "YCR042C", "Q05021", "YMR227C", "P53040", "YGL112C", "P32774", "YKL058W", "P29055", "YPR086W", "Q03761", "YDR145W", "P13393", "SPT15", "Q05027", "YMR236W", "P38129", "YBR198C", "P50105", "YMR005W", "P46677", "YGR274C", "P11747", "YML098W", "P32773", "YOR194C" ] }, "reaction_10763808": { "compartment": "compartment_7660", "id": "reaction_10763808", "reactome": "R-SCE-75095", "name": "Binding of TFIIE to the growing preinitiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763503", "species_10763804" ], "products": [ "species_10763806" ], "modifiers": [], "additional_components": [ "P36100", "YKL028W", "P36145", "YKR062W", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "P32774", "YKL058W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P11747", "YML098W", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "P32774", "YKL058W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W" ] }, "reaction_10764502": { "compartment": "compartment_7660", "id": "reaction_10764502", "reactome": "R-SCE-109636", "name": "Recognition and Binding of Core Promoter Elements by TFIID", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109627", "species_10763491" ], "products": [ "species_10763800" ], "modifiers": [], "additional_components": [ "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15" ] }, "reaction_10764506": { "compartment": "compartment_7660", "id": "reaction_10764506", "reactome": "R-SCE-109638", "name": "Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762312", "species_10763802" ], "products": [ "species_10763804" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "Q04226", "YML015C", "Q12030", "YDR167W", "P23255", "YCR042C", "Q05021", "YMR227C", "P53040", "YGL112C", "P32774", "YKL058W", "P29055", "YPR086W", "Q03761", "YDR145W", "P13393", "SPT15", "Q05027", "YMR236W", "P38129", "YBR198C", "P50105", "YMR005W", "P46677", "YGR274C", "P11747", "YML098W", "P32773", "YOR194C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "P32774", "YKL058W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P11747", "YML098W" ] }, "reaction_10769195": { "compartment": "compartment_876", "id": "reaction_10769195", "reactome": "R-SCE-399998", "name": "Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10769192", "catalyst" ] ], "additional_components": [ "P32383", "YPL268W", "species_29438", "P10823", "YER020W" ] }, "reaction_10772682": { "compartment": "compartment_70101", "id": "reaction_10772682", "reactome": "R-SCE-1237160", "name": "MTA is cleaved and phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353106", "species_29372" ], "products": [ "species_83951", "species_1237165" ], "modifiers": [ [ "species_10772679", "catalyst" ] ], "additional_components": [ "Q07938", "YLR017W" ] }, "reaction_10772662": { "compartment": "compartment_70101", "id": "reaction_10772662", "reactome": "R-SCE-1237119", "name": "Acireductone is oxidized to MOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237155", "species_29368" ], "products": [ "species_1237122", "species_29460" ], "modifiers": [ [ "species_10772659", "catalyst" ] ], "additional_components": [ "species_111793", "Q03677", "YMR009W" ] }, "reaction_10772652": { "compartment": "compartment_70101", "id": "reaction_10772652", "reactome": "R-SCE-1237096", "name": "Methylthio-ribose-P = Methylthio-ribulose-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237165" ], "products": [ "species_1237107" ], "modifiers": [ [ "species_10772649", "catalyst" ] ], "additional_components": [ "YPR118W" ] }, "reaction_10772672": { "compartment": "compartment_70101", "id": "reaction_10772672", "reactome": "R-SCE-1237129", "name": "Acireductone is created", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237176", "species_29356" ], "products": [ "species_70106", "species_1237155", "species_29372" ], "modifiers": [ [ "species_10772669", "catalyst" ] ], "additional_components": [ "P32626", "YEL038W", "species_109496" ] }, "reaction_10787565": { "compartment": "compartment_70101", "id": "reaction_10787565", "reactome": "R-SCE-8951727", "name": "cAMP binds PKA tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764953", "species_30389" ], "products": [ "species_10764955" ], "modifiers": [], "additional_components": [ "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "species_30389" ] }, "reaction_10788654": { "compartment": "compartment_70101", "id": "reaction_10788654", "reactome": "R-SCE-9619355", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10788647" ], "products": [ "species_29370", "species_10788651" ], "modifiers": [ [ "species_10788647", "catalyst" ] ], "additional_components": [ "P06787", "YBR109C", "P43637", "YGL179C", "species_74016", "P06787", "YBR109C", "P43637", "YGL179C", "species_74016", "P06787", "YBR109C", "P43637", "YGL179C", "species_74016" ] }, "reaction_10788663": { "compartment": "compartment_70101", "id": "reaction_10788663", "reactome": "R-SCE-9619376", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767628", "species_10788659" ], "products": [ "species_10788661" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_74016", "YLR248W", "P06787", "YBR109C", "P38623", "YLR248W", "species_74016" ] }, "reaction_10764959": { "compartment": "compartment_70101", "id": "reaction_10764959", "reactome": "R-SCE-111925", "name": "cAMP induces dissociation of inactive PKA tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764955" ], "products": [ "species_10764957", "species_10764951" ], "modifiers": [], "additional_components": [ "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "species_30389", "P07278", "YIL033C", "species_30389", "P05986", "YKL166C", "P06245", "YPL203W", "P06244", "YJL164C" ] }, "reaction_10789248": { "compartment": "compartment_12045", "id": "reaction_10789248", "reactome": "R-SCE-9714361", "name": "RHOC activates endoplasmic reticulum effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789244", "species_10789214" ], "products": [ "species_10789246" ], "modifiers": [], "additional_components": [ "Q01590", "YLR026C", "Q12396", "YLR080W", "P43555", "YFL048C", "P36137", "YKR044W", "P40075", "YER120W", "P32462", "YNL280C", "Q6Q595", "YBL091C-A", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q01590", "YLR026C", "Q12396", "YLR080W", "Q00246", "YKR055W", "P06781", "YNL090W", "P43555", "YFL048C", "P36137", "YKR044W", "P06780", "YPR165W", "P40075", "YER120W", "species_29438", "P32462", "YNL280C", "Q6Q595", "YBL091C-A" ] }, "reaction_10788156": { "compartment": "compartment_876", "id": "reaction_10788156", "reactome": "R-SCE-9013437", "name": "RHOD GAPs stimulate RHOD GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136", "species_29356" ], "products": [ "species_29372", "species_10788124" ], "modifiers": [ [ "species_10788153", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "P39960", "YER155C", "Q06407", "YDR379W", "P38339", "YBR260C", "P32873", "YPL115C", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10789129": { "compartment": "compartment_17906", "id": "reaction_10789129", "reactome": "R-SCE-9693214", "name": "RHOD binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788063", "species_10789123" ], "products": [ "species_10789127" ], "modifiers": [], "additional_components": [ "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "P48562", "YNL298W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "Q03497", "YHL007C", "P06780", "YPR165W", "species_29438", "Q12469", "YOL113W" ] }, "reaction_10788047": { "compartment": "compartment_70101", "id": "reaction_10788047", "reactome": "R-SCE-9013108", "name": "GDIs block activation of RHOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787983", "species_10788033" ], "products": [ "species_10788045" ], "modifiers": [], "additional_components": [ "YDL135C", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29420", "Q12434", "YDL135C", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W" ] }, "reaction_10789250": { "compartment": "compartment_876", "id": "reaction_10789250", "reactome": "R-SCE-9714363", "name": "RHOC translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778611" ], "products": [ "species_10789214" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10788248": { "compartment": "compartment_876", "id": "reaction_10788248", "reactome": "R-SCE-9018768", "name": "RHOU auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10788245" ], "products": [ "species_10788230", "species_29420" ], "modifiers": [ [ "species_10788245", "catalyst" ] ], "additional_components": [ "species_29420", "P19073", "YLR229C", "species_29438", "P19073", "YLR229C", "species_29420", "P19073", "YLR229C" ] }, "reaction_10788109": { "compartment": "compartment_876", "id": "reaction_10788109", "reactome": "R-SCE-9013161", "name": "CDC42 GAPs stimulate CDC42 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10768894" ], "products": [ "species_10788091", "species_29372" ], "modifiers": [ [ "species_10788106", "catalyst" ] ], "additional_components": [ "species_29438", "P19073", "YLR229C", "species_29420", "P19073", "YLR229C", "P39960", "YER155C", "Q12128", "YOR134W", "Q06407", "YDR379W", "P38339", "YBR260C", "P32873", "YPL115C", "P17121", "YDR389W", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10789177": { "compartment": "compartment_70101", "id": "reaction_10789177", "reactome": "R-SCE-9696267", "name": "RND3 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10789173" ], "products": [ "species_10789175" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10788020": { "compartment": "compartment_70101", "id": "reaction_10788020", "reactome": "R-SCE-9013021", "name": "GDIs block activation of RHOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788014", "species_10788012" ], "products": [ "species_10788018" ], "modifiers": [], "additional_components": [ "YDL135C", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29420", "Q00245", "YIL118W", "Q12434", "YDL135C", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W" ] }, "reaction_10788031": { "compartment": "compartment_70101", "id": "reaction_10788031", "reactome": "R-SCE-9013024", "name": "RHOB binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788027", "species_10788022" ], "products": [ "species_10788029" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "Q08693", "YOR256C", "Q12280", "YPL242C", "P24583", "YBL105C", "P33328", "YOR327C", "P47161", "YJR126C", "Q04359", "YMR017W", "Q08919", "YPL176C", "P32525", "YJL201W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "P40357", "YGR009C", "Q08693", "YOR256C", "Q00246", "YKR055W", "P06781", "YNL090W", "P33328", "YOR327C", "P47161", "YJR126C", "Q04359", "YMR017W", "species_29438", "Q08919", "YPL176C", "P32525", "YJL201W", "Q00245", "YIL118W", "Q12280", "YPL242C", "P24583", "YBL105C", "P06780", "YPR165W" ] }, "reaction_10788295": { "compartment": "compartment_876", "id": "reaction_10788295", "reactome": "R-SCE-9018806", "name": "RAC3 GAPs stimulate RAC3 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788278", "species_29356" ], "products": [ "species_10788276", "species_29372" ], "modifiers": [ [ "species_10788292", "catalyst" ] ], "additional_components": [ "P53879", "YNL180C", "species_29438", "species_29420", "P53879", "YNL180C", "P39960", "YER155C", "Q06407", "YDR379W", "P38339", "YBR260C", "Q08227", "YOL065C", "P32873", "YPL115C", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10788305": { "compartment": "compartment_876", "id": "reaction_10788305", "reactome": "R-SCE-9018807", "name": "RAC3 GDIs block activation of RAC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788276", "species_10788297" ], "products": [ "species_10788303" ], "modifiers": [], "additional_components": [ "species_29420", "P53879", "YNL180C", "Q12434", "YDL135C", "species_29420", "P53879", "YNL180C", "Q12434", "YDL135C" ] }, "reaction_10789282": { "compartment": "compartment_876", "id": "reaction_10789282", "reactome": "R-SCE-9726862", "name": "Phosphorylated RHOU translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789276" ], "products": [ "species_10789280" ], "modifiers": [], "additional_components": [ "species_29420", "P19073", "YLR229C", "species_29420", "P19073", "YLR229C" ] }, "reaction_10788265": { "compartment": "compartment_876", "id": "reaction_10788265", "reactome": "R-SCE-9018794", "name": "RHOV binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788252", "species_10788261" ], "products": [ "species_10788263" ], "modifiers": [], "additional_components": [ "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "P39960", "YER155C", "Q03497", "YHL007C", "Q12280", "YPL242C", "Q06407", "YDR379W", "Q08924", "YPL183C", "P38339", "YBR260C", "P22137", "YGL206C", "P32873", "YPL115C", "Q12469", "YOL113W", "P17536", "YNL079C", "P19073", "YLR229C", "P39083", "YOR127W", "P48562", "YNL298W", "P39960", "YER155C", "P38339", "YBR260C", "species_29438", "P19073", "YLR229C", "Q03497", "YHL007C", "Q12280", "YPL242C", "Q06407", "YDR379W", "Q08924", "YPL183C", "P22137", "YGL206C", "P32873", "YPL115C", "Q12469", "YOL113W", "P17536", "YNL079C", "P39083", "YOR127W" ] }, "reaction_10788184": { "compartment": "compartment_876", "id": "reaction_10788184", "reactome": "R-SCE-9013438", "name": "RHOD binds effectors at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788168", "species_10788180" ], "products": [ "species_10788182" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "P40578", "YIR033W", "P35210", "YKL020C", "P32462", "YNL280C", "Q12091", "YPL170W", "P40578", "YIR033W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P35210", "YKL020C", "P06780", "YPR165W", "P32462", "YNL280C", "species_29438", "Q12091", "YPL170W" ] }, "reaction_10787825": { "compartment": "compartment_70101", "id": "reaction_10787825", "reactome": "R-SCE-8981637", "name": "RHOA GAPs stimulate RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10765231" ], "products": [ "species_10765229", "species_29372" ], "modifiers": [ [ "species_10787822", "catalyst" ] ], "additional_components": [ "P06780", "YPR165W", "species_29438", "species_29420", "P06780", "YPR165W", "P39960", "YER155C", "Q12128", "YOR134W", "Q06407", "YDR379W", "P38339", "YBR260C", "P32873", "YPL115C", "P17121", "YDR389W", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10788139": { "compartment": "compartment_876", "id": "reaction_10788139", "reactome": "R-SCE-9013435", "name": "RHOD auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10788124" ], "products": [ "species_10788136", "species_29420" ], "modifiers": [ [ "species_10788124", "catalyst" ] ], "additional_components": [ "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W" ] }, "reaction_10789125": { "compartment": "compartment_876", "id": "reaction_10789125", "reactome": "R-SCE-9693207", "name": "RHOD translocates to the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136" ], "products": [ "species_10789123" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10789143": { "compartment": "compartment_876", "id": "reaction_10789143", "reactome": "R-SCE-9693243", "name": "RHOD translocates to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136" ], "products": [ "species_10789141" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10788102": { "compartment": "compartment_876", "id": "reaction_10788102", "reactome": "R-SCE-9013159", "name": "CDC42 GEFs activate CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10788091" ], "products": [ "species_29420", "species_10768894" ], "modifiers": [ [ "species_10788099", "catalyst" ] ], "additional_components": [ "species_29420", "P19073", "YLR229C", "species_29438", "P19073", "YLR229C", "P04821", "YLR310C", "Q05670", "YMR232W", "P34216", "YBL047C", "P07866", "YAL024C", "P25300", "YCR038C", "P10823", "YER020W" ] }, "reaction_10789145": { "compartment": "compartment_876", "id": "reaction_10789145", "reactome": "R-SCE-9693282", "name": "RHOF GAPs stimulate RHOF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789100", "species_29356" ], "products": [ "species_10789098", "species_29372" ], "modifiers": [ [ "species_10788153", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "P39960", "YER155C", "Q06407", "YDR379W", "P38339", "YBR260C", "P32873", "YPL115C", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10788269": { "compartment": "compartment_876", "id": "reaction_10788269", "reactome": "R-SCE-9018798", "name": "RHOV binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10788267" ], "products": [ "species_10788252", "species_29420" ], "modifiers": [], "additional_components": [ "species_29420", "P19073", "YLR229C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10787993": { "compartment": "compartment_876", "id": "reaction_10787993", "reactome": "R-SCE-9013006", "name": "RHOA:GTP translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765231" ], "products": [ "species_10787991" ], "modifiers": [], "additional_components": [ "P06780", "YPR165W", "species_29438", "P06780", "YPR165W", "species_29438" ] }, "reaction_10787743": { "compartment": "compartment_70101", "id": "reaction_10787743", "reactome": "R-SCE-8980691", "name": "RHOA GEFs activate RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10765229" ], "products": [ "species_10765231", "species_29420" ], "modifiers": [ [ "species_10787740", "catalyst" ] ], "additional_components": [ "species_29420", "P06780", "YPR165W", "P06780", "YPR165W", "species_29438", "P04821", "YLR310C", "Q06409", "YLR422W", "P07866", "YAL024C", "P25300", "YCR038C" ] }, "reaction_10789092": { "compartment": "compartment_876", "id": "reaction_10789092", "reactome": "R-SCE-9690494", "name": "RHOB translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788022" ], "products": [ "species_10778663" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10788010": { "compartment": "compartment_876", "id": "reaction_10788010", "reactome": "R-SCE-9013009", "name": "RHOA binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788006", "species_10765231" ], "products": [ "species_10788008" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "Q08693", "YOR256C", "P33328", "YOR327C", "P22213", "YDR189W", "P47161", "YJR126C", "Q12229", "YDL091C", "Q04359", "YMR017W", "Q08919", "YPL176C", "P32525", "YJL201W", "Q12280", "YPL242C", "P24583", "YBL105C", "P40513", "YIL070C", "P36126", "YKR031C", "Q04228", "YML013W", "P06780", "YPR165W", "species_29438", "P40357", "YGR009C", "Q08693", "YOR256C", "P33328", "YOR327C", "P22213", "YDR189W", "P47161", "YJR126C", "Q12229", "YDL091C", "Q04359", "YMR017W", "species_29438", "Q08919", "YPL176C", "P32525", "YJL201W", "Q12280", "YPL242C", "P24583", "YBL105C", "P06780", "YPR165W", "P40513", "YIL070C", "P36126", "YKR031C", "Q04228", "YML013W" ] }, "reaction_10788053": { "compartment": "compartment_876", "id": "reaction_10788053", "reactome": "R-SCE-9013110", "name": "RHOC binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778611", "species_10788049" ], "products": [ "species_10788051" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q08693", "YOR256C", "Q12280", "YPL242C", "P24583", "YBL105C", "P33328", "YOR327C", "P06780", "YPR165W", "P40513", "YIL070C", "P47161", "YJR126C", "Q08919", "YPL176C", "P32525", "YJL201W", "Q00245", "YIL118W", "Q08693", "YOR256C", "Q00246", "YKR055W", "P06781", "YNL090W", "Q12280", "YPL242C", "P24583", "YBL105C", "P33328", "YOR327C", "P06780", "YPR165W", "P40513", "YIL070C", "P47161", "YJR126C", "species_29438", "Q08919", "YPL176C", "P32525", "YJL201W" ] }, "reaction_10788186": { "compartment": "compartment_876", "id": "reaction_10788186", "reactome": "R-SCE-9013452", "name": "RHOD:GTP translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136" ], "products": [ "species_10788168" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10789194": { "compartment": "compartment_70101", "id": "reaction_10789194", "reactome": "R-SCE-9696271", "name": "RND1 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769249", "species_10789190" ], "products": [ "species_10789192" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q08693", "YOR256C", "P19158", "YOL081W", "Q08924", "YPL183C", "P01120", "YNL098C", "Q04458", "YMR110C", "P15705", "YOR027W", "P18963", "YBR140C", "P47161", "YJR126C", "Q08919", "YPL176C", "Q08693", "YOR256C", "Q00246", "YKR055W", "P06781", "YNL090W", "P01120", "YNL098C", "P15705", "YOR027W", "P18963", "YBR140C", "P47161", "YJR126C", "species_29438", "Q08919", "YPL176C", "Q00245", "YIL118W", "P19158", "YOL081W", "Q08924", "YPL183C", "P06780", "YPR165W", "Q04458", "YMR110C" ] }, "reaction_10788055": { "compartment": "compartment_876", "id": "reaction_10788055", "reactome": "R-SCE-9013111", "name": "RHOC GAPs stimulate RHOC GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778611", "species_29356" ], "products": [ "species_10788033", "species_29372" ], "modifiers": [ [ "species_10787796", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "YJL201W" ] }, "reaction_10789111": { "compartment": "compartment_70101", "id": "reaction_10789111", "reactome": "R-SCE-9693198", "name": "RHOD binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136", "species_10789107" ], "products": [ "species_10789109" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "P48562", "YNL298W", "Q03497", "YHL007C", "P13517", "YIL034C", "P33328", "YOR327C", "P15891", "YCR088W", "P32939", "YML001W", "Q12469", "YOL113W", "P32525", "YJL201W", "P48562", "YNL298W", "Q00245", "YIL118W", "Q03497", "YHL007C", "Q00246", "YKR055W", "P06781", "YNL090W", "P13517", "YIL034C", "P33328", "YOR327C", "P15891", "YCR088W", "P32939", "YML001W", "P06780", "YPR165W", "species_29438", "Q12469", "YOL113W", "P32525", "YJL201W" ] }, "reaction_10789196": { "compartment": "compartment_70101", "id": "reaction_10789196", "reactome": "R-SCE-9696274", "name": "RND1 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10769247" ], "products": [ "species_10769249" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10789103": { "compartment": "compartment_876", "id": "reaction_10789103", "reactome": "R-SCE-9693111", "name": "RHOF auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10789098" ], "products": [ "species_10789100", "species_29420" ], "modifiers": [ [ "species_10789098", "catalyst" ] ], "additional_components": [ "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W" ] }, "reaction_10787989": { "compartment": "compartment_70101", "id": "reaction_10787989", "reactome": "R-SCE-9012835", "name": "GDIs block activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787983", "species_10765229" ], "products": [ "species_10787987" ], "modifiers": [], "additional_components": [ "YDL135C", "species_29420", "P06780", "YPR165W", "species_29420", "Q12434", "YDL135C", "P06780", "YPR165W" ] }, "reaction_10789096": { "compartment": "compartment_876", "id": "reaction_10789096", "reactome": "R-SCE-9692800", "name": "CDC42 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768894" ], "products": [ "species_10789094" ], "modifiers": [], "additional_components": [ "species_29438", "P19073", "YLR229C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10788243": { "compartment": "compartment_876", "id": "reaction_10788243", "reactome": "R-SCE-9018766", "name": "RHOU binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788230", "species_10788239" ], "products": [ "species_10788241" ], "modifiers": [], "additional_components": [ "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "P53281", "YGR136W", "P39940", "YER125W", "Q03497", "YHL007C", "Q12280", "YPL242C", "P38753", "YHL002W", "Q08924", "YPL183C", "P34216", "YBL047C", "P39013", "YNL084C", "P22137", "YGL206C", "P32521", "YIR006C", "Q12469", "YOL113W", "P19073", "YLR229C", "P48562", "YNL298W", "P53281", "YGR136W", "P39940", "YER125W", "P38753", "YHL002W", "P34216", "YBL047C", "species_29438", "P19073", "YLR229C", "Q03497", "YHL007C", "Q12280", "YPL242C", "Q08924", "YPL183C", "P39013", "YNL084C", "P22137", "YGL206C", "P32521", "YIR006C", "Q12469", "YOL113W" ] }, "reaction_10788095": { "compartment": "compartment_876", "id": "reaction_10788095", "reactome": "R-SCE-9013158", "name": "CDC42 GDIs block activation of CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787983", "species_10788091" ], "products": [ "species_10788093" ], "modifiers": [], "additional_components": [ "YDL135C", "species_29420", "P19073", "YLR229C", "species_29420", "Q12434", "YDL135C", "P19073", "YLR229C" ] }, "reaction_10788025": { "compartment": "compartment_70101", "id": "reaction_10788025", "reactome": "R-SCE-9013022", "name": "RHOB GAPs stimulate RHOB GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10788022" ], "products": [ "species_10788012", "species_29372" ], "modifiers": [ [ "species_10787796", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "YJL201W" ] }, "reaction_10789198": { "compartment": "compartment_70101", "id": "reaction_10789198", "reactome": "R-SCE-9696275", "name": "RND2 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10789161" ], "products": [ "species_10789163" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10789256": { "compartment": "compartment_876", "id": "reaction_10789256", "reactome": "R-SCE-9714694", "name": "RAC3 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788278" ], "products": [ "species_10789254" ], "modifiers": [], "additional_components": [ "P53879", "YNL180C", "species_29438", "P53879", "YNL180C", "species_29438" ] }, "reaction_10764078": { "compartment": "compartment_7660", "id": "reaction_10764078", "reactome": "R-SCE-75866", "name": "Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764066" ], "products": [ "species_10764074" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q05027", "YMR236W", "species_6806881", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "P38129", "YBR198C", "Q02939", "YPL122C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32774", "YKL058W", "P32776", "YDR311W", "P13393", "SPT15", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10764086": { "compartment": "compartment_7660", "id": "reaction_10764086", "reactome": "R-SCE-75873", "name": "Addition of Nucleotides 5 through 9 on the growing Transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764080" ], "products": [ "species_10763503", "species_10763491", "species_113541", "species_10763417", "species_10764084" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P36100", "YKL028W", "P36145", "YKR062W", "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "P32774", "YKL058W", "P32773", "YOR194C", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764068": { "compartment": "compartment_7660", "id": "reaction_10764068", "reactome": "R-SCE-75861", "name": "NTP Binds Active Site of RNA Polymerase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764062" ], "products": [ "species_10764066" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q05027", "YMR236W", "species_6806881", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "P38129", "YBR198C", "Q02939", "YPL122C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32774", "YKL058W", "P32776", "YDR311W", "P13393", "SPT15", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10764035": { "compartment": "compartment_7660", "id": "reaction_10764035", "reactome": "R-SCE-75850", "name": "Addition of the third nucleotide on the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10763505" ], "products": [ "species_10764032", "species_113541" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764285": { "compartment": "compartment_7660", "id": "reaction_10764285", "reactome": "R-SCE-76576", "name": "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764084" ], "products": [ "species_10764283", "species_113541" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764082": { "compartment": "compartment_7660", "id": "reaction_10764082", "reactome": "R-SCE-75869", "name": "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764032" ], "products": [ "species_10764080", "species_113541", "species_10763422" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "YPR086W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10788639": { "compartment": "compartment_7660", "id": "reaction_10788639", "reactome": "R-SCE-9613497", "name": "Unwinding DNA for the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10763505" ], "products": [ "species_10763505", "species_113541" ], "modifiers": [ [ "species_10763293", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W" ] }, "reaction_10788637": { "compartment": "compartment_7660", "id": "reaction_10788637", "reactome": "R-SCE-9613494", "name": "Unwinding of DNA for the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10764032" ], "products": [ "species_10764032", "species_164121", "species_113541" ], "modifiers": [ [ "species_10763293", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W" ] }, "reaction_10764076": { "compartment": "compartment_7660", "id": "reaction_10764076", "reactome": "R-SCE-75864", "name": "Newly Formed Phosphodiester Bond Stabilized and PPi Released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764074" ], "products": [ "species_10763505", "species_113541" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10764162": { "compartment": "compartment_7660", "id": "reaction_10764162", "reactome": "R-SCE-75949", "name": "RNA Polymerase II Promoter Opening: First Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10764070" ], "products": [ "species_113582", "species_113550", "species_10764062" ], "modifiers": [ [ "species_10763293", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W" ] }, "reaction_10764829": { "compartment": "compartment_7660", "id": "reaction_10764829", "reactome": "R-SCE-111264", "name": "Addition of nucleotides between position +11 and +30", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764283" ], "products": [ "species_10764338", "species_113541" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10780889": { "compartment": "compartment_70101", "id": "reaction_10780889", "reactome": "R-SCE-5690152", "name": "USP5 cleaves polyubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10780884", "species_29356" ], "products": [ "species_10760634", "species_10780886" ], "modifiers": [ [ "species_10780884", "catalyst" ] ], "additional_components": [ "P38237", "YBR058C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38237", "YBR058C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38237", "YBR058C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10781695": { "compartment": "compartment_7660", "id": "reaction_10781695", "reactome": "R-SCE-5697009", "name": "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781688", "species_113518" ], "products": [ "species_10780391", "species_10781692" ], "modifiers": [ [ "species_10781688", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "Q01939", "YGL048C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03940", "YDR190C", "P38187", "YBL067C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P13365", "YAL040C", "P20438", "YPL256C", "Q01939", "YGL048C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03940", "YDR190C", "P38187", "YBL067C", "P13365", "YAL040C", "P20438", "YPL256C", "Q01939", "YGL048C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03940", "YDR190C", "P38187", "YBL067C" ] }, "reaction_10780495": { "compartment": "compartment_7660", "id": "reaction_10780495", "reactome": "R-SCE-5690080", "name": "USP3,SAGA deubiquitinate Histone H2A,H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10780488", "species_113518" ], "products": [ "species_10780492", "species_10760537" ], "modifiers": [ [ "species_10780488", "catalyst" ] ], "additional_components": [ "Q05027", "YMR236W", "P50102", "YMR223W", "P02294", "YBL002W", "Q12030", "YDR167W", "P28003", "YAL034C", "P32494", "YDR176W", "Q99326", "YOR338W", "Q02336", "YDR448W", "Q03330", "YGR252W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "Q05027", "YMR236W", "P50102", "YMR223W", "P02294", "YBL002W", "Q12030", "YDR167W", "P28003", "YAL034C", "P32494", "YDR176W", "Q99326", "YOR338W", "Q02336", "YDR448W", "Q03330", "YGR252W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05027", "YMR236W", "P50102", "YMR223W", "P02294", "YBL002W", "Q12030", "YDR167W", "P28003", "YAL034C", "P32494", "YDR176W", "Q99326", "YOR338W", "Q02336", "YDR448W", "Q03330", "YGR252W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W" ] }, "reaction_10771848": { "compartment": "compartment_70101", "id": "reaction_10771848", "reactome": "R-SCE-936390", "name": "CYLD mediated deubiquitination of DDX58 (RIG-I)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771819" ], "products": [ "species_10760634", "species_10771837" ], "modifiers": [ [ "species_10771845", "catalyst" ] ], "additional_components": [ "P40434", "YML133C", "P40889", "YML133C", "Q7M4S9", "YML133C", "Q03099", "YML133C", "P53819", "YNL339C", "Q99208", "YML133C", "Q07888", "YML133C", "P38721", "YML133C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40434", "YML133C", "P40889", "YML133C", "Q7M4S9", "YML133C", "Q03099", "YML133C", "P53819", "YNL339C", "Q99208", "YML133C", "Q07888", "YML133C", "P38721", "YML133C", "P33442", "RPS1A", "P23248", "RPS1B" ] }, "reaction_10779645": { "compartment": "compartment_70101", "id": "reaction_10779645", "reactome": "R-SCE-5689539", "name": "ADRM1:26S proteaseome binds USP14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779636", "species_10779641" ], "products": [ "species_10779643" ], "modifiers": [], "additional_components": [ "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W", "YFR010W", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P43593", "YFR010W", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10781707": { "compartment": "compartment_70101", "id": "reaction_10781707", "reactome": "R-SCE-6781779", "name": "USP13 deubiquitinates BECN1,USP10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781702", "species_29356" ], "products": [ "species_10781704", "species_10766135" ], "modifiers": [ [ "species_10781702", "catalyst" ] ], "additional_components": [ "P38237", "YBR058C", "Q02948", "YPL120W", "P38237", "YBR058C", "Q02948", "YPL120W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38237", "YBR058C", "Q02948", "YPL120W" ] }, "reaction_10780394": { "compartment": "compartment_7660", "id": "reaction_10780394", "reactome": "R-SCE-5689950", "name": "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10779716" ], "products": [ "species_10780391", "species_10779722" ], "modifiers": [ [ "species_10779716", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "P50101", "YMR304W", "Q08747", "YOR295W", "P53916", "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P50101", "YMR304W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P53916", "YNL128W", "Q05024", "YMR233W", "P50101", "YMR304W", "Q08747", "YOR295W", "P53916", "YNL128W" ] }, "reaction_10761428": { "compartment": "compartment_70101", "id": "reaction_10761428", "reactome": "R-SCE-70523", "name": "PXLP-K314-GPT transaminates L-Ala to form PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29432" ], "products": [ "species_29404", "species_29398" ], "modifiers": [ [ "species_10761425", "catalyst" ] ], "additional_components": [ "P52893", "YLR089C" ] }, "reaction_10771076": { "compartment": "compartment_5460", "id": "reaction_10771076", "reactome": "R-SCE-507749", "name": "PXLP-K341-GPT2 transaminates PYR to form L-Ala", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113557" ], "products": [ "species_113594", "species_379697" ], "modifiers": [ [ "species_10771073", "catalyst" ] ], "additional_components": [ "P52893", "YLR089C", "P52892", "YDR111C" ] }, "reaction_10787978": { "compartment": "compartment_5460", "id": "reaction_10787978", "reactome": "R-SCE-9012721", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012724", "species_9012592" ], "products": [ "species_1614595", "species_113557" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C" ] }, "reaction_10788188": { "compartment": "compartment_5460", "id": "reaction_10788188", "reactome": "R-SCE-9013471", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013199", "species_9012592" ], "products": [ "species_113557", "species_9013191" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C" ] }, "reaction_10788112": { "compartment": "compartment_5460", "id": "reaction_10788112", "reactome": "R-SCE-9013198", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_9013199" ], "products": [ "species_9013207", "species_9013191" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C" ] }, "reaction_10788190": { "compartment": "compartment_5460", "id": "reaction_10788190", "reactome": "R-SCE-9013533", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013543", "species_9013199" ], "products": [ "species_113557", "species_9013191" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C" ] }, "reaction_10773393": { "compartment": "compartment_70101", "id": "reaction_10773393", "reactome": "R-SCE-1614567", "name": "Excess homocysteine yields homolanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369" ], "products": [ "species_1614532", "species_1614594" ], "modifiers": [ [ "species_10773390", "catalyst" ], [ "species_174369", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10773404": { "compartment": "compartment_70101", "id": "reaction_10773404", "reactome": "R-SCE-1614631", "name": "Homocysteine is degraded to oxobutanoate and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369", "species_29356" ], "products": [ "species_1614532", "species_29382", "species_936714" ], "modifiers": [ [ "species_10773390", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10773399": { "compartment": "compartment_70101", "id": "reaction_10773399", "reactome": "R-SCE-1614591", "name": "Excess cysteine yields lanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707" ], "products": [ "species_1614532", "species_1614582" ], "modifiers": [ [ "species_10773390", "catalyst" ], [ "species_111707", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10773401": { "compartment": "compartment_70101", "id": "reaction_10773401", "reactome": "R-SCE-1614614", "name": "Cysteine is degraded to serine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_29356" ], "products": [ "species_1614532", "species_200736" ], "modifiers": [ [ "species_10773390", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10788493": { "compartment": "compartment_5460", "id": "reaction_10788493", "reactome": "R-SCE-9034756", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787975", "species_9012592" ], "products": [ "species_113557", "species_10788491" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C", "YOR251C", "YOR251C" ] }, "reaction_10773382": { "compartment": "compartment_70616", "id": "reaction_10773382", "reactome": "R-SCE-1614546", "name": "Sulfate is exported to the cytosol in exchange for dicarboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614584", "species_198498" ], "products": [ "species_174375", "species_113544" ], "modifiers": [ [ "species_10768552", "catalyst" ] ], "additional_components": [ "YLR348C" ] }, "reaction_10778010": { "compartment": "compartment_70101", "id": "reaction_10778010", "reactome": "R-SCE-5623508", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10778008" ], "products": [ "species_10778006", "species_29420" ], "modifiers": [ [ "species_10768383", "catalyst" ] ], "additional_components": [ "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "P11076", "YDL192W", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C" ] }, "reaction_10773127": { "compartment": "compartment_12045", "id": "reaction_10773127", "reactome": "R-SCE-1482825", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[11]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10773124", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10773178": { "compartment": "compartment_12045", "id": "reaction_10773178", "reactome": "R-SCE-1482932", "name": "PI is hydrolyzed to 2-acyl LPI by PLA2[13]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498737", "species_1524021" ], "modifiers": [ [ "species_10773175", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10773030": { "compartment": "compartment_12045", "id": "reaction_10773030", "reactome": "R-SCE-1482626", "name": "2-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498737", "species_1500578" ], "products": [ "species_76194", "species_426639" ], "modifiers": [ [ "species_10772972", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10772975": { "compartment": "compartment_12045", "id": "reaction_10772975", "reactome": "R-SCE-1482598", "name": "1-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498733", "species_1500578" ], "products": [ "species_76194", "species_426639" ], "modifiers": [ [ "species_10772972", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10773155": { "compartment": "compartment_12045", "id": "reaction_10773155", "reactome": "R-SCE-1482868", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[12]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10764802": { "compartment": "compartment_7660", "id": "reaction_10764802", "reactome": "R-SCE-110316", "name": "POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764798", "species_10764794" ], "products": [ "species_10764800" ], "modifiers": [], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "YDR419W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10764811": { "compartment": "compartment_7660", "id": "reaction_10764811", "reactome": "R-SCE-110317", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764800", "species_29604" ], "products": [ "species_113541", "species_10764808" ], "modifiers": [ [ "species_10764800", "catalyst" ] ], "additional_components": [ "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10778443": { "compartment": "compartment_7660", "id": "reaction_10778443", "reactome": "R-SCE-5654985", "name": "SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778439", "species_10778423" ], "products": [ "species_10778441" ], "modifiers": [], "additional_components": [ "P33755", "YBR170C", "P53044", "YGR048W", "P25694", "YDL126C", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P33755", "YBR170C", "P38630", "YOR217W", "P40339", "YOL094C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P53044", "YGR048W", "P25694", "YDL126C" ] }, "reaction_10778448": { "compartment": "compartment_7660", "id": "reaction_10778448", "reactome": "R-SCE-5654989", "name": "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10778441" ], "products": [ "species_113582", "species_10778445", "species_10764794" ], "modifiers": [ [ "species_10778441", "catalyst" ] ], "additional_components": [ "Q04049", "YDR419W", "P33755", "YBR170C", "P38630", "YOR217W", "P40339", "YOL094C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P53044", "YGR048W", "P25694", "YDL126C", "P33755", "YBR170C", "P38630", "YOR217W", "P40339", "YOL094C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P53044", "YGR048W", "P25694", "YDL126C", "YDR419W", "Q04049", "YDR419W", "P33755", "YBR170C", "P38630", "YOR217W", "P40339", "YOL094C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P53044", "YGR048W", "P25694", "YDL126C" ] }, "reaction_10764818": { "compartment": "compartment_7660", "id": "reaction_10764818", "reactome": "R-SCE-110319", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10764808" ], "products": [ "species_113541", "species_10764815" ], "modifiers": [ [ "species_10764808", "catalyst" ] ], "additional_components": [ "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10785235": { "compartment": "compartment_12045", "id": "reaction_10785235", "reactome": "R-SCE-6814254", "name": "PNPLA6 hydrolyzes LysoPtdCho", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6814253", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10785232", "catalyst" ] ], "additional_components": [ "YML059C" ] }, "reaction_10785323": { "compartment": "compartment_876", "id": "reaction_10785323", "reactome": "R-SCE-6814797", "name": "ENPP6 hydrolyzes lysophosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2239407" ], "products": [ "species_6814794", "species_6814795" ], "modifiers": [ [ "species_10785320", "catalyst" ] ], "additional_components": [ "P39997", "YEL016C", "P25353", "YCR026C" ] }, "reaction_10773783": { "compartment": "compartment_70101", "id": "reaction_10773783", "reactome": "R-SCE-1855179", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629770" ], "modifiers": [ [ "species_10773780", "catalyst" ] ], "additional_components": [ "YDR315C" ] }, "reaction_10773735": { "compartment": "compartment_70101", "id": "reaction_10773735", "reactome": "R-SCE-1855165", "name": "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_1629765", "species_29372" ], "modifiers": [ [ "species_10773732", "catalyst" ] ], "additional_components": [ "CHEBI:62924", "species_2023931", "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773751": { "compartment": "compartment_7660", "id": "reaction_10773751", "reactome": "R-SCE-1855176", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023929" ], "modifiers": [ [ "species_10773748", "catalyst" ] ], "additional_components": [ "YDR315C" ] }, "reaction_10773839": { "compartment": "compartment_70101", "id": "reaction_10773839", "reactome": "R-SCE-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_994123", "species_29372" ], "modifiers": [ [ "species_10773740", "catalyst" ] ], "additional_components": [ "P50942", "YNL106C", "Q08227", "YOL065C" ] }, "reaction_10773738": { "compartment": "compartment_70101", "id": "reaction_10773738", "reactome": "R-SCE-1855166", "name": "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023943", "species_29356" ], "products": [ "species_29372", "species_994141" ], "modifiers": [ [ "species_10773726", "catalyst" ] ], "additional_components": [ "species_1629736", "species_2023922", "CHEBI:62927", "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773870": { "compartment": "compartment_70101", "id": "reaction_10773870", "reactome": "R-SCE-1855223", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629755" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773743": { "compartment": "compartment_70101", "id": "reaction_10773743", "reactome": "R-SCE-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114520", "species_29356" ], "products": [ "species_1629739", "species_29372" ], "modifiers": [ [ "species_10773740", "catalyst" ] ], "additional_components": [ "P50942", "YNL106C", "Q08227", "YOL065C" ] }, "reaction_10773702": { "compartment": "compartment_7660", "id": "reaction_10773702", "reactome": "R-SCE-1855157", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023932" ], "products": [ "species_113582", "species_2023931" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773778": { "compartment": "compartment_70101", "id": "reaction_10773778", "reactome": "R-SCE-1855178", "name": "Glc6P is isomerised to I3P by ISYNA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629756" ], "products": [ "species_1629731" ], "modifiers": [ [ "species_10773775", "catalyst" ] ], "additional_components": [ "species_113526", "P11986", "YJL153C" ] }, "reaction_10773810": { "compartment": "compartment_70101", "id": "reaction_10773810", "reactome": "R-SCE-1855205", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_114520", "species_29372" ], "modifiers": [ [ "species_10773807", "catalyst" ] ], "additional_components": [ "P53916", "YNL128W", "species_109496" ] }, "reaction_10773826": { "compartment": "compartment_876", "id": "reaction_10773826", "reactome": "R-SCE-1855213", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_994123", "species_29372" ], "modifiers": [ [ "species_10773821", "catalyst" ] ], "additional_components": [ "YOL065C" ] }, "reaction_10773715": { "compartment": "compartment_70101", "id": "reaction_10773715", "reactome": "R-SCE-1855158", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629759" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773968": { "compartment": "compartment_70101", "id": "reaction_10773968", "reactome": "R-SCE-2023971", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023974", "species_29356" ], "products": [ "species_1629770", "species_29372" ], "modifiers": [ [ "species_10773732", "catalyst" ] ], "additional_components": [ "CHEBI:62922", "species_2023932", "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773816": { "compartment": "compartment_70101", "id": "reaction_10773816", "reactome": "R-SCE-1855210", "name": "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629731" ], "products": [ "species_426910", "species_29372" ], "modifiers": [ [ "species_10773680", "catalyst" ] ], "additional_components": [ "P38710", "YHR046C", "Q05533", "YDR287W", "species_109496" ] }, "reaction_10773864": { "compartment": "compartment_876", "id": "reaction_10773864", "reactome": "R-SCE-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10773861", "catalyst" ] ], "additional_components": [ "species_74016", "P32383", "YPL268W" ] }, "reaction_10773813": { "compartment": "compartment_7660", "id": "reaction_10773813", "reactome": "R-SCE-1855207", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023929" ], "products": [ "species_113582", "species_2023940" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773867": { "compartment": "compartment_876", "id": "reaction_10773867", "reactome": "R-SCE-1855222", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114520", "species_29356" ], "products": [ "species_1629739", "species_29372" ], "modifiers": [ [ "species_10773821", "catalyst" ] ], "additional_components": [ "YOL065C" ] }, "reaction_10773786": { "compartment": "compartment_7660", "id": "reaction_10773786", "reactome": "R-SCE-1855181", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023922" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773876": { "compartment": "compartment_70101", "id": "reaction_10773876", "reactome": "R-SCE-1855227", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629770", "species_113592" ], "products": [ "species_29370", "species_1629765" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773768": { "compartment": "compartment_70101", "id": "reaction_10773768", "reactome": "R-SCE-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10773765", "catalyst" ] ], "additional_components": [ "P32383", "YPL268W", "species_74016" ] }, "reaction_10773799": { "compartment": "compartment_70101", "id": "reaction_10773799", "reactome": "R-SCE-1855193", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629736" ], "products": [ "species_29370", "species_1629738" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773836": { "compartment": "compartment_70101", "id": "reaction_10773836", "reactome": "R-SCE-1855216", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629770", "species_113592" ], "products": [ "species_29370", "species_1629740" ], "modifiers": [ [ "species_10773791", "catalyst" ] ], "additional_components": [ "YLR410W" ] }, "reaction_10773873": { "compartment": "compartment_7660", "id": "reaction_10773873", "reactome": "R-SCE-1855224", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023940", "species_29358" ], "products": [ "species_113582", "species_2023941" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773805": { "compartment": "compartment_70101", "id": "reaction_10773805", "reactome": "R-SCE-1855198", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_29356" ], "products": [ "species_1629770", "species_29372" ], "modifiers": [ [ "species_10773732", "catalyst" ] ], "additional_components": [ "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773819": { "compartment": "compartment_70101", "id": "reaction_10773819", "reactome": "R-SCE-1855211", "name": "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629753", "species_29356" ], "products": [ "species_426910", "species_29372" ], "modifiers": [ [ "species_10773680", "catalyst" ] ], "additional_components": [ "P38710", "YHR046C", "Q05533", "YDR287W", "species_109496" ] }, "reaction_10773796": { "compartment": "compartment_70101", "id": "reaction_10773796", "reactome": "R-SCE-1855182", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629732" ], "modifiers": [ [ "species_10773791", "catalyst" ] ], "additional_components": [ "YLR410W" ] }, "reaction_10773970": { "compartment": "compartment_70101", "id": "reaction_10773970", "reactome": "R-SCE-2023973", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_2023974", "species_29372" ], "modifiers": [ [ "species_10773732", "catalyst" ] ], "additional_components": [ "CHEBI:62924", "species_2023931", "CHEBI:62922", "species_2023932", "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773879": { "compartment": "compartment_7660", "id": "reaction_10773879", "reactome": "R-SCE-1855230", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023922", "species_29358" ], "products": [ "species_113582", "species_2023948" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773802": { "compartment": "compartment_70101", "id": "reaction_10773802", "reactome": "R-SCE-1855194", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629740" ], "products": [ "species_29370", "species_1629732" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773833": { "compartment": "compartment_12045", "id": "reaction_10773833", "reactome": "R-SCE-1855214", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023856", "species_29356" ], "products": [ "species_114520", "species_1500596" ], "modifiers": [ [ "species_10773830", "catalyst" ] ], "additional_components": [ "species_74016", "P32383", "YPL268W" ] }, "reaction_10773683": { "compartment": "compartment_70101", "id": "reaction_10773683", "reactome": "R-SCE-1855154", "name": "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_870330", "species_29356" ], "products": [ "species_426910", "species_29372" ], "modifiers": [ [ "species_10773680", "catalyst" ] ], "additional_components": [ "P38710", "YHR046C", "Q05533", "YDR287W", "species_109496" ] }, "reaction_10778372": { "compartment": "compartment_7660", "id": "reaction_10778372", "reactome": "R-SCE-5653780", "name": "USP43 binds ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778364", "species_10778368" ], "products": [ "species_10778370" ], "modifiers": [], "additional_components": [ "P39538", "YJL197W", "P32571", "YDR069C", "P39944", "YER144C", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P39538", "YJL197W", "P38251", "YBR087W", "P32571", "YDR069C", "P15873", "YBR088C", "P38629", "YNL290W", "P39944", "YER144C" ] }, "reaction_10778378": { "compartment": "compartment_7660", "id": "reaction_10778378", "reactome": "R-SCE-5653838", "name": "POLD,POLE binds deISGylated PCNA after TLS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778374", "species_10764822" ], "products": [ "species_10778376" ], "modifiers": [], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P40366", "YJL065C", "P27344", "YBR278W", "P26754", "YNL312W", "P40339", "YOL094C", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10765202": { "compartment": "compartment_7660", "id": "reaction_10765202", "reactome": "R-SCE-113504", "name": "Detection of damage during initiation of DNA synthesis in S-phase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760830" ], "products": [ "species_10760246", "species_113656" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W" ] }, "reaction_10767970": { "compartment": "compartment_12045", "id": "reaction_10767970", "reactome": "R-SCE-203979", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767870", "species_10767966" ], "products": [ "species_10767968" ], "modifiers": [], "additional_components": [ "P20606", "YPL218W", "species_29438", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "species_29438" ] }, "reaction_10772440": { "compartment": "compartment_17957", "id": "reaction_10772440", "reactome": "R-SCE-983158", "name": "Trimming of peptides in ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983034" ], "products": [ "species_983033", "species_8943716" ], "modifiers": [ [ "species_10772437", "catalyst" ] ], "additional_components": [ "P40462", "YIL137C", "P32454", "YKL157W", "P37898", "YHR047C" ] }, "reaction_10761054": { "compartment": "compartment_7660", "id": "reaction_10761054", "reactome": "R-SCE-69199", "name": "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10761046" ], "products": [ "species_113550", "species_10761041" ], "modifiers": [ [ "species_10761051", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "YMR036C" ] }, "reaction_10766479": { "compartment": "compartment_7660", "id": "reaction_10766479", "reactome": "R-SCE-188350", "name": "CAK-mediated phosphorylation of Cyclin E:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10761041" ], "products": [ "species_113582", "species_10760879" ], "modifiers": [ [ "species_10763257", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03290", "YDR460W", "P37366", "YPR025C", "P06242", "YDL108W" ] }, "reaction_10760390": { "compartment": "compartment_7660", "id": "reaction_10760390", "reactome": "R-SCE-68918", "name": "CDK and DDK associate with the Mcm10:pre-replicative complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760326", "species_10760314", "species_10760375" ], "products": [ "species_10760377" ], "modifiers": [], "additional_components": [ "P06243", "YDL017W", "P32325", "YDR052C", "P00546", "YBR160W", "P24279", "MCM3", "P29469", "MCM2", "P32833", "ORC2", "P38132", "MCM7", "P54791", "ORC4", "P54784", "phospho-ORC1", "P30665", "MCM4", "P32354", "YIL150C", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P54790", "ORC3", "P29496", "MCM5", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "P54791", "ORC4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10760383": { "compartment": "compartment_7660", "id": "reaction_10760383", "reactome": "R-SCE-68914", "name": "DNA polymerase alpha:primase binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760246", "species_10760277" ], "products": [ "species_10760279" ], "modifiers": [ [ "species_10760381", "catalyst" ] ], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P20457", "YKL045W", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P22336", "YAR007C", "P54791", "ORC4", "P26754", "YNL312W", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10761037": { "compartment": "compartment_70101", "id": "reaction_10761037", "reactome": "R-SCE-69191", "name": "Formation of Cyclin E:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760999", "species_10761033" ], "products": [ "species_10761035" ], "modifiers": [], "additional_components": [ "YBR160W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760840": { "compartment": "compartment_7660", "id": "reaction_10760840", "reactome": "R-SCE-68960", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760275", "species_68419" ], "products": [ "species_10760277" ], "modifiers": [ [ "species_10760381", "catalyst" ] ], "additional_components": [ "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P22336", "YAR007C", "P54791", "ORC4", "P26754", "YNL312W", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10760838": { "compartment": "compartment_7660", "id": "reaction_10760838", "reactome": "R-SCE-68954", "name": "Mcm2-7 is phosphorylated by DDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10760363" ], "products": [ "species_113582", "species_10760835" ], "modifiers": [ [ "species_10760326", "catalyst" ] ], "additional_components": [ "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "species_29372", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29496", "MCM5", "P06243", "YDL017W", "P32325", "YDR052C" ] }, "reaction_10765436": { "compartment": "compartment_13231", "id": "reaction_10765436", "reactome": "R-SCE-157906", "name": "Translocation of Cyclin E:Cdk2 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761035" ], "products": [ "species_10761041" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760400": { "compartment": "compartment_7660", "id": "reaction_10760400", "reactome": "R-SCE-68919", "name": "Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760396", "species_10760331" ], "products": [ "species_10760398" ], "modifiers": [], "additional_components": [ "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P32833", "ORC2", "P54791", "ORC4", "P30665", "MCM4", "P54784", "phospho-ORC1", "P09119", "CDC6", "P53091", "MCM6", "P50874", "ORC5", "P29496", "MCM5", "P54790", "ORC3", "YIL150C", "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P32833", "ORC2", "P54791", "ORC4", "P30665", "MCM4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P09119", "CDC6", "P53091", "MCM6", "P50874", "ORC5", "P29496", "MCM5", "P54790", "ORC3" ] }, "reaction_10760388": { "compartment": "compartment_7660", "id": "reaction_10760388", "reactome": "R-SCE-68917", "name": "Cdc45 associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760377", "species_10760305" ], "products": [ "species_10760379" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "P54791", "ORC4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3", "YLR103C", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P54791", "ORC4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10760386": { "compartment": "compartment_7660", "id": "reaction_10760386", "reactome": "R-SCE-68916", "name": "DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760379", "species_10760300" ], "products": [ "species_10760381" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P54791", "ORC4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3", "P22336", "YAR007C", "P26754", "YNL312W", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P22336", "YAR007C", "P54791", "ORC4", "P26754", "YNL312W", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10766866": { "compartment": "compartment_13231", "id": "reaction_10766866", "reactome": "R-SCE-193666", "name": "Active JNK moves to the nucleus and phosphorylates different transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765974" ], "products": [ "species_10765931" ], "modifiers": [], "additional_components": [ "YPR054W", "YPR054W" ] }, "reaction_10775479": { "compartment": "compartment_7660", "id": "reaction_10775479", "reactome": "R-SCE-3318486", "name": "KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_113560" ], "products": [ "species_2485002", "species_10775464" ], "modifiers": [ [ "species_10775476", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q12311", "YPR031W", "Q08465", "YOR064C", "Q08649", "YOR244W", "P50947", "YNL097C", "P38806", "YHR090C", "P47128", "YJR082C" ] }, "reaction_10775918": { "compartment": "compartment_7660", "id": "reaction_10775918", "reactome": "R-SCE-3662318", "name": "Type B histone acetlytransferase complex acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763701", "species_113560" ], "products": [ "species_2485002", "species_10775881" ], "modifiers": [ [ "species_10775915", "catalyst" ] ], "additional_components": [ "YBR009C", "YBR009C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P39984", "YEL056W", "Q12363", "YOR230W", "P13712", "YBR195C", "Q12341", "YPL001W" ] }, "reaction_10775460": { "compartment": "compartment_7660", "id": "reaction_10775460", "reactome": "R-SCE-3318415", "name": "ATF2 acetylates histone H2B, H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775434", "species_113560" ], "products": [ "species_2485002", "species_10775457" ], "modifiers": [ [ "species_10765915", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P02293", "YDR224C", "P02294", "YBL002W", "P02309", "YBR009C", "P02293", "YDR224C", "P39970", "YER045C", "P40535", "YIL036W", "Q02100", "YNL167C" ] }, "reaction_10775428": { "compartment": "compartment_7660", "id": "reaction_10775428", "reactome": "R-SCE-3318413", "name": "KAT7-containing ING4/5 complexes acetylate Me3K-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774208", "species_113560" ], "products": [ "species_2485002", "species_10775382" ], "modifiers": [ [ "species_10775425", "catalyst" ] ], "additional_components": [ "YKL049C", "YKL049C", "Q08465", "YOR064C", "Q08649", "YOR244W", "P50947", "YNL097C", "P38806", "YHR090C", "P47128", "YJR082C" ] }, "reaction_10764336": { "compartment": "compartment_7660", "id": "reaction_10764336", "reactome": "R-SCE-77069", "name": "RNA Polymerase II CTD (phosphorylated) binds to CE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764328", "species_10764334" ], "products": [ "species_10764330" ], "modifiers": [], "additional_components": [ "YGL130W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q01159", "YGL130W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10764381": { "compartment": "compartment_7660", "id": "reaction_10764381", "reactome": "R-SCE-77085", "name": "Dissociation of transcript with 5'-GMP from GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764374" ], "products": [ "species_10764379" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764377": { "compartment": "compartment_7660", "id": "reaction_10764377", "reactome": "R-SCE-77083", "name": "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764369" ], "products": [ "species_10764374" ], "modifiers": [ [ "species_10764369", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "species_113578", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "species_113578", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764360": { "compartment": "compartment_7660", "id": "reaction_10764360", "reactome": "R-SCE-77077", "name": "Capping complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_72084", "species_10764354", "species_29428" ], "products": [ "species_10764358" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764365": { "compartment": "compartment_7660", "id": "reaction_10764365", "reactome": "R-SCE-77078", "name": "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764358" ], "products": [ "species_113550", "species_10764362" ], "modifiers": [ [ "species_10764358", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764332": { "compartment": "compartment_7660", "id": "reaction_10764332", "reactome": "R-SCE-77068", "name": "Activation of GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764330" ], "products": [ "species_10764330" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q01159", "YGL130W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q01159", "YGL130W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10764386": { "compartment": "compartment_7660", "id": "reaction_10764386", "reactome": "R-SCE-77090", "name": "Methylation of GMP-cap by RNA Methyltransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764379", "species_77087" ], "products": [ "species_10762304", "species_10764383", "species_10764352", "species_10763293", "species_77502" ], "modifiers": [ [ "species_10764379", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P32783", "YBR236C", "Q01159", "YGL130W", "YML010W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764388": { "compartment": "compartment_7660", "id": "reaction_10764388", "reactome": "R-SCE-77094", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762228", "species_10762223" ], "products": [ "species_10762230" ], "modifiers": [], "additional_components": [ "YMR125W", "YPL178W", "P34160", "YMR125W", "Q08920", "YPL178W" ] }, "reaction_10764356": { "compartment": "compartment_7660", "id": "reaction_10764356", "reactome": "R-SCE-77073", "name": "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764330", "species_10764352", "species_10764346" ], "products": [ "species_10764354" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q01159", "YGL130W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "YML010W", "YBR236C", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764372": { "compartment": "compartment_7660", "id": "reaction_10764372", "reactome": "R-SCE-77081", "name": "Formation of the CE:GMP intermediate complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113571", "species_10764362" ], "products": [ "species_111349", "species_10764369" ], "modifiers": [ [ "species_10764362", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "species_113578", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764390": { "compartment": "compartment_7660", "id": "reaction_10764390", "reactome": "R-SCE-77095", "name": "Recognition and binding of the mRNA cap by the cap-binding complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762304", "species_10762230" ], "products": [ "species_10762306" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P34160", "YMR125W", "Q08920", "YPL178W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764820": { "compartment": "compartment_7660", "id": "reaction_10764820", "reactome": "R-SCE-110322", "name": "Formation of Pol zeta complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764773", "species_10764778" ], "products": [ "species_10764780" ], "modifiers": [], "additional_components": [ "YPL167C", "YIL139C", "P38927", "YIL139C", "P14284", "YPL167C" ] }, "reaction_10764789": { "compartment": "compartment_7660", "id": "reaction_10764789", "reactome": "R-SCE-110311", "name": "POLZ extends translesion synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764782", "species_30555" ], "products": [ "species_10764780", "species_10764786", "species_113541" ], "modifiers": [ [ "species_10764782", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38927", "YIL139C", "P14284", "YPL167C", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C" ] }, "reaction_10778576": { "compartment": "compartment_7660", "id": "reaction_10778576", "reactome": "R-SCE-5656158", "name": "POLZ elongates POLI-incorporated dNMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778564", "species_30555" ], "products": [ "species_10764780", "species_113541", "species_10778573", "species_10764742" ], "modifiers": [ [ "species_10778564", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38927", "YIL139C", "P14284", "YPL167C", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_109496", "P38629", "YNL290W", "YOR346W", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C" ] }, "reaction_10778296": { "compartment": "compartment_7660", "id": "reaction_10778296", "reactome": "R-SCE-5652151", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764780", "species_10764765" ], "products": [ "species_10764782" ], "modifiers": [], "additional_components": [ "P38927", "YIL139C", "P14284", "YPL167C", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C" ] }, "reaction_10764759": { "compartment": "compartment_7660", "id": "reaction_10764759", "reactome": "R-SCE-110307", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764755", "species_10764742" ], "products": [ "species_10764757" ], "modifiers": [], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "YOR346W", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10778567": { "compartment": "compartment_7660", "id": "reaction_10778567", "reactome": "R-SCE-5656148", "name": "POLI incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10778558" ], "products": [ "species_10778564", "species_113541" ], "modifiers": [ [ "species_10778558", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C" ] }, "reaction_10778548": { "compartment": "compartment_7660", "id": "reaction_10778548", "reactome": "R-SCE-5655965", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10778536" ], "products": [ "species_10764780", "species_10778545", "species_113541", "species_10764742" ], "modifiers": [ [ "species_10778536", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527", "P38927", "YIL139C", "P14284", "YPL167C", "P38630", "YOR217W", "P40339", "YOL094C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527", "YOR346W", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527" ] }, "reaction_10764768": { "compartment": "compartment_7660", "id": "reaction_10764768", "reactome": "R-SCE-110308", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10764757" ], "products": [ "species_10764765" ], "modifiers": [ [ "species_10764757", "catalyst" ] ], "additional_components": [ "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10778539": { "compartment": "compartment_7660", "id": "reaction_10778539", "reactome": "R-SCE-5655892", "name": "POLK incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10778530" ], "products": [ "species_10778536", "species_113541" ], "modifiers": [ [ "species_10778530", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38927", "YIL139C", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38927", "YIL139C", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527" ] }, "reaction_10773254": { "compartment": "compartment_70101", "id": "reaction_10773254", "reactome": "R-SCE-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_264618" ], "products": [ "species_29370", "species_1524071" ], "modifiers": [ [ "species_10773251", "catalyst" ] ], "additional_components": [ "P20485", "YLR133W", "Q03764", "YDR147W" ] }, "reaction_10773327": { "compartment": "compartment_12045", "id": "reaction_10773327", "reactome": "R-SCE-1483203", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_29372", "species_1500596" ], "modifiers": [ [ "species_10773324", "catalyst" ] ], "additional_components": [ "P32567", "YMR165C", "species_109496" ] }, "reaction_10773195": { "compartment": "compartment_12045", "id": "reaction_10773195", "reactome": "R-SCE-1482961", "name": "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524060", "species_1500596" ], "products": [ "species_109395", "species_426925" ], "modifiers": [ [ "species_10773192", "catalyst" ] ], "additional_components": [ "P17898", "YNL130C", "P22140", "YHR123W", "species_113527", "species_109496" ] }, "reaction_10773296": { "compartment": "compartment_12045", "id": "reaction_10773296", "reactome": "R-SCE-1483174", "name": "PE is methylated to PC by PEMT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_71284" ], "products": [ "species_426925", "species_71285" ], "modifiers": [ [ "species_10773293", "catalyst" ] ], "additional_components": [ "YJR073C" ] }, "reaction_10768148": { "compartment": "compartment_70101", "id": "reaction_10768148", "reactome": "R-SCE-264622", "name": "Cho is acetylated to AcCho by CHAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618", "species_76183" ], "products": [ "species_76194", "species_264643" ], "modifiers": [ [ "species_10768145", "catalyst" ] ], "additional_components": [ "YML042W" ] }, "reaction_10773219": { "compartment": "compartment_20699", "id": "reaction_10773219", "reactome": "R-SCE-1482973", "name": "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524057", "species_1524060" ], "products": [ "species_109395", "species_429785" ], "modifiers": [ [ "species_10773216", "catalyst" ] ], "additional_components": [ "P17898", "YNL130C", "P22140", "YHR123W", "species_113527", "species_109496" ] }, "reaction_10781570": { "compartment": "compartment_876", "id": "reaction_10781570", "reactome": "R-SCE-5694485", "name": "ABHD3 hydrolyses LPC(14:0) to 1AGPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694502", "species_29356" ], "products": [ "species_1861754", "species_5694457" ], "modifiers": [ [ "species_10781567", "catalyst" ] ], "additional_components": [ "Q03649", "YMR210W", "Q02891", "YPL095C", "P38295", "YBR177C" ] }, "reaction_10773273": { "compartment": "compartment_12045", "id": "reaction_10773273", "reactome": "R-SCE-1483081", "name": "PCho and CTP are condensed to CDP-Cho by PCYT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_1524071" ], "products": [ "species_111294", "species_1524060" ], "modifiers": [ [ "species_10773270", "catalyst" ] ], "additional_components": [ "P13259", "YGR202C" ] }, "reaction_10761101": { "compartment": "compartment_7660", "id": "reaction_10761101", "reactome": "R-SCE-69608", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761051", "species_29358" ], "products": [ "species_113582", "species_10761063" ], "modifiers": [ [ "species_10761098", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "YDL101C" ] }, "reaction_10761061": { "compartment": "compartment_70101", "id": "reaction_10761061", "reactome": "R-SCE-69600", "name": "Proteolytic degradation of ubiquitinated-Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761059" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P23748", "YMR036C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10761089": { "compartment": "compartment_7660", "id": "reaction_10761089", "reactome": "R-SCE-69604", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761051", "species_29358" ], "products": [ "species_113582", "species_10761063" ], "modifiers": [ [ "species_10761086", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "P36002", "YKL198C", "P47116", "YJR059W", "P06782", "YDR477W" ] }, "reaction_10765884": { "compartment": "compartment_947587", "id": "reaction_10765884", "reactome": "R-SCE-167415", "name": "G-protein alpha subunit is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764870", "species_29420" ], "products": [ "species_29438", "species_10764965" ], "modifiers": [ [ "species_10764864", "catalyst" ] ], "additional_components": [ "species_29438", "P10823", "YER020W", "species_29420", "P10823", "YER020W", "YER020W" ] }, "reaction_10777703": { "compartment": "compartment_12045", "id": "reaction_10777703", "reactome": "R-SCE-5362412", "name": "SYVN1 ubiquitinates Hh C-terminal fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777696", "species_10760634" ], "products": [ "species_10777700" ], "modifiers": [ [ "species_10777696", "catalyst" ] ], "additional_components": [ "P38307", "YBR201W", "Q05787", "YLR207W", "Q99220", "YDR057W", "Q08109", "YOL013C", "P25694", "YDL126C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38307", "YBR201W", "Q05787", "YLR207W", "Q99220", "YDR057W", "Q08109", "YOL013C", "P25694", "YDL126C", "P38307", "YBR201W", "Q05787", "YLR207W", "Q99220", "YDR057W", "Q08109", "YOL013C", "P25694", "YDL126C" ] }, "reaction_10777910": { "compartment": "compartment_5263232", "id": "reaction_10777910", "reactome": "R-SCE-5610749", "name": "cAMP dissociates PKA, promoting GLI processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10777906" ], "products": [ "species_10777900", "species_10777908" ], "modifiers": [], "additional_components": [ "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "P05986", "YKL166C", "P06245", "YPL203W", "P06244", "YJL164C", "P07278", "YIL033C", "species_30389" ] }, "reaction_10768868": { "compartment": "compartment_17947", "id": "reaction_10768868", "reactome": "R-SCE-382613", "name": "PEX-19 docks ABCD1/D2/D3 to peroximal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768844", "species_10768866" ], "products": [ "species_10768844", "species_10768836", "species_10768864" ], "modifiers": [], "additional_components": [ "YDR329C", "Q07418", "YDL065C", "P34230", "YKL188C", "P41909", "YPL147W", "YDR329C", "P34230", "YKL188C", "P41909", "YPL147W", "YDL065C" ] }, "reaction_10772903": { "compartment": "compartment_70101", "id": "reaction_10772903", "reactome": "R-SCE-1454916", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_1454930" ], "products": [ "species_29370", "species_1454919", "species_29372" ], "modifiers": [ [ "species_10772900", "catalyst" ] ], "additional_components": [ "P14772", "YLL015W", "P39109", "YDR135C", "P32386", "YLL048C", "P38735", "YHL035C", "P53049", "YGR281W", "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10768883": { "compartment": "compartment_876", "id": "reaction_10768883", "reactome": "R-SCE-383190", "name": "HCO3- transport through ion channel", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_29356" ], "products": [ "species_29370", "species_425425", "species_29372" ], "modifiers": [ [ "species_10768880", "catalyst" ] ], "additional_components": [ "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10786350": { "compartment": "compartment_876", "id": "reaction_10786350", "reactome": "R-SCE-8866851", "name": "CFTR transits to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786344" ], "products": [ "species_10768880" ], "modifiers": [], "additional_components": [ "P0CE68", "YKR103W", "P12866", "YKL209C", "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10768816": { "compartment": "compartment_70616", "id": "reaction_10768816", "reactome": "R-SCE-382560", "name": "ABC7, mABC1 and mABC2 mediate heme transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_189444", "species_113593" ], "products": [ "species_113548", "species_113581", "species_71185" ], "modifiers": [ [ "species_10768813", "catalyst" ] ], "additional_components": [ "P40416", "ATM1" ] }, "reaction_10786348": { "compartment": "compartment_70101", "id": "reaction_10786348", "reactome": "R-SCE-8866553", "name": "misfolded CFTR is degraded by the 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786346" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P0CE68", "YKR103W", "P12866", "YKL209C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10779080": { "compartment": "compartment_70101", "id": "reaction_10779080", "reactome": "R-SCE-5678863", "name": "CFTR transports Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_352022", "species_29356" ], "products": [ "species_29370", "species_188972", "species_29372" ], "modifiers": [ [ "species_10768880", "catalyst" ] ], "additional_components": [ "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10768839": { "compartment": "compartment_17947", "id": "reaction_10768839", "reactome": "R-SCE-382575", "name": "ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_382577", "species_113592", "species_29356" ], "products": [ "species_29370", "species_382571", "species_29372" ], "modifiers": [ [ "species_10768836", "catalyst" ] ], "additional_components": [ "P34230", "YKL188C", "P41909", "YPL147W" ] }, "reaction_10789057": { "compartment": "compartment_984", "id": "reaction_10789057", "reactome": "R-SCE-9673053", "name": "PM20D1 transforms oleoyl-phe from oleate and phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351993", "species_9673048" ], "products": [ "species_9673044", "species_109276" ], "modifiers": [ [ "species_10789054", "catalyst" ] ], "additional_components": [ "YJL172W" ] }, "reaction_10789059": { "compartment": "compartment_984", "id": "reaction_10789059", "reactome": "R-SCE-9673054", "name": "PM20D1 hydrolyzes oleoyl-phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9673044", "species_109276" ], "products": [ "species_351993", "species_9673048" ], "modifiers": [ [ "species_10789054", "catalyst" ] ], "additional_components": [ "YJL172W" ] }, "reaction_10784879": { "compartment": "compartment_20699", "id": "reaction_10784879", "reactome": "R-SCE-6811415", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784367", "species_10784862" ], "products": [ "species_10784864" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P01123", "YFL038C", "species_29438", "P47102", "YJR031C", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "species_29438" ] }, "reaction_10784874": { "compartment": "compartment_20699", "id": "reaction_10784874", "reactome": "R-SCE-6811412", "name": "Active ARF recruits coatomer to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784870", "species_10784438" ], "products": [ "species_10784872" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P43621", "YFR051C", "P53600", "YPL010W", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P41810", "YDR238C", "P47102", "YJR031C", "P11076", "YDL192W", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P41810", "YDR238C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W" ] }, "reaction_10784939": { "compartment": "compartment_20699", "id": "reaction_10784939", "reactome": "R-SCE-6811417", "name": "ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784935", "species_10784925", "species_10784872", "species_10784923", "species_10784463" ], "products": [ "species_10784937" ], "modifiers": [], "additional_components": [ "P18414", "YBL040C", "P38819", "YHR110W", "P32803", "YGL200C", "P53198", "YGL002W", "P53337", "YGR284C", "P54837", "YML012W", "Q05359", "YAR002C-A", "YLR268W", "P47102", "YJR031C", "P11076", "YDL192W", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P41810", "YDR238C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P38819", "YHR110W", "P32803", "YGL200C", "P53198", "YGL002W", "P39704", "YAL007C", "Q12403", "YDL018C", "P54837", "YML012W", "Q12450", "YOR016C", "Q05359", "YAR002C-A", "P32572", "YNL204C", "P38682", "YER122C", "P35197", "YDL226C", "P32803", "YGL200C", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P53337", "YGR284C", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P22214", "YLR268W", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C" ] }, "reaction_10784952": { "compartment": "compartment_20699", "id": "reaction_10784952", "reactome": "R-SCE-6811418", "name": "ARFGAPs stimulate ARF GTPase activity at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784937" ], "products": [ "species_10784949", "species_10784367", "species_10784463", "species_10784385" ], "modifiers": [ [ "species_10784937", "catalyst" ] ], "additional_components": [ "P32803", "YGL200C", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P53337", "YGR284C", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P22214", "YLR268W", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C", "P32803", "YGL200C", "P53198", "YGL002W", "P39704", "YAL007C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P22214", "YLR268W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P43621", "YFR051C", "P53337", "YGR284C", "P53600", "YPL010W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "Q12403", "YDL018C", "P32074", "YNL287W", "P41811", "YGL137W", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P32572", "YNL204C", "P38682", "YER122C", "P35197", "YDL226C", "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "P32803", "YGL200C", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P53337", "YGR284C", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P22214", "YLR268W", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C" ] }, "reaction_10784982": { "compartment": "compartment_12045", "id": "reaction_10784982", "reactome": "R-SCE-6811425", "name": "NSF and SNAPs bind cis-SNARE at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10784980" ], "products": [ "species_10784971" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P22214", "YLR268W", "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W" ] }, "reaction_10784974": { "compartment": "compartment_12045", "id": "reaction_10784974", "reactome": "R-SCE-6811422", "name": "NSF ATPase activity dissociates cis-SNARE at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10784971" ], "products": [ "species_10769994", "species_10781444", "species_10784957", "species_10784962", "species_10767816", "species_29372", "species_10784967" ], "modifiers": [ [ "species_10784971", "catalyst" ] ], "additional_components": [ "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W", "YBL050W", "P18759", "YBR080C", "YDR498C", "YOR075W", "YLR268W", "YGL098W", "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W" ] }, "reaction_10784868": { "compartment": "compartment_20699", "id": "reaction_10784868", "reactome": "R-SCE-6811411", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784864", "species_10784385" ], "products": [ "species_10784866" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "species_29438", "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "species_29420", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438" ] }, "reaction_10785080": { "compartment": "compartment_12045", "id": "reaction_10785080", "reactome": "R-SCE-6811427", "name": "COPI vesicle uncoating at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785078" ], "products": [ "species_10785076", "species_10784438", "species_10784980", "species_10785042", "species_10781345" ], "modifiers": [], "additional_components": [ "P32803", "YGL200C", "P53198", "YGL002W", "P39704", "YAL007C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P41810", "YDR238C", "P22214", "YLR268W", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P33891", "YGL145W", "P38819", "YHR110W", "P43621", "YFR051C", "P53146", "YGL098W", "P28791", "YDR498C", "P53337", "YGR284C", "P41834", "YOR075W", "P53600", "YPL010W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "Q12403", "YDL018C", "P53847", "YNL258C", "P32074", "YNL287W", "P41811", "YGL137W", "P18414", "YBL040C", "P38819", "YHR110W", "P32803", "YGL200C", "P53198", "YGL002W", "P53337", "YGR284C", "P54837", "YML012W", "Q05359", "YAR002C-A", "P43621", "YFR051C", "P53600", "YPL010W", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P41810", "YDR238C", "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P22214", "YLR268W", "P38819", "YHR110W", "P32803", "YGL200C", "P53198", "YGL002W", "P39704", "YAL007C", "Q12403", "YDL018C", "P54837", "YML012W", "Q12450", "YOR016C", "Q05359", "YAR002C-A", "species_29420", "P01123", "YFL038C" ] }, "reaction_10784877": { "compartment": "compartment_20699", "id": "reaction_10784877", "reactome": "R-SCE-6811414", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10784866" ], "products": [ "species_10784870", "species_29420" ], "modifiers": [ [ "species_10784866", "catalyst" ] ], "additional_components": [ "species_29420", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "species_29420", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438" ] }, "reaction_10769704": { "compartment": "compartment_876", "id": "reaction_10769704", "reactome": "R-SCE-426130", "name": "SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113", "species_188972" ], "products": [ "species_83910", "species_352022" ], "modifiers": [ [ "species_10769701", "catalyst" ] ], "additional_components": [ "YBR235W" ] }, "reaction_10769699": { "compartment": "compartment_876", "id": "reaction_10769699", "reactome": "R-SCE-426086", "name": "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113", "species_188972", "species_74126" ], "products": [ "species_29804", "species_83910", "species_352022" ], "modifiers": [ [ "species_10769694", "catalyst" ] ], "additional_components": [ "YBR235W" ] }, "reaction_10774613": { "compartment": "compartment_70101", "id": "reaction_10774613", "reactome": "R-SCE-2534096", "name": "METAP1/2 demethylates GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774594" ], "products": [ "species_174390", "species_10774582" ], "modifiers": [ [ "species_10774610", "catalyst" ] ], "additional_components": [ "YER020W", "YER020W", "Q01662", "YLR244C", "P38174", "YBL091C", "species_880069" ] }, "reaction_10774654": { "compartment": "compartment_70101", "id": "reaction_10774654", "reactome": "R-SCE-2586748", "name": "GUCA binds Ca2+ to form GUCA:Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_10774640" ], "products": [ "species_10774652" ], "modifiers": [], "additional_components": [ "YDR373W", "species_74016", "Q06389", "YDR373W" ] }, "reaction_10774592": { "compartment": "compartment_70101", "id": "reaction_10774592", "reactome": "R-SCE-2534087", "name": "NMT1/2 transfer MYS to GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2534019", "species_10774582" ], "products": [ "species_76194", "species_10763522" ], "modifiers": [ [ "species_10774587", "catalyst" ] ], "additional_components": [ "YER020W", "YER020W", "YLR195C" ] }, "reaction_10763540": { "compartment": "compartment_2514888", "id": "reaction_10763540", "reactome": "R-SCE-74059", "name": "PDE6 hydrolyses cGMP to GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30991" ], "products": [ "species_113578" ], "modifiers": [ [ "species_10763537", "catalyst" ] ], "additional_components": [ "P06776", "YOR360C", "species_29438", "P10823", "YER020W" ] }, "reaction_10774322": { "compartment": "compartment_70101", "id": "reaction_10774322", "reactome": "R-SCE-2465940", "name": "atRAL is reduced to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_975622" ], "products": [ "species_29366", "species_2473607" ], "modifiers": [ [ "species_10774319", "catalyst" ] ], "additional_components": [ "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C" ] }, "reaction_10765352": { "compartment": "compartment_7660", "id": "reaction_10765352", "reactome": "R-SCE-156678", "name": "Activation of Cdc25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765340", "species_113592" ], "products": [ "species_29370", "species_10765343" ], "modifiers": [ [ "species_10765349", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "YMR001C" ] }, "reaction_10765477": { "compartment": "compartment_7660", "id": "reaction_10765477", "reactome": "R-SCE-162657", "name": "Inactivation of Myt1 kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10765469" ], "products": [ "species_113582", "species_10765472" ], "modifiers": [ [ "species_10765474", "catalyst" ] ], "additional_components": [ "YJL187C", "YJL187C", "YMR001C" ] }, "reaction_10771316": { "compartment": "compartment_70101", "id": "reaction_10771316", "reactome": "R-SCE-893616", "name": "glutamine + pyruvate => 2-oxoglutaramate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29398" ], "products": [ "species_893598", "species_29432" ], "modifiers": [ [ "species_10771307", "catalyst" ] ], "additional_components": [ "P47039", "YJL060W" ] }, "reaction_10781888": { "compartment": "compartment_5460", "id": "reaction_10781888", "reactome": "R-SCE-6783939", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113529", "species_113590" ], "products": [ "species_379717", "species_113526" ], "modifiers": [ [ "species_10781885", "catalyst" ] ], "additional_components": [ "P32263", "YER023W" ] }, "reaction_10761570": { "compartment": "compartment_5460", "id": "reaction_10761570", "reactome": "R-SCE-70664", "name": "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113529", "species_113590" ], "products": [ "species_379717", "species_113526" ], "modifiers": [ [ "species_10761567", "catalyst" ] ], "additional_components": [ "P32263", "YER023W" ] }, "reaction_10761572": { "compartment": "compartment_5460", "id": "reaction_10761572", "reactome": "R-SCE-70666", "name": "glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31339", "species_113552" ], "products": [ "species_113594", "species_113585" ], "modifiers": [ [ "species_10761557", "catalyst" ] ], "additional_components": [ "P07991", "YLR438W" ] }, "reaction_10771117": { "compartment": "compartment_5460", "id": "reaction_10771117", "reactome": "R-SCE-508040", "name": "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_113552", "species_113529", "species_113593" ], "products": [ "species_31339", "species_113548", "species_113563", "species_113581" ], "modifiers": [ [ "species_10771114", "catalyst" ] ], "additional_components": [ "P54885", "YOR323C" ] }, "reaction_10781895": { "compartment": "compartment_70101", "id": "reaction_10781895", "reactome": "R-SCE-6783955", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_35305" ], "products": [ "species_29366", "species_113538" ], "modifiers": [ [ "species_10781892", "catalyst" ] ], "additional_components": [ "P32263", "YER023W" ] }, "reaction_10761527": { "compartment": "compartment_70101", "id": "reaction_10761527", "reactome": "R-SCE-70606", "name": "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_31633" ], "products": [ "species_29370", "species_29472", "species_29372" ], "modifiers": [ [ "species_10761524", "catalyst" ] ], "additional_components": [ "P32288", "YPR035W" ] }, "reaction_10761529": { "compartment": "compartment_5460", "id": "reaction_10761529", "reactome": "R-SCE-70613", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113587" ], "products": [ "species_113594", "species_113553" ], "modifiers": [ [ "species_10761497", "catalyst" ] ], "additional_components": [ "Q01802", "YKL106W" ] }, "reaction_10789049": { "compartment": "compartment_7660", "id": "reaction_10789049", "reactome": "R-SCE-9671145", "name": "DKC1 binds SHQ1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765537", "species_10789045" ], "products": [ "species_10789047" ], "modifiers": [], "additional_components": [ "YLR175W", "YIL104C", "P33322", "YLR175W", "P40486", "YIL104C" ] }, "reaction_10769750": { "compartment": "compartment_876", "id": "reaction_10769750", "reactome": "R-SCE-427555", "name": "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648", "species_351626" ], "products": [ "species_70106", "species_174375" ], "modifiers": [ [ "species_10769747", "catalyst" ] ], "additional_components": [ "P53394", "YPR003C" ] }, "reaction_10766300": { "compartment": "compartment_70101", "id": "reaction_10766300", "reactome": "R-SCE-174392", "name": "PAPSS1,2 transfer SO4(2-) group to ATP to form APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174375", "species_113592" ], "products": [ "species_174370", "species_111294" ], "modifiers": [ [ "species_10766269", "catalyst" ] ], "additional_components": [ "YKL001C" ] }, "reaction_10766274": { "compartment": "compartment_70101", "id": "reaction_10766274", "reactome": "R-SCE-174389", "name": "PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174370", "species_113592" ], "products": [ "species_158471", "species_29370" ], "modifiers": [ [ "species_10766269", "catalyst" ] ], "additional_components": [ "YKL001C" ] }, "reaction_10778591": { "compartment": "compartment_7660", "id": "reaction_10778591", "reactome": "R-SCE-5661121", "name": "KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778271", "species_113671", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776818" ], "modifiers": [ [ "species_10776825", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YBR112C" ] }, "reaction_10778580": { "compartment": "compartment_7660", "id": "reaction_10778580", "reactome": "R-SCE-5661116", "name": "KDM5A-D demethylate Me3K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777406", "species_113671", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776782" ], "modifiers": [ [ "species_10776810", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03214", "YMR176W", "P47156", "YJR119C" ] }, "reaction_10775027": { "compartment": "compartment_7660", "id": "reaction_10775027", "reactome": "R-SCE-3214912", "name": "KDM1A, KDM1B demethylate MeK5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775017" ], "products": [ "species_10775019", "species_29478" ], "modifiers": [ [ "species_10775024", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YMR020W" ] }, "reaction_10778578": { "compartment": "compartment_7660", "id": "reaction_10778578", "reactome": "R-SCE-5661114", "name": "KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10778230", "species_113685" ], "products": [ "species_10776742", "species_159942", "species_159939", "species_29478" ], "modifiers": [ [ "species_10776754", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03833", "YDR096W", "P39956", "YER169W" ] }, "reaction_10778589": { "compartment": "compartment_7660", "id": "reaction_10778589", "reactome": "R-SCE-5661120", "name": "KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10776843", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776759" ], "modifiers": [ [ "species_10776777", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03833", "YDR096W", "P39956", "YER169W" ] }, "reaction_10776757": { "compartment": "compartment_7660", "id": "reaction_10776757", "reactome": "R-SCE-4722133", "name": "KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776742", "species_113671", "species_113685" ], "products": [ "species_10775019", "species_159942", "species_159939", "species_29478" ], "modifiers": [ [ "species_10776754", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03833", "YDR096W", "P39956", "YER169W" ] }, "reaction_10776780": { "compartment": "compartment_7660", "id": "reaction_10776780", "reactome": "R-SCE-4724279", "name": "KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10776759", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776761" ], "modifiers": [ [ "species_10776777", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03833", "YDR096W", "P39956", "YER169W" ] }, "reaction_10776813": { "compartment": "compartment_7660", "id": "reaction_10776813", "reactome": "R-SCE-4754181", "name": "KDM5A-D demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10776782" ], "products": [ "species_159942", "species_10775017", "species_159939", "species_29478" ], "modifiers": [ [ "species_10776810", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03214", "YMR176W", "P47156", "YJR119C" ] }, "reaction_10778593": { "compartment": "compartment_7660", "id": "reaction_10778593", "reactome": "R-SCE-5661123", "name": "KDM1A, KDM1B demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776782" ], "products": [ "species_10775017", "species_29478" ], "modifiers": [ [ "species_10775024", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YMR020W" ] }, "reaction_10776830": { "compartment": "compartment_7660", "id": "reaction_10776830", "reactome": "R-SCE-4754187", "name": "KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10776818", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776823" ], "modifiers": [ [ "species_10776825", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YBR112C" ] }, "reaction_10770574": { "compartment": "compartment_7660", "id": "reaction_10770574", "reactome": "R-SCE-448955", "name": "Phosphorylation of MEF2 proteins by p38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10770541", "species_10770545" ], "products": [ "species_113582", "species_10770571" ], "modifiers": [ [ "species_10770545", "catalyst" ] ], "additional_components": [ "P38128", "YBR182C", "Q12224", "YPL089C", "P32485", "YLR113W", "P32485", "YLR113W", "P38128", "YBR182C", "Q12224", "YPL089C", "P32485", "YLR113W" ] }, "reaction_10769182": { "compartment": "compartment_17940", "id": "reaction_10769182", "reactome": "R-SCE-392749", "name": "Transport of L1 into endosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769180" ], "products": [ "species_10769180" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C" ] }, "reaction_10770284": { "compartment": "compartment_70101", "id": "reaction_10770284", "reactome": "R-SCE-445079", "name": "Phosphorylation of L1 by ERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10769180", "species_10764614" ], "products": [ "species_29370", "species_10770282" ], "modifiers": [ [ "species_10764614", "catalyst" ] ], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "YBL016W", "P16892", "YBL016W", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "YBL016W" ] }, "reaction_10764609": { "compartment": "compartment_70101", "id": "reaction_10764609", "reactome": "R-SCE-109860", "name": "MAP2K1 phosphorylates MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10764572" ], "products": [ "species_29370", "species_10764600" ], "modifiers": [ [ "species_10764572", "catalyst" ], [ "species_10764605", "inhibitor" ] ], "additional_components": [ "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "YDL159W" ] }, "reaction_10767247": { "compartment": "compartment_7660", "id": "reaction_10767247", "reactome": "R-SCE-198756", "name": "ERK1/2 phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767221", "species_29358" ], "products": [ "species_113582", "species_10767227" ], "modifiers": [ [ "species_10767244", "catalyst" ] ], "additional_components": [ "YBR028C", "YBR028C", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10764619": { "compartment": "compartment_70101", "id": "reaction_10764619", "reactome": "R-SCE-109862", "name": "MAP2K2 phosphorylates MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764582", "species_113592" ], "products": [ "species_29370", "species_10764616" ], "modifiers": [ [ "species_10764582", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "P06784", "YDL159W", "P16892", "YBL016W", "P06784", "YDL159W", "P16892", "YBL016W", "P06784", "YDL159W" ] }, "reaction_10766423": { "compartment": "compartment_7660", "id": "reaction_10766423", "reactome": "R-SCE-176956", "name": "Formation of GINS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766419", "species_10766414", "species_10766404", "species_10766409" ], "products": [ "species_10766421" ], "modifiers": [], "additional_components": [ "YDR489W", "YOL146W", "YDR013W", "YJL072C", "Q12488", "YDR013W", "Q03406", "YDR489W", "P40359", "YJL072C", "Q12146", "YOL146W" ] }, "reaction_10787208": { "compartment": "compartment_12045", "id": "reaction_10787208", "reactome": "R-SCE-8941701", "name": "UGT1A10 transfers GlcA from UDP-GlcA to GCTN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8941723", "species_174384" ], "products": [ "species_158602", "species_8941725" ], "modifiers": [ [ "species_10765445", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10772692": { "compartment": "compartment_70101", "id": "reaction_10772692", "reactome": "R-SCE-1247910", "name": "CNDP2:2Mn2+ dimer hydrolyses CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1247904", "species_29356" ], "products": [ "species_29424", "species_111707" ], "modifiers": [ [ "species_10772689", "catalyst" ] ], "additional_components": [ "species_113527", "P43616", "YFR044C" ] }, "reaction_10788717": { "compartment": "compartment_17957", "id": "reaction_10788717", "reactome": "R-SCE-9632038", "name": "UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159160", "species_174384" ], "products": [ "species_158602", "species_159149" ], "modifiers": [ [ "species_10788714", "catalyst" ] ], "additional_components": [ "Q06321", "YLR189C" ] }, "reaction_10765464": { "compartment": "compartment_17957", "id": "reaction_10765464", "reactome": "R-SCE-159194", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159151", "species_174384" ], "products": [ "species_159160", "species_158602" ], "modifiers": [ [ "species_10765459", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10766342": { "compartment": "compartment_17957", "id": "reaction_10766342", "reactome": "R-SCE-174916", "name": "Formation of N-glucuronides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174384", "species_174932" ], "products": [ "species_158602", "species_174918" ], "modifiers": [ [ "species_10765459", "catalyst" ] ], "additional_components": [ "CHEBI:41774", "CHEBI:17688", "CHEBI:32663", "CHEBI:63860", "YLR189C" ] }, "reaction_10766297": { "compartment": "compartment_70101", "id": "reaction_10766297", "reactome": "R-SCE-174391", "name": "MAT1A multimers transfer Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_174390", "species_29356" ], "products": [ "species_111294", "species_71284", "species_29372" ], "modifiers": [ [ "species_10766294", "catalyst" ] ], "additional_components": [ "P19358", "YDR502C", "species_74126", "species_109496", "P10659", "YLR180W" ] }, "reaction_10765462": { "compartment": "compartment_17957", "id": "reaction_10765462", "reactome": "R-SCE-159179", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159160", "species_174384" ], "products": [ "species_158602", "species_159149" ], "modifiers": [ [ "species_10765459", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10766310": { "compartment": "compartment_70101", "id": "reaction_10766310", "reactome": "R-SCE-174394", "name": "GSS:Mg2+ dimer synthesizes GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_174393", "species_113592" ], "products": [ "species_29370", "species_29450", "species_29372" ], "modifiers": [ [ "species_10766307", "catalyst" ], [ "species_29450", "inhibitor" ] ], "additional_components": [ "Q08220", "YOL049W", "species_109496" ] }, "reaction_10766322": { "compartment": "compartment_70101", "id": "reaction_10766322", "reactome": "R-SCE-174401", "name": "AHCY:NAD+ tetramer hydrolyses AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71285", "species_29356" ], "products": [ "species_174369", "species_83909" ], "modifiers": [ [ "species_10766319", "catalyst" ] ], "additional_components": [ "P39954", "YER043C", "species_113526" ] }, "reaction_10787391": { "compartment": "compartment_876", "id": "reaction_10787391", "reactome": "R-SCE-8943279", "name": "GGT dimers hydrolyse GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1247892", "species_109276" ], "products": [ "species_210382", "species_1247934" ], "modifiers": [ [ "species_10777790", "catalyst" ] ], "additional_components": [ "Q05902", "YLR299W" ] }, "reaction_10781250": { "compartment": "compartment_17957", "id": "reaction_10781250", "reactome": "R-SCE-5693724", "name": "ESD dimer hydrolyses S-FGSH to GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_5693723" ], "products": [ "species_158543", "species_194712" ], "modifiers": [ [ "species_10781247", "catalyst" ] ], "additional_components": [ "P40363", "YJL068C" ] }, "reaction_10783821": { "compartment": "compartment_70101", "id": "reaction_10783821", "reactome": "R-SCE-6800149", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6806829", "species_71284" ], "products": [ "species_6800127", "species_71285" ], "modifiers": [ [ "species_10783815", "catalyst" ] ], "additional_components": [ "P53738", "TRM112", "Q03920", "YDR140W" ] }, "reaction_10772702": { "compartment": "compartment_70101", "id": "reaction_10772702", "reactome": "R-SCE-1247935", "name": "OPLAH hydrolyses OPRO to L-Glu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1247942", "species_29356" ], "products": [ "species_29370", "species_29404", "species_29372" ], "modifiers": [ [ "species_10772699", "catalyst" ] ], "additional_components": [ "P28273", "YKL215C" ] }, "reaction_10788719": { "compartment": "compartment_17957", "id": "reaction_10788719", "reactome": "R-SCE-9632039", "name": "UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159151", "species_174384" ], "products": [ "species_159160", "species_158602" ], "modifiers": [ [ "species_10765441", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10761138": { "compartment": "compartment_70101", "id": "reaction_10761138", "reactome": "R-SCE-70286", "name": "UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29494", "species_29548" ], "products": [ "species_29410", "species_111294" ], "modifiers": [ [ "species_10761135", "catalyst" ] ], "additional_components": [ "P32861", "YKL035W" ] }, "reaction_10781969": { "compartment": "compartment_70101", "id": "reaction_10781969", "reactome": "R-SCE-6785928", "name": "CHAC1,2 cleaves GSH to OPRO and CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450" ], "products": [ "species_1247904", "species_1247942" ], "modifiers": [ [ "species_10781964", "catalyst" ] ], "additional_components": [ "YER163C" ] }, "reaction_10778676": { "compartment": "compartment_70101", "id": "reaction_10778676", "reactome": "R-SCE-5668545", "name": "NIK autophosphorylates on T559", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769138", "species_113592" ], "products": [ "species_29370", "species_10778673" ], "modifiers": [ [ "species_10769138", "catalyst" ] ], "additional_components": [ "YCR073C", "YCR073C", "YCR073C" ] }, "reaction_10778670": { "compartment": "compartment_70101", "id": "reaction_10778670", "reactome": "R-SCE-5668520", "name": "26Sproteasome degrades K48polyUb-NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778668" ], "products": [], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "YCR073C", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10784295": { "compartment": "compartment_70101", "id": "reaction_10784295", "reactome": "R-SCE-6805811", "name": "Release of SEPT4 from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784279" ], "products": [ "species_10784293" ], "modifiers": [], "additional_components": [ "P32457", "YLR314C", "Q07657", "YDL225W", "Q04921", "YDR218C", "P32468", "YHR107C", "P41901", "YGR059W", "P32458", "YJR076C", "P32457", "YLR314C", "Q07657", "YDL225W", "Q04921", "YDR218C", "P32468", "YHR107C", "P41901", "YGR059W", "P32458", "YJR076C" ] }, "reaction_10765222": { "compartment": "compartment_17906", "id": "reaction_10765222", "reactome": "R-SCE-114284", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765220" ], "products": [ "species_10765214" ], "modifiers": [], "additional_components": [ "P00045", "YEL039C", "P00044", "YJR048W", "P00045", "YEL039C", "P00044", "YJR048W" ] }, "reaction_10764147": { "compartment": "compartment_7660", "id": "reaction_10764147", "reactome": "R-SCE-75891", "name": "Abortive Initiation After Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764145" ], "products": [ "species_10763503", "species_75897", "species_10763293", "species_10762312" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P36100", "YKL028W", "P22139", "RPB10", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P06839", "RAD3", "P36100", "YKL028W", "P36145", "YKR062W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764072": { "compartment": "compartment_7660", "id": "reaction_10764072", "reactome": "R-SCE-75862", "name": "Fall Back to Closed Pre-initiation Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764062" ], "products": [ "species_10764070" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10765186": { "compartment": "compartment_7660", "id": "reaction_10765186", "reactome": "R-SCE-112434", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764352", "species_10764976" ], "products": [ "species_10764978" ], "modifiers": [], "additional_components": [ "YML010W", "YGR063C", "P27692", "YML010W", "P32914", "YGR063C" ] }, "reaction_10765190": { "compartment": "compartment_7660", "id": "reaction_10765190", "reactome": "R-SCE-113409", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765001" ], "products": [ "species_10765001" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P27692", "YML010W", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P32914", "YGR063C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10", "P41896", "YGR005C", "P20434", "RPB5", "P27692", "YML010W", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P32914", "YGR063C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10763507": { "compartment": "compartment_7660", "id": "reaction_10763507", "reactome": "R-SCE-73946", "name": "Abortive initiation after formation of the first phosphodiester bond", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763505" ], "products": [ "species_109877", "species_10763503", "species_10763491", "species_10763293", "species_10762312", "species_10763417", "species_10763422" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P36100", "YKL028W", "P36145", "YKR062W", "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P32774", "YKL058W", "P32773", "YOR194C", "YPR086W" ] }, "reaction_10764060": { "compartment": "compartment_7660", "id": "reaction_10764060", "reactome": "R-SCE-75856", "name": "Abortive Initiation Before Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764058" ], "products": [ "species_110068", "species_10763503", "species_10763491", "species_10763293", "species_10762312", "species_10763417", "species_10763422" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P36100", "YKL028W", "P36145", "YKR062W", "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P32774", "YKL058W", "P32773", "YOR194C", "YPR086W" ] }, "reaction_10765192": { "compartment": "compartment_7660", "id": "reaction_10765192", "reactome": "R-SCE-113411", "name": "2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765164" ], "products": [ "species_10765168" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765184": { "compartment": "compartment_7660", "id": "reaction_10765184", "reactome": "R-SCE-112430", "name": "Formation of P-TEFb complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765028", "species_10765006" ], "products": [ "species_10765030" ], "modifiers": [], "additional_components": [ "Q05949", "YLR226W", "P46962", "YJL006C", "YKL139W", "Q05949", "YLR226W", "Q03957", "YKL139W", "P46962", "YJL006C" ] }, "reaction_10765170": { "compartment": "compartment_7660", "id": "reaction_10765170", "reactome": "R-SCE-112392", "name": "Resumption of elongation after recovery from pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765168" ], "products": [ "species_10765164" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765198": { "compartment": "compartment_7660", "id": "reaction_10765198", "reactome": "R-SCE-113414", "name": "7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765164" ], "products": [ "species_10765164" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765182": { "compartment": "compartment_7660", "id": "reaction_10765182", "reactome": "R-SCE-112429", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765097", "species_10765092" ], "products": [ "species_10765099" ], "modifiers": [], "additional_components": [ "YGL207W", "YML069W", "P32558", "YGL207W", "Q04636", "YML069W" ] }, "reaction_10765174": { "compartment": "compartment_7660", "id": "reaction_10765174", "reactome": "R-SCE-112395", "name": "Abortive termination of elongation after arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765164" ], "products": [ "species_10765172" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765196": { "compartment": "compartment_7660", "id": "reaction_10765196", "reactome": "R-SCE-113413", "name": "TFIIS-mediated recovery of elongation from arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765164" ], "products": [ "species_10765164" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10761589": { "compartment": "compartment_70101", "id": "reaction_10761589", "reactome": "R-SCE-70692", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498" ], "products": [ "species_29610", "species_113528" ], "modifiers": [ [ "species_10761586", "catalyst" ] ], "additional_components": [ "YKL184W" ] }, "reaction_10768335": { "compartment": "compartment_70101", "id": "reaction_10768335", "reactome": "R-SCE-350598", "name": "Arginine<=>Agmatine+CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468" ], "products": [ "species_113528", "species_351164" ], "modifiers": [ [ "species_10768332", "catalyst" ] ], "additional_components": [ "YKL184W" ] }, "reaction_10768411": { "compartment": "compartment_70101", "id": "reaction_10768411", "reactome": "R-SCE-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353113", "species_29610" ], "products": [ "species_353106", "species_204635" ], "modifiers": [ [ "species_10768408", "catalyst" ] ], "additional_components": [ "YPR069C" ] }, "reaction_10768403": { "compartment": "compartment_70101", "id": "reaction_10768403", "reactome": "R-SCE-351208", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_204635", "species_76183" ], "products": [ "species_76194", "species_353555" ], "modifiers": [ [ "species_10768398", "catalyst" ] ], "additional_components": [ "Q06592", "YPR193C", "P39979", "YEL066W" ] }, "reaction_10768419": { "compartment": "compartment_70101", "id": "reaction_10768419", "reactome": "R-SCE-351222", "name": "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284" ], "products": [ "species_353113", "species_113528" ], "modifiers": [ [ "species_10768416", "catalyst" ] ], "additional_components": [ "YOL052C" ] }, "reaction_10768401": { "compartment": "compartment_70101", "id": "reaction_10768401", "reactome": "R-SCE-351207", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353560", "species_76183" ], "products": [ "species_76194", "species_353575" ], "modifiers": [ [ "species_10768398", "catalyst" ] ], "additional_components": [ "Q06592", "YPR193C", "P39979", "YEL066W" ] }, "reaction_10778699": { "compartment": "compartment_70101", "id": "reaction_10778699", "reactome": "R-SCE-5671737", "name": "p-T774-PKN1 binds CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765340", "species_10778027" ], "products": [ "species_10778697" ], "modifiers": [], "additional_components": [ "YMR036C", "YBL105C", "P23748", "YMR036C", "P24583", "YBL105C" ] }, "reaction_10778693": { "compartment": "compartment_70101", "id": "reaction_10778693", "reactome": "R-SCE-5668932", "name": "PAK2 phosphorylates myosin regulatory light chain (MRLC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778684", "species_113592" ], "products": [ "species_29370", "species_10778690" ], "modifiers": [ [ "species_10778151", "catalyst" ] ], "additional_components": [ "P08964", "YHR023W", "Q06580", "YPR188C", "P53141", "YGL106W", "P08964", "YHR023W", "Q06580", "YPR188C", "P53141", "YGL106W", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W" ] }, "reaction_10778117": { "compartment": "compartment_70101", "id": "reaction_10778117", "reactome": "R-SCE-5626469", "name": "GTP-bound RAC1 and CDC42 bind IQGAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778113", "species_10768894" ], "products": [ "species_10778115" ], "modifiers": [], "additional_components": [ "Q12280", "YPL242C", "species_29438", "P19073", "YLR229C", "Q12280", "YPL242C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10778702": { "compartment": "compartment_70101", "id": "reaction_10778702", "reactome": "R-SCE-5671749", "name": "p-T774-PKN1 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778697", "species_113592" ], "products": [ "species_29370", "species_10763798", "species_10778027" ], "modifiers": [ [ "species_10778697", "catalyst" ] ], "additional_components": [ "P23748", "YMR036C", "P24583", "YBL105C", "YMR036C", "YBL105C", "P23748", "YMR036C", "P24583", "YBL105C" ] }, "reaction_10778091": { "compartment": "compartment_7660", "id": "reaction_10778091", "reactome": "R-SCE-5625797", "name": "KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10778076" ], "products": [ "species_159942", "species_159939", "species_10776769", "species_29478", "species_10778088" ], "modifiers": [ [ "species_10778076", "catalyst" ] ], "additional_components": [ "Q03833", "YDR096W", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P39956", "YER169W", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "Q03833", "YDR096W", "P39956", "YER169W", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "Q03833", "YDR096W", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P39956", "YER169W", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117" ] }, "reaction_10778074": { "compartment": "compartment_7660", "id": "reaction_10778074", "reactome": "R-SCE-5625784", "name": "PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778057", "species_29358" ], "products": [ "species_113582", "species_10778071" ], "modifiers": [ [ "species_10778057", "catalyst" ] ], "additional_components": [ "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117" ] }, "reaction_10778123": { "compartment": "compartment_70101", "id": "reaction_10778123", "reactome": "R-SCE-5626507", "name": "IQGAPs bind F-actin, which is inhibited by calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778115", "species_10773881" ], "products": [ "species_10778119" ], "modifiers": [ [ "species_10778121", "inhibitor" ] ], "additional_components": [ "Q12280", "YPL242C", "species_29438", "P19073", "YLR229C", "P60010", "YFL039C", "species_113592", "P60010", "YFL039C", "Q12280", "YPL242C", "species_113592", "species_29438", "P19073", "YLR229C", "P06787", "YBR109C", "Q12280", "YPL242C", "species_74016", "species_29438", "P19073", "YLR229C" ] }, "reaction_10778078": { "compartment": "compartment_7660", "id": "reaction_10778078", "reactome": "R-SCE-5625796", "name": "Demethylase KDM4C binds KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778071", "species_10776769" ], "products": [ "species_10778076" ], "modifiers": [], "additional_components": [ "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "Q03833", "YDR096W", "P39956", "YER169W", "Q03833", "YDR096W", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P39956", "YER169W", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117" ] }, "reaction_10787831": { "compartment": "compartment_70101", "id": "reaction_10787831", "reactome": "R-SCE-8981931", "name": "RAC1 and CDC42 activate PAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768988", "species_10768894" ], "products": [ "species_10768986", "species_10778133" ], "modifiers": [], "additional_components": [ "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "P48562", "YNL298W", "Q03497", "YHL007C", "species_29438", "Q12469", "YOL113W", "P19073", "YLR229C" ] }, "reaction_10778020": { "compartment": "compartment_876", "id": "reaction_10778020", "reactome": "R-SCE-5623622", "name": "RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778012", "species_10769305" ], "products": [ "species_10778018" ], "modifiers": [], "additional_components": [ "YBL105C", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_29438" ] }, "reaction_10778160": { "compartment": "compartment_70101", "id": "reaction_10778160", "reactome": "R-SCE-5627775", "name": "Autophosphorylation of PAK1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10778137" ], "products": [ "species_29370", "species_10778157", "species_10768894" ], "modifiers": [ [ "species_10778137", "catalyst" ] ], "additional_components": [ "P48562", "YNL298W", "Q03497", "YHL007C", "species_29438", "Q12469", "YOL113W", "P19073", "YLR229C", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "Q03497", "YHL007C", "species_29438", "Q12469", "YOL113W", "P19073", "YLR229C" ] }, "reaction_10774032": { "compartment": "compartment_70101", "id": "reaction_10774032", "reactome": "R-SCE-2029456", "name": "RAC1 and CDC42 activate PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768972", "species_10768894" ], "products": [ "species_10768970", "species_10774023" ], "modifiers": [], "additional_components": [ "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C", "YHL007C", "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10787829": { "compartment": "compartment_70101", "id": "reaction_10787829", "reactome": "R-SCE-8981926", "name": "RAC1 and CDC42 activate PAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768992", "species_10768894" ], "products": [ "species_10768990", "species_10778135" ], "modifiers": [], "additional_components": [ "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C", "YHL007C", "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10778126": { "compartment": "compartment_876", "id": "reaction_10778126", "reactome": "R-SCE-5626549", "name": "IQGAPs bind CALM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778115", "species_10767596" ], "products": [ "species_10778121" ], "modifiers": [], "additional_components": [ "Q12280", "YPL242C", "species_29438", "P19073", "YLR229C", "P06787", "YBR109C", "species_74016", "P06787", "YBR109C", "Q12280", "YPL242C", "species_74016", "species_29438", "P19073", "YLR229C" ] }, "reaction_10788712": { "compartment": "compartment_70101", "id": "reaction_10788712", "reactome": "R-SCE-9626817", "name": "PKC phosphorylates NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10788701" ], "products": [ "species_10788710", "species_29370" ], "modifiers": [ [ "species_10777257", "catalyst" ] ], "additional_components": [ "P29366", "YBR200W", "P22696", "YJR017C", "P29366", "YBR200W", "P22696", "YJR017C", "YBL105C" ] }, "reaction_10774058": { "compartment": "compartment_70101", "id": "reaction_10774058", "reactome": "R-SCE-2029473", "name": "Branching and elongation of mother and daughter filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774056", "species_10767714" ], "products": [ "species_10773926" ], "modifiers": [], "additional_components": [ "P60010", "YFL039C", "P40518", "YIL062C", "P53731", "YNR035C", "species_29370", "species_113592", "P33204", "YKL013C", "P32381", "YDL029W", "P47117", "YJR065C", "P38328", "YBR234C", "Q05933", "YLR370C", "P60010", "YFL039C", "species_113592", "P40518", "YIL062C", "P60010", "YFL039C", "P53731", "YNR035C", "P33204", "YKL013C", "species_113592", "P32381", "YDL029W", "P47117", "YJR065C", "P38328", "YBR234C", "Q05933", "YLR370C" ] }, "reaction_10778036": { "compartment": "compartment_70101", "id": "reaction_10778036", "reactome": "R-SCE-5623667", "name": "PDPK1 phosphorylates PKN1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10778022" ], "products": [ "species_29370", "species_10764515", "species_10778027", "species_10769305" ], "modifiers": [ [ "species_10778022", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_179838", "species_29438", "Q12236", "YOL100W", "species_179838", "Q12236", "YOL100W", "YBL105C", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_179838", "species_29438", "Q12236", "YOL100W" ] }, "reaction_10782731": { "compartment": "compartment_1222693", "id": "reaction_10782731", "reactome": "R-SCE-6798174", "name": "PIK3C3:PIK3R4 phosphorylates PI to PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524165" ], "products": [ "species_29370", "species_1629751" ], "modifiers": [ [ "species_10782728", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W" ] }, "reaction_10778024": { "compartment": "compartment_876", "id": "reaction_10778024", "reactome": "R-SCE-5623632", "name": "RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764515", "species_10778018" ], "products": [ "species_10778022" ], "modifiers": [], "additional_components": [ "species_179838", "Q12236", "YOL100W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_179838", "species_29438", "Q12236", "YOL100W" ] }, "reaction_10767642": { "compartment": "compartment_70101", "id": "reaction_10767642", "reactome": "R-SCE-202127", "name": "eNOS synthesizes NO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29468", "species_29368" ], "products": [ "species_29366", "species_202124", "species_29968" ], "modifiers": [ [ "species_10767639", "catalyst" ], [ "species_5693375", "inhibitor" ] ], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "species_29870", "species_113596", "P11792", "YHR205W" ] }, "reaction_10777290": { "compartment": "compartment_876", "id": "reaction_10777290", "reactome": "R-SCE-5218821", "name": "PDK1 phosphorylates PKC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10765240" ], "products": [ "species_29370", "species_10777257" ], "modifiers": [ [ "species_10764513", "catalyst" ] ], "additional_components": [ "YBL105C", "YBL105C", "YOL100W" ] }, "reaction_10777285": { "compartment": "compartment_70101", "id": "reaction_10777285", "reactome": "R-SCE-5218813", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_112275", "species_10777268" ], "products": [ "species_10777283" ], "modifiers": [], "additional_components": [ "YBL105C", "species_112275", "P24583", "YBL105C", "species_74016" ] }, "reaction_10774274": { "compartment": "compartment_876", "id": "reaction_10774274", "reactome": "R-SCE-2317314", "name": "AKT binds PDPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767085", "species_10764515" ], "products": [ "species_10767087" ], "modifiers": [], "additional_components": [ "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "species_179838", "Q12236", "YOL100W", "P12688", "YKL126W", "species_179838", "Q12236", "YOL100W", "P11792", "YHR205W" ] }, "reaction_10777281": { "compartment": "compartment_70101", "id": "reaction_10777281", "reactome": "R-SCE-5218805", "name": "PKC autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10777257" ], "products": [ "species_29370", "species_10777268" ], "modifiers": [ [ "species_10777257", "catalyst" ] ], "additional_components": [ "YBL105C", "YBL105C", "YBL105C" ] }, "reaction_10767108": { "compartment": "compartment_70101", "id": "reaction_10767108", "reactome": "R-SCE-198270", "name": "PDPK1 phosphorylates AKT at T308", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10767087" ], "products": [ "species_29370", "species_10764515", "species_10767105" ], "modifiers": [ [ "species_10767087", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "species_179838", "Q12236", "YOL100W", "P11792", "YHR205W", "species_179838", "Q12236", "YOL100W", "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "Q12236", "YOL100W", "P11792", "YHR205W" ] }, "reaction_10766460": { "compartment": "compartment_70101", "id": "reaction_10766460", "reactome": "R-SCE-187688", "name": "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10766440" ], "products": [ "species_29370", "species_10766447" ], "modifiers": [ [ "species_10766457", "catalyst" ] ], "additional_components": [ "YKL171W", "YKL171W", "P32485", "YLR113W", "species_109496" ] }, "reaction_10767654": { "compartment": "compartment_70101", "id": "reaction_10767654", "reactome": "R-SCE-202137", "name": "AKT1 binds eNOS complex via HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767610", "species_10767095" ], "products": [ "species_10767618" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "P02829", "YPL240C", "species_74016", "species_73524", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "species_113596", "P12688", "YKL126W", "P11792", "YHR205W", "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_74016", "species_73524", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "P11792", "YHR205W", "species_113596" ] }, "reaction_10777296": { "compartment": "compartment_876", "id": "reaction_10777296", "reactome": "R-SCE-5218823", "name": "PKC phosphorylates sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10769088" ], "products": [ "species_29370", "species_10777293" ], "modifiers": [ [ "species_10777283", "catalyst" ] ], "additional_components": [ "YLR260W", "YLR260W", "species_112275", "P24583", "YBL105C", "species_74016" ] }, "reaction_10773346": { "compartment": "compartment_70101", "id": "reaction_10773346", "reactome": "R-SCE-1497784", "name": "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_10767635" ], "products": [ "species_10767639" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "species_29870", "P15108", "YMR186W", "species_113596", "P11792", "YHR205W", "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "species_29870", "species_113596", "P11792", "YHR205W" ] }, "reaction_10767637": { "compartment": "compartment_70101", "id": "reaction_10767637", "reactome": "R-SCE-202111", "name": "AKT1 phosphorylates eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767618", "species_113592" ], "products": [ "species_29370", "species_10767635" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_74016", "species_73524", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "P11792", "YHR205W", "species_113596", "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "species_29870", "P15108", "YMR186W", "species_113596", "P11792", "YHR205W" ] }, "reaction_10767219": { "compartment": "compartment_70101", "id": "reaction_10767219", "reactome": "R-SCE-198640", "name": "TORC2 (mTOR) phosphorylates AKT at S473", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767182", "species_113592" ], "products": [ "species_29370", "species_10767085" ], "modifiers": [ [ "species_10767216", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "Q08236", "YOL078W", "P32600", "YKL203C", "P41318", "YNL006W", "P40061", "YER093C", "P38346", "YBR270C", "P47041", "YJL058C" ] }, "reaction_10772766": { "compartment": "compartment_876", "id": "reaction_10772766", "reactome": "R-SCE-1299318", "name": "Activation of TASK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772763", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10766256": { "compartment": "compartment_70101", "id": "reaction_10766256", "reactome": "R-SCE-174124", "name": "Dephosphorylation of phospho-Cdh1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766246", "species_29356" ], "products": [ "species_10766234", "species_111294" ], "modifiers": [ [ "species_10766253", "catalyst" ] ], "additional_components": [ "YGL003C", "YGL003C", "Q00684", "YFR028C" ] }, "reaction_10769735": { "compartment": "compartment_7660", "id": "reaction_10769735", "reactome": "R-SCE-427514", "name": "eNoSC deacetylates histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769718", "species_427523" ], "products": [ "species_10768101", "species_427498", "species_427497" ], "modifiers": [ [ "species_10769732", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P06700", "YDL042C", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P38961", "YDR083W", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10769738": { "compartment": "compartment_7660", "id": "reaction_10769738", "reactome": "R-SCE-427527", "name": "eNoSC dimethylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768101", "species_77087" ], "products": [ "species_77502", "species_10763784" ], "modifiers": [ [ "species_10769732", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P06700", "YDL042C", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P38961", "YDR083W", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10765828": { "compartment": "compartment_5460", "id": "reaction_10765828", "reactome": "R-SCE-164840", "name": "ADP and Pi bind to ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_10765816" ], "products": [ "species_10765818" ], "modifiers": [], "additional_components": [ "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P30902", "YKL016C", "species_29370", "P21306", "YPL271W", "P38077", "YBR039W", "P07251", "ATP1", "P00854", "Q0085", "species_29372", "P00830", "ATP2", "P61829", "OLI1", "P05626", "YPL078C", "Q12165", "YDL004W", "P09457", "YDR298C", "Q12233", "YPR020W" ] }, "reaction_10765823": { "compartment": "compartment_5460", "id": "reaction_10765823", "reactome": "R-SCE-164832", "name": "ATPase synthesizes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765818" ], "products": [ "species_113521", "species_10765820" ], "modifiers": [ [ "species_10765818", "catalyst" ] ], "additional_components": [ "P24814", "YJR090C", "P30902", "YKL016C", "species_29370", "P21306", "YPL271W", "P38077", "YBR039W", "P07251", "ATP1", "P00854", "Q0085", "species_29372", "P00830", "ATP2", "P61829", "OLI1", "P05626", "YPL078C", "Q12165", "YDL004W", "P09457", "YDR298C", "Q12233", "YPR020W", "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "species_113592", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P30902", "YKL016C", "species_29370", "P21306", "YPL271W", "P38077", "YBR039W", "P07251", "ATP1", "P00854", "Q0085", "species_29372", "P00830", "ATP2", "P61829", "OLI1", "P05626", "YPL078C", "Q12165", "YDL004W", "P09457", "YDR298C", "Q12233", "YPR020W" ] }, "reaction_10765826": { "compartment": "compartment_5460", "id": "reaction_10765826", "reactome": "R-SCE-164834", "name": "Enzyme-bound ATP is released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163953", "species_10765820" ], "products": [ "species_113529", "species_113593", "species_10765816" ], "modifiers": [ [ "species_10765820", "catalyst" ] ], "additional_components": [ "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "species_113592", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "species_113592", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W" ] }, "reaction_10783791": { "compartment": "compartment_70101", "id": "reaction_10783791", "reactome": "R-SCE-6799545", "name": "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6799540", "species_29356" ], "products": [ "species_429579", "species_6799543" ], "modifiers": [ [ "species_10783788", "catalyst" ] ], "additional_components": [ "species_158417", "P22855", "YGL156W" ] }, "reaction_10765881": { "compartment": "compartment_70101", "id": "reaction_10765881", "reactome": "R-SCE-165766", "name": "Phosphorylation and activation of eIF4G by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762672", "species_113592" ], "products": [ "species_29370", "species_10765879" ], "modifiers": [ [ "species_10765848", "catalyst" ] ], "additional_components": [ "P39936", "YGL049C", "P39935", "YGR162W", "P39936", "YGL049C", "P39935", "YGR162W", "YBR028C" ] }, "reaction_10765867": { "compartment": "compartment_70101", "id": "reaction_10765867", "reactome": "R-SCE-165726", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10762517" ], "products": [ "species_29370", "species_10765864" ], "modifiers": [ [ "species_10765848", "catalyst" ] ], "additional_components": [ "P0CX37", "RPS6A", "P0CX38", "RPS6B", "P0CX37", "RPS6A", "P0CX38", "RPS6B", "YBR028C" ] }, "reaction_10789075": { "compartment": "compartment_70101", "id": "reaction_10789075", "reactome": "R-SCE-9679044", "name": "FKBP1A binds sirolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678687", "species_10789071" ], "products": [ "species_10789073" ], "modifiers": [], "additional_components": [ "YNL135C", "species_9678687", "P20081", "YNL135C" ] }, "reaction_10770295": { "compartment": "compartment_876", "id": "reaction_10770295", "reactome": "R-SCE-445714", "name": "Aquaporin-3 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10770292", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10789035": { "compartment": "compartment_70101", "id": "reaction_10789035", "reactome": "R-SCE-9668389", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789031", "species_10771525" ], "products": [ "species_10789033" ], "modifiers": [], "additional_components": [ "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "P39955", "YER047C", "Q04272", "YMR077C", "P53843", "YNL265C", "YPR173C", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P52917", "YPR173C", "P36108", "YKL002W", "P39955", "YER047C", "Q04272", "YMR077C", "P53843", "YNL265C" ] }, "reaction_10789037": { "compartment": "compartment_70101", "id": "reaction_10789037", "reactome": "R-SCE-9668405", "name": "SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789019", "species_10789029" ], "products": [ "species_10789031" ], "modifiers": [], "additional_components": [ "YER047C", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "Q04272", "YMR077C", "P53843", "YNL265C", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "P39955", "YER047C", "Q04272", "YMR077C", "P53843", "YNL265C" ] }, "reaction_10789040": { "compartment": "compartment_70101", "id": "reaction_10789040", "reactome": "R-SCE-9668419", "name": "SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768744", "species_113592", "species_29356" ], "products": [ "species_29370", "species_10768740", "species_29372" ], "modifiers": [ [ "species_10789031", "catalyst" ] ], "additional_components": [ "species_29420", "P09734", "YML124C", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "species_29420", "P09734", "YML124C", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "P39955", "YER047C", "Q04272", "YMR077C", "P53843", "YNL265C" ] }, "reaction_10786014": { "compartment": "compartment_876", "id": "reaction_10786014", "reactome": "R-SCE-8855130", "name": "VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786004" ], "products": [ "species_10786012" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "P09232", "YEL060C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P09232", "YEL060C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C" ] }, "reaction_10781954": { "compartment": "compartment_1660541", "id": "reaction_10781954", "reactome": "R-SCE-6784738", "name": "Degradation of PCSK9:LDLR:Clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781950" ], "products": [ "species_10781948" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "P09232", "YEL060C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C" ] }, "reaction_10785158": { "compartment": "compartment_70101", "id": "reaction_10785158", "reactome": "R-SCE-6813720", "name": "NCEH1 hydrolyzes cholesterol esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163579", "species_29356" ], "products": [ "species_216762", "species_8876730" ], "modifiers": [ [ "species_10785155", "catalyst" ] ], "additional_components": [ "YGR263C" ] }, "reaction_10768163": { "compartment": "compartment_984", "id": "reaction_10768163", "reactome": "R-SCE-264695", "name": "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194276", "species_171149" ], "products": [ "species_194236", "species_171076" ], "modifiers": [ [ "species_10768160", "catalyst" ] ], "additional_components": [ "P47139", "YJR098C", "P54857", "YDR058C" ] }, "reaction_10786892": { "compartment": "compartment_12045", "id": "reaction_10786892", "reactome": "R-SCE-8876485", "name": "CHOL translocates from lysosome membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786890" ], "products": [ "species_193384", "species_10786888" ], "modifiers": [], "additional_components": [ "Q12200", "YPL006W", "species_171095", "YPL006W" ] }, "reaction_10781952": { "compartment": "compartment_1660541", "id": "reaction_10781952", "reactome": "R-SCE-6784729", "name": "PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781918" ], "products": [ "species_10781950" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P09232", "YEL060C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P36000", "YKL135C", "P09232", "YEL060C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C" ] }, "reaction_10785516": { "compartment": "compartment_70101", "id": "reaction_10785516", "reactome": "R-SCE-8850945", "name": "Casein kinase II phosphorylates PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767316", "species_113592" ], "products": [ "species_29370", "species_10785514" ], "modifiers": [ [ "species_10774577", "catalyst" ] ], "additional_components": [ "YNL128W", "YNL128W", "P15790", "CKA1", "P38930", "CKB2", "P19454", "CKA2" ] }, "reaction_10787467": { "compartment": "compartment_70101", "id": "reaction_10787467", "reactome": "R-SCE-8948800", "name": "TNKS and TNKS2 PARylate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767316", "species_29360" ], "products": [ "species_10787457", "species_197277" ], "modifiers": [ [ "species_10787462", "catalyst" ] ], "additional_components": [ "YNL128W", "YNL128W", "YGR232W" ] }, "reaction_10784359": { "compartment": "compartment_70101", "id": "reaction_10784359", "reactome": "R-SCE-6807206", "name": "USP13 and OTUD3 deubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784356", "species_29356" ], "products": [ "species_10767316", "species_10760634" ], "modifiers": [ [ "species_10781697", "catalyst" ] ], "additional_components": [ "YNL128W", "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YBR058C" ] }, "reaction_10784353": { "compartment": "compartment_70101", "id": "reaction_10784353", "reactome": "R-SCE-6807134", "name": "NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767316", "species_10760634" ], "products": [ "species_10784348" ], "modifiers": [ [ "species_10772117", "catalyst" ] ], "additional_components": [ "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YNL128W", "YER125W" ] }, "reaction_10785528": { "compartment": "compartment_70101", "id": "reaction_10785528", "reactome": "R-SCE-8850992", "name": "Proteasome degrades polyubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785526" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P53916", "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10784088": { "compartment": "compartment_876", "id": "reaction_10784088", "reactome": "R-SCE-6801101", "name": "RABGGTA binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784079", "species_10784084" ], "products": [ "species_10784086" ], "modifiers": [], "additional_components": [ "YJL031C", "YPR176C", "P20133", "YPR176C", "Q00618", "YJL031C" ] }, "reaction_10784074": { "compartment": "compartment_70101", "id": "reaction_10784074", "reactome": "R-SCE-6800793", "name": "PIDD1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784068" ], "products": [ "species_10784072" ], "modifiers": [], "additional_components": [ "YJL005W", "YJL005W" ] }, "reaction_10784097": { "compartment": "compartment_70101", "id": "reaction_10784097", "reactome": "R-SCE-6801109", "name": "CHM binds RGGT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784093", "species_10784086" ], "products": [ "species_10784095" ], "modifiers": [], "additional_components": [ "YOR370C", "P20133", "YPR176C", "Q00618", "YJL031C", "P32864", "YOR370C", "P20133", "YPR176C", "Q00618", "YJL031C" ] }, "reaction_10784124": { "compartment": "compartment_17927", "id": "reaction_10784124", "reactome": "R-SCE-6801242", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784120", "species_10784101" ], "products": [ "species_10784122" ], "modifiers": [], "additional_components": [ "P35200", "YLR168C", "Q05776", "YLR193C", "Q04006", "YDR185C", "P35200", "YLR168C", "Q05776", "YLR193C", "Q04006", "YDR185C", "O60200", "MDM35" ] }, "reaction_10784070": { "compartment": "compartment_7660", "id": "reaction_10784070", "reactome": "R-SCE-6800490", "name": "ATM phosphorylates PIDD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10784065" ], "products": [ "species_113582", "species_10784068" ], "modifiers": [ [ "species_10768327", "catalyst" ] ], "additional_components": [ "YJL005W", "YJL005W", "YBL088C" ] }, "reaction_10784127": { "compartment": "compartment_17906", "id": "reaction_10784127", "reactome": "R-SCE-6801250", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590" ], "products": [ "species_1524101" ], "modifiers": [ [ "species_10784122", "catalyst" ] ], "additional_components": [ "P35200", "YLR168C", "Q05776", "YLR193C", "Q04006", "YDR185C", "O60200", "MDM35" ] }, "reaction_10788980": { "compartment": "compartment_70101", "id": "reaction_10788980", "reactome": "R-SCE-9661405", "name": "ABCC1 transports BIL from cytosol to extracellular region (blood)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189386" ], "products": [ "species_9661418" ], "modifiers": [ [ "species_10768249", "catalyst" ] ], "additional_components": [ "YDR135C" ] }, "reaction_10779396": { "compartment": "compartment_7660", "id": "reaction_10779396", "reactome": "R-SCE-5683792", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779391" ], "products": [ "species_113582", "species_10761098" ], "modifiers": [ [ "species_10779391", "catalyst" ] ], "additional_components": [ "P39009", "YDL101C", "YDL101C", "P39009", "YDL101C" ] }, "reaction_10766387": { "compartment": "compartment_7660", "id": "reaction_10766387", "reactome": "R-SCE-176264", "name": "Recruitment of the Rad9-Hus1-Rad1 complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766382", "species_10766378" ], "products": [ "species_10766384" ], "modifiers": [ [ "species_10766382", "catalyst" ] ], "additional_components": [ "P22336", "YAR007C", "P32641", "YER173W", "P40348", "YJR068W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "Q02574", "YLR288C", "Q08949", "YPL194W", "P48581", "YOR368W", "Q02574", "YLR288C", "P22336", "YAR007C", "Q08949", "YPL194W", "P32641", "YER173W", "P40348", "YJR068W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P48581", "YOR368W", "P38629", "YNL290W", "P22336", "YAR007C", "P32641", "YER173W", "P40348", "YJR068W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W" ] }, "reaction_10787270": { "compartment": "compartment_70101", "id": "reaction_10787270", "reactome": "R-SCE-8941895", "name": "Formation of CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787266", "species_10787216" ], "products": [ "species_10787268" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P00546", "YBR160W", "P36005", "YKL161C", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760833": { "compartment": "compartment_7660", "id": "reaction_10760833", "reactome": "R-SCE-68950", "name": "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10760281", "species_30187", "species_29604", "species_29892" ], "products": [ "species_10760830" ], "modifiers": [ [ "species_10760246", "catalyst" ] ], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W" ] }, "reaction_10785898": { "compartment": "compartment_70101", "id": "reaction_10785898", "reactome": "R-SCE-8853496", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785889", "species_10785894" ], "products": [ "species_10785896" ], "modifiers": [], "additional_components": [ "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "YPL209C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C" ] }, "reaction_10763956": { "compartment": "compartment_7660", "id": "reaction_10763956", "reactome": "R-SCE-75809", "name": "Phosphorylation of Cdc25C at Ser216 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763791", "species_29358" ], "products": [ "species_10763794", "species_113582" ], "modifiers": [ [ "species_10761098", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "YDL101C" ] }, "reaction_10774551": { "compartment": "compartment_70101", "id": "reaction_10774551", "reactome": "R-SCE-2529015", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774539", "species_29356" ], "products": [ "species_10774549", "species_29372" ], "modifiers": [ [ "species_2529006", "catalyst" ] ], "additional_components": [ "P38170", "YBL097W", "P38989", "YFR031C", "Q12267", "YLR086W", "Q06156", "YLR272C", "Q06680", "YDR325W", "P38170", "YBL097W", "P38989", "YFR031C", "Q12267", "YLR086W", "Q06156", "YLR272C", "Q06680", "YDR325W" ] }, "reaction_10784202": { "compartment": "compartment_7660", "id": "reaction_10784202", "reactome": "R-SCE-6804724", "name": "MDM2 ubiquitinates phosphorylated MDM4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768310", "species_10760537" ], "products": [ "species_10784199" ], "modifiers": [ [ "species_10768310", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W" ] }, "reaction_10774378": { "compartment": "compartment_1598585", "id": "reaction_10774378", "reactome": "R-SCE-2466068", "name": "Phosphorylation of cohesin by PLK1 at chromosomal arms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10774363" ], "products": [ "species_10774375", "species_29370" ], "modifiers": [ [ "species_10768675", "catalyst" ] ], "additional_components": [ "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "YMR001C" ] }, "reaction_10788671": { "compartment": "compartment_13231", "id": "reaction_10788671", "reactome": "R-SCE-9624798", "name": "LBR binds KPNB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788667", "species_10768074" ], "products": [ "species_10788669" ], "modifiers": [], "additional_components": [ "YNL280C", "YLR347C", "Q06142", "YLR347C", "P32462", "YNL280C" ] }, "reaction_10763796": { "compartment": "compartment_7660", "id": "reaction_10763796", "reactome": "R-SCE-75010", "name": "Phosphorylation of Cdc25C at Ser 216 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763791", "species_29358" ], "products": [ "species_10763794", "species_113582" ], "modifiers": [ [ "species_10761086", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "P36002", "YKL198C", "P47116", "YJR059W", "P06782", "YDR477W" ] }, "reaction_10774466": { "compartment": "compartment_7660", "id": "reaction_10774466", "reactome": "R-SCE-2473152", "name": "Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10774462" ], "products": [ "species_2485002", "species_10774464" ], "modifiers": [ [ "species_10774449", "catalyst" ] ], "additional_components": [ "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "YFR027W" ] }, "reaction_10766462": { "compartment": "compartment_7660", "id": "reaction_10766462", "reactome": "R-SCE-187948", "name": "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10766260" ], "products": [ "species_113582", "species_10766262" ], "modifiers": [ [ "species_10760454", "catalyst" ] ], "additional_components": [ "YGL003C", "YGL003C", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10787375": { "compartment": "compartment_7660", "id": "reaction_10787375", "reactome": "R-SCE-8942836", "name": "CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10787337" ], "products": [ "species_113582", "species_10787373" ], "modifiers": [ [ "species_10763257", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "Q03290", "YDR460W", "P37366", "YPR025C", "P06242", "YDL108W" ] }, "reaction_10788685": { "compartment": "compartment_70101", "id": "reaction_10788685", "reactome": "R-SCE-9624876", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788673", "species_9624879" ], "products": [ "species_10788683" ], "modifiers": [], "additional_components": [ "P32835", "YLR293C", "species_29438", "P32835", "YLR293C", "species_29438" ] }, "reaction_10764018": { "compartment": "compartment_13231", "id": "reaction_10764018", "reactome": "R-SCE-75823", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763979" ], "products": [ "species_10764006" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10766207": { "compartment": "compartment_13231", "id": "reaction_10766207", "reactome": "R-SCE-170159", "name": "Translocation of Cdc25 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766203" ], "products": [ "species_10766205" ], "modifiers": [], "additional_components": [ "P23748", "YMR036C", "P23748", "YMR036C" ] }, "reaction_10788374": { "compartment": "compartment_70101", "id": "reaction_10788374", "reactome": "R-SCE-9029987", "name": "p-S216-CDC25C translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763794" ], "products": [ "species_10763798" ], "modifiers": [], "additional_components": [ "YMR036C", "YMR036C" ] }, "reaction_10760284": { "compartment": "compartment_7660", "id": "reaction_10760284", "reactome": "R-SCE-68913", "name": "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10760279" ], "products": [ "species_10760281", "species_10760275" ], "modifiers": [ [ "species_10760279", "catalyst" ] ], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P20457", "YKL045W" ] }, "reaction_10774945": { "compartment": "compartment_70101", "id": "reaction_10774945", "reactome": "R-SCE-3002798", "name": "Cytosolic PLK1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765349" ], "products": [ "species_10765474" ], "modifiers": [], "additional_components": [ "YMR001C", "YMR001C" ] }, "reaction_10766199": { "compartment": "compartment_13231", "id": "reaction_10766199", "reactome": "R-SCE-170149", "name": "Translocation of active Cdc25C to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765343" ], "products": [ "species_10766197" ], "modifiers": [], "additional_components": [ "YMR036C", "YMR036C" ] }, "reaction_10789351": { "compartment": "compartment_7660", "id": "reaction_10789351", "reactome": "R-SCE-9754129", "name": "CDK6 inhibitors bind CDK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9754132", "species_10787355" ], "products": [ "species_10789349" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=10426", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=7379", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "P24868", "YGR108W", "P00546", "YBR160W", "P36005", "YKL161C", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10426", "P20438", "YPL256C", "P32943", "YGR109C", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "LigandDisplayForward?ligandId=7934" ] }, "reaction_10788688": { "compartment": "compartment_70101", "id": "reaction_10788688", "reactome": "R-SCE-9624893", "name": "RAN stimulates fusion of nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788683", "species_29356" ], "products": [ "species_10767791", "species_29372", "species_9624890" ], "modifiers": [ [ "species_10774940", "catalyst" ] ], "additional_components": [ "P32835", "YLR293C", "species_29438", "species_29420", "P32835", "YLR293C", "P11745", "YMR235C", "Q12306", "YDR510W" ] }, "reaction_10789361": { "compartment": "compartment_7660", "id": "reaction_10789361", "reactome": "R-SCE-9754130", "name": "CDK4 inhibitors bind CDK4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787371", "species_9754127" ], "products": [ "species_10789359" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "LigandDisplayForward?ligandId=7938", "LigandDisplayForward?ligandId=5950", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=10426", "LigandDisplayForward?ligandId=5707", "LigandDisplayForward?ligandId=7744", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "pubchem.compound:9933545", "LigandDisplayForward?ligandId=8203", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=5680", "LigandDisplayForward?ligandId=7938", "P13365", "YAL040C", "LigandDisplayForward?ligandId=11189", "P24868", "YGR108W", "P00546", "YBR160W", "P36005", "YKL161C", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5707", "LigandDisplayForward?ligandId=7383", "P24869", "YPR119W", "pubchem.compound:9933545", "LigandDisplayForward?ligandId=8203", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=5950", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=10426", "P20438", "YPL256C", "P32943", "YGR109C", "LigandDisplayForward?ligandId=7744", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7382", "P30283", "YPR120C", "P20437", "YMR199W", "LigandDisplayForward?ligandId=5680" ] }, "reaction_10774454": { "compartment": "compartment_7660", "id": "reaction_10774454", "reactome": "R-SCE-2468039", "name": "Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774436", "species_113560" ], "products": [ "species_2485002", "species_10774444" ], "modifiers": [ [ "species_10774449", "catalyst" ] ], "additional_components": [ "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "YFR027W" ] }, "reaction_10774580": { "compartment": "compartment_70101", "id": "reaction_10774580", "reactome": "R-SCE-2529020", "name": "CK2 phosphorylates condensin I subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774549", "species_113592" ], "products": [ "species_29370", "species_10774539" ], "modifiers": [ [ "species_10774577", "catalyst" ] ], "additional_components": [ "P38170", "YBL097W", "P38989", "YFR031C", "Q12267", "YLR086W", "Q06156", "YLR272C", "Q06680", "YDR325W", "P38170", "YBL097W", "P38989", "YFR031C", "Q12267", "YLR086W", "Q06156", "YLR272C", "Q06680", "YDR325W", "P15790", "CKA1", "P38930", "CKB2", "P19454", "CKA2" ] }, "reaction_10766243": { "compartment": "compartment_7660", "id": "reaction_10766243", "reactome": "R-SCE-174110", "name": "Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10766239" ], "products": [ "species_10766241", "species_113550" ], "modifiers": [ [ "species_10761051", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "YMR036C" ] }, "reaction_10774394": { "compartment": "compartment_70101", "id": "reaction_10774394", "reactome": "R-SCE-2467775", "name": "Autocleavage of ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774383" ], "products": [ "species_10774391" ], "modifiers": [ [ "species_10774383", "catalyst" ] ], "additional_components": [ "YGR098C", "Q03018", "YGR098C", "YGR098C" ] }, "reaction_10765338": { "compartment": "compartment_70101", "id": "reaction_10765338", "reactome": "R-SCE-141437", "name": "Formation of the MCC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765330", "species_10765320", "species_10765315", "species_10765325" ], "products": [ "species_10765332" ], "modifiers": [], "additional_components": [ "YJL030W", "YOR026W", "P47074", "YJL013C", "P41695", "YGR188C", "YGL116W", "P47074", "YJL013C", "P40958", "YJL030W", "P41695", "YGR188C", "P26309", "YGL116W", "P26449", "YOR026W" ] }, "reaction_10765336": { "compartment": "compartment_70101", "id": "reaction_10765336", "reactome": "R-SCE-141429", "name": "Inactivation of APC/C via CDC20 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765330", "species_10765325" ], "products": [ "species_10765334" ], "modifiers": [], "additional_components": [ "YJL030W", "YGL116W", "P40958", "YJL030W", "P26309", "YGL116W" ] }, "reaction_10774266": { "compartment": "compartment_20699", "id": "reaction_10774266", "reactome": "R-SCE-2214351", "name": "PLK1 phosphorylates GORASP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774258", "species_113592" ], "products": [ "species_10774263", "species_29370" ], "modifiers": [ [ "species_10774258", "catalyst" ] ], "additional_components": [ "P01123", "YFL038C", "P32562", "YMR001C", "species_29438", "Q04410", "YDR517W", "P01123", "YFL038C", "P32562", "YMR001C", "species_29438", "Q04410", "YDR517W", "P01123", "YFL038C", "P32562", "YMR001C", "species_29438", "Q04410", "YDR517W" ] }, "reaction_10784232": { "compartment": "compartment_7660", "id": "reaction_10784232", "reactome": "R-SCE-6804955", "name": "ATM phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10768288" ], "products": [ "species_113582", "species_10784230" ], "modifiers": [ [ "species_10768327", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "YBL088C" ] }, "reaction_10766264": { "compartment": "compartment_13231", "id": "reaction_10766264", "reactome": "R-SCE-174273", "name": "Translocation of Cyclin A:Cdk2 complexes to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766227" ], "products": [ "species_10766241" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10768330": { "compartment": "compartment_7660", "id": "reaction_10768330", "reactome": "R-SCE-349455", "name": "Phosphorylation of MDM4 by ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10768320" ], "products": [ "species_113582", "species_10768298" ], "modifiers": [ [ "species_10768327", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "YBL088C" ] }, "reaction_10777308": { "compartment": "compartment_13231", "id": "reaction_10777308", "reactome": "R-SCE-5221130", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_5221122" ], "products": [ "species_113550", "species_5221124" ], "modifiers": [ [ "species_10776501", "catalyst" ] ], "additional_components": [ "YMR165C" ] }, "reaction_10768312": { "compartment": "compartment_7660", "id": "reaction_10768312", "reactome": "R-SCE-349426", "name": "Phosphorylation of MDM4 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10768298" ], "products": [ "species_113582", "species_10768310" ], "modifiers": [ [ "species_10761098", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "YDL101C" ] }, "reaction_10764016": { "compartment": "compartment_13231", "id": "reaction_10764016", "reactome": "R-SCE-75822", "name": "Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763990" ], "products": [ "species_10764014" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10766229": { "compartment": "compartment_70101", "id": "reaction_10766229", "reactome": "R-SCE-174054", "name": "Formation of Cyclin A:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760999", "species_10766189" ], "products": [ "species_10766227" ], "modifiers": [], "additional_components": [ "YBR160W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10774943": { "compartment": "compartment_13231", "id": "reaction_10774943", "reactome": "R-SCE-3000449", "name": "UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774930", "species_10774813" ], "products": [ "species_10774805", "species_10774940" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P11745", "YMR235C", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "P11745", "YMR235C", "Q12306", "YDR510W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10787339": { "compartment": "compartment_13231", "id": "reaction_10787339", "reactome": "R-SCE-8942803", "name": "Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787303" ], "products": [ "species_10787337" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10788681": { "compartment": "compartment_1598585", "id": "reaction_10788681", "reactome": "R-SCE-9624845", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10767791" ], "products": [ "species_10788673", "species_29420" ], "modifiers": [ [ "species_10788678", "catalyst" ] ], "additional_components": [ "species_29420", "P32835", "YLR293C", "P32835", "YLR293C", "species_29438", "YGL097W" ] }, "reaction_10766195": { "compartment": "compartment_13231", "id": "reaction_10766195", "reactome": "R-SCE-170120", "name": "Translocation of Cdc25B to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766191" ], "products": [ "species_10766193" ], "modifiers": [], "additional_components": [ "YMR036C", "YMR036C" ] }, "reaction_10766465": { "compartment": "compartment_7660", "id": "reaction_10766465", "reactome": "R-SCE-187949", "name": "CAK-mediated phosphorylation of Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766241", "species_29358" ], "products": [ "species_113582", "species_10760454" ], "modifiers": [ [ "species_10763257", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03290", "YDR460W", "P37366", "YPR025C", "P06242", "YDL108W" ] }, "reaction_10779393": { "compartment": "compartment_7660", "id": "reaction_10779393", "reactome": "R-SCE-5683774", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779389" ], "products": [ "species_10779391" ], "modifiers": [], "additional_components": [ "YDL101C", "P39009", "YDL101C" ] }, "reaction_10784210": { "compartment": "compartment_7660", "id": "reaction_10784210", "reactome": "R-SCE-6804741", "name": "MDM2 forms homo- or heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768288", "species_10784204" ], "products": [ "species_10784208" ], "modifiers": [ [ "species_10768327", "inhibitor" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "YBL088C" ] }, "reaction_10785940": { "compartment": "compartment_70101", "id": "reaction_10785940", "reactome": "R-SCE-8854041", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760634", "species_10785896" ], "products": [ "species_10785937" ], "modifiers": [ [ "species_10785896", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C" ] }, "reaction_10764022": { "compartment": "compartment_70101", "id": "reaction_10764022", "reactome": "R-SCE-75825", "name": "Proteasome mediated degradation of Cyclin D1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764020" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P05759", "RPS31", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P30283", "YPR120C", "P20437", "YMR199W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10785942": { "compartment": "compartment_70101", "id": "reaction_10785942", "reactome": "R-SCE-8854044", "name": "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785937" ], "products": [ "species_10785889", "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10772729": { "compartment": "compartment_876", "id": "reaction_10772729", "reactome": "R-SCE-1296348", "name": "Activation of TWIK-related K+ channel (TREK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772726", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10766923": { "compartment": "compartment_70101", "id": "reaction_10766923", "reactome": "R-SCE-195664", "name": "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_29368", "species_195691" ], "products": [ "species_29366", "species_195655", "species_29356" ], "modifiers": [ [ "species_10766920", "catalyst" ] ], "additional_components": [ "YLR056W" ] }, "reaction_10764912": { "compartment": "compartment_12045", "id": "reaction_10764912", "reactome": "R-SCE-111883", "name": "Hydrolysis of phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_140356", "species_428981" ], "modifiers": [ [ "species_10764907", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C", "species_429802" ] }, "reaction_10764967": { "compartment": "compartment_70101", "id": "reaction_10764967", "reactome": "R-SCE-112037", "name": "Inactivation of PLC beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764872", "species_29356" ], "products": [ "species_29372", "species_10764856", "species_10764965" ], "modifiers": [], "additional_components": [ "P32383", "YPL268W", "species_29438", "P10823", "YER020W", "YPL268W", "species_29420", "P10823", "YER020W" ] }, "reaction_10764909": { "compartment": "compartment_70101", "id": "reaction_10764909", "reactome": "R-SCE-111881", "name": "Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_74016", "species_10764905" ], "products": [ "species_10764907" ], "modifiers": [], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C", "species_429802" ] }, "reaction_10764875": { "compartment": "compartment_70101", "id": "reaction_10764875", "reactome": "R-SCE-111879", "name": "PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10764872", "catalyst" ] ], "additional_components": [ "P32383", "YPL268W", "species_29438", "P10823", "YER020W" ] }, "reaction_10764925": { "compartment": "compartment_70101", "id": "reaction_10764925", "reactome": "R-SCE-111898", "name": "Phosphorylation of cPLA2 by ERK-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10764922" ], "products": [ "species_29370", "species_10764905" ], "modifiers": [ [ "species_10764614", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "YBL016W" ] }, "reaction_10779083": { "compartment": "compartment_70101", "id": "reaction_10779083", "reactome": "R-SCE-5679041", "name": "ABCC2 transports BMG,BDG from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_5679042", "species_29356" ], "products": [ "species_29370", "species_5679034", "species_29372" ], "modifiers": [ [ "species_10772886", "catalyst" ] ], "additional_components": [ "species_159160", "species_159149", "species_159160", "species_159149", "P14772", "YLL015W", "P39109", "YDR135C", "P32386", "YLL048C", "P38735", "YHL035C" ] }, "reaction_10774756": { "compartment": "compartment_7660", "id": "reaction_10774756", "reactome": "R-SCE-2990833", "name": "Conjugation of SUMO1 to UBA2:SAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10774743", "species_10774738" ], "products": [ "species_10774753", "species_164121", "species_113541" ], "modifiers": [ [ "species_10774738", "catalyst" ] ], "additional_components": [ "YDR510W", "P52488", "YDR390C", "Q06624", "YPR180W", "P52488", "YDR390C", "Q06624", "YPR180W", "Q12306", "YDR510W", "P52488", "YDR390C", "Q06624", "YPR180W" ] }, "reaction_10774681": { "compartment": "compartment_70101", "id": "reaction_10774681", "reactome": "R-SCE-2730835", "name": "Autophosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767671", "species_113592" ], "products": [ "species_29370", "species_10774679" ], "modifiers": [], "additional_components": [ "species_112275", "P24583", "YBL105C", "species_112275", "P24583", "YBL105C" ] }, "reaction_10766028": { "compartment": "compartment_70101", "id": "reaction_10766028", "reactome": "R-SCE-168162", "name": "Phosphorylation of human JNKs by activated MKK4/MKK7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10765968" ], "products": [ "species_29370", "species_10765974" ], "modifiers": [ [ "species_10766025", "catalyst" ] ], "additional_components": [ "YPR054W", "YPR054W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10770904": { "compartment": "compartment_70101", "id": "reaction_10770904", "reactome": "R-SCE-451418", "name": "Pellino ubiquitinates IRAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770887" ], "products": [ "species_10770901" ], "modifiers": [ [ "species_10770887", "catalyst" ] ], "additional_components": [ "P43633", "YGL021W", "P32789", "YBL009W", "P05759", "RPS31", "P53152", "MMS2", "P52490", "UBC13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P43633", "YGL021W", "P32789", "YBL009W", "P53152", "MMS2", "P52490", "UBC13", "P43633", "YGL021W", "P32789", "YBL009W", "P05759", "RPS31", "P53152", "MMS2", "P52490", "UBC13", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10789090": { "compartment": "compartment_70101", "id": "reaction_10789090", "reactome": "R-SCE-9690461", "name": "FKBP1A binds tacrolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678991", "species_10789071" ], "products": [ "species_10789088" ], "modifiers": [], "additional_components": [ "YNL135C", "P20081", "YNL135C", "species_9678991" ] }, "reaction_10769144": { "compartment": "compartment_70101", "id": "reaction_10769144", "reactome": "R-SCE-392530", "name": "p-S400-Cot phosphorylates NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769138", "species_113592" ], "products": [ "species_29370", "species_10769141" ], "modifiers": [ [ "species_10768963", "catalyst" ] ], "additional_components": [ "YCR073C", "YCR073C", "P25390", "YCR073C", "P53599", "YNR031C" ] }, "reaction_10767769": { "compartment": "compartment_7660", "id": "reaction_10767769", "reactome": "R-SCE-203797", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10767354" ], "products": [ "species_10767374", "species_113550" ], "modifiers": [ [ "species_10767766", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "P41808", "YPR054W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P41808", "YPR054W", "Q00772", "YHR030C", "P14681", "YGR040W", "P40479", "YIL113W", "P38590", "YNL053W" ] }, "reaction_10772408": { "compartment": "compartment_70101", "id": "reaction_10772408", "reactome": "R-SCE-983156", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772358", "species_113592", "species_10772364" ], "products": [ "species_10772379", "species_111294", "species_10772356", "species_76577" ], "modifiers": [ [ "species_10772364", "catalyst" ] ], "additional_components": [ "P22515", "YKL210W", "P15732", "YDR059C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P05759", "RPS31", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52491", "YLR306W", "P21734", "YDR177W", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P32943", "YGR109C", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P22515", "YKL210W", "P15732", "YDR059C", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P52491", "YLR306W", "P21734", "YDR177W", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P32943", "YGR109C", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C" ] }, "reaction_10783476": { "compartment": "compartment_1462052", "id": "reaction_10783476", "reactome": "R-SCE-6798748", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783290" ], "products": [ "species_10783474" ], "modifiers": [], "additional_components": [ "Q06625", "YPR184W", "P32807", "YMR284W", "P25043", "YOR157C", "P06738", "YPR160W", "P02994", "YBR118W", "P47103", "YJR032W", "P04806", "YFR053C", "Q12096", "YOR320C", "Q04437", "YMR106C", "Q03262", "YMR278W", "P38764", "YHR027C", "P17121", "YDR389W", "Q04120", "YDR453C", "P52489", "YOR347C", "Q08723", "YOR261C", "P38930", "CKB2", "P12709", "YBR196C", "P36010", "YKL067W", "P34760", "YML028W", "P32485", "YLR113W", "P32379", "YGR253C", "P38696", "YHR129C", "P16862", "YMR205C", "P40361", "YJL070C", "P25694", "YDL126C", "P15202", "YDR256C", "P46958", "YJL146W", "P47011", "YJL137C", "Q06103", "YPR108W", "P21954", "YDL066W", "P16861", "YGR240C", "P17709", "YCL040W", "P23724", "YBL041W", "P50094", "YML056C", "P15274", "YML035C", "P33297", "YOR117W", "Q06204", "YLR446W", "Q03280", "YDR457W", "P38985", "YDL092W", "Q12377", "YDL097C", "P10592", "YLL024C", "P47079", "YJL008C", "P32873", "YPL115C", "P11633", "YBR089C-A", "P39960", "YER155C", "P32769", "YKR084C", "Q06549", "YLR245C", "P15891", "YCR088W", "Q12250", "YDL147W", "P04807", "YGL253W", "P00549", "YAL038W", "P50095", "YLR432W", "Q08491", "SKI7", "P23639", "YML092C", "Q12156", "YDR063W", "P39083", "YOR127W", "P53691", "YLR216C", "P32324", "EFT2", "P38697", "YHR216W", "P49435", "YML022W", "P02829", "YPL240C", "P38339", "YBR260C", "P39958", "YER136W", "P05373", "YGL040C", "Q05788", "YLR209C", "P06634", "YOR204W", "P38862", "YHR171W", "P40518", "YIL062C", "Q04409", "YDR516C", "P38150", "YJL070C", "Q06407", "YDR379W", "Q04062", "YDR427W", "P33299", "YKL145W", "P32464", "YKL189W", "P40016", "YER021W", "P15108", "YMR186W", "P39988", "YEL029C", "P43588", "YFR004W", "P36143", "YKR058W", "Q06625", "YPR184W", "P32807", "YMR284W", "P25043", "YOR157C", "P06738", "YPR160W", "P02994", "YBR118W", "P47103", "YJR032W", "P04806", "YFR053C", "Q12096", "YOR320C", "Q04437", "YMR106C", "Q03262", "YMR278W", "P38764", "YHR027C", "P17121", "YDR389W", "Q04120", "YDR453C", "P52489", "YOR347C", "Q08723", "YOR261C", "P38930", "CKB2", "P12709", "YBR196C", "P36010", "YKL067W", "P34760", "YML028W", "P32485", "YLR113W", "P32379", "YGR253C", "P38696", "YHR129C", "P16862", "YMR205C", "P40361", "YJL070C", "P25694", "YDL126C", "P15202", "YDR256C", "P46958", "YJL146W", "P47011", "YJL137C", "Q06103", "YPR108W", "P21954", "YDL066W", "P16861", "YGR240C", "P17709", "YCL040W", "P23724", "YBL041W", "P50094", "YML056C", "P15274", "YML035C", "P33297", "YOR117W", "Q06204", "YLR446W", "Q03280", "YDR457W", "P38985", "YDL092W", "Q12377", "YDL097C", "P10592", "YLL024C", "P47079", "YJL008C", "P32873", "YPL115C", "P11633", "YBR089C-A", "P39960", "YER155C", "P32769", "YKR084C", "Q06549", "YLR245C", "P15891", "YCR088W", "Q12250", "YDL147W", "P04807", "YGL253W", "P00549", "YAL038W", "P50095", "YLR432W", "Q08491", "SKI7", "P23639", "YML092C", "Q12156", "YDR063W", "P39083", "YOR127W", "P53691", "YLR216C", "P32324", "EFT2", "P38697", "YHR216W", "P49435", "YML022W", "P02829", "YPL240C", "P38339", "YBR260C", "P39958", "YER136W", "P05373", "YGL040C", "Q05788", "YLR209C", "P06634", "YOR204W", "P38862", "YHR171W", "P40518", "YIL062C", "Q04409", "YDR516C", "P38150", "YJL070C", "Q06407", "YDR379W", "Q04062", "YDR427W", "P33299", "YKL145W", "P32464", "YKL189W", "P40016", "YER021W", "P15108", "YMR186W", "P39988", "YEL029C", "P43588", "YFR004W", "P36143", "YKR058W" ] }, "reaction_10774052": { "compartment": "compartment_876", "id": "reaction_10774052", "reactome": "R-SCE-2029471", "name": "Hydrolysis of PC to PA by PLD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_29356" ], "products": [ "species_264618", "species_1602448" ], "modifiers": [ [ "species_10774047", "catalyst" ] ], "additional_components": [ "YKR031C" ] }, "reaction_10772367": { "compartment": "compartment_70101", "id": "reaction_10772367", "reactome": "R-SCE-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10772360" ], "products": [ "species_111294", "species_10772356", "species_10772364", "species_76577" ], "modifiers": [ [ "species_10772267", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "Q08273", "YOL133W", "P22515", "YKL210W", "P15732", "YDR059C", "P38042", "YBL084C", "P52490", "UBC13", "Q04601", "YDR118W", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P52492", "YOR339C", "P06104", "YGL058W", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P53197", "YGL003C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "P52286", "YDR328C", "P28263", "YEL012W", "P54860", "YDL190C", "P26309", "YGL116W", "P33296", "YER100W", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P53152", "MMS2", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P20437", "YMR199W", "P21734", "YDR177W", "P53886", "YNL172W", "P39940", "YER125W", "Q12018", "YDL132W", "P24868", "YGR108W", "Q02159", "YMR022W", "Q05164", "YOL155C", "P15731", "YBR082C", "P24869", "YPR119W", "P25382", "YCR072C", "P52491", "YLR306W", "P19812", "YGR184C", "Q08683", "YOR249C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P32943", "YGR109C", "P14682", "YDR054C", "P30283", "YPR120C", "P16522", "YHR166C", "Q12347", "YLR097C", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P22515", "YKL210W", "P15732", "YDR059C", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P52491", "YLR306W", "P21734", "YDR177W", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P32943", "YGR109C", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C" ] }, "reaction_10783866": { "compartment": "compartment_6800424", "id": "reaction_10783866", "reactome": "R-SCE-6800426", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783854" ], "products": [ "species_10783864" ], "modifiers": [], "additional_components": [ "P38142", "YBR241C", "P37296", "YMR054W", "P32563", "YOR270C", "P38065", "YBL037W", "Q02647", "YDR424C", "P06780", "YPR165W", "P25353", "YCR026C", "P25515", "YEL027W", "P41810", "YDR238C", "P38142", "YBR241C", "P37296", "YMR054W", "P32563", "YOR270C", "P38065", "YBL037W", "Q02647", "YDR424C", "P06780", "YPR165W", "P25353", "YCR026C", "P25515", "YEL027W", "P41810", "YDR238C" ] }, "reaction_10772633": { "compartment": "compartment_1222693", "id": "reaction_10772633", "reactome": "R-SCE-1222516", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10772630", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "P23968", "YHR026W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10769326": { "compartment": "compartment_70101", "id": "reaction_10769326", "reactome": "R-SCE-418436", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29468", "species_29368" ], "products": [ "species_29366", "species_202124", "species_29968" ], "modifiers": [ [ "species_10769321", "catalyst" ] ], "additional_components": [ "YHR042W" ] }, "reaction_10767230": { "compartment": "compartment_7660", "id": "reaction_10767230", "reactome": "R-SCE-198669", "name": "p38MAPK phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767221", "species_29358" ], "products": [ "species_113582", "species_10767227" ], "modifiers": [ [ "species_10765922", "catalyst" ] ], "additional_components": [ "YBR028C", "YBR028C", "YLR113W" ] }, "reaction_10787198": { "compartment": "compartment_70101", "id": "reaction_10787198", "reactome": "R-SCE-8940641", "name": "THOP1 cleaves oligopeptide fragment (8-16aa)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983032" ], "products": [ "species_8955634" ], "modifiers": [ [ "species_10787195", "catalyst" ] ], "additional_components": [ "YCL057W" ] }, "reaction_10772582": { "compartment": "compartment_70101", "id": "reaction_10772582", "reactome": "R-SCE-1168373", "name": "PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_10765242", "species_33625", "species_114519" ], "products": [ "species_10765252" ], "modifiers": [], "additional_components": [ "YBL105C", "species_33625", "P24583", "YBL105C", "species_74016", "species_6797635" ] }, "reaction_10775012": { "compartment": "compartment_70101", "id": "reaction_10775012", "reactome": "R-SCE-3204303", "name": "MRE11 binds cytosolic DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_874088", "species_10775008" ], "products": [ "species_10775010" ], "modifiers": [], "additional_components": [ "P32829", "MRE11", "species_874088" ] }, "reaction_10783010": { "compartment": "compartment_6800173", "id": "reaction_10783010", "reactome": "R-SCE-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782978" ], "products": [ "species_10783008" ], "modifiers": [], "additional_components": [ "P49954", "YLR351C", "P36110", "YKR013W", "Q06549", "YLR245C", "P47033", "YJL078C", "P41912", "YOL110W", "P15891", "YCR088W", "P21954", "YDL066W", "Q10740", "YNL045W", "P43599", "YFR018C", "P07267", "YPL154C", "P40547", "YIL017C", "P33401", "YKL127W", "P47032", "YJL079C", "P49954", "YLR351C", "P36110", "YKR013W", "Q06549", "YLR245C", "P47033", "YJL078C", "P41912", "YOL110W", "P15891", "YCR088W", "P21954", "YDL066W", "Q10740", "YNL045W", "P43599", "YFR018C", "P07267", "YPL154C", "P40547", "YIL017C", "P33401", "YKL127W", "P47032", "YJL079C" ] }, "reaction_10770716": { "compartment": "compartment_7660", "id": "reaction_10770716", "reactome": "R-SCE-450333", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10770713" ], "products": [ "species_113582", "species_10770632" ], "modifiers": [ [ "species_10770705", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10774045": { "compartment": "compartment_876", "id": "reaction_10774045", "reactome": "R-SCE-2029468", "name": "Conversion of PA into DAG by PAP-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_29356" ], "products": [ "species_29372", "species_112275" ], "modifiers": [ [ "species_10774042", "catalyst" ] ], "additional_components": [ "Q05521", "YDR284C", "Q04396", "YDR503C" ] }, "reaction_10783692": { "compartment": "compartment_1470028", "id": "reaction_10783692", "reactome": "R-SCE-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783636" ], "products": [ "species_10783690" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "P17555", "YNL138W", "P06738", "YPR160W", "P40358", "YJL073W", "P39076", "YIL142W", "P02557", "YFL037W", "P36022", "YKR054C", "P32565", "YIL075C", "P17121", "YDR389W", "Q03630", "YML077W", "P50095", "YLR432W", "P53094", "YGL197W", "Q03862", "YDR101C", "P32381", "YDL029W", "Q04228", "YML013W", "P25694", "YDL126C", "P00812", "YPL111W", "P38697", "YHR216W", "P39958", "YER136W", "Q12229", "YDL091C", "Q08412", "YOR042W", "P50094", "YML056C", "P38626", "YIL043C", "P32634", "YER132C", "P40557", "YIL005W", "P24583", "YBL105C", "P47079", "YJL008C", "Q02933", "YPL123C", "P34227", "YBL064C", "P40568", "YIR010W", "P53843", "YNL265C", "P16892", "YBL016W", "P17555", "YNL138W", "P06738", "YPR160W", "P40358", "YJL073W", "P39076", "YIL142W", "P02557", "YFL037W", "P36022", "YKR054C", "P32565", "YIL075C", "P17121", "YDR389W", "Q03630", "YML077W", "P50095", "YLR432W", "P53094", "YGL197W", "Q03862", "YDR101C", "P32381", "YDL029W", "Q04228", "YML013W", "P25694", "YDL126C", "P00812", "YPL111W", "P38697", "YHR216W", "P39958", "YER136W", "Q12229", "YDL091C", "Q08412", "YOR042W", "P50094", "YML056C", "P38626", "YIL043C", "P32634", "YER132C", "P40557", "YIL005W", "P24583", "YBL105C", "P47079", "YJL008C", "Q02933", "YPL123C", "P34227", "YBL064C", "P40568", "YIR010W", "P53843", "YNL265C" ] }, "reaction_10783061": { "compartment": "compartment_6799713", "id": "reaction_10783061", "reactome": "R-SCE-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783055" ], "products": [ "species_10783059" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "P32660", "YER166W", "P38142", "YBR241C", "P39524", "YAL026C", "Q12675", "YDR093W", "P33328", "YOR327C", "Q02647", "YDR424C", "Q04359", "YMR017W", "P36126", "YKR031C", "P25515", "YEL027W", "P31109", "YAL030W", "Q12674", "YMR162C", "P41810", "YDR238C", "P40357", "YGR009C", "P38142", "YBR241C", "P33328", "YOR327C", "Q04359", "YMR017W", "P25515", "YEL027W", "P31109", "YAL030W", "P41810", "YDR238C", "P32660", "YER166W", "P39524", "YAL026C", "Q12675", "YDR093W", "Q02647", "YDR424C", "P36126", "YKR031C", "Q12674", "YMR162C" ] }, "reaction_10766032": { "compartment": "compartment_7660", "id": "reaction_10766032", "reactome": "R-SCE-168440", "name": "Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765963", "species_10765915" ], "products": [ "species_10766030" ], "modifiers": [], "additional_components": [ "YEL009C", "P39970", "YER045C", "P40535", "YIL036W", "Q02100", "YNL167C", "P39970", "YER045C", "P40535", "YIL036W", "P03069", "YEL009C", "Q02100", "YNL167C" ] }, "reaction_10772715": { "compartment": "compartment_70101", "id": "reaction_10772715", "reactome": "R-SCE-1247960", "name": "Activation of p38 MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10772704" ], "products": [ "species_29370", "species_10772712" ], "modifiers": [ [ "species_10770681", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P32485", "YLR113W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10783523": { "compartment": "compartment_6799371", "id": "reaction_10783523", "reactome": "R-SCE-6798749", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783509" ], "products": [ "species_10783521" ], "modifiers": [], "additional_components": [ "P00812", "YPL111W", "P49954", "YLR351C", "P36110", "YKR013W", "P47033", "YJL078C", "Q06142", "YLR347C", "Q06409", "YLR422W", "P43599", "YFR018C", "P07267", "YPL154C", "P40547", "YIL017C", "P27796", "YIL160C", "Q08412", "YOR042W", "P39988", "YEL029C", "P47032", "YJL079C", "P00812", "YPL111W", "P49954", "YLR351C", "P36110", "YKR013W", "P47033", "YJL078C", "Q06142", "YLR347C", "Q06409", "YLR422W", "P43599", "YFR018C", "P07267", "YPL154C", "P40547", "YIL017C", "P27796", "YIL160C", "Q08412", "YOR042W", "P39988", "YEL029C", "P47032", "YJL079C" ] }, "reaction_10770641": { "compartment": "compartment_7660", "id": "reaction_10770641", "reactome": "R-SCE-450222", "name": "Active p38 MAPK phosphorylates MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10770632" ], "products": [ "species_113582", "species_10770638" ], "modifiers": [ [ "species_10770632", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W" ] }, "reaction_10783779": { "compartment": "compartment_6799351", "id": "reaction_10783779", "reactome": "R-SCE-6799350", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783765" ], "products": [ "species_10783777" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "Q06144", "YLR350W", "P38142", "YBR241C", "P53142", "YGL104C", "P33328", "YOR327C", "P32901", "YKR093W", "Q00776", "YPL259C", "Q04359", "YMR017W", "P53224", "YGR038W", "P31109", "YAL030W", "P13856", "YGR152C", "P33333", "YDL052C", "P32660", "YER166W", "P39524", "YAL026C", "Q12675", "YDR093W", "Q04458", "YMR110C", "P36126", "YKR031C", "P32610", "YEL051W", "P25656", "YCR094W", "Q12674", "YMR162C", "Q12091", "YPL170W", "P40357", "YGR009C", "Q06144", "YLR350W", "P38142", "YBR241C", "P53142", "YGL104C", "P33328", "YOR327C", "P32901", "YKR093W", "Q00776", "YPL259C", "Q04359", "YMR017W", "P53224", "YGR038W", "P31109", "YAL030W", "P13856", "YGR152C", "P33333", "YDL052C", "P32660", "YER166W", "P39524", "YAL026C", "Q12675", "YDR093W", "Q04458", "YMR110C", "P36126", "YKR031C", "P32610", "YEL051W", "P25656", "YCR094W", "Q12674", "YMR162C", "Q12091", "YPL170W" ] }, "reaction_10771236": { "compartment": "compartment_70101", "id": "reaction_10771236", "reactome": "R-SCE-874087", "name": "SGT1 binds HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771232", "species_10771226" ], "products": [ "species_10771234" ], "modifiers": [], "additional_components": [ "P02829", "YPL240C", "P15108", "YMR186W", "YOR057W", "P02829", "YPL240C", "Q08446", "YOR057W", "P15108", "YMR186W" ] }, "reaction_10772405": { "compartment": "compartment_70101", "id": "reaction_10772405", "reactome": "R-SCE-983153", "name": "E1 mediated ubiquitin activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10760634", "species_10772397", "species_29926" ], "products": [ "species_111294", "species_76577", "species_10772399", "species_29926" ], "modifiers": [ [ "species_10772397", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "Q99344", "YPR066W", "P38862", "YHR171W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q99344", "YPR066W", "P38862", "YHR171W", "P22515", "YKL210W", "Q99344", "YPR066W", "P38862", "YHR171W" ] }, "reaction_10770762": { "compartment": "compartment_70101", "id": "reaction_10770762", "reactome": "R-SCE-450348", "name": "Activated human JNKs migrate to nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765974" ], "products": [ "species_10765931" ], "modifiers": [], "additional_components": [ "YPR054W", "YPR054W" ] }, "reaction_10782924": { "compartment": "compartment_876", "id": "reaction_10782924", "reactome": "R-SCE-6798743", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782878" ], "products": [ "species_10782922" ], "modifiers": [], "additional_components": [ "P40462", "YIL137C", "Q06144", "YLR350W", "P32454", "YKL157W", "Q00246", "YKR055W", "P06781", "YNL090W", "P38142", "YBR241C", "Q99260", "YLR262C", "P32563", "YOR270C", "P38065", "YBL037W", "P53224", "YGR038W", "P41810", "YDR238C", "P36017", "YOR089C", "P07560", "YFL005W", "Q00245", "YIL118W", "Q12280", "YPL242C", "P06780", "YPR165W", "P32939", "YML001W", "Q04458", "YMR110C", "P37898", "YHR047C", "P48559", "YNL304W", "P40462", "YIL137C", "Q06144", "YLR350W", "P32454", "YKL157W", "Q00246", "YKR055W", "P06781", "YNL090W", "P38142", "YBR241C", "Q99260", "YLR262C", "P32563", "YOR270C", "P38065", "YBL037W", "P53224", "YGR038W", "P41810", "YDR238C", "P36017", "YOR089C", "P07560", "YFL005W", "Q00245", "YIL118W", "Q12280", "YPL242C", "P06780", "YPR165W", "P32939", "YML001W", "Q04458", "YMR110C", "P37898", "YHR047C", "P48559", "YNL304W" ] }, "reaction_10772402": { "compartment": "compartment_70101", "id": "reaction_10772402", "reactome": "R-SCE-983152", "name": "Transfer of ubiquitin from E1 to E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772356", "species_10772399" ], "products": [ "species_10772358", "species_10772397" ], "modifiers": [ [ "species_10772356", "catalyst" ] ], "additional_components": [ "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P22515", "YKL210W", "P15732", "YDR059C", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P52491", "YLR306W", "P21734", "YDR177W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q99344", "YPR066W", "P38862", "YHR171W", "P22515", "YKL210W", "P15732", "YDR059C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P05759", "RPS31", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52491", "YLR306W", "P21734", "YDR177W", "P22515", "YKL210W", "Q99344", "YPR066W", "P38862", "YHR171W", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P22515", "YKL210W", "P15732", "YDR059C", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P52491", "YLR306W", "P21734", "YDR177W" ] }, "reaction_10774030": { "compartment": "compartment_70101", "id": "reaction_10774030", "reactome": "R-SCE-2029454", "name": "Autophosphorylation of PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774023", "species_113592" ], "products": [ "species_29370", "species_10774027", "species_10768894" ], "modifiers": [ [ "species_10768970", "catalyst" ] ], "additional_components": [ "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C", "YHL007C", "species_29438", "P19073", "YLR229C", "YHL007C" ] }, "reaction_10774276": { "compartment": "compartment_70101", "id": "reaction_10774276", "reactome": "R-SCE-2317332", "name": "PIP3 recruits AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10769080" ], "products": [ "species_10767182" ], "modifiers": [], "additional_components": [ "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "P11792", "YHR205W" ] }, "reaction_10772383": { "compartment": "compartment_70101", "id": "reaction_10772383", "reactome": "R-SCE-983150", "name": "Proteasomal cleavage of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983123" ], "products": [ "species_983032", "species_983036", "species_10760634", "species_8942986" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10784185": { "compartment": "compartment_984", "id": "reaction_10784185", "reactome": "R-SCE-6804100", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784177", "species_166005" ], "products": [ "species_10784183" ], "modifiers": [], "additional_components": [ "YBR089C-A", "species_166005", "P11633", "YBR089C-A" ] }, "reaction_10774162": { "compartment": "compartment_161320", "id": "reaction_10774162", "reactome": "R-SCE-2130706", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2213225" ], "products": [ "species_2213226" ], "modifiers": [ [ "species_10774157", "catalyst" ] ], "additional_components": [ "YPL154C" ] }, "reaction_10784181": { "compartment": "compartment_984", "id": "reaction_10784181", "reactome": "R-SCE-6804099", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784177", "species_181015" ], "products": [ "species_10784179" ], "modifiers": [], "additional_components": [ "YBR089C-A", "P11633", "YBR089C-A", "species_181015" ] }, "reaction_10770513": { "compartment": "compartment_70101", "id": "reaction_10770513", "reactome": "R-SCE-446877", "name": "TRAF6 is K63 poly-ubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770504" ], "products": [ "species_10770510" ], "modifiers": [ [ "species_10770504", "catalyst" ] ], "additional_components": [ "P43633", "YGL021W", "P32789", "YBL009W", "P05759", "RPS31", "P53152", "MMS2", "P52490", "UBC13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P43633", "YGL021W", "P32789", "YBL009W", "P53152", "MMS2", "P52490", "UBC13", "P43633", "YGL021W", "P32789", "YBL009W", "P05759", "RPS31", "P53152", "MMS2", "P52490", "UBC13", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10787872": { "compartment": "compartment_984", "id": "reaction_10787872", "reactome": "R-SCE-9008043", "name": "MAPK8 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10765968" ], "products": [ "species_29370", "species_10765974" ], "modifiers": [], "additional_components": [ "YPR054W", "YPR054W" ] }, "reaction_10772410": { "compartment": "compartment_70101", "id": "reaction_10772410", "reactome": "R-SCE-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772358", "species_10772267", "species_983035" ], "products": [ "species_10772360" ], "modifiers": [], "additional_components": [ "P22515", "YKL210W", "P15732", "YDR059C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P05759", "RPS31", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52491", "YLR306W", "P21734", "YDR177W", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P13365", "YAL040C", "Q08273", "YOL133W", "P22515", "YKL210W", "P15732", "YDR059C", "P38042", "YBL084C", "P52490", "UBC13", "Q04601", "YDR118W", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P52492", "YOR339C", "P06104", "YGL058W", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P53197", "YGL003C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "P52286", "YDR328C", "P28263", "YEL012W", "P54860", "YDL190C", "P26309", "YGL116W", "P33296", "YER100W", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P53152", "MMS2", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P20437", "YMR199W", "P21734", "YDR177W", "P53886", "YNL172W", "P39940", "YER125W", "Q12018", "YDL132W", "P24868", "YGR108W", "Q02159", "YMR022W", "Q05164", "YOL155C", "P15731", "YBR082C", "P24869", "YPR119W", "P25382", "YCR072C", "P52491", "YLR306W", "P19812", "YGR184C", "Q08683", "YOR249C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P32943", "YGR109C", "P14682", "YDR054C", "P30283", "YPR120C", "P16522", "YHR166C", "Q12347", "YLR097C" ] }, "reaction_10772644": { "compartment": "compartment_70101", "id": "reaction_10772644", "reactome": "R-SCE-1236970", "name": "Proteasomal clevage of exogenous antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236719" ], "products": [ "species_983036", "species_8942986" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10765954": { "compartment": "compartment_7660", "id": "reaction_10765954", "reactome": "R-SCE-168053", "name": "Phosphorylated MAPKs phosphorylate ATF-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10765901" ], "products": [ "species_113582", "species_10765915" ], "modifiers": [ [ "species_10765951", "catalyst" ] ], "additional_components": [ "P39970", "YER045C", "P40535", "YIL036W", "Q02100", "YNL167C", "P39970", "YER045C", "P40535", "YIL036W", "Q02100", "YNL167C", "P16892", "YBL016W", "P41808", "YPR054W", "Q00772", "YHR030C", "P32485", "YLR113W", "P14681", "YGR040W" ] }, "reaction_10784297": { "compartment": "compartment_984", "id": "reaction_10784297", "reactome": "R-SCE-6805981", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768264" ], "products": [ "species_10784177" ], "modifiers": [], "additional_components": [ "YBR089C-A", "YBR089C-A" ] }, "reaction_10769000": { "compartment": "compartment_70101", "id": "reaction_10769000", "reactome": "R-SCE-389788", "name": "Activation of PAKs by RAC1 and CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768994", "species_10768894" ], "products": [ "species_10768996", "species_10768998" ], "modifiers": [], "additional_components": [ "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "P48562", "YNL298W", "Q03497", "YHL007C", "species_29438", "Q12469", "YOL113W", "P19073", "YLR229C" ] }, "reaction_10770707": { "compartment": "compartment_70101", "id": "reaction_10770707", "reactome": "R-SCE-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770683" ], "products": [ "species_10770705" ], "modifiers": [], "additional_components": [ "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10772381": { "compartment": "compartment_70101", "id": "reaction_10772381", "reactome": "R-SCE-983147", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772379" ], "products": [ "species_10772267", "species_983123" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C" ] }, "reaction_10767125": { "compartment": "compartment_876", "id": "reaction_10767125", "reactome": "R-SCE-198314", "name": "DAG stimulates protein kinase C-delta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767110", "species_113592" ], "products": [ "species_29370", "species_10767117" ], "modifiers": [ [ "species_10767110", "catalyst" ], [ "species_112275", "catalyst" ] ], "additional_components": [ "YBL105C", "YBL105C", "YBL105C" ] }, "reaction_10782803": { "compartment": "compartment_6798757", "id": "reaction_10782803", "reactome": "R-SCE-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782785" ], "products": [ "species_10782801" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "P33767", "YEL002C", "P33328", "YOR327C", "Q03723", "YML019W", "P25515", "YEL027W", "P31109", "YAL030W", "P13856", "YGR152C", "P07560", "YFL005W", "P53337", "YGR284C", "P39524", "YAL026C", "P48439", "YOR085W", "P40075", "YER120W", "P25656", "YCR094W", "Q12674", "YMR162C", "P40357", "YGR009C", "P33767", "YEL002C", "P33328", "YOR327C", "Q03723", "YML019W", "P25515", "YEL027W", "P31109", "YAL030W", "P13856", "YGR152C", "P07560", "YFL005W", "P53337", "YGR284C", "P39524", "YAL026C", "P48439", "YOR085W", "P40075", "YER120W", "P25656", "YCR094W", "Q12674", "YMR162C" ] }, "reaction_10784060": { "compartment": "compartment_984", "id": "reaction_10784060", "reactome": "R-SCE-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784052" ], "products": [ "species_10784058" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "Q06625", "YPR184W", "P32807", "YMR284W", "P25043", "YOR157C", "P06738", "YPR160W", "P02994", "YBR118W", "P47103", "YJR032W", "Q03957", "YKL139W", "P04806", "YFR053C", "Q12096", "YOR320C", "Q03262", "YMR278W", "P38764", "YHR027C", "Q04120", "YDR453C", "P52489", "YOR347C", "Q08723", "YOR261C", "P38930", "CKB2", "P12709", "YBR196C", "P36010", "YKL067W", "P34760", "YML028W", "P32485", "YLR113W", "P32381", "YDL029W", "P32379", "YGR253C", "P38696", "YHR129C", "P16862", "YMR205C", "P40361", "YJL070C", "P25694", "YDL126C", "P15202", "YDR256C", "P46958", "YJL146W", "P47011", "YJL137C", "Q06142", "YLR347C", "Q06103", "YPR108W", "P21954", "YDL066W", "P16861", "YGR240C", "P17709", "YCL040W", "P23724", "YBL041W", "P33401", "YKL127W", "P50094", "YML056C", "P15274", "YML035C", "P33297", "YOR117W", "Q06204", "YLR446W", "Q10740", "YNL045W", "Q03280", "YDR457W", "P38985", "YDL092W", "Q12377", "YDL097C", "P10592", "YLL024C", "P47079", "YJL008C", "P11633", "YBR089C-A", "P16892", "YBL016W", "P32769", "YKR084C", "Q06549", "YLR245C", "P15891", "YCR088W", "Q12250", "YDL147W", "P04807", "YGL253W", "P00549", "YAL038W", "P50095", "YLR432W", "Q08491", "SKI7", "P23639", "YML092C", "Q12156", "YDR063W", "P53691", "YLR216C", "P32324", "EFT2", "P38697", "YHR216W", "P02829", "YPL240C", "P05373", "YGL040C", "Q05788", "YLR209C", "P06634", "YOR204W", "P38862", "YHR171W", "P40518", "YIL062C", "Q04409", "YDR516C", "P38150", "YJL070C", "Q04062", "YDR427W", "P33299", "YKL145W", "P32464", "YKL189W", "P43599", "YFR018C", "P07267", "YPL154C", "P40016", "YER021W", "P15108", "YMR186W", "P43588", "YFR004W", "P36143", "YKR058W", "P06787", "YBR109C", "Q06625", "YPR184W", "P32807", "YMR284W", "P25043", "YOR157C", "P06738", "YPR160W", "P02994", "YBR118W", "P47103", "YJR032W", "Q03957", "YKL139W", "P04806", "YFR053C", "Q12096", "YOR320C", "Q03262", "YMR278W", "P38764", "YHR027C", "Q04120", "YDR453C", "P52489", "YOR347C", "Q08723", "YOR261C", "P38930", "CKB2", "P12709", "YBR196C", "P36010", "YKL067W", "P34760", "YML028W", "P32485", "YLR113W", "P32381", "YDL029W", "P32379", "YGR253C", "P38696", "YHR129C", "P16862", "YMR205C", "P40361", "YJL070C", "P25694", "YDL126C", "P15202", "YDR256C", "P46958", "YJL146W", "P47011", "YJL137C", "Q06142", "YLR347C", "Q06103", "YPR108W", "P21954", "YDL066W", "P16861", "YGR240C", "P17709", "YCL040W", "P23724", "YBL041W", "P33401", "YKL127W", "P50094", "YML056C", "P15274", "YML035C", "P33297", "YOR117W", "Q06204", "YLR446W", "Q10740", "YNL045W", "Q03280", "YDR457W", "P38985", "YDL092W", "Q12377", "YDL097C", "P10592", "YLL024C", "P47079", "YJL008C", "P11633", "YBR089C-A", "P16892", "YBL016W", "P32769", "YKR084C", "Q06549", "YLR245C", "P15891", "YCR088W", "Q12250", "YDL147W", "P04807", "YGL253W", "P00549", "YAL038W", "P50095", "YLR432W", "Q08491", "SKI7", "P23639", "YML092C", "Q12156", "YDR063W", "P53691", "YLR216C", "P32324", "EFT2", "P38697", "YHR216W", "P02829", "YPL240C", "P05373", "YGL040C", "Q05788", "YLR209C", "P06634", "YOR204W", "P38862", "YHR171W", "P40518", "YIL062C", "Q04409", "YDR516C", "P38150", "YJL070C", "Q04062", "YDR427W", "P33299", "YKL145W", "P32464", "YKL189W", "P43599", "YFR018C", "P07267", "YPL154C", "P40016", "YER021W", "P15108", "YMR186W", "P43588", "YFR004W", "P36143", "YKR058W" ] }, "reaction_10765966": { "compartment": "compartment_7660", "id": "reaction_10765966", "reactome": "R-SCE-168136", "name": "Activated JNKs phosphorylate c-JUN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765959", "species_29358" ], "products": [ "species_10765963", "species_113582" ], "modifiers": [ [ "species_10765931", "catalyst" ] ], "additional_components": [ "YEL009C", "YEL009C", "YPR054W" ] }, "reaction_10772458": { "compartment": "compartment_70101", "id": "reaction_10772458", "reactome": "R-SCE-983162", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983036" ], "products": [ "species_983032", "species_8942986" ], "modifiers": [ [ "species_10772455", "catalyst" ] ], "additional_components": [ "P40462", "YIL137C", "P32454", "YKL157W", "P37898", "YHR047C", "Q01532", "YNL239W" ] }, "reaction_10768965": { "compartment": "compartment_70101", "id": "reaction_10768965", "reactome": "R-SCE-389756", "name": "AKT interacts and phosphorylates Cot", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768955", "species_113592" ], "products": [ "species_29370", "species_10768963" ], "modifiers": [ [ "species_10767105", "catalyst" ] ], "additional_components": [ "P25390", "YCR073C", "P53599", "YNR031C", "P25390", "YCR073C", "P53599", "YNR031C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10770645": { "compartment": "compartment_70101", "id": "reaction_10770645", "reactome": "R-SCE-450257", "name": "Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770638" ], "products": [ "species_10770643" ], "modifiers": [], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W" ] }, "reaction_10766862": { "compartment": "compartment_17951", "id": "reaction_10766862", "reactome": "R-SCE-193508", "name": "(24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193732", "species_192307" ], "products": [ "species_193465", "species_193403", "species_192305" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10786503": { "compartment": "compartment_70101", "id": "reaction_10786503", "reactome": "R-SCE-8867667", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399" ], "products": [ "species_8868400" ], "modifiers": [ [ "species_10786500", "catalyst" ] ], "additional_components": [ "P38713", "YHR073W", "Q12451", "YDL019C", "P35845", "YAR042W", "P35844", "YPL145C" ] }, "reaction_10766816": { "compartment": "compartment_70101", "id": "reaction_10766816", "reactome": "R-SCE-191983", "name": "Cholesterol is hydroxylated to 25-hydroxycholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_176478", "species_29368" ], "products": [ "species_29366", "species_192148", "species_29356" ], "modifiers": [ [ "species_10766813", "catalyst" ] ], "additional_components": [ "species_111793", "P53045", "YGR060W" ] }, "reaction_10766860": { "compartment": "compartment_17951", "id": "reaction_10766860", "reactome": "R-SCE-193455", "name": "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193422", "species_192307" ], "products": [ "species_193465", "species_192305", "species_192339" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10766864": { "compartment": "compartment_17951", "id": "reaction_10766864", "reactome": "R-SCE-193535", "name": "25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_193459" ], "products": [ "species_193732" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10766824": { "compartment": "compartment_70101", "id": "reaction_10766824", "reactome": "R-SCE-192097", "name": "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192114", "species_29360" ], "products": [ "species_70106", "species_73473", "species_192136" ], "modifiers": [ [ "species_10766821", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10766868": { "compartment": "compartment_70101", "id": "reaction_10766868", "reactome": "R-SCE-193789", "name": "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192189", "species_29360" ], "products": [ "species_70106", "species_73473", "species_193724" ], "modifiers": [ [ "species_10766821", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10786538": { "compartment": "compartment_70101", "id": "reaction_10786538", "reactome": "R-SCE-8868402", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399", "species_1806217" ], "products": [ "species_1806234", "species_8868393" ], "modifiers": [ [ "species_10786535", "catalyst" ] ], "additional_components": [ "P38713", "YHR073W", "Q12451", "YDL019C", "P35845", "YAR042W" ] }, "reaction_10766870": { "compartment": "compartment_70101", "id": "reaction_10766870", "reactome": "R-SCE-193816", "name": "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192194", "species_29360" ], "products": [ "species_70106", "species_73473", "species_193835" ], "modifiers": [ [ "species_10766821", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10766834": { "compartment": "compartment_17951", "id": "reaction_10766834", "reactome": "R-SCE-192331", "name": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192342", "species_141343" ], "products": [ "species_193422" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10766857": { "compartment": "compartment_17951", "id": "reaction_10766857", "reactome": "R-SCE-193385", "name": "Hydrolysis of choloyl-CoA to cholate and CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192356", "species_141343" ], "products": [ "species_193514", "species_193451" ], "modifiers": [ [ "species_10766854", "catalyst" ] ], "additional_components": [ "YJR019C" ] }, "reaction_10785978": { "compartment": "compartment_5683628", "id": "reaction_10785978", "reactome": "R-SCE-8854588", "name": "TBC1D25 (OATL1) binds ATG8 homologues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779200", "species_10785974" ], "products": [ "species_10785976" ], "modifiers": [], "additional_components": [ "YBL078C", "YDL234C", "P48365", "YDL234C", "P38182", "YBL078C" ] }, "reaction_10786878": { "compartment": "compartment_263163", "id": "reaction_10786878", "reactome": "R-SCE-8876193", "name": "RIC1-RGP1 exchanges GTP for GDP on RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786865", "species_29438" ], "products": [ "species_10786790", "species_10786869", "species_29420" ], "modifiers": [ [ "species_10786875", "catalyst" ] ], "additional_components": [ "species_29420", "Q99260", "YLR262C", "P39958", "YER136W", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "Q99260", "YLR262C", "species_29438", "P16664", "YDR137W", "P40395", "YLR039C" ] }, "reaction_10785971": { "compartment": "compartment_17938", "id": "reaction_10785971", "reactome": "R-SCE-8854329", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785946", "species_29356" ], "products": [ "species_10785964", "species_29372" ], "modifiers": [ [ "species_10785946", "catalyst" ], [ "species_10785969", "catalyst" ] ], "additional_components": [ "P32939", "YML001W", "CHEBI:15996", "P32939", "YML001W", "species_111349", "P32939", "YML001W", "CHEBI:15996", "YDL234C" ] }, "reaction_10785951": { "compartment": "compartment_17938", "id": "reaction_10785951", "reactome": "R-SCE-8854255", "name": "TBC1D2A accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785946", "species_29356" ], "products": [ "species_29372", "species_10785948" ], "modifiers": [ [ "species_10785946", "catalyst" ] ], "additional_components": [ "P32939", "YML001W", "CHEBI:15996", "species_29420", "P32939", "YML001W", "P32939", "YML001W", "CHEBI:15996" ] }, "reaction_10786851": { "compartment": "compartment_263163", "id": "reaction_10786851", "reactome": "R-SCE-8876190", "name": "RAB8 GEFs exchange GTP for GDP on RAB8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10786842" ], "products": [ "species_10786790", "species_10786848", "species_29420" ], "modifiers": [ [ "species_10778221", "catalyst" ] ], "additional_components": [ "species_29420", "P07560", "YFL005W", "P39958", "YER136W", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "P07560", "YFL005W", "species_29438", "YNL272C" ] }, "reaction_10785960": { "compartment": "compartment_20699", "id": "reaction_10785960", "reactome": "R-SCE-8854303", "name": "TBC1D11 binds RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785468", "species_10785956" ], "products": [ "species_10785958" ], "modifiers": [], "additional_components": [ "Q99260", "YLR262C", "species_29438", "YPL249C", "Q99260", "YLR262C", "Q12344", "YPL249C", "species_29438" ] }, "reaction_10786959": { "compartment": "compartment_13946", "id": "reaction_10786959", "reactome": "R-SCE-8877475", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10786946" ], "products": [ "species_10786790", "species_29420", "species_10786956" ], "modifiers": [ [ "species_10781391", "catalyst" ] ], "additional_components": [ "species_29420", "P39958", "YER136W", "P01123", "YFL038C", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "P01123", "YFL038C", "species_29438", "P38334", "YBR254C", "Q03630", "YML077W", "Q03784", "YDR246W", "P36149", "YKR068C", "Q04183", "YDR407C", "Q03337", "YDR472W", "Q03660", "YMR218C", "Q99394", "YOR115C" ] }, "reaction_10786801": { "compartment": "compartment_216813", "id": "reaction_10786801", "reactome": "R-SCE-8875318", "name": "RAB3 GEFs exchange GTP for GDP on RAB3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10786792" ], "products": [ "species_10786790", "species_10786796", "species_29420" ], "modifiers": [ [ "species_10786798", "catalyst" ] ], "additional_components": [ "P07560", "YFL005W", "species_29420", "P39958", "YER136W", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "P07560", "YFL005W", "species_29438", "YNL272C" ] }, "reaction_10786938": { "compartment": "compartment_17938", "id": "reaction_10786938", "reactome": "R-SCE-8877451", "name": "MON1:CCZ1 exchanges GTP for GDP on RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10786915" ], "products": [ "species_10786790", "species_10786921", "species_29420" ], "modifiers": [ [ "species_10786935", "catalyst" ] ], "additional_components": [ "species_29420", "P39958", "YER136W", "P32939", "YML001W", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "P32939", "YML001W", "species_29438", "P38273", "YBR131W", "P53129", "YGL124C" ] }, "reaction_10771192": { "compartment": "compartment_70101", "id": "reaction_10771192", "reactome": "R-SCE-727749", "name": "SLC29A3 transports nucleosides from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727782" ], "products": [ "species_727746" ], "modifiers": [ [ "species_10771189", "catalyst" ] ], "additional_components": [ "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "species_83951", "CHEBI:16704", "species_83909", "CHEBI:16750", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "species_83951", "CHEBI:16704", "species_83909", "CHEBI:16750", "YAL022C" ] }, "reaction_10764488": { "compartment": "compartment_70101", "id": "reaction_10764488", "reactome": "R-SCE-109534", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179743" ], "products": [ "species_179737" ], "modifiers": [ [ "species_10764480", "catalyst" ] ], "additional_components": [ "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83909", "CHEBI:16750", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83909", "CHEBI:16750", "YAL022C" ] }, "reaction_10765594": { "compartment": "compartment_70616", "id": "reaction_10765594", "reactome": "R-SCE-163215", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113592", "species_113581" ], "modifiers": [ [ "species_10765591", "catalyst" ] ], "additional_components": [ "P18239", "YBL030C", "P18238", "YBR085W", "P04710", "AAC1" ] }, "reaction_10764483": { "compartment": "compartment_70101", "id": "reaction_10764483", "reactome": "R-SCE-109527", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179747" ], "products": [ "species_179742" ], "modifiers": [ [ "species_10764478", "catalyst" ] ], "additional_components": [ "species_113599", "CHEBI:17821", "species_29554", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83951", "species_83909", "CHEBI:16040", "CHEBI:16750", "species_83956", "species_113599", "CHEBI:17821", "species_29554", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83951", "species_83909", "CHEBI:16040", "CHEBI:16750", "species_83956", "YAL022C" ] }, "reaction_10764485": { "compartment": "compartment_70101", "id": "reaction_10764485", "reactome": "R-SCE-109529", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179742" ], "products": [ "species_179747" ], "modifiers": [ [ "species_10764478", "catalyst" ] ], "additional_components": [ "species_113599", "CHEBI:17821", "species_29554", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83951", "species_83909", "CHEBI:16040", "CHEBI:16750", "species_83956", "species_113599", "CHEBI:17821", "species_29554", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83951", "species_83909", "CHEBI:16040", "CHEBI:16750", "species_83956", "YAL022C" ] }, "reaction_10764490": { "compartment": "compartment_70101", "id": "reaction_10764490", "reactome": "R-SCE-109536", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179737" ], "products": [ "species_179743" ], "modifiers": [ [ "species_10764480", "catalyst" ] ], "additional_components": [ "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83909", "CHEBI:16750", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83909", "CHEBI:16750", "YAL022C" ] }, "reaction_10774173": { "compartment": "compartment_5460", "id": "reaction_10774173", "reactome": "R-SCE-2162186", "name": "DeMQ10H2 is methylated to Q10H2 by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162212", "species_2162265" ], "products": [ "species_2162252", "species_2162198", "species_113529" ], "modifiers": [ [ "species_10774170", "catalyst" ] ], "additional_components": [ "YOL096C" ] }, "reaction_10774183": { "compartment": "compartment_5460", "id": "reaction_10774183", "reactome": "R-SCE-2162193", "name": "DHDB is methylated to MHDB by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162209", "species_2162265" ], "products": [ "species_2162252", "species_2162215", "species_113529" ], "modifiers": [ [ "species_10774170", "catalyst" ] ], "additional_components": [ "YOL096C" ] }, "reaction_10774197": { "compartment": "compartment_5460", "id": "reaction_10774197", "reactome": "R-SCE-2162253", "name": "FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162256", "species_2162257" ], "products": [ "species_2162214", "species_159450" ], "modifiers": [ [ "species_10774194", "catalyst" ] ], "additional_components": [ "P18900", "YBR003W", "species_109496" ] }, "reaction_10768904": { "compartment": "compartment_70101", "id": "reaction_10768904", "reactome": "R-SCE-389540", "name": "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_389545" ], "products": [ "species_70106", "species_29364", "species_113528", "species_29406" ], "modifiers": [ [ "species_10768901", "catalyst" ] ], "additional_components": [ "P21954", "YDL066W" ] }, "reaction_10773350": { "compartment": "compartment_70101", "id": "reaction_10773350", "reactome": "R-SCE-1497796", "name": "BH2 binding can lead to eNOS uncoupling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767639", "species_1497857" ], "products": [ "species_29870", "species_10773348" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "species_29870", "species_113596", "P11792", "YHR205W", "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "species_1497857", "species_29870", "P15108", "YMR186W", "species_113596", "P11792", "YHR205W" ] }, "reaction_10772915": { "compartment": "compartment_70101", "id": "reaction_10772915", "reactome": "R-SCE-1474146", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29356" ], "products": [ "species_1474124", "species_29460" ], "modifiers": [ [ "species_10772912", "catalyst" ], [ "species_29502", "catalyst" ], [ "species_29870", "inhibitor" ] ], "additional_components": [ "P51601", "YGR267C" ] }, "reaction_10774180": { "compartment": "compartment_70616", "id": "reaction_10774180", "reactome": "R-SCE-2162192", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162214", "species_2162213" ], "products": [ "species_2162207", "species_159450" ], "modifiers": [ [ "species_10774177", "catalyst" ] ], "additional_components": [] }, "reaction_10781221": { "compartment": "compartment_7660", "id": "reaction_10781221", "reactome": "R-SCE-5693566", "name": "TP53BP1 associates with H4K20Me2 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779351", "species_10774864" ], "products": [ "species_10779374" ], "modifiers": [], "additional_components": [ "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "YDR217C", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P14737", "YDR217C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10777638": { "compartment": "compartment_7660", "id": "reaction_10777638", "reactome": "R-SCE-5358513", "name": "MSH2:MSH3 binds insertion/deletion loop of 2 bases or more", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358527", "species_10777634" ], "products": [ "species_10777636" ], "modifiers": [], "additional_components": [ "P25336", "YCR092C", "species_29370", "P25847", "YOL090W", "P25336", "YCR092C", "species_29370", "P25847", "YOL090W" ] }, "reaction_10781856": { "compartment": "compartment_7660", "id": "reaction_10781856", "reactome": "R-SCE-6782211", "name": "DNA polymerases delta, epsilon or kappa bind the TC-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781852", "species_10760923", "species_10764822", "species_10781840" ], "products": [ "species_10781854" ], "modifiers": [], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P15873", "YBR088C", "P40348", "YJR068W", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P22336", "YAR007C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P06777", "YPL022W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P26754", "YNL312W", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P22336", "YAR007C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P32523", "YLL036C", "P0CH08", "RPL40A", "P07273", "YGL043W", "P38251", "YBR087W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "P28519", "YMR201C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P06777", "YPL022W", "Q04048", "YDR416W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P26754", "YNL312W", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10778491": { "compartment": "compartment_7660", "id": "reaction_10778491", "reactome": "R-SCE-5655466", "name": "USP1:WDR48 deubiquitinates monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778486" ], "products": [ "species_10778488", "species_10778482", "species_10760537" ], "modifiers": [ [ "species_10778486", "catalyst" ] ], "additional_components": [ "P38630", "YOR217W", "P40339", "YOL094C", "Q99247", "YOL087C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P36026", "YKR098C", "P26754", "YNL312W", "P25037", "YDL122W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P39967", "YER098W", "P15873", "YBR088C", "P40453", "YIL156W", "P38187", "YBL067C", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P36026", "YKR098C", "Q99247", "YOL087C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38630", "YOR217W", "P40339", "YOL094C", "Q99247", "YOL087C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P36026", "YKR098C", "P26754", "YNL312W", "P25037", "YDL122W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P39967", "YER098W", "P15873", "YBR088C", "P40453", "YIL156W", "P38187", "YBL067C" ] }, "reaction_10777795": { "compartment": "compartment_7660", "id": "reaction_10777795", "reactome": "R-SCE-5444511", "name": "Formation of MSH2:MSH3 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10777614", "species_10777632" ], "products": [ "species_10777634" ], "modifiers": [], "additional_components": [ "YOL090W", "YCR092C", "P25336", "YCR092C", "species_29370", "P25847", "YOL090W" ] }, "reaction_10779178": { "compartment": "compartment_7660", "id": "reaction_10779178", "reactome": "R-SCE-5682044", "name": "KAT5 acetylates ATM at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779173", "species_113560" ], "products": [ "species_10779175", "species_2485002" ], "modifiers": [ [ "species_10779173", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10781860": { "compartment": "compartment_7660", "id": "reaction_10781860", "reactome": "R-SCE-6782227", "name": "Ligation of newly synthesized repair patch to incised DNA in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781847" ], "products": [ "species_10781049", "species_10781858" ], "modifiers": [ [ "species_10760994", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P38251", "YBR087W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "YDL164C" ] }, "reaction_10781753": { "compartment": "compartment_7660", "id": "reaction_10781753", "reactome": "R-SCE-6781867", "name": "ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781734", "species_10760537" ], "products": [ "species_10781750" ], "modifiers": [ [ "species_10781734", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P0CH08", "RPL40A", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10764704": { "compartment": "compartment_7660", "id": "reaction_10764704", "reactome": "R-SCE-110226", "name": "Cleavage of cytosine glycol by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764701" ], "products": [ "species_110225", "species_10764694" ], "modifiers": [ [ "species_10764701", "catalyst" ] ], "additional_components": [ "Q08214", "YOL043C", "Q08214", "YOL043C", "Q08214", "YOL043C" ] }, "reaction_10764171": { "compartment": "compartment_7660", "id": "reaction_10764171", "reactome": "R-SCE-75998", "name": "Formation of RAD52 heptameric ring structure complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764167" ], "products": [ "species_10764169" ], "modifiers": [], "additional_components": [ "YML032C", "P06778", "YML032C" ] }, "reaction_10764737": { "compartment": "compartment_7660", "id": "reaction_10764737", "reactome": "R-SCE-110244", "name": "Excision of FapyG by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764734" ], "products": [ "species_10764729", "species_5636006" ], "modifiers": [ [ "species_10764734", "catalyst" ] ], "additional_components": [ "P53397", "YML060W", "P53397", "YML060W", "P53397", "YML060W" ] }, "reaction_10781817": { "compartment": "compartment_7660", "id": "reaction_10781817", "reactome": "R-SCE-6782131", "name": "ERCC2-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781803" ], "products": [ "species_113582", "species_113550", "species_10781814" ], "modifiers": [ [ "species_10781803", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10779347": { "compartment": "compartment_7660", "id": "reaction_10779347", "reactome": "R-SCE-5682983", "name": "ATM phosphorylates WHSC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779342" ], "products": [ "species_113582", "species_10779337" ], "modifiers": [ [ "species_10779342", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10779385": { "compartment": "compartment_7660", "id": "reaction_10779385", "reactome": "R-SCE-5683425", "name": "ATM phosphorylates TP53BP1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779374" ], "products": [ "species_113582", "species_10779372" ], "modifiers": [ [ "species_10779374", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P14737", "YDR217C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P14737", "YDR217C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P14737", "YDR217C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10779325": { "compartment": "compartment_7660", "id": "reaction_10779325", "reactome": "R-SCE-5682858", "name": "RNF8 and RNF168 ubiquitinate H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779300", "species_10760537" ], "products": [ "species_10779322" ], "modifiers": [ [ "species_10779300", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10764711": { "compartment": "compartment_7660", "id": "reaction_10764711", "reactome": "R-SCE-110227", "name": "Cleavage of dihydrouracil by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764708" ], "products": [ "species_30140", "species_10764694" ], "modifiers": [ [ "species_10764708", "catalyst" ] ], "additional_components": [ "Q08214", "YOL043C", "Q08214", "YOL043C", "Q08214", "YOL043C" ] }, "reaction_10779340": { "compartment": "compartment_7660", "id": "reaction_10779340", "reactome": "R-SCE-5682965", "name": "WHSC1 dimethylates histone H4 on lysine K21 at DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779337", "species_77087" ], "products": [ "species_10779251", "species_77502" ], "modifiers": [ [ "species_10779337", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10779472": { "compartment": "compartment_7660", "id": "reaction_10779472", "reactome": "R-SCE-5685230", "name": "CHEK1 phosphorylates RAD51", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779467", "species_29358" ], "products": [ "species_113582", "species_10779470" ], "modifiers": [ [ "species_10761086", "catalyst" ] ], "additional_components": [ "YER095W", "YER095W", "P36002", "YKL198C", "P47116", "YJR059W", "P06782", "YDR477W" ] }, "reaction_10777660": { "compartment": "compartment_7660", "id": "reaction_10777660", "reactome": "R-SCE-5358597", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777656", "species_10777640" ], "products": [ "species_10777658" ], "modifiers": [], "additional_components": [ "YOR033C", "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W", "P14242", "YNL082W", "P38920", "YMR167W", "P39875", "YOR033C", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W" ] }, "reaction_10763954": { "compartment": "compartment_7660", "id": "reaction_10763954", "reactome": "R-SCE-75172", "name": "Formation of RAD50:MRE11 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763950", "species_981774" ], "products": [ "species_10763952" ], "modifiers": [], "additional_components": [ "P32829", "MRE11", "P12753", "DNA repair protein RAD50" ] }, "reaction_10777627": { "compartment": "compartment_7660", "id": "reaction_10777627", "reactome": "R-SCE-5358510", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777623", "species_10777609", "species_10760934" ], "products": [ "species_10777625" ], "modifiers": [], "additional_components": [ "species_113592", "Q03834", "YDR097C", "P25847", "YOL090W", "P14242", "YNL082W", "P38920", "YMR167W", "P15873", "YBR088C", "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W" ] }, "reaction_10779284": { "compartment": "compartment_7660", "id": "reaction_10779284", "reactome": "R-SCE-5682607", "name": "PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10779267" ], "products": [ "species_10774805", "species_10779281" ], "modifiers": [ [ "species_10779267", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "YDL064W", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10781725": { "compartment": "compartment_7660", "id": "reaction_10781725", "reactome": "R-SCE-6781840", "name": "ERCC6 binds stalled RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781721", "species_10781713" ], "products": [ "species_10781723" ], "modifiers": [], "additional_components": [ "YJR035W", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P20434", "RPB5", "P40352", "YJR035W", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10779259": { "compartment": "compartment_7660", "id": "reaction_10779259", "reactome": "R-SCE-5682588", "name": "RNF8 binds phosphorylated MDC1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779220", "species_10779255" ], "products": [ "species_10779257" ], "modifiers": [], "additional_components": [ "P53924", "YNL116W", "species_158417", "P32829", "MRE11", "P46995", "YJL168C", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10764718": { "compartment": "compartment_7660", "id": "reaction_10764718", "reactome": "R-SCE-110229", "name": "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764715" ], "products": [ "species_5637659", "species_10764694" ], "modifiers": [ [ "species_10764715", "catalyst" ] ], "additional_components": [ "Q08214", "YOL043C", "Q08214", "YOL043C", "Q08214", "YOL043C" ] }, "reaction_10779296": { "compartment": "compartment_7660", "id": "reaction_10779296", "reactome": "R-SCE-5682629", "name": "HERC2 facilitates UBE2N:UBE2V2 binding to RNF8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779290", "species_10779281" ], "products": [ "species_10779294" ], "modifiers": [], "additional_components": [ "P53152", "MMS2", "P52490", "UBC13", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10778520": { "compartment": "compartment_7660", "id": "reaction_10778520", "reactome": "R-SCE-5655483", "name": "USP1 autocleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778482" ], "products": [ "species_10778480", "species_10778517", "species_10778505" ], "modifiers": [ [ "species_10778482", "catalyst" ] ], "additional_components": [ "P36026", "YKR098C", "Q99247", "YOL087C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "YOL087C", "P36026", "YKR098C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "P36026", "YKR098C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "P36026", "YKR098C", "Q99247", "YOL087C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C" ] }, "reaction_10779349": { "compartment": "compartment_7660", "id": "reaction_10779349", "reactome": "R-SCE-5682992", "name": "KDM4A,B bind H4K20Me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779253", "species_10779251" ], "products": [ "species_10779255" ], "modifiers": [], "additional_components": [ "Q03833", "YDR096W", "P39956", "YER169W", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10781843": { "compartment": "compartment_7660", "id": "reaction_10781843", "reactome": "R-SCE-6782204", "name": "5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781838" ], "products": [ "species_10781840" ], "modifiers": [ [ "species_10781838", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P06777", "YPL022W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P22336", "YAR007C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P06777", "YPL022W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P26754", "YNL312W", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P06777", "YPL022W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10781711": { "compartment": "compartment_7660", "id": "reaction_10781711", "reactome": "R-SCE-6781818", "name": "RNA Pol II initiates transcription from damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762310", "species_5688114", "species_10763293" ], "products": [ "species_10781709" ], "modifiers": [], "additional_components": [ "P20433", "YJL140W", "P20434", "RPB5", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P20435", "RPO26", "P04050", "YDL140C", "P40422", "RPC10", "P38902", "YOL005C", "P34087", "YDR404C", "P22139", "RPB10", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10781209": { "compartment": "compartment_7660", "id": "reaction_10781209", "reactome": "R-SCE-5693536", "name": "ATM phosphorylates MDC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781206" ], "products": [ "species_113582", "species_10779335" ], "modifiers": [ [ "species_10781206", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10764732": { "compartment": "compartment_7660", "id": "reaction_10764732", "reactome": "R-SCE-110243", "name": "Excision of 8-oxoguanine by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764727" ], "products": [ "species_10764729", "species_110242" ], "modifiers": [ [ "species_10764727", "catalyst" ] ], "additional_components": [ "P53397", "YML060W", "P53397", "YML060W", "P53397", "YML060W" ] }, "reaction_10781219": { "compartment": "compartment_7660", "id": "reaction_10781219", "reactome": "R-SCE-5693549", "name": "ATM phosphorylates histone H2AFX on S139 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781216" ], "products": [ "species_113582", "species_10779442" ], "modifiers": [ [ "species_10781216", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10781716": { "compartment": "compartment_7660", "id": "reaction_10781716", "reactome": "R-SCE-6781824", "name": "Active RNA Pol II complex transcribes lesion-containing DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781709", "species_6781829" ], "products": [ "species_10781713", "species_113541" ], "modifiers": [ [ "species_10781709", "catalyst" ] ], "additional_components": [ "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10788944": { "compartment": "compartment_70101", "id": "reaction_10788944", "reactome": "R-SCE-9656947", "name": "OGG1beta translocates to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788940" ], "products": [ "species_10788942" ], "modifiers": [], "additional_components": [ "YML060W", "YML060W" ] }, "reaction_10777662": { "compartment": "compartment_7660", "id": "reaction_10777662", "reactome": "R-SCE-5358912", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10777647" ], "products": [ "species_113582", "species_10777623" ], "modifiers": [], "additional_components": [ "species_29370", "Q03834", "YDR097C", "P25847", "YOL090W", "species_113592", "Q03834", "YDR097C", "P25847", "YOL090W" ] }, "reaction_10781224": { "compartment": "compartment_7660", "id": "reaction_10781224", "reactome": "R-SCE-5693598", "name": "ATM phosphorylates NBN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781211" ], "products": [ "species_113582", "species_10779232" ], "modifiers": [ [ "species_10781211", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10779344": { "compartment": "compartment_7660", "id": "reaction_10779344", "reactome": "R-SCE-5682967", "name": "WHSC1 binds DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776856", "species_10779335" ], "products": [ "species_10779342" ], "modifiers": [], "additional_components": [ "YJL168C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10779366": { "compartment": "compartment_7660", "id": "reaction_10779366", "reactome": "R-SCE-5683077", "name": "RNF8 and RNF168 ubiquitinate KDM4A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779322", "species_10760537" ], "products": [ "species_10779351", "species_10779363" ], "modifiers": [ [ "species_10779322", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "Q03833", "YDR096W", "P39956", "YER169W", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10781240": { "compartment": "compartment_7660", "id": "reaction_10781240", "reactome": "R-SCE-5693602", "name": "ATM recognizes H2AFX-Nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779432", "species_10779232" ], "products": [ "species_10781216" ], "modifiers": [], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10764697": { "compartment": "compartment_7660", "id": "reaction_10764697", "reactome": "R-SCE-110224", "name": "Cleavage of thymine glycol by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764692" ], "products": [ "species_110223", "species_10764694" ], "modifiers": [ [ "species_10764692", "catalyst" ] ], "additional_components": [ "Q08214", "YOL043C", "Q08214", "YOL043C", "Q08214", "YOL043C" ] }, "reaction_10781214": { "compartment": "compartment_7660", "id": "reaction_10781214", "reactome": "R-SCE-5693540", "name": "MRN activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779175", "species_29358" ], "products": [ "species_113582", "species_10781211", "species_10768327" ], "modifiers": [ [ "species_10779175", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10764681": { "compartment": "compartment_7660", "id": "reaction_10764681", "reactome": "R-SCE-110215", "name": "Cleavage of uracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764674" ], "products": [ "species_29554", "species_10764678" ], "modifiers": [ [ "species_10764674", "catalyst" ] ], "additional_components": [ "P12887", "YML021C", "P12887", "YML021C", "P12887", "YML021C" ] }, "reaction_10777649": { "compartment": "compartment_7660", "id": "reaction_10777649", "reactome": "R-SCE-5358525", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358514", "species_10777645" ], "products": [ "species_10777647" ], "modifiers": [], "additional_components": [ "species_29370", "Q03834", "YDR097C", "P25847", "YOL090W", "species_29370", "Q03834", "YDR097C", "P25847", "YOL090W" ] }, "reaction_10777799": { "compartment": "compartment_7660", "id": "reaction_10777799", "reactome": "R-SCE-5444523", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777607", "species_10777602" ], "products": [ "species_10777609" ], "modifiers": [], "additional_components": [ "YNL082W", "YMR167W", "P14242", "YNL082W", "P38920", "YMR167W" ] }, "reaction_10779382": { "compartment": "compartment_7660", "id": "reaction_10779382", "reactome": "R-SCE-5683405", "name": "PPP5C dephosphorylates TP53BP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10779372" ], "products": [ "species_113550", "species_10779374" ], "modifiers": [ [ "species_10779379", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P14737", "YDR217C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P14737", "YDR217C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "YGR123C" ] }, "reaction_10781806": { "compartment": "compartment_7660", "id": "reaction_10781806", "reactome": "R-SCE-6782069", "name": "UVSSA:USP7 deubiquitinates ERCC6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781797", "species_113518" ], "products": [ "species_10781803", "species_10760537" ], "modifiers": [ [ "species_10781797", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10781850": { "compartment": "compartment_7660", "id": "reaction_10781850", "reactome": "R-SCE-6782208", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781845", "species_30555" ], "products": [ "species_10781847", "species_113541" ], "modifiers": [ [ "species_10781845", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P38251", "YBR087W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P38251", "YBR087W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P38251", "YBR087W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10777797": { "compartment": "compartment_7660", "id": "reaction_10777797", "reactome": "R-SCE-5444516", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10777619", "species_10777614" ], "products": [ "species_10777645" ], "modifiers": [], "additional_components": [ "YDR097C", "YOL090W", "species_29370", "Q03834", "YDR097C", "P25847", "YOL090W" ] }, "reaction_10777643": { "compartment": "compartment_7660", "id": "reaction_10777643", "reactome": "R-SCE-5358518", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777625" ], "products": [ "species_10777640" ], "modifiers": [ [ "species_10777625", "catalyst" ] ], "additional_components": [ "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W", "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W", "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W" ] }, "reaction_10789082": { "compartment": "compartment_7660", "id": "reaction_10789082", "reactome": "R-SCE-9684118", "name": "ERCC3-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781814" ], "products": [ "species_113582", "species_113550", "species_10781825" ], "modifiers": [ [ "species_10781814", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10779270": { "compartment": "compartment_7660", "id": "reaction_10779270", "reactome": "R-SCE-5682598", "name": "ATM phosphorylates HERC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779263" ], "products": [ "species_113582", "species_10779267" ], "modifiers": [ [ "species_10779263", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10777651": { "compartment": "compartment_7660", "id": "reaction_10777651", "reactome": "R-SCE-5358592", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358610", "species_29358" ], "products": [ "species_109966", "species_164121", "species_113541" ], "modifiers": [ [ "species_10760994", "catalyst" ] ], "additional_components": [ "YDL164C" ] }, "reaction_10778493": { "compartment": "compartment_7660", "id": "reaction_10778493", "reactome": "R-SCE-5655481", "name": "USP1:WDR48 binds monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778484", "species_10778482" ], "products": [ "species_10778486" ], "modifiers": [], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P36026", "YKR098C", "Q99247", "YOL087C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "P38630", "YOR217W", "P40339", "YOL094C", "Q99247", "YOL087C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P36026", "YKR098C", "P26754", "YNL312W", "P25037", "YDL122W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P39967", "YER098W", "P15873", "YBR088C", "P40453", "YIL156W", "P38187", "YBL067C" ] }, "reaction_10764688": { "compartment": "compartment_7660", "id": "reaction_10764688", "reactome": "R-SCE-110217", "name": "Cleavage of 5-hydroxyluracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764685" ], "products": [ "species_10764678", "species_110216" ], "modifiers": [ [ "species_10764685", "catalyst" ] ], "additional_components": [ "P12887", "YML021C", "P12887", "YML021C", "P12887", "YML021C" ] }, "reaction_10777996": { "compartment": "compartment_70101", "id": "reaction_10777996", "reactome": "R-SCE-5618331", "name": "HDAC6 deacetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_10777993" ], "products": [ "species_10768744", "species_76183" ], "modifiers": [ [ "species_10777457", "catalyst" ] ], "additional_components": [ "P09734", "YML124C", "species_29420", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "species_29420", "P09734", "YML124C", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "YNL021W" ] }, "reaction_10778225": { "compartment": "compartment_13949", "id": "reaction_10778225", "reactome": "R-SCE-5638014", "name": "RAB11A:GTP-containing Golgi vesicles recruit RAB3IP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778216", "species_10778221" ], "products": [ "species_10778223" ], "modifiers": [], "additional_components": [ "P51996", "YGL210W", "P38555", "YER031C", "species_29438", "YNL272C", "P51996", "YGL210W", "P38555", "YER031C", "species_29438", "P17065", "YNL272C" ] }, "reaction_10787471": { "compartment": "compartment_70616", "id": "reaction_10787471", "reactome": "R-SCE-8949580", "name": "F1Fo ATP synthase dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765816" ], "products": [ "species_10787469" ], "modifiers": [], "additional_components": [ "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W" ] }, "reaction_10761323": { "compartment": "compartment_70101", "id": "reaction_10761323", "reactome": "R-SCE-70475", "name": "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10761318", "catalyst" ] ], "additional_components": [ "P12709", "YBR196C" ] }, "reaction_10778180": { "compartment": "compartment_70101", "id": "reaction_10778180", "reactome": "R-SCE-5631885", "name": "PRDX1 overoxidizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29408", "species_10778172" ], "products": [ "species_29356", "species_10778177" ], "modifiers": [ [ "species_10778172", "catalyst" ] ], "additional_components": [ "P34760", "YML028W", "P34760", "YML028W", "P34760", "YML028W" ] }, "reaction_10762082": { "compartment": "compartment_70101", "id": "reaction_10762082", "reactome": "R-SCE-71682", "name": "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_111745" ], "products": [ "species_29366", "species_29450" ], "modifiers": [ [ "species_10762079", "catalyst" ] ], "additional_components": [ "P41921", "YPL091W", "species_113596" ] }, "reaction_10761172": { "compartment": "compartment_70101", "id": "reaction_10761172", "reactome": "R-SCE-70377", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_30537" ], "products": [ "species_70106", "species_29364", "species_31467" ], "modifiers": [ [ "species_10761169", "catalyst" ] ], "additional_components": [ "species_29366", "P11412", "YNL241C" ] }, "reaction_10771975": { "compartment": "compartment_20699", "id": "reaction_10771975", "reactome": "R-SCE-964737", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_915149" ], "products": [ "species_964740", "species_964752" ], "modifiers": [ [ "species_10771968", "catalyst" ] ], "additional_components": [ "YLR057W" ] }, "reaction_10777597": { "compartment": "compartment_70101", "id": "reaction_10777597", "reactome": "R-SCE-5358494", "name": "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777577", "species_71284" ], "products": [ "species_10777564", "species_353106" ], "modifiers": [ [ "species_10777594", "catalyst" ] ], "additional_components": [ "P32461", "YKL191W", "P40487", "YIL103W", "Q3E840", "YBL071W-A" ] }, "reaction_10769136": { "compartment": "compartment_70101", "id": "reaction_10769136", "reactome": "R-SCE-391266", "name": "Association of CCT/TriC with sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769132", "species_10769088" ], "products": [ "species_10769134" ], "modifiers": [], "additional_components": [ "P39079", "YDR188W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "YLR260W", "P39079", "YDR188W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "Q06147", "YLR260W" ] }, "reaction_10784720": { "compartment": "compartment_20699", "id": "reaction_10784720", "reactome": "R-SCE-6809015", "name": "NSF ATPase activity dissociates cis-SNARE at cis-Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10784715" ], "products": [ "species_10784697", "species_10784688", "species_10784699", "species_10784683", "species_29372", "species_10784703", "species_10784707" ], "modifiers": [ [ "species_10784715", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W", "P22804", "YIL004C", "P43682", "YKL006C-A", "YHL031C", "YLR026C", "YKL196C", "YLR078C", "YIL004C", "P25385", "YLR078C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W" ] }, "reaction_10776520": { "compartment": "compartment_12045", "id": "reaction_10776520", "reactome": "R-SCE-4419978", "name": "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4419987", "species_191362" ], "products": [ "species_4419982" ], "modifiers": [ [ "species_10776517", "catalyst" ] ], "additional_components": [ "Q12063", "YDL193W", "P35196", "YBR002C" ] }, "reaction_10765434": { "compartment": "compartment_70101", "id": "reaction_10765434", "reactome": "R-SCE-156930", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10765430" ], "products": [ "species_10765432" ], "modifiers": [], "additional_components": [ "P32324", "EFT2", "species_29438" ] }, "reaction_10774887": { "compartment": "compartment_7660", "id": "reaction_10774887", "reactome": "R-SCE-2997723", "name": "PIAS4 SUMOylates TP53BP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10774864" ], "products": [ "species_10774872", "species_10774805" ], "modifiers": [ [ "species_10774884", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDR217C", "Q12306", "YDR510W", "P14737", "YDR217C", "YDL064W", "Q04195", "YDR409W", "Q12216", "YOR156C" ] }, "reaction_10781067": { "compartment": "compartment_70101", "id": "reaction_10781067", "reactome": "R-SCE-5691431", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766135" ], "products": [ "species_10766133" ], "modifiers": [ [ "species_10760639", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YFR004W" ] }, "reaction_10786777": { "compartment": "compartment_70101", "id": "reaction_10786777", "reactome": "R-SCE-8870469", "name": "RGGT geranylgeranylates RAB proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786641", "species_1131164" ], "products": [ "species_10786772", "species_111294", "species_10786774" ], "modifiers": [ [ "species_10786641", "catalyst" ] ], "additional_components": [ "Q99260", "YLR262C", "species_1131164", "P32864", "YOR370C", "Q00618", "YJL031C", "P36017", "YOR089C", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P20133", "YPR176C", "P48559", "YNL304W", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "Q99260", "YLR262C", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P32864", "YOR370C", "P48559", "YNL304W", "P36017", "YOR089C", "species_1131164", "P20133", "YPR176C", "Q00618", "YJL031C", "Q99260", "YLR262C", "species_1131164", "P32864", "YOR370C", "Q00618", "YJL031C", "P36017", "YOR089C", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P20133", "YPR176C", "P48559", "YNL304W" ] }, "reaction_10787662": { "compartment": "compartment_17947", "id": "reaction_10787662", "reactome": "R-SCE-8953917", "name": "PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787654", "species_10787658" ], "products": [ "species_10787660" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "Q05568", "YDR265W", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "Q04370", "YMR026C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05568", "YDR265W" ] }, "reaction_10765525": { "compartment": "compartment_12045", "id": "reaction_10765525", "reactome": "R-SCE-162873", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855663", "species_449229" ], "products": [ "species_162872", "species_8855667" ], "modifiers": [ [ "species_10765522", "catalyst" ] ], "additional_components": [ "YBR004C" ] }, "reaction_10770358": { "compartment": "compartment_70101", "id": "reaction_10770358", "reactome": "R-SCE-446185", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449703" ], "products": [ "species_532204" ], "modifiers": [ [ "species_10770355", "catalyst" ] ], "additional_components": [ "YEL058W" ] }, "reaction_10768034": { "compartment": "compartment_70101", "id": "reaction_10768034", "reactome": "R-SCE-204662", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10767990", "species_29368" ], "products": [ "species_10768024", "species_29360", "species_29356" ], "modifiers": [ [ "species_10768031", "catalyst" ] ], "additional_components": [ "P19211", "YJR047C", "P23301", "YEL034W", "P19211", "YJR047C", "P23301", "YEL034W", "P47120", "YJR070C", "species_111793" ] }, "reaction_10787059": { "compartment": "compartment_7660", "id": "reaction_10787059", "reactome": "R-SCE-8932221", "name": "METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10775766" ], "products": [ "species_10787051", "species_77502" ], "modifiers": [ [ "species_10787056", "catalyst" ] ], "additional_components": [ "YLL024C", "YLL024C", "YNL024C" ] }, "reaction_10785932": { "compartment": "compartment_70101", "id": "reaction_10785932", "reactome": "R-SCE-8853529", "name": "OTULIN,USP5 cleaves UBB yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785930" ], "products": [ "species_10760584", "species_10760576", "species_10760568" ], "modifiers": [ [ "species_10780500", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YBR058C" ] }, "reaction_10776349": { "compartment": "compartment_7660", "id": "reaction_10776349", "reactome": "R-SCE-3900177", "name": "SUMOylation of DDX5 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776339" ], "products": [ "species_10774805", "species_10776347" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YNL112W", "YDL064W", "P24783", "YNL112W", "Q12306", "YDR510W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10772580": { "compartment": "compartment_70101", "id": "reaction_10772580", "reactome": "R-SCE-1022127", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772576" ], "products": [ "species_10772578" ], "modifiers": [], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "species_915149", "CHEBI:60627", "P05759", "RPS31", "species_964740", "CHEBI:60629", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "CHEBI:60628" ] }, "reaction_10770374": { "compartment": "compartment_17957", "id": "reaction_10770374", "reactome": "R-SCE-446189", "name": "Addition of a second glucose to the N-glycan precursor by ALG8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449649", "species_532542" ], "products": [ "species_449311", "species_449638" ], "modifiers": [ [ "species_10770371", "catalyst" ] ], "additional_components": [ "YOR067C" ] }, "reaction_10776364": { "compartment": "compartment_7660", "id": "reaction_10776364", "reactome": "R-SCE-3968362", "name": "SUMOylation of PIAS4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10774884" ], "products": [ "species_10776362", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "Q04195", "YDR409W", "Q12216", "YOR156C", "Q04195", "YDR409W", "Q12216", "YOR156C", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10781491": { "compartment": "compartment_6791047", "id": "reaction_10781491", "reactome": "R-SCE-5694425", "name": "NSF ATPase activity dissociates cis-SNARE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10781486" ], "products": [ "species_10781458", "species_10781451", "species_10769994", "species_10781444", "species_10781474", "species_10781482", "species_29372", "species_10781453" ], "modifiers": [ [ "species_10781486", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P22804", "YIL004C", "P22213", "YDR189W", "P36015", "YKL196C", "P32854", "YOR036W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W", "YDR189W", "YIL004C", "YBL050W", "P18759", "YBR080C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P32854", "YOR036W", "P36015", "YKL196C", "P22214", "YLR268W", "YLR078C", "P25385", "YLR078C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P22804", "YIL004C", "P22213", "YDR189W", "P36015", "YKL196C", "P32854", "YOR036W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W" ] }, "reaction_10776337": { "compartment": "compartment_7660", "id": "reaction_10776337", "reactome": "R-SCE-3900047", "name": "SUMOylation of DDX17 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776327", "species_10774813" ], "products": [ "species_10776335", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "YNL112W", "P50623", "YDL064W", "Q12306", "YDR510W", "P24783", "YNL112W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10785870": { "compartment": "compartment_70101", "id": "reaction_10785870", "reactome": "R-SCE-8852134", "name": "UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760634", "species_113592", "species_10772385" ], "products": [ "species_111294", "species_10785770" ], "modifiers": [ [ "species_10772385", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YKL210W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YKL210W" ] }, "reaction_10768010": { "compartment": "compartment_70101", "id": "reaction_10768010", "reactome": "R-SCE-204617", "name": "DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10767990", "species_204628" ], "products": [ "species_29360", "species_204635", "species_10768000" ], "modifiers": [ [ "species_10768007", "catalyst" ] ], "additional_components": [ "P19211", "YJR047C", "P23301", "YEL034W", "P19211", "YJR047C", "P23301", "YEL034W", "P38791", "YHR068W" ] }, "reaction_10770366": { "compartment": "compartment_17957", "id": "reaction_10770366", "reactome": "R-SCE-446188", "name": "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449298", "species_449229" ], "products": [ "species_449311", "species_449315" ], "modifiers": [ [ "species_10770363", "catalyst" ] ], "additional_components": [ "YBL082C" ] }, "reaction_10762154": { "compartment": "compartment_70101", "id": "reaction_10762154", "reactome": "R-SCE-71732", "name": "PPA1 hydrolyzes pyrophosphate to orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294", "species_29356" ], "products": [ "species_29372" ], "modifiers": [ [ "species_10762151", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P28239", "YMR267W", "P00817", "YBR011C" ] }, "reaction_10763035": { "compartment": "compartment_70101", "id": "reaction_10763035", "reactome": "R-SCE-72671", "name": "eIF5B:GTP is hydrolyzed and released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763029" ], "products": [ "species_10763031", "species_10763033", "species_29372" ], "modifiers": [], "additional_components": [ "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "P39730", "YAL035W", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B", "species_29420", "P39730", "YAL035W", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B" ] }, "reaction_10774923": { "compartment": "compartment_7660", "id": "reaction_10774923", "reactome": "R-SCE-3000434", "name": "PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774893", "species_10774813" ], "products": [ "species_10774805", "species_10774906" ], "modifiers": [ [ "species_10774920", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "Q12306", "YDR510W", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q04195", "YDR409W", "Q12216", "YOR156C" ] }, "reaction_10785859": { "compartment": "compartment_7660", "id": "reaction_10785859", "reactome": "R-SCE-8852130", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785838", "species_10785824" ], "products": [ "species_10785686", "species_10785857" ], "modifiers": [], "additional_components": [ "P52492", "YOR339C", "P15731", "YBR082C", "P15732", "YDR059C", "P06104", "YGL058W", "P14682", "YDR054C", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52492", "YOR339C", "P15731", "YBR082C", "P05759", "RPS31", "P15732", "YDR059C", "P06104", "YGL058W", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10787096": { "compartment": "compartment_70101", "id": "reaction_10787096", "reactome": "R-SCE-8932413", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10765400" ], "products": [ "species_71285", "species_10787088" ], "modifiers": [ [ "species_10787093", "catalyst" ] ], "additional_components": [ "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "YIL064W" ] }, "reaction_10776706": { "compartment": "compartment_7660", "id": "reaction_10776706", "reactome": "R-SCE-4641342", "name": "SUMOylation of TOP2A with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776696", "species_10774813" ], "products": [ "species_10776704", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "YNL088W", "P50623", "YDL064W", "Q12306", "YDR510W", "P06786", "YNL088W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10777327": { "compartment": "compartment_7660", "id": "reaction_10777327", "reactome": "R-SCE-5228523", "name": "RANBP2 SUMOylates MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774893", "species_10774813" ], "products": [ "species_10774805", "species_10774906" ], "modifiers": [ [ "species_10763942", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "Q12306", "YDR510W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P40066", "YER107C", "Q02455", "YKR095W", "P36161", "YKR082W", "P52891", "YDL116W", "P38181", "YBL079W", "P53011", "YGL100W", "P20676", "YOR098C", "P47054", "YJL039C", "Q02630", "YMR047C", "P40368", "YJL061W", "Q04491", "YLR208W", "Q05166", "YDL088C", "P46673", "YJR042W", "P48837", "YGR119C", "P34077", "YFR002W", "P14907", "YJL041W", "P52593", "YML103C", "P35729", "YKL057C", "P32500", "YML031W", "P41920", "YDR002W" ] }, "reaction_10776585": { "compartment": "compartment_7660", "id": "reaction_10776585", "reactome": "R-SCE-4570467", "name": "SUMOylation of NOP58 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776574" ], "products": [ "species_10774805", "species_10776583" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "Q12306", "YDR510W", "Q12499", "NOP58", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10784643": { "compartment": "compartment_6791047", "id": "reaction_10784643", "reactome": "R-SCE-6807877", "name": "ARFGAPs stimulate ARF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784546" ], "products": [ "species_10784367", "species_10784640", "species_10784463", "species_10784385" ], "modifiers": [ [ "species_10784546", "catalyst" ] ], "additional_components": [ "P32803", "YGL200C", "P25386", "YDL058W", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "P22804", "YIL004C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P36015", "YKL196C", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P32803", "YGL200C", "P25386", "YDL058W", "P53198", "YGL002W", "P22804", "YIL004C", "P39704", "YAL007C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P43621", "YFR051C", "P53600", "YPL010W", "P01123", "YFL038C", "P53622", "YDL145C", "Q12403", "YDL018C", "P40509", "YIL076W", "P36015", "YKL196C", "P32074", "YNL287W", "P41811", "YGL137W", "P32572", "YNL204C", "P38682", "YER122C", "P35197", "YDL226C", "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "P32803", "YGL200C", "P25386", "YDL058W", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "P22804", "YIL004C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P36015", "YKL196C", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C" ] }, "reaction_10770382": { "compartment": "compartment_12045", "id": "reaction_10770382", "reactome": "R-SCE-446191", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449299", "species_162756" ], "products": [ "species_109402", "species_449222" ], "modifiers": [ [ "species_10770379", "catalyst" ] ], "additional_components": [ "YBR243C" ] }, "reaction_10776642": { "compartment": "compartment_7660", "id": "reaction_10776642", "reactome": "R-SCE-4615872", "name": "RANBP2 SUMOylates HDAC4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776632" ], "products": [ "species_10776640", "species_10774805" ], "modifiers": [ [ "species_10763942", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YNL021W", "Q12306", "YDR510W", "P53973", "YNL021W", "YDL064W", "P40066", "YER107C", "Q02455", "YKR095W", "P36161", "YKR082W", "P52891", "YDL116W", "P38181", "YBL079W", "P53011", "YGL100W", "P20676", "YOR098C", "P47054", "YJL039C", "Q02630", "YMR047C", "P40368", "YJL061W", "Q04491", "YLR208W", "Q05166", "YDL088C", "P46673", "YJR042W", "P48837", "YGR119C", "P34077", "YFR002W", "P14907", "YJL041W", "P52593", "YML103C", "P35729", "YKL057C", "P32500", "YML031W", "P41920", "YDR002W" ] }, "reaction_10765517": { "compartment": "compartment_70101", "id": "reaction_10765517", "reactome": "R-SCE-162857", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855657", "species_29356" ], "products": [ "species_29416", "species_8855661" ], "modifiers": [ [ "species_10765514", "catalyst" ] ], "additional_components": [ "YMR281W" ] }, "reaction_10770615": { "compartment": "compartment_5460", "id": "reaction_10770615", "reactome": "R-SCE-449937", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_159450" ], "products": [ "species_113548" ], "modifiers": [ [ "species_10770612", "catalyst" ], [ "species_109496", "catalyst" ] ], "additional_components": [ "P00817", "YBR011C" ] }, "reaction_10765380": { "compartment": "compartment_70101", "id": "reaction_10765380", "reactome": "R-SCE-156823", "name": "Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765355", "species_10765376" ], "products": [ "species_10765378" ], "modifiers": [], "additional_components": [ "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38760", "YHR015W", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "P04147", "YER165W", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P39684", "YFR023W", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38760", "YHR015W", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "P04147", "YER165W", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P39684", "YFR023W", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P26784", "RPL16A", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C" ] }, "reaction_10776408": { "compartment": "compartment_7660", "id": "reaction_10776408", "reactome": "R-SCE-4085350", "name": "SUMOylation of UBE2I with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10774805" ], "products": [ "species_10776406", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10787608": { "compartment": "compartment_70101", "id": "reaction_10787608", "reactome": "R-SCE-8952618", "name": "AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787593" ], "products": [ "species_10787605", "species_10787548" ], "modifiers": [ [ "species_10787593", "catalyst" ] ], "additional_components": [ "Q12395", "YLR128W", "P13365", "YAL040C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P24868", "YGR108W", "Q04511", "YML088W", "P20438", "YPL256C", "P32943", "YGR109C", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P52491", "YLR306W", "P36037", "YKL213C", "Q12347", "YLR097C", "Q03919", "YDR139C", "Q12395", "YLR128W", "P13365", "YAL040C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P24868", "YGR108W", "Q04511", "YML088W", "P20438", "YPL256C", "P32943", "YGR109C", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03919", "YDR139C", "P36037", "YKL213C", "Q12347", "YLR097C", "YLR306W", "Q12395", "YLR128W", "P13365", "YAL040C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P24868", "YGR108W", "Q04511", "YML088W", "P20438", "YPL256C", "P32943", "YGR109C", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P52491", "YLR306W", "P36037", "YKL213C", "Q12347", "YLR097C", "Q03919", "YDR139C" ] }, "reaction_10773656": { "compartment": "compartment_70101", "id": "reaction_10773656", "reactome": "R-SCE-1799332", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773652", "species_10773650" ], "products": [ "species_10773654" ], "modifiers": [], "additional_components": [ "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B", "P38687", "YPL243W", "P32342", "YKL122C", "P38688", "YPL210C", "P29478", "YML105C", "P38985", "YDL092W", "P20424", "YPR088C", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29478", "YML105C", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P20424", "YPR088C", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P38687", "YPL243W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P32342", "YKL122C", "P38688", "YPL210C", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "P38985", "YDL092W", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B" ] }, "reaction_10777561": { "compartment": "compartment_70101", "id": "reaction_10777561", "reactome": "R-SCE-5358475", "name": "DPH6 ligates ammonium to diphthine-EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_31633", "species_10777553" ], "products": [ "species_10765430", "species_111294", "species_76577" ], "modifiers": [ [ "species_10777558", "catalyst" ] ], "additional_components": [ "YLR143W" ] }, "reaction_10786576": { "compartment": "compartment_70101", "id": "reaction_10786576", "reactome": "R-SCE-8870465", "name": "RGGT binds the RAB-binding subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786568", "species_10784093", "species_1131164" ], "products": [ "species_10786574" ], "modifiers": [], "additional_components": [ "P20133", "YPR176C", "Q00618", "YJL031C", "YOR370C", "species_1131164", "P32864", "YOR370C", "P20133", "YPR176C", "Q00618", "YJL031C" ] }, "reaction_10775215": { "compartment": "compartment_7660", "id": "reaction_10775215", "reactome": "R-SCE-3232162", "name": "PIAS3 SUMOylates MITF with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10775197" ], "products": [ "species_10774805", "species_10775206" ], "modifiers": [ [ "species_10775212", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YBL103C", "YDL064W", "P38165", "YBL103C", "Q12306", "YDR510W", "Q04195", "YDR409W", "Q12216", "YOR156C" ] }, "reaction_10762699": { "compartment": "compartment_70101", "id": "reaction_10762699", "reactome": "R-SCE-72663", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10762638" ], "products": [ "species_10762640" ], "modifiers": [], "additional_components": [ "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438" ] }, "reaction_10787672": { "compartment": "compartment_17947", "id": "reaction_10787672", "reactome": "R-SCE-8953946", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787660" ], "products": [ "species_10772640", "species_10787669" ], "modifiers": [ [ "species_10787660", "catalyst" ] ], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "Q04370", "YMR026C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05568", "YDR265W", "P15731", "YBR082C", "P15732", "YDR059C", "P35056", "phospho-PEX5", "P53112", "PEX14", "P05759", "RPS31", "P80667", "PEX13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q04370", "YMR026C", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "Q04370", "YMR026C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05568", "YDR265W" ] }, "reaction_10770406": { "compartment": "compartment_12045", "id": "reaction_10770406", "reactome": "R-SCE-446200", "name": "DOLPP1 dephosphorylates DOLDP to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449744", "species_29356" ], "products": [ "species_449299", "species_29372" ], "modifiers": [ [ "species_10770403", "catalyst" ] ], "additional_components": [ "YGR036C" ] }, "reaction_10762732": { "compartment": "compartment_70101", "id": "reaction_10762732", "reactome": "R-SCE-72670", "name": "Formation of eIF2:GDP:eIF2B intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762728", "species_10762689" ], "products": [ "species_10762730" ], "modifiers": [], "additional_components": [ "P09032", "YOR260W", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P32501", "YDR211W", "species_29420", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "P09032", "YOR260W", "species_29420", "P32481", "GCD11", "P09064", "SUI3", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P20459", "phospho-SUI2", "P32501", "YDR211W" ] }, "reaction_10776691": { "compartment": "compartment_7660", "id": "reaction_10776691", "reactome": "R-SCE-4616015", "name": "SUMOylation of HDAC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776117", "species_10774813" ], "products": [ "species_10776689", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "YPR068C", "P50623", "YDL064W", "Q12306", "YDR510W", "Q12306", "YDR510W", "Q12214", "YPR068C", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10785332": { "compartment": "compartment_6791047", "id": "reaction_10785332", "reactome": "R-SCE-6814831", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781520", "species_10785328" ], "products": [ "species_10785330" ], "modifiers": [], "additional_components": [ "P01123", "YFL038C", "species_29438", "YFL027C", "P01123", "YFL038C", "species_29438", "P43570", "YFL027C" ] }, "reaction_10770593": { "compartment": "compartment_70101", "id": "reaction_10770593", "reactome": "R-SCE-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29512" ], "products": [ "species_29404", "species_449701" ], "modifiers": [ [ "species_10770590", "catalyst" ] ], "additional_components": [ "P14742", "YKL104C", "P0CF18", "YMR085W" ] }, "reaction_10776528": { "compartment": "compartment_12045", "id": "reaction_10776528", "reactome": "R-SCE-4419979", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_4419981" ], "products": [ "species_29366", "species_449221" ], "modifiers": [ [ "species_10776525", "catalyst" ] ], "additional_components": [ "YIL049W" ] }, "reaction_10785861": { "compartment": "compartment_7660", "id": "reaction_10785861", "reactome": "R-SCE-8852131", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10785822", "species_10760537" ], "products": [ "species_113541", "species_10785824" ], "modifiers": [], "additional_components": [ "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10763043": { "compartment": "compartment_70101", "id": "reaction_10763043", "reactome": "R-SCE-72691", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763041", "species_10762642" ], "products": [ "species_10762644" ], "modifiers": [], "additional_components": [ "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P40217", "YMR146C", "P0CX32", "RPS24B", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C" ] }, "reaction_10776600": { "compartment": "compartment_7660", "id": "reaction_10776600", "reactome": "R-SCE-4570493", "name": "RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776590", "species_10774813" ], "products": [ "species_10776598", "species_10774805" ], "modifiers": [ [ "species_10763942", "catalyst" ] ], "additional_components": [ "YPL190C", "P50623", "YDL064W", "Q12306", "YDR510W", "P38996", "YPL190C", "Q12306", "YDR510W", "YDL064W", "P40066", "YER107C", "Q02455", "YKR095W", "P36161", "YKR082W", "P52891", "YDL116W", "P38181", "YBL079W", "P53011", "YGL100W", "P20676", "YOR098C", "P47054", "YJL039C", "Q02630", "YMR047C", "P40368", "YJL061W", "Q04491", "YLR208W", "Q05166", "YDL088C", "P46673", "YJR042W", "P48837", "YGR119C", "P34077", "YFR002W", "P14907", "YJL041W", "P52593", "YML103C", "P35729", "YKL057C", "P32500", "YML031W", "P41920", "YDR002W" ] }, "reaction_10770224": { "compartment": "compartment_1462052", "id": "reaction_10770224", "reactome": "R-SCE-437085", "name": "ZnT5 transports zinc into secretory granules in pancreatic beta cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10770221", "catalyst" ] ], "additional_components": [ "YDR205W" ] }, "reaction_10770603": { "compartment": "compartment_70101", "id": "reaction_10770603", "reactome": "R-SCE-449734", "name": "Acetylation of glucosamine 6-phosphate to GlcNAc6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449701", "species_76183" ], "products": [ "species_76194", "species_449703" ], "modifiers": [ [ "species_10770600", "catalyst" ] ], "additional_components": [ "P43577", "YFL017C" ] }, "reaction_10786570": { "compartment": "compartment_70101", "id": "reaction_10786570", "reactome": "R-SCE-8870461", "name": "RABGGTA and RABGGTB bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786564", "species_10786566" ], "products": [ "species_10786568" ], "modifiers": [], "additional_components": [ "YJL031C", "YPR176C", "P20133", "YPR176C", "Q00618", "YJL031C" ] }, "reaction_10762701": { "compartment": "compartment_70101", "id": "reaction_10762701", "reactome": "R-SCE-72669", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762640", "species_72393" ], "products": [ "species_10762642" ], "modifiers": [ [ "species_29438", "catalyst" ] ], "additional_components": [ "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438" ] }, "reaction_10781400": { "compartment": "compartment_13959", "id": "reaction_10781400", "reactome": "R-SCE-5694409", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10781393" ], "products": [ "species_10781397", "species_29420" ], "modifiers": [ [ "species_10781393", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "species_29420", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P40482", "YIL109C", "P01123", "YFL038C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C", "P25385", "YLR078C", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "species_29438", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P01123", "YFL038C", "P40482", "YIL109C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C", "P25385", "YLR078C", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "species_29420", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P40482", "YIL109C", "P01123", "YFL038C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C" ] }, "reaction_10776398": { "compartment": "compartment_7660", "id": "reaction_10776398", "reactome": "R-SCE-3968414", "name": "UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776376" ], "products": [ "species_10774805", "species_10776393" ], "modifiers": [ [ "species_10776395", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "P25364", "YCR065W", "P40466", "YIL131C", "YDL064W", "Q12306", "YDR510W", "P25364", "YCR065W", "P40466", "YIL131C", "Q04195", "YDR409W", "Q12216", "YOR156C", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10770449": { "compartment": "compartment_12045", "id": "reaction_10770449", "reactome": "R-SCE-446214", "name": "Synthesis of dolichyl-phosphate-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_449299" ], "products": [ "species_110096", "species_532214" ], "modifiers": [ [ "species_10770446", "catalyst" ] ], "additional_components": [ "YPL227C" ] }, "reaction_10785688": { "compartment": "compartment_7660", "id": "reaction_10785688", "reactome": "R-SCE-8852128", "name": "UBA1 adenylates ubiquitin in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10785583", "species_10760537" ], "products": [ "species_10785686", "species_113541" ], "modifiers": [], "additional_components": [ "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10771977": { "compartment": "compartment_20699", "id": "reaction_10771977", "reactome": "R-SCE-964825", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964831" ], "products": [ "species_964740", "species_964752" ], "modifiers": [ [ "species_10771968", "catalyst" ] ], "additional_components": [ "CHEBI:60627", "CHEBI:60629", "CHEBI:60628", "YLR057W" ] }, "reaction_10774770": { "compartment": "compartment_7660", "id": "reaction_10774770", "reactome": "R-SCE-2990840", "name": "SENP1,2,5 proteolytically process SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774758" ], "products": [ "species_10774743" ], "modifiers": [ [ "species_10774763", "catalyst" ] ], "additional_components": [ "YDR510W", "YDR510W", "YPL020C" ] }, "reaction_10776472": { "compartment": "compartment_7660", "id": "reaction_10776472", "reactome": "R-SCE-4090284", "name": "SUMOylation of HIPK2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776462" ], "products": [ "species_10776470", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YJL141C", "P14680", "YJL141C", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10782019": { "compartment": "compartment_12045", "id": "reaction_10782019", "reactome": "R-SCE-6788650", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788753", "species_71284" ], "products": [ "species_6788758", "species_71285" ], "modifiers": [ [ "species_10782016", "catalyst" ] ], "additional_components": [ "species_158417", "P32584", "YDR410C" ] }, "reaction_10785820": { "compartment": "compartment_70101", "id": "reaction_10785820", "reactome": "R-SCE-8852129", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785690", "species_10785768" ], "products": [ "species_10785818", "species_10785770" ], "modifiers": [], "additional_components": [ "P52492", "YOR339C", "P15731", "YBR082C", "P15732", "YDR059C", "P14682", "YDR054C", "P28263", "YEL012W", "Q02159", "YMR022W", "P21734", "YDR177W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52492", "YOR339C", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P28263", "YEL012W", "Q02159", "YMR022W", "P21734", "YDR177W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10770457": { "compartment": "compartment_17957", "id": "reaction_10770457", "reactome": "R-SCE-446215", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449315", "species_449229" ], "products": [ "species_449311", "species_449312" ], "modifiers": [ [ "species_10770454", "catalyst" ] ], "additional_components": [ "YNL219C" ] }, "reaction_10787521": { "compartment": "compartment_70101", "id": "reaction_10787521", "reactome": "R-SCE-8951644", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781029" ], "products": [ "species_10781027", "species_10780910" ], "modifiers": [], "additional_components": [ "P35127", "YJR099W", "Q03919", "YDR139C", "YDR139C", "YJR099W" ] }, "reaction_10770459": { "compartment": "compartment_17957", "id": "reaction_10770459", "reactome": "R-SCE-446216", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449365" ], "products": [ "species_449311", "species_449371" ], "modifiers": [ [ "species_10770454", "catalyst" ] ], "additional_components": [ "YNL219C" ] }, "reaction_10765384": { "compartment": "compartment_70101", "id": "reaction_10765384", "reactome": "R-SCE-156826", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763018" ], "products": [ "species_10765382", "species_10762778" ], "modifiers": [], "additional_components": [ "P05748", "RPL15A", "P10622", "YDL130W", "P0CX83", "RPL19B", "P26321", "RPL5", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX23", "RPL20A", "P0CX54", "RPL12B", "P51401", "RPL9B", "P14126", "RPL3", "P0CX46", "RPL2B", "P0CH08", "RPL40A", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0CX42", "RPL23B", "P53221", "RPL26B", "P10664", "RPL4A", "P05740", "RPL17A", "P0CX27", "RPL42A", "P0CX44", "RPL1B", "P0CX28", "RPL42B", "P54780", "RPL15B", "P05744", "RPL33A", "P05759", "RPS31", "P02406", "RPL28", "P0CH09", "RPL40B", "P0C0W9", "RPL11A", "P04449", "RPL24A", "P0CX50", "RPL18B", "P41805", "RPL10", "P38061", "RPL32", "P0CX49", "RPL18A", "P0CX45", "RPL2A", "P14120", "RPL30", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P0CX43", "RPL1A", "P49166", "RPL37A", "P0CX53", "RPL12A", "P05749", "RPL22A", "P0CX82", "RPL19A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q3E757", "RPL11B", "P02400", "RPP2B", "P49626", "RPL4B", "P51402", "RPL37B", "P05743", "RPL26A", "P0C2H9", "RPL31B", "P05739", "RPL6B", "P05748", "RPL15A", "P10622", "YDL130W", "P0CX83", "RPL19B", "P26321", "RPL5", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX23", "RPL20A", "P0CX54", "RPL12B", "P51401", "RPL9B", "P14126", "RPL3", "P0CX46", "RPL2B", "P0CH08", "RPL40A", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0CX42", "RPL23B", "P53221", "RPL26B", "P10664", "RPL4A", "P05740", "RPL17A", "P0CX27", "RPL42A", "P0CX44", "RPL1B", "P0CX28", "RPL42B", "P54780", "RPL15B", "P05744", "RPL33A", "P05759", "RPS31", "P02406", "RPL28", "P0CH09", "RPL40B", "P0C0W9", "RPL11A", "P04449", "RPL24A", "P0CX50", "RPL18B", "P41805", "RPL10", "P38061", "RPL32", "P0CX49", "RPL18A", "P0CX45", "RPL2A", "P14120", "RPL30", "P05737", "RPL7A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P0CX43", "RPL1A", "P49166", "RPL37A", "P0CX53", "RPL12A", "P05749", "RPL22A", "P0CX82", "RPL19A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q3E757", "RPL11B", "P02400", "RPP2B", "P49626", "RPL4B", "P51402", "RPL37B", "P05743", "RPL26A", "P0C2H9", "RPL31B", "P05739", "RPL6B" ] }, "reaction_10784442": { "compartment": "compartment_6791047", "id": "reaction_10784442", "reactome": "R-SCE-6807872", "name": "Active ARF recruits coatomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784438", "species_10784393" ], "products": [ "species_10784440" ], "modifiers": [], "additional_components": [ "P43621", "YFR051C", "P53600", "YPL010W", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P41810", "YDR238C", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P41810", "YDR238C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W" ] }, "reaction_10781493": { "compartment": "compartment_13959", "id": "reaction_10781493", "reactome": "R-SCE-5694439", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781391", "species_10781345", "species_10767942" ], "products": [ "species_10781393" ], "modifiers": [], "additional_components": [ "P38334", "YBR254C", "Q03630", "YML077W", "Q03784", "YDR246W", "P36149", "YKR068C", "Q04183", "YDR407C", "Q03337", "YDR472W", "Q03660", "YMR218C", "Q99394", "YOR115C", "species_29420", "P01123", "YFL038C", "P25385", "YLR078C", "Q01590", "YLR026C", "Q04491", "YLR208W", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "Q12204", "YOR022C", "P36015", "YKL196C", "P15303", "YPR181C", "P22214", "YLR268W", "P38968", "YDL195W", "P25385", "YLR078C", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "species_29420", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P40482", "YIL109C", "P01123", "YFL038C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C" ] }, "reaction_10763039": { "compartment": "compartment_70101", "id": "reaction_10763039", "reactome": "R-SCE-72673", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762624", "species_10763020" ], "products": [ "species_10762624", "species_10762573", "species_10763018" ], "modifiers": [], "additional_components": [ "YMR260C", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B", "YMR260C", "P0CX52", "RPS16B", "P35997", "RPS27A", "Q08745", "RPS10A", "P46784", "RPS10B", "P25443", "RPS2", "P06367", "RPS14A", "P0CX55", "RPS18A", "P0CX32", "RPS24B", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX35", "RPS4A", "P23248", "RPS1B", "P0CH08", "RPL40A", "P0CX47", "RPS11A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "P0CX37", "RPS6A", "P0CX56", "RPS18B", "P38711", "RPS27B", "P26786", "RPS7A", "P0CX30", "RPS23B", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P07281", "RPS19B", "P05759", "RPS31", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P05748", "RPL15A", "P10622", "YDL130W", "P0CX83", "RPL19B", "P26321", "RPL5", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX23", "RPL20A", "P0CX54", "RPL12B", "P51401", "RPL9B", "P14126", "RPL3", "P0CX46", "RPL2B", "P0CH08", "RPL40A", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0CX42", "RPL23B", "P53221", "RPL26B", "P10664", "RPL4A", "P05740", "RPL17A", "P0CX27", "RPL42A", "P0CX44", "RPL1B", "P0CX28", "RPL42B", "P54780", "RPL15B", "P05744", "RPL33A", "P05759", "RPS31", "P02406", "RPL28", "P0CH09", "RPL40B", "P0C0W9", "RPL11A", "P04449", "RPL24A", "P0CX50", "RPL18B", "P41805", "RPL10", "P38061", "RPL32", "P0CX49", "RPL18A", "P0CX45", "RPL2A", "P14120", "RPL30", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P0CX43", "RPL1A", "P49166", "RPL37A", "P0CX53", "RPL12A", "P05749", "RPL22A", "P0CX82", "RPL19A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q3E757", "RPL11B", "P02400", "RPP2B", "P49626", "RPL4B", "P51402", "RPL37B", "P05743", "RPL26A", "P0C2H9", "RPL31B", "P05739", "RPL6B" ] }, "reaction_10781528": { "compartment": "compartment_6791047", "id": "reaction_10781528", "reactome": "R-SCE-5694441", "name": "CSNK1D phosphorylates SEC23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10781508" ], "products": [ "species_29370", "species_10781391", "species_10781520", "species_10781512", "species_10781437", "species_10767811", "species_10781514" ], "modifiers": [ [ "species_10781525", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "P25386", "YDL058W", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "species_29438", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P01123", "YFL038C", "P40482", "YIL109C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C", "Q04410", "YDR517W", "P38334", "YBR254C", "Q03630", "YML077W", "Q03784", "YDR246W", "P36149", "YKR068C", "Q04183", "YDR407C", "Q03337", "YDR472W", "Q03660", "YMR218C", "Q99394", "YOR115C", "P01123", "YFL038C", "species_29438", "YPR181C", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "Q04491", "YLR208W", "Q12204", "YOR022C", "P38968", "YDL195W", "P25385", "YLR078C", "Q01590", "YLR026C", "P25386", "YDL058W", "P38810", "YHR098C", "P36015", "YKL196C", "P15303", "YPR181C", "P22214", "YLR268W", "Q04410", "YDR517W", "YPL204W" ] }, "reaction_10765493": { "compartment": "compartment_12045", "id": "reaction_10765493", "reactome": "R-SCE-162797", "name": "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855656", "species_449229" ], "products": [ "species_8855664" ], "modifiers": [ [ "species_10765490", "catalyst" ] ], "additional_components": [ "YOR149C" ] }, "reaction_10770398": { "compartment": "compartment_17957", "id": "reaction_10770398", "reactome": "R-SCE-446198", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449312", "species_449229" ], "products": [ "species_449311", "species_449365" ], "modifiers": [ [ "species_10770395", "catalyst" ] ], "additional_components": [ "YNR030W" ] }, "reaction_10765509": { "compartment": "compartment_12045", "id": "reaction_10765509", "reactome": "R-SCE-162821", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855667", "species_449229" ], "products": [ "species_8855656", "species_162872" ], "modifiers": [ [ "species_10765506", "catalyst" ] ], "additional_components": [ "YGL142C" ] }, "reaction_10785872": { "compartment": "compartment_7660", "id": "reaction_10785872", "reactome": "R-SCE-8852136", "name": "UBA1 conjugates ubiquitin to UBA1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785686" ], "products": [ "species_10785822", "species_164121" ], "modifiers": [], "additional_components": [ "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10781420": { "compartment": "compartment_12045", "id": "reaction_10781420", "reactome": "R-SCE-5694415", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767888", "species_10781416", "species_10767816" ], "products": [ "species_10781418" ], "modifiers": [], "additional_components": [ "YPR181C", "P53953", "YNL049C", "P40482", "YIL109C", "YLR268W", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "P22214", "YLR268W" ] }, "reaction_10787561": { "compartment": "compartment_70101", "id": "reaction_10787561", "reactome": "R-SCE-8951661", "name": "Transfer of NEDD8 to AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787550" ], "products": [ "species_10787558", "species_10787538" ], "modifiers": [ [ "species_10787550", "catalyst" ] ], "additional_components": [ "Q12059", "YPL003W", "Q99344", "YPR066W", "P52491", "YLR306W", "Q03919", "YDR139C", "P52491", "YLR306W", "Q03919", "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "P52491", "YLR306W", "Q03919", "YDR139C" ] }, "reaction_10785864": { "compartment": "compartment_70101", "id": "reaction_10785864", "reactome": "R-SCE-8852132", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785692", "species_113592", "species_10760634" ], "products": [ "species_111294", "species_10785768" ], "modifiers": [ [ "species_10785692", "catalyst" ] ], "additional_components": [ "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10762691": { "compartment": "compartment_70101", "id": "reaction_10762691", "reactome": "R-SCE-72621", "name": "Ribosomal scanning ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762680", "species_113592" ], "products": [ "species_29370", "species_10762680", "species_29372" ], "modifiers": [ [ "species_72617", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C" ] }, "reaction_10787567": { "compartment": "compartment_70101", "id": "reaction_10787567", "reactome": "R-SCE-8951751", "name": "Doubly neddylated UBA3:NAE1 binds AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787543", "species_10787548" ], "products": [ "species_10787550" ], "modifiers": [], "additional_components": [ "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C", "YLR306W", "Q12059", "YPL003W", "Q99344", "YPR066W", "P52491", "YLR306W", "Q03919", "YDR139C" ] }, "reaction_10786643": { "compartment": "compartment_70101", "id": "reaction_10786643", "reactome": "R-SCE-8870466", "name": "RGGT:CHM binds RABs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786574", "species_10786639" ], "products": [ "species_10786641" ], "modifiers": [], "additional_components": [ "species_1131164", "P32864", "YOR370C", "P20133", "YPR176C", "Q00618", "YJL031C", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "Q99260", "YLR262C", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P48559", "YNL304W", "P36017", "YOR089C", "Q99260", "YLR262C", "species_1131164", "P32864", "YOR370C", "Q00618", "YJL031C", "P36017", "YOR089C", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P20133", "YPR176C", "P48559", "YNL304W" ] }, "reaction_10776610": { "compartment": "compartment_7660", "id": "reaction_10776610", "reactome": "R-SCE-4570496", "name": "SUMOylation of Histone H4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10763701" ], "products": [ "species_10774805", "species_10776608" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YBR009C", "YDL064W", "P02309", "YBR009C", "Q12306", "YDR510W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10771137": { "compartment": "compartment_70101", "id": "reaction_10771137", "reactome": "R-SCE-532549", "name": "MPI isomerises Fru6P to Man6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_532562" ], "modifiers": [ [ "species_10771134", "catalyst" ] ], "additional_components": [ "YER003C" ] }, "reaction_10784375": { "compartment": "compartment_6791047", "id": "reaction_10784375", "reactome": "R-SCE-6807864", "name": "RAB1:GTP recruits GBF1 to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781520", "species_10784367", "species_10784371" ], "products": [ "species_10784373" ], "modifiers": [], "additional_components": [ "P01123", "YFL038C", "species_29438", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P25386", "YDL058W", "P47102", "YJR031C", "P25386", "YDL058W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "species_29438" ] }, "reaction_10785905": { "compartment": "compartment_70101", "id": "reaction_10785905", "reactome": "R-SCE-8853503", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760568" ], "products": [ "species_10762487", "species_10760568" ], "modifiers": [ [ "species_10785902", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P50101", "YMR304W", "P35127", "YJR099W" ] }, "reaction_10775006": { "compartment": "compartment_7660", "id": "reaction_10775006", "reactome": "R-SCE-3108212", "name": "SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10774426" ], "products": [ "species_10774805", "species_10774972" ], "modifiers": [ [ "species_10775003", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "P32908", "YFL008W", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "YDL064W", "P32908", "YFL008W", "Q12306", "YDR510W", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "P43124", "YDL105W", "Q12749", "YLR383W", "Q05541", "YDR288W", "P38632", "YEL019C", "Q07913", "YLR007W", "Q08204", "YOL034W" ] }, "reaction_10781488": { "compartment": "compartment_6791047", "id": "reaction_10781488", "reactome": "R-SCE-5694423", "name": "NSF and SNAPs bind cis-SNARE complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781484", "species_10769994", "species_10781444" ], "products": [ "species_10781486" ], "modifiers": [], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P22804", "YIL004C", "P22213", "YDR189W", "P36015", "YKL196C", "P32854", "YOR036W", "P22214", "YLR268W", "YBL050W", "P18759", "YBR080C", "P25385", "YLR078C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P22804", "YIL004C", "P22213", "YDR189W", "P36015", "YKL196C", "P32854", "YOR036W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W" ] }, "reaction_10765501": { "compartment": "compartment_12045", "id": "reaction_10765501", "reactome": "R-SCE-162798", "name": "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_8855659" ], "products": [ "species_8855663", "species_1500596" ], "modifiers": [ [ "species_10765498", "catalyst" ] ], "additional_components": [ "YKL165C" ] }, "reaction_10781414": { "compartment": "compartment_12045", "id": "reaction_10781414", "reactome": "R-SCE-5694413", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767882", "species_10767884", "species_10767888" ], "products": [ "species_10767890" ], "modifiers": [], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "YHR098C", "YPR181C", "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P15303", "YPR181C" ] }, "reaction_10787077": { "compartment": "compartment_70101", "id": "reaction_10787077", "reactome": "R-SCE-8932276", "name": "VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10777462" ], "products": [ "species_10787065", "species_71285" ], "modifiers": [ [ "species_10787074", "catalyst" ] ], "additional_components": [ "YDL126C", "YDL126C", "Q12367", "YLR137W", "P53970", "YNL024C" ] }, "reaction_10763037": { "compartment": "compartment_70101", "id": "reaction_10763037", "reactome": "R-SCE-72672", "name": "The 60S subunit joins the translation initiation complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762687", "species_10763027", "species_10763018" ], "products": [ "species_10763029" ], "modifiers": [], "additional_components": [ "P0CX52", "RPS16B", "P35997", "RPS27A", "Q08745", "RPS10A", "P46784", "RPS10B", "P25443", "RPS2", "P06367", "RPS14A", "P0CX55", "RPS18A", "P0CX32", "RPS24B", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX35", "RPS4A", "P23248", "RPS1B", "P0CH08", "RPL40A", "P0CX47", "RPS11A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "P0CX37", "RPS6A", "P0CX56", "RPS18B", "P38711", "RPS27B", "P26786", "RPS7A", "P0CX30", "RPS23B", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P07281", "RPS19B", "P05759", "RPS31", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "species_29438", "P39730", "YAL035W", "P05748", "RPL15A", "P10622", "YDL130W", "P0CX83", "RPL19B", "P26321", "RPL5", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX23", "RPL20A", "P0CX54", "RPL12B", "P51401", "RPL9B", "P14126", "RPL3", "P0CX46", "RPL2B", "P0CH08", "RPL40A", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0CX42", "RPL23B", "P53221", "RPL26B", "P10664", "RPL4A", "P05740", "RPL17A", "P0CX27", "RPL42A", "P0CX44", "RPL1B", "P0CX28", "RPL42B", "P54780", "RPL15B", "P05744", "RPL33A", "P05759", "RPS31", "P02406", "RPL28", "P0CH09", "RPL40B", "P0C0W9", "RPL11A", "P04449", "RPL24A", "P0CX50", "RPL18B", "P41805", "RPL10", "P38061", "RPL32", "P0CX49", "RPL18A", "P0CX45", "RPL2A", "P14120", "RPL30", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P0CX43", "RPL1A", "P49166", "RPL37A", "P0CX53", "RPL12A", "P05749", "RPL22A", "P0CX82", "RPL19A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q3E757", "RPL11B", "P02400", "RPP2B", "P49626", "RPL4B", "P51402", "RPL37B", "P05743", "RPL26A", "P0C2H9", "RPL31B", "P05739", "RPL6B", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "P39730", "YAL035W", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B" ] }, "reaction_10784389": { "compartment": "compartment_6791047", "id": "reaction_10784389", "reactome": "R-SCE-6807866", "name": "GBF1 recruits ARF:GDP to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784373", "species_10784385" ], "products": [ "species_10784387" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P25386", "YDL058W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "species_29438", "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "species_29420", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438" ] }, "reaction_10770434": { "compartment": "compartment_70101", "id": "reaction_10770434", "reactome": "R-SCE-446204", "name": "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532204", "species_29494" ], "products": [ "species_111294", "species_162756" ], "modifiers": [ [ "species_10770431", "catalyst" ] ], "additional_components": [ "P43123", "YDL103C" ] }, "reaction_10776442": { "compartment": "compartment_7660", "id": "reaction_10776442", "reactome": "R-SCE-4086083", "name": "SUMOylation of ING2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776424" ], "products": [ "species_10776440", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "Q08465", "YOR064C", "P50947", "YNL097C", "P38806", "YHR090C", "Q08465", "YOR064C", "Q12306", "YDR510W", "P50947", "YNL097C", "P38806", "YHR090C", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10787541": { "compartment": "compartment_70101", "id": "reaction_10787541", "reactome": "R-SCE-8951648", "name": "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781027", "species_113592", "species_10787528" ], "products": [ "species_111294", "species_76577", "species_10787538" ], "modifiers": [ [ "species_10787528", "catalyst" ] ], "additional_components": [ "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W" ] }, "reaction_10776669": { "compartment": "compartment_7660", "id": "reaction_10776669", "reactome": "R-SCE-4615889", "name": "SUMOylation of HDAC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772638", "species_10774813" ], "products": [ "species_10776667", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "YPR068C", "P50623", "YDL064W", "Q12306", "YDR510W", "Q12306", "YDR510W", "Q12214", "YPR068C", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10770467": { "compartment": "compartment_12045", "id": "reaction_10770467", "reactome": "R-SCE-446218", "name": "Addition of the first mannose to the N-glycan precursor by ALG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449293" ], "products": [ "species_449283", "species_29420" ], "modifiers": [ [ "species_10770464", "catalyst" ] ], "additional_components": [ "YBR110W" ] }, "reaction_10770441": { "compartment": "compartment_12045", "id": "reaction_10770441", "reactome": "R-SCE-446208", "name": "Addition of a second mannose to the N-glycan precursor by ALG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449283" ], "products": [ "species_449737", "species_29420" ], "modifiers": [ [ "species_10770438", "catalyst" ] ], "additional_components": [] }, "reaction_10784396": { "compartment": "compartment_6791047", "id": "reaction_10784396", "reactome": "R-SCE-6807868", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784387", "species_113592" ], "products": [ "species_29370", "species_10784393" ], "modifiers": [ [ "species_10784387", "catalyst" ] ], "additional_components": [ "species_29420", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "species_29420", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438" ] }, "reaction_10776681": { "compartment": "compartment_7660", "id": "reaction_10776681", "reactome": "R-SCE-4615910", "name": "SUMOylation of PCNA with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10760932" ], "products": [ "species_10774805", "species_10776679" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YBR088C", "YDL064W", "Q12306", "YDR510W", "P15873", "YBR088C", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10785219": { "compartment": "compartment_70101", "id": "reaction_10785219", "reactome": "R-SCE-6814119", "name": "TRiC/CCT binds unfolded G-protein beta subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785211", "species_10769132" ], "products": [ "species_10785217" ], "modifiers": [], "additional_components": [ "YOR212W", "P39079", "YDR188W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W" ] }, "reaction_10767954": { "compartment": "compartment_70101", "id": "reaction_10767954", "reactome": "R-SCE-203977", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10767946" ], "products": [ "species_10767870", "species_29420" ], "modifiers": [ [ "species_10767951", "catalyst" ] ], "additional_components": [ "species_29420", "P20606", "YPL218W", "P20606", "YPL218W", "species_29438", "YNR026C" ] }, "reaction_10781575": { "compartment": "compartment_70101", "id": "reaction_10781575", "reactome": "R-SCE-5694527", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767892" ], "products": [ "species_10767890", "species_10767946", "species_29372", "species_10767966" ], "modifiers": [ [ "species_10767892", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "species_29438", "P15303", "YPR181C", "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P15303", "YPR181C", "species_29420", "P20606", "YPL218W", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "species_29438", "P15303", "YPR181C" ] }, "reaction_10765418": { "compartment": "compartment_70101", "id": "reaction_10765418", "reactome": "R-SCE-156910", "name": "Formation of eEF1B complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765409", "species_10765407", "species_10765414" ], "products": [ "species_10765416" ], "modifiers": [], "additional_components": [ "YAL003W", "YAL003W", "YPL048W", "P32471", "YAL003W", "P29547", "YPL048W" ] }, "reaction_10781018": { "compartment": "compartment_70101", "id": "reaction_10781018", "reactome": "R-SCE-5690319", "name": "UCHL1, UCHL3 cleave ubiquitin adducts", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781013", "species_29356" ], "products": [ "species_1131871", "species_10781015" ], "modifiers": [ [ "species_10781013", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35127", "YJR099W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35127", "YJR099W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35127", "YJR099W" ] }, "reaction_10776553": { "compartment": "compartment_13231", "id": "reaction_10776553", "reactome": "R-SCE-4551649", "name": "RANBP2 SUMOylates RANBP2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776540" ], "products": [ "species_10774805", "species_10776550" ], "modifiers": [ [ "species_10763942", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDR002W", "YDL064W", "Q12306", "YDR510W", "P41920", "YDR002W", "P40066", "YER107C", "Q02455", "YKR095W", "P36161", "YKR082W", "P52891", "YDL116W", "P38181", "YBL079W", "P53011", "YGL100W", "P20676", "YOR098C", "P47054", "YJL039C", "Q02630", "YMR047C", "P40368", "YJL061W", "Q04491", "YLR208W", "Q05166", "YDL088C", "P46673", "YJR042W", "P48837", "YGR119C", "P34077", "YFR002W", "P14907", "YJL041W", "P52593", "YML103C", "P35729", "YKL057C", "P32500", "YML031W", "P41920", "YDR002W" ] }, "reaction_10763048": { "compartment": "compartment_70101", "id": "reaction_10763048", "reactome": "R-SCE-72722", "name": "eIF2 activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10762730" ], "products": [ "species_10762728", "species_10762640", "species_29420" ], "modifiers": [ [ "species_10762728", "catalyst" ] ], "additional_components": [ "P09032", "YOR260W", "species_29420", "P32481", "GCD11", "P09064", "SUI3", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P20459", "phospho-SUI2", "P32501", "YDR211W", "P09032", "YOR260W", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P32501", "YDR211W", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438", "P09032", "YOR260W", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P32501", "YDR211W" ] }, "reaction_10765425": { "compartment": "compartment_70101", "id": "reaction_10765425", "reactome": "R-SCE-156913", "name": "Regeneration of eEF1A:GTP by eEF1B activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10765416", "species_10765420" ], "products": [ "species_10765402", "species_10765422" ], "modifiers": [ [ "species_10765416", "catalyst" ] ], "additional_components": [ "P32471", "YAL003W", "P29547", "YPL048W", "species_29420", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "species_29438", "species_29420", "P32471", "YAL003W", "P29547", "YPL048W", "P32471", "YAL003W", "P29547", "YPL048W" ] }, "reaction_10781034": { "compartment": "compartment_70101", "id": "reaction_10781034", "reactome": "R-SCE-5690808", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781025", "species_29356" ], "products": [ "species_10781031", "species_10781029" ], "modifiers": [ [ "species_10781025", "catalyst" ] ], "additional_components": [ "P35127", "YJR099W", "Q03919", "YDR139C", "YDR139C", "P35127", "YJR099W", "Q03919", "YDR139C", "P35127", "YJR099W", "Q03919", "YDR139C" ] }, "reaction_10785911": { "compartment": "compartment_70101", "id": "reaction_10785911", "reactome": "R-SCE-8853514", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785909" ], "products": [ "species_10762930", "species_10760568" ], "modifiers": [ [ "species_10785902", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P50101", "YMR304W", "P35127", "YJR099W" ] }, "reaction_10785922": { "compartment": "compartment_70101", "id": "reaction_10785922", "reactome": "R-SCE-8853515", "name": "OTULIN,USP5 cleaves UBC yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785919" ], "products": [ "species_10760592", "species_10760600", "species_10760624", "species_10760616", "species_10760584", "species_10760576", "species_10760632", "species_10760608", "species_10760568" ], "modifiers": [ [ "species_10780500", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YBR058C" ] }, "reaction_10770390": { "compartment": "compartment_12045", "id": "reaction_10770390", "reactome": "R-SCE-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449221", "species_110614" ], "products": [ "species_449299", "species_110094" ], "modifiers": [ [ "species_10770387", "catalyst" ] ], "additional_components": [ "YMR013C" ] }, "reaction_10787545": { "compartment": "compartment_70101", "id": "reaction_10787545", "reactome": "R-SCE-8951656", "name": "NEDD8-UBA3:NAE1 binds a second NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781027", "species_113592", "species_10787538" ], "products": [ "species_10787543", "species_111294", "species_76577" ], "modifiers": [], "additional_components": [ "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C" ] }, "reaction_10781572": { "compartment": "compartment_12045", "id": "reaction_10781572", "reactome": "R-SCE-5694522", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767890", "species_10767870", "species_10767966" ], "products": [ "species_10767892" ], "modifiers": [], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P15303", "YPR181C", "P20606", "YPL218W", "species_29438", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "species_29438", "P15303", "YPR181C" ] }, "reaction_10763045": { "compartment": "compartment_70101", "id": "reaction_10763045", "reactome": "R-SCE-72697", "name": "Start codon recognition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762638", "species_10762624", "species_72617", "species_10762680", "species_10762685" ], "products": [ "species_10762638", "species_10762624", "species_72617", "species_10762680", "species_10762685" ], "modifiers": [ [ "species_72617", "catalyst" ] ], "additional_components": [ "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "YMR260C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "YPR041W", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "YMR260C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "YPR041W" ] }, "reaction_10762693": { "compartment": "compartment_70101", "id": "reaction_10762693", "reactome": "R-SCE-72631", "name": "Formation of the cap-binding eIF4F complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762672", "species_10762660", "species_10762655" ], "products": [ "species_10762674" ], "modifiers": [], "additional_components": [ "P39936", "YGL049C", "P39935", "YGR162W", "YOL139C", "P10081", "YKR059W", "P39936", "YGL049C", "P07260", "YOL139C", "P10081", "YKR059W", "P39935", "YGR162W" ] }, "reaction_10784717": { "compartment": "compartment_20699", "id": "reaction_10784717", "reactome": "R-SCE-6809014", "name": "cis-Golgi cis-SNARE binds NSF and SNAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10784713" ], "products": [ "species_10784715" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "P25385", "YLR078C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P25385", "YLR078C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W" ] }, "reaction_10774816": { "compartment": "compartment_7660", "id": "reaction_10774816", "reactome": "R-SCE-2993780", "name": "Transfer of SUMO1 from E1 to UBE2I (UBC9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774753", "species_10774805" ], "products": [ "species_10774813", "species_10774738" ], "modifiers": [ [ "species_10774738", "catalyst" ] ], "additional_components": [ "P52488", "YDR390C", "Q06624", "YPR180W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W", "P52488", "YDR390C", "Q06624", "YPR180W", "P52488", "YDR390C", "Q06624", "YPR180W" ] }, "reaction_10785335": { "compartment": "compartment_6791047", "id": "reaction_10785335", "reactome": "R-SCE-6814833", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785330" ], "products": [ "species_10785328", "species_10781345" ], "modifiers": [ [ "species_10785330", "catalyst" ] ], "additional_components": [ "P01123", "YFL038C", "species_29438", "P43570", "YFL027C", "YFL027C", "species_29420", "P01123", "YFL038C", "P01123", "YFL038C", "species_29438", "P43570", "YFL027C" ] }, "reaction_10770416": { "compartment": "compartment_70101", "id": "reaction_10770416", "reactome": "R-SCE-446201", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532562" ], "products": [ "species_532531" ], "modifiers": [ [ "species_10770411", "catalyst" ] ], "additional_components": [ "YFL045C" ] }, "reaction_10766770": { "compartment": "compartment_70101", "id": "reaction_10766770", "reactome": "R-SCE-191414", "name": "MVD decarboxylates MVA5PP to IPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191403" ], "products": [ "species_29370", "species_191362", "species_113528", "species_29372" ], "modifiers": [ [ "species_10766767", "catalyst" ] ], "additional_components": [ "P32377", "YNR043W" ] }, "reaction_10767972": { "compartment": "compartment_12045", "id": "reaction_10767972", "reactome": "R-SCE-204008", "name": "SEC31:SEC13 and v-SNARE recruitment", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767898", "species_10767824", "species_10767811" ], "products": [ "species_10767900" ], "modifiers": [], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "P48415", "YPL085W", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "species_29438", "P15303", "YPR181C", "P36015", "YKL196C", "P22214", "YLR268W", "Q04491", "YLR208W", "Q12204", "YOR022C", "P38968", "YDL195W", "P25385", "YLR078C", "P48415", "YPL085W", "P38810", "YHR098C", "P20606", "YPL218W", "species_29438", "P22214", "YLR268W", "P38968", "YDL195W", "Q01590", "YLR026C", "Q04491", "YLR208W", "P53953", "YNL049C", "P40482", "YIL109C", "Q12204", "YOR022C", "P36015", "YKL196C", "P15303", "YPR181C" ] }, "reaction_10768207": { "compartment": "compartment_876", "id": "reaction_10768207", "reactome": "R-SCE-265177", "name": "Exocyst complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768198", "species_10768183", "species_10768188", "species_10768193", "species_10768178", "species_10768173", "species_10768168", "species_10768203" ], "products": [ "species_10768205" ], "modifiers": [], "additional_components": [ "YIL068C", "YGL233W", "YBR102C", "YER008C", "YLR166C", "YDR166C", "YPR055W", "YJL085W", "P38261", "YBR102C", "P33332", "YER008C", "P89102", "YDR166C", "P32844", "YIL068C", "Q06245", "YLR166C", "P22224", "YGL233W", "P32855", "YPR055W", "P19658", "YJL085W" ] }, "reaction_10783818": { "compartment": "compartment_70101", "id": "reaction_10783818", "reactome": "R-SCE-6800138", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10783797" ], "products": [ "species_71285", "species_10783804" ], "modifiers": [ [ "species_10783815", "catalyst" ] ], "additional_components": [ "P05453", "SUP35", "P12385", "SUP45", "species_29438", "P05453", "SUP35", "P12385", "SUP45", "species_29438", "P53738", "TRM112", "Q03920", "YDR140W" ] }, "reaction_10776658": { "compartment": "compartment_7660", "id": "reaction_10776658", "reactome": "R-SCE-4615873", "name": "PIAS2-2 SUMOylates SUZ12 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776647", "species_10774813" ], "products": [ "species_10774805", "species_10776655" ], "modifiers": [ [ "species_10774918", "catalyst" ] ], "additional_components": [ "YFL049W", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "Q12306", "YDR510W", "P43554", "YFL049W", "Q04195", "YDR409W", "Q12216", "YOR156C" ] }, "reaction_10770424": { "compartment": "compartment_17957", "id": "reaction_10770424", "reactome": "R-SCE-446202", "name": "Addition of the first glucose to the N-glycan precursor by ALG6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449371", "species_532542" ], "products": [ "species_449311", "species_449649" ], "modifiers": [ [ "species_10770421", "catalyst" ] ], "additional_components": [ "YOR002W" ] }, "reaction_10776717": { "compartment": "compartment_7660", "id": "reaction_10776717", "reactome": "R-SCE-4641345", "name": "SUMOylation of TOP2B with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776708" ], "products": [ "species_10776715", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YNL088W", "P06786", "YNL088W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10776630": { "compartment": "compartment_7660", "id": "reaction_10776630", "reactome": "R-SCE-4570528", "name": "SUMOylation of XPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776620" ], "products": [ "species_10776628", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDR314C", "Q12306", "YDR510W", "Q06665", "YDR314C", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10785225": { "compartment": "compartment_70101", "id": "reaction_10785225", "reactome": "R-SCE-6814120", "name": "ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785223" ], "products": [ "species_10785217", "species_29372" ], "modifiers": [], "additional_components": [ "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_113592", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W" ] }, "reaction_10771324": { "compartment": "compartment_17957", "id": "reaction_10771324", "reactome": "R-SCE-901047", "name": "Binding of ERp57", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771171", "species_10771320" ], "products": [ "species_10771322" ], "modifiers": [], "additional_components": [ "P32474", "YDR518W", "P17967", "YCL043C", "P27825", "YAL058W", "CHEBI:59080", "P32474", "YDR518W", "P27825", "YAL058W", "CHEBI:59080", "P17967", "YCL043C" ] }, "reaction_10781764": { "compartment": "compartment_70101", "id": "reaction_10781764", "reactome": "R-SCE-6781953", "name": "YOD1 binds VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781760", "species_10777462" ], "products": [ "species_10781762" ], "modifiers": [], "additional_components": [ "YFL044C", "YDL126C", "P43558", "YFL044C", "P25694", "YDL126C" ] }, "reaction_10771979": { "compartment": "compartment_20699", "id": "reaction_10771979", "reactome": "R-SCE-964830", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964828" ], "products": [ "species_964740", "species_964752" ], "modifiers": [ [ "species_10771968", "catalyst" ] ], "additional_components": [ "YLR057W" ] }, "reaction_10787190": { "compartment": "compartment_984", "id": "reaction_10787190", "reactome": "R-SCE-8940388", "name": "GPLD1 hydrolyses GPI-anchors from proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787165", "species_109276" ], "products": [ "species_2197633", "species_10787182" ], "modifiers": [ [ "species_10787187", "catalyst" ] ], "additional_components": [ "P11491", "YDR481C", "Q07825", "YLL029W", "P11491", "YDR481C", "Q07825", "YLL029W", "YJL132W" ] }, "reaction_10777575": { "compartment": "compartment_70101", "id": "reaction_10777575", "reactome": "R-SCE-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777564", "species_71284" ], "products": [ "species_71285", "species_10777567" ], "modifiers": [ [ "species_10777572", "catalyst" ] ], "additional_components": [ "YLR172C" ] }, "reaction_10785227": { "compartment": "compartment_70101", "id": "reaction_10785227", "reactome": "R-SCE-6814124", "name": "ATP binds G-protein beta associated TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10785217" ], "products": [ "species_29370", "species_10785223" ], "modifiers": [], "additional_components": [ "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_113592", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W" ] }, "reaction_10776565": { "compartment": "compartment_7660", "id": "reaction_10776565", "reactome": "R-SCE-4568863", "name": "SUMOylation of RAD52 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10764167" ], "products": [ "species_10774805", "species_10776563" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YML032C", "YDL064W", "P06778", "YML032C", "Q12306", "YDR510W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10776732": { "compartment": "compartment_7660", "id": "reaction_10776732", "reactome": "R-SCE-4641362", "name": "SUMOylation of TOP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776722" ], "products": [ "species_10776730", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YOL006C", "P04786", "YOL006C", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10787048": { "compartment": "compartment_70101", "id": "reaction_10787048", "reactome": "R-SCE-8931974", "name": "N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10765400" ], "products": [ "species_10787040", "species_71285" ], "modifiers": [ [ "species_10787045", "catalyst" ] ], "additional_components": [ "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "YGR001C" ] }, "reaction_10765485": { "compartment": "compartment_17957", "id": "reaction_10765485", "reactome": "R-SCE-162683", "name": "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_8855661" ], "products": [ "species_76194", "species_8855666" ], "modifiers": [ [ "species_10765482", "catalyst" ] ], "additional_components": [ "YJL091C" ] }, "reaction_10785867": { "compartment": "compartment_70101", "id": "reaction_10785867", "reactome": "R-SCE-8852133", "name": "UBA1 conjugates ubiquitin to UBA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785770" ], "products": [ "species_10785692", "species_76577" ], "modifiers": [ [ "species_10785770", "catalyst" ] ], "additional_components": [ "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10768446": { "compartment": "compartment_70101", "id": "reaction_10768446", "reactome": "R-SCE-351948", "name": "Mitochondrial recruitment of Drp1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768442" ], "products": [ "species_10768444" ], "modifiers": [ [ "species_10768426", "catalyst" ] ], "additional_components": [ "YKR001C", "YKR001C", "YDL072C" ] }, "reaction_10768440": { "compartment": "compartment_13231", "id": "reaction_10768440", "reactome": "R-SCE-351947", "name": "Nuclear translocation of catalytic domain of Mst3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768434" ], "products": [ "species_10768438" ], "modifiers": [], "additional_components": [ "YHR102W", "YHR102W" ] }, "reaction_10768282": { "compartment": "compartment_7660", "id": "reaction_10768282", "reactome": "R-SCE-266204", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768278", "species_29428" ], "products": [ "species_10768280" ], "modifiers": [], "additional_components": [ "Q03435", "YDL002C", "Q02486", "YMR072W", "P33417", "YKL032C", "Q03973", "YDR174W", "P11633", "YBR089C-A", "Q03435", "YDL002C", "Q02486", "YMR072W", "P33417", "YKL032C", "Q03973", "YDR174W", "P11633", "YBR089C-A" ] }, "reaction_10786382": { "compartment": "compartment_70616", "id": "reaction_10786382", "reactome": "R-SCE-8867344", "name": "OMA1 hydrolyses OPA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_10786358" ], "products": [ "species_10786366", "species_10786374" ], "modifiers": [ [ "species_10786379", "catalyst" ] ], "additional_components": [ "P54861", "YLL001W", "P21576", "YKR001C", "P32266", "YOR211C", "P54861", "YLL001W", "P21576", "YKR001C", "P32266", "YOR211C", "P54861", "YLL001W", "P21576", "YKR001C", "P32266", "YOR211C", "YKR087C" ] }, "reaction_10761417": { "compartment": "compartment_5460", "id": "reaction_10761417", "reactome": "R-SCE-70501", "name": "Pyruvate + CO2 + ATP => ADP + Orthophosphate + Oxaloacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29376", "species_113557", "species_113593" ], "products": [ "species_113548", "species_113581", "species_113587" ], "modifiers": [ [ "species_10761414", "catalyst" ], [ "species_113559", "catalyst" ] ], "additional_components": [ "P11154", "YGL062W", "species_199207", "species_113527" ] }, "reaction_10761343": { "compartment": "compartment_70101", "id": "reaction_10761343", "reactome": "R-SCE-70482", "name": "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_29800" ], "products": [ "species_29578", "species_29360", "species_29372" ], "modifiers": [ [ "species_10761261", "catalyst" ] ], "additional_components": [ "P00360", "YJL052W", "P00358", "YJR009C", "P00359", "YGR192C" ] }, "reaction_10768527": { "compartment": "compartment_70101", "id": "reaction_10768527", "reactome": "R-SCE-372449", "name": "phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] => phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_372364", "species_76190" ], "products": [ "species_29654", "species_29492" ], "modifiers": [ [ "species_10764027", "catalyst" ] ], "additional_components": [ "YBR291C" ] }, "reaction_10761339": { "compartment": "compartment_70101", "id": "reaction_10761339", "reactome": "R-SCE-70479", "name": "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30014", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10761336", "catalyst" ], [ "species_76577", "inhibitor" ] ], "additional_components": [ "P09201", "YLR377C", "species_109496" ] }, "reaction_10762171": { "compartment": "compartment_5460", "id": "reaction_10762171", "reactome": "R-SCE-71783", "name": "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113587", "species_113529" ], "products": [ "species_113526", "species_113544" ], "modifiers": [ [ "species_10761676", "catalyst" ] ], "additional_components": [ "P17505", "YKL085W" ] }, "reaction_10761407": { "compartment": "compartment_70101", "id": "reaction_10761407", "reactome": "R-SCE-70494", "name": "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29492", "species_29356" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10761404", "catalyst" ] ], "additional_components": [ "P42222", "YMR323W", "P00924", "YGR254W", "P00925", "YHR174W", "P0CX11", "YPL281C", "P0CX10", "YOR393W", "species_109496" ] }, "reaction_10761341": { "compartment": "compartment_70101", "id": "reaction_10761341", "reactome": "R-SCE-70481", "name": "D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29578" ], "products": [ "species_75970" ], "modifiers": [ [ "species_10761271", "catalyst" ] ], "additional_components": [ "P00942", "YDR050C" ] }, "reaction_10768555": { "compartment": "compartment_70101", "id": "reaction_10768555", "reactome": "R-SCE-372843", "name": "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_113544" ], "products": [ "species_113548", "species_198498" ], "modifiers": [ [ "species_10768552", "catalyst" ] ], "additional_components": [ "YLR348C" ] }, "reaction_10761359": { "compartment": "compartment_70101", "id": "reaction_10761359", "reactome": "R-SCE-70486", "name": "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29728" ], "products": [ "species_29370", "species_29800" ], "modifiers": [ [ "species_10761356", "catalyst" ] ], "additional_components": [ "P00560", "YCR012W", "species_109496" ] }, "reaction_10788348": { "compartment": "compartment_70101", "id": "reaction_10788348", "reactome": "R-SCE-9020257", "name": "LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024893", "species_29356" ], "products": [ "species_9024879" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10788372": { "compartment": "compartment_70101", "id": "reaction_10788372", "reactome": "R-SCE-9024890", "name": "LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024873" ], "products": [ "species_9024886" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10784338": { "compartment": "compartment_70101", "id": "reaction_10784338", "reactome": "R-SCE-6807105", "name": "Monoubiquitinated PTEN translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784332" ], "products": [ "species_10784336" ], "modifiers": [], "additional_components": [ "YNL128W", "YNL128W" ] }, "reaction_10784343": { "compartment": "compartment_7660", "id": "reaction_10784343", "reactome": "R-SCE-6807118", "name": "USP7 deubiquitinates monoubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10784336" ], "products": [ "species_10784340", "species_10760537" ], "modifiers": [ [ "species_10779695", "catalyst" ] ], "additional_components": [ "YNL128W", "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YMR304W" ] }, "reaction_10784345": { "compartment": "compartment_7660", "id": "reaction_10784345", "reactome": "R-SCE-6807126", "name": "Deubiquitinated PTEN translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784340" ], "products": [ "species_10767316" ], "modifiers": [], "additional_components": [ "YNL128W", "YNL128W" ] }, "reaction_10769655": { "compartment": "compartment_876", "id": "reaction_10769655", "reactome": "R-SCE-425822", "name": "K+-independent Li+/Ca2+ exchanger transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_425815" ], "products": [ "species_425810", "species_74112" ], "modifiers": [ [ "species_10769652", "catalyst" ] ], "additional_components": [ "YJR106W" ] }, "reaction_10787919": { "compartment": "compartment_7660", "id": "reaction_10787919", "reactome": "R-SCE-9009533", "name": "TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763232", "species_10763417", "species_10787915" ], "products": [ "species_10787917" ], "modifiers": [], "additional_components": [ "P32774", "YKL058W", "P32773", "YOR194C", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P42944", "YJL110C", "P43574", "YFL021W", "P25364", "YCR065W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P18494", "YER040W", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P42944", "YJL110C", "P32774", "YKL058W", "P32773", "YOR194C", "P43574", "YFL021W", "P25364", "YCR065W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P13393", "SPT15", "P18494", "YER040W" ] }, "reaction_10787967": { "compartment": "compartment_7660", "id": "reaction_10787967", "reactome": "R-SCE-9012319", "name": "p-TEFb phosphorylates serine 2 in RNA polymerase II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10787962" ], "products": [ "species_113582", "species_10787964" ], "modifiers": [ [ "species_10787962", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "CHEBI:50114", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q05949", "YLR226W", "P34087", "YDR404C", "P22139", "RPB10", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "CHEBI:50114", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "Q05949", "YLR226W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "CHEBI:50114", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q05949", "YLR226W", "P34087", "YDR404C", "P22139", "RPB10", "P46962", "YJL006C" ] }, "reaction_10787903": { "compartment": "compartment_7660", "id": "reaction_10787903", "reactome": "R-SCE-9009065", "name": "FOXA1 and GATA3 bind to CCND1 promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787891", "species_10787885", "species_10787899" ], "products": [ "species_10772638", "species_10787901", "species_10787879" ], "modifiers": [], "additional_components": [ "P25364", "YCR065W", "P40466", "YIL131C", "P02294", "YBL002W", "P02309", "YBR009C", "Q03125", "YDR043C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "Q12214", "YPR068C", "P42944", "YJL110C", "P43574", "YFL021W", "P18494", "YER040W", "YPR068C", "P42944", "YJL110C", "P02293", "YDR224C", "P25364", "YCR065W", "P04912", "YBL003C", "P04911", "YDR225W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "Q12692", "YOL012C", "P43574", "YFL021W", "P40466", "YIL131C", "P61830", "YBR010W", "P18494", "YER040W", "YDR043C" ] }, "reaction_10787934": { "compartment": "compartment_7660", "id": "reaction_10787934", "reactome": "R-SCE-9011949", "name": "KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787929" ], "products": [ "species_10787931", "species_10776763" ], "modifiers": [ [ "species_10787929", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P39956", "YER169W", "CHEBI:50114", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "CHEBI:50114", "YER169W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P39956", "YER169W", "CHEBI:50114" ] }, "reaction_10788368": { "compartment": "compartment_7660", "id": "reaction_10788368", "reactome": "R-SCE-9023860", "name": "Histone acetyltransferases are recruited to the TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788364", "species_10788356" ], "products": [ "species_10788366" ], "modifiers": [], "additional_components": [ "P38074", "YBR034C", "P42944", "YJL110C", "P32774", "YKL058W", "P25364", "YCR065W", "P13393", "SPT15", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P32773", "YOR194C", "P43574", "YFL021W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P18494", "YER040W", "P34218", "YBL052C", "Q03330", "YGR252W", "P38074", "YBR034C", "P42944", "YJL110C", "P32774", "YKL058W", "P25364", "YCR065W", "P13393", "SPT15", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P34218", "YBL052C", "Q03330", "YGR252W", "P32773", "YOR194C", "P43574", "YFL021W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P18494", "YER040W" ] }, "reaction_10788370": { "compartment": "compartment_7660", "id": "reaction_10788370", "reactome": "R-SCE-9023861", "name": "PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787917", "species_10775032" ], "products": [ "species_10788362" ], "modifiers": [], "additional_components": [ "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P42944", "YJL110C", "P32774", "YKL058W", "P32773", "YOR194C", "P43574", "YFL021W", "P25364", "YCR065W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P13393", "SPT15", "P18494", "YER040W", "YBR034C", "P38074", "YBR034C", "P42944", "YJL110C", "P32774", "YKL058W", "P25364", "YCR065W", "P13393", "SPT15", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P32773", "YOR194C", "P43574", "YFL021W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P18494", "YER040W" ] }, "reaction_10766225": { "compartment": "compartment_13231", "id": "reaction_10766225", "reactome": "R-SCE-170825", "name": "glucokinase [nucleoplasm] => glucokinase [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766223" ], "products": [ "species_10761199" ], "modifiers": [], "additional_components": [ "Q04409", "YDR516C", "Q06204", "YLR446W", "P04806", "YFR053C", "P17709", "YCL040W", "P04807", "YGL253W", "Q04409", "YDR516C", "Q06204", "YLR446W", "P04806", "YFR053C", "P17709", "YCL040W", "P04807", "YGL253W" ] }, "reaction_10767350": { "compartment": "compartment_7660", "id": "reaction_10767350", "reactome": "R-SCE-199839", "name": "AKT can phosphorylate RSK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10767323" ], "products": [ "species_113582", "species_10767327" ], "modifiers": [ [ "species_10767347", "catalyst" ] ], "additional_components": [ "YBR028C", "YBR028C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10767701": { "compartment": "compartment_876", "id": "reaction_10767701", "reactome": "R-SCE-202692", "name": "PIP3 binds to RhoA and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765227", "species_179838" ], "products": [ "species_10767699" ], "modifiers": [], "additional_components": [ "YPR165W", "P06780", "YPR165W", "species_179838" ] }, "reaction_10788521": { "compartment": "compartment_70101", "id": "reaction_10788521", "reactome": "R-SCE-9603279", "name": "PIP3 recruits PDK1 and AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767662", "species_179838", "species_10769080" ], "products": [ "species_10788519" ], "modifiers": [], "additional_components": [ "YOL100W", "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "Q12236", "YOL100W", "P11792", "YHR205W" ] }, "reaction_10788567": { "compartment": "compartment_17947", "id": "reaction_10788567", "reactome": "R-SCE-9603775", "name": "PEX3:PEX19:class I PMP dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788555" ], "products": [ "species_10768844", "species_10788565", "species_10768864" ], "modifiers": [], "additional_components": [ "P53112", "PEX14", "P28737", "YGR028W", "P28795", "YDR329C", "Q07418", "YDL065C", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C", "YDR329C", "P53112", "PEX14", "P28737", "YGR028W", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C", "YDL065C" ] }, "reaction_10788569": { "compartment": "compartment_17947", "id": "reaction_10788569", "reactome": "R-SCE-9603784", "name": "PEX19:class I PMP binds PEX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788553", "species_10768844" ], "products": [ "species_10788555" ], "modifiers": [], "additional_components": [ "P53112", "PEX14", "P28737", "YGR028W", "Q07418", "YDL065C", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C", "YDR329C", "P53112", "PEX14", "P28737", "YGR028W", "P28795", "YDR329C", "Q07418", "YDL065C", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C" ] }, "reaction_10788571": { "compartment": "compartment_70101", "id": "reaction_10788571", "reactome": "R-SCE-9603804", "name": "PEX19 binds class I peroxisomal membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788551", "species_10768864" ], "products": [ "species_10788553" ], "modifiers": [], "additional_components": [ "P53112", "PEX14", "P28737", "YGR028W", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C", "YDL065C", "P53112", "PEX14", "P28737", "YGR028W", "Q07418", "YDL065C", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C" ] }, "reaction_10765200": { "compartment": "compartment_7660", "id": "reaction_10765200", "reactome": "R-SCE-113430", "name": "Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764338" ], "products": [ "species_10764338" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10764341": { "compartment": "compartment_7660", "id": "reaction_10764341", "reactome": "R-SCE-77071", "name": "Phosphorylation (Ser5) of RNA pol II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10764338" ], "products": [ "species_113582", "species_10764334" ], "modifiers": [ [ "species_10764338", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10764281": { "compartment": "compartment_7660", "id": "reaction_10764281", "reactome": "R-SCE-76056", "name": "Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764229", "species_10764277" ], "products": [ "species_10764279" ], "modifiers": [], "additional_components": [ "Q06339", "YDR362C", "P46678", "BDP1", "P29056", "BRF1", "P32367", "TFC1", "P33339", "TFC4", "P32805", "YGL254W", "P34111", "TFC3", "P13393", "SPT15", "P20434", "RPB5", "P32910", "RPC34", "P35718", "RPC25", "P20435", "RPO26", "P25441", "RPC53", "P07703", "RPC40", "P17890", "RPC31", "P22276", "RET1", "P20436", "RPB8", "P32349", "RPC82", "P47076", "RPC17", "P40422", "RPC10", "Q04307", "RPC11", "P22139", "RPB10", "P04051", "RPO31", "P20434", "RPB5", "Q06339", "YDR362C", "P46678", "BDP1", "P29056", "BRF1", "P32910", "RPC34", "P35718", "RPC25", "P32367", "TFC1", "P20435", "RPO26", "P25441", "RPC53", "P07703", "RPC40", "P17890", "RPC31", "P22276", "RET1", "P13393", "SPT15", "P20436", "RPB8", "P32349", "RPC82", "P47076", "RPC17", "P33339", "TFC4", "P40422", "RPC10", "Q04307", "RPC11", "P32805", "YGL254W", "P22139", "RPB10", "P04051", "RPO31", "P34111", "TFC3" ] }, "reaction_10764473": { "compartment": "compartment_7660", "id": "reaction_10764473", "reactome": "R-SCE-83805", "name": "Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764469", "species_10764277" ], "products": [ "species_10764471" ], "modifiers": [], "additional_components": [ "Q06339", "YDR362C", "P46678", "BDP1", "P29056", "BRF1", "P32367", "TFC1", "P33339", "TFC4", "P34111", "TFC3", "P13393", "SPT15", "P20434", "RPB5", "P32910", "RPC34", "P35718", "RPC25", "P20435", "RPO26", "P25441", "RPC53", "P07703", "RPC40", "P17890", "RPC31", "P22276", "RET1", "P20436", "RPB8", "P32349", "RPC82", "P47076", "RPC17", "P40422", "RPC10", "Q04307", "RPC11", "P22139", "RPB10", "P04051", "RPO31", "P20434", "RPB5", "Q06339", "YDR362C", "P46678", "BDP1", "P29056", "BRF1", "P32910", "RPC34", "P35718", "RPC25", "P32367", "TFC1", "P20435", "RPO26", "P25441", "RPC53", "P07703", "RPC40", "P17890", "RPC31", "P22276", "RET1", "P13393", "SPT15", "P20436", "RPB8", "P32349", "RPC82", "P47076", "RPC17", "P33339", "TFC4", "P40422", "RPC10", "Q04307", "RPC11", "P22139", "RPB10", "P04051", "RPO31", "P34111", "TFC3" ] }, "reaction_10764192": { "compartment": "compartment_7660", "id": "reaction_10764192", "reactome": "R-SCE-76052", "name": "Binding of TFIIIA To type 1 Promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76050", "species_10764188" ], "products": [ "species_10764190" ], "modifiers": [], "additional_components": [ "YGL254W", "P32805", "YGL254W" ] }, "reaction_10765180": { "compartment": "compartment_7660", "id": "reaction_10765180", "reactome": "R-SCE-112396", "name": "Separation of elongating transcript from template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765176" ], "products": [ "species_10765178" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765194": { "compartment": "compartment_7660", "id": "reaction_10765194", "reactome": "R-SCE-113412", "name": "Pol II elongation complex moves on the template as transcript elongates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10765164" ], "products": [ "species_9757634", "species_10765176" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765188": { "compartment": "compartment_7660", "id": "reaction_10765188", "reactome": "R-SCE-113407", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764987", "species_10764978" ], "products": [ "species_10764989" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10", "P27692", "YML010W", "P32914", "YGR063C", "P41896", "YGR005C", "P20434", "RPB5", "P27692", "YML010W", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P32914", "YGR063C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10765166": { "compartment": "compartment_7660", "id": "reaction_10765166", "reactome": "R-SCE-112385", "name": "Addition of nucleotides leads to transcript elongation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10765162" ], "products": [ "species_10763293", "species_10765164" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53861", "YNL230C", "P53930", "YNL107W", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P06839", "RAD3", "P46962", "YJL006C", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765033": { "compartment": "compartment_7660", "id": "reaction_10765033", "reactome": "R-SCE-112383", "name": "Hypophosphorylation of RNA Pol II CTD by FCP1P protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762306", "species_10763293", "species_10764985" ], "products": [ "species_10764987", "species_10763293" ], "modifiers": [ [ "species_10764985", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "YMR277W", "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "YMR277W" ] }, "reaction_10788729": { "compartment": "compartment_876", "id": "reaction_10788729", "reactome": "R-SCE-9632858", "name": "PRKCZ autophosphorylates downstream of estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10788721" ], "products": [ "species_29370", "species_10788726" ], "modifiers": [ [ "species_10788721", "catalyst" ] ], "additional_components": [ "P24583", "YBL105C", "species_179838", "Q12236", "YOL100W", "P24583", "YBL105C", "species_179838", "Q12236", "YOL100W", "P24583", "YBL105C", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10788731": { "compartment": "compartment_7660", "id": "reaction_10788731", "reactome": "R-SCE-9632910", "name": "ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775860" ], "products": [ "species_10767242" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "P16892", "YBL016W" ] }, "reaction_10788690": { "compartment": "compartment_876", "id": "reaction_10788690", "reactome": "R-SCE-9625814", "name": "SPHK1 phosphorylates sphingosine in response to E2 stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1606609" ], "products": [ "species_5218688" ], "modifiers": [ [ "species_10769088", "catalyst" ] ], "additional_components": [ "YLR260W" ] }, "reaction_10786822": { "compartment": "compartment_70101", "id": "reaction_10786822", "reactome": "R-SCE-8875623", "name": "SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29404" ], "products": [ "species_113552", "species_113529" ], "modifiers": [ [ "species_10786819", "catalyst" ] ], "additional_components": [ "Q99297", "YOR222W", "Q03028", "YPL134C" ] }, "reaction_10775307": { "compartment": "compartment_20699", "id": "reaction_10775307", "reactome": "R-SCE-3247836", "name": "Retromer recycles WLS to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775301" ], "products": [ "species_10775305" ], "modifiers": [], "additional_components": [ "Q08826", "YOR357C", "P38759", "YHR012W", "P40335", "YJL053W", "P34110", "YJL154C", "Q08826", "YOR357C", "P38759", "YHR012W", "P40335", "YJL053W", "P34110", "YJL154C" ] }, "reaction_10768807": { "compartment": "compartment_70101", "id": "reaction_10768807", "reactome": "R-SCE-381727", "name": "RAP1A exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768805", "species_29438" ], "products": [ "species_10768481", "species_29420" ], "modifiers": [], "additional_components": [ "species_111349", "P13856", "YGR152C", "species_29438", "P13856", "YGR152C" ] }, "reaction_10781313": { "compartment": "compartment_5460", "id": "reaction_10781313", "reactome": "R-SCE-5694018", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781300", "species_113526" ], "products": [ "species_10781283", "species_29362", "species_113529" ], "modifiers": [ [ "species_10781310", "catalyst" ] ], "additional_components": [ "CHEBI:50746", "P39726", "YAL044C", "YAL044C", "P09624", "YFL018C", "species_113596" ] }, "reaction_10781298": { "compartment": "compartment_5460", "id": "reaction_10781298", "reactome": "R-SCE-5693967", "name": "PXLP-K754-GLDC dimer decarboxylates Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781283", "species_159549" ], "products": [ "species_29376", "species_10781287" ], "modifiers": [ [ "species_10781295", "catalyst" ] ], "additional_components": [ "YAL044C", "CHEBI:14949", "P39726", "YAL044C", "P49095", "YMR189W" ] }, "reaction_10781308": { "compartment": "compartment_5460", "id": "reaction_10781308", "reactome": "R-SCE-5693977", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_10781287" ], "products": [ "species_5693984", "species_10781300", "species_5693978" ], "modifiers": [ [ "species_10781305", "catalyst" ] ], "additional_components": [ "CHEBI:14949", "P39726", "YAL044C", "CHEBI:50746", "P39726", "YAL044C", "YDR019C" ] }, "reaction_10769352": { "compartment": "compartment_876", "id": "reaction_10769352", "reactome": "R-SCE-418582", "name": "G alpha (q) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764870" ], "products": [ "species_10769349" ], "modifiers": [ [ "species_10764870", "catalyst" ] ], "additional_components": [ "species_29438", "P10823", "YER020W", "species_111349", "P10823", "YER020W", "species_29438", "P10823", "YER020W" ] }, "reaction_10765298": { "compartment": "compartment_876", "id": "reaction_10765298", "reactome": "R-SCE-114688", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765293" ], "products": [ "species_10765295" ], "modifiers": [ [ "species_10764872", "catalyst" ] ], "additional_components": [ "P32383", "YPL268W", "species_29438", "species_179856", "P10823", "YER020W", "species_114520", "P32383", "YPL268W", "species_6797635", "species_29438", "P10823", "YER020W", "P32383", "YPL268W", "species_29438", "P10823", "YER020W" ] }, "reaction_10769199": { "compartment": "compartment_876", "id": "reaction_10769199", "reactome": "R-SCE-400015", "name": "Diacylgycerol activates Protein kinase C, alpha type", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765240", "species_114519" ], "products": [ "species_10769197" ], "modifiers": [], "additional_components": [ "YBL105C", "P24583", "YBL105C", "species_6797635" ] }, "reaction_10787442": { "compartment": "compartment_70101", "id": "reaction_10787442", "reactome": "R-SCE-8948039", "name": "FUNDC1 is phosphorylated by CK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787437", "species_113592" ], "products": [ "species_29370", "species_10787440" ], "modifiers": [ [ "species_10774577", "catalyst" ] ], "additional_components": [ "YAL008W", "YAL008W", "P15790", "CKA1", "P38930", "CKB2", "P19454", "CKA2" ] }, "reaction_10787455": { "compartment": "compartment_17906", "id": "reaction_10787455", "reactome": "R-SCE-8948146", "name": "FUNDC1 is phosphorylated by ULK1 at Ser17", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787437", "species_113592" ], "products": [ "species_29370", "species_10787452" ], "modifiers": [ [ "species_10787444", "catalyst" ] ], "additional_components": [ "YAL008W", "YAL008W", "YGL180W" ] }, "reaction_10787722": { "compartment": "compartment_21994", "id": "reaction_10787722", "reactome": "R-SCE-8959571", "name": "LC3 binds the autophagosome membrane Atg5-Atg12 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787718", "species_10777022" ], "products": [ "species_10787720" ], "modifiers": [], "additional_components": [ "P18411", "YAL008W", "P38182", "YBL078C", "Q12380", "YPL149W", "P38316", "YBR217W", "Q12380", "YPL149W", "P18411", "YAL008W", "P38316", "YBR217W", "P38182", "YBL078C" ] }, "reaction_10787446": { "compartment": "compartment_17906", "id": "reaction_10787446", "reactome": "R-SCE-8948136", "name": "ULK1 Translocates to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778616" ], "products": [ "species_10787444" ], "modifiers": [], "additional_components": [ "YGL180W", "YGL180W" ] }, "reaction_10787724": { "compartment": "compartment_70101", "id": "reaction_10787724", "reactome": "R-SCE-8959573", "name": "Phosphorylated FUNDC1 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779041", "species_10787452" ], "products": [ "species_10787718" ], "modifiers": [], "additional_components": [ "YBL078C", "YAL008W", "P18411", "YAL008W", "P38182", "YBL078C" ] }, "reaction_10788643": { "compartment": "compartment_70101", "id": "reaction_10788643", "reactome": "R-SCE-9617595", "name": "SGTA binds mislocalized membrane protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788608", "species_10788577" ], "products": [ "species_10788641" ], "modifiers": [], "additional_components": [ "P33328", "YOR327C", "P31109", "YAL030W", "Q12118", "SGT2", "P33328", "YOR327C", "Q12118", "SGT2", "P31109", "YAL030W" ] }, "reaction_10788616": { "compartment": "compartment_70101", "id": "reaction_10788616", "reactome": "R-SCE-9609921", "name": "SGTA binds Tail-anchored protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788612", "species_10788577" ], "products": [ "species_10788614" ], "modifiers": [], "additional_components": [ "Q01590", "YLR026C", "P33296", "YER100W", "P35179", "YDR086C", "P52871", "YER019C-A", "P32867", "YPL232W", "P33328", "YOR327C", "Q04458", "YMR110C", "P40075", "YER120W", "P38374", "YBR162W-A", "P31109", "YAL030W", "P40312", "YNL111C", "P39926", "YMR183C", "Q12118", "SGT2", "Q01590", "YLR026C", "P33296", "YER100W", "P35179", "YDR086C", "P52871", "YER019C-A", "P32867", "YPL232W", "P33328", "YOR327C", "Q04458", "YMR110C", "P40075", "YER120W", "P38374", "YBR162W-A", "Q12118", "SGT2", "P31109", "YAL030W", "P40312", "YNL111C", "P39926", "YMR183C" ] }, "reaction_10773413": { "compartment": "compartment_876", "id": "reaction_10773413", "reactome": "R-SCE-1640164", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429776", "species_29356" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10773410", "catalyst" ] ], "additional_components": [ "P39997", "YEL016C", "P25353", "YCR026C" ] }, "reaction_10773363": { "compartment": "compartment_876", "id": "reaction_10773363", "reactome": "R-SCE-1606273", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429776", "species_29356" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10773360", "catalyst" ] ], "additional_components": [ "P40015", "YER019W", "species_109496" ] }, "reaction_10785153": { "compartment": "compartment_7660", "id": "reaction_10785153", "reactome": "R-SCE-6811522", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_6810408" ], "products": [ "species_113582", "species_6810412" ], "modifiers": [ [ "species_10785150", "catalyst" ] ], "additional_components": [ "P38994", "YDR208W" ] }, "reaction_10768746": { "compartment": "compartment_5460", "id": "reaction_10768746", "reactome": "R-SCE-380608", "name": "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380598", "species_113526" ], "products": [ "species_380593", "species_29362", "species_113529" ], "modifiers": [ [ "species_10762134", "catalyst" ] ], "additional_components": [ "P40047", "YER073W" ] }, "reaction_10766908": { "compartment": "compartment_70101", "id": "reaction_10766908", "reactome": "R-SCE-194678", "name": "CYP51A1 demethylates LNSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194634", "species_29368" ], "products": [ "species_29366", "species_194644", "species_29460", "species_29356" ], "modifiers": [ [ "species_10766905", "catalyst" ] ], "additional_components": [ "YHR007C" ] }, "reaction_10776925": { "compartment": "compartment_7660", "id": "reaction_10776925", "reactome": "R-SCE-5082384", "name": "HSP70:DNAJB1 binds HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775782", "species_10775812" ], "products": [ "species_10775814" ], "modifiers": [], "additional_components": [ "P36016", "YKL073W", "P25294", "YNL007C", "P22202", "YER103W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P38889", "YHR206W", "P10961", "YGL073W", "P36016", "YKL073W", "P25294", "YNL007C", "P22202", "YER103W", "P38889", "YHR206W", "P09435", "YBL075C", "P10592", "YLL024C", "P10961", "YGL073W", "P10591", "YAL005C" ] }, "reaction_10788335": { "compartment": "compartment_70101", "id": "reaction_10788335", "reactome": "R-SCE-9018824", "name": "RHOT2 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788331", "species_10788314" ], "products": [ "species_10788333" ], "modifiers": [], "additional_components": [ "P32492", "YAL029C", "P38297", "YBR179C", "P19524", "YOR326W", "species_29438", "P39722", "YAL048C", "P32492", "YAL029C", "P38297", "YBR179C", "species_29438", "P19524", "YOR326W", "P39722", "YAL048C" ] }, "reaction_10788319": { "compartment": "compartment_70101", "id": "reaction_10788319", "reactome": "R-SCE-9018814", "name": "RHOT1 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788314", "species_29356" ], "products": [ "species_10788316", "species_29372" ], "modifiers": [ [ "species_10788314", "catalyst" ] ], "additional_components": [ "species_29438", "P39722", "YAL048C", "species_29420", "P39722", "YAL048C", "species_29438", "P39722", "YAL048C" ] }, "reaction_10788329": { "compartment": "compartment_17906", "id": "reaction_10788329", "reactome": "R-SCE-9018815", "name": "RHOT1 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788325", "species_10788314" ], "products": [ "species_10788327" ], "modifiers": [], "additional_components": [ "P32492", "YAL029C", "P19524", "YOR326W", "species_29438", "P39722", "YAL048C", "P32492", "YAL029C", "species_29438", "P19524", "YOR326W", "P39722", "YAL048C" ] }, "reaction_10788337": { "compartment": "compartment_70101", "id": "reaction_10788337", "reactome": "R-SCE-9018826", "name": "RHOT2 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788314", "species_29356" ], "products": [ "species_10788316", "species_29372" ], "modifiers": [ [ "species_10788314", "catalyst" ] ], "additional_components": [ "species_29438", "P39722", "YAL048C", "species_29420", "P39722", "YAL048C", "species_29438", "P39722", "YAL048C" ] }, "reaction_10769669": { "compartment": "compartment_172574", "id": "reaction_10769669", "reactome": "R-SCE-425965", "name": "SLC9A9 exchanges Na+ for H+ across the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_83910", "species_425999" ], "products": [ "species_70106", "species_425977" ], "modifiers": [ [ "species_10769666", "catalyst" ] ], "additional_components": [ "YDR456W" ] }, "reaction_10769676": { "compartment": "compartment_171062", "id": "reaction_10769676", "reactome": "R-SCE-425983", "name": "SLC9A6,7 exchange Na+ for H+ across the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425978", "species_83910" ], "products": [ "species_70106", "species_425971" ], "modifiers": [ [ "species_10769671", "catalyst" ] ], "additional_components": [ "YDR456W" ] }, "reaction_10769681": { "compartment": "compartment_20699", "id": "reaction_10769681", "reactome": "R-SCE-426015", "name": "Na+/H+ exchanger transport (at trans-golgi membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425969", "species_83910" ], "products": [ "species_70106", "species_425958" ], "modifiers": [ [ "species_10769678", "catalyst" ] ], "additional_components": [ "YDR456W" ] }, "reaction_10766728": { "compartment": "compartment_70101", "id": "reaction_10766728", "reactome": "R-SCE-191366", "name": "Squalene 2,3-epoxide cyclizes, forming lanosterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191309" ], "products": [ "species_194634" ], "modifiers": [ [ "species_10766725", "catalyst" ] ], "additional_components": [ "YHR072W" ] }, "reaction_10787021": { "compartment": "compartment_5460", "id": "reaction_10787021", "reactome": "R-SCE-8878815", "name": "Formation of 4Fe-4S cluster on ISCA1:ISCA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787001", "species_10787013" ], "products": [ "species_10786999", "species_10787015" ], "modifiers": [ [ "species_10787019", "catalyst" ] ], "additional_components": [ "CHEBI:33739", "Q02784", "YPL059W", "Q12425", "YPR067W", "Q07821", "YLL027W", "YPL059W", "Q12425", "YPR067W", "CHEBI:49883", "Q07821", "YLL027W" ] }, "reaction_10789204": { "compartment": "compartment_70101", "id": "reaction_10789204", "reactome": "R-SCE-9705714", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_29366", "species_469662" ], "modifiers": [ [ "species_10776525", "catalyst" ] ], "additional_components": [ "YIL049W" ] }, "reaction_10785545": { "compartment": "compartment_984", "id": "reaction_10785545", "reactome": "R-SCE-8851129", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8870906", "species_109276" ], "products": [ "species_8870962", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785539", "catalyst" ] ], "additional_components": [ "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10781870": { "compartment": "compartment_70101", "id": "reaction_10781870", "reactome": "R-SCE-6783221", "name": "HAGH hydrolyses (R)-S-LGSH to GSH and LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694130" ], "products": [ "species_29450", "species_29708" ], "modifiers": [ [ "species_10781867", "catalyst" ] ], "additional_components": [ "species_158417", "Q12320", "YOR040W" ] }, "reaction_10767283": { "compartment": "compartment_70101", "id": "reaction_10767283", "reactome": "R-SCE-198845", "name": "CYB5A:heme reduces Asc.- to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767269", "species_1497805" ], "products": [ "species_10767267", "species_198816" ], "modifiers": [ [ "species_10767269", "catalyst" ] ], "additional_components": [ "species_189444", "P40312", "YNL111C", "CHEBI:36144", "P40312", "YNL111C", "species_189444", "P40312", "YNL111C" ] }, "reaction_10771989": { "compartment": "compartment_70101", "id": "reaction_10771989", "reactome": "R-SCE-964958", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964945", "species_113592" ], "products": [ "species_29370", "species_965146" ], "modifiers": [ [ "species_10771986", "catalyst" ] ], "additional_components": [ "species_158417", "P39988", "YEL029C" ] }, "reaction_10769063": { "compartment": "compartment_17951", "id": "reaction_10769063", "reactome": "R-SCE-390291", "name": "acetyl-CoA + carnitine => acetylcarnitine + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390294", "species_353123" ], "products": [ "species_193514", "species_390287" ], "modifiers": [ [ "species_10769058", "catalyst" ] ], "additional_components": [ "YML042W" ] }, "reaction_10773576": { "compartment": "compartment_12045", "id": "reaction_10773576", "reactome": "R-SCE-1676124", "name": "PI4P is dephosphorylated to PI by SACM1L at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806234", "species_29356" ], "products": [ "species_426639", "species_29372" ], "modifiers": [ [ "species_10773573", "catalyst" ] ], "additional_components": [ "YKL212W" ] }, "reaction_10771313": { "compartment": "compartment_70101", "id": "reaction_10771313", "reactome": "R-SCE-893596", "name": "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398", "species_29970" ], "products": [ "species_893615", "species_29432" ], "modifiers": [ [ "species_10771307", "catalyst" ], [ "species_8939576", "inhibitor" ], [ "species_29502", "inhibitor" ] ], "additional_components": [ "P47039", "YJL060W", "CHEBI:55528", "CHEBI:43580" ] }, "reaction_10778606": { "compartment": "compartment_70101", "id": "reaction_10778606", "reactome": "R-SCE-5662466", "name": "XYLB phosphorylates D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5661281", "species_113592" ], "products": [ "species_29370", "species_29790" ], "modifiers": [ [ "species_10778603", "catalyst" ] ], "additional_components": [ "YGR194C" ] }, "reaction_10763390": { "compartment": "compartment_70101", "id": "reaction_10763390", "reactome": "R-SCE-73813", "name": "GAR + 10-Formyl-THF => FGAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111338", "species_419151" ], "products": [ "species_70106", "species_111354", "species_111355" ], "modifiers": [ [ "species_10763376", "catalyst" ] ], "additional_components": [ "YGL234W" ] }, "reaction_10784783": { "compartment": "compartment_17951", "id": "reaction_10784783", "reactome": "R-SCE-6809808", "name": "ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6809801" ], "products": [ "species_6809800" ], "modifiers": [ [ "species_10784780", "catalyst" ] ], "additional_components": [ "P31787", "YGR037C" ] }, "reaction_10774954": { "compartment": "compartment_70101", "id": "reaction_10774954", "reactome": "R-SCE-3095901", "name": "ABCC1 transports cytosolic Cbl to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3000241", "species_29356" ], "products": [ "species_29370", "species_3000125", "species_29372" ], "modifiers": [ [ "species_10768249", "catalyst" ] ], "additional_components": [ "YDR135C" ] }, "reaction_10781339": { "compartment": "compartment_70616", "id": "reaction_10781339", "reactome": "R-SCE-5694137", "name": "PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693984", "species_113521", "species_159549" ], "products": [ "species_200671", "species_379732" ], "modifiers": [ [ "species_10781336", "catalyst" ] ], "additional_components": [ "P37291", "YLR058C", "P37292", "YBR263W" ] }, "reaction_10762043": { "compartment": "compartment_70101", "id": "reaction_10762043", "reactome": "R-SCE-71593", "name": "((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761992" ], "products": [ "species_70113", "species_10762040" ], "modifiers": [ [ "species_10761997", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_113527", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_113527", "P36143", "YKR058W", "YPR184W" ] }, "reaction_10769898": { "compartment": "compartment_70101", "id": "reaction_10769898", "reactome": "R-SCE-428676", "name": "sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203" ], "products": [ "species_428686", "species_428671" ], "modifiers": [ [ "species_10769895", "catalyst" ] ], "additional_components": [ "YDR294C" ] }, "reaction_10787703": { "compartment": "compartment_70101", "id": "reaction_10787703", "reactome": "R-SCE-8955844", "name": "RBKS phosphorylates ribose to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8955853" ], "products": [ "species_29370", "species_73578" ], "modifiers": [ [ "species_10787700", "catalyst" ] ], "additional_components": [ "YCR036W" ] }, "reaction_10773027": { "compartment": "compartment_12045", "id": "reaction_10773027", "reactome": "R-SCE-1482612", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10773044": { "compartment": "compartment_70101", "id": "reaction_10773044", "reactome": "R-SCE-1482656", "name": "PA is hydrolysed to 1-acyl LPA by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_1500604", "species_1524021" ], "modifiers": [ [ "species_10772999", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10766748": { "compartment": "compartment_70101", "id": "reaction_10766748", "reactome": "R-SCE-191382", "name": "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362" ], "products": [ "species_191324" ], "modifiers": [ [ "species_10766745", "catalyst" ] ], "additional_components": [ "P15496", "YPL117C", "species_109496" ] }, "reaction_10773106": { "compartment": "compartment_70616", "id": "reaction_10773106", "reactome": "R-SCE-1482759", "name": "MLCL is hydrolyzed to DLCL by PLA2G4A (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498773", "species_113521" ], "products": [ "species_1524085", "species_1498753" ], "modifiers": [ [ "species_10773103", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10784748": { "compartment": "compartment_876", "id": "reaction_10784748", "reactome": "R-SCE-6809325", "name": "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10784742", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10761813": { "compartment": "compartment_70101", "id": "reaction_10761813", "reactome": "R-SCE-71249", "name": "SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31503" ], "products": [ "species_29424", "species_31311" ], "modifiers": [ [ "species_10761810", "catalyst" ] ], "additional_components": [ "P37292", "YBR263W" ] }, "reaction_10785576": { "compartment": "compartment_528865", "id": "reaction_10785576", "reactome": "R-SCE-8851494", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851509", "species_8851517" ], "products": [ "species_8851518", "species_8851513", "species_5228597" ], "modifiers": [ [ "species_10785573", "catalyst" ] ], "additional_components": [ "species_29494", "species_29438", "species_110614", "species_29420", "species_110096", "species_110094", "P40009", "YER005W", "species_74016" ] }, "reaction_10767509": { "compartment": "compartment_70101", "id": "reaction_10767509", "reactome": "R-SCE-200676", "name": "MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200739" ], "products": [ "species_29366", "species_174404" ], "modifiers": [ [ "species_10767506", "catalyst" ] ], "additional_components": [ "P53128", "YGL125W" ] }, "reaction_10773109": { "compartment": "compartment_12045", "id": "reaction_10773109", "reactome": "R-SCE-1482771", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[9]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_29356" ], "products": [ "species_1498724", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10761833": { "compartment": "compartment_70101", "id": "reaction_10761833", "reactome": "R-SCE-71286", "name": "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_30401" ], "products": [ "species_70106", "species_71285", "species_29916" ], "modifiers": [ [ "species_10761830", "catalyst" ] ], "additional_components": [ "YDR465C" ] }, "reaction_10766996": { "compartment": "compartment_70101", "id": "reaction_10766996", "reactome": "R-SCE-196955", "name": "2xENPP1 hydrolyzes FAD to FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29386", "species_29356" ], "products": [ "species_73524", "species_76577" ], "modifiers": [ [ "species_10766993", "catalyst" ] ], "additional_components": [ "P39997", "YEL016C", "P25353", "YCR026C" ] }, "reaction_10775588": { "compartment": "compartment_70101", "id": "reaction_10775588", "reactome": "R-SCE-3322016", "name": "GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775576" ], "products": [ "species_10775586" ], "modifiers": [ [ "species_10775557", "catalyst" ] ], "additional_components": [ "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "YEL011W" ] }, "reaction_10766523": { "compartment": "compartment_70101", "id": "reaction_10766523", "reactome": "R-SCE-189406", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189464", "species_29356" ], "products": [ "species_189449", "species_31633" ], "modifiers": [ [ "species_10766520", "catalyst" ] ], "additional_components": [ "CHEBI:36319", "P28789", "YDL205C" ] }, "reaction_10775584": { "compartment": "compartment_70101", "id": "reaction_10775584", "reactome": "R-SCE-3322014", "name": "Autoglucosylation of GYG2 complexed with GYS2-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775581" ], "products": [ "species_110096", "species_10775574" ], "modifiers": [ [ "species_10775581", "catalyst" ] ], "additional_components": [ "P27472", "YLR258W", "P47011", "YJL137C", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P27472", "YLR258W", "P47011", "YJL137C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10767006": { "compartment": "compartment_70101", "id": "reaction_10767006", "reactome": "R-SCE-196964", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196931" ], "products": [ "species_29370", "species_73524" ], "modifiers": [ [ "species_10767003", "catalyst" ] ], "additional_components": [ "Q03778", "YDR236C", "species_109496" ] }, "reaction_10773229": { "compartment": "compartment_12045", "id": "reaction_10773229", "reactome": "R-SCE-1482976", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426955", "species_426910" ], "products": [ "species_109395", "species_426639" ], "modifiers": [ [ "species_10773226", "catalyst" ] ], "additional_components": [ "P06197", "YPR113W", "species_113527", "species_109496" ] }, "reaction_10787576": { "compartment": "compartment_984", "id": "reaction_10787576", "reactome": "R-SCE-8952251", "name": "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2173763", "species_109276" ], "products": [ "species_8952253", "species_8954142" ], "modifiers": [ [ "species_10787573", "catalyst" ] ], "additional_components": [ "YDR058C" ] }, "reaction_10761616": { "compartment": "compartment_5460", "id": "reaction_10761616", "reactome": "R-SCE-70724", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_508190" ], "products": [ "species_113552", "species_508181" ], "modifiers": [ [ "species_10761613", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "species_351964", "CHEBI:57762", "CHEBI:28654", "CHEBI:16530", "CHEBI:17865", "P47176", "YJR148W", "P38891", "YHR208W" ] }, "reaction_10778320": { "compartment": "compartment_70101", "id": "reaction_10778320", "reactome": "R-SCE-5652195", "name": "SORD oxidizes D-sorbitol to Fru", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_5652213" ], "products": [ "species_70106", "species_73473", "species_29532" ], "modifiers": [ [ "species_10778317", "catalyst" ] ], "additional_components": [ "Q07993", "YLR070C", "species_158417", "Q07786", "YDL246C", "P35497", "YJR159W" ] }, "reaction_10763347": { "compartment": "compartment_70101", "id": "reaction_10763347", "reactome": "R-SCE-73794", "name": "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29602", "species_29360", "species_29356" ], "products": [ "species_73473", "species_70106", "species_111584" ], "modifiers": [ [ "species_10763342", "catalyst" ], [ "species_10763345", "inhibitor" ], [ "species_111584", "inhibitor" ] ], "additional_components": [ "P38697", "YHR216W", "P50095", "YLR432W", "P50094", "YML056C", "P38697", "YHR216W", "P50095", "YLR432W", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842", "P50094", "YML056C" ] }, "reaction_10788488": { "compartment": "compartment_70101", "id": "reaction_10788488", "reactome": "R-SCE-9034539", "name": "PXLP-K56-SRR dimer deaminates L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_29382", "species_29398", "species_29356" ], "modifiers": [ [ "species_10788216", "catalyst" ] ], "additional_components": [ "P36007", "YKL218C" ] }, "reaction_10784328": { "compartment": "compartment_12045", "id": "reaction_10784328", "reactome": "R-SCE-6807053", "name": "SC5D desaturates LTHSOL to 7-dehydroCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_6807054", "species_29368" ], "products": [ "species_29366", "species_6807057", "species_29356" ], "modifiers": [ [ "species_10766920", "catalyst" ] ], "additional_components": [ "YLR056W" ] }, "reaction_10773042": { "compartment": "compartment_12045", "id": "reaction_10773042", "reactome": "R-SCE-1482646", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10773037", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10764110": { "compartment": "compartment_12045", "id": "reaction_10764110", "reactome": "R-SCE-75885", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500604", "species_1500578" ], "products": [ "species_76194", "species_426755" ], "modifiers": [ [ "species_10764107", "catalyst" ] ], "additional_components": [ "P33333", "YDL052C", "Q08750", "YOR298W", "P38226", "YBR042C" ] }, "reaction_10769889": { "compartment": "compartment_70101", "id": "reaction_10769889", "reactome": "R-SCE-428664", "name": "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428275", "species_29356" ], "products": [ "species_428694", "species_29372" ], "modifiers": [ [ "species_10769886", "catalyst" ] ], "additional_components": [ "P47013", "YJL134W", "P23501", "YKR053C" ] }, "reaction_10766913": { "compartment": "compartment_70101", "id": "reaction_10766913", "reactome": "R-SCE-194698", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194644" ], "products": [ "species_29366", "species_194633" ], "modifiers": [ [ "species_10766910", "catalyst" ] ], "additional_components": [ "YNL280C" ] }, "reaction_10773596": { "compartment": "compartment_20699", "id": "reaction_10773596", "reactome": "R-SCE-1676152", "name": "PI4KB binds to ARF1/3:GTP at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773594", "species_10773521" ], "products": [ "species_10773523" ], "modifiers": [], "additional_components": [ "YNL267W", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996", "P39104", "YNL267W", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10761653": { "compartment": "compartment_5460", "id": "reaction_10761653", "reactome": "R-SCE-70967", "name": "isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29938", "species_113526" ], "products": [ "species_113594", "species_29376", "species_29362", "species_113529" ], "modifiers": [ [ "species_10761650", "catalyst" ], [ "species_113581", "catalyst" ] ], "additional_components": [ "P28241", "YOR136W", "P28834", "IDH1", "species_113527" ] }, "reaction_10774302": { "compartment": "compartment_70101", "id": "reaction_10774302", "reactome": "R-SCE-2408551", "name": "SeMet is converted to AdoSeMet by MAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_5357707", "species_29356" ], "products": [ "species_5357652", "species_111294", "species_29372" ], "modifiers": [ [ "species_10766294", "catalyst" ] ], "additional_components": [ "P19358", "YDR502C", "species_74126", "species_109496", "P10659", "YLR180W" ] }, "reaction_10771159": { "compartment": "compartment_70101", "id": "reaction_10771159", "reactome": "R-SCE-548843", "name": "ACSL3,4 ligate CoA to AA to form AA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_29768", "species_113592" ], "products": [ "species_111294", "species_76577", "species_29356", "species_548819" ], "modifiers": [ [ "species_10771156", "catalyst" ] ], "additional_components": [ "P47912", "YMR246W", "P39002", "YIL009W", "P30624", "YOR317W" ] }, "reaction_10783830": { "compartment": "compartment_12045", "id": "reaction_10783830", "reactome": "R-SCE-6800334", "name": "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6800352", "species_1500578" ], "products": [ "species_76194", "species_76103" ], "modifiers": [ [ "species_10783823", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10773032": { "compartment": "compartment_12045", "id": "reaction_10773032", "reactome": "R-SCE-1482629", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10772937": { "compartment": "compartment_12045", "id": "reaction_10772937", "reactome": "R-SCE-1482539", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498740", "species_1500578" ], "products": [ "species_76194", "species_1483256" ], "modifiers": [ [ "species_10772934", "catalyst" ] ], "additional_components": [ "Q12185", "YDR018C", "P38226", "YBR042C" ] }, "reaction_10764651": { "compartment": "compartment_70101", "id": "reaction_10764651", "reactome": "R-SCE-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_6788782" ], "products": [ "species_113592", "species_6788778" ], "modifiers": [ [ "species_10764648", "catalyst" ] ], "additional_components": [ "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "species_109395", "species_76577", "species_109378", "species_109386", "P26364", "YER170W", "P07170", "YDR226W" ] }, "reaction_10763371": { "compartment": "compartment_70101", "id": "reaction_10763371", "reactome": "R-SCE-73800", "name": "SAICAR => AICAR + Fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111399" ], "products": [ "species_29586", "species_111409" ], "modifiers": [ [ "species_10763368", "catalyst" ] ], "additional_components": [ "Q05911", "YLR359W" ] }, "reaction_10773168": { "compartment": "compartment_12045", "id": "reaction_10773168", "reactome": "R-SCE-1482900", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498740", "species_1524021" ], "modifiers": [ [ "species_10772999", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10766900": { "compartment": "compartment_13231", "id": "reaction_10766900", "reactome": "R-SCE-194674", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194681", "species_194688", "species_194725" ], "products": [ "species_194704", "species_194668" ], "modifiers": [ [ "species_10766897", "catalyst" ] ], "additional_components": [ "YNL280C" ] }, "reaction_10772957": { "compartment": "compartment_12045", "id": "reaction_10772957", "reactome": "R-SCE-1482545", "name": "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_29356" ], "products": [ "species_1524023", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10775612": { "compartment": "compartment_70101", "id": "reaction_10775612", "reactome": "R-SCE-3322041", "name": "Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775533" ], "products": [ "species_10775609", "species_110096" ], "modifiers": [ [ "species_10775533", "catalyst" ], [ "species_30537", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10775536": { "compartment": "compartment_70101", "id": "reaction_10775536", "reactome": "R-SCE-3322003", "name": "Autoglucosylation of GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775531" ], "products": [ "species_110096", "species_10775533" ], "modifiers": [ [ "species_10775531", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P27472", "YLR258W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P27472", "YLR258W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10761781": { "compartment": "compartment_70101", "id": "reaction_10761781", "reactome": "R-SCE-71200", "name": "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_29368", "species_29970" ], "products": [ "species_29366", "species_29356", "species_34351" ], "modifiers": [ [ "species_10761778", "catalyst" ] ], "additional_components": [ "YBL098W" ] }, "reaction_10767519": { "compartment": "compartment_70101", "id": "reaction_10767519", "reactome": "R-SCE-200681", "name": "FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_200665" ], "products": [ "species_29370", "species_174404", "species_29372" ], "modifiers": [ [ "species_10767056", "catalyst" ] ], "additional_components": [ "YOR241W" ] }, "reaction_10761689": { "compartment": "compartment_5460", "id": "reaction_10761689", "reactome": "R-SCE-70982", "name": "Fumarate + H2O <=> (S)-Malate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113588" ], "products": [ "species_113544" ], "modifiers": [ [ "species_10761686", "catalyst" ] ], "additional_components": [ "P08417", "YPL262W" ] }, "reaction_10784728": { "compartment": "compartment_70101", "id": "reaction_10784728", "reactome": "R-SCE-6809254", "name": "MTMR8 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784722", "species_10784724" ], "products": [ "species_10784726" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10769851": { "compartment": "compartment_70101", "id": "reaction_10769851", "reactome": "R-SCE-428214", "name": "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428163", "species_113592" ], "products": [ "species_29370", "species_428275" ], "modifiers": [ [ "species_10769848", "catalyst" ] ], "additional_components": [ "Q12246", "YOR171C", "P47045", "TIM54", "Q06147", "YLR260W" ] }, "reaction_10773157": { "compartment": "compartment_12045", "id": "reaction_10773157", "reactome": "R-SCE-1482884", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10767738": { "compartment": "compartment_876", "id": "reaction_10767738", "reactome": "R-SCE-203613", "name": "depalmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767589" ], "products": [ "species_76168", "species_10767646" ], "modifiers": [ [ "species_10767735", "catalyst" ] ], "additional_components": [ "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_113596", "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_29870", "species_113596", "Q12354", "YLR118C" ] }, "reaction_10763944": { "compartment": "compartment_70101", "id": "reaction_10763944", "reactome": "R-SCE-75125", "name": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500006", "species_29370" ], "products": [ "species_113592", "species_500009" ], "modifiers": [ [ "species_10763053", "catalyst" ] ], "additional_components": [ "species_110096", "species_110094", "CHEBI:58593", "species_109395", "species_109378", "species_109402", "YKL024C" ] }, "reaction_10761637": { "compartment": "compartment_5460", "id": "reaction_10761637", "reactome": "R-SCE-70940", "name": "saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_30176" ], "products": [ "species_113556", "species_113552", "species_29362", "species_113529" ], "modifiers": [ [ "species_10761631", "catalyst" ] ], "additional_components": [ "P38999", "YNR050C" ] }, "reaction_10761851": { "compartment": "compartment_70101", "id": "reaction_10761851", "reactome": "R-SCE-71299", "name": "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_29996" ], "products": [ "species_70106", "species_29732", "species_29364", "species_113528" ], "modifiers": [ [ "species_10761848", "catalyst" ] ], "additional_components": [ "P38720", "YHR183W" ] }, "reaction_10773119": { "compartment": "compartment_70616", "id": "reaction_10773119", "reactome": "R-SCE-1482794", "name": "CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524079", "species_1524072" ], "products": [ "species_1524075", "species_1498773" ], "modifiers": [ [ "species_10773113", "catalyst" ] ], "additional_components": [] }, "reaction_10784773": { "compartment": "compartment_70101", "id": "reaction_10784773", "reactome": "R-SCE-6809778", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6809774", "species_29356" ], "products": [ "species_422529", "species_29372" ], "modifiers": [ [ "species_10784765", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10761717": { "compartment": "compartment_5460", "id": "reaction_10761717", "reactome": "R-SCE-70994", "name": "Succinate <=> Fumarate (with FAD redox reaction on enzyme)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113536" ], "products": [ "species_113588" ], "modifiers": [ [ "species_10761714", "catalyst" ] ], "additional_components": [ "P21801", "YLL041C", "Q00711", "YKL148C", "Q08749", "TIM18", "P33421", "YKL141W", "species_113596" ] }, "reaction_10764120": { "compartment": "compartment_70101", "id": "reaction_10764120", "reactome": "R-SCE-75887", "name": "Conversion of Glycerol to Glycerol-3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116", "species_113592" ], "products": [ "species_29370", "species_76114" ], "modifiers": [ [ "species_10764115", "catalyst" ] ], "additional_components": [ "YHL032C" ] }, "reaction_10763395": { "compartment": "compartment_70101", "id": "reaction_10763395", "reactome": "R-SCE-73828", "name": "adenylosuccinate => adenosine 5'-monophosphate + fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_35141" ], "products": [ "species_29586", "species_76577" ], "modifiers": [ [ "species_10763368", "catalyst" ] ], "additional_components": [ "Q05911", "YLR359W" ] }, "reaction_10767535": { "compartment": "compartment_70101", "id": "reaction_10767535", "reactome": "R-SCE-200735", "name": "SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_197969" ], "products": [ "species_29424", "species_200739" ], "modifiers": [ [ "species_10761810", "catalyst" ] ], "additional_components": [ "P37292", "YBR263W" ] }, "reaction_10773035": { "compartment": "compartment_12045", "id": "reaction_10773035", "reactome": "R-SCE-1482635", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498730", "species_1500578" ], "products": [ "species_76194", "species_1483256" ], "modifiers": [ [ "species_10772934", "catalyst" ] ], "additional_components": [ "Q12185", "YDR018C", "P38226", "YBR042C" ] }, "reaction_10767447": { "compartment": "compartment_70101", "id": "reaction_10767447", "reactome": "R-SCE-200423", "name": "pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767435", "species_113592" ], "products": [ "species_29370", "species_10767442" ], "modifiers": [ [ "species_10767444", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527", "Q00955", "YNR016C", "species_113527", "P34164", "YGL208W", "Q04739", "YER027C", "P32578", "YDR422C", "P12904", "YGL115W", "P38845", "YHR146W", "P06782", "YDR477W", "P53885", "YNL173C" ] }, "reaction_10761230": { "compartment": "compartment_70101", "id": "reaction_10761230", "reactome": "R-SCE-70427", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29548" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10761125", "catalyst" ] ], "additional_components": [ "Q03262", "YMR278W", "species_109496" ] }, "reaction_10773584": { "compartment": "compartment_171062", "id": "reaction_10773584", "reactome": "R-SCE-1676141", "name": "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_1806199", "species_29372" ], "modifiers": [ [ "species_10773463", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10773458": { "compartment": "compartment_876", "id": "reaction_10773458", "reactome": "R-SCE-1675780", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_392417" ], "modifiers": [ [ "species_10773453", "catalyst" ] ], "additional_components": [ "YJL100W" ] }, "reaction_10786908": { "compartment": "compartment_70101", "id": "reaction_10786908", "reactome": "R-SCE-8876789", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6786250", "species_71284" ], "products": [ "species_71285", "species_8876775" ], "modifiers": [ [ "species_10786905", "catalyst" ] ], "additional_components": [ "YNL092W" ] }, "reaction_10767466": { "compartment": "compartment_5460", "id": "reaction_10767466", "reactome": "R-SCE-200474", "name": "NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8938083", "species_113593" ], "products": [ "species_8938090", "species_159450" ], "modifiers": [ [ "species_10767463", "catalyst" ] ], "additional_components": [ "Q06178", "YLR328W", "P53204", "YGR010W", "species_109496" ] }, "reaction_10762169": { "compartment": "compartment_70101", "id": "reaction_10762169", "reactome": "R-SCE-71735", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_113592", "species_29416" ], "products": [ "species_111294", "species_76577", "species_76183" ], "modifiers": [ [ "species_10762166", "catalyst" ] ], "additional_components": [ "P52910", "YLR153C", "Q01574", "YAL054C" ] }, "reaction_10784745": { "compartment": "compartment_876", "id": "reaction_10784745", "reactome": "R-SCE-6809320", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806240", "species_29372" ], "modifiers": [ [ "species_10784742", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10776275": { "compartment": "compartment_70101", "id": "reaction_10776275", "reactome": "R-SCE-3781023", "name": "PPP1R3C binds to glycogen:GYG1:GYS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775552", "species_10776211" ], "products": [ "species_10776273" ], "modifiers": [], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P40036", "YER054C", "Q06216", "YLR273C", "P28006", "YOR178C", "P40187", "YIL045W", "P40036", "YER054C", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10773161": { "compartment": "compartment_12045", "id": "reaction_10773161", "reactome": "R-SCE-1482892", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10767321": { "compartment": "compartment_70101", "id": "reaction_10767321", "reactome": "R-SCE-199803", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10761868", "catalyst" ] ], "additional_components": [ "P46969", "YJL121C", "species_111793" ] }, "reaction_10776271": { "compartment": "compartment_70101", "id": "reaction_10776271", "reactome": "R-SCE-3781018", "name": "EPM2A dimer dephosphorylates phosphoglycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10776268" ], "products": [ "species_10776261", "species_29372" ], "modifiers": [ [ "species_10776268", "catalyst" ] ], "additional_components": [ "P40187", "YIL045W", "P46958", "YJL146W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P46958", "YJL146W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P46958", "YJL146W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10770915": { "compartment": "compartment_70101", "id": "reaction_10770915", "reactome": "R-SCE-453338", "name": "PGYM b dimer:AMP complex <=> PGYM dimer, b form + 2 AMP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770913" ], "products": [ "species_10761929", "species_76577" ], "modifiers": [], "additional_components": [ "P06738", "YPR160W", "species_76577", "P06738", "YPR160W" ] }, "reaction_10781323": { "compartment": "compartment_70101", "id": "reaction_10781323", "reactome": "R-SCE-5694071", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_5694074" ], "products": [ "species_5694130" ], "modifiers": [ [ "species_10781320", "catalyst" ] ], "additional_components": [ "species_158417", "P50107", "YML004C" ] }, "reaction_10773592": { "compartment": "compartment_876", "id": "reaction_10773592", "reactome": "R-SCE-1676149", "name": "PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_202247", "species_29356" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10767316", "catalyst" ] ], "additional_components": [ "YNL128W" ] }, "reaction_10769915": { "compartment": "compartment_984", "id": "reaction_10769915", "reactome": "R-SCE-428690", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419305", "species_109276" ], "products": [ "species_109277", "species_428662" ], "modifiers": [ [ "species_10769912", "catalyst" ] ], "additional_components": [ "Q05521", "YDR284C", "Q04396", "YDR503C" ] }, "reaction_10774502": { "compartment": "compartment_70101", "id": "reaction_10774502", "reactome": "R-SCE-2509827", "name": "ITPA hydrolyses ITP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2509836" ], "products": [ "species_70106", "species_29602", "species_111294" ], "modifiers": [ [ "species_10774499", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P47119", "YJR069C" ] }, "reaction_10773490": { "compartment": "compartment_20699", "id": "reaction_10773490", "reactome": "R-SCE-1675824", "name": "PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806165", "species_29356" ], "products": [ "species_1806217", "species_29372" ], "modifiers": [ [ "species_10773487", "catalyst" ] ], "additional_components": [ "YOL065C" ] }, "reaction_10773049": { "compartment": "compartment_12045", "id": "reaction_10773049", "reactome": "R-SCE-1482685", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10781088": { "compartment": "compartment_70101", "id": "reaction_10781088", "reactome": "R-SCE-5692283", "name": "ALD3A1 oxidises 4HPCP to CXPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5692409", "species_29366", "species_29356" ], "products": [ "species_70106", "species_29364", "species_5692433" ], "modifiers": [ [ "species_10781085", "catalyst" ] ], "additional_components": [ "YMR110C" ] }, "reaction_10774505": { "compartment": "compartment_70101", "id": "reaction_10774505", "reactome": "R-SCE-2509831", "name": "ITPA hydrolyses XTP to XMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509848", "species_29356" ], "products": [ "species_70106", "species_111584", "species_111294" ], "modifiers": [ [ "species_10774499", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P47119", "YJR069C" ] }, "reaction_10766958": { "compartment": "compartment_70101", "id": "reaction_10766958", "reactome": "R-SCE-196761", "name": "2xTPK1:Mg2+ phosphorylates THMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196934" ], "products": [ "species_29480", "species_76577" ], "modifiers": [ [ "species_10766955", "catalyst" ] ], "additional_components": [ "P35202", "YOR143C", "species_109496" ] }, "reaction_10784761": { "compartment": "compartment_171062", "id": "reaction_10784761", "reactome": "R-SCE-6809720", "name": "PI3P is dephosphorylated to PI by MTM1:MTMR12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_1806199", "species_29372" ], "modifiers": [ [ "species_10784752", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10764851": { "compartment": "compartment_70101", "id": "reaction_10764851", "reactome": "R-SCE-111524", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29602", "species_29438", "species_29448" ], "products": [ "species_70106", "species_35141", "species_29372", "species_29420" ], "modifiers": [ [ "species_10764848", "catalyst" ], [ "species_29420", "inhibitor" ], [ "species_113578", "inhibitor" ], [ "species_35141", "inhibitor" ], [ "species_30014", "inhibitor" ] ], "additional_components": [ "P80210", "YNL220W", "species_109496" ] }, "reaction_10786559": { "compartment": "compartment_70101", "id": "reaction_10786559", "reactome": "R-SCE-8869627", "name": "NMRK2 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_70106", "species_29370", "species_8869353" ], "modifiers": [ [ "species_10786553", "catalyst" ] ], "additional_components": [ "YNL129W" ] }, "reaction_10761438": { "compartment": "compartment_5460", "id": "reaction_10761438", "reactome": "R-SCE-70542", "name": "glutamate + acetyl CoA => N-acetyl glutamate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113559" ], "products": [ "species_29374", "species_30471" ], "modifiers": [ [ "species_10761435", "catalyst" ], [ "species_374064", "catalyst" ] ], "additional_components": [ "YER069W" ] }, "reaction_10773539": { "compartment": "compartment_171062", "id": "reaction_10773539", "reactome": "R-SCE-1675974", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806180" ], "modifiers": [ [ "species_10773453", "catalyst" ] ], "additional_components": [ "YJL100W" ] }, "reaction_10773138": { "compartment": "compartment_70616", "id": "reaction_10773138", "reactome": "R-SCE-1482847", "name": "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524085", "species_1524047" ], "modifiers": [ [ "species_10773088", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10770921": { "compartment": "compartment_70101", "id": "reaction_10770921", "reactome": "R-SCE-453339", "name": "poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762038", "species_29372" ], "products": [ "species_10770919", "species_29548" ], "modifiers": [ [ "species_10762009", "catalyst" ] ], "additional_components": [ "P47011", "YJL137C", "species_113527", "P47011", "YJL137C", "species_113527", "P06738", "YPR160W" ] }, "reaction_10761311": { "compartment": "compartment_70101", "id": "reaction_10761311", "reactome": "R-SCE-70467", "name": "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_29370", "species_30014" ], "modifiers": [ [ "species_10761308", "catalyst" ], [ "species_30533", "catalyst" ], [ "species_29370", "catalyst" ], [ "species_76577", "catalyst" ], [ "species_113592", "inhibitor" ], [ "species_76190", "inhibitor" ] ], "additional_components": [ "P16861", "YGR240C", "P16862", "YMR205C" ] }, "reaction_10766705": { "compartment": "compartment_70101", "id": "reaction_10766705", "reactome": "R-SCE-191322", "name": "FDPS dimer transfers IPPP to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191324" ], "products": [ "species_191409", "species_111294" ], "modifiers": [ [ "species_10766699", "catalyst" ] ], "additional_components": [ "P08524", "YJL167W", "species_109496" ] }, "reaction_10772005": { "compartment": "compartment_70101", "id": "reaction_10772005", "reactome": "R-SCE-965079", "name": "2xPNPO:2xFMN oxidizes PXAP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965146", "species_29368", "species_29356" ], "products": [ "species_29408", "species_31633", "species_29390" ], "modifiers": [ [ "species_10772000", "catalyst" ] ], "additional_components": [ "species_73524", "P38075", "YBR035C" ] }, "reaction_10764030": { "compartment": "compartment_70101", "id": "reaction_10764030", "reactome": "R-SCE-75849", "name": "Transport of Citrate from Mitochondrial Matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29654", "species_198498" ], "products": [ "species_76190", "species_113544" ], "modifiers": [ [ "species_10764027", "catalyst" ] ], "additional_components": [ "YBR291C" ] }, "reaction_10771299": { "compartment": "compartment_70101", "id": "reaction_10771299", "reactome": "R-SCE-888614", "name": "IDO2 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29500" ], "products": [ "species_33179" ], "modifiers": [ [ "species_10771296", "catalyst" ] ], "additional_components": [ "P47125", "YJR078W", "species_189444" ] }, "reaction_10768921": { "compartment": "compartment_17951", "id": "reaction_10768921", "reactome": "R-SCE-389609", "name": "ALDH3A2-2 oxidizes pristanal to pristanate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389636", "species_192307" ], "products": [ "species_193465", "species_6811612", "species_192305" ], "modifiers": [ [ "species_10768918", "catalyst" ] ], "additional_components": [ "Q04458", "YMR110C" ] }, "reaction_10767051": { "compartment": "compartment_70101", "id": "reaction_10767051", "reactome": "R-SCE-197271", "name": "NADSYN1 hexamer amidates NAAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197256", "species_29472", "species_113592", "species_29356" ], "products": [ "species_29404", "species_111294", "species_29360", "species_76577" ], "modifiers": [ [ "species_10767048", "catalyst" ] ], "additional_components": [ "P38795", "YHR074W" ] }, "reaction_10767059": { "compartment": "compartment_70101", "id": "reaction_10767059", "reactome": "R-SCE-197958", "name": "FPGS-2 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_111355" ], "products": [ "species_29370", "species_197969", "species_29372" ], "modifiers": [ [ "species_10767056", "catalyst" ] ], "additional_components": [ "YOR241W" ] }, "reaction_10763076": { "compartment": "compartment_70101", "id": "reaction_10763076", "reactome": "R-SCE-73577", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_111627", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_29372", "species_111647" ], "modifiers": [ [ "species_10763067", "catalyst" ] ], "additional_components": [ "P07259", "YJL130C", "P03965", "YJR109C" ] }, "reaction_10766605": { "compartment": "compartment_70101", "id": "reaction_10766605", "reactome": "R-SCE-190182", "name": "UROD decarboxylates URO1 to COPRO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190157" ], "products": [ "species_113528", "species_190128" ], "modifiers": [ [ "species_10766550", "catalyst" ] ], "additional_components": [ "P32347", "YDR047W" ] }, "reaction_10766872": { "compartment": "compartment_70101", "id": "reaction_10766872", "reactome": "R-SCE-193961", "name": "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196366" ], "products": [ "species_193092" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10773558": { "compartment": "compartment_172574", "id": "reaction_10773558", "reactome": "R-SCE-1676065", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806289" ], "products": [ "species_1806212", "species_29372" ], "modifiers": [ [ "species_10773463", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10773091": { "compartment": "compartment_70616", "id": "reaction_10773091", "reactome": "R-SCE-1482745", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524085", "species_1524027" ], "modifiers": [ [ "species_10773088", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10784326": { "compartment": "compartment_5460", "id": "reaction_10784326", "reactome": "R-SCE-6806967", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807477", "species_113593" ], "products": [ "species_113548", "species_113600", "species_113581", "species_113529" ], "modifiers": [ [ "species_10784323", "catalyst" ] ], "additional_components": [ "YKL151C" ] }, "reaction_10761600": { "compartment": "compartment_70101", "id": "reaction_10761600", "reactome": "R-SCE-70723", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_508182", "species_29406" ], "products": [ "species_29404", "species_508187" ], "modifiers": [ [ "species_10761597", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "species_351964", "CHEBI:57762", "CHEBI:28654", "CHEBI:16530", "CHEBI:17865", "P38891", "YHR208W" ] }, "reaction_10773166": { "compartment": "compartment_12045", "id": "reaction_10773166", "reactome": "R-SCE-1482897", "name": "PS is hydrolyzed to 2-acyl LPS by PLA2[10]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_29356" ], "products": [ "species_1498722", "species_1524021" ], "modifiers": [ [ "species_10773124", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10763142": { "compartment": "compartment_70101", "id": "reaction_10763142", "reactome": "R-SCE-73605", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109382", "species_111355" ], "products": [ "species_109366", "species_73604" ], "modifiers": [ [ "species_10763139", "catalyst" ] ], "additional_components": [ "P06785", "YOR074C", "species_109496" ] }, "reaction_10767724": { "compartment": "compartment_20699", "id": "reaction_10767724", "reactome": "R-SCE-203567", "name": "palmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767644", "species_200993" ], "products": [ "species_10767716" ], "modifiers": [ [ "species_10767721", "catalyst" ] ], "additional_components": [ "YHR042W", "YHR042W", "YLR246W" ] }, "reaction_10767524": { "compartment": "compartment_5460", "id": "reaction_10767524", "reactome": "R-SCE-200682", "name": "Mitochondrial FPGS-1 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_200671", "species_113593" ], "products": [ "species_113548", "species_200679", "species_113581" ], "modifiers": [ [ "species_10767521", "catalyst" ] ], "additional_components": [ "YOR241W" ] }, "reaction_10763403": { "compartment": "compartment_5460", "id": "reaction_10763403", "reactome": "R-SCE-73918", "name": "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73871", "species_113559" ], "products": [ "species_29374", "species_73917" ], "modifiers": [ [ "species_10763400", "catalyst" ] ], "additional_components": [ "YML126C" ] }, "reaction_10785542": { "compartment": "compartment_984", "id": "reaction_10785542", "reactome": "R-SCE-8851110", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785539", "catalyst" ] ], "additional_components": [ "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10773526": { "compartment": "compartment_20699", "id": "reaction_10773526", "reactome": "R-SCE-1675883", "name": "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10773523", "catalyst" ] ], "additional_components": [ "P39104", "YNL267W", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10770990": { "compartment": "compartment_70101", "id": "reaction_10770990", "reactome": "R-SCE-482619", "name": "(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_482627", "species_113592" ], "products": [ "species_29370", "species_482625" ], "modifiers": [ [ "species_10770987", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:60471", "CHEBI:58369", "CHEBI:58595", "CHEBI:57667", "species_110096", "species_110094", "CHEBI:58593", "species_29494", "species_500739", "species_29892", "species_110644", "species_30185", "species_30187", "species_29438", "species_110614", "P36010", "YKL067W" ] }, "reaction_10769859": { "compartment": "compartment_70101", "id": "reaction_10769859", "reactome": "R-SCE-428262", "name": "phytoceramide + H2O => stearate + phytosphingosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025544", "species_29356" ], "products": [ "species_3632878", "species_428237" ], "modifiers": [ [ "species_10769856", "catalyst" ] ], "additional_components": [ "YPL087W" ] }, "reaction_10776266": { "compartment": "compartment_70101", "id": "reaction_10776266", "reactome": "R-SCE-3781011", "name": "EPM2A dimer dephosphorylates phosphoglycogen-GYG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10776263" ], "products": [ "species_10776227", "species_29372" ], "modifiers": [ [ "species_10776263", "catalyst" ] ], "additional_components": [ "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10767041": { "compartment": "compartment_70101", "id": "reaction_10767041", "reactome": "R-SCE-197268", "name": "QPRT transfers PRIB to QUIN to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73566", "species_197238" ], "products": [ "species_113528", "species_111294", "species_197220" ], "modifiers": [ [ "species_10767038", "catalyst" ] ], "additional_components": [ "YFR047C" ] }, "reaction_10785578": { "compartment": "compartment_984", "id": "reaction_10785578", "reactome": "R-SCE-8851538", "name": "NTPDase8 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9726184", "species_109276" ], "products": [ "species_9726189", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785532", "catalyst" ] ], "additional_components": [ "species_29494", "species_30187", "species_113592", "species_2509836", "species_29438", "species_110614", "species_29420", "CHEBI:58369", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10774297": { "compartment": "compartment_5460", "id": "reaction_10774297", "reactome": "R-SCE-2395512", "name": "FDXR transfers electrons to FDX1,2 (FDX1L)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774293", "species_10772859" ], "products": [ "species_10772851", "species_10774295", "species_113529" ], "modifiers": [], "additional_components": [ "P48360", "YDR376W", "species_31649", "CHEBI:33737", "Q12184", "YPL252C", "CHEBI:33738", "Q12184", "YPL252C", "P48360", "YDR376W", "species_113596" ] }, "reaction_10771310": { "compartment": "compartment_70101", "id": "reaction_10771310", "reactome": "R-SCE-893593", "name": "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29502", "species_29398" ], "products": [ "species_893599", "species_29432" ], "modifiers": [ [ "species_10771307", "catalyst" ] ], "additional_components": [ "P47039", "YJL060W" ] }, "reaction_10781200": { "compartment": "compartment_70101", "id": "reaction_10781200", "reactome": "R-SCE-5693390", "name": "HSD17B11 dehydrogenates EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_193132" ], "products": [ "species_70106", "species_29364", "species_193066" ], "modifiers": [ [ "species_10781197", "catalyst" ] ], "additional_components": [ "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C" ] }, "reaction_10773448": { "compartment": "compartment_876", "id": "reaction_10773448", "reactome": "R-SCE-1675776", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806240" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10773445", "catalyst" ] ], "additional_components": [ "P38994", "YDR208W" ] }, "reaction_10787145": { "compartment": "compartment_70101", "id": "reaction_10787145", "reactome": "R-SCE-8939959", "name": "NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869353" ], "products": [ "species_111294", "species_29360" ], "modifiers": [ [ "species_10767030", "catalyst" ] ], "additional_components": [ "Q06178", "YLR328W", "P53204", "YGR010W", "species_109496" ] }, "reaction_10788787": { "compartment": "compartment_70101", "id": "reaction_10788787", "reactome": "R-SCE-9638127", "name": "PGM1:Mg2+ isomerises G6P to G1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537" ], "products": [ "species_29548" ], "modifiers": [ [ "species_10788782", "catalyst" ] ], "additional_components": [ "P33401", "YKL127W", "species_109496" ] }, "reaction_10784736": { "compartment": "compartment_17951", "id": "reaction_10784736", "reactome": "R-SCE-6809287", "name": "NUDT12 hydrolyses NADH to NMNH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389620", "species_141343", "species_192305" ], "products": [ "species_6809289", "species_193465" ], "modifiers": [ [ "species_10784733", "catalyst" ] ], "additional_components": [ "YGL067W" ] }, "reaction_10767473": { "compartment": "compartment_7660", "id": "reaction_10767473", "reactome": "R-SCE-200512", "name": "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_200492" ], "products": [ "species_200499", "species_113541" ], "modifiers": [ [ "species_10767470", "catalyst" ] ], "additional_components": [ "species_158417", "Q06178", "YLR328W" ] }, "reaction_10773601": { "compartment": "compartment_876", "id": "reaction_10773601", "reactome": "R-SCE-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10773598", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "P50942", "YNL106C" ] }, "reaction_10774843": { "compartment": "compartment_70101", "id": "reaction_10774843", "reactome": "R-SCE-2993814", "name": "HLCS biotinylates ACACA:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_113592", "species_10774841" ], "products": [ "species_10764051", "species_111294", "species_76577" ], "modifiers": [ [ "species_10774830", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527", "P32874", "YMR207C", "Q00955", "YNR016C", "species_113527", "P32874", "YMR207C", "YDL141W" ] }, "reaction_10771961": { "compartment": "compartment_70101", "id": "reaction_10771961", "reactome": "R-SCE-947514", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_10771945" ], "products": [ "species_10771950", "species_29432" ], "modifiers": [ [ "species_10771958", "catalyst" ] ], "additional_components": [ "species_158417", "P38820", "YHR111W", "species_158417", "P38820", "YHR111W", "P25374", "YCL017C" ] }, "reaction_10773561": { "compartment": "compartment_876", "id": "reaction_10773561", "reactome": "R-SCE-1676082", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10773418", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10774121": { "compartment": "compartment_17951", "id": "reaction_10774121", "reactome": "R-SCE-2066779", "name": "Conversion of DHA-CoA to docosahexaenoic acid (DHA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_2066765" ], "products": [ "species_193514", "species_2066763" ], "modifiers": [ [ "species_10766854", "catalyst" ] ], "additional_components": [ "YJR019C" ] }, "reaction_10773542": { "compartment": "compartment_876", "id": "reaction_10773542", "reactome": "R-SCE-1675988", "name": "PI4P is dephosphorylated to PI by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_392417" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10773511", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "Q08227", "YOL065C", "P50942", "YNL106C" ] }, "reaction_10762104": { "compartment": "compartment_70101", "id": "reaction_10762104", "reactome": "R-SCE-71691", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29510", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_29416" ], "modifiers": [ [ "species_10762101", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10769022": { "compartment": "compartment_17951", "id": "reaction_10769022", "reactome": "R-SCE-389862", "name": "Conversion of glyoxylate to oxalate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389678", "species_141343", "species_113535" ], "products": [ "species_389819", "species_113575" ], "modifiers": [ [ "species_10769016", "catalyst" ] ], "additional_components": [ "species_73524", "P00175", "CYB2" ] }, "reaction_10767564": { "compartment": "compartment_70101", "id": "reaction_10767564", "reactome": "R-SCE-201035", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_3632881", "species_113592" ], "products": [ "species_111294", "species_76577", "species_29356", "species_200993" ], "modifiers": [ [ "species_10767561", "catalyst" ] ], "additional_components": [ "P47912", "YMR246W", "P39002", "YIL009W", "P30624", "YOR317W", "P39518", "YER015W" ] }, "reaction_10761112": { "compartment": "compartment_70101", "id": "reaction_10761112", "reactome": "R-SCE-70262", "name": "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30533", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10761109", "catalyst" ] ], "additional_components": [ "P32604", "YJL155C" ] }, "reaction_10768062": { "compartment": "compartment_70101", "id": "reaction_10768062", "reactome": "R-SCE-209792", "name": "N-acetylation of serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183", "species_209914" ], "products": [ "species_76194", "species_209793" ], "modifiers": [ [ "species_10768059", "catalyst" ] ], "additional_components": [ "YDR071C" ] }, "reaction_10774508": { "compartment": "compartment_70101", "id": "reaction_10774508", "reactome": "R-SCE-2509838", "name": "ITPA hydrolyses dITP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509835", "species_29356" ], "products": [ "species_70106", "species_9731659", "species_111294" ], "modifiers": [ [ "species_10774499", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P47119", "YJR069C" ] }, "reaction_10785581": { "compartment": "compartment_984", "id": "reaction_10785581", "reactome": "R-SCE-8851550", "name": "NTPDase8 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9726189", "species_109276" ], "products": [ "species_109277", "species_351626", "species_9726186" ], "modifiers": [ [ "species_10785532", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58369", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "species_109366", "species_109395", "species_29602", "species_76577", "species_109402", "species_113578", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10761792": { "compartment": "compartment_70101", "id": "reaction_10761792", "reactome": "R-SCE-71217", "name": "3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_34351" ], "products": [ "species_30487", "species_29432" ], "modifiers": [ [ "species_10761789", "catalyst" ] ], "additional_components": [ "Q05979", "YLR231C" ] }, "reaction_10763309": { "compartment": "compartment_70101", "id": "reaction_10763309", "reactome": "R-SCE-73788", "name": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500071", "species_113592" ], "products": [ "species_500077", "species_29370" ], "modifiers": [ [ "species_10763306", "catalyst" ] ], "additional_components": [ "CHEBI:57673", "species_113578", "species_29420", "CHEBI:58595", "YDR454C" ] }, "reaction_10766758": { "compartment": "compartment_70101", "id": "reaction_10766758", "reactome": "R-SCE-191402", "name": "Reduction of presqualene diphosphate to form squalene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_191265", "species_29364" ], "products": [ "species_29366", "species_191269", "species_111294" ], "modifiers": [ [ "species_10766755", "catalyst" ] ], "additional_components": [ "P29704", "YHR190W", "species_109496" ] }, "reaction_10766487": { "compartment": "compartment_5460", "id": "reaction_10766487", "reactome": "R-SCE-188467", "name": "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_188458" ], "products": [ "species_188451", "species_31649" ], "modifiers": [ [ "species_10766484", "catalyst" ] ], "additional_components": [ "YIL155C" ] }, "reaction_10781600": { "compartment": "compartment_70101", "id": "reaction_10781600", "reactome": "R-SCE-5694583", "name": "ABHD4 hydrolyses NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694568" ], "products": [ "species_5694580", "species_5694567" ], "modifiers": [ [ "species_10781597", "catalyst" ] ], "additional_components": [ "Q12385", "YLR099C", "Q04623", "YDR125C", "P53264", "YGR110W", "P53208", "YGR015C" ] }, "reaction_10773609": { "compartment": "compartment_876", "id": "reaction_10773609", "reactome": "R-SCE-1676203", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806240", "species_29372" ], "modifiers": [ [ "species_10773550", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "P47147", "YJR110W", "P50942", "YNL106C" ] }, "reaction_10764056": { "compartment": "compartment_70101", "id": "reaction_10764056", "reactome": "R-SCE-75851", "name": "Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10764053", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527", "P32874", "YMR207C" ] }, "reaction_10771185": { "compartment": "compartment_70101", "id": "reaction_10771185", "reactome": "R-SCE-549192", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76103", "species_75967" ], "products": [ "species_76194", "species_549167" ], "modifiers": [ [ "species_10771182", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10763172": { "compartment": "compartment_7660", "id": "reaction_10763172", "reactome": "R-SCE-73666", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_500739" ], "products": [ "species_113541", "species_500742", "species_9668967" ], "modifiers": [ [ "species_10763169", "catalyst" ] ], "additional_components": [ "P33317", "YBR252W" ] }, "reaction_10761773": { "compartment": "compartment_70101", "id": "reaction_10761773", "reactome": "R-SCE-71146", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71112" ], "products": [ "species_29356", "species_71129" ], "modifiers": [ [ "species_10761770", "catalyst" ] ], "additional_components": [ "P38744", "YHL018W" ] }, "reaction_10773002": { "compartment": "compartment_17906", "id": "reaction_10773002", "reactome": "R-SCE-1482604", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590", "species_29356" ], "products": [ "species_1524103", "species_1500580" ], "modifiers": [ [ "species_10772999", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10764827": { "compartment": "compartment_70101", "id": "reaction_10764827", "reactome": "R-SCE-111215", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_110644" ], "products": [ "species_73566", "species_109386" ], "modifiers": [ [ "species_10763105", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_29372", "catalyst" ] ], "additional_components": [ "P38063", "YBL068W", "P32895", "YKL181W", "P38689", "YHL011C", "Q12265", "YOL061W", "P38620", "YER099C" ] }, "reaction_10774851": { "compartment": "compartment_5460", "id": "reaction_10774851", "reactome": "R-SCE-2995330", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_2162257", "species_189444" ], "products": [ "species_2995328", "species_159450" ], "modifiers": [ [ "species_10774848", "catalyst" ] ], "additional_components": [ "YPL172C" ] }, "reaction_10761624": { "compartment": "compartment_5460", "id": "reaction_10761624", "reactome": "R-SCE-70881", "name": "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71847", "species_113521" ], "products": [ "species_29374", "species_573404" ], "modifiers": [ [ "species_10761621", "catalyst" ] ], "additional_components": [ "YDR036C" ] }, "reaction_10767280": { "compartment": "compartment_70101", "id": "reaction_10767280", "reactome": "R-SCE-198824", "name": "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10767267" ], "products": [ "species_29360", "species_10767269" ], "modifiers": [ [ "species_10767277", "catalyst" ] ], "additional_components": [ "CHEBI:36144", "P40312", "YNL111C", "species_189444", "P40312", "YNL111C", "P38626", "YIL043C", "species_113596" ] }, "reaction_10785569": { "compartment": "compartment_984", "id": "reaction_10785569", "reactome": "R-SCE-8851396", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851462", "species_109276" ], "products": [ "species_109277", "species_351626", "species_8851461" ], "modifiers": [ [ "species_10785566", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58280", "species_110094", "species_110096", "species_109395", "species_29602", "species_109402", "species_113578", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10774119": { "compartment": "compartment_17951", "id": "reaction_10774119", "reactome": "R-SCE-2066778", "name": "Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2066767", "species_141343" ], "products": [ "species_2066766" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10787695": { "compartment": "compartment_5460", "id": "reaction_10787695", "reactome": "R-SCE-8955817", "name": "PRODH2 oxidises HPRO to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784215", "species_113597" ], "products": [ "species_164934", "species_113521", "species_113590" ], "modifiers": [ [ "species_10781897", "catalyst" ] ], "additional_components": [ "YLR142W" ] }, "reaction_10772003": { "compartment": "compartment_70101", "id": "reaction_10772003", "reactome": "R-SCE-965019", "name": "2xPNPO:2xFMN oxidizes PDXP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964952", "species_29368" ], "products": [ "species_29408", "species_29390" ], "modifiers": [ [ "species_10772000", "catalyst" ] ], "additional_components": [ "species_73524", "P38075", "YBR035C" ] }, "reaction_10771152": { "compartment": "compartment_70101", "id": "reaction_10771152", "reactome": "R-SCE-548831", "name": "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_548809" ], "products": [ "species_29366", "species_428139" ], "modifiers": [ [ "species_10771147", "catalyst" ] ], "additional_components": [ "YDL015C" ] }, "reaction_10761763": { "compartment": "compartment_5460", "id": "reaction_10761763", "reactome": "R-SCE-71037", "name": "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113526", "species_70951" ], "products": [ "species_70955", "species_29376", "species_29362" ], "modifiers": [ [ "species_10761760", "catalyst" ] ], "additional_components": [ "species_29480", "P20967", "YIL125W", "CHEBI:17460", "P09624", "YFL018C", "species_113596", "P19262", "YDR148C" ] }, "reaction_10767016": { "compartment": "compartment_70101", "id": "reaction_10767016", "reactome": "R-SCE-197198", "name": "NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29360" ], "products": [ "species_29370", "species_29366" ], "modifiers": [ [ "species_10767013", "catalyst" ] ], "additional_components": [ "species_158417", "P21373", "YJR049C" ] }, "reaction_10784758": { "compartment": "compartment_70101", "id": "reaction_10784758", "reactome": "R-SCE-6809707", "name": "MTMR12 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784750", "species_10773465" ], "products": [ "species_10784756" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10782032": { "compartment": "compartment_7660", "id": "reaction_10782032", "reactome": "R-SCE-6788810", "name": "AK6 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788813", "species_29358" ], "products": [ "species_113582", "species_6788807" ], "modifiers": [ [ "species_10782029", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "YDL166C" ] }, "reaction_10768262": { "compartment": "compartment_70101", "id": "reaction_10768262", "reactome": "R-SCE-266072", "name": "LTA4 is hydolysed to LTB4 by LTA4H", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265281", "species_29356" ], "products": [ "species_266056" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10787954": { "compartment": "compartment_5460", "id": "reaction_10787954", "reactome": "R-SCE-9012016", "name": "FAHD1:Zn2+ dimer hydrolyses OA to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587" ], "products": [ "species_29376", "species_113557" ], "modifiers": [ [ "species_10787951", "catalyst" ] ], "additional_components": [ "P53889", "YNL168C", "species_109496" ] }, "reaction_10784681": { "compartment": "compartment_70101", "id": "reaction_10784681", "reactome": "R-SCE-6808496", "name": "ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_111353", "species_29356" ], "products": [ "species_70106", "species_29364", "species_113528", "species_197969" ], "modifiers": [ [ "species_10784678", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10784137": { "compartment": "compartment_5460", "id": "reaction_10784137", "reactome": "R-SCE-6801328", "name": "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693984", "species_113526" ], "products": [ "species_6801458", "species_29362" ], "modifiers": [ [ "species_10784132", "catalyst" ] ], "additional_components": [ "YBR084W" ] }, "reaction_10763379": { "compartment": "compartment_70101", "id": "reaction_10763379", "reactome": "R-SCE-73810", "name": "FGAM + ATP => AIR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111369" ], "products": [ "species_70106", "species_29370", "species_111370", "species_29372" ], "modifiers": [ [ "species_10763376", "catalyst" ] ], "additional_components": [ "YGL234W" ] }, "reaction_10771277": { "compartment": "compartment_5460", "id": "reaction_10771277", "reactome": "R-SCE-880007", "name": "(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_879997" ], "products": [ "species_113594", "species_31649" ], "modifiers": [ [ "species_10771274", "catalyst" ], [ "species_880069", "catalyst" ], [ "species_113527", "catalyst" ], [ "species_880067", "catalyst" ] ], "additional_components": [ "YDL178W" ] }, "reaction_10766543": { "compartment": "compartment_17927", "id": "reaction_10766543", "reactome": "R-SCE-189423", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189478" ], "products": [ "species_189481", "species_189463" ], "modifiers": [ [ "species_10766540", "catalyst" ] ], "additional_components": [ "P40012", "YER014W", "species_113596" ] }, "reaction_10773316": { "compartment": "compartment_12045", "id": "reaction_10773316", "reactome": "R-SCE-1483190", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_428686" ], "products": [ "species_111294", "species_1500603" ], "modifiers": [ [ "species_10773313", "catalyst" ] ], "additional_components": [ "P33412", "YGR007W" ] }, "reaction_10773052": { "compartment": "compartment_70616", "id": "reaction_10773052", "reactome": "R-SCE-1482689", "name": "1-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524027", "species_1524038" ], "products": [ "species_1524042", "species_29374" ], "modifiers": [ [ "species_10772962", "catalyst" ] ], "additional_components": [ "YDL142C" ] }, "reaction_10768252": { "compartment": "compartment_876", "id": "reaction_10768252", "reactome": "R-SCE-266070", "name": "LTC4 is exported from the cytosol by ABCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266066" ], "products": [ "species_266013" ], "modifiers": [ [ "species_10768249", "catalyst" ] ], "additional_components": [ "YDR135C" ] }, "reaction_10761148": { "compartment": "compartment_70101", "id": "reaction_10761148", "reactome": "R-SCE-70349", "name": "DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_30393" ], "products": [ "species_29370", "species_29578" ], "modifiers": [ [ "species_10761145", "catalyst" ] ], "additional_components": [ "P54838", "YML070W", "species_109496" ] }, "reaction_10766599": { "compartment": "compartment_70101", "id": "reaction_10766599", "reactome": "R-SCE-189488", "name": "UROS transforms HMB to URO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189449" ], "products": [ "species_189407", "species_29356" ], "modifiers": [ [ "species_10766596", "catalyst" ] ], "additional_components": [ "YOR278W" ] }, "reaction_10773148": { "compartment": "compartment_12045", "id": "reaction_10773148", "reactome": "R-SCE-1482861", "name": "MLCL is acylated to CL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524069", "species_1500578" ], "products": [ "species_76194", "species_1524081" ], "modifiers": [ [ "species_10764105", "catalyst" ] ], "additional_components": [ "YBR042C" ] }, "reaction_10784649": { "compartment": "compartment_13977", "id": "reaction_10784649", "reactome": "R-SCE-6808464", "name": "ALDH3B2 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_29356", "species_6808468" ], "products": [ "species_70106", "species_73473", "species_2453691" ], "modifiers": [ [ "species_10784646", "catalyst" ] ], "additional_components": [ "YMR110C" ] }, "reaction_10773056": { "compartment": "compartment_12045", "id": "reaction_10773056", "reactome": "R-SCE-1482696", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10764653": { "compartment": "compartment_70101", "id": "reaction_10764653", "reactome": "R-SCE-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6788778" ], "products": [ "species_29370", "species_6788782" ], "modifiers": [ [ "species_10764648", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "P26364", "YER170W", "P07170", "YDR226W" ] }, "reaction_10787680": { "compartment": "compartment_70101", "id": "reaction_10787680", "reactome": "R-SCE-8954327", "name": "UCKL1 phosphorylates urindine, cytidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500759", "species_113592" ], "products": [ "species_29370", "species_500761" ], "modifiers": [ [ "species_10787677", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:16704", "species_109395", "species_109402", "YNR012W" ] }, "reaction_10762000": { "compartment": "compartment_70101", "id": "reaction_10762000", "reactome": "R-SCE-71552", "name": "limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761969" ], "products": [ "species_10761992" ], "modifiers": [ [ "species_10761997", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_113527", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_113527", "P36143", "YKR058W", "YPR184W" ] }, "reaction_10776278": { "compartment": "compartment_70101", "id": "reaction_10776278", "reactome": "R-SCE-3781024", "name": "GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10776273" ], "products": [ "species_10776259", "species_109402" ], "modifiers": [ [ "species_10776273", "catalyst" ] ], "additional_components": [ "P40187", "YIL045W", "P40036", "YER054C", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P46958", "YJL146W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P40036", "YER054C", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10787833": { "compartment": "compartment_70101", "id": "reaction_10787833", "reactome": "R-SCE-8982667", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787326" ], "products": [ "species_6787328" ], "modifiers": [ [ "species_10761119", "catalyst" ] ], "additional_components": [ "Q03262", "YMR278W", "species_109496" ] }, "reaction_10788340": { "compartment": "compartment_70101", "id": "reaction_10788340", "reactome": "R-SCE-9018862", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9022655" ], "products": [ "species_9022660" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10773563": { "compartment": "compartment_171062", "id": "reaction_10773563", "reactome": "R-SCE-1676105", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806205", "species_29356" ], "products": [ "species_1806259", "species_29372" ], "modifiers": [ [ "species_10773463", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10774859": { "compartment": "compartment_5460", "id": "reaction_10774859", "reactome": "R-SCE-2995334", "name": "COX15 transforms heme O to heme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2995328" ], "products": [ "species_2995348" ], "modifiers": [ [ "species_10774856", "catalyst" ] ], "additional_components": [ "YER141W" ] }, "reaction_10781907": { "compartment": "compartment_5460", "id": "reaction_10781907", "reactome": "R-SCE-6784393", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587", "species_6784236" ], "products": [ "species_6784229", "species_113553" ], "modifiers": [ [ "species_10761497", "catalyst" ] ], "additional_components": [ "Q01802", "YKL106W" ] }, "reaction_10773380": { "compartment": "compartment_70101", "id": "reaction_10773380", "reactome": "R-SCE-1614524", "name": "PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369", "species_200736" ], "products": [ "species_1614518", "species_29356" ], "modifiers": [ [ "species_10773377", "catalyst" ] ], "additional_components": [ "P32582", "YGR155W", "species_189444" ] }, "reaction_10775560": { "compartment": "compartment_70101", "id": "reaction_10775560", "reactome": "R-SCE-3322005", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775513" ], "products": [ "species_10775552" ], "modifiers": [ [ "species_10775557", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "YEL011W" ] }, "reaction_10782009": { "compartment": "compartment_70101", "id": "reaction_10782009", "reactome": "R-SCE-6788295", "name": "HDHD1:Mg2+ dephosphorylates PURIDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788291", "species_29356" ], "products": [ "species_29372", "species_6788290" ], "modifiers": [ [ "species_10782006", "catalyst" ] ], "additional_components": [ "Q86ZR7", "YKL033W-A", "species_109496" ] }, "reaction_10781636": { "compartment": "compartment_12045", "id": "reaction_10781636", "reactome": "R-SCE-5696424", "name": "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696426", "species_192172" ], "products": [ "species_162743", "species_5696412" ], "modifiers": [ [ "species_10781633", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10771046": { "compartment": "compartment_876", "id": "reaction_10771046", "reactome": "R-SCE-499981", "name": "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10771043", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10782630": { "compartment": "compartment_5460", "id": "reaction_10782630", "reactome": "R-SCE-6793591", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6793610", "species_10782620", "species_2162265" ], "products": [ "species_10781283", "species_6793613", "species_379705" ], "modifiers": [ [ "species_10782627", "catalyst" ] ], "additional_components": [ "YAL044C", "YAL044C", "CHEBI:49883", "P32875", "YOR196C" ] }, "reaction_10769056": { "compartment": "compartment_17951", "id": "reaction_10769056", "reactome": "R-SCE-390252", "name": "HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390249", "species_141343" ], "products": [ "species_390248" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10772015": { "compartment": "compartment_70101", "id": "reaction_10772015", "reactome": "R-SCE-977324", "name": "PSPH:Mg2+ dimer dephosphorylates O-P-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_936706" ], "products": [ "species_200736", "species_29372" ], "modifiers": [ [ "species_10772012", "catalyst" ] ], "additional_components": [ "P42941", "YGR208W", "species_109496" ] }, "reaction_10766979": { "compartment": "compartment_70101", "id": "reaction_10766979", "reactome": "R-SCE-196929", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73524", "species_113592" ], "products": [ "species_29386", "species_111294" ], "modifiers": [ [ "species_10766976", "catalyst" ] ], "additional_components": [ "YDL045C" ] }, "reaction_10781999": { "compartment": "compartment_17951", "id": "reaction_10781999", "reactome": "R-SCE-6787811", "name": "HAO2 tetramer oxidises 2OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787810", "species_113535" ], "products": [ "species_6787814", "species_113575" ], "modifiers": [ [ "species_10781996", "catalyst" ] ], "additional_components": [ "P00175", "CYB2" ] }, "reaction_10761476": { "compartment": "compartment_70101", "id": "reaction_10761476", "reactome": "R-SCE-70573", "name": "argininosuccinate <=> fumarate + arginine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_34575" ], "products": [ "species_29586", "species_29468" ], "modifiers": [ [ "species_10761473", "catalyst" ] ], "additional_components": [ "P04076", "YHR018C" ] }, "reaction_10766690": { "compartment": "compartment_70101", "id": "reaction_10766690", "reactome": "R-SCE-191299", "name": "Squalene is oxidized to its epoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191269", "species_29368" ], "products": [ "species_29366", "species_191309", "species_29356" ], "modifiers": [ [ "species_10766687", "catalyst" ] ], "additional_components": [ "P32476", "YGR175C", "species_113596" ] }, "reaction_10761732": { "compartment": "compartment_5460", "id": "reaction_10761732", "reactome": "R-SCE-70997", "name": "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_70958" ], "products": [ "species_29374", "species_113536", "species_113593" ], "modifiers": [ [ "species_10761729", "catalyst" ] ], "additional_components": [ "P53598", "YOR142W", "P53312", "YGR244C" ] }, "reaction_10786830": { "compartment": "compartment_17927", "id": "reaction_10786830", "reactome": "R-SCE-8875838", "name": "SLC25A19 transports ThDP from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29480" ], "products": [ "species_8878387" ], "modifiers": [ [ "species_10786827", "catalyst" ] ], "additional_components": [ "YGR096W" ] }, "reaction_10765677": { "compartment": "compartment_70101", "id": "reaction_10765677", "reactome": "R-SCE-163764", "name": "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29878", "species_29512" ], "products": [ "species_29578", "species_29882" ], "modifiers": [ [ "species_10761886", "catalyst" ] ], "additional_components": [ "P15019", "YLR354C" ] }, "reaction_10767455": { "compartment": "compartment_17927", "id": "reaction_10767455", "reactome": "R-SCE-200424", "name": "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_201023", "species_201034" ], "products": [ "species_549207", "species_201050" ], "modifiers": [ [ "species_10767452", "catalyst" ] ], "additional_components": [ "YOR100C" ] }, "reaction_10763358": { "compartment": "compartment_70101", "id": "reaction_10763358", "reactome": "R-SCE-73797", "name": "FAICAR => IMP + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111427" ], "products": [ "species_29602", "species_29356" ], "modifiers": [ [ "species_10763355", "catalyst" ] ], "additional_components": [ "P38009", "YMR120C" ] }, "reaction_10773353": { "compartment": "compartment_70101", "id": "reaction_10773353", "reactome": "R-SCE-1497810", "name": "Uncoupled eNOS favours the formation of superoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29368" ], "products": [ "species_29366", "species_1222424" ], "modifiers": [ [ "species_10773348", "catalyst" ] ], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "species_1497857", "species_29870", "P15108", "YMR186W", "species_113596", "P11792", "YHR205W" ] }, "reaction_10788219": { "compartment": "compartment_70101", "id": "reaction_10788219", "reactome": "R-SCE-9014741", "name": "PXLP-K56-SRR dimer deaminates D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_376186" ], "products": [ "species_29382", "species_29398", "species_29356" ], "modifiers": [ [ "species_10788216", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "P36007", "YKL218C" ] }, "reaction_10786160": { "compartment": "compartment_12045", "id": "reaction_10786160", "reactome": "R-SCE-8857686", "name": "FITM1, FITM2 bind TAGs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786156", "species_549167" ], "products": [ "species_10786158" ], "modifiers": [], "additional_components": [ "Q06676", "YDR319C", "P53012", "YGL126W", "species_549167", "Q06676", "YDR319C", "P53012", "YGL126W" ] }, "reaction_10767260": { "compartment": "compartment_876", "id": "reaction_10767260", "reactome": "R-SCE-198818", "name": "SLC2A1,3 transports DeHA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198852" ], "products": [ "species_198827" ], "modifiers": [ [ "species_10767257", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10762137": { "compartment": "compartment_5460", "id": "reaction_10762137", "reactome": "R-SCE-71723", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_113532" ], "products": [ "species_113539", "species_29362", "species_113529" ], "modifiers": [ [ "species_10762134", "catalyst" ] ], "additional_components": [ "P40047", "YER073W" ] }, "reaction_10763070": { "compartment": "compartment_70101", "id": "reaction_10763070", "reactome": "R-SCE-73571", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_111628" ], "products": [ "species_29356", "species_76630" ], "modifiers": [ [ "species_10763067", "catalyst" ] ], "additional_components": [ "P07259", "YJL130C", "P03965", "YJR109C" ] }, "reaction_10769862": { "compartment": "compartment_70101", "id": "reaction_10769862", "reactome": "R-SCE-428273", "name": "SPHK1 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_29370", "species_428203" ], "modifiers": [ [ "species_10769088", "catalyst" ] ], "additional_components": [ "YLR260W" ] }, "reaction_10785507": { "compartment": "compartment_876", "id": "reaction_10785507", "reactome": "R-SCE-8850854", "name": "NTPDase1 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8870906", "species_109276" ], "products": [ "species_8870962", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785501", "catalyst" ] ], "additional_components": [ "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10788350": { "compartment": "compartment_70101", "id": "reaction_10788350", "reactome": "R-SCE-9020258", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024768" ], "products": [ "species_9024759" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "CHEBI:81565", "CHEBI:81564", "species_158417", "Q10740", "YNL045W" ] }, "reaction_10784145": { "compartment": "compartment_70101", "id": "reaction_10784145", "reactome": "R-SCE-6801342", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803257", "species_113592" ], "products": [ "species_70106", "species_29370", "species_200640", "species_29372" ], "modifiers": [ [ "species_10784142", "catalyst" ] ], "additional_components": [ "YER183C" ] }, "reaction_10777793": { "compartment": "compartment_984", "id": "reaction_10777793", "reactome": "R-SCE-5433072", "name": "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490253", "species_109276" ], "products": [ "species_210382", "species_5490235" ], "modifiers": [ [ "species_10777790", "catalyst" ] ], "additional_components": [ "CHEBI:78587", "CHEBI:78581", "CHEBI:78579", "CHEBI:78584", "Q05902", "YLR299W" ] }, "reaction_10784767": { "compartment": "compartment_70101", "id": "reaction_10784767", "reactome": "R-SCE-6809764", "name": "SBF1 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784763", "species_10773465" ], "products": [ "species_10784765" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10773553": { "compartment": "compartment_876", "id": "reaction_10773553", "reactome": "R-SCE-1675994", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10773550", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "P47147", "YJR110W", "P50942", "YNL106C" ] }, "reaction_10771041": { "compartment": "compartment_5460", "id": "reaction_10771041", "reactome": "R-SCE-482812", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_482807", "species_113581" ], "products": [ "species_482803", "species_113593" ], "modifiers": [ [ "species_10771036", "catalyst" ] ], "additional_components": [ "species_29494", "species_500739", "species_29892", "species_110644", "species_30185", "species_30187", "species_29438", "species_110614", "species_29420", "CHEBI:60471", "CHEBI:58369", "CHEBI:58595", "CHEBI:57667", "species_110096", "species_110094", "CHEBI:58593", "P36010", "YKL067W" ] }, "reaction_10767033": { "compartment": "compartment_70101", "id": "reaction_10767033", "reactome": "R-SCE-197235", "name": "NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_197220" ], "products": [ "species_197256", "species_111294" ], "modifiers": [ [ "species_10767030", "catalyst" ] ], "additional_components": [ "Q06178", "YLR328W", "P53204", "YGR010W", "species_109496" ] }, "reaction_10765667": { "compartment": "compartment_7660", "id": "reaction_10765667", "reactome": "R-SCE-163664", "name": "AMP binds to gamma subunit of AMP kinase heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765661", "species_164121" ], "products": [ "species_10765665" ], "modifiers": [], "additional_components": [ "P34164", "YGL208W", "Q04739", "YER027C", "P32578", "YDR422C", "P12904", "YGL115W", "P38845", "YHR146W", "P06782", "YDR477W", "P53885", "YNL173C", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P32578", "YDR422C", "P12904", "YGL115W", "P38845", "YHR146W", "P06782", "YDR477W", "P53885", "YNL173C" ] }, "reaction_10787120": { "compartment": "compartment_70101", "id": "reaction_10787120", "reactome": "R-SCE-8932980", "name": "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_8932979" ], "modifiers": [ [ "species_10787109", "catalyst" ] ], "additional_components": [ "YDR105C" ] }, "reaction_10764159": { "compartment": "compartment_70101", "id": "reaction_10764159", "reactome": "R-SCE-75899", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76108" ], "products": [ "species_76103", "species_29372" ], "modifiers": [ [ "species_10764152", "catalyst" ] ], "additional_components": [ "YMR165C" ] }, "reaction_10769052": { "compartment": "compartment_17951", "id": "reaction_10769052", "reactome": "R-SCE-390250", "name": "3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193514", "species_390241" ], "products": [ "species_353123", "species_390246" ], "modifiers": [ [ "species_10769049", "catalyst" ] ], "additional_components": [ "YIL160C" ] }, "reaction_10773616": { "compartment": "compartment_20699", "id": "reaction_10773616", "reactome": "R-SCE-1676204", "name": "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806230", "species_29356" ], "products": [ "species_1806217", "species_29372" ], "modifiers": [ [ "species_10773611", "catalyst" ] ], "additional_components": [ "YNL128W" ] }, "reaction_10767527": { "compartment": "compartment_70101", "id": "reaction_10767527", "reactome": "R-SCE-200711", "name": "MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29460", "species_197969" ], "products": [ "species_29370", "species_111353", "species_29372" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10771991": { "compartment": "compartment_70101", "id": "reaction_10771991", "reactome": "R-SCE-964962", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965053", "species_113592" ], "products": [ "species_29370", "species_964952" ], "modifiers": [ [ "species_10771986", "catalyst" ] ], "additional_components": [ "species_158417", "P39988", "YEL029C" ] }, "reaction_10773140": { "compartment": "compartment_70616", "id": "reaction_10773140", "reactome": "R-SCE-1482850", "name": "MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498773", "species_1524083" ], "products": [ "species_1524072", "species_1524089" ], "modifiers": [ [ "species_10773113", "catalyst" ] ], "additional_components": [] }, "reaction_10773208": { "compartment": "compartment_12045", "id": "reaction_10773208", "reactome": "R-SCE-1482962", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500603", "species_1500596" ], "products": [ "species_109395", "species_1500581" ], "modifiers": [ [ "species_10773205", "catalyst" ] ], "additional_components": [ "P17898", "YNL130C", "P22140", "YHR123W", "species_113527", "species_109496" ] }, "reaction_10784770": { "compartment": "compartment_70101", "id": "reaction_10784770", "reactome": "R-SCE-6809777", "name": "PI3P is dephosphorylated to PI by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030", "species_29356" ], "products": [ "species_426639", "species_29372" ], "modifiers": [ [ "species_10784765", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10788208": { "compartment": "compartment_70101", "id": "reaction_10788208", "reactome": "R-SCE-9014627", "name": "SDS dimers:PXLP dehydrate L-Thr to 2AA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351990" ], "products": [ "species_9014643", "species_29356" ], "modifiers": [ [ "species_10788205", "catalyst" ] ], "additional_components": [ "P25379", "YCL064C" ] }, "reaction_10769066": { "compartment": "compartment_17951", "id": "reaction_10769066", "reactome": "R-SCE-390304", "name": "acetyl-CoA + H2O => acetate + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353123", "species_141343" ], "products": [ "species_193514", "species_390305" ], "modifiers": [ [ "species_10766854", "catalyst" ] ], "additional_components": [ "YJR019C" ] }, "reaction_10766152": { "compartment": "compartment_5460", "id": "reaction_10766152", "reactome": "R-SCE-169260", "name": "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766147", "species_31649" ], "products": [ "species_10766149", "species_113596" ], "modifiers": [ [ "species_10766147", "catalyst" ] ], "additional_components": [ "species_76577", "Q12480", "YPR004C", "P42940", "YGR207C", "species_113596", "species_76577", "species_31649", "Q12480", "YPR004C", "P42940", "YGR207C", "species_76577", "Q12480", "YPR004C", "P42940", "YGR207C", "species_113596" ] }, "reaction_10773039": { "compartment": "compartment_12045", "id": "reaction_10773039", "reactome": "R-SCE-1482636", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498724", "species_1500578" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10772920", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10772026": { "compartment": "compartment_70101", "id": "reaction_10772026", "reactome": "R-SCE-977333", "name": "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_977329" ], "products": [ "species_936706", "species_29406" ], "modifiers": [ [ "species_10772023", "catalyst" ] ], "additional_components": [ "P33330", "YOR184W" ] }, "reaction_10766425": { "compartment": "compartment_70101", "id": "reaction_10766425", "reactome": "R-SCE-177784", "name": "ribose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10761876", "catalyst" ] ], "additional_components": [ "YOR095C" ] }, "reaction_10762017": { "compartment": "compartment_70101", "id": "reaction_10762017", "reactome": "R-SCE-71590", "name": "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762014", "species_29372" ], "products": [ "species_10761967", "species_29548" ], "modifiers": [ [ "species_10762009", "catalyst" ] ], "additional_components": [ "P47011", "YJL137C", "species_113527", "P47011", "YJL137C", "species_113527", "P06738", "YPR160W" ] }, "reaction_10773054": { "compartment": "compartment_12045", "id": "reaction_10773054", "reactome": "R-SCE-1482691", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498722", "species_1500578" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10772920", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10774286": { "compartment": "compartment_70101", "id": "reaction_10774286", "reactome": "R-SCE-2393939", "name": "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1131972" ], "products": [ "species_73578", "species_76577" ], "modifiers": [ [ "species_10774283", "catalyst" ] ], "additional_components": [ "Q01976", "YBR111C", "species_109496" ] }, "reaction_10769044": { "compartment": "compartment_17951", "id": "reaction_10769044", "reactome": "R-SCE-389995", "name": "3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192307", "species_389982" ], "products": [ "species_389996", "species_193465", "species_192305" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10763073": { "compartment": "compartment_70101", "id": "reaction_10763073", "reactome": "R-SCE-73573", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29448", "species_111647" ], "products": [ "species_70106", "species_29372", "species_111628" ], "modifiers": [ [ "species_10763067", "catalyst" ] ], "additional_components": [ "P07259", "YJL130C", "P03965", "YJR109C" ] }, "reaction_10782024": { "compartment": "compartment_5460", "id": "reaction_10782024", "reactome": "R-SCE-6788798", "name": "AK4 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788802", "species_113593" ], "products": [ "species_113581", "species_6788801" ], "modifiers": [ [ "species_10782021", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "YER170W" ] }, "reaction_10773472": { "compartment": "compartment_172574", "id": "reaction_10773472", "reactome": "R-SCE-1675795", "name": "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806198", "species_29356" ], "products": [ "species_1806195", "species_29372" ], "modifiers": [ [ "species_10773463", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10769935": { "compartment": "compartment_70101", "id": "reaction_10769935", "reactome": "R-SCE-428701", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10769886", "catalyst" ] ], "additional_components": [ "P47013", "YJL134W", "P23501", "YKR053C" ] }, "reaction_10768244": { "compartment": "compartment_876", "id": "reaction_10768244", "reactome": "R-SCE-266046", "name": "GGT1, 5 dimers hydrolyse LTC4 to LTD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266013", "species_109276" ], "products": [ "species_210382", "species_266074" ], "modifiers": [ [ "species_10768241", "catalyst" ] ], "additional_components": [ "Q05902", "YLR299W" ] }, "reaction_10776221": { "compartment": "compartment_70101", "id": "reaction_10776221", "reactome": "R-SCE-3780994", "name": "GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10776213" ], "products": [ "species_10776218", "species_109402" ], "modifiers": [ [ "species_10776213", "catalyst" ] ], "additional_components": [ "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10771993": { "compartment": "compartment_70101", "id": "reaction_10771993", "reactome": "R-SCE-964970", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965131", "species_113592" ], "products": [ "species_29370", "species_29390" ], "modifiers": [ [ "species_10771986", "catalyst" ] ], "additional_components": [ "species_158417", "P39988", "YEL029C" ] }, "reaction_10773571": { "compartment": "compartment_20699", "id": "reaction_10773571", "reactome": "R-SCE-1676114", "name": "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806159", "species_29356" ], "products": [ "species_1524146", "species_29372" ], "modifiers": [ [ "species_10773568", "catalyst" ] ], "additional_components": [ "YKL212W" ] }, "reaction_10767728": { "compartment": "compartment_70101", "id": "reaction_10767728", "reactome": "R-SCE-203611", "name": "N-myristoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_184174", "species_10767726" ], "products": [ "species_10767644" ], "modifiers": [], "additional_components": [ "YHR042W", "YHR042W" ] }, "reaction_10773396": { "compartment": "compartment_70101", "id": "reaction_10773396", "reactome": "R-SCE-1614583", "name": "PXLP-K212-CTH cleaves L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614518", "species_29356" ], "products": [ "species_29382", "species_936714", "species_111707" ], "modifiers": [ [ "species_10773390", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10761549": { "compartment": "compartment_70101", "id": "reaction_10761549", "reactome": "R-SCE-70634", "name": "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498", "species_113567" ], "products": [ "species_113585", "species_29968" ], "modifiers": [ [ "species_10761546", "catalyst" ] ], "additional_components": [ "Q12375", "YOR130C", "P38087", "YBR104W", "P32331", "YPR058W" ] }, "reaction_10766880": { "compartment": "compartment_876", "id": "reaction_10766880", "reactome": "R-SCE-194153", "name": "ABCC3 transports bile salts from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_194156" ], "products": [ "species_29370", "species_192483", "species_29372" ], "modifiers": [ [ "species_10766877", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "CHEBI:16755", "species_193451", "CHEBI:16525", "CHEBI:28865", "CHEBI:36274", "CHEBI:17687", "CHEBI:16755", "species_193451", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274", "YGR281W" ] }, "reaction_10764658": { "compartment": "compartment_70101", "id": "reaction_10764658", "reactome": "R-SCE-110144", "name": "ADP + ADP <=> AMP + ATP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370" ], "products": [ "species_113592", "species_76577" ], "modifiers": [ [ "species_10764655", "catalyst" ] ], "additional_components": [ "YDR226W" ] }, "reaction_10785452": { "compartment": "compartment_12045", "id": "reaction_10785452", "reactome": "R-SCE-8848582", "name": "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848577", "species_200993" ], "products": [ "species_76194", "species_8848499" ], "modifiers": [ [ "species_10781638", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10766928": { "compartment": "compartment_70101", "id": "reaction_10766928", "reactome": "R-SCE-196350", "name": "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_29360" ], "products": [ "species_70106", "species_73473", "species_196344" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10761446": { "compartment": "compartment_5460", "id": "reaction_10761446", "reactome": "R-SCE-70555", "name": "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113561", "species_29896", "species_113593" ], "products": [ "species_29676", "species_113548", "species_113581" ], "modifiers": [ [ "species_10761443", "catalyst" ], [ "species_30471", "catalyst" ] ], "additional_components": [ "YJL130C" ] }, "reaction_10764500": { "compartment": "compartment_70101", "id": "reaction_10764500", "reactome": "R-SCE-109624", "name": "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500173", "species_113592" ], "products": [ "species_29370", "species_500088" ], "modifiers": [ [ "species_10764497", "catalyst" ] ], "additional_components": [ "species_83909", "CHEBI:17256", "species_76577", "species_109386", "P47143", "YJR105W", "species_109496" ] }, "reaction_10781620": { "compartment": "compartment_876", "id": "reaction_10781620", "reactome": "R-SCE-5696080", "name": "ALDH3B1 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_29356", "species_428663" ], "products": [ "species_70106", "species_73473", "species_3632881" ], "modifiers": [ [ "species_10781617", "catalyst" ] ], "additional_components": [ "YMR110C" ] }, "reaction_10773589": { "compartment": "compartment_876", "id": "reaction_10773589", "reactome": "R-SCE-1676145", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10773586", "catalyst" ] ], "additional_components": [ "P38994", "YDR208W" ] }, "reaction_10761466": { "compartment": "compartment_70101", "id": "reaction_10761466", "reactome": "R-SCE-70569", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29356" ], "products": [ "species_29498", "species_29514" ], "modifiers": [ [ "species_10761463", "catalyst" ] ], "additional_components": [ "P00812", "YPL111W", "species_113527" ] }, "reaction_10785455": { "compartment": "compartment_12045", "id": "reaction_10785455", "reactome": "R-SCE-8848585", "name": "AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30209", "species_200993" ], "products": [ "species_76194", "species_2534407" ], "modifiers": [ [ "species_10781638", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10766738": { "compartment": "compartment_70101", "id": "reaction_10766738", "reactome": "R-SCE-191380", "name": "Mevalonate is phosphorylated to mevalonate-5-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191424" ], "products": [ "species_29370", "species_191296" ], "modifiers": [ [ "species_10766735", "catalyst" ] ], "additional_components": [ "P07277", "YMR208W" ] }, "reaction_10772862": { "compartment": "compartment_5460", "id": "reaction_10772862", "reactome": "R-SCE-1362408", "name": "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772851", "species_10772838", "species_379721" ], "products": [ "species_10772853", "species_10772859", "species_379697" ], "modifiers": [ [ "species_10772838", "catalyst" ], [ "species_10772851", "catalyst" ] ], "additional_components": [ "CHEBI:33738", "Q12184", "YPL252C", "P25374", "YCL017C", "Q6Q560", "YER048W-A", "species_111793", "Q07540", "YFH1", "Q03020", "YPL135W", "P25374", "YCL017C", "Q6Q560", "YER048W-A", "CHEBI:33739", "Q07540", "YFH1", "Q03020", "YPL135W", "CHEBI:33737", "Q12184", "YPL252C", "P25374", "YCL017C", "Q6Q560", "YER048W-A", "species_111793", "Q07540", "YFH1", "Q03020", "YPL135W", "CHEBI:33738", "Q12184", "YPL252C" ] }, "reaction_10766930": { "compartment": "compartment_70101", "id": "reaction_10766930", "reactome": "R-SCE-196372", "name": "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193124", "species_29360" ], "products": [ "species_70106", "species_73473", "species_196366" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10774126": { "compartment": "compartment_17951", "id": "reaction_10774126", "reactome": "R-SCE-2066788", "name": "Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2066762", "species_193514" ], "products": [ "species_353123", "species_2066765" ], "modifiers": [ [ "species_10769049", "catalyst" ] ], "additional_components": [ "YIL160C" ] }, "reaction_10761825": { "compartment": "compartment_70101", "id": "reaction_10761825", "reactome": "R-SCE-71261", "name": "BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31369", "species_29368", "species_29406" ], "products": [ "species_113528", "species_30235", "species_29434" ], "modifiers": [ [ "species_10761822", "catalyst" ] ], "additional_components": [ "species_111793", "species_198816", "P23180", "YHL021C" ] }, "reaction_10761669": { "compartment": "compartment_5460", "id": "reaction_10761669", "reactome": "R-SCE-70975", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113587", "species_113559" ], "products": [ "species_29374", "species_29654" ], "modifiers": [ [ "species_10761666", "catalyst" ] ], "additional_components": [ "P00890", "CIT1" ] }, "reaction_10788352": { "compartment": "compartment_70101", "id": "reaction_10788352", "reactome": "R-SCE-9020270", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024577" ], "products": [ "species_9024570" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "CHEBI:138616", "CHEBI:138615", "species_158417", "Q10740", "YNL045W" ] }, "reaction_10764963": { "compartment": "compartment_70101", "id": "reaction_10764963", "reactome": "R-SCE-112034", "name": "PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500244", "species_83956" ], "products": [ "species_500245", "species_29372" ], "modifiers": [ [ "species_10763557", "catalyst" ] ], "additional_components": [ "species_112016", "CHEBI:58576", "CHEBI:17172", "CHEBI:16750", "Q05788", "YLR209C" ] }, "reaction_10778389": { "compartment": "compartment_17963", "id": "reaction_10778389", "reactome": "R-SCE-5653873", "name": "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70113" ], "products": [ "species_964746" ], "modifiers": [ [ "species_10778386", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10773283": { "compartment": "compartment_12045", "id": "reaction_10773283", "reactome": "R-SCE-1483121", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_426755" ], "products": [ "species_426955", "species_111294" ], "modifiers": [ [ "species_10773280", "catalyst" ] ], "additional_components": [ "P38221", "YBR029C", "species_109496" ] }, "reaction_10786171": { "compartment": "compartment_70101", "id": "reaction_10786171", "reactome": "R-SCE-8862380", "name": "HSD17B13 binds lipid droplets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866926", "species_10781197" ], "products": [ "species_10786169" ], "modifiers": [], "additional_components": [ "species_163579", "CHEBI:16247", "species_549167", "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C", "species_163579", "CHEBI:16247", "species_549167", "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C" ] }, "reaction_10766710": { "compartment": "compartment_70101", "id": "reaction_10766710", "reactome": "R-SCE-191323", "name": "HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191293", "species_29356", "species_76183" ], "products": [ "species_70106", "species_76194", "species_191374" ], "modifiers": [ [ "species_10766707", "catalyst" ] ], "additional_components": [ "YML126C" ] }, "reaction_10761158": { "compartment": "compartment_70101", "id": "reaction_10761158", "reactome": "R-SCE-70369", "name": "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29452" ], "products": [ "species_29410" ], "modifiers": [ [ "species_10761155", "catalyst" ] ], "additional_components": [ "P04397", "YBR019C", "species_113526" ] }, "reaction_10773537": { "compartment": "compartment_20699", "id": "reaction_10773537", "reactome": "R-SCE-1675961", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806159" ], "modifiers": [ [ "species_10773532", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "species_113527" ] }, "reaction_10781258": { "compartment": "compartment_12045", "id": "reaction_10781258", "reactome": "R-SCE-5693761", "name": "FA2H hydroxylates CERA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_428256" ], "products": [ "species_5693768", "species_29356" ], "modifiers": [ [ "species_10781255", "catalyst" ] ], "additional_components": [ "YMR272C" ] }, "reaction_10786994": { "compartment": "compartment_984", "id": "reaction_10786994", "reactome": "R-SCE-8878787", "name": "ALPI dimer hydrolyses phosphate monoesters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8878780", "species_109276" ], "products": [ "species_109277", "species_8878776" ], "modifiers": [ [ "species_10786991", "catalyst" ] ], "additional_components": [ "species_158417", "P11491", "YDR481C", "species_74016" ] }, "reaction_10785449": { "compartment": "compartment_12045", "id": "reaction_10785449", "reactome": "R-SCE-8848580", "name": "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_76194", "species_1500594" ], "modifiers": [ [ "species_10785444", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10784665": { "compartment": "compartment_5460", "id": "reaction_10784665", "reactome": "R-SCE-6808487", "name": "ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6808499", "species_113563", "species_113521" ], "products": [ "species_113600", "species_200679", "species_29376", "species_113529" ], "modifiers": [ [ "species_10784662", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10764630": { "compartment": "compartment_70101", "id": "reaction_10764630", "reactome": "R-SCE-109903", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500759", "species_113592" ], "products": [ "species_29370", "species_500761" ], "modifiers": [ [ "species_10764627", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:16704", "species_109395", "species_109402", "Q12084", "YDR020C" ] }, "reaction_10773579": { "compartment": "compartment_20699", "id": "reaction_10773579", "reactome": "R-SCE-1676133", "name": "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806217" ], "products": [ "species_1524146", "species_29372" ], "modifiers": [ [ "species_10773568", "catalyst" ] ], "additional_components": [ "YKL212W" ] }, "reaction_10761634": { "compartment": "compartment_5460", "id": "reaction_10761634", "reactome": "R-SCE-70938", "name": "lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113600", "species_29444", "species_113529" ], "products": [ "species_113563", "species_113521", "species_30176" ], "modifiers": [ [ "species_10761631", "catalyst" ] ], "additional_components": [ "P38999", "YNR050C" ] }, "reaction_10761228": { "compartment": "compartment_70101", "id": "reaction_10761228", "reactome": "R-SCE-70420", "name": "HK1,2,3,GCK phosphorylate Glc to form G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_70113" ], "products": [ "species_70106", "species_29370", "species_30537" ], "modifiers": [ [ "species_10761225", "catalyst" ] ], "additional_components": [ "Q04409", "YDR516C", "Q06204", "YLR446W", "P04806", "YFR053C", "P17709", "YCL040W", "P04807", "YGL253W" ] }, "reaction_10788344": { "compartment": "compartment_70101", "id": "reaction_10788344", "reactome": "R-SCE-9020252", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024602", "species_29356" ], "products": [ "species_9024574" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "CHEBI:138179", "CHEBI:138614", "species_158417", "Q10740", "YNL045W" ] }, "reaction_10766553": { "compartment": "compartment_70101", "id": "reaction_10766553", "reactome": "R-SCE-189425", "name": "UROD decarboxylates URO3 to COPRO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189407" ], "products": [ "species_113528", "species_189455" ], "modifiers": [ [ "species_10766550", "catalyst" ] ], "additional_components": [ "P32347", "YDR047W" ] }, "reaction_10766603": { "compartment": "compartment_70101", "id": "reaction_10766603", "reactome": "R-SCE-190141", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766560", "species_190173" ], "products": [ "species_29426", "species_10766601" ], "modifiers": [], "additional_components": [ "species_158417", "P05373", "YGL040C", "species_158417", "species_190173", "P05373", "YGL040C" ] }, "reaction_10761871": { "compartment": "compartment_70101", "id": "reaction_10761871", "reactome": "R-SCE-71303", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29732" ], "products": [ "species_29790" ], "modifiers": [ [ "species_10761868", "catalyst" ] ], "additional_components": [ "P46969", "YJL121C", "species_111793" ] }, "reaction_10766563": { "compartment": "compartment_70101", "id": "reaction_10766563", "reactome": "R-SCE-189439", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189489" ], "products": [ "species_70106", "species_189464", "species_29356" ], "modifiers": [ [ "species_10766560", "catalyst" ] ], "additional_components": [ "species_158417", "P05373", "YGL040C" ] }, "reaction_10766915": { "compartment": "compartment_70101", "id": "reaction_10766915", "reactome": "R-SCE-194718", "name": "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_194657" ], "products": [ "species_73473", "species_70106", "species_194661", "species_113528" ], "modifiers": [ [ "species_10766887", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10774123": { "compartment": "compartment_17951", "id": "reaction_10774123", "reactome": "R-SCE-2066780", "name": "Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2066766" ], "products": [ "species_2066762" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10784308": { "compartment": "compartment_70101", "id": "reaction_10784308", "reactome": "R-SCE-6806877", "name": "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8866401" ], "products": [ "species_29370", "species_6806881" ], "modifiers": [ [ "species_10784305", "catalyst" ] ], "additional_components": [ "P36010", "YKL067W" ] }, "reaction_10784740": { "compartment": "compartment_70101", "id": "reaction_10784740", "reactome": "R-SCE-6809309", "name": "MTMR6 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773548", "species_10784724" ], "products": [ "species_10784738" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10763122": { "compartment": "compartment_70101", "id": "reaction_10763122", "reactome": "R-SCE-73596", "name": "dCMP + H2O => dUMP + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_109378", "species_29356" ], "products": [ "species_109382", "species_31633" ], "modifiers": [ [ "species_10763119", "catalyst" ] ], "additional_components": [ "P06773", "YHR144C" ] }, "reaction_10769900": { "compartment": "compartment_70101", "id": "reaction_10769900", "reactome": "R-SCE-428681", "name": "sphinganine 1-phosphate => phosphoethanolamine + hexadecanal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428275" ], "products": [ "species_428686", "species_428663" ], "modifiers": [ [ "species_10769895", "catalyst" ] ], "additional_components": [ "YDR294C" ] }, "reaction_10770866": { "compartment": "compartment_5460", "id": "reaction_10770866", "reactome": "R-SCE-450975", "name": "isocitrate <=> citrate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29938" ], "products": [ "species_29654" ], "modifiers": [ [ "species_10761657", "catalyst" ] ], "additional_components": [] }, "reaction_10766533": { "compartment": "compartment_17927", "id": "reaction_10766533", "reactome": "R-SCE-189421", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189411", "species_189461" ], "products": [ "species_189481", "species_189480", "species_189478" ], "modifiers": [ [ "species_10766530", "catalyst" ] ], "additional_components": [ "P11353", "YDR044W" ] }, "reaction_10763393": { "compartment": "compartment_70101", "id": "reaction_10763393", "reactome": "R-SCE-73814", "name": "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_113592", "species_111292" ], "products": [ "species_70106", "species_29370", "species_111338", "species_29372" ], "modifiers": [ [ "species_10763376", "catalyst" ] ], "additional_components": [ "YGL234W" ] }, "reaction_10771060": { "compartment": "compartment_70101", "id": "reaction_10771060", "reactome": "R-SCE-504054", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29494", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_110614", "species_29372" ], "modifiers": [ [ "species_10771057", "catalyst" ] ], "additional_components": [ "P28274", "YBL039C", "P38627", "YJR103W" ] }, "reaction_10784318": { "compartment": "compartment_5460", "id": "reaction_10784318", "reactome": "R-SCE-6806966", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807473" ], "products": [ "species_6807477" ], "modifiers": [ [ "species_10784315", "catalyst" ] ], "additional_components": [ "P40165", "YNL200C" ] }, "reaction_10778609": { "compartment": "compartment_70101", "id": "reaction_10778609", "reactome": "R-SCE-5662471", "name": "SORD tetramer oxidizes xylitol to D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5660033", "species_29360" ], "products": [ "species_70106", "species_73473", "species_5661281" ], "modifiers": [ [ "species_10778317", "catalyst" ] ], "additional_components": [ "Q07993", "YLR070C", "species_158417", "Q07786", "YDL246C", "P35497", "YJR159W" ] }, "reaction_10773555": { "compartment": "compartment_172574", "id": "reaction_10773555", "reactome": "R-SCE-1676024", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806195" ], "products": [ "species_29370", "species_1806198" ], "modifiers": [ [ "species_10773532", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "species_113527" ] }, "reaction_10773582": { "compartment": "compartment_876", "id": "reaction_10773582", "reactome": "R-SCE-1676134", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_1806224" ], "modifiers": [ [ "species_10773418", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10775627": { "compartment": "compartment_70101", "id": "reaction_10775627", "reactome": "R-SCE-3323111", "name": "Cytoslic carboxylases translocate to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774825" ], "products": [ "species_10774951" ], "modifiers": [], "additional_components": [ "P11154", "YGL062W", "species_113527", "P11154", "YGL062W", "species_113527" ] }, "reaction_10772944": { "compartment": "compartment_12045", "id": "reaction_10772944", "reactome": "R-SCE-1482543", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_29356" ], "products": [ "species_76116", "species_1500593" ], "modifiers": [ [ "species_10772941", "catalyst" ] ], "additional_components": [ "P28321", "YKL094W" ] }, "reaction_10766885": { "compartment": "compartment_70101", "id": "reaction_10766885", "reactome": "R-SCE-194641", "name": "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194644", "species_29368" ], "products": [ "species_29366", "species_194735", "species_29356" ], "modifiers": [ [ "species_10766882", "catalyst" ] ], "additional_components": [ "YGR060W" ] }, "reaction_10766847": { "compartment": "compartment_70101", "id": "reaction_10766847", "reactome": "R-SCE-193052", "name": "Pregn-5-ene-3,20-dione isomerizes to progesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196344" ], "products": [ "species_193055" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10761580": { "compartment": "compartment_5460", "id": "reaction_10761580", "reactome": "R-SCE-70670", "name": "PRODH oxidises L-Pro to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_379717", "species_113597" ], "products": [ "species_164934", "species_113529", "species_113590" ], "modifiers": [ [ "species_10761577", "catalyst" ] ], "additional_components": [ "YLR142W" ] }, "reaction_10768933": { "compartment": "compartment_17951", "id": "reaction_10768933", "reactome": "R-SCE-389611", "name": "2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389594" ], "products": [ "species_389578", "species_389636" ], "modifiers": [ [ "species_10768930", "catalyst" ] ], "additional_components": [ "species_29480", "species_109496", "P39994", "YEL020C" ] }, "reaction_10772867": { "compartment": "compartment_5460", "id": "reaction_10772867", "reactome": "R-SCE-1362416", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772865", "species_113531" ], "products": [ "species_10772838" ], "modifiers": [], "additional_components": [ "P25374", "YCL017C", "Q6Q560", "YER048W-A", "Q07540", "YFH1", "Q03020", "YPL135W", "P25374", "YCL017C", "Q6Q560", "YER048W-A", "species_111793", "Q07540", "YFH1", "Q03020", "YPL135W" ] }, "reaction_10767499": { "compartment": "compartment_70101", "id": "reaction_10767499", "reactome": "R-SCE-200661", "name": "MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111353" ], "products": [ "species_200640", "species_29356" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10774100": { "compartment": "compartment_12045", "id": "reaction_10774100", "reactome": "R-SCE-2046093", "name": "Translocation of tetracosapentaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046050", "species_211579" ], "products": [ "species_2046055", "species_5228339", "species_211606" ], "modifiers": [ [ "species_10768821", "catalyst" ] ], "additional_components": [ "YPL147W" ] }, "reaction_10787692": { "compartment": "compartment_70101", "id": "reaction_10787692", "reactome": "R-SCE-8955760", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800", "species_30537" ], "products": [ "species_70106", "species_29728", "species_8955759" ], "modifiers": [ [ "species_10761123", "catalyst" ] ], "additional_components": [ "Q03262", "YMR278W", "species_109496" ] }, "reaction_10784147": { "compartment": "compartment_5460", "id": "reaction_10784147", "reactome": "R-SCE-6801456", "name": "MTHFD1L transforms 10-formyl-THF to HCOOH and THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5389850", "species_113548", "species_113581" ], "products": [ "species_200671", "species_6801451", "species_113593" ], "modifiers": [ [ "species_10781645", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10770911": { "compartment": "compartment_5460", "id": "reaction_10770911", "reactome": "R-SCE-452036", "name": "arginine + H2O => ornithine + urea [ARG2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_374064" ], "products": [ "species_113585", "species_374061" ], "modifiers": [ [ "species_10770908", "catalyst" ] ], "additional_components": [ "P00812", "YPL111W", "species_113527" ] }, "reaction_10766849": { "compartment": "compartment_70101", "id": "reaction_10766849", "reactome": "R-SCE-193073", "name": "HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_176626" ], "products": [ "species_70106", "species_73473", "species_193079" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10769061": { "compartment": "compartment_17951", "id": "reaction_10769061", "reactome": "R-SCE-390284", "name": "propionyl-CoA + carnitine => propionylcarnitine + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390294", "species_192314" ], "products": [ "species_193514", "species_390274" ], "modifiers": [ [ "species_10769058", "catalyst" ] ], "additional_components": [ "YML042W" ] }, "reaction_10763317": { "compartment": "compartment_70101", "id": "reaction_10763317", "reactome": "R-SCE-73792", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111584", "species_29472", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29404", "species_111294", "species_76577", "species_113578" ], "modifiers": [ [ "species_10763314", "catalyst" ] ], "additional_components": [ "YMR217W" ] }, "reaction_10781076": { "compartment": "compartment_70101", "id": "reaction_10781076", "reactome": "R-SCE-5692237", "name": "ADH5 oxidises S-HMGSH to S-FGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5692221", "species_29360" ], "products": [ "species_73473", "species_70106", "species_5692249" ], "modifiers": [ [ "species_10781073", "catalyst" ] ], "additional_components": [ "species_158417", "P32771", "YDL168W" ] }, "reaction_10767529": { "compartment": "compartment_70101", "id": "reaction_10767529", "reactome": "R-SCE-200718", "name": "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200640" ], "products": [ "species_29366", "species_200739" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10774098": { "compartment": "compartment_17957", "id": "reaction_10774098", "reactome": "R-SCE-2046087", "name": "Translocation of tetracosahexaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046054", "species_211579" ], "products": [ "species_2046047", "species_211606", "species_426639" ], "modifiers": [ [ "species_10768821", "catalyst" ] ], "additional_components": [ "YPL147W" ] }, "reaction_10767537": { "compartment": "compartment_70101", "id": "reaction_10767537", "reactome": "R-SCE-200740", "name": "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200640", "species_29356" ], "products": [ "species_111353" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10769032": { "compartment": "compartment_17951", "id": "reaction_10769032", "reactome": "R-SCE-389889", "name": "ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389893", "species_113535" ], "products": [ "species_389894", "species_113575" ], "modifiers": [ [ "species_10769029", "catalyst" ] ], "additional_components": [ "P13711", "YGL205W", "species_113596" ] }, "reaction_10766890": { "compartment": "compartment_70101", "id": "reaction_10766890", "reactome": "R-SCE-194642", "name": "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194735", "species_29360" ], "products": [ "species_70106", "species_73473", "species_113528", "species_194667" ], "modifiers": [ [ "species_10766887", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10764323": { "compartment": "compartment_70101", "id": "reaction_10764323", "reactome": "R-SCE-76590", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76577", "species_29356" ], "products": [ "species_29602", "species_31633" ], "modifiers": [ [ "species_10764320", "catalyst" ] ], "additional_components": [ "P38150", "YJL070C", "P15274", "YML035C", "P40361", "YJL070C" ] }, "reaction_10761802": { "compartment": "compartment_70101", "id": "reaction_10761802", "reactome": "R-SCE-71218", "name": "3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_30487" ], "products": [ "species_36027" ], "modifiers": [ [ "species_10761799", "catalyst" ] ], "additional_components": [ "P47096", "YJR025C", "species_111793" ] }, "reaction_10765675": { "compartment": "compartment_7660", "id": "reaction_10765675", "reactome": "R-SCE-163748", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10764091" ], "modifiers": [], "additional_components": [ "YDL052C" ] }, "reaction_10779627": { "compartment": "compartment_12045", "id": "reaction_10779627", "reactome": "R-SCE-5689000", "name": "AADAC deacetylates PHEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5689006", "species_29356" ], "products": [ "species_5688995", "species_5689001" ], "modifiers": [ [ "species_10779624", "catalyst" ] ], "additional_components": [ "YGR263C" ] }, "reaction_10781992": { "compartment": "compartment_70101", "id": "reaction_10781992", "reactome": "R-SCE-6787329", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_112016" ], "products": [ "species_73578" ], "modifiers": [ [ "species_10761119", "catalyst" ] ], "additional_components": [ "Q03262", "YMR278W", "species_109496" ] }, "reaction_10763550": { "compartment": "compartment_70101", "id": "reaction_10763550", "reactome": "R-SCE-74213", "name": "APRT catalyzes the conversion of adenine to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_83951" ], "products": [ "species_111294", "species_76577" ], "modifiers": [ [ "species_10763547", "catalyst" ] ], "additional_components": [ "P49435", "YML022W" ] }, "reaction_10766581": { "compartment": "compartment_5460", "id": "reaction_10766581", "reactome": "R-SCE-189442", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70958", "species_159549", "species_113529" ], "products": [ "species_29374", "species_189466", "species_29376" ], "modifiers": [ [ "species_10766578", "catalyst" ], [ "species_189444", "inhibitor" ] ], "additional_components": [ "P09950", "YDR232W" ] }, "reaction_10787970": { "compartment": "compartment_70101", "id": "reaction_10787970", "reactome": "R-SCE-9012374", "name": "VDAC1 transports PYR from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398" ], "products": [ "species_9012375" ], "modifiers": [ [ "species_10777036", "catalyst" ] ], "additional_components": [ "P04840", "POR1", "P40478", "YIL114C" ] }, "reaction_10780397": { "compartment": "compartment_17951", "id": "reaction_10780397", "reactome": "R-SCE-5690042", "name": "Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_5690520" ], "products": [ "species_193514", "species_5690539" ], "modifiers": [ [ "species_10766854", "catalyst" ] ], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "species_382577", "CHEBI:59554", "YJR019C" ] }, "reaction_10761921": { "compartment": "compartment_5460", "id": "reaction_10761921", "reactome": "R-SCE-71401", "name": "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113594", "species_113526" ], "products": [ "species_29376", "species_70958", "species_29362" ], "modifiers": [ [ "species_10761760", "catalyst" ] ], "additional_components": [ "species_29480", "P20967", "YIL125W", "CHEBI:17460", "P09624", "YFL018C", "species_113596", "P19262", "YDR148C" ] }, "reaction_10773344": { "compartment": "compartment_70101", "id": "reaction_10773344", "reactome": "R-SCE-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1498751" ], "products": [ "species_29370", "species_428686" ], "modifiers": [ [ "species_10773341", "catalyst" ] ], "additional_components": [ "P20485", "YLR133W", "Q03764", "YDR147W" ] }, "reaction_10769039": { "compartment": "compartment_17951", "id": "reaction_10769039", "reactome": "R-SCE-389891", "name": "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389893", "species_113535" ], "products": [ "species_389894", "species_113575" ], "modifiers": [ [ "species_10769036", "catalyst" ] ], "additional_components": [ "P13711", "YGL205W", "species_113596" ] }, "reaction_10769019": { "compartment": "compartment_17951", "id": "reaction_10769019", "reactome": "R-SCE-389842", "name": "HAO1 tetramer oxidizes glycolate to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389822", "species_113535" ], "products": [ "species_389678", "species_113575" ], "modifiers": [ [ "species_10769016", "catalyst" ] ], "additional_components": [ "species_73524", "P00175", "CYB2" ] }, "reaction_10785562": { "compartment": "compartment_984", "id": "reaction_10785562", "reactome": "R-SCE-8851356", "name": "NTPDase5 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936165", "species_109276" ], "products": [ "species_109277", "species_351626", "species_8851369" ], "modifiers": [ [ "species_10785559", "catalyst" ] ], "additional_components": [ "species_29420", "species_29370", "species_110094", "species_110096", "species_109395", "species_76577", "species_109402", "species_113578", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10773047": { "compartment": "compartment_12045", "id": "reaction_10773047", "reactome": "R-SCE-1482667", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498738", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10773037", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10774299": { "compartment": "compartment_5460", "id": "reaction_10774299", "reactome": "R-SCE-2395517", "name": "NADPH transfers electrons to FDXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_10774295", "species_113529" ], "products": [ "species_10774293", "species_113563" ], "modifiers": [], "additional_components": [ "P48360", "YDR376W", "species_113596", "P48360", "YDR376W", "species_31649" ] }, "reaction_10761456": { "compartment": "compartment_5460", "id": "reaction_10761456", "reactome": "R-SCE-70560", "name": "carbamoyl phosphate + ornithine => citrulline + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29676", "species_113585" ], "products": [ "species_113548", "species_113567" ], "modifiers": [ [ "species_10761453", "catalyst" ] ], "additional_components": [ "P05150", "YJL088W" ] }, "reaction_10763572": { "compartment": "compartment_70101", "id": "reaction_10763572", "reactome": "R-SCE-74255", "name": "Guanine + H2O => Xanthine + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29356", "species_83956" ], "products": [ "species_30064", "species_31633" ], "modifiers": [ [ "species_10763569", "catalyst" ] ], "additional_components": [ "species_158417", "Q07729", "YDL238C" ] }, "reaction_10773257": { "compartment": "compartment_70616", "id": "reaction_10773257", "reactome": "R-SCE-1483063", "name": "PG and CDP-DAG are converted to CL by CRLS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_1524064" ], "products": [ "species_1524067", "species_1524072" ], "modifiers": [ [ "species_10772962", "catalyst" ] ], "additional_components": [ "YDL142C" ] }, "reaction_10785439": { "compartment": "compartment_17957", "id": "reaction_10785439", "reactome": "R-SCE-8848246", "name": "DBI, ACBD7 bind MCFA-CoA and LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848288", "species_10785433" ], "products": [ "species_10785437" ], "modifiers": [], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "YGR037C", "CHEBI:33184", "CHEBI:61907", "P31787", "YGR037C" ] }, "reaction_10765739": { "compartment": "compartment_70616", "id": "reaction_10765739", "reactome": "R-SCE-164651", "name": "Electron transfer from ubiquinol to cytochrome c of complex III", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76633", "species_10765569", "species_113529", "species_73663" ], "products": [ "species_76633", "species_10765567", "species_163953", "species_73663" ], "modifiers": [ [ "species_10765736", "catalyst" ] ], "additional_components": [ "P00045", "YEL039C", "P00044", "YJR048W", "CHEBI:38574", "P00045", "YEL039C", "P00044", "YJR048W", "CHEBI:38573", "P11914", "MAS2", "P00128", "YDR529C", "P10507", "MAS1", "P07256", "YBL045C", "P08067", "YEL024W", "P00163", "Q0105", "P07143", "CYT1", "P22289", "YGR183C", "P00127", "YFR033C", "P08525", "YJL166W" ] }, "reaction_10766892": { "compartment": "compartment_70101", "id": "reaction_10766892", "reactome": "R-SCE-194669", "name": "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194723", "species_29368" ], "products": [ "species_29366", "species_29356", "species_194657" ], "modifiers": [ [ "species_10766882", "catalyst" ] ], "additional_components": [ "YGR060W" ] }, "reaction_10789271": { "compartment": "compartment_70101", "id": "reaction_10789271", "reactome": "R-SCE-9717834", "name": "GGPS1 hexamer transfers IPPP to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191324" ], "products": [ "species_191409", "species_111294" ], "modifiers": [ [ "species_10789265", "catalyst" ] ], "additional_components": [ "Q12051", "YPL069C", "species_109496" ] }, "reaction_10775602": { "compartment": "compartment_70101", "id": "reaction_10775602", "reactome": "R-SCE-3322019", "name": "Autoglucosylation of GYG2 complexed with GYS2-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775597" ], "products": [ "species_110096", "species_10775599" ], "modifiers": [ [ "species_10775597", "catalyst" ] ], "additional_components": [ "P27472", "YLR258W", "P47011", "YJL137C", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P27472", "YLR258W", "P47011", "YJL137C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10775616": { "compartment": "compartment_70101", "id": "reaction_10775616", "reactome": "R-SCE-3322057", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775609" ], "products": [ "species_10775614" ], "modifiers": [ [ "species_10775557", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "YEL011W" ] }, "reaction_10785555": { "compartment": "compartment_17963", "id": "reaction_10785555", "reactome": "R-SCE-8851234", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851233", "species_2022884" ], "products": [ "species_425969", "species_8851224", "species_8851226" ], "modifiers": [ [ "species_10785549", "catalyst" ] ], "additional_components": [ "species_29494", "species_30187", "species_29438", "species_110614", "species_29420", "CHEBI:58369", "species_110094", "species_110096", "P40009", "YER005W", "species_74016" ] }, "reaction_10766160": { "compartment": "compartment_5460", "id": "reaction_10766160", "reactome": "R-SCE-169270", "name": "ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766149", "species_73663" ], "products": [ "species_76633", "species_10766147" ], "modifiers": [ [ "species_10766157", "catalyst" ] ], "additional_components": [ "species_76577", "species_31649", "Q12480", "YPR004C", "P42940", "YGR207C", "species_76577", "Q12480", "YPR004C", "P42940", "YGR207C", "species_113596", "YOR356W" ] }, "reaction_10769932": { "compartment": "compartment_70101", "id": "reaction_10769932", "reactome": "R-SCE-428696", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10769929", "catalyst" ] ], "additional_components": [ "Q05521", "YDR284C", "Q04396", "YDR503C" ] }, "reaction_10781083": { "compartment": "compartment_12045", "id": "reaction_10781083", "reactome": "R-SCE-5692261", "name": "ALDH3A2-1 oxidises HD2NAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_29356", "species_428671" ], "products": [ "species_70106", "species_73473", "species_3632881" ], "modifiers": [ [ "species_10781080", "catalyst" ] ], "additional_components": [ "Q04458", "YMR110C" ] }, "reaction_10770608": { "compartment": "compartment_5460", "id": "reaction_10770608", "reactome": "R-SCE-449911", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113539", "species_113593" ], "products": [ "species_159448", "species_159450", "species_113559" ], "modifiers": [ [ "species_10770605", "catalyst" ] ], "additional_components": [ "YAL054C" ] }, "reaction_10775516": { "compartment": "compartment_70101", "id": "reaction_10775516", "reactome": "R-SCE-3322001", "name": "GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775511" ], "products": [ "species_110096", "species_10775513" ], "modifiers": [ [ "species_10775511", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10773288": { "compartment": "compartment_70616", "id": "reaction_10773288", "reactome": "R-SCE-1483165", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110577", "species_1524101" ], "products": [ "species_1524064", "species_159450" ], "modifiers": [ [ "species_10773285", "catalyst" ] ], "additional_components": [ "YBR029C" ] }, "reaction_10763560": { "compartment": "compartment_70101", "id": "reaction_10763560", "reactome": "R-SCE-74242", "name": "PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500172", "species_29372" ], "products": [ "species_113599", "species_500244" ], "modifiers": [ [ "species_10763557", "catalyst" ] ], "additional_components": [ "CHEBI:28997", "CHEBI:17596", "species_112016", "CHEBI:58576", "Q05788", "YLR209C" ] }, "reaction_10789066": { "compartment": "compartment_70101", "id": "reaction_10789066", "reactome": "R-SCE-9678749", "name": "IMPDH tetramers binds IMPDH inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763342", "species_9678719" ], "products": [ "species_10763345" ], "modifiers": [], "additional_components": [ "P38697", "YHR216W", "P50095", "YLR432W", "P50094", "YML056C", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842", "P38697", "YHR216W", "P50095", "YLR432W", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842", "P50094", "YML056C" ] }, "reaction_10773306": { "compartment": "compartment_12045", "id": "reaction_10773306", "reactome": "R-SCE-1483182", "name": "PC is hydrolyzed to PA and choline by PLD1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_264618", "species_426755" ], "modifiers": [ [ "species_10773301", "catalyst" ] ], "additional_components": [ "YKR031C" ] }, "reaction_10763387": { "compartment": "compartment_70101", "id": "reaction_10763387", "reactome": "R-SCE-73812", "name": "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111354", "species_29472", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29370", "species_111369", "species_29404", "species_29372" ], "modifiers": [ [ "species_10763384", "catalyst" ] ], "additional_components": [ "YGR061C" ] }, "reaction_10763132": { "compartment": "compartment_70101", "id": "reaction_10763132", "reactome": "R-SCE-73599", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500759", "species_113592" ], "products": [ "species_29370", "species_500761" ], "modifiers": [ [ "species_10763129", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:16704", "species_109395", "species_109402", "Q12084", "YDR020C" ] }, "reaction_10775579": { "compartment": "compartment_70101", "id": "reaction_10775579", "reactome": "R-SCE-3322009", "name": "GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775574" ], "products": [ "species_110096", "species_10775576" ], "modifiers": [ [ "species_10775574", "catalyst" ] ], "additional_components": [ "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C" ] }, "reaction_10789268": { "compartment": "compartment_70101", "id": "reaction_10789268", "reactome": "R-SCE-9717830", "name": "GGPS1 hexamer transfers IPPP to GPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191409" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10789265", "catalyst" ] ], "additional_components": [ "Q12051", "YPL069C", "species_109496" ] }, "reaction_10779036": { "compartment": "compartment_12045", "id": "reaction_10779036", "reactome": "R-SCE-5676637", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676631" ], "products": [ "species_5676634", "species_29356" ], "modifiers": [ [ "species_10779031", "catalyst" ] ], "additional_components": [ "YJL097W" ] }, "reaction_10788222": { "compartment": "compartment_70101", "id": "reaction_10788222", "reactome": "R-SCE-9014766", "name": "PXLP-K56-SRR dimer isomerises L-Ser to D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_376186" ], "modifiers": [ [ "species_10788216", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "P36007", "YKL218C" ] }, "reaction_10764143": { "compartment": "compartment_70101", "id": "reaction_10764143", "reactome": "R-SCE-75889", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_75970" ], "products": [ "species_29360", "species_76114" ], "modifiers": [ [ "species_10764140", "catalyst" ] ], "additional_components": [ "P41911", "YOL059W", "Q00055", "YDL022W" ] }, "reaction_10763361": { "compartment": "compartment_70101", "id": "reaction_10763361", "reactome": "R-SCE-73798", "name": "AICAR + 10-Formyl-THF => FAICAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111409", "species_419151" ], "products": [ "species_111427", "species_111355" ], "modifiers": [ [ "species_10763355", "catalyst" ] ], "additional_components": [ "P38009", "YMR120C" ] }, "reaction_10763112": { "compartment": "compartment_70101", "id": "reaction_10763112", "reactome": "R-SCE-73580", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_73578" ], "products": [ "species_73566", "species_76577" ], "modifiers": [ [ "species_10763109", "catalyst" ] ], "additional_components": [ "P38063", "YBL068W", "P32895", "YKL181W", "P38689", "YHL011C", "Q12265", "YOL061W", "P38620", "YER099C" ] }, "reaction_10762072": { "compartment": "compartment_70101", "id": "reaction_10762072", "reactome": "R-SCE-71670", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29370", "species_29492" ], "products": [ "species_113592", "species_29398" ], "modifiers": [ [ "species_10762069", "catalyst" ], [ "species_30014", "catalyst" ], [ "species_76183", "inhibitor" ], [ "species_30389", "inhibitor" ], [ "species_29358", "inhibitor" ] ], "additional_components": [ "P00549", "YAL038W", "species_74126", "species_109496", "P52489", "YOR347C" ] }, "reaction_10775607": { "compartment": "compartment_70101", "id": "reaction_10775607", "reactome": "R-SCE-3322025", "name": "Autoglucosylation of GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775604", "species_29410" ], "products": [ "species_110096", "species_10775511" ], "modifiers": [ [ "species_10775604", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P27472", "YLR258W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P27472", "YLR258W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10785160": { "compartment": "compartment_70101", "id": "reaction_10785160", "reactome": "R-SCE-6813749", "name": "ALDH1A1 oxidises GA to DGA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30393", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_6799497" ], "modifiers": [ [ "species_10762101", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10773606": { "compartment": "compartment_20699", "id": "reaction_10773606", "reactome": "R-SCE-1676185", "name": "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10773603", "catalyst" ] ], "additional_components": [ "P37297", "YLR305C", "P42951", "YJL100W" ] }, "reaction_10776478": { "compartment": "compartment_70101", "id": "reaction_10776478", "reactome": "R-SCE-4167511", "name": "HLCS biotinylates ACACB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_113592", "species_10776476" ], "products": [ "species_10767433", "species_111294", "species_76577" ], "modifiers": [ [ "species_10774830", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527", "Q00955", "YNR016C", "species_113527", "YDL141W" ] }, "reaction_10767652": { "compartment": "compartment_20699", "id": "reaction_10767652", "reactome": "R-SCE-202132", "name": "depalmitoylated eNOS translocates from plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767646" ], "products": [ "species_10767650" ], "modifiers": [], "additional_components": [ "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_29870", "species_113596", "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_29870", "species_113596" ] }, "reaction_10767486": { "compartment": "compartment_70101", "id": "reaction_10767486", "reactome": "R-SCE-200644", "name": "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_200739" ], "products": [ "species_70106", "species_29364", "species_200640" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10773135": { "compartment": "compartment_12045", "id": "reaction_10773135", "reactome": "R-SCE-1482828", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2[4]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10773132", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10769054": { "compartment": "compartment_17951", "id": "reaction_10769054", "reactome": "R-SCE-390251", "name": "HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390248", "species_192307" ], "products": [ "species_193465", "species_390241", "species_192305" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10767494": { "compartment": "compartment_876", "id": "reaction_10767494", "reactome": "R-SCE-200646", "name": "Cytosolic folate export across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965" ], "products": [ "species_200716" ], "modifiers": [ [ "species_10767491", "catalyst" ] ], "additional_components": [ "YJL163C" ] }, "reaction_10768943": { "compartment": "compartment_17951", "id": "reaction_10768943", "reactome": "R-SCE-389639", "name": "phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389537", "species_389615", "species_113535" ], "products": [ "species_389594", "species_389583", "species_389536" ], "modifiers": [ [ "species_10768940", "catalyst" ] ], "additional_components": [ "P47181", "YJR154W", "species_111793" ] }, "reaction_10788342": { "compartment": "compartment_70101", "id": "reaction_10788342", "reactome": "R-SCE-9018877", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023708", "species_29356" ], "products": [ "species_9023712" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10763152": { "compartment": "compartment_70101", "id": "reaction_10763152", "reactome": "R-SCE-73608", "name": "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500829", "species_29356" ], "products": [ "species_31633", "species_500430" ], "modifiers": [ [ "species_10763149", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:15698", "CHEBI:16704", "CHEBI:16450", "species_158417", "Q06549", "YLR245C" ] }, "reaction_10772970": { "compartment": "compartment_12045", "id": "reaction_10772970", "reactome": "R-SCE-1482571", "name": "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498738", "species_29356" ], "products": [ "species_1524023", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10786551": { "compartment": "compartment_70101", "id": "reaction_10786551", "reactome": "R-SCE-8869606", "name": "NMRK1 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10786548", "catalyst" ] ], "additional_components": [ "YNL129W" ] }, "reaction_10773475": { "compartment": "compartment_876", "id": "reaction_10773475", "reactome": "R-SCE-1675810", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_1806240" ], "modifiers": [ [ "species_10773418", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10781631": { "compartment": "compartment_5460", "id": "reaction_10781631", "reactome": "R-SCE-5696091", "name": "ALDH1B1 tetramer oxidises CH3CHO to CH3COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_113532" ], "products": [ "species_113539", "species_29362", "species_113529" ], "modifiers": [ [ "species_10781628", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10770185": { "compartment": "compartment_17906", "id": "reaction_10770185", "reactome": "R-SCE-434382", "name": "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_3632881", "species_113592" ], "products": [ "species_111294", "species_76577", "species_200993" ], "modifiers": [ [ "species_10770182", "catalyst" ] ], "additional_components": [ "P47912", "YMR246W", "P39002", "YIL009W", "P30624", "YOR317W" ] }, "reaction_10767476": { "compartment": "compartment_70101", "id": "reaction_10767476", "reactome": "R-SCE-200555", "name": "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10764049", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "P32874", "YMR207C" ] }, "reaction_10782610": { "compartment": "compartment_5460", "id": "reaction_10782610", "reactome": "R-SCE-6792572", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781283", "species_10782600" ], "products": [ "species_10782602", "species_10781285" ], "modifiers": [ [ "species_10782607", "catalyst" ] ], "additional_components": [ "YAL044C", "P32473", "YBR221C", "species_29480", "P20967", "YIL125W", "CHEBI:17460", "P16387", "YER178W", "P09624", "YFL018C", "species_113596", "P19262", "YDR148C", "P12695", "YNL071W", "P32473", "YBR221C", "species_29480", "P20967", "YIL125W", "P16387", "YER178W", "CHEBI:17460", "P09624", "YFL018C", "species_113596", "P12695", "YNL071W", "P19262", "YDR148C", "YAL044C", "YJL046W" ] }, "reaction_10762216": { "compartment": "compartment_70101", "id": "reaction_10762216", "reactome": "R-SCE-71802", "name": "D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_29370", "species_30533" ], "modifiers": [ [ "species_10762213", "catalyst" ], [ "species_30533", "catalyst" ] ], "additional_components": [ "Q12471", "YOL136C", "Q06137", "YLR345W", "P32604", "YJL155C" ] }, "reaction_10773173": { "compartment": "compartment_12045", "id": "reaction_10773173", "reactome": "R-SCE-1482920", "name": "PG is hydrolyzed to 2-acyl LPG by PLA2[14]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498730", "species_1524021" ], "modifiers": [ [ "species_10773170", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10785552": { "compartment": "compartment_17963", "id": "reaction_10785552", "reactome": "R-SCE-8851225", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851224", "species_2022884" ], "products": [ "species_8851227", "species_425969", "species_8851226" ], "modifiers": [ [ "species_10785549", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58369", "species_110094", "species_110096", "species_109366", "species_109395", "species_109402", "species_113578", "P40009", "YER005W", "species_74016" ] }, "reaction_10765673": { "compartment": "compartment_7660", "id": "reaction_10765673", "reactome": "R-SCE-163743", "name": "Transcriptional activation of Acetyl-CoA carboxylase by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10765671" ], "modifiers": [], "additional_components": [ "Q00955", "YNR016C", "P32874", "YMR207C" ] }, "reaction_10784150": { "compartment": "compartment_5460", "id": "reaction_10784150", "reactome": "R-SCE-6801462", "name": "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6801458", "species_113521" ], "products": [ "species_5389850" ], "modifiers": [ [ "species_10784132", "catalyst" ] ], "additional_components": [ "YBR084W" ] }, "reaction_10769083": { "compartment": "compartment_17947", "id": "reaction_10769083", "reactome": "R-SCE-390393", "name": "Peroxisomal uptake of very long-chain fatty acyl CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390394" ], "products": [ "species_390260" ], "modifiers": [ [ "species_10768823", "catalyst" ] ], "additional_components": [ "P41909", "YPL147W" ] }, "reaction_10766760": { "compartment": "compartment_70101", "id": "reaction_10766760", "reactome": "R-SCE-191405", "name": "Two FPP molecules dimerize to form presqualene diphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191385" ], "products": [ "species_191265", "species_111294" ], "modifiers": [ [ "species_10766755", "catalyst" ] ], "additional_components": [ "P29704", "YHR190W", "species_109496" ] }, "reaction_10781904": { "compartment": "compartment_5460", "id": "reaction_10781904", "reactome": "R-SCE-6784224", "name": "PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784215" ], "products": [ "species_6784241" ], "modifiers": [ [ "species_10781901", "catalyst" ] ], "additional_components": [ "P09368", "YLR142W", "species_113596" ] }, "reaction_10763162": { "compartment": "compartment_70101", "id": "reaction_10763162", "reactome": "R-SCE-73647", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29494", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_110614", "species_29372" ], "modifiers": [ [ "species_10763159", "catalyst" ] ], "additional_components": [ "P28274", "YBL039C" ] }, "reaction_10786543": { "compartment": "compartment_70101", "id": "reaction_10786543", "reactome": "R-SCE-8869241", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_426639" ], "products": [ "species_426658", "species_426755" ], "modifiers": [ [ "species_10786540", "catalyst" ] ], "additional_components": [ "YOR022C" ] }, "reaction_10767496": { "compartment": "compartment_70101", "id": "reaction_10767496", "reactome": "R-SCE-200651", "name": "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_200739" ], "products": [ "species_200736", "species_197969" ], "modifiers": [ [ "species_10761810", "catalyst" ] ], "additional_components": [ "P37292", "YBR263W" ] }, "reaction_10777429": { "compartment": "compartment_17957", "id": "reaction_10777429", "reactome": "R-SCE-5250531", "name": "ARV1 transports CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193384" ], "products": [ "species_171095" ], "modifiers": [ [ "species_10777426", "catalyst" ] ], "additional_components": [ "YLR242C" ] }, "reaction_10767533": { "compartment": "compartment_876", "id": "reaction_10767533", "reactome": "R-SCE-200729", "name": "SLC46A1 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200716" ], "products": [ "species_197965" ], "modifiers": [ [ "species_10767491", "catalyst" ] ], "additional_components": [ "YJL163C" ] }, "reaction_10781613": { "compartment": "compartment_17906", "id": "reaction_10781613", "reactome": "R-SCE-5696074", "name": "AGK:Mg2+ phosphorylates MAG, DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696069", "species_5696066" ], "products": [ "species_5696026", "species_5696037" ], "modifiers": [ [ "species_10781610", "catalyst" ] ], "additional_components": [ "species_6797635", "species_6814795", "species_1602448", "species_417891", "Q12246", "YOR171C", "P47045", "TIM54", "species_109496", "Q06147", "YLR260W" ] }, "reaction_10788346": { "compartment": "compartment_70101", "id": "reaction_10788346", "reactome": "R-SCE-9020253", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024781", "species_29356" ], "products": [ "species_9024809" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "CHEBI:138649", "CHEBI:138648", "species_158417", "Q10740", "YNL045W" ] }, "reaction_10781648": { "compartment": "compartment_5460", "id": "reaction_10781648", "reactome": "R-SCE-5696839", "name": "MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_6801451", "species_113593" ], "products": [ "species_5389850", "species_113548", "species_113581" ], "modifiers": [ [ "species_10781645", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10784754": { "compartment": "compartment_70101", "id": "reaction_10784754", "reactome": "R-SCE-6809680", "name": "MTMR12 binds MTM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773463", "species_10784750" ], "products": [ "species_10784752" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10781641": { "compartment": "compartment_12045", "id": "reaction_10781641", "reactome": "R-SCE-5696448", "name": "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696449", "species_6782195" ], "products": [ "species_76194", "species_1500596" ], "modifiers": [ [ "species_10781638", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10789150": { "compartment": "compartment_70101", "id": "reaction_10789150", "reactome": "R-SCE-9695949", "name": "SPHK2 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_29370", "species_428203" ], "modifiers": [ [ "species_10769846", "catalyst" ], [ "species_10789148", "inhibitor" ] ], "additional_components": [ "Q12246", "YOR171C", "P47045", "TIM54", "Q06147", "YLR260W", "LigandDisplayForward?ligandId=6625", "Q12246", "YOR171C", "LigandDisplayForward?ligandId=10641", "P47045", "TIM54", "LigandDisplayForward?ligandId=10219", "LigandDisplayForward?ligandId=6624", "Q06147", "YLR260W" ] }, "reaction_10781989": { "compartment": "compartment_17951", "id": "reaction_10781989", "reactome": "R-SCE-6786720", "name": "DECR2 reduces LCtE-CoA to t3enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_113602", "species_6786723" ], "products": [ "species_389556", "species_6786715" ], "modifiers": [ [ "species_10781986", "catalyst" ] ], "additional_components": [ "YNL202W" ] }, "reaction_10773159": { "compartment": "compartment_12045", "id": "reaction_10773159", "reactome": "R-SCE-1482889", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_76194", "species_1500594" ], "modifiers": [ [ "species_10771182", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10767517": { "compartment": "compartment_70616", "id": "reaction_10767517", "reactome": "R-SCE-200680", "name": "SLC25A32 transports THF from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111355" ], "products": [ "species_200671" ], "modifiers": [ [ "species_10767514", "catalyst" ] ], "additional_components": [ "YIL134W" ] }, "reaction_10768215": { "compartment": "compartment_70101", "id": "reaction_10768215", "reactome": "R-SCE-265295", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10768212", "catalyst" ] ], "additional_components": [ "YKL117W" ] }, "reaction_10774833": { "compartment": "compartment_70101", "id": "reaction_10774833", "reactome": "R-SCE-2993802", "name": "HLCS biotinylates PC:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_10774820", "species_113592" ], "products": [ "species_10774825", "species_111294", "species_76577" ], "modifiers": [ [ "species_10774830", "catalyst" ] ], "additional_components": [ "P11154", "YGL062W", "species_113527", "P11154", "YGL062W", "species_113527", "YDL141W" ] }, "reaction_10781981": { "compartment": "compartment_70101", "id": "reaction_10781981", "reactome": "R-SCE-6786650", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_29356" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10781978", "catalyst" ] ], "additional_components": [ "Q12204", "YOR022C" ] }, "reaction_10773485": { "compartment": "compartment_12045", "id": "reaction_10773485", "reactome": "R-SCE-1675813", "name": "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_29370", "species_1806234" ], "modifiers": [ [ "species_10773482", "catalyst" ] ], "additional_components": [ "P37297", "YLR305C", "P42951", "YJL100W" ] }, "reaction_10786556": { "compartment": "compartment_70101", "id": "reaction_10786556", "reactome": "R-SCE-8869607", "name": "NMRK2 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10786553", "catalyst" ] ], "additional_components": [ "YNL129W" ] }, "reaction_10761919": { "compartment": "compartment_5460", "id": "reaction_10761919", "reactome": "R-SCE-71397", "name": "lipo-PDH decarboxylates PYR to Ac-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113557", "species_113526" ], "products": [ "species_29376", "species_29362", "species_113559" ], "modifiers": [ [ "species_10761916", "catalyst" ] ], "additional_components": [ "P32473", "YBR221C", "species_29480", "P16387", "YER178W", "P09624", "YFL018C", "species_113596", "P12695", "YNL071W" ] }, "reaction_10762130": { "compartment": "compartment_70101", "id": "reaction_10762130", "reactome": "R-SCE-71707", "name": "ethanol + NAD+ => acetaldehyde + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30203", "species_29360" ], "products": [ "species_70106", "species_73473", "species_29510" ], "modifiers": [ [ "species_10762127", "catalyst" ] ], "additional_components": [ "species_158417", "P32771", "YDL168W" ] }, "reaction_10773425": { "compartment": "compartment_876", "id": "reaction_10773425", "reactome": "R-SCE-1675773", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_202247" ], "products": [ "species_29370", "species_179838" ], "modifiers": [ [ "species_10773418", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10773535": { "compartment": "compartment_171062", "id": "reaction_10773535", "reactome": "R-SCE-1675939", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806200" ], "modifiers": [ [ "species_10773532", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "species_113527" ] }, "reaction_10773153": { "compartment": "compartment_12045", "id": "reaction_10773153", "reactome": "R-SCE-1482867", "name": "DLCL is acylated to MLCL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524080", "species_1500578" ], "products": [ "species_76194", "species_1524069" ], "modifiers": [ [ "species_10764105", "catalyst" ] ], "additional_components": [ "YBR042C" ] }, "reaction_10767135": { "compartment": "compartment_70101", "id": "reaction_10767135", "reactome": "R-SCE-198563", "name": "IDO1 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29500" ], "products": [ "species_33179" ], "modifiers": [ [ "species_10767132", "catalyst" ] ], "additional_components": [ "P47125", "YJR078W", "species_189444" ] }, "reaction_10769042": { "compartment": "compartment_17951", "id": "reaction_10769042", "reactome": "R-SCE-389986", "name": "trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389894", "species_141343" ], "products": [ "species_389982" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10773514": { "compartment": "compartment_876", "id": "reaction_10773514", "reactome": "R-SCE-1675836", "name": "PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806276", "species_29372" ], "modifiers": [ [ "species_10773511", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "Q08227", "YOL065C", "P50942", "YNL106C" ] }, "reaction_10766591": { "compartment": "compartment_5460", "id": "reaction_10766591", "reactome": "R-SCE-189465", "name": "FECH binds Fe2+ to PRIN9 to form heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189487", "species_113531" ], "products": [ "species_189444", "species_113529" ], "modifiers": [ [ "species_10766588", "catalyst" ], [ "species_391232", "inhibitor" ] ], "additional_components": [ "P16622", "YOR176W" ] }, "reaction_10766702": { "compartment": "compartment_70101", "id": "reaction_10766702", "reactome": "R-SCE-191303", "name": "FDPS dimer transfers IPPP to GPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191409" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10766699", "catalyst" ] ], "additional_components": [ "P08524", "YJL167W", "species_109496" ] }, "reaction_10786562": { "compartment": "compartment_70101", "id": "reaction_10786562", "reactome": "R-SCE-8869633", "name": "NMRK1 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_70106", "species_29370", "species_8869353" ], "modifiers": [ [ "species_10786548", "catalyst" ] ], "additional_components": [ "YNL129W" ] }, "reaction_10766720": { "compartment": "compartment_70101", "id": "reaction_10766720", "reactome": "R-SCE-191352", "name": "HMGCR dimer reduces bHMG-CoA to MVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191374" ], "products": [ "species_76194", "species_29366", "species_191424" ], "modifiers": [ [ "species_10766717", "catalyst" ] ], "additional_components": [ "P12683", "YML075C" ] }, "reaction_10767740": { "compartment": "compartment_20699", "id": "reaction_10767740", "reactome": "R-SCE-203700", "name": "eNOS translocation from Golgi to Caveolae", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767716" ], "products": [ "species_10767589" ], "modifiers": [], "additional_components": [ "YHR042W", "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_113596" ] }, "reaction_10772965": { "compartment": "compartment_70616", "id": "reaction_10772965", "reactome": "R-SCE-1482546", "name": "2-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524047", "species_1524038" ], "products": [ "species_1524042", "species_29374" ], "modifiers": [ [ "species_10772962", "catalyst" ] ], "additional_components": [ "YDL142C" ] }, "reaction_10769833": { "compartment": "compartment_70101", "id": "reaction_10769833", "reactome": "R-SCE-428185", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428163", "species_428139" ], "products": [ "species_76194", "species_428126" ], "modifiers": [ [ "species_10769830", "catalyst" ] ], "additional_components": [ "P38703", "YHL003C", "P28496", "YKL008C" ] }, "reaction_10787624": { "compartment": "compartment_5460", "id": "reaction_10787624", "reactome": "R-SCE-8952873", "name": "MECR dimer reduces tdec2-CoA to DEC-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_77343", "species_113529" ], "products": [ "species_113563", "species_77308" ], "modifiers": [ [ "species_10787621", "catalyst" ] ], "additional_components": [ "P38071", "YBR026C" ] }, "reaction_10786524": { "compartment": "compartment_12045", "id": "reaction_10786524", "reactome": "R-SCE-8867876", "name": "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_392417" ], "products": [ "species_1806234", "species_33625" ], "modifiers": [ [ "species_10786521", "catalyst" ] ], "additional_components": [ "P38755", "YHR001W", "P35844", "YPL145C", "P35843", "YOR237W" ] }, "reaction_10769008": { "compartment": "compartment_17951", "id": "reaction_10769008", "reactome": "R-SCE-389826", "name": "glyoxylate + NADPH + H+ => glycolate + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_113602", "species_389678" ], "products": [ "species_389822", "species_389556" ], "modifiers": [ [ "species_10769005", "catalyst" ] ], "additional_components": [ "YPL113C" ] }, "reaction_10785535": { "compartment": "compartment_984", "id": "reaction_10785535", "reactome": "R-SCE-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8936166" ], "products": [ "species_109277", "species_351626", "species_8851092" ], "modifiers": [ [ "species_10785532", "catalyst" ] ], "additional_components": [ "species_29494", "species_113592", "species_2509836", "species_29438", "species_110614", "species_29420", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10786911": { "compartment": "compartment_70101", "id": "reaction_10786911", "reactome": "R-SCE-8876889", "name": "Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10767435", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527" ] }, "reaction_10769786": { "compartment": "compartment_70101", "id": "reaction_10769786", "reactome": "R-SCE-428123", "name": "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_428182" ], "products": [ "species_29366", "species_428163" ], "modifiers": [ [ "species_10769783", "catalyst" ] ], "additional_components": [ "YBR265W" ] }, "reaction_10785504": { "compartment": "compartment_984", "id": "reaction_10785504", "reactome": "R-SCE-8850846", "name": "NTPDase1 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785501", "catalyst" ] ], "additional_components": [ "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10761841": { "compartment": "compartment_70101", "id": "reaction_10761841", "reactome": "R-SCE-71296", "name": "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31467", "species_29356" ], "products": [ "species_29996" ], "modifiers": [ [ "species_10761838", "catalyst" ] ], "additional_components": [ "YHR163W" ] }, "reaction_10776243": { "compartment": "compartment_70101", "id": "reaction_10776243", "reactome": "R-SCE-3780997", "name": "PPP1R3C binds to glycogen:GYG2:GYS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775586", "species_10776211" ], "products": [ "species_10776213" ], "modifiers": [], "additional_components": [ "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "Q06216", "YLR273C", "P28006", "YOR178C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10778265": { "compartment": "compartment_7660", "id": "reaction_10778265", "reactome": "R-SCE-5649799", "name": "DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10778250" ], "products": [ "species_10778263", "species_77502" ], "modifiers": [ [ "species_10778255", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YDR440W" ] }, "reaction_10775068": { "compartment": "compartment_7660", "id": "reaction_10775068", "reactome": "R-SCE-3215385", "name": "CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775059" ], "products": [ "species_10775065" ], "modifiers": [ [ "species_10775059", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10778269": { "compartment": "compartment_7660", "id": "reaction_10778269", "reactome": "R-SCE-5649801", "name": "DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_77502", "species_10778245" ], "modifiers": [ [ "species_10778255", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YDR440W" ] }, "reaction_10776189": { "compartment": "compartment_7660", "id": "reaction_10776189", "reactome": "R-SCE-3777129", "name": "HDAC3 containing complexes deacetylate histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10776109" ], "products": [ "species_5566518", "species_10776115" ], "modifiers": [ [ "species_10776186", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "CHEBI:57627", "P53096", "YGL194C", "P38262", "YBR103W", "P25357", "YCR033W" ] }, "reaction_10777324": { "compartment": "compartment_7660", "id": "reaction_10777324", "reactome": "R-SCE-5225649", "name": "RBBP7 binds histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_10775913" ], "products": [ "species_10777322" ], "modifiers": [ [ "species_10777305", "inhibitor" ] ], "additional_components": [ "P36012", "YKL049C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P39984", "YEL056W", "Q12363", "YOR230W", "P13712", "YBR195C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P39984", "YEL056W", "Q12363", "YOR230W", "P36012", "YKL049C", "P13712", "YBR195C", "P36012", "YKL049C" ] }, "reaction_10778200": { "compartment": "compartment_7660", "id": "reaction_10778200", "reactome": "R-SCE-5637686", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775017", "species_77087" ], "products": [ "species_77502", "species_10776782" ], "modifiers": [ [ "species_10778197", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P46995", "YJL168C", "P38827", "YHR119W", "P43132", "YLR015W", "P36124", "YKR029C", "Q12529", "YPL165C", "P39706", "YAR003W", "Q12504", "YDR257C", "P38222", "YBR030W", "P38123", "YBR175W" ] }, "reaction_10777042": { "compartment": "compartment_7660", "id": "reaction_10777042", "reactome": "R-SCE-5205798", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763701", "species_77087" ], "products": [ "species_10777039", "species_77502" ], "modifiers": [ [ "species_10775032", "catalyst" ] ], "additional_components": [ "YBR009C", "YBR009C", "YBR034C" ] }, "reaction_10777010": { "compartment": "compartment_7660", "id": "reaction_10777010", "reactome": "R-SCE-5159245", "name": "SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_10775017", "species_77502" ], "modifiers": [ [ "species_10777007", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P46995", "YJL168C", "P38827", "YHR119W", "P43132", "YLR015W", "P36124", "YKR029C", "P39706", "YAR003W", "Q12504", "YDR257C", "P38123", "YBR175W", "P38222", "YBR030W" ] }, "reaction_10777320": { "compartment": "compartment_7660", "id": "reaction_10777320", "reactome": "R-SCE-5225602", "name": "WDR5 binds Me2sR3-replicative histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777305", "species_10776991" ], "products": [ "species_10777318" ], "modifiers": [], "additional_components": [ "P36012", "YKL049C", "YBR175W", "P36012", "YKL049C", "P38123", "YBR175W" ] }, "reaction_10777047": { "compartment": "compartment_7660", "id": "reaction_10777047", "reactome": "R-SCE-5205799", "name": "CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_77502", "species_10775241" ], "modifiers": [ [ "species_10775065", "catalyst" ], [ "species_10777045", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "Q06488", "YLR357W", "P43609", "YFR037C", "P38274", "YBR133C", "P22082", "YOR290C", "P80428", "YJL081C", "P32597", "YIL126W", "P25632", "YCR052W", "Q12406", "YPR034W", "P53628", "YNR023W", "Q05123", "YMR033W", "Q06168", "YLR321C", "P32591", "YJL176C" ] }, "reaction_10778587": { "compartment": "compartment_7660", "id": "reaction_10778587", "reactome": "R-SCE-5661117", "name": "CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10775241" ], "products": [ "species_10778585", "species_77502" ], "modifiers": [ [ "species_10775065", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10776165": { "compartment": "compartment_7660", "id": "reaction_10776165", "reactome": "R-SCE-3769447", "name": "HDAC1:2-containing complex deacetylate histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10776109" ], "products": [ "species_5566518", "species_10776115" ], "modifiers": [ [ "species_10776160", "catalyst" ], [ "species_10776163", "inhibitor" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P09547", "YPL016W", "Q12206", "YOR229W", "Q03010", "YPL139C", "Q03124", "YML127W", "P40505", "YIL084C", "P39984", "YEL056W", "Q12363", "YOR230W", "P13712", "YBR195C", "P31385", "YAL013W", "P38429", "YMR263W", "Q12214", "YPR068C", "LigandDisplayForward?ligandId=7489", "P09547", "YPL016W", "Q03124", "YML127W", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "P39984", "YEL056W", "LigandDisplayForward?ligandId=6852", "P31385", "YAL013W", "LigandDisplayForward?ligandId=7496", "Q12214", "YPR068C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P40505", "YIL084C", "Q12363", "YOR230W", "P13712", "YBR195C", "P38429", "YMR263W" ] }, "reaction_10777211": { "compartment": "compartment_7660", "id": "reaction_10777211", "reactome": "R-SCE-5205867", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777175", "species_77087" ], "products": [ "species_77502", "species_10777209" ], "modifiers": [ [ "species_10775032", "catalyst" ] ], "additional_components": [ "P04912", "YBL003C", "P04911", "YDR225W", "P04912", "YBL003C", "P04911", "YDR225W", "YBR034C" ] }, "reaction_10778258": { "compartment": "compartment_7660", "id": "reaction_10778258", "reactome": "R-SCE-5649764", "name": "DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10778245" ], "products": [ "species_77502", "species_10778250" ], "modifiers": [ [ "species_10778255", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YDR440W" ] }, "reaction_10778598": { "compartment": "compartment_7660", "id": "reaction_10778598", "reactome": "R-SCE-5661126", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777039", "species_77087" ], "products": [ "species_10778596", "species_77502" ], "modifiers": [ [ "species_10775032", "catalyst" ] ], "additional_components": [ "YBR009C", "YBR009C", "YBR034C" ] }, "reaction_10778237": { "compartment": "compartment_7660", "id": "reaction_10778237", "reactome": "R-SCE-5638157", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776742", "species_77087" ], "products": [ "species_10778230", "species_77502" ], "modifiers": [ [ "species_10776872", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P46995", "YJL168C", "Q12529", "YPL165C", "P38890", "YHR207C" ] }, "reaction_10776851": { "compartment": "compartment_7660", "id": "reaction_10776851", "reactome": "R-SCE-4827382", "name": "SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10776759" ], "products": [ "species_10776843", "species_77502" ], "modifiers": [ [ "species_10776848", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YHR119W" ] }, "reaction_10778273": { "compartment": "compartment_7660", "id": "reaction_10778273", "reactome": "R-SCE-5649802", "name": "WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10776818" ], "products": [ "species_10778271", "species_77502" ], "modifiers": [ [ "species_10776856", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YJL168C" ] }, "reaction_10776875": { "compartment": "compartment_7660", "id": "reaction_10776875", "reactome": "R-SCE-4827383", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_10776742", "species_77502" ], "modifiers": [ [ "species_10776872", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P46995", "YJL168C", "Q12529", "YPL165C", "P38890", "YHR207C" ] }, "reaction_10777413": { "compartment": "compartment_7660", "id": "reaction_10777413", "reactome": "R-SCE-5244692", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10776782" ], "products": [ "species_10777406", "species_77502" ], "modifiers": [ [ "species_10777410", "catalyst" ], [ "species_10777134", "inhibitor" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P38827", "YHR119W", "P43132", "YLR015W", "P36124", "YKR029C", "Q12529", "YPL165C", "P39706", "YAR003W", "P38123", "YBR175W", "P36012", "YKL049C" ] }, "reaction_10789077": { "compartment": "compartment_7660", "id": "reaction_10789077", "reactome": "R-SCE-9679787", "name": "HDAC1:2-containing complex binds HDAC2 Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776160", "species_9679795" ], "products": [ "species_10776163" ], "modifiers": [], "additional_components": [ "P09547", "YPL016W", "Q12206", "YOR229W", "Q03010", "YPL139C", "Q03124", "YML127W", "P40505", "YIL084C", "P39984", "YEL056W", "Q12363", "YOR230W", "P13712", "YBR195C", "P31385", "YAL013W", "P38429", "YMR263W", "Q12214", "YPR068C", "LigandDisplayForward?ligandId=7489", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "LigandDisplayForward?ligandId=6852", "LigandDisplayForward?ligandId=7496", "LigandDisplayForward?ligandId=7489", "P09547", "YPL016W", "Q03124", "YML127W", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "P39984", "YEL056W", "LigandDisplayForward?ligandId=6852", "P31385", "YAL013W", "LigandDisplayForward?ligandId=7496", "Q12214", "YPR068C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P40505", "YIL084C", "Q12363", "YOR230W", "P13712", "YBR195C", "P38429", "YMR263W" ] }, "reaction_10778240": { "compartment": "compartment_7660", "id": "reaction_10778240", "reactome": "R-SCE-5638333", "name": "WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_10776823", "species_77502" ], "modifiers": [ [ "species_10776856", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YJL168C" ] }, "reaction_10778267": { "compartment": "compartment_7660", "id": "reaction_10778267", "reactome": "R-SCE-5649800", "name": "WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10776823" ], "products": [ "species_77502", "species_10776818" ], "modifiers": [ [ "species_10776856", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YJL168C" ] }, "reaction_10776286": { "compartment": "compartment_7660", "id": "reaction_10776286", "reactome": "R-SCE-3782655", "name": "HDAC10 deacetylates histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10776109" ], "products": [ "species_5566518", "species_10776115" ], "modifiers": [ [ "species_10776283", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "YNL021W" ] }, "reaction_10778195": { "compartment": "compartment_70101", "id": "reaction_10778195", "reactome": "R-SCE-5634802", "name": "MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778184", "species_71284" ], "products": [ "species_71285", "species_10778188" ], "modifiers": [ [ "species_10778190", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YDR216W" ] }, "reaction_10782722": { "compartment": "compartment_876", "id": "reaction_10782722", "reactome": "R-SCE-6797630", "name": "LRPP4(LRPP1-3,5) hydrolyse LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_417891", "species_109276" ], "products": [ "species_6797635", "species_109277" ], "modifiers": [ [ "species_10782719", "catalyst" ] ], "additional_components": [ "Q05521", "YDR284C", "Q04396", "YDR503C" ] }, "reaction_10769347": { "compartment": "compartment_876", "id": "reaction_10769347", "reactome": "R-SCE-418574", "name": "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769184" ], "products": [ "species_10769344" ], "modifiers": [ [ "species_10769184", "catalyst" ] ], "additional_components": [ "species_29438", "P10823", "YER020W", "species_111349", "P10823", "YER020W", "species_29438", "P10823", "YER020W" ] }, "reaction_10769393": { "compartment": "compartment_70101", "id": "reaction_10769393", "reactome": "R-SCE-419166", "name": "GEFs activate RhoA,B,C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10769303" ], "products": [ "species_10769305", "species_29420" ], "modifiers": [ [ "species_10769390", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_111349", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q05670", "YMR232W", "P04821", "YLR310C", "P34216", "YBL047C", "P07866", "YAL024C", "P25300", "YCR038C" ] }, "reaction_10769338": { "compartment": "compartment_70101", "id": "reaction_10769338", "reactome": "R-SCE-418553", "name": "cAMP degradation by Phosphodiesterases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_29356" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10769330", "catalyst" ] ], "additional_components": [ "YOR360C" ] }, "reaction_10770069": { "compartment": "compartment_70101", "id": "reaction_10770069", "reactome": "R-SCE-429860", "name": "DCP1-DCP2 complex decaps mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770038", "species_29356" ], "products": [ "species_430004", "species_10770040" ], "modifiers": [ [ "species_10770066", "catalyst" ] ], "additional_components": [ "P25644", "YCR077C", "P40070", "YER112W", "P57743", "YLR438C-A", "P53905", "YNL147W", "P40089", "YER146W", "P47017", "YJL124C", "Q06406", "YDR378C", "P38203", "YBL026W", "P25644", "YCR077C", "P40070", "YER112W", "P57743", "YLR438C-A", "P53905", "YNL147W", "P40089", "YER146W", "P47017", "YJL124C", "Q06406", "YDR378C", "P38203", "YBL026W", "P39517", "YDL160C", "P53550", "YNL118C", "P39998", "YEL015W", "Q12517", "YOL149W" ] }, "reaction_10770142": { "compartment": "compartment_70101", "id": "reaction_10770142", "reactome": "R-SCE-430028", "name": "Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429974", "species_29356" ], "products": [ "species_109395", "species_109402", "species_429926", "species_76577", "species_113578" ], "modifiers": [ [ "species_10770139", "catalyst" ] ], "additional_components": [ "Q02793", "SKI8", "P53859", "CSL4", "Q08285", "RRP40", "Q12277", "RRP42", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "P35207", "SKI2", "P53256", "RRP46", "P38792", "RRP4", "P48240", "MTR3", "Q08162", "DIS3", "P17883", "SKI3" ] }, "reaction_10770077": { "compartment": "compartment_70101", "id": "reaction_10770077", "reactome": "R-SCE-429961", "name": "DCPS scavenges the 7-methylguanosine cap of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429926", "species_29356" ], "products": [ "species_429925", "species_430042" ], "modifiers": [ [ "species_10770074", "catalyst" ] ], "additional_components": [ "YLR270W" ] }, "reaction_10770079": { "compartment": "compartment_70101", "id": "reaction_10770079", "reactome": "R-SCE-429978", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429974", "species_10770036" ], "products": [ "species_10770038" ], "modifiers": [], "additional_components": [ "P25644", "YCR077C", "P40070", "YER112W", "P57743", "YLR438C-A", "P53905", "YNL147W", "P40089", "YER146W", "P47017", "YJL124C", "Q06406", "YDR378C", "P38203", "YBL026W", "P25644", "YCR077C", "P40070", "YER112W", "P57743", "YLR438C-A", "P53905", "YNL147W", "P40089", "YER146W", "P47017", "YJL124C", "Q06406", "YDR378C", "P38203", "YBL026W" ] }, "reaction_10771594": { "compartment": "compartment_876", "id": "reaction_10771594", "reactome": "R-SCE-917870", "name": "SLC46A1 transports hemes from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310" ], "products": [ "species_9707308" ], "modifiers": [ [ "species_10767491", "catalyst" ] ], "additional_components": [ "species_189444", "CHEBI:36144", "species_189444", "CHEBI:36144", "YJL163C" ] }, "reaction_10769319": { "compartment": "compartment_876", "id": "reaction_10769319", "reactome": "R-SCE-418309", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016" ], "products": [ "species_74112" ], "modifiers": [ [ "species_10769310", "catalyst" ] ], "additional_components": [ "YGL006W" ] }, "reaction_10777836": { "compartment": "compartment_70101", "id": "reaction_10777836", "reactome": "R-SCE-5578910", "name": "KCNK dimers transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10777833", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10777914": { "compartment": "compartment_876", "id": "reaction_10777914", "reactome": "R-SCE-5617178", "name": "ATP2B4 binds to NOS1, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769316", "species_10769321" ], "products": [ "species_10777912" ], "modifiers": [], "additional_components": [ "YGL006W", "YHR042W", "P16603", "YHR042W", "P38929", "YGL006W" ] }, "reaction_10789363": { "compartment": "compartment_7660", "id": "reaction_10789363", "reactome": "R-SCE-9757256", "name": "MCM3 binds MCM5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760359", "species_10760355" ], "products": [ "species_10760361" ], "modifiers": [], "additional_components": [ "P24279", "MCM3", "P29496", "MCM5" ] }, "reaction_10789309": { "compartment": "compartment_7660", "id": "reaction_10789309", "reactome": "R-SCE-9749197", "name": "ORC1 binds to H4K20me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789305", "species_10760200" ], "products": [ "species_10789307" ], "modifiers": [], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "P54784", "phospho-ORC1", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10789288": { "compartment": "compartment_70101", "id": "reaction_10789288", "reactome": "R-SCE-9734730", "name": "ORC1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789286" ], "products": [ "species_10760200" ], "modifiers": [], "additional_components": [] }, "reaction_10789367": { "compartment": "compartment_7660", "id": "reaction_10789367", "reactome": "R-SCE-9757258", "name": "MCM2 binds MCM4:MCM6:MCM7 heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760349", "species_10760335" ], "products": [ "species_10760351" ], "modifiers": [], "additional_components": [ "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6" ] }, "reaction_10760180": { "compartment": "compartment_7660", "id": "reaction_10760180", "reactome": "R-SCE-68595", "name": "ORC2 binds ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760176", "species_10760172" ], "products": [ "species_10760178" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P54790", "ORC3" ] }, "reaction_10760188": { "compartment": "compartment_7660", "id": "reaction_10760188", "reactome": "R-SCE-68603", "name": "ORC5 binds ORC2:ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760178", "species_10760184" ], "products": [ "species_10760186" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P54790", "ORC3", "P32833", "ORC2", "P50874", "ORC5", "P54790", "ORC3" ] }, "reaction_10760196": { "compartment": "compartment_7660", "id": "reaction_10760196", "reactome": "R-SCE-68610", "name": "Formation of ORC(2-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760192", "species_10760186" ], "products": [ "species_10760194" ], "modifiers": [ [ "species_29358", "catalyst" ] ], "additional_components": [ "P32833", "ORC2", "P50874", "ORC5", "P54790", "ORC3", "P32833", "ORC2", "P54791", "ORC4", "P50874", "ORC5", "P54790", "ORC3" ] }, "reaction_10760222": { "compartment": "compartment_7660", "id": "reaction_10760222", "reactome": "R-SCE-68688", "name": "CDC6 association with ORC(1-6) at replication origins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760214", "species_10760218" ], "products": [ "species_10760220" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P54791", "ORC4", "P54784", "phospho-ORC1", "P50874", "ORC5", "P54790", "ORC3", "P32833", "ORC2", "P54791", "ORC4", "P54784", "phospho-ORC1", "P09119", "CDC6", "P50874", "ORC5", "P54790", "ORC3" ] }, "reaction_10789311": { "compartment": "compartment_7660", "id": "reaction_10789311", "reactome": "R-SCE-9749253", "name": "Formation of MCM2-7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760361", "species_10760351" ], "products": [ "species_10760363" ], "modifiers": [], "additional_components": [ "P24279", "MCM3", "P29496", "MCM5", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29496", "MCM5" ] }, "reaction_10789365": { "compartment": "compartment_7660", "id": "reaction_10789365", "reactome": "R-SCE-9757257", "name": "MCM4, MCM6 and MCM7 form a heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760343", "species_10760347", "species_10760339" ], "products": [ "species_10760349" ], "modifiers": [], "additional_components": [ "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6" ] }, "reaction_10760210": { "compartment": "compartment_7660", "id": "reaction_10760210", "reactome": "R-SCE-68611", "name": "Formation of ORC(1-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760194", "species_10760204" ], "products": [ "species_10760208" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P54791", "ORC4", "P50874", "ORC5", "P54790", "ORC3", "P54784", "phospho-ORC1", "P32833", "ORC2", "P54791", "ORC4", "P54784", "phospho-ORC1", "P50874", "ORC5", "P54790", "ORC3" ] }, "reaction_10784856": { "compartment": "compartment_7660", "id": "reaction_10784856", "reactome": "R-SCE-6810376", "name": "ING2 binds PI5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776424", "species_6810408" ], "products": [ "species_10784854" ], "modifiers": [], "additional_components": [ "Q08465", "YOR064C", "P50947", "YNL097C", "P38806", "YHR090C", "Q08465", "YOR064C", "species_1806240", "P50947", "YNL097C", "P38806", "YHR090C" ] }, "reaction_10786979": { "compartment": "compartment_7660", "id": "reaction_10786979", "reactome": "R-SCE-8877692", "name": "PIN1 binds phosphorylated PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786972", "species_10771753" ], "products": [ "species_10786977" ], "modifiers": [], "additional_components": [ "P38994", "YDR208W", "YJR017C", "P38994", "YDR208W", "P22696", "YJR017C" ] }, "reaction_10786975": { "compartment": "compartment_7660", "id": "reaction_10786975", "reactome": "R-SCE-8877691", "name": "MAP2K6 phosphorylates PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10786961" ], "products": [ "species_113582", "species_10786972" ], "modifiers": [ [ "species_10770703", "catalyst" ] ], "additional_components": [ "P38994", "YDR208W", "P38994", "YDR208W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10764546": { "compartment": "compartment_70101", "id": "reaction_10764546", "reactome": "R-SCE-109702", "name": "PDPK1 phosphorylates AKT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10764531" ], "products": [ "species_29370", "species_10764543" ], "modifiers": [ [ "species_10764515", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10764517": { "compartment": "compartment_876", "id": "reaction_10764517", "reactome": "R-SCE-109701", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10764513" ], "products": [ "species_10764515" ], "modifiers": [], "additional_components": [ "YOL100W", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10772818": { "compartment": "compartment_70101", "id": "reaction_10772818", "reactome": "R-SCE-1358791", "name": "Phosphorylation of USP8 by P-AKT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772805", "species_113592" ], "products": [ "species_29370", "species_10772816" ], "modifiers": [ [ "species_10767105", "catalyst" ] ], "additional_components": [ "P39538", "YJL197W", "P32571", "YDR069C", "P39944", "YER144C", "P39538", "YJL197W", "P32571", "YDR069C", "P39944", "YER144C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10768224": { "compartment": "compartment_984", "id": "reaction_10768224", "reactome": "R-SCE-265456", "name": "NPC1L1 binds ezetimibe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265479", "species_10768220" ], "products": [ "species_10768222" ], "modifiers": [], "additional_components": [ "YPL006W", "species_265479", "Q12200", "YPL006W" ] }, "reaction_10777748": { "compartment": "compartment_70101", "id": "reaction_10777748", "reactome": "R-SCE-5362564", "name": "ADH1A,1C,4 oxidise atROL to atRAL in vitro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_73473", "species_975622" ], "modifiers": [ [ "species_10777745", "catalyst" ] ], "additional_components": [ "species_158417", "P32771", "YDL168W" ] }, "reaction_10777718": { "compartment": "compartment_70101", "id": "reaction_10777718", "reactome": "R-SCE-5362518", "name": "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_73473", "species_975622" ], "modifiers": [ [ "species_10777715", "catalyst" ] ], "additional_components": [ "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C" ] }, "reaction_10777743": { "compartment": "compartment_70101", "id": "reaction_10777743", "reactome": "R-SCE-5362522", "name": "ALDHs oxidise atRAL to atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975622", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_5334816" ], "modifiers": [ [ "species_10777740", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10777778": { "compartment": "compartment_70101", "id": "reaction_10777778", "reactome": "R-SCE-5419165", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_975622" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10777775", "catalyst" ] ], "additional_components": [ "P34251", "YNL181W", "Q08651", "YOR246C", "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C", "P53878", "YNL181W" ] }, "reaction_10784158": { "compartment": "compartment_7660", "id": "reaction_10784158", "reactome": "R-SCE-6802973", "name": "PLK3 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10763791" ], "products": [ "species_113582", "species_10784153" ], "modifiers": [ [ "species_10784155", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "YMR001C" ] }, "reaction_10766925": { "compartment": "compartment_876", "id": "reaction_10766925", "reactome": "R-SCE-196017", "name": "Dynamin is recruited to the gap junction plaque", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766678", "species_10766651" ], "products": [ "species_10766680" ], "modifiers": [], "additional_components": [ "P54861", "YLL001W", "P21576", "YKR001C", "P32266", "YOR211C", "P60010", "YFL039C", "P17891", "YGR167W", "Q99186", "YOL062C", "P22137", "YGL206C", "P60010", "YFL039C", "P54861", "YLL001W", "P17891", "YGR167W", "P21576", "YKR001C", "P32266", "YOR211C", "Q99186", "YOL062C", "P22137", "YGL206C" ] }, "reaction_10788439": { "compartment": "compartment_17947", "id": "reaction_10788439", "reactome": "R-SCE-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788429" ], "products": [ "species_10787654", "species_10788437" ], "modifiers": [], "additional_components": [ "P15202", "YDR256C", "P32573", "YNL202W", "P53112", "PEX14", "P32796", "YML042W", "P21954", "YDL066W", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P13711", "YGL205W", "Q12524", "YLR151C", "Q02207", "YKR009C", "P80667", "PEX13", "P16603", "YHR042W", "Q04370", "YMR026C", "Q06010", "YLR389C", "P31787", "YGR037C", "P39994", "YEL020C", "P00175", "CYB2", "P41903", "YJR019C", "P35056", "phospho-PEX5", "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "Q05568", "YDR265W", "P15202", "YDR256C", "P32573", "YNL202W", "P13711", "YGL205W", "Q12524", "YLR151C", "Q02207", "YKR009C", "P32796", "YML042W", "P21954", "YDL066W", "P16603", "YHR042W", "Q06010", "YLR389C", "P31787", "YGR037C", "P39994", "YEL020C", "P00175", "CYB2", "P41903", "YJR019C" ] }, "reaction_10788389": { "compartment": "compartment_70101", "id": "reaction_10788389", "reactome": "R-SCE-9033232", "name": "PEX7 binds cargo proteins containing PTS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788385", "species_10788379" ], "products": [ "species_10788387" ], "modifiers": [], "additional_components": [ "P47181", "YJR154W", "P27796", "YIL160C", "YDR142C", "P47181", "YJR154W", "P39108", "YDR142C", "P27796", "YIL160C" ] }, "reaction_10788486": { "compartment": "compartment_17947", "id": "reaction_10788486", "reactome": "R-SCE-9033527", "name": "PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788445", "species_10787658" ], "products": [ "species_10788447" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W" ] }, "reaction_10788441": { "compartment": "compartment_17947", "id": "reaction_10788441", "reactome": "R-SCE-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788427", "species_10788425" ], "products": [ "species_10788429" ], "modifiers": [], "additional_components": [ "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "Q05568", "YDR265W", "P15202", "YDR256C", "P32573", "YNL202W", "P32796", "YML042W", "P21954", "YDL066W", "P35056", "phospho-PEX5", "P13711", "YGL205W", "Q12524", "YLR151C", "Q02207", "YKR009C", "P16603", "YHR042W", "Q06010", "YLR389C", "P31787", "YGR037C", "P39994", "YEL020C", "P00175", "CYB2", "P41903", "YJR019C", "P15202", "YDR256C", "P32573", "YNL202W", "P53112", "PEX14", "P32796", "YML042W", "P21954", "YDL066W", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P13711", "YGL205W", "Q12524", "YLR151C", "Q02207", "YKR009C", "P80667", "PEX13", "P16603", "YHR042W", "Q04370", "YMR026C", "Q06010", "YLR389C", "P31787", "YGR037C", "P39994", "YEL020C", "P00175", "CYB2", "P41903", "YJR019C" ] }, "reaction_10788484": { "compartment": "compartment_17947", "id": "reaction_10788484", "reactome": "R-SCE-9033514", "name": "Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788476" ], "products": [ "species_10788445", "species_10788482" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P47181", "YJR154W", "P80667", "PEX13", "Q04370", "YMR026C", "P39108", "YDR142C", "P27796", "YIL160C", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W", "P47181", "YJR154W", "P27796", "YIL160C" ] }, "reaction_10788452": { "compartment": "compartment_17947", "id": "reaction_10788452", "reactome": "R-SCE-9033485", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788447" ], "products": [ "species_10772640", "species_10788449" ], "modifiers": [ [ "species_10788447", "catalyst" ] ], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W", "P15731", "YBR082C", "P15732", "YDR059C", "P35056", "phospho-PEX5", "P53112", "PEX14", "P05759", "RPS31", "P80667", "PEX13", "Q04370", "YMR026C", "P39108", "YDR142C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W" ] }, "reaction_10766513": { "compartment": "compartment_876", "id": "reaction_10766513", "reactome": "R-SCE-189242", "name": "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189246" ], "products": [ "species_189219" ], "modifiers": [ [ "species_10766510", "catalyst" ] ], "additional_components": [ "species_70113", "species_29532", "CHEBI:17118", "species_70113", "species_29532", "CHEBI:17118", "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10766502": { "compartment": "compartment_876", "id": "reaction_10766502", "reactome": "R-SCE-189222", "name": "SLC2A5 transports fructose from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189049" ], "products": [ "species_29532" ], "modifiers": [ [ "species_10766499", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10782658": { "compartment": "compartment_70101", "id": "reaction_10782658", "reactome": "R-SCE-6795290", "name": "TORC2 complex phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782648", "species_113592" ], "products": [ "species_29370", "species_10782656" ], "modifiers": [ [ "species_10767216", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "P11792", "YHR205W", "Q08236", "YOL078W", "P32600", "YKL203C", "P41318", "YNL006W", "P40061", "YER093C", "P38346", "YBR270C", "P47041", "YJL058C" ] }, "reaction_10782713": { "compartment": "compartment_7660", "id": "reaction_10782713", "reactome": "R-SCE-6797616", "name": "CCNK:CDK12 binds RNA Pol II at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782693", "species_10782677" ], "products": [ "species_10782695" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3", "Q03957", "YKL139W", "Q05949", "YLR226W", "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3" ] }, "reaction_10784265": { "compartment": "compartment_7660", "id": "reaction_10784265", "reactome": "R-SCE-6805640", "name": "AKT phosphorylates KAT6A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10775476" ], "products": [ "species_113582", "species_10784263" ], "modifiers": [ [ "species_10767347", "catalyst" ] ], "additional_components": [ "Q12311", "YPR031W", "Q08465", "YOR064C", "Q08649", "YOR244W", "P50947", "YNL097C", "P38806", "YHR090C", "P47128", "YJR082C", "Q12311", "YPR031W", "Q08649", "YOR244W", "Q08465", "YOR064C", "P50947", "YNL097C", "P38806", "YHR090C", "P47128", "YJR082C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10767160": { "compartment": "compartment_70101", "id": "reaction_10767160", "reactome": "R-SCE-198599", "name": "AKT phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10767147" ], "products": [ "species_29370", "species_10767157" ], "modifiers": [ [ "species_10767105", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10782671": { "compartment": "compartment_70101", "id": "reaction_10782671", "reactome": "R-SCE-6795473", "name": "PDPK1 phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10782656" ], "products": [ "species_29370", "species_10782666" ], "modifiers": [ [ "species_10764515", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "P11792", "YHR205W", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10784830": { "compartment": "compartment_7660", "id": "reaction_10784830", "reactome": "R-SCE-6810233", "name": "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784818", "species_29358" ], "products": [ "species_113582", "species_10784827" ], "modifiers": [ [ "species_10784818", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P53968", "YNL027W", "P04050", "YDL140C", "P32774", "YKL058W", "P13393", "SPT15", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P53968", "YNL027W", "P04050", "YDL140C", "P32774", "YKL058W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P53968", "YNL027W", "P04050", "YDL140C", "P32774", "YKL058W", "P13393", "SPT15", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C" ] }, "reaction_10784216": { "compartment": "compartment_7660", "id": "reaction_10784216", "reactome": "R-SCE-6804942", "name": "MDM2 homodimers auto-ubiquitinate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760537", "species_10784206" ], "products": [ "species_10784213" ], "modifiers": [ [ "species_10784206", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W" ] }, "reaction_10782642": { "compartment": "compartment_70101", "id": "reaction_10782642", "reactome": "R-SCE-6793666", "name": "MDM2 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767157" ], "products": [ "species_10768288" ], "modifiers": [], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W" ] }, "reaction_10782679": { "compartment": "compartment_7660", "id": "reaction_10782679", "reactome": "R-SCE-6797090", "name": "CCNK binds CDK12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782675", "species_10765011" ], "products": [ "species_10782677" ], "modifiers": [], "additional_components": [ "YKL139W", "YLR226W", "Q03957", "YKL139W", "Q05949", "YLR226W" ] }, "reaction_10784852": { "compartment": "compartment_7660", "id": "reaction_10784852", "reactome": "R-SCE-6810235", "name": "RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784835", "species_10784846", "species_10784844", "species_10784827" ], "products": [ "species_10784850" ], "modifiers": [], "additional_components": [ "YER139C", "YDR289C", "Q05543", "YDR289C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P53968", "YNL027W", "P04050", "YDL140C", "P32774", "YKL058W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P40084", "YER139C", "P53968", "YNL027W", "P04050", "YDL140C", "Q05543", "YDR289C", "P32774", "YKL058W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C" ] }, "reaction_10765625": { "compartment": "compartment_5460", "id": "reaction_10765625", "reactome": "R-SCE-163310", "name": "TFAM binds to mitochondrial promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163305", "species_10765621" ], "products": [ "species_10765623" ], "modifiers": [], "additional_components": [ "Q03435", "YDL002C", "Q02486", "YMR072W", "P33417", "YKL032C", "Q03973", "YDR174W", "P11633", "YBR089C-A", "Q03435", "YDL002C", "Q02486", "YMR072W", "P33417", "YKL032C", "Q03973", "YDR174W", "P11633", "YBR089C-A" ] }, "reaction_10782685": { "compartment": "compartment_7660", "id": "reaction_10782685", "reactome": "R-SCE-6797100", "name": "CCNK binds CDK13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782681", "species_10765011" ], "products": [ "species_10782683" ], "modifiers": [], "additional_components": [ "YKL139W", "YLR226W", "Q03957", "YKL139W", "Q05949", "YLR226W" ] }, "reaction_10782673": { "compartment": "compartment_70101", "id": "reaction_10782673", "reactome": "R-SCE-6795667", "name": "MDM2 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774893" ], "products": [ "species_10767147" ], "modifiers": [], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W" ] }, "reaction_10782640": { "compartment": "compartment_7660", "id": "reaction_10782640", "reactome": "R-SCE-6793661", "name": "(CDK1,CDK2):CCNA phosphorylates MDM2 at T218", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10768288" ], "products": [ "species_113582", "species_10782638" ], "modifiers": [ [ "species_10760454", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10782669": { "compartment": "compartment_70101", "id": "reaction_10782669", "reactome": "R-SCE-6795460", "name": "SGK1 phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10767147" ], "products": [ "species_29370", "species_10767157" ], "modifiers": [ [ "species_10782666", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10784258": { "compartment": "compartment_7660", "id": "reaction_10784258", "reactome": "R-SCE-6805061", "name": "CK2 binds FACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765099", "species_10784254" ], "products": [ "species_10784256" ], "modifiers": [], "additional_components": [ "P32558", "YGL207W", "Q04636", "YML069W", "P15790", "CKA1", "P38930", "CKB2", "P19454", "CKA2", "P15790", "CKA1", "P38930", "CKB2", "P32558", "YGL207W", "Q04636", "YML069W", "P19454", "CKA2" ] }, "reaction_10782711": { "compartment": "compartment_7660", "id": "reaction_10782711", "reactome": "R-SCE-6797606", "name": "CDK12 phosphorylates RNA Pol II CTD at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782695", "species_29358" ], "products": [ "species_113582", "species_10782708" ], "modifiers": [ [ "species_10782695", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3" ] }, "reaction_10770856": { "compartment": "compartment_7660", "id": "reaction_10770856", "reactome": "R-SCE-450550", "name": "PKCalpha phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770833", "species_29358" ], "products": [ "species_113582", "species_10770851" ], "modifiers": [ [ "species_10770853", "catalyst" ] ], "additional_components": [ "YDR429C", "YDR429C", "YBL105C" ] }, "reaction_10770848": { "compartment": "compartment_7660", "id": "reaction_10770848", "reactome": "R-SCE-450533", "name": "PKCdelta phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770833", "species_29358" ], "products": [ "species_113582", "species_10770843" ], "modifiers": [ [ "species_10770845", "catalyst" ] ], "additional_components": [ "YDR429C", "YDR429C", "YBL105C" ] }, "reaction_10771129": { "compartment": "compartment_7660", "id": "reaction_10771129", "reactome": "R-SCE-517705", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770843", "species_517622" ], "products": [ "species_10771127" ], "modifiers": [], "additional_components": [ "YDR429C", "Q04067", "YDR429C" ] }, "reaction_10771125": { "compartment": "compartment_7660", "id": "reaction_10771125", "reactome": "R-SCE-517674", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450605", "species_10770851" ], "products": [ "species_10771123" ], "modifiers": [], "additional_components": [ "YDR429C", "Q04067", "YDR429C" ] }, "reaction_10770837": { "compartment": "compartment_7660", "id": "reaction_10770837", "reactome": "R-SCE-450494", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770833", "species_450613" ], "products": [ "species_10770835" ], "modifiers": [], "additional_components": [ "YDR429C", "Q04067", "YDR429C" ] }, "reaction_10776322": { "compartment": "compartment_7660", "id": "reaction_10776322", "reactome": "R-SCE-3878123", "name": "Initiation of SAHF formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776313", "species_10776308", "species_10776318", "species_10776303" ], "products": [ "species_10776320" ], "modifiers": [], "additional_components": [ "YBR215W", "YBL008W", "YJR140C", "YJL115W", "Q01448", "YBR215W", "P32479", "YBL008W", "P32447", "YJL115W", "P47171", "YJR140C" ] }, "reaction_10771087": { "compartment": "compartment_876", "id": "reaction_10771087", "reactome": "R-SCE-507868", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10771084", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771099": { "compartment": "compartment_876", "id": "reaction_10771099", "reactome": "R-SCE-507873", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29514" ], "products": [ "species_432019" ], "modifiers": [ [ "species_10771096", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10770170": { "compartment": "compartment_876", "id": "reaction_10770170", "reactome": "R-SCE-432074", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10770167", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771101": { "compartment": "compartment_876", "id": "reaction_10771101", "reactome": "R-SCE-507875", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10771096", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771094": { "compartment": "compartment_876", "id": "reaction_10771094", "reactome": "R-SCE-507871", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10771084", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10770159": { "compartment": "compartment_876", "id": "reaction_10770159", "reactome": "R-SCE-432049", "name": "Aquaporin-9 passively transports glycerol into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10770156", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771092": { "compartment": "compartment_876", "id": "reaction_10771092", "reactome": "R-SCE-507870", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10771084", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771090": { "compartment": "compartment_876", "id": "reaction_10771090", "reactome": "R-SCE-507869", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10771084", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10772773": { "compartment": "compartment_876", "id": "reaction_10772773", "reactome": "R-SCE-1299338", "name": "Activation of TRESK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772770", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10772786": { "compartment": "compartment_876", "id": "reaction_10772786", "reactome": "R-SCE-1299359", "name": "Activation of TALK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772783", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10772753": { "compartment": "compartment_876", "id": "reaction_10772753", "reactome": "R-SCE-1299304", "name": "Activation of tandem pore domain in a weak inwardly rectifying K+ channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772750", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10772736": { "compartment": "compartment_876", "id": "reaction_10772736", "reactome": "R-SCE-1299297", "name": "Activation of THIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772733", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10787432": { "compartment": "compartment_13231", "id": "reaction_10787432", "reactome": "R-SCE-8944457", "name": "MAF1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787425" ], "products": [ "species_10787423" ], "modifiers": [], "additional_components": [ "YDR005C", "YDR005C" ] }, "reaction_10764398": { "compartment": "compartment_7660", "id": "reaction_10764398", "reactome": "R-SCE-77589", "name": "Recognition of AAUAAA sequence by CPSF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762363", "species_10764394" ], "products": [ "species_10764396" ], "modifiers": [], "additional_components": [ "Q01329", "YAL043C", "Q12102", "YLR115W", "P45976", "YJR093C", "P42841", "YNL317W", "Q06224", "YLR277C", "Q06102", "YPR107C", "Q06632", "YDR301W", "P34160", "YMR125W", "Q08920", "YPL178W", "P34160", "YMR125W", "Q01329", "YAL043C", "Q12102", "YLR115W", "P45976", "YJR093C", "P42841", "YNL317W", "Q06224", "YLR277C", "Q08920", "YPL178W", "Q06102", "YPR107C", "Q06632", "YDR301W" ] }, "reaction_10789005": { "compartment": "compartment_70101", "id": "reaction_10789005", "reactome": "R-SCE-9664883", "name": "ATM:PEX5 translocates from cytosol to peroxisomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788984" ], "products": [ "species_10788990" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P38110", "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10788897": { "compartment": "compartment_70101", "id": "reaction_10788897", "reactome": "R-SCE-9646348", "name": "PolyUb-Misfolded Proteins:HDAC6 bind dynein motor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788876", "species_10788893" ], "products": [ "species_10788895" ], "modifiers": [], "additional_components": [ "P05759", "RPS31", "P53973", "YNL021W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P0CE68", "YKR103W", "P12866", "YKL209C", "Q02647", "YDR424C", "P40960", "YDR488C", "P36022", "YKR054C", "P05759", "RPS31", "Q02647", "YDR424C", "P53973", "YNL021W", "P40960", "YDR488C", "P36022", "YKR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10788915": { "compartment": "compartment_18667", "id": "reaction_10788915", "reactome": "R-SCE-9646685", "name": "Aggresome dissociates from dynein and microtubule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788907" ], "products": [ "species_10768744", "species_10788913", "species_10788893" ], "modifiers": [], "additional_components": [ "P02557", "YFL037W", "P40960", "YDR488C", "P36022", "YKR054C", "species_29438", "P0CE68", "YKR103W", "species_29420", "P09734", "YML124C", "P05759", "RPS31", "P09733", "YML085C", "Q02647", "YDR424C", "P53973", "YNL021W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P12866", "YKL209C", "species_29420", "P09734", "YML124C", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "P05759", "RPS31", "P53973", "YNL021W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P0CE68", "YKR103W", "P12866", "YKL209C", "Q02647", "YDR424C", "P40960", "YDR488C", "P36022", "YKR054C" ] }, "reaction_10789014": { "compartment": "compartment_17947", "id": "reaction_10789014", "reactome": "R-SCE-9664888", "name": "ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788999" ], "products": [ "species_10789012" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P38110", "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10788869": { "compartment": "compartment_70101", "id": "reaction_10788869", "reactome": "R-SCE-9641127", "name": "Ub:misfolded proteins polymerize to PolyUb:misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788867" ], "products": [ "species_10788867" ], "modifiers": [], "additional_components": [ "P05759", "RPS31", "P53152", "MMS2", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52490", "UBC13", "P0CE68", "YKR103W", "P12866", "YKL209C", "P05759", "RPS31", "P53152", "MMS2", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52490", "UBC13", "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10789001": { "compartment": "compartment_17947", "id": "reaction_10789001", "reactome": "R-SCE-9664862", "name": "ATM dimer:PEX5 phosphorylates PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788992" ], "products": [ "species_10788999" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P38110", "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10788986": { "compartment": "compartment_70101", "id": "reaction_10788986", "reactome": "R-SCE-9664850", "name": "ATM binds PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788982", "species_10788423" ], "products": [ "species_10788984" ], "modifiers": [], "additional_components": [ "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10789003": { "compartment": "compartment_17947", "id": "reaction_10789003", "reactome": "R-SCE-9664879", "name": "ATM:PEX5 binds ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788990", "species_10788988" ], "products": [ "species_10788992" ], "modifiers": [ [ "species_1250243", "catalyst" ] ], "additional_components": [ "P35056", "phospho-PEX5", "P38110", "YBL088C", "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10763693": { "compartment": "compartment_17940", "id": "reaction_10763693", "reactome": "R-SCE-74723", "name": "Endosome acidification", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_74722" ], "modifiers": [ [ "species_10763690", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "P23968", "YHR026W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10779165": { "compartment": "compartment_7660", "id": "reaction_10779165", "reactome": "R-SCE-5682026", "name": "MRN bound to shortened telomeres activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779160" ], "products": [ "species_113582", "species_10779162", "species_10768327" ], "modifiers": [ [ "species_10779160", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10787738": { "compartment": "compartment_7660", "id": "reaction_10787738", "reactome": "R-SCE-8979071", "name": "KDM6B binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111793", "species_10775179" ], "products": [ "species_10775181" ], "modifiers": [], "additional_components": [ "YBR112C", "P14922", "YBR112C", "species_111793" ] }, "reaction_10775231": { "compartment": "compartment_7660", "id": "reaction_10775231", "reactome": "R-SCE-3239019", "name": "Active p38 MAPK phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10775221" ], "products": [ "species_113582", "species_10775228" ], "modifiers": [ [ "species_10775221", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W" ] }, "reaction_10775223": { "compartment": "compartment_7660", "id": "reaction_10775223", "reactome": "R-SCE-3238999", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10775219" ], "products": [ "species_113582", "species_10775221" ], "modifiers": [ [ "species_10770705", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10782617": { "compartment": "compartment_7660", "id": "reaction_10782617", "reactome": "R-SCE-6792712", "name": "KAT5 acetylates ATM at shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782614", "species_113560" ], "products": [ "species_2485002", "species_10779160" ], "modifiers": [ [ "species_10782614", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10775192": { "compartment": "compartment_70101", "id": "reaction_10775192", "reactome": "R-SCE-3228469", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770760", "species_113592" ], "products": [ "species_29370", "species_10770683" ], "modifiers": [ [ "species_10775189", "catalyst" ] ], "additional_components": [ "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C", "YLR362W" ] }, "reaction_10775184": { "compartment": "compartment_7660", "id": "reaction_10775184", "reactome": "R-SCE-3222593", "name": "KDM6B demethylates H3K27me3 on p16INK4A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775172", "species_113671" ], "products": [ "species_10775174", "species_159939" ], "modifiers": [ [ "species_10775181", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P14922", "YBR112C", "species_111793" ] }, "reaction_10771963": { "compartment": "compartment_70101", "id": "reaction_10771963", "reactome": "R-SCE-947591", "name": "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_947588", "species_29356" ], "products": [ "species_29370", "species_947594", "species_29372" ], "modifiers": [ [ "species_10771935", "catalyst" ] ], "additional_components": [ "species_33625", "species_1500581", "species_33625", "species_1500581", "P32660", "YER166W", "P39524", "YAL026C", "P40527", "YIL048W", "Q12675", "YDR093W", "Q12674", "YMR162C" ] }, "reaction_10777455": { "compartment": "compartment_70101", "id": "reaction_10777455", "reactome": "R-SCE-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_5252122" ], "products": [ "species_29370", "species_5252016", "species_29372" ], "modifiers": [ [ "species_10777450", "catalyst" ] ], "additional_components": [ "YOR291W" ] }, "reaction_10775325": { "compartment": "compartment_70101", "id": "reaction_10775325", "reactome": "R-SCE-3295579", "name": "TRPs transport extracellular Ca2+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10775312", "catalyst" ] ], "additional_components": [ "YOR087W" ] }, "reaction_10781096": { "compartment": "compartment_70101", "id": "reaction_10781096", "reactome": "R-SCE-5692462", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29418", "species_29356" ], "products": [ "species_29370", "species_29372", "species_1981162" ], "modifiers": [ [ "species_10781093", "catalyst" ] ], "additional_components": [ "YEL031W" ] }, "reaction_10771860": { "compartment": "compartment_20699", "id": "reaction_10771860", "reactome": "R-SCE-936883", "name": "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_113592", "species_29356" ], "products": [ "species_29370", "species_167012", "species_29372" ], "modifiers": [ [ "species_10771857", "catalyst" ] ], "additional_components": [ "species_109496", "P13586", "YGL167C" ] }, "reaction_10771868": { "compartment": "compartment_20699", "id": "reaction_10771868", "reactome": "R-SCE-936895", "name": "ATP7B transports cytosolic Cu2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_209799" ], "products": [ "species_29370", "species_936901", "species_29372" ], "modifiers": [ [ "species_10771865", "catalyst" ] ], "additional_components": [ "YDR270W" ] }, "reaction_10781101": { "compartment": "compartment_70101", "id": "reaction_10781101", "reactome": "R-SCE-5692480", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_5692450" ], "products": [ "species_29370", "species_29372", "species_5692484" ], "modifiers": [ [ "species_10781098", "catalyst" ] ], "additional_components": [ "YOR291W" ] }, "reaction_10774664": { "compartment": "compartment_70101", "id": "reaction_10774664", "reactome": "R-SCE-2684901", "name": "ANOs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10774659", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "YBR086C" ] }, "reaction_10789201": { "compartment": "compartment_70101", "id": "reaction_10789201", "reactome": "R-SCE-9701141", "name": "TRPV1 transports Ca2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10775312", "catalyst" ] ], "additional_components": [ "YOR087W" ] }, "reaction_10774674": { "compartment": "compartment_70101", "id": "reaction_10774674", "reactome": "R-SCE-2730692", "name": "CLCN4/5/6 exchange Cl- for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_2731008" ], "products": [ "species_352022", "species_74722" ], "modifiers": [ [ "species_10774669", "catalyst" ] ], "additional_components": [ "YJR040W" ] }, "reaction_10768792": { "compartment": "compartment_12045", "id": "reaction_10768792", "reactome": "R-SCE-381091", "name": "IRE1 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768784", "species_113592" ], "products": [ "species_29370", "species_10768789" ], "modifiers": [ [ "species_10768784", "catalyst" ] ], "additional_components": [ "P32361", "phospho-IRE1", "P32361", "phospho-IRE1", "P32361", "phospho-IRE1" ] }, "reaction_10768794": { "compartment": "compartment_12045", "id": "reaction_10768794", "reactome": "R-SCE-381109", "name": "IRE1 binds IRE1 forming dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768782" ], "products": [ "species_10768784" ], "modifiers": [], "additional_components": [ "P32361", "phospho-IRE1" ] }, "reaction_10770262": { "compartment": "compartment_12045", "id": "reaction_10770262", "reactome": "R-SCE-442393", "name": "ZIP7 mediates zinc efflux from the endoplasmic reticulum", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_442320" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10770259", "catalyst" ] ], "additional_components": [ "YIL023C" ] }, "reaction_10779105": { "compartment": "compartment_70101", "id": "reaction_10779105", "reactome": "R-SCE-5679206", "name": "MTMR14, MTMR3 dephosphorylate PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030" ], "products": [ "species_426639" ], "modifiers": [ [ "species_10773546", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10778999": { "compartment": "compartment_70101", "id": "reaction_10778999", "reactome": "R-SCE-5675868", "name": "ULK1 phosphorylates ATG13 and RB1CC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778709", "species_113592" ], "products": [ "species_29370", "species_10778996" ], "modifiers": [ [ "species_10778709", "catalyst" ] ], "additional_components": [ "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779119": { "compartment": "compartment_70101", "id": "reaction_10779119", "reactome": "R-SCE-5681980", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779063", "species_10779115" ], "products": [ "species_10779117" ], "modifiers": [], "additional_components": [ "YBR217W", "P38862", "YHR171W", "P38316", "YBR217W", "P38862", "YHR171W" ] }, "reaction_10778714": { "compartment": "compartment_70101", "id": "reaction_10778714", "reactome": "R-SCE-5672011", "name": "p-AMPK:AMP binds the ULK complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778630", "species_10768748" ], "products": [ "species_10778632" ], "modifiers": [], "additional_components": [ "P53104", "YGL180W", "Q06628", "YPR185W", "Q12527", "YPR049C", "P36002", "YKL198C", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "P36002", "YKL198C", "P34164", "YGL208W", "P53104", "YGL180W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "Q06628", "YPR185W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10788354": { "compartment": "compartment_70101", "id": "reaction_10788354", "reactome": "R-SCE-9020616", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779117" ], "products": [ "species_10779327" ], "modifiers": [], "additional_components": [ "P38316", "YBR217W", "P38862", "YHR171W", "P38316", "YBR217W", "P38862", "YHR171W" ] }, "reaction_10779133": { "compartment": "compartment_70101", "id": "reaction_10779133", "reactome": "R-SCE-5681981", "name": "ATG3 transfers LC3 from ATG7 to ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779128" ], "products": [ "species_10779130" ], "modifiers": [ [ "species_10779128", "catalyst" ] ], "additional_components": [ "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C", "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C", "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C" ] }, "reaction_10778727": { "compartment": "compartment_12045", "id": "reaction_10778727", "reactome": "R-SCE-5672012", "name": "Beclin-1 complex phosphorylates PtdIns", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_5676030", "species_29370" ], "modifiers": [ [ "species_10778724", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W" ] }, "reaction_10778646": { "compartment": "compartment_70101", "id": "reaction_10778646", "reactome": "R-SCE-5665868", "name": "AMPK (complex) phosphorylates ULK1 (complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778632", "species_113592" ], "products": [ "species_29370", "species_10778643" ], "modifiers": [ [ "species_10778632", "catalyst" ] ], "additional_components": [ "P36002", "YKL198C", "P34164", "YGL208W", "P53104", "YGL180W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "Q06628", "YPR185W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P34164", "YGL208W", "P53104", "YGL180W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "Q06628", "YPR185W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779026": { "compartment": "compartment_70101", "id": "reaction_10779026", "reactome": "R-SCE-5676229", "name": "WIPIs bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779022", "species_5693050" ], "products": [ "species_10779024" ], "modifiers": [], "additional_components": [ "Q02887", "YPL100W", "P43601", "YFR021W", "P50079", "YGR223C", "Q02887", "YPL100W", "P43601", "YFR021W", "species_1629751", "P50079", "YGR223C" ] }, "reaction_10778712": { "compartment": "compartment_70101", "id": "reaction_10778712", "reactome": "R-SCE-5672008", "name": "Thr-180 of ULK1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778643", "species_113592" ], "products": [ "species_29370", "species_10778709" ], "modifiers": [ [ "species_10778643", "catalyst" ] ], "additional_components": [ "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779077": { "compartment": "compartment_70101", "id": "reaction_10779077", "reactome": "R-SCE-5678490", "name": "ATG16L1 complex transfers LC3 from ATG3 to PE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5681998", "species_10779055" ], "products": [ "species_10779059", "species_10779057" ], "modifiers": [ [ "species_10779074", "catalyst" ] ], "additional_components": [ "P40344", "YNR007C", "P38182", "YBL078C", "YNR007C", "species_1500581", "P38182", "YBL078C", "species_6809774", "Q12380", "YPL149W", "P43601", "YFR021W", "P38316", "YBR217W" ] }, "reaction_10779143": { "compartment": "compartment_70101", "id": "reaction_10779143", "reactome": "R-SCE-5682011", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779041", "species_10779115" ], "products": [ "species_10779126" ], "modifiers": [], "additional_components": [ "YBL078C", "P38862", "YHR171W", "P38862", "YHR171W", "P38182", "YBL078C" ] }, "reaction_10779211": { "compartment": "compartment_5683628", "id": "reaction_10779211", "reactome": "R-SCE-5682388", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779057" ], "products": [ "species_10779202" ], "modifiers": [ [ "species_10779209", "catalyst" ], [ "species_10771366", "catalyst" ] ], "additional_components": [ "species_1500581", "P38182", "YBL078C", "species_1500581", "P38182", "YBL078C", "Q05919", "YLR360W", "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "Q04272", "YMR077C" ] }, "reaction_10779191": { "compartment": "compartment_12045", "id": "reaction_10779191", "reactome": "R-SCE-5682385", "name": "The phagophore extends from the PIP3-enriched structure", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778724" ], "products": [ "species_10779182" ], "modifiers": [ [ "species_10779187", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "YDL149W" ] }, "reaction_10779329": { "compartment": "compartment_70101", "id": "reaction_10779329", "reactome": "R-SCE-5682896", "name": "LC3:ATG7 dimer binds ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779059", "species_10779126" ], "products": [ "species_10779128" ], "modifiers": [], "additional_components": [ "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C", "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C" ] }, "reaction_10779107": { "compartment": "compartment_70101", "id": "reaction_10779107", "reactome": "R-SCE-5679239", "name": "ULK complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778996" ], "products": [ "species_10779099" ], "modifiers": [], "additional_components": [ "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779420": { "compartment": "compartment_70101", "id": "reaction_10779420", "reactome": "R-SCE-5683925", "name": "ULK1 is dephosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779418" ], "products": [ "species_10778630", "species_29372" ], "modifiers": [], "additional_components": [ "P53104", "YGL180W", "Q06628", "YPR185W", "Q12527", "YPR049C", "P53104", "YGL180W", "Q06628", "YPR185W", "Q12527", "YPR049C" ] }, "reaction_10779102": { "compartment": "compartment_70101", "id": "reaction_10779102", "reactome": "R-SCE-5679205", "name": "ULK1 phosphorylates Beclin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779087", "species_113592" ], "products": [ "species_29370", "species_10778724" ], "modifiers": [ [ "species_10779099", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779387": { "compartment": "compartment_70101", "id": "reaction_10779387", "reactome": "R-SCE-5683593", "name": "ATG7:ATG3:LC3 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779130" ], "products": [ "species_10779115", "species_10779055" ], "modifiers": [], "additional_components": [ "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C", "P38862", "YHR171W", "P40344", "YNR007C", "P38182", "YBL078C" ] }, "reaction_10779113": { "compartment": "compartment_70101", "id": "reaction_10779113", "reactome": "R-SCE-5679266", "name": "Beclin-1 complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779111" ], "products": [ "species_10779087" ], "modifiers": [], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W" ] }, "reaction_10769778": { "compartment": "compartment_17938", "id": "reaction_10769778", "reactome": "R-SCE-428007", "name": "Proton-coupled histidine and di-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427984", "species_428040" ], "products": [ "species_70106", "species_428003" ], "modifiers": [ [ "species_10769773", "catalyst" ] ], "additional_components": [ "CHEBI:90799", "CHEBI:32513", "CHEBI:32513", "CHEBI:46761", "YKR093W" ] }, "reaction_10787736": { "compartment": "compartment_70101", "id": "reaction_10787736", "reactome": "R-SCE-8959798", "name": "SLC30A10 transports Mn2+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29418" ], "products": [ "species_266099" ], "modifiers": [ [ "species_10787733", "catalyst" ] ], "additional_components": [ "P20107", "YMR243C", "P32798", "YOR316C" ] }, "reaction_10770232": { "compartment": "compartment_876", "id": "reaction_10770232", "reactome": "R-SCE-437300", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_437295" ], "products": [ "species_209799" ], "modifiers": [ [ "species_10770229", "catalyst" ] ], "additional_components": [ "YHR175W" ] }, "reaction_10770216": { "compartment": "compartment_876", "id": "reaction_10770216", "reactome": "R-SCE-435366", "name": "ZnT1 mediates the efflux of zinc from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_158417" ], "modifiers": [ [ "species_10770213", "catalyst" ] ], "additional_components": [ "YMR243C" ] }, "reaction_10770208": { "compartment": "compartment_876", "id": "reaction_10770208", "reactome": "R-SCE-434650", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_446589", "species_351626" ], "products": [ "species_70106", "species_446597" ], "modifiers": [ [ "species_10770205", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:16737", "LigandDisplayForward?ligandId=1231", "CHEBI:641", "CHEBI:6801", "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:16737", "LigandDisplayForward?ligandId=1231", "CHEBI:641", "CHEBI:6801", "P38767", "YHR032W", "Q05497", "YDR338C" ] }, "reaction_10769984": { "compartment": "compartment_876", "id": "reaction_10769984", "reactome": "R-SCE-429101", "name": "HMIT co-transports myo-inositol with a proton", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429130", "species_351626" ], "products": [ "species_70106", "species_426910" ], "modifiers": [ [ "species_10769981", "catalyst" ] ], "additional_components": [ "YDR497C" ] }, "reaction_10769870": { "compartment": "compartment_201753", "id": "reaction_10769870", "reactome": "R-SCE-428625", "name": "Vesicular inhibitory amino acid transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428548", "species_428592" ], "products": [ "species_70106", "species_428632" ], "modifiers": [ [ "species_10769867", "catalyst" ] ], "additional_components": [ "species_916850", "species_29424", "species_916850", "species_29424", "YJR001W" ] }, "reaction_10785998": { "compartment": "compartment_70101", "id": "reaction_10785998", "reactome": "R-SCE-8855062", "name": "SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162252", "species_71284" ], "products": [ "species_71285", "species_2162265" ], "modifiers": [ [ "species_10785995", "catalyst" ] ], "additional_components": [ "YNL003C" ] }, "reaction_10768477": { "compartment": "compartment_876", "id": "reaction_10768477", "reactome": "R-SCE-352158", "name": "SLC16A10-mediated uptake of aromatic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352161" ], "products": [ "species_352139" ], "modifiers": [ [ "species_10768474", "catalyst" ] ], "additional_components": [ "species_29502", "species_29500", "CHEBI:58315", "species_29502", "species_29500", "CHEBI:58315", "P25568", "YCL038C", "P53918", "YNL125C", "Q08777", "YOR306C", "Q08268", "YOL119C", "P36032", "YKL221W" ] }, "reaction_10778165": { "compartment": "compartment_70101", "id": "reaction_10778165", "reactome": "R-SCE-5627802", "name": "SLC26A4 transports I- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209785" ], "products": [ "species_209818" ], "modifiers": [ [ "species_10778162", "catalyst" ] ], "additional_components": [ "YPR003C" ] }, "reaction_10768673": { "compartment": "compartment_876", "id": "reaction_10768673", "reactome": "R-SCE-379432", "name": "SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29588", "species_379430" ], "products": [ "species_351964", "species_379440" ], "modifiers": [ [ "species_10768670", "catalyst" ] ], "additional_components": [ "species_379444", "species_1131871", "species_29468", "species_379444", "species_1131871", "species_29468", "P53341", "YGR292W", "P53051", "YGR287C", "P50276", "YGR055W", "P38734", "YHL036W", "P38158", "YBR299W", "P40884", "YJL216C", "P0CW41", "YJL221C", "P0CW40", "YIL172C", "Q08295", "YOL157C" ] }, "reaction_10769768": { "compartment": "compartment_876", "id": "reaction_10769768", "reactome": "R-SCE-427666", "name": "SLC26A3,6 exchange Cl- for HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111627", "species_188972" ], "products": [ "species_352022", "species_425425" ], "modifiers": [ [ "species_10769765", "catalyst" ] ], "additional_components": [ "P53394", "YPR003C" ] }, "reaction_10777542": { "compartment": "compartment_70101", "id": "reaction_10777542", "reactome": "R-SCE-5340130", "name": "CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5673778", "species_428040" ], "products": [ "species_70106", "species_379444" ], "modifiers": [ [ "species_10777539", "catalyst" ] ], "additional_components": [ "YCR075C" ] }, "reaction_10769759": { "compartment": "compartment_876", "id": "reaction_10769759", "reactome": "R-SCE-427570", "name": "Group 3 - Selective Cl- transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10769756", "catalyst" ] ], "additional_components": [ "P53394", "YPR003C" ] }, "reaction_10786838": { "compartment": "compartment_70101", "id": "reaction_10786838", "reactome": "R-SCE-8875871", "name": "SLC26A11 transports SO4(2-) from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648" ], "products": [ "species_174375" ], "modifiers": [ [ "species_10786835", "catalyst" ] ], "additional_components": [ "YBR294W" ] }, "reaction_10767238": { "compartment": "compartment_7660", "id": "reaction_10767238", "reactome": "R-SCE-198714", "name": "ERK5 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767234" ], "products": [ "species_10767236" ], "modifiers": [], "additional_components": [ "YPR054W", "YPR054W" ] }, "reaction_10778793": { "compartment": "compartment_70101", "id": "reaction_10778793", "reactome": "R-SCE-5674496", "name": "Activated MAPKs phosphorylate MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10778763" ], "products": [ "species_29370", "species_10778790" ], "modifiers": [ [ "species_10778780", "catalyst" ] ], "additional_components": [ "P06784", "YDL159W", "P06784", "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10779550": { "compartment": "compartment_7660", "id": "reaction_10779550", "reactome": "R-SCE-5687091", "name": "p-S MAPK6,4 binds MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775217", "species_10779544" ], "products": [ "species_10779548" ], "modifiers": [], "additional_components": [ "YKL171W", "YPR054W", "P41808", "YPR054W", "P36003", "YKL171W" ] }, "reaction_10780903": { "compartment": "compartment_70101", "id": "reaction_10780903", "reactome": "R-SCE-5690250", "name": "p-T182-MAPKAPK5 phoshphorylates DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10780891" ], "products": [ "species_29370", "species_10780900" ], "modifiers": [ [ "species_10780891", "catalyst" ] ], "additional_components": [ "P25294", "YNL007C", "P36003", "YKL171W", "P25294", "YNL007C", "P36003", "YKL171W", "P25294", "YNL007C", "P36003", "YKL171W" ] }, "reaction_10779572": { "compartment": "compartment_7660", "id": "reaction_10779572", "reactome": "R-SCE-5687109", "name": "MAPK4,6 translocate to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779563" ], "products": [ "species_10779557" ], "modifiers": [ [ "species_10779570", "catalyst" ] ], "additional_components": [ "P41808", "YPR054W", "P41808", "YPR054W", "YGR218W" ] }, "reaction_10779583": { "compartment": "compartment_7660", "id": "reaction_10779583", "reactome": "R-SCE-5687123", "name": "p-S115 MAPKAPK5 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779529" ], "products": [ "species_10779581" ], "modifiers": [], "additional_components": [ "YKL171W", "YKL171W" ] }, "reaction_10779542": { "compartment": "compartment_7660", "id": "reaction_10779542", "reactome": "R-SCE-5687088", "name": "PKA phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775217", "species_29358" ], "products": [ "species_113582", "species_10779529" ], "modifiers": [ [ "species_10779539", "catalyst" ] ], "additional_components": [ "YKL171W", "YKL171W", "P05986", "YKL166C", "P06245", "YPL203W", "P06244", "YJL164C" ] }, "reaction_10781177": { "compartment": "compartment_70101", "id": "reaction_10781177", "reactome": "R-SCE-5692770", "name": "SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781173", "species_10779577", "species_10779523" ], "products": [ "species_10781175" ], "modifiers": [], "additional_components": [ "P32457", "YLR314C", "Q07657", "YDL225W", "Q04921", "YDR218C", "P32468", "YHR107C", "P41901", "YGR059W", "P32458", "YJR076C", "YKL171W", "YPR054W", "P41808", "YPR054W", "P32457", "YLR314C", "Q07657", "YDL225W", "Q04921", "YDR218C", "P32468", "YHR107C", "P36003", "YKL171W", "P41901", "YGR059W", "P32458", "YJR076C" ] }, "reaction_10779565": { "compartment": "compartment_70101", "id": "reaction_10779565", "reactome": "R-SCE-5687107", "name": "MAPK4,6 translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779557" ], "products": [ "species_10779563" ], "modifiers": [], "additional_components": [ "P41808", "YPR054W", "P41808", "YPR054W" ] }, "reaction_10780893": { "compartment": "compartment_70101", "id": "reaction_10780893", "reactome": "R-SCE-5690245", "name": "p-T182 MAPKAPK5 binds DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779577", "species_10775708" ], "products": [ "species_10780891" ], "modifiers": [], "additional_components": [ "YKL171W", "YNL007C", "P25294", "YNL007C", "P36003", "YKL171W" ] }, "reaction_10779526": { "compartment": "compartment_70101", "id": "reaction_10779526", "reactome": "R-SCE-5687086", "name": "PAK1,2,3 phosphorylates MAPK6,4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779517", "species_113592" ], "products": [ "species_29370", "species_10779520" ], "modifiers": [ [ "species_10778157", "catalyst" ] ], "additional_components": [ "YPR054W", "YPR054W", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W" ] }, "reaction_10779575": { "compartment": "compartment_70101", "id": "reaction_10779575", "reactome": "R-SCE-5687112", "name": "MAPK6 is degraded by the 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779515" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "YPR054W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10781115": { "compartment": "compartment_7660", "id": "reaction_10781115", "reactome": "R-SCE-5692749", "name": "CDC14A,B bind MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781107", "species_10781109" ], "products": [ "species_10781113" ], "modifiers": [], "additional_components": [ "YPR054W", "YFR028C", "P41808", "YPR054W", "Q00684", "YFR028C" ] }, "reaction_10781120": { "compartment": "compartment_7660", "id": "reaction_10781120", "reactome": "R-SCE-5692754", "name": "CDC14A,B dephosphorylate p-3S,T MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10781113" ], "products": [ "species_113550", "species_10781117" ], "modifiers": [ [ "species_10781113", "catalyst" ] ], "additional_components": [ "P41808", "YPR054W", "Q00684", "YFR028C", "P41808", "YPR054W", "Q00684", "YFR028C", "P41808", "YPR054W", "Q00684", "YFR028C" ] }, "reaction_10779555": { "compartment": "compartment_7660", "id": "reaction_10779555", "reactome": "R-SCE-5687094", "name": "p-S MAPK6,4 phosphorylate MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779548" ], "products": [ "species_113582", "species_10779552" ], "modifiers": [ [ "species_10779548", "catalyst" ] ], "additional_components": [ "P41808", "YPR054W", "P36003", "YKL171W", "P41808", "YPR054W", "P36003", "YKL171W", "P41808", "YPR054W", "P36003", "YKL171W" ] }, "reaction_10779579": { "compartment": "compartment_7660", "id": "reaction_10779579", "reactome": "R-SCE-5687120", "name": "p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779552" ], "products": [ "species_10779577", "species_10779520" ], "modifiers": [], "additional_components": [ "P41808", "YPR054W", "P36003", "YKL171W", "YKL171W", "YPR054W" ] }, "reaction_10781140": { "compartment": "compartment_7660", "id": "reaction_10781140", "reactome": "R-SCE-5692764", "name": "MAPK6 binds CCND3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781136", "species_10779561" ], "products": [ "species_10781138" ], "modifiers": [ [ "species_10781109", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "YPR054W", "P13365", "YAL040C", "P20438", "YPL256C", "P41808", "YPR054W", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "YFR028C" ] }, "reaction_10770806": { "compartment": "compartment_70101", "id": "reaction_10770806", "reactome": "R-SCE-450463", "name": "MK2 phosphorylates ZFP36 (Tristetraproline, TTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770793", "species_113592" ], "products": [ "species_29370", "species_10770785" ], "modifiers": [ [ "species_10766447", "catalyst" ] ], "additional_components": [ "P47976", "YDR151C", "P38217", "YBR017C", "P47977", "YLR136C", "P47976", "YDR151C", "P38217", "YBR017C", "P47977", "YLR136C", "YKL171W" ] }, "reaction_10770831": { "compartment": "compartment_70101", "id": "reaction_10770831", "reactome": "R-SCE-450490", "name": "Protein Kinase B/Akt phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770810", "species_113592" ], "products": [ "species_29370", "species_10770828" ], "modifiers": [ [ "species_10767095", "catalyst" ] ], "additional_components": [ "P47976", "YDR151C", "P47976", "YDR151C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10770803": { "compartment": "compartment_70101", "id": "reaction_10770803", "reactome": "R-SCE-450431", "name": "ZFP36 (TTP) recruits RNA degradation activities", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770123", "species_10770057", "species_10770793", "species_10770799", "species_10770050" ], "products": [ "species_10770801" ], "modifiers": [], "additional_components": [ "P53859", "CSL4", "Q08285", "RRP40", "P53256", "RRP46", "P38792", "RRP4", "Q12277", "RRP42", "P48240", "MTR3", "Q08162", "DIS3", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "YNL118C", "P47976", "YDR151C", "P38217", "YBR017C", "P47977", "YLR136C", "YOL149W", "P47976", "YDR151C", "P53859", "CSL4", "Q08285", "RRP40", "P22147", "XRN1", "Q12277", "RRP42", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "P53550", "YNL118C", "P38217", "YBR017C", "P53256", "RRP46", "P38792", "RRP4", "P48240", "MTR3", "Q12517", "YOL149W", "Q08162", "DIS3", "P47977", "YLR136C" ] }, "reaction_10770824": { "compartment": "compartment_70101", "id": "reaction_10770824", "reactome": "R-SCE-450488", "name": "BRF1 Complex recruits RNA degradation activities", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770123", "species_10770810", "species_10770057", "species_10770799", "species_10770050" ], "products": [ "species_10770822" ], "modifiers": [], "additional_components": [ "P53859", "CSL4", "Q08285", "RRP40", "P53256", "RRP46", "P38792", "RRP4", "Q12277", "RRP42", "P48240", "MTR3", "Q08162", "DIS3", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "P47976", "YDR151C", "YNL118C", "YOL149W", "P47976", "YDR151C", "P53859", "CSL4", "Q08285", "RRP40", "P22147", "XRN1", "Q12277", "RRP42", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "P53550", "YNL118C", "P53256", "RRP46", "P38792", "RRP4", "P48240", "MTR3", "Q12517", "YOL149W", "Q08162", "DIS3" ] }, "reaction_10770795": { "compartment": "compartment_70101", "id": "reaction_10770795", "reactome": "R-SCE-450400", "name": "ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770791", "species_450597", "species_10770767" ], "products": [ "species_10770793" ], "modifiers": [], "additional_components": [ "P47976", "YDR151C", "P47977", "YLR136C", "YBR017C", "P47976", "YDR151C", "P38217", "YBR017C", "P47977", "YLR136C" ] }, "reaction_10770820": { "compartment": "compartment_70101", "id": "reaction_10770820", "reactome": "R-SCE-450474", "name": "MK2 phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770810", "species_113592" ], "products": [ "species_29370", "species_10770818" ], "modifiers": [ [ "species_10766447", "catalyst" ] ], "additional_components": [ "P47976", "YDR151C", "P47976", "YDR151C", "YKL171W" ] }, "reaction_10770839": { "compartment": "compartment_70101", "id": "reaction_10770839", "reactome": "R-SCE-450517", "name": "Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770808", "species_450523" ], "products": [ "species_10770810" ], "modifiers": [], "additional_components": [ "YDR151C", "P47976", "YDR151C" ] }, "reaction_10768801": { "compartment": "compartment_70101", "id": "reaction_10768801", "reactome": "R-SCE-381111", "name": "EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762638", "species_113592" ], "products": [ "species_29370", "species_10768798" ], "modifiers": [ [ "species_10768776", "catalyst" ] ], "additional_components": [ "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "P47042", "YJL057C" ] }, "reaction_10768778": { "compartment": "compartment_12045", "id": "reaction_10768778", "reactome": "R-SCE-381087", "name": "Dimerization of PERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768767" ], "products": [ "species_10768776" ], "modifiers": [], "additional_components": [ "YJL057C", "P47042", "YJL057C" ] }, "reaction_10771292": { "compartment": "compartment_70101", "id": "reaction_10771292", "reactome": "R-SCE-888592", "name": "Loading of GABA into clathrin sculpted GABA transport vesicle lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352011" ], "products": [ "species_428571" ], "modifiers": [ [ "species_10771289", "catalyst" ] ], "additional_components": [ "YJR001W" ] }, "reaction_10771287": { "compartment": "compartment_5460", "id": "reaction_10771287", "reactome": "R-SCE-888548", "name": "ALDH5A1 dehydrogenates SUCCSA to SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_880046", "species_113526" ], "products": [ "species_113536", "species_29362", "species_113529" ], "modifiers": [ [ "species_10771284", "catalyst" ] ], "additional_components": [ "P38067", "YBR006W" ] }, "reaction_10771335": { "compartment": "compartment_5460", "id": "reaction_10771335", "reactome": "R-SCE-916855", "name": "PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_916850" ], "products": [ "species_113552", "species_880046" ], "modifiers": [ [ "species_10771332", "catalyst" ] ], "additional_components": [ "CHEBI:33739", "P17649", "YGR019W" ] }, "reaction_10777469": { "compartment": "compartment_70101", "id": "reaction_10777469", "reactome": "R-SCE-5324632", "name": "Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777464", "species_5324631" ], "products": [ "species_10775732", "species_10775828", "species_10768212", "species_10777466" ], "modifiers": [ [ "species_10777464", "catalyst" ] ], "additional_components": [ "P02829", "YPL240C", "P53973", "YNL021W", "P28707", "YKL117W", "P38889", "YHR206W", "P10961", "YGL073W", "P15108", "YMR186W", "P25694", "YDL126C", "P38889", "YHR206W", "P10961", "YGL073W", "P02829", "YPL240C", "P15108", "YMR186W", "YKL117W", "P53973", "YNL021W", "P25694", "YDL126C", "P02829", "YPL240C", "P53973", "YNL021W", "P28707", "YKL117W", "P38889", "YHR206W", "P10961", "YGL073W", "P15108", "YMR186W", "P25694", "YDL126C" ] }, "reaction_10775838": { "compartment": "compartment_7660", "id": "reaction_10775838", "reactome": "R-SCE-3371518", "name": "SIRT1 binds to HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775800", "species_10769730" ], "products": [ "species_10775802" ], "modifiers": [], "additional_components": [ "P36016", "YKL073W", "P25294", "YNL007C", "P22202", "YER103W", "P38889", "YHR206W", "P10961", "YGL073W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "YDL042C", "P36016", "YKL073W", "P25294", "YNL007C", "P06700", "YDL042C", "P22202", "YER103W", "P38889", "YHR206W", "P10961", "YGL073W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C" ] }, "reaction_10776963": { "compartment": "compartment_7660", "id": "reaction_10776963", "reactome": "R-SCE-5082409", "name": "Dissociation of HSF1:HSP90 complex in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776961" ], "products": [ "species_10776953", "species_10776959", "species_10776931" ], "modifiers": [], "additional_components": [ "P02829", "YPL240C", "P28707", "YKL117W", "P38889", "YHR206W", "P10961", "YGL073W", "P15108", "YMR186W", "YKL117W", "P02829", "YPL240C", "P15108", "YMR186W", "P38889", "YHR206W", "P10961", "YGL073W" ] }, "reaction_10776071": { "compartment": "compartment_70101", "id": "reaction_10776071", "reactome": "R-SCE-3697860", "name": "SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776067", "species_10775367" ], "products": [ "species_10776069" ], "modifiers": [], "additional_components": [ "species_158417", "CHEBI:49552", "P40202", "CCS1", "species_158417", "P00445", "SOD1", "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1" ] }, "reaction_10776933": { "compartment": "compartment_7660", "id": "reaction_10776933", "reactome": "R-SCE-5082391", "name": "Trimerization of HSF1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776931" ], "products": [ "species_10775810" ], "modifiers": [], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W" ] }, "reaction_10787563": { "compartment": "compartment_70101", "id": "reaction_10787563", "reactome": "R-SCE-8951723", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776069" ], "products": [ "species_10775369" ], "modifiers": [], "additional_components": [ "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1", "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1" ] }, "reaction_10775817": { "compartment": "compartment_7660", "id": "reaction_10775817", "reactome": "R-SCE-3371467", "name": "SIRT1 deacetylates HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_427523", "species_10775802" ], "products": [ "species_427498", "species_427497", "species_10775814", "species_10769730" ], "modifiers": [ [ "species_10775802", "catalyst" ] ], "additional_components": [ "P36016", "YKL073W", "P25294", "YNL007C", "P06700", "YDL042C", "P22202", "YER103W", "P38889", "YHR206W", "P10961", "YGL073W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P36016", "YKL073W", "P25294", "YNL007C", "P22202", "YER103W", "P38889", "YHR206W", "P09435", "YBL075C", "P10592", "YLL024C", "P10961", "YGL073W", "P10591", "YAL005C", "YDL042C", "P36016", "YKL073W", "P25294", "YNL007C", "P06700", "YDL042C", "P22202", "YER103W", "P38889", "YHR206W", "P10961", "YGL073W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C" ] }, "reaction_10775358": { "compartment": "compartment_70101", "id": "reaction_10775358", "reactome": "R-SCE-3299691", "name": "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_1222424" ], "products": [ "species_29408", "species_29368" ], "modifiers": [ [ "species_10775355", "catalyst" ] ], "additional_components": [ "species_158417", "P00445", "SOD1", "species_437295" ] }, "reaction_10776951": { "compartment": "compartment_7660", "id": "reaction_10776951", "reactome": "R-SCE-5082405", "name": "Phosphorylation of HSF1 at Ser326 induces transactivation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775810", "species_29358" ], "products": [ "species_113582", "species_10776917" ], "modifiers": [ [ "species_10776948", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "P32600", "YKL203C", "P41318", "YNL006W", "P38873", "YHR186C" ] }, "reaction_10775376": { "compartment": "compartment_70101", "id": "reaction_10775376", "reactome": "R-SCE-3299753", "name": "CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775369" ], "products": [ "species_10775373", "species_10775355" ], "modifiers": [ [ "species_10775369", "catalyst" ] ], "additional_components": [ "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1", "species_158417", "CHEBI:49552", "P40202", "CCS1", "species_158417", "P00445", "SOD1", "species_437295", "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1" ] }, "reaction_10776841": { "compartment": "compartment_70101", "id": "reaction_10776841", "reactome": "R-SCE-4793911", "name": "MAPKAPK2 phosphorylates HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775732", "species_113592" ], "products": [ "species_29370", "species_10776838" ], "modifiers": [ [ "species_10766440", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "YKL171W" ] }, "reaction_10777933": { "compartment": "compartment_70101", "id": "reaction_10777933", "reactome": "R-SCE-5618107", "name": "ATP binding to HSP90 triggers conformation change", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10775834" ], "products": [ "species_10777927" ], "modifiers": [], "additional_components": [ "P36016", "YKL073W", "P02829", "YPL240C", "P22202", "YER103W", "species_29370", "P15705", "YOR027W", "P09435", "YBL075C", "P10592", "YLL024C", "P15108", "YMR186W", "P10591", "YAL005C", "P36016", "YKL073W", "P02829", "YPL240C", "P22202", "YER103W", "P15705", "YOR027W", "species_29370", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P15108", "YMR186W", "P10591", "YAL005C" ] }, "reaction_10788859": { "compartment": "compartment_17938", "id": "reaction_10788859", "reactome": "R-SCE-9640195", "name": "RRAGA,B hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788854" ], "products": [ "species_10788856", "species_29372" ], "modifiers": [ [ "species_10788854", "catalyst" ] ], "additional_components": [ "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P25378", "YCR027C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P25378", "YCR027C", "species_29438", "P38873", "YHR186C", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P32600", "YKL203C", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P25378", "YCR027C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10776883": { "compartment": "compartment_17963", "id": "reaction_10776883", "reactome": "R-SCE-4837364", "name": "Secretion of SOD3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776881" ], "products": [ "species_10775345" ], "modifiers": [], "additional_components": [ "species_158417", "P00445", "SOD1", "species_437295", "species_158417", "P00445", "SOD1", "species_437295" ] }, "reaction_10764183": { "compartment": "compartment_17951", "id": "reaction_10764183", "reactome": "R-SCE-76031", "name": "2 H2O2 => O2 + 2 H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113575" ], "products": [ "species_141343", "species_113535" ], "modifiers": [ [ "species_10764180", "catalyst" ] ], "additional_components": [ "P15202", "YDR256C", "species_189444", "species_113602" ] }, "reaction_10788844": { "compartment": "compartment_17938", "id": "reaction_10788844", "reactome": "R-SCE-9639286", "name": "RRAGC,D exchanges GTP for GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788837", "species_29420" ], "products": [ "species_29438", "species_10788841" ], "modifiers": [ [ "species_10788837", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10775629": { "compartment": "compartment_70616", "id": "reaction_10775629", "reactome": "R-SCE-3341294", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_10765569" ], "products": [ "species_10765567", "species_189461" ], "modifiers": [], "additional_components": [ "P00045", "YEL039C", "P00044", "YJR048W", "CHEBI:38574", "P00045", "YEL039C", "P00044", "YJR048W", "CHEBI:38573" ] }, "reaction_10788899": { "compartment": "compartment_17938", "id": "reaction_10788899", "reactome": "R-SCE-9646468", "name": "mTORC1 binds RHEB:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765837", "species_10788852" ], "products": [ "species_10788854" ], "modifiers": [], "additional_components": [ "P25378", "YCR027C", "species_29438", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P25378", "YCR027C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10775719": { "compartment": "compartment_70101", "id": "reaction_10775719", "reactome": "R-SCE-3371422", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775714" ], "products": [ "species_29372", "species_10775716" ], "modifiers": [ [ "species_10775714", "catalyst" ], [ "species_10775712", "catalyst" ] ], "additional_components": [ "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_29370", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W" ] }, "reaction_10776175": { "compartment": "compartment_17927", "id": "reaction_10776175", "reactome": "R-SCE-3777112", "name": "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_163953" ], "products": [ "species_189481", "species_189461" ], "modifiers": [ [ "species_10776172", "catalyst" ] ], "additional_components": [ "species_158417", "P00445", "SOD1", "species_437295" ] }, "reaction_10775836": { "compartment": "compartment_70101", "id": "reaction_10775836", "reactome": "R-SCE-3371503", "name": "STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775828", "species_10775822", "species_10775716" ], "products": [ "species_10775712", "species_10775834" ], "modifiers": [], "additional_components": [ "P02829", "YPL240C", "P15108", "YMR186W", "YOR027W", "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_29370", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P36016", "YKL073W", "P02829", "YPL240C", "P22202", "YER103W", "species_29370", "P15705", "YOR027W", "P09435", "YBL075C", "P10592", "YLL024C", "P15108", "YMR186W", "P10591", "YAL005C" ] }, "reaction_10775760": { "compartment": "compartment_70101", "id": "reaction_10775760", "reactome": "R-SCE-3371435", "name": "Constitutive phosphorylation by GSK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775732", "species_113592" ], "products": [ "species_29370", "species_10775740" ], "modifiers": [ [ "species_10775757", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "P50873", "YDL079C", "P38615", "YMR139W", "P21965", "YNL307C" ] }, "reaction_10775348": { "compartment": "compartment_984", "id": "reaction_10775348", "reactome": "R-SCE-3299682", "name": "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3299686", "species_351626" ], "products": [ "species_351629", "species_352327" ], "modifiers": [ [ "species_10775345", "catalyst" ] ], "additional_components": [ "species_158417", "P00445", "SOD1", "species_437295" ] }, "reaction_10775848": { "compartment": "compartment_70101", "id": "reaction_10775848", "reactome": "R-SCE-3371527", "name": "HSF1 trimer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775846" ], "products": [ "species_10775810" ], "modifiers": [], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W" ] }, "reaction_10775875": { "compartment": "compartment_70101", "id": "reaction_10775875", "reactome": "R-SCE-3371590", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775871", "species_10775873" ], "products": [ "species_10775714" ], "modifiers": [], "additional_components": [ "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P36016", "YKL073W", "P22202", "YER103W", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C" ] }, "reaction_10775865": { "compartment": "compartment_70101", "id": "reaction_10775865", "reactome": "R-SCE-3371531", "name": "Constitutive phosphorylation by pERK1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775732", "species_113592" ], "products": [ "species_29370", "species_10775856" ], "modifiers": [ [ "species_10775862", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10775869": { "compartment": "compartment_70101", "id": "reaction_10775869", "reactome": "R-SCE-3371586", "name": "Dissociation of cytosolic HSF1:HSP90 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775867" ], "products": [ "species_10775732", "species_10775828", "species_10768212" ], "modifiers": [], "additional_components": [ "P02829", "YPL240C", "P28707", "YKL117W", "P38889", "YHR206W", "P10961", "YGL073W", "P15108", "YMR186W", "P38889", "YHR206W", "P10961", "YGL073W", "P02829", "YPL240C", "P15108", "YMR186W", "YKL117W" ] }, "reaction_10788872": { "compartment": "compartment_17938", "id": "reaction_10788872", "reactome": "R-SCE-9645598", "name": "RRAGC,D hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788837" ], "products": [ "species_10788841", "species_29372" ], "modifiers": [ [ "species_10788837", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10776919": { "compartment": "compartment_7660", "id": "reaction_10776919", "reactome": "R-SCE-5082356", "name": "HSF1-mediated gene expression", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775812" ], "products": [ "species_10776897" ], "modifiers": [ [ "species_10776907", "catalyst" ], [ "species_10776917", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P25294", "YNL007C", "P02829", "YPL240C", "P10592", "YLL024C", "P15108", "YMR186W", "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W" ] }, "reaction_10788874": { "compartment": "compartment_17938", "id": "reaction_10788874", "reactome": "R-SCE-9645608", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788848", "species_10788850" ], "products": [ "species_10788852" ], "modifiers": [], "additional_components": [ "P32600", "YKL203C", "P41318", "YNL006W", "P38873", "YHR186C", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10775877": { "compartment": "compartment_70101", "id": "reaction_10775877", "reactome": "R-SCE-3371591", "name": "Trimerization of cytosolic HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775732" ], "products": [ "species_10775846" ], "modifiers": [ [ "species_10765400", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7" ] }, "reaction_10775337": { "compartment": "compartment_5460", "id": "reaction_10775337", "reactome": "R-SCE-3299680", "name": "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3299683", "species_113529" ], "products": [ "species_113533", "species_1614617" ], "modifiers": [ [ "species_10775334", "catalyst" ] ], "additional_components": [ "P00447", "YHR008C", "species_113527" ] }, "reaction_10775625": { "compartment": "compartment_5460", "id": "reaction_10775625", "reactome": "R-SCE-3323079", "name": "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_1655882", "species_113529" ], "products": [ "species_113563", "species_1655887" ], "modifiers": [ [ "species_10775622", "catalyst" ] ], "additional_components": [ "P41921", "YPL091W", "species_113596" ] }, "reaction_10769335": { "compartment": "compartment_70101", "id": "reaction_10769335", "reactome": "R-SCE-418456", "name": "cGMP is degraded by PDEs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30991" ], "products": [ "species_113578" ], "modifiers": [ [ "species_10769328", "catalyst" ] ], "additional_components": [ "YOR360C" ] }, "reaction_10788618": { "compartment": "compartment_70101", "id": "reaction_10788618", "reactome": "R-SCE-9610166", "name": "p-T,Y MAPK dimers translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775862" ], "products": [ "species_10767244" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10778778": { "compartment": "compartment_70101", "id": "reaction_10778778", "reactome": "R-SCE-5674385", "name": "p-T,Y MAPKs dimerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772586" ], "products": [ "species_10775862" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10788635": { "compartment": "compartment_7660", "id": "reaction_10788635", "reactome": "R-SCE-9612509", "name": "SGK phosphorylates SRF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10788623" ], "products": [ "species_113582", "species_10788626" ], "modifiers": [ [ "species_10788632", "catalyst" ] ], "additional_components": [ "YMR043W", "YMR043W", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10771748": { "compartment": "compartment_70101", "id": "reaction_10771748", "reactome": "R-SCE-927889", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771743", "species_113592" ], "products": [ "species_29370", "species_10771745" ], "modifiers": [ [ "species_10771743", "catalyst" ] ], "additional_components": [ "P10622", "YDL130W", "P38798", "YHR077C", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P38760", "YHR015W", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P12385", "SUP45", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P04147", "YER165W", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P39684", "YFR023W", "P38061", "RPL32", "P14120", "RPL30", "species_29420", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P39936", "YGL049C", "P0CX82", "RPL19A", "Q12099", "YDR021W", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P05453", "SUP35", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P48412", "YGR072W", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "Q08920", "YPL178W", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P30771", "YMR080C", "P34160", "YMR125W", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771730" ], "products": [ "species_10771693" ], "modifiers": [ [ "species_10771730", "catalyst" ] ], "additional_components": [ "P10622", "YDL130W", "P38798", "YHR077C", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "P40456", "YIL151C", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P17214", "YLR233C", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P38760", "YHR015W", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P12385", "SUP45", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P04147", "YER165W", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "Q03466", "YDR206W", "P39684", "YFR023W", "P38061", "RPL32", "P14120", "RPL30", "species_29420", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771633", "species_10771609" ], "products": [ "species_10771635" ], "modifiers": [], "additional_components": [ "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P38760", "YHR015W", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P12385", "SUP45", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P04147", "YER165W", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P39684", "YFR023W", "P38061", "RPL32", "P14120", "RPL30", "species_29420", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P39936", "YGL049C", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P05453", "SUP35", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "Q08920", "YPL178W", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P34160", "YMR125W", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B", "YMR080C", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P38760", "YHR015W", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P12385", "SUP45", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P04147", "YER165W", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P39684", "YFR023W", "P38061", "RPL32", "P14120", "RPL30", "species_29420", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P39936", "YGL049C", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P05453", "SUP35", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "Q08920", "YPL178W", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P30771", "YMR080C", "P34160", "YMR125W", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B" ] }, "reaction_10777503": { "compartment": "compartment_263163", "id": "reaction_10777503", "reactome": "R-SCE-5333658", "name": "CLAT:AP1:CLVS bind PI(3,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5334668", "species_10777499" ], "products": [ "species_10777501" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "Q12028", "YPR029C", "P22137", "YGL206C", "Q00776", "YPL259C", "P35181", "YLR170C", "species_6809774", "P17891", "YGR167W", "P36000", "YKL135C", "Q12028", "YPR029C", "P22137", "YGL206C", "Q00776", "YPL259C", "P35181", "YLR170C" ] }, "reaction_10764574": { "compartment": "compartment_70101", "id": "reaction_10764574", "reactome": "R-SCE-109857", "name": "MAP2K1 binds MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764553", "species_10764570" ], "products": [ "species_10764572" ], "modifiers": [], "additional_components": [ "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10764621": { "compartment": "compartment_70101", "id": "reaction_10764621", "reactome": "R-SCE-109863", "name": "Dissociation of p-T,Y-MAPK3:MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764600" ], "products": [ "species_10764553", "species_10764598" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10786323": { "compartment": "compartment_70101", "id": "reaction_10786323", "reactome": "R-SCE-8866275", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786276", "species_10786319" ], "products": [ "species_10786321" ], "modifiers": [], "additional_components": [ "YMR276W", "Q07872", "YLL038C", "Q05785", "YLR206W", "P34216", "YBL047C", "P39013", "YNL084C", "Q03769", "YDR153C", "P47160", "YJR125C", "P32521", "YIR006C", "Q12518", "YDL161W", "Q07872", "YLL038C", "Q05785", "YLR206W", "P34216", "YBL047C", "P39013", "YNL084C", "P48510", "YMR276W", "Q03769", "YDR153C", "P47160", "YJR125C", "P32521", "YIR006C", "Q12518", "YDL161W" ] }, "reaction_10786337": { "compartment": "compartment_876", "id": "reaction_10786337", "reactome": "R-SCE-8866277", "name": "AP-2 directly binds some endocytic cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786331", "species_10786030" ], "products": [ "species_10786333" ], "modifiers": [ [ "species_10786335", "inhibitor" ] ], "additional_components": [ "P0CE68", "YKR103W", "P12866", "YKL209C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "Q00381", "YJR058C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "P0CE68", "YKR103W", "Q00381", "YJR058C", "P12866", "YKL209C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "species_9648300", "Q00381", "YJR058C" ] }, "reaction_10786206": { "compartment": "compartment_70101", "id": "reaction_10786206", "reactome": "R-SCE-8863727", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781023", "species_10786204" ], "products": [ "species_10786190" ], "modifiers": [], "additional_components": [ "YDR139C", "Q99186", "YOL062C", "P38700", "YHL019C", "Q99186", "YOL062C", "P38700", "YHL019C" ] }, "reaction_10786140": { "compartment": "compartment_876", "id": "reaction_10786140", "reactome": "R-SCE-8856813", "name": "AAK1 phosphorylates AP-2 mu subunit at T156", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10786130" ], "products": [ "species_29370", "species_10786137" ], "modifiers": [ [ "species_10786130", "catalyst" ] ], "additional_components": [ "P25623", "YCR030C", "P17891", "YGR167W", "P53974", "YNL020C", "P36000", "YKL135C", "P34216", "YBL047C", "P38065", "YBL037W", "P38080", "YBR059C", "Q00381", "YJR058C", "Q05080", "YMR032W", "P39013", "YNL084C", "P27351", "YJR005W", "P43556", "YFL047W", "P22137", "YGL206C", "Q99186", "YOL062C", "P32521", "YIR006C", "P40494", "YIL095W", "species_179856", "P25623", "YCR030C", "P17891", "YGR167W", "P53974", "YNL020C", "P36000", "YKL135C", "P34216", "YBL047C", "P38065", "YBL037W", "P38080", "YBR059C", "Q00381", "YJR058C", "Q05080", "YMR032W", "P39013", "YNL084C", "P27351", "YJR005W", "P43556", "YFL047W", "P22137", "YGL206C", "Q99186", "YOL062C", "P32521", "YIR006C", "P40494", "YIL095W", "species_179856", "P25623", "YCR030C", "P17891", "YGR167W", "P53974", "YNL020C", "P36000", "YKL135C", "P34216", "YBL047C", "P38065", "YBL037W", "P38080", "YBR059C", "Q00381", "YJR058C", "Q05080", "YMR032W", "P39013", "YNL084C", "P27351", "YJR005W", "P43556", "YFL047W", "P22137", "YGL206C", "Q99186", "YOL062C", "P32521", "YIR006C", "P40494", "YIL095W", "species_179856" ] }, "reaction_10786527": { "compartment": "compartment_876", "id": "reaction_10786527", "reactome": "R-SCE-8868066", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10773422", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10786779": { "compartment": "compartment_876", "id": "reaction_10786779", "reactome": "R-SCE-8871196", "name": "Initial binding of AP-2 and clathrin to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769532", "species_179856", "species_10786030" ], "products": [ "species_10786116" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P22137", "YGL206C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "species_179856" ] }, "reaction_10786466": { "compartment": "compartment_876", "id": "reaction_10786466", "reactome": "R-SCE-8867613", "name": "PICALM binds R-SNAREs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786449", "species_10786462" ], "products": [ "species_10786464" ], "modifiers": [], "additional_components": [ "P33328", "YOR327C", "P31109", "YAL030W", "P38856", "YHR161C", "P53309", "YGR241C", "P38856", "YHR161C", "P53309", "YGR241C", "P33328", "YOR327C", "P31109", "YAL030W" ] }, "reaction_10789079": { "compartment": "compartment_70101", "id": "reaction_10789079", "reactome": "R-SCE-9681616", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9648300", "species_10786030" ], "products": [ "species_10786335" ], "modifiers": [], "additional_components": [ "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "Q00381", "YJR058C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "species_9648300", "Q00381", "YJR058C" ] }, "reaction_10786167": { "compartment": "compartment_876", "id": "reaction_10786167", "reactome": "R-SCE-8862280", "name": "FCHo proteins bind nascent clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786094", "species_10786063", "species_10786116", "species_10786110", "species_10786102", "species_10786124" ], "products": [ "species_10786126" ], "modifiers": [], "additional_components": [ "P25623", "YCR030C", "Q05080", "YMR032W", "P43556", "YFL047W", "P34216", "YBL047C", "P39013", "YNL084C", "P32521", "YIR006C", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "species_179856", "P34216", "YBL047C", "P39013", "YNL084C", "P32521", "YIR006C", "P34216", "YBL047C", "P39013", "YNL084C", "P32521", "YIR006C", "P25623", "YCR030C", "Q05080", "YMR032W", "P43556", "YFL047W", "P17891", "YGR167W", "P25623", "YCR030C", "P36000", "YKL135C", "P38065", "YBL037W", "P34216", "YBL047C", "Q00381", "YJR058C", "P27351", "YJR005W", "Q05080", "YMR032W", "P39013", "YNL084C", "P22137", "YGL206C", "Q99186", "YOL062C", "P43556", "YFL047W", "P32521", "YIR006C", "species_179856" ] }, "reaction_10765839": { "compartment": "compartment_17938", "id": "reaction_10765839", "reactome": "R-SCE-165195", "name": "GTP loading by Rheb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10765835" ], "products": [ "species_10765837", "species_29420" ], "modifiers": [], "additional_components": [ "species_29420", "P25378", "YCR027C", "P25378", "YCR027C", "species_29438" ] }, "reaction_10778419": { "compartment": "compartment_70101", "id": "reaction_10778419", "reactome": "R-SCE-5653957", "name": "Rag dimer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778402", "species_10778415" ], "products": [ "species_10778417" ], "modifiers": [], "additional_components": [ "Q00582", "YML121W", "species_29438", "species_29420", "P53290", "YGR163W", "species_29420", "P53290", "YGR163W", "Q00582", "YML121W", "species_29438" ] }, "reaction_10768750": { "compartment": "compartment_70101", "id": "reaction_10768750", "reactome": "R-SCE-380930", "name": "Phosphorylated AMPK binds AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767428", "species_76577" ], "products": [ "species_10768748" ], "modifiers": [], "additional_components": [ "P36002", "YKL198C", "P34164", "YGL208W", "Q04739", "YER027C", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "P36002", "YKL198C", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C" ] }, "reaction_10787858": { "compartment": "compartment_5460", "id": "reaction_10787858", "reactome": "R-SCE-8986181", "name": "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787850" ], "products": [], "modifiers": [ [ "species_10787855", "catalyst" ] ], "additional_components": [ "P53193", "JAC1", "P05150", "YJL088W", "Q07540", "YFH1", "P19882", "HSP60", "YDR430C" ] }, "reaction_10773966": { "compartment": "compartment_70616", "id": "reaction_10773966", "reactome": "R-SCE-1955380", "name": "TIMM9:TIMM10 transfers proteins to TIMM22", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773936", "species_10773958", "species_10773960" ], "products": [ "species_10773964" ], "modifiers": [], "additional_components": [ "P32897", "TIM23", "P18238", "YBR085W", "P18239", "YBL030C", "O74700", "TIM9", "P39515", "TIM17", "Q12328", "TIM22", "P87108", "TIM10", "Q06510", "TAZ1", "P04710", "AAC1", "P32897", "TIM23", "P18238", "YBR085W", "P18239", "YBL030C", "O74700", "TIM9", "P39515", "TIM17", "Q12328", "TIM22", "Q06510", "TAZ1", "P87108", "TIM10", "P04710", "AAC1" ] }, "reaction_10787754": { "compartment": "compartment_70101", "id": "reaction_10787754", "reactome": "R-SCE-8981553", "name": "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10787751", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10771210": { "compartment": "compartment_20699", "id": "reaction_10771210", "reactome": "R-SCE-742354", "name": "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756" ], "products": [ "species_914003" ], "modifiers": [ [ "species_10771207", "catalyst" ] ], "additional_components": [ "YEL004W" ] }, "reaction_10777534": { "compartment": "compartment_70101", "id": "reaction_10777534", "reactome": "R-SCE-5339538", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10777531", "catalyst" ] ], "additional_components": [ "P48439", "YOR085W", "Q03723", "YML019W" ] }, "reaction_10787772": { "compartment": "compartment_70101", "id": "reaction_10787772", "reactome": "R-SCE-8981574", "name": "GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10766510", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10777511": { "compartment": "compartment_70101", "id": "reaction_10777511", "reactome": "R-SCE-5336466", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29926" ], "products": [ "species_109496" ], "modifiers": [ [ "species_10777508", "catalyst" ] ], "additional_components": [ "YPL060W" ] }, "reaction_10770623": { "compartment": "compartment_70101", "id": "reaction_10770623", "reactome": "R-SCE-450092", "name": "GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770619" ], "products": [ "species_113592", "species_10770617" ], "modifiers": [], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C", "species_113592", "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10787104": { "compartment": "compartment_70101", "id": "reaction_10787104", "reactome": "R-SCE-8932851", "name": "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8932838" ], "products": [ "species_8932842" ], "modifiers": [ [ "species_10787101", "catalyst" ] ], "additional_components": [ "CHEBI:32513", "species_1131871", "species_29468", "CHEBI:32513", "species_1131871", "species_29468", "YOL092W" ] }, "reaction_10771591": { "compartment": "compartment_74700", "id": "reaction_10771591", "reactome": "R-SCE-917841", "name": "Acidification of Tf:TfR1 containing endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113592", "species_29356" ], "products": [ "species_29370", "species_74722", "species_29372" ], "modifiers": [ [ "species_10763690", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "P23968", "YHR026W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10771200": { "compartment": "compartment_20699", "id": "reaction_10771200", "reactome": "R-SCE-727759", "name": "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183" ], "products": [ "species_727753" ], "modifiers": [ [ "species_10771197", "catalyst" ] ], "additional_components": [ "YBR220C" ] }, "reaction_10770621": { "compartment": "compartment_70101", "id": "reaction_10770621", "reactome": "R-SCE-450088", "name": "GLUT1 tetramer binds 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10770617" ], "products": [ "species_10770619" ], "modifiers": [], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C", "P38142", "YBR241C", "P53142", "YGL104C", "species_113592" ] }, "reaction_10769976": { "compartment": "compartment_876", "id": "reaction_10769976", "reactome": "R-SCE-429036", "name": "SLC2A9 transports Fru, Glc, urate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429078" ], "products": [ "species_429148" ], "modifiers": [ [ "species_10769973", "catalyst" ] ], "additional_components": [ "species_70113", "species_29532", "CHEBI:17775", "species_70113", "species_29532", "CHEBI:17775", "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10771269": { "compartment": "compartment_876", "id": "reaction_10771269", "reactome": "R-SCE-879575", "name": "SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879603" ], "products": [ "species_879628" ], "modifiers": [ [ "species_10771266", "catalyst" ] ], "additional_components": [ "CHEBI:18332", "CHEBI:28774", "CHEBI:18332", "CHEBI:28774", "P25568", "YCL038C", "P53918", "YNL125C", "Q08777", "YOR306C", "Q08268", "YOL119C", "P36032", "YKL221W" ] }, "reaction_10777522": { "compartment": "compartment_70101", "id": "reaction_10777522", "reactome": "R-SCE-5339528", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10777519", "catalyst" ] ], "additional_components": [ "YOR085W" ] }, "reaction_10787770": { "compartment": "compartment_70101", "id": "reaction_10787770", "reactome": "R-SCE-8981570", "name": "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10787767", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10769950": { "compartment": "compartment_876", "id": "reaction_10769950", "reactome": "R-SCE-428779", "name": "GLUT7 and GLUT11 transport glucose and fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428819" ], "products": [ "species_428802" ], "modifiers": [ [ "species_10769947", "catalyst" ] ], "additional_components": [ "species_70113", "species_29532", "species_70113", "species_29532", "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10770626": { "compartment": "compartment_70101", "id": "reaction_10770626", "reactome": "R-SCE-450095", "name": "GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70113" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10766510", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10771213": { "compartment": "compartment_20699", "id": "reaction_10771213", "reactome": "R-SCE-742373", "name": "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742353" ], "products": [ "species_742361" ], "modifiers": [ [ "species_10771207", "catalyst" ] ], "additional_components": [ "YEL004W" ] }, "reaction_10787759": { "compartment": "compartment_70101", "id": "reaction_10787759", "reactome": "R-SCE-8981564", "name": "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10787756", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C" ] }, "reaction_10777514": { "compartment": "compartment_70101", "id": "reaction_10777514", "reactome": "R-SCE-5339524", "name": "GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10770617", "catalyst" ], [ "species_113592", "inhibitor" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10787519": { "compartment": "compartment_70616", "id": "reaction_10787519", "reactome": "R-SCE-8949688", "name": "SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8949220", "species_2889072" ], "products": [ "species_8949232", "species_2889083" ], "modifiers": [ [ "species_10787516", "catalyst" ] ], "additional_components": [ "YJR106W" ] }, "reaction_10764584": { "compartment": "compartment_70101", "id": "reaction_10764584", "reactome": "R-SCE-109858", "name": "MAP2K2 binds MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764580", "species_10764578" ], "products": [ "species_10764582" ], "modifiers": [], "additional_components": [ "YBL016W", "YDL159W", "P16892", "YBL016W", "P06784", "YDL159W" ] }, "reaction_10764623": { "compartment": "compartment_70101", "id": "reaction_10764623", "reactome": "R-SCE-109864", "name": "Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764616" ], "products": [ "species_10764578", "species_10764614" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "P06784", "YDL159W", "YDL159W", "YBL016W" ] }, "reaction_10788776": { "compartment": "compartment_70101", "id": "reaction_10788776", "reactome": "R-SCE-9635739", "name": "PTPN7 dephosphorylates p-T,Y-MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788755", "species_29356" ], "products": [ "species_10788773", "species_29372" ], "modifiers": [ [ "species_10788755", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "P25044", "YDL230W", "Q00772", "YHR030C", "P29461", "YOR208W", "P40048", "YER075C", "P14681", "YGR040W", "P16892", "YBL016W", "P25044", "YDL230W", "Q00772", "YHR030C", "P29461", "YOR208W", "P40048", "YER075C", "P14681", "YGR040W", "P16892", "YBL016W", "P25044", "YDL230W", "Q00772", "YHR030C", "P29461", "YOR208W", "P40048", "YER075C", "P14681", "YGR040W" ] }, "reaction_10778883": { "compartment": "compartment_70101", "id": "reaction_10778883", "reactome": "R-SCE-5675376", "name": "Cytosolic DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778780", "species_29356" ], "products": [ "species_10778842", "species_29372" ], "modifiers": [ [ "species_10778880", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P40479", "YIL113W", "P38590", "YNL053W" ] }, "reaction_10778786": { "compartment": "compartment_7660", "id": "reaction_10778786", "reactome": "R-SCE-5674387", "name": "Phosphorylated MAPKs translocate into the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778780" ], "products": [ "species_10778784" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10778836": { "compartment": "compartment_7660", "id": "reaction_10778836", "reactome": "R-SCE-5675373", "name": "Nuclear DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10778784" ], "products": [ "species_113550", "species_10778795" ], "modifiers": [ [ "species_10778833", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P40479", "YIL113W", "P38590", "YNL053W" ] }, "reaction_10788930": { "compartment": "compartment_876", "id": "reaction_10788930", "reactome": "R-SCE-9647991", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647934", "species_10767735" ], "products": [ "species_10788928" ], "modifiers": [], "additional_components": [ "Q12354", "YLR118C", "species_9647934", "Q12354", "YLR118C" ] }, "reaction_10778776": { "compartment": "compartment_20699", "id": "reaction_10778776", "reactome": "R-SCE-5674373", "name": "MAP2Ks phosphorylate MAPK at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778771", "species_113592" ], "products": [ "species_29370", "species_10778773" ], "modifiers": [ [ "species_10778771", "catalyst" ] ], "additional_components": [ "P06784", "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "P06784", "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10788926": { "compartment": "compartment_70101", "id": "reaction_10788926", "reactome": "R-SCE-9647987", "name": "FNTB inhibitors bind FNTA:FNTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9653479", "species_10788922" ], "products": [ "species_10788924" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=6531", "LigandDisplayForward?ligandId=8025", "LigandDisplayForward?ligandId=8024", "pubchem.compound:216453", "LigandDisplayForward?ligandId=8028", "LigandDisplayForward?ligandId=8026", "LigandDisplayForward?ligandId=8030", "P29703", "YKL019W", "P22007", "YDL090C", "LigandDisplayForward?ligandId=6531", "LigandDisplayForward?ligandId=8025", "P29703", "YKL019W", "LigandDisplayForward?ligandId=8024", "pubchem.compound:216453", "LigandDisplayForward?ligandId=8028", "LigandDisplayForward?ligandId=8026", "P22007", "YDL090C", "LigandDisplayForward?ligandId=8030" ] }, "reaction_10788778": { "compartment": "compartment_70101", "id": "reaction_10788778", "reactome": "R-SCE-9635743", "name": "PTPN7 binds p-T,Y-MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775862", "species_10788753" ], "products": [ "species_10788755" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P25044", "YDL230W", "P29461", "YOR208W", "P40048", "YER075C", "P16892", "YBL016W", "P25044", "YDL230W", "Q00772", "YHR030C", "P29461", "YOR208W", "P40048", "YER075C", "P14681", "YGR040W" ] }, "reaction_10785442": { "compartment": "compartment_20699", "id": "reaction_10785442", "reactome": "R-SCE-8848484", "name": "PLA2s hydrolyze phospholipids at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429785", "species_29356" ], "products": [ "species_6814303", "species_8848483" ], "modifiers": [ [ "species_10769964", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10785464": { "compartment": "compartment_20699", "id": "reaction_10785464", "reactome": "R-SCE-8849345", "name": "LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848483", "species_548819" ], "products": [ "species_76194", "species_429785" ], "modifiers": [ [ "species_10785461", "catalyst" ] ], "additional_components": [ "YOR298W" ] }, "reaction_10785255": { "compartment": "compartment_263163", "id": "reaction_10785255", "reactome": "R-SCE-6814676", "name": "SNAPs and NSF hexamer bind cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10785251" ], "products": [ "species_10785253" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "Q03322", "YDR468C", "P33328", "YOR327C", "Q04338", "YMR197C", "Q08144", "YOL018C", "Q03322", "YDR468C", "P33328", "YOR327C", "P18759", "YBR080C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P32602", "YBL050W" ] }, "reaction_10785195": { "compartment": "compartment_263163", "id": "reaction_10785195", "reactome": "R-SCE-6814088", "name": "SYS1 binds AcM-ARFRP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785165", "species_10785193" ], "products": [ "species_10785173" ], "modifiers": [], "additional_components": [ "YJL004C", "Q02804", "ARL3", "species_29438", "Q02804", "ARL3", "P41544", "YJL004C", "species_29438" ] }, "reaction_10785206": { "compartment": "compartment_263163", "id": "reaction_10785206", "reactome": "R-SCE-6814091", "name": "ARL1 recruits TGN Golgin homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785202", "species_10785187" ], "products": [ "species_10785204" ], "modifiers": [], "additional_components": [ "P47166", "YJR134C", "Q02804", "ARL3", "P38116", "YBR164C", "P41544", "YJL004C", "species_29438", "Q02804", "ARL3", "P38116", "YBR164C", "P47166", "YJR134C", "P41544", "YJL004C", "species_29438" ] }, "reaction_10785104": { "compartment": "compartment_263163", "id": "reaction_10785104", "reactome": "R-SCE-6811428", "name": "RIC1:RGP1 recruits RAB6:GDP to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785096", "species_10785084" ], "products": [ "species_10785102" ], "modifiers": [], "additional_components": [ "P16664", "YDR137W", "P40395", "YLR039C", "species_29420", "Q99260", "YLR262C", "species_29420", "P16664", "YDR137W", "Q99260", "YLR262C", "P40395", "YLR039C" ] }, "reaction_10785314": { "compartment": "compartment_263163", "id": "reaction_10785314", "reactome": "R-SCE-6814684", "name": "cis-SNARE binds SNAPs and NSF hexamer at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10785310" ], "products": [ "species_10785312" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "P31377", "YAL014C", "Q03322", "YDR468C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P31377", "YAL014C", "Q03322", "YDR468C", "P18759", "YBR080C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P32602", "YBL050W" ] }, "reaction_10785111": { "compartment": "compartment_263163", "id": "reaction_10785111", "reactome": "R-SCE-6811429", "name": "RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10785102" ], "products": [ "species_10785108", "species_29420" ], "modifiers": [ [ "species_10785102", "catalyst" ] ], "additional_components": [ "species_29420", "P16664", "YDR137W", "Q99260", "YLR262C", "P40395", "YLR039C", "P16664", "YDR137W", "Q99260", "YLR262C", "species_29438", "P40395", "YLR039C", "species_29420", "P16664", "YDR137W", "Q99260", "YLR262C", "P40395", "YLR039C" ] }, "reaction_10785189": { "compartment": "compartment_263163", "id": "reaction_10785189", "reactome": "R-SCE-6814086", "name": "ARFRP1 recruits ARL1 to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785173", "species_10785181" ], "products": [ "species_10785187" ], "modifiers": [], "additional_components": [ "Q02804", "ARL3", "P41544", "YJL004C", "species_29438", "P38116", "YBR164C", "species_29438", "Q02804", "ARL3", "P38116", "YBR164C", "P41544", "YJL004C", "species_29438" ] }, "reaction_10785258": { "compartment": "compartment_263163", "id": "reaction_10785258", "reactome": "R-SCE-6814678", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10785253" ], "products": [ "species_29370", "species_10785249", "species_10785245", "species_10769994", "species_10781444", "species_10785247", "species_10785240" ], "modifiers": [ [ "species_10785253", "catalyst" ] ], "additional_components": [ "Q03322", "YDR468C", "P33328", "YOR327C", "P18759", "YBR080C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P32602", "YBL050W", "YOR327C", "YOL018C", "YBL050W", "P18759", "YBR080C", "YMR197C", "YDR468C", "Q03322", "YDR468C", "P33328", "YOR327C", "P18759", "YBR080C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P32602", "YBL050W" ] }, "reaction_10768386": { "compartment": "compartment_70101", "id": "reaction_10768386", "reactome": "R-SCE-350769", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10768358" ], "products": [ "species_10768366", "species_29420" ], "modifiers": [ [ "species_10768383", "catalyst" ] ], "additional_components": [ "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "P11076", "YDL192W", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C" ] }, "reaction_10768579": { "compartment": "compartment_70101", "id": "reaction_10768579", "reactome": "R-SCE-376357", "name": "Vamp7 associated Lysosome to Plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768561", "species_10768567", "species_10768572" ], "products": [ "species_10768561", "species_10768567", "species_10768574" ], "modifiers": [ [ "species_10768576", "catalyst" ] ], "additional_components": [ "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "YLR093C", "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "YLR093C", "P40357", "YGR009C", "Q12255", "YLR093C", "P32867", "YPL232W", "Q04359", "YMR017W", "P39926", "YMR183C" ] }, "reaction_10768619": { "compartment": "compartment_876", "id": "reaction_10768619", "reactome": "R-SCE-376369", "name": "Vamp2 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768561", "species_10768567", "species_10768608" ], "products": [ "species_10768561", "species_10768567", "species_10768614" ], "modifiers": [ [ "species_10768616", "catalyst" ] ], "additional_components": [ "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "P33328", "YOR327C", "P31109", "YAL030W", "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "P33328", "YOR327C", "P31109", "YAL030W", "P40357", "YGR009C", "P32867", "YPL232W", "P33328", "YOR327C", "Q04359", "YMR017W", "P31109", "YAL030W", "P39926", "YMR183C" ] }, "reaction_10768602": { "compartment": "compartment_70101", "id": "reaction_10768602", "reactome": "R-SCE-376364", "name": "Vamp8 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768591", "species_10768561", "species_10768567" ], "products": [ "species_10768561", "species_10768597", "species_10768567" ], "modifiers": [ [ "species_10768599", "catalyst" ] ], "additional_components": [ "P33328", "YOR327C", "P31109", "YAL030W", "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "P40357", "YGR009C", "Q04359", "YMR017W", "P33328", "YOR327C", "P31109", "YAL030W", "P32867", "YPL232W", "P39926", "YMR183C", "P40357", "YGR009C", "P32867", "YPL232W", "P33328", "YOR327C", "Q04359", "YMR017W", "P31109", "YAL030W", "P39926", "YMR183C" ] }, "reaction_10776489": { "compartment": "compartment_7660", "id": "reaction_10776489", "reactome": "R-SCE-4411373", "name": "NLK translocates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776483" ], "products": [ "species_10776487" ], "modifiers": [], "additional_components": [ "P41808", "YPR054W", "P41808", "YPR054W" ] }, "reaction_10776538": { "compartment": "compartment_70101", "id": "reaction_10776538", "reactome": "R-SCE-4551465", "name": "Translocation of NFATC1:CaN:CaM to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776532" ], "products": [ "species_10776536" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C", "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C" ] }, "reaction_10771589": { "compartment": "compartment_70101", "id": "reaction_10771589", "reactome": "R-SCE-917700", "name": "MVB Vesicle Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771585", "species_10771366" ], "products": [ "species_10771444", "species_10771583" ], "modifiers": [], "additional_components": [ "Q06696", "YLR417W", "Q12483", "YPL002C", "P05759", "RPS31", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P47142", "YJR102C", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "Q04272", "YMR077C", "P36095", "YKL041W", "P05759", "RPS31", "P39929", "YLR025W", "Q03390", "YDR486C", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P36108", "YKL002W", "Q04272", "YMR077C", "Q06696", "YLR417W", "Q12483", "YPL002C", "P47142", "YJR102C" ] }, "reaction_10771539": { "compartment": "compartment_74700", "id": "reaction_10771539", "reactome": "R-SCE-917693", "name": "ESCRT Disassembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10771444" ], "products": [ "species_10771364", "species_29370", "species_10771520", "species_10771359", "species_10771350", "species_29372", "species_10771345", "species_10771340" ], "modifiers": [ [ "species_10771536", "catalyst" ] ], "additional_components": [ "P36095", "YKL041W", "P05759", "RPS31", "P39929", "YLR025W", "Q03390", "YDR486C", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P36108", "YKL002W", "Q04272", "YMR077C", "YDR486C", "P05759", "RPS31", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YMR077C", "YLR025W", "YKL041W", "YKL002W", "Q06263", "YLR181C", "Q03390", "YDR486C", "P52917", "YPR173C" ] }, "reaction_10771587": { "compartment": "compartment_70101", "id": "reaction_10771587", "reactome": "R-SCE-917696", "name": "Cargo Sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771566", "species_10771583" ], "products": [ "species_10771585", "species_10771564" ], "modifiers": [], "additional_components": [ "Q02767", "YPL065W", "P05759", "RPS31", "Q99176", "YLR119W", "P25604", "YCL008C", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q06696", "YLR417W", "Q12483", "YPL002C", "P47142", "YJR102C", "Q06696", "YLR417W", "Q12483", "YPL002C", "P05759", "RPS31", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P47142", "YJR102C", "Q02767", "YPL065W", "Q99176", "YLR119W", "P25604", "YCL008C" ] }, "reaction_10772483": { "compartment": "compartment_70101", "id": "reaction_10772483", "reactome": "R-SCE-984606", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772463" ], "products": [ "species_10772465" ], "modifiers": [], "additional_components": [ "YEL061C", "P27895", "YEL061C" ] }, "reaction_10774270": { "compartment": "compartment_70101", "id": "reaction_10774270", "reactome": "R-SCE-2219524", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767662", "species_179856" ], "products": [ "species_10774268" ], "modifiers": [], "additional_components": [ "YOL100W", "Q12236", "YOL100W", "species_179856" ] }, "reaction_10785347": { "compartment": "compartment_20699", "id": "reaction_10785347", "reactome": "R-SCE-8847637", "name": "NSF and SNAPs bind the cis-SNARE at the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10785343" ], "products": [ "species_10785345" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P43682", "YKL006C-A", "P38736", "YHL031C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W" ] }, "reaction_10785368": { "compartment": "compartment_20699", "id": "reaction_10785368", "reactome": "R-SCE-8847875", "name": "ARF1:GTP binds Golgin TRIP11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785364", "species_10773521" ], "products": [ "species_10785366" ], "modifiers": [], "additional_components": [ "Q12234", "YOR216C", "P11491", "YDR481C", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996", "Q12234", "YOR216C", "P11491", "YDR481C", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10785424": { "compartment": "compartment_20699", "id": "reaction_10785424", "reactome": "R-SCE-8847880", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785394", "species_10773521" ], "products": [ "species_10785422" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "Q06836", "YPR095C", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10785431": { "compartment": "compartment_20699", "id": "reaction_10785431", "reactome": "R-SCE-8847883", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785422" ], "products": [ "species_10785428" ], "modifiers": [ [ "species_10785422", "catalyst" ] ], "additional_components": [ "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "Q06836", "YPR095C", "P19146", "YDL137W", "CHEBI:15996", "species_29420", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "Q06836", "YPR095C", "P19146", "YDL137W", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "Q06836", "YPR095C", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10785350": { "compartment": "compartment_20699", "id": "reaction_10785350", "reactome": "R-SCE-8847638", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10785345" ], "products": [ "species_10784697", "species_29370", "species_10784688", "species_10784699", "species_10769994", "species_10781444", "species_10784683" ], "modifiers": [ [ "species_10785345", "catalyst" ] ], "additional_components": [ "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W", "P22804", "YIL004C", "P43682", "YKL006C-A", "YHL031C", "YLR026C", "YBL050W", "P18759", "YBR080C", "YKL196C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W" ] }, "reaction_10772494": { "compartment": "compartment_17906", "id": "reaction_10772494", "reactome": "R-SCE-992703", "name": "Mitofusins trans-interact linking mitochondria prior to fusion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772488" ], "products": [ "species_10772492" ], "modifiers": [], "additional_components": [ "YBR179C", "P38297", "YBR179C" ] }, "reaction_10772555": { "compartment": "compartment_74700", "id": "reaction_10772555", "reactome": "R-SCE-1011576", "name": "EHD proteins interact with Rabenosyn-5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772546", "species_10772551" ], "products": [ "species_10772553" ], "modifiers": [], "additional_components": [ "P32790", "YBL007C", "P36115", "YKR019C", "YDR323C", "P32790", "YBL007C", "P36115", "YKR019C", "P32609", "YDR323C" ] }, "reaction_10772520": { "compartment": "compartment_5460", "id": "reaction_10772520", "reactome": "R-SCE-1008248", "name": "Adenylate Kinase 3 is a GTP-AMP phosphotransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159448", "species_113573" ], "products": [ "species_113525", "species_113581" ], "modifiers": [ [ "species_10772517", "catalyst" ] ], "additional_components": [ "YER170W" ] }, "reaction_10772572": { "compartment": "compartment_70101", "id": "reaction_10772572", "reactome": "R-SCE-1011598", "name": "DOCKs bind to RhoGEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768888", "species_10772560" ], "products": [ "species_10772570" ], "modifiers": [], "additional_components": [ "YLR229C", "YLR422W", "Q06409", "YLR422W", "P19073", "YLR229C" ] }, "reaction_10772503": { "compartment": "compartment_70101", "id": "reaction_10772503", "reactome": "R-SCE-992708", "name": "Dual-specific AKAPs bind type I and II PKA regulatory subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764953", "species_10772499" ], "products": [ "species_10772501" ], "modifiers": [], "additional_components": [ "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "YOR301W", "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "Q08760", "YOR301W", "P06244", "YJL164C" ] }, "reaction_10771252": { "compartment": "compartment_70101", "id": "reaction_10771252", "reactome": "R-SCE-879459", "name": "F-actin capping protein is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771243", "species_10771248" ], "products": [ "species_10771250" ], "modifiers": [], "additional_components": [ "YKL007W", "YIL034C", "P28495", "YKL007W", "P13517", "YIL034C" ] } }, "collapsed_reaction_dictionary": { "reaction_10760997": { "compartment": "compartment_7660", "id": "reaction_10760997", "reactome": "R-SCE-69173", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68452" ], "products": [ "species_69172" ], "modifiers": [ [ "species_10760994", "catalyst" ] ], "additional_components": [ "YDL164C" ] }, "reaction_10760965": { "compartment": "compartment_7660", "id": "reaction_10760965", "reactome": "R-SCE-69127", "name": "Formation of the Flap Intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760961" ], "products": [ "species_10760963" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P15436", "POL3", "P10363", "YIR008C", "P46957", "YJR006W", "P15873", "YBR088C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P15436", "POL3", "P10363", "YIR008C", "P46957", "YJR006W", "P15873", "YBR088C", "P20457", "YKL045W" ] }, "reaction_10760977": { "compartment": "compartment_7660", "id": "reaction_10760977", "reactome": "R-SCE-69142", "name": "Recruitment of Dna2 endonuclease", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760969", "species_10760973" ], "products": [ "species_10760975" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P15436", "POL3", "P22336", "YAR007C", "P10363", "YIR008C", "P46957", "YJR006W", "P26754", "YNL312W", "P15873", "YBR088C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P15436", "POL3", "P22336", "YAR007C", "P10363", "YIR008C", "P46957", "YJR006W", "P26754", "YNL312W", "P15873", "YBR088C", "P38859", "DNA2", "P20457", "YKL045W" ] }, "reaction_10760989": { "compartment": "compartment_7660", "id": "reaction_10760989", "reactome": "R-SCE-69152", "name": "Removal of remaining Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760979" ], "products": [ "species_10760981" ], "modifiers": [ [ "species_10760986", "catalyst" ] ], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P15436", "POL3", "P10363", "YIR008C", "P46957", "YJR006W", "P15873", "YBR088C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P15436", "POL3", "P10363", "YIR008C", "P46957", "YJR006W", "P15873", "YBR088C", "P20457", "YKL045W", "YKL113C" ] }, "reaction_10763788": { "compartment": "compartment_350", "id": "reaction_10763788", "reactome": "R-SCE-74986", "name": "Elongation of pre-rRNA transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_74985" ], "products": [ "species_74985" ], "modifiers": [ [ "species_10763299", "catalyst" ], [ "species_10763786", "catalyst" ] ], "additional_components": [ "Q01080", "YNL248C", "P20434", "RPB5", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P46669", "YOR340C", "P07703", "RPC40", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "Q04673", "YLR005W", "P10964", "YOR341W", "Q00578", "YIL143C", "P20436", "RPB8", "Q03290", "YDR460W", "Q12004", "YPR056W", "P40992", "YJL025W", "Q02939", "YPL122C", "P32529", "YJR063W", "P40422", "RPC10", "P22139", "RPB10", "P22138", "YPR010C", "P06839", "RAD3", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10763301": { "compartment": "compartment_7660", "id": "reaction_10763301", "reactome": "R-SCE-73769", "name": "Loss of Rrn3 from RNA Polymerase I promoter escape complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763295" ], "products": [ "species_10763299", "species_10763212" ], "modifiers": [], "additional_components": [ "Q01080", "YNL248C", "P20434", "RPB5", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P46669", "YOR340C", "P07703", "RPC40", "P32776", "YDR311W", "P36070", "YKL125W", "P06242", "YDL108W", "P13393", "SPT15", "Q04673", "YLR005W", "P10964", "YOR341W", "Q00578", "YIL143C", "P20436", "RPB8", "Q03290", "YDR460W", "Q12004", "YPR056W", "P40992", "YJL025W", "Q02939", "YPL122C", "P32529", "YJR063W", "P40422", "RPC10", "P22139", "RPB10", "P22138", "YPR010C", "P06839", "RAD3", "Q01080", "YNL248C", "P20434", "RPB5", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P46669", "YOR340C", "P07703", "RPC40", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "Q04673", "YLR005W", "P10964", "YOR341W", "Q00578", "YIL143C", "P20436", "RPB8", "Q03290", "YDR460W", "Q12004", "YPR056W", "P40992", "YJL025W", "Q02939", "YPL122C", "P32529", "YJR063W", "P40422", "RPC10", "P22139", "RPB10", "P22138", "YPR010C", "P06839", "RAD3", "YKL125W" ] }, "reaction_10763216": { "compartment": "compartment_7660", "id": "reaction_10763216", "reactome": "R-SCE-73757", "name": "Binding of RRN3 to RNA Polymerase I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763207", "species_10763212" ], "products": [ "species_10763214" ], "modifiers": [], "additional_components": [ "P10964", "YOR341W", "Q01080", "YNL248C", "P20434", "RPB5", "P20436", "RPB8", "P20435", "RPO26", "P32529", "YJR063W", "P40422", "RPC10", "P46669", "YOR340C", "P07703", "RPC40", "P22139", "RPB10", "P22138", "YPR010C", "YKL125W", "P10964", "YOR341W", "Q01080", "YNL248C", "P20434", "RPB5", "P20436", "RPB8", "P20435", "RPO26", "P32529", "YJR063W", "P40422", "RPC10", "P46669", "YOR340C", "P07703", "RPC40", "P22139", "RPB10", "P22138", "YPR010C", "P36070", "YKL125W" ] }, "reaction_10760927": { "compartment": "compartment_7660", "id": "reaction_10760927", "reactome": "R-SCE-69053", "name": "RFC binding displaces Pol Alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760830", "species_10760923" ], "products": [ "species_10760925" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P40348", "YJR068W", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "P38121", "YBL035C", "P13382", "YNL102W", "P40348", "YJR068W", "P10363", "YIR008C", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P20457", "YKL045W", "P38629", "YNL290W" ] }, "reaction_10760938": { "compartment": "compartment_7660", "id": "reaction_10760938", "reactome": "R-SCE-69063", "name": "Loading of PCNA - Sliding Clamp Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10760925", "species_10760934" ], "products": [ "species_113582", "species_10760936" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P40348", "YJR068W", "P10363", "YIR008C", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P20457", "YKL045W", "P38629", "YNL290W", "P15873", "YBR088C", "P38121", "YBL035C", "P13382", "YNL102W", "P40348", "YJR068W", "P10363", "YIR008C", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P20457", "YKL045W", "P38629", "YNL290W" ] }, "reaction_10760942": { "compartment": "compartment_7660", "id": "reaction_10760942", "reactome": "R-SCE-69068", "name": "RFC dissociates after sliding clamp formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760936" ], "products": [ "species_10760940", "species_10760923" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P40348", "YJR068W", "P10363", "YIR008C", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P20457", "YKL045W", "P38629", "YNL290W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P15873", "YBR088C", "P20457", "YKL045W", "P40348", "YJR068W", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W" ] }, "reaction_10773145": { "compartment": "compartment_12045", "id": "reaction_10773145", "reactome": "R-SCE-1482856", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[5]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10773142", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10773130": { "compartment": "compartment_12045", "id": "reaction_10773130", "reactome": "R-SCE-1482827", "name": "PC is hydrolyzed to 2-acyl LPC by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_975614", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10772925": { "compartment": "compartment_12045", "id": "reaction_10772925", "reactome": "R-SCE-1482533", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_1500578" ], "products": [ "species_76194", "species_426925" ], "modifiers": [ [ "species_10772920", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10773122": { "compartment": "compartment_12045", "id": "reaction_10773122", "reactome": "R-SCE-1482816", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10772968": { "compartment": "compartment_12045", "id": "reaction_10772968", "reactome": "R-SCE-1482547", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_1500578" ], "products": [ "species_76194", "species_426925" ], "modifiers": [ [ "species_10772920", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10773151": { "compartment": "compartment_12045", "id": "reaction_10773151", "reactome": "R-SCE-1482862", "name": "PC is hydrolysed to 2-acyl LPC by PLA2[7]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_975614", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10774233": { "compartment": "compartment_7660", "id": "reaction_10774233", "reactome": "R-SCE-2172678", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10774226", "species_113685" ], "products": [ "species_159942", "species_10774230", "species_159939", "species_29478" ], "modifiers": [ [ "species_10774226", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "species_111793", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "species_111793", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "species_111793", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10777844": { "compartment": "compartment_876", "id": "reaction_10777844", "reactome": "R-SCE-5607734", "name": "PKC-delta translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777274", "species_112275" ], "products": [ "species_10777842" ], "modifiers": [], "additional_components": [ "YBL105C", "species_112275", "P24583", "YBL105C" ] }, "reaction_10774717": { "compartment": "compartment_70101", "id": "reaction_10774717", "reactome": "R-SCE-2730867", "name": "Translocation of CaN:CaM:NFAT to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774691" ], "products": [ "species_10774715" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C", "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C" ] }, "reaction_10777848": { "compartment": "compartment_876", "id": "reaction_10777848", "reactome": "R-SCE-5607746", "name": "PKC-delta is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777842" ], "products": [ "species_10777846" ], "modifiers": [], "additional_components": [ "species_112275", "P24583", "YBL105C", "species_112275", "P24583", "YBL105C" ] }, "reaction_10774719": { "compartment": "compartment_70101", "id": "reaction_10774719", "reactome": "R-SCE-2730872", "name": "Activation of Calcineurin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767628", "species_74016", "species_10773995" ], "products": [ "species_10774687" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_74016", "species_158417", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C", "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C" ] }, "reaction_10777840": { "compartment": "compartment_70101", "id": "reaction_10777840", "reactome": "R-SCE-5607721", "name": "Activation of NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769138" ], "products": [ "species_10769138" ], "modifiers": [], "additional_components": [ "YCR073C", "YCR073C" ] }, "reaction_10774165": { "compartment": "compartment_70101", "id": "reaction_10774165", "reactome": "R-SCE-2162078", "name": "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161185", "species_29360" ], "products": [ "species_70106", "species_73473", "species_2162081" ], "modifiers": [ [ "species_10762111", "catalyst" ] ], "additional_components": [ "species_158417", "P32771", "YDL168W" ] }, "reaction_10760457": { "compartment": "compartment_7660", "id": "reaction_10760457", "reactome": "R-SCE-68944", "name": "Orc1 is phosphorylated by cyclin A/CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760396", "species_29358" ], "products": [ "species_113582", "species_10760408", "species_10760404" ], "modifiers": [ [ "species_10760454", "catalyst" ] ], "additional_components": [ "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P32833", "ORC2", "P54791", "ORC4", "P30665", "MCM4", "P54784", "phospho-ORC1", "P09119", "CDC6", "P53091", "MCM6", "P50874", "ORC5", "P29496", "MCM5", "P54790", "ORC3", "P24279", "MCM3", "P29469", "MCM2", "P32833", "ORC2", "P38132", "MCM7", "P54791", "ORC4", "P30665", "MCM4", "P09119", "CDC6", "P53091", "MCM6", "P50874", "ORC5", "P29496", "MCM5", "P54790", "ORC3", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760888": { "compartment": "compartment_7660", "id": "reaction_10760888", "reactome": "R-SCE-69006", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760843" ], "products": [ "species_10760886" ], "modifiers": [], "additional_components": [] }, "reaction_10760562": { "compartment": "compartment_7660", "id": "reaction_10760562", "reactome": "R-SCE-68946", "name": "Phosphorylated Orc1 is ubiquitinated while still associated with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760404", "species_10760537" ], "products": [ "species_10760540" ], "modifiers": [ [ "species_10760559", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W" ] }, "reaction_10760828": { "compartment": "compartment_70101", "id": "reaction_10760828", "reactome": "R-SCE-68948", "name": "Ubiquitinated Orc1 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760564" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10760566": { "compartment": "compartment_7660", "id": "reaction_10760566", "reactome": "R-SCE-68947", "name": "Ubiquitinated Orc1 enters the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760540" ], "products": [ "species_10760564" ], "modifiers": [], "additional_components": [] }, "reaction_10760896": { "compartment": "compartment_7660", "id": "reaction_10760896", "reactome": "R-SCE-69019", "name": "Mcm4,6,7 trimer forms and associates with the replication fork", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760363" ], "products": [ "species_10760359", "species_10760355", "species_10760349", "species_10760335" ], "modifiers": [], "additional_components": [ "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29496", "MCM5", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6" ] }, "reaction_10760884": { "compartment": "compartment_7660", "id": "reaction_10760884", "reactome": "R-SCE-69005", "name": "Cdc6 protein is phosphorylated by CDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10760214" ], "products": [ "species_113582", "species_10760843" ], "modifiers": [ [ "species_10760881", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760894": { "compartment": "compartment_70101", "id": "reaction_10760894", "reactome": "R-SCE-69016", "name": "Ubiquitinated Cdc6 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760892" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P09119", "CDC6", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10765258": { "compartment": "compartment_70101", "id": "reaction_10765258", "reactome": "R-SCE-114553", "name": "Activation of conventional Protein Kinase C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_33625", "species_10765240", "species_114519" ], "products": [ "species_10765256" ], "modifiers": [ [ "species_114519", "catalyst" ] ], "additional_components": [ "YBL105C", "species_33625", "P24583", "YBL105C", "species_74016", "species_6797635" ] }, "reaction_10769689": { "compartment": "compartment_70101", "id": "reaction_10769689", "reactome": "R-SCE-426043", "name": "2-AG hydrolysis to arachidonate by MAGL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426030", "species_29356" ], "products": [ "species_70106", "species_76116", "species_422506" ], "modifiers": [ [ "species_10769686", "catalyst" ] ], "additional_components": [ "YKL094W" ] }, "reaction_10765269": { "compartment": "compartment_70101", "id": "reaction_10765269", "reactome": "R-SCE-114683", "name": "Phosphorylation of Platelet Sec-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765263", "species_113592" ], "products": [ "species_29370", "species_10765266" ], "modifiers": [ [ "species_10765256", "catalyst" ] ], "additional_components": [ "YDR164C", "YDR164C", "species_33625", "P24583", "YBL105C", "species_74016", "species_6797635" ] }, "reaction_10771032": { "compartment": "compartment_70101", "id": "reaction_10771032", "reactome": "R-SCE-482772", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771010" ], "products": [ "species_10771030" ], "modifiers": [], "additional_components": [ "P60010", "YFL039C", "P06787", "YBR109C", "P09734", "YML124C", "Q12311", "YPR031W", "P46680", "YMR092C", "P30619", "YDR164C", "P00445", "SOD1", "P09733", "YML085C", "P60010", "YFL039C", "P06787", "YBR109C", "P09734", "YML124C", "Q12311", "YPR031W", "P46680", "YMR092C", "P30619", "YDR164C", "P00445", "SOD1", "P09733", "YML085C" ] }, "reaction_10769954": { "compartment": "compartment_70101", "id": "reaction_10769954", "reactome": "R-SCE-428941", "name": "P2Y purinoceptor 1 activates MAP kinase p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10769952" ], "products": [ "species_29370", "species_10766455" ], "modifiers": [ [ "species_10764870", "catalyst" ] ], "additional_components": [ "YLR113W", "YLR113W", "species_29438", "P10823", "YER020W" ] }, "reaction_10768515": { "compartment": "compartment_70101", "id": "reaction_10768515", "reactome": "R-SCE-354173", "name": "Activation of Rap1 by cytosolic GEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10768483" ], "products": [ "species_10768481", "species_29420" ], "modifiers": [ [ "species_10768512", "catalyst" ] ], "additional_components": [ "species_29420", "P13856", "YGR152C", "species_29438", "P13856", "YGR152C", "P04821", "YLR310C", "species_74016", "species_6797635", "P07866", "YAL024C", "P25300", "YCR038C" ] }, "reaction_10765291": { "compartment": "compartment_70101", "id": "reaction_10765291", "reactome": "R-SCE-114684", "name": "Phosphorylation of Syntaxin-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765281", "species_113592" ], "products": [ "species_29370", "species_10765289" ], "modifiers": [ [ "species_10765256", "catalyst" ] ], "additional_components": [ "P32867", "YPL232W", "P39926", "YMR183C", "P32867", "YPL232W", "P39926", "YMR183C", "species_33625", "P24583", "YBL105C", "species_74016", "species_6797635" ] }, "reaction_10770963": { "compartment": "compartment_876", "id": "reaction_10770963", "reactome": "R-SCE-481009", "name": "Exocytosis of platelet dense granule content", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770957" ], "products": [ "species_10770961" ], "modifiers": [], "additional_components": [ "species_29372", "species_74016", "species_113592", "species_29370", "species_111294", "CHEBI:15996", "species_111349", "P06101", "YDR168W", "species_109496", "species_209914", "species_29420", "species_29372", "species_74016", "species_113592", "species_29370", "species_29438", "species_111294", "P06101", "YDR168W", "species_109496", "species_209914" ] }, "reaction_10769661": { "compartment": "compartment_70101", "id": "reaction_10769661", "reactome": "R-SCE-425861", "name": "Activation of Protein Kinase C novel isoforms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767110", "species_114519" ], "products": [ "species_10769659" ], "modifiers": [], "additional_components": [ "YBL105C", "P24583", "YBL105C", "species_6797635" ] }, "reaction_10770980": { "compartment": "compartment_876", "id": "reaction_10770980", "reactome": "R-SCE-481044", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770972" ], "products": [ "species_10770978" ], "modifiers": [], "additional_components": [ "P38626", "YIL043C", "P53858", "YNL233W", "P38626", "YIL043C", "P53858", "YNL233W" ] }, "reaction_10774272": { "compartment": "compartment_70101", "id": "reaction_10774272", "reactome": "R-SCE-2316429", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767662", "species_179838" ], "products": [ "species_10764515" ], "modifiers": [], "additional_components": [ "YOL100W", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10769967": { "compartment": "compartment_70101", "id": "reaction_10769967", "reactome": "R-SCE-428961", "name": "Phosphorylation of cPLA2 by MAPK p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10769964" ], "products": [ "species_29370", "species_10764905" ], "modifiers": [ [ "species_10766455", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "YLR113W" ] }, "reaction_10770950": { "compartment": "compartment_876", "id": "reaction_10770950", "reactome": "R-SCE-481007", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770940" ], "products": [ "species_10770948" ], "modifiers": [], "additional_components": [ "Q05541", "YDR288W", "Q04338", "YMR197C", "P38219", "YBR025C", "Q05541", "YDR288W", "Q04338", "YMR197C", "P38219", "YBR025C" ] }, "reaction_10781550": { "compartment": "compartment_876", "id": "reaction_10781550", "reactome": "R-SCE-5694462", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694509", "species_29356" ], "products": [ "species_70106", "species_76116", "species_422506" ], "modifiers": [ [ "species_10781547", "catalyst" ] ], "additional_components": [ "YBR204C" ] }, "reaction_10769989": { "compartment": "compartment_114584", "id": "reaction_10769989", "reactome": "R-SCE-429157", "name": "ABCC4 accumulation of dense granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29372", "species_114565" ], "modifiers": [ [ "species_10769986", "catalyst" ] ], "additional_components": [ "YKL209C" ] }, "reaction_10770278": { "compartment": "compartment_70101", "id": "reaction_10770278", "reactome": "R-SCE-442749", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10770270" ], "products": [ "species_113582", "species_10770275" ], "modifiers": [ [ "species_10770270", "catalyst" ] ], "additional_components": [ "P06787", "YBR109C", "P43637", "YGL179C", "species_74016", "P06787", "YBR109C", "P43637", "YGL179C", "species_74016", "P06787", "YBR109C", "P43637", "YGL179C", "species_74016" ] }, "reaction_10789297": { "compartment": "compartment_70101", "id": "reaction_10789297", "reactome": "R-SCE-9748957", "name": "GMPS dimer transforms 6TXMP to 6TGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29356", "species_9748959" ], "products": [ "species_70106", "species_9748970", "species_29404", "species_111294", "species_76577" ], "modifiers": [ [ "species_10789294", "catalyst" ] ], "additional_components": [ "P38625", "YMR217W" ] }, "reaction_10789292": { "compartment": "compartment_70101", "id": "reaction_10789292", "reactome": "R-SCE-9748949", "name": "GUK1 phosphorylates 6TGMP to 6TGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9748970", "species_113592" ], "products": [ "species_29370", "species_9748960" ], "modifiers": [ [ "species_10763306", "catalyst" ] ], "additional_components": [ "YDR454C" ] }, "reaction_10766344": { "compartment": "compartment_17957", "id": "reaction_10766344", "reactome": "R-SCE-174931", "name": "UGTs transfer GlcA from UDP-GlcA to O-centre substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174384", "species_174911" ], "products": [ "species_158602", "species_174914" ], "modifiers": [ [ "species_10765441", "catalyst" ] ], "additional_components": [ "CHEBI:16580", "CHEBI:34665", "CHEBI:15882", "species_9749790", "CHEBI:46195", "CHEBI:32649", "species_158604", "CHEBI:65137", "CHEBI:176976", "CHEBI:64681", "YLR189C" ] }, "reaction_10789324": { "compartment": "compartment_70101", "id": "reaction_10789324", "reactome": "R-SCE-9751024", "name": "SLC29A1,2 transport 6MP from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9751015" ], "products": [ "species_9748998" ], "modifiers": [ [ "species_10764480", "catalyst" ] ], "additional_components": [ "YAL022C" ] }, "reaction_10789290": { "compartment": "compartment_70101", "id": "reaction_10789290", "reactome": "R-SCE-9748945", "name": "IMPDH tetramers dehydrogenate 6TIMP to 6TXMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9748992", "species_29360", "species_29356" ], "products": [ "species_73473", "species_70106", "species_9748959" ], "modifiers": [ [ "species_10763342", "catalyst" ] ], "additional_components": [ "P38697", "YHR216W", "P50095", "YLR432W", "P50094", "YML056C" ] }, "reaction_10789337": { "compartment": "compartment_70101", "id": "reaction_10789337", "reactome": "R-SCE-9753284", "name": "ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9753629", "species_29356" ], "products": [ "species_29370", "species_9753624", "species_29372" ], "modifiers": [ [ "species_10789334", "catalyst" ] ], "additional_components": [ "CHEBI:133438", "species_9753653", "CHEBI:133066", "CHEBI:133435", "P39109", "YDR135C", "P12866", "YKL209C" ] }, "reaction_10789314": { "compartment": "compartment_17957", "id": "reaction_10789314", "reactome": "R-SCE-9749977", "name": "UGT1A6 glucuronates ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9749790", "species_174384" ], "products": [ "species_158602", "species_9749997" ], "modifiers": [ [ "species_10765443", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10789299": { "compartment": "compartment_70101", "id": "reaction_10789299", "reactome": "R-SCE-9748963", "name": "GUK1 phosphorylates 6TdGMP to 6TdGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9749031", "species_113592" ], "products": [ "species_29370", "species_9749033" ], "modifiers": [ [ "species_10763306", "catalyst" ] ], "additional_components": [ "YDR454C" ] }, "reaction_10789332": { "compartment": "compartment_70101", "id": "reaction_10789332", "reactome": "R-SCE-9753283", "name": "ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_9753559" ], "products": [ "species_29370", "species_9753562", "species_29372" ], "modifiers": [ [ "species_10789329", "catalyst" ] ], "additional_components": [ "CHEBI:32635", "species_158604", "CHEBI:32636", "CHEBI:32635", "P53049", "YGR281W", "P12866", "YKL209C" ] }, "reaction_10789327": { "compartment": "compartment_70101", "id": "reaction_10789327", "reactome": "R-SCE-9753278", "name": "ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_9753559" ], "products": [ "species_29370", "species_9753562", "species_29372" ], "modifiers": [ [ "species_10772886", "catalyst" ] ], "additional_components": [ "CHEBI:32635", "species_158604", "CHEBI:32636", "CHEBI:32635", "P14772", "YLL015W", "P39109", "YDR135C", "P32386", "YLL048C", "P38735", "YHL035C" ] }, "reaction_10789339": { "compartment": "compartment_70101", "id": "reaction_10789339", "reactome": "R-SCE-9753632", "name": "CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9753680", "species_29356" ], "products": [ "species_9753653", "species_29424" ], "modifiers": [ [ "species_10772689", "catalyst" ] ], "additional_components": [ "species_113527", "P43616", "YFR044C" ] }, "reaction_10765448": { "compartment": "compartment_70101", "id": "reaction_10765448", "reactome": "R-SCE-158546", "name": "UGTs glucuronate APAP to APAP-GlcA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158601", "species_9677362" ], "products": [ "species_110096", "species_158604" ], "modifiers": [ [ "species_10765441", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10789301": { "compartment": "compartment_70101", "id": "reaction_10789301", "reactome": "R-SCE-9748969", "name": "NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9749033" ], "products": [ "species_29370", "species_9749032" ], "modifiers": [ [ "species_10770987", "catalyst" ] ], "additional_components": [ "P36010", "YKL067W" ] }, "reaction_10789303": { "compartment": "compartment_70101", "id": "reaction_10789303", "reactome": "R-SCE-9748999", "name": "NME1:2 hexamer phosphorylates 6TGDP to 6TGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9748960" ], "products": [ "species_29370", "species_9748947" ], "modifiers": [ [ "species_10770987", "catalyst" ] ], "additional_components": [ "P36010", "YKL067W" ] }, "reaction_10789322": { "compartment": "compartment_70101", "id": "reaction_10789322", "reactome": "R-SCE-9750656", "name": "ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9750692", "species_113592", "species_29356" ], "products": [ "species_29370", "species_9750678", "species_29372" ], "modifiers": [ [ "species_10789319", "catalyst" ] ], "additional_components": [ "CHEBI:9008", "CHEBI:58044", "CHEBI:88742", "CHEBI:176976", "CHEBI:36654", "species_9749997", "CHEBI:9008", "CHEBI:58044", "CHEBI:88742", "CHEBI:176976", "CHEBI:36654", "species_9749997", "P14772", "YLL015W", "P39109", "YDR135C", "P32386", "YLL048C", "P38735", "YHL035C", "P53049", "YGR281W" ] }, "reaction_10789317": { "compartment": "compartment_70101", "id": "reaction_10789317", "reactome": "R-SCE-9750546", "name": "ABCC4 transports TPMP substrates from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9750587", "species_113592", "species_29356" ], "products": [ "species_29370", "species_9750548", "species_29372" ], "modifiers": [ [ "species_10772888", "catalyst" ] ], "additional_components": [ "species_9748992", "species_9748970", "pubchem.compound:3037883", "CHEBI:80613", "pubchem.compound:3037883", "CHEBI:2332", "YKL209C" ] }, "reaction_10789341": { "compartment": "compartment_876", "id": "reaction_10789341", "reactome": "R-SCE-9753634", "name": "GGT dimers hydrolyse APAP-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9753685", "species_29356" ], "products": [ "species_9753680", "species_29404" ], "modifiers": [ [ "species_10777790", "catalyst" ] ], "additional_components": [ "Q05902", "YLR299W" ] }, "reaction_10781056": { "compartment": "compartment_7660", "id": "reaction_10781056", "reactome": "R-SCE-5691001", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781053", "species_30555" ], "products": [ "species_10781051", "species_113541" ], "modifiers": [ [ "species_10781053", "catalyst" ] ], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W" ] }, "reaction_10779690": { "compartment": "compartment_7660", "id": "reaction_10779690", "reactome": "R-SCE-5689861", "name": "Recruitment of XPA and release of CAK ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779684", "species_10779650" ], "products": [ "species_10763257", "species_10779688" ], "modifiers": [], "additional_components": [ "Q08273", "YOL133W", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "P05759", "RPS31", "Q02939", "YPL122C", "P32628", "YEL037C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q06665", "YDR314C", "P06839", "RAD3", "YMR201C", "Q03290", "YDR460W", "P37366", "YPR025C", "P06242", "YDL108W", "Q08273", "YOL133W", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P28519", "YMR201C", "P32776", "YDR311W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q12004", "YPR056W", "P05759", "RPS31", "Q02939", "YPL122C", "P32628", "YEL037C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q06665", "YDR314C", "P06839", "RAD3" ] }, "reaction_10766961": { "compartment": "compartment_70101", "id": "reaction_10766961", "reactome": "R-SCE-196773", "name": "COASY phosphorylates DP-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196778" ], "products": [ "species_76194", "species_29370" ], "modifiers": [ [ "species_10766945", "catalyst" ] ], "additional_components": [ "YGR277C" ] }, "reaction_10766940": { "compartment": "compartment_70101", "id": "reaction_10766940", "reactome": "R-SCE-196753", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111707", "species_196786" ], "products": [ "species_196834", "species_111294", "species_76577" ], "modifiers": [ [ "species_10766937", "catalyst" ] ], "additional_components": [ "P40506", "YIL083C" ] }, "reaction_10766948": { "compartment": "compartment_70101", "id": "reaction_10766948", "reactome": "R-SCE-196754", "name": "COASY transfers an adenylyl group from ATP to PPANT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196767", "species_113592" ], "products": [ "species_196778", "species_111294" ], "modifiers": [ [ "species_10766945", "catalyst" ] ], "additional_components": [ "YGR277C" ] }, "reaction_10767291": { "compartment": "compartment_70616", "id": "reaction_10767291", "reactome": "R-SCE-199216", "name": "SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194" ], "products": [ "species_29374" ], "modifiers": [ [ "species_10767288", "catalyst" ] ], "additional_components": [ "YHR002W" ] }, "reaction_10766971": { "compartment": "compartment_70101", "id": "reaction_10766971", "reactome": "R-SCE-196840", "name": "3xPPCDC:3FMN decarboxylates PPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196834" ], "products": [ "species_196767", "species_113528" ], "modifiers": [ [ "species_10766968", "catalyst" ] ], "additional_components": [ "P36076", "YKL088W", "species_73524" ] }, "reaction_10779496": { "compartment": "compartment_7660", "id": "reaction_10779496", "reactome": "R-SCE-5686430", "name": "MUS81 binds EME1, EME2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779488", "species_10779481" ], "products": [ "species_10779494" ], "modifiers": [], "additional_components": [ "YDR386W", "YBR098W", "P38257", "YBR098W", "Q04149", "YDR386W" ] }, "reaction_10761487": { "compartment": "compartment_70101", "id": "reaction_10761487", "reactome": "R-SCE-70581", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76213", "species_29404" ], "products": [ "species_29448", "species_29406" ], "modifiers": [ [ "species_10761484", "catalyst" ] ], "additional_components": [ "P23542", "YLR027C" ] }, "reaction_10761500": { "compartment": "compartment_5460", "id": "reaction_10761500", "reactome": "R-SCE-70596", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113553" ], "products": [ "species_113552", "species_113587" ], "modifiers": [ [ "species_10761497", "catalyst" ] ], "additional_components": [ "Q01802", "YKL106W" ] }, "reaction_10761517": { "compartment": "compartment_70101", "id": "reaction_10761517", "reactome": "R-SCE-70599", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29448", "species_113592", "species_29356" ], "products": [ "species_29404", "species_29642", "species_111294", "species_76577" ], "modifiers": [ [ "species_10761514", "catalyst" ] ], "additional_components": [ "P49090", "YGR124W", "P49089", "YPR145W" ] }, "reaction_10781277": { "compartment": "compartment_876", "id": "reaction_10781277", "reactome": "R-SCE-5693783", "name": "NAALADases hydrolyse NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693762" ], "products": [ "species_29404", "species_5693772" ], "modifiers": [ [ "species_10781274", "catalyst" ] ], "additional_components": [ "Q08693", "YOR256C", "P47161", "YJR126C", "Q08919", "YPL176C" ] }, "reaction_10768525": { "compartment": "compartment_70101", "id": "reaction_10768525", "reactome": "R-SCE-372448", "name": "SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113553" ], "products": [ "species_29448", "species_113552" ], "modifiers": [ [ "species_10768520", "catalyst" ] ], "additional_components": [ "YPR021C" ] }, "reaction_10761489": { "compartment": "compartment_70101", "id": "reaction_10761489", "reactome": "R-SCE-70592", "name": "PXLP-K259-GOT1 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29448", "species_29406" ], "products": [ "species_29404", "species_76213" ], "modifiers": [ [ "species_10761484", "catalyst" ] ], "additional_components": [ "P23542", "YLR027C" ] }, "reaction_10782374": { "compartment": "compartment_7660", "id": "reaction_10782374", "reactome": "R-SCE-6791222", "name": "21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782324" ], "products": [ "species_10782340" ], "modifiers": [ [ "species_10782371", "catalyst" ], [ "species_10782359", "catalyst" ], [ "species_10782077", "catalyst" ], [ "species_10782345", "catalyst" ] ], "additional_components": [ "Q04177", "UTP5", "P53941", "IMP4", "Q02354", "UTP6", "P25368", "RRP7", "Q04217", "ECM16", "P06367", "RPS14A", "P25443", "RPS2", "P40498", "UTP25", "Q05498", "FCF1", "P35194", "UTP20", "Q99207", "NOP14", "P40362", "UTP18", "P34247", "UTP11", "Q04305", "UTP15", "Q06512", "NOC4", "P40055", "UTP7", "Q12220", "DIP2", "P33750", "SOF1", "Q08965", "BMS1", "P39990", "SNU13", "P47083", "MPP10", "Q06287", "EMG1", "P38719", "DBP8", "Q05022", "RRP5", "P45818", "ROK1", "P38712", "RRP3", "P05755", "RPS9B", "Q02931", "NAN1", "P42945", "UTP10", "Q08096", "RCL1", "Q12136", "SAS10", "Q06506", "RRP9", "P0CX37", "RPS6A", "Q06679", "UTP4", "P26786", "RPS7A", "P25586", "KRR1", "P15646", "NOP1", "Q05946", "UTP13", "Q12460", "NOP56", "Q06078", "UTP21", "P25635", "PWP2", "P53254", "UTP22", "Q04500", "UTP14", "P32899", "IMP3", "Q12481", "RRP36", "Q12499", "NOP58", "P0CX38", "RPS6B", "P39516", "RPS14B", "Q04177", "UTP5", "P53941", "IMP4", "Q02354", "UTP6", "P25368", "RRP7", "Q04217", "ECM16", "P06367", "RPS14A", "P25443", "RPS2", "P40498", "UTP25", "Q05498", "FCF1", "P35194", "UTP20", "Q99207", "NOP14", "P40362", "UTP18", "P34247", "UTP11", "Q04305", "UTP15", "Q06512", "NOC4", "P40055", "UTP7", "Q12220", "DIP2", "P33750", "SOF1", "Q08965", "BMS1", "P39990", "SNU13", "P47083", "MPP10", "Q06287", "EMG1", "P38719", "DBP8", "Q05022", "RRP5", "P45818", "ROK1", "P38712", "RRP3", "P05755", "RPS9B", "Q02931", "NAN1", "P42945", "UTP10", "Q08096", "RCL1", "Q12136", "SAS10", "Q06506", "RRP9", "P0CX37", "RPS6A", "Q06679", "UTP4", "P26786", "RPS7A", "P25586", "KRR1", "P15646", "NOP1", "Q05946", "UTP13", "Q12460", "NOP56", "Q06078", "UTP21", "P25635", "PWP2", "P53254", "UTP22", "Q04500", "UTP14", "P32899", "IMP3", "Q12481", "RRP36", "Q12499", "NOP58", "P0CX38", "RPS6B", "P39516", "RPS14B", "P38801", "YHR081W", "Q12149", "YOR001W", "P53859", "CSL4", "Q08285", "RRP40", "P53256", "RRP46", "Q12277", "RRP42", "P48240", "MTR3", "P38792", "RRP4", "P46948", "SKI6", "P47047", "YJL050W", "Q05636", "RRP45", "P25359", "RRP43", "YJL050W", "YOR001W" ] }, "reaction_10782565": { "compartment": "compartment_70101", "id": "reaction_10782565", "reactome": "R-SCE-6791223", "name": "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782539", "species_10782537" ], "products": [ "species_10782549", "species_10782541", "species_10762573", "species_10782555", "species_10782551", "species_10782539", "species_10782553", "species_10782557", "species_10782547", "species_10782545", "species_10782543" ], "modifiers": [ [ "species_10782545", "catalyst" ], [ "species_10782555", "catalyst" ], [ "species_10782563", "catalyst" ], [ "species_10782557", "catalyst" ] ], "additional_components": [ "YOR119C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "Q12196", "YOR119C", "P0CH08", "RPL40A", "P38333", "YBR247C", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "P34078", "YKL143W", "P0CX37", "RPS6A", "P38711", "RPS27B", "P38786", "YHR062C", "P0CX30", "RPS23B", "P40571", "YIR015W", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P50109", "YML017W", "P07280", "RPS19A", "P0CX39", "RPS8A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P0CX32", "RPS24B", "P40160", "YNL207W", "Q99216", "YOR145C", "P0CX35", "RPS4A", "P23248", "RPS1B", "P0CX47", "RPS11A", "P0CX56", "RPS18B", "P26786", "RPS7A", "Q01855", "RPS15", "P29295", "YPL204W", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "Q08444", "YOR056C", "P0CX40", "RPS8B", "P14127", "RPS17B", "Q07381", "YDL060W", "YNL207W", "YBR247C", "P0CX52", "RPS16B", "P35997", "RPS27A", "Q08745", "RPS10A", "P46784", "RPS10B", "P25443", "RPS2", "P06367", "RPS14A", "P0CX55", "RPS18A", "P0CX32", "RPS24B", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX35", "RPS4A", "P23248", "RPS1B", "P0CH08", "RPL40A", "P0CX47", "RPS11A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "P0CX37", "RPS6A", "P0CX56", "RPS18B", "P38711", "RPS27B", "P26786", "RPS7A", "P0CX30", "RPS23B", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P07281", "RPS19B", "P05759", "RPS31", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "YPL204W", "YDL060W", "YOR119C", "YOR119C", "YPL204W", "YOR145C", "YOR056C", "YKL143W", "YOR056C", "YPL204W", "YCR047C", "YPL204W" ] }, "reaction_10782116": { "compartment": "compartment_7660", "id": "reaction_10782116", "reactome": "R-SCE-6791219", "name": "32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782100" ], "products": [ "species_10782067" ], "modifiers": [ [ "species_10782063", "catalyst" ], [ "species_10782098", "catalyst" ], [ "species_10782114", "catalyst" ], [ "species_10782058", "catalyst" ] ], "additional_components": [ "Q12024", "YOR272W", "P38883", "YHR197W", "Q07845", "YLL035W", "P38803", "YHR085W", "P36146", "YKR063C", "Q02724", "YPL020C", "P53877", "YNL182C", "P53261", "YGR103W", "Q04660", "YMR049C", "P38883", "YHR197W", "Q07845", "YLL035W", "P38803", "YHR085W", "P36146", "YKR063C", "Q02724", "YPL020C", "P53877", "YNL182C", "YLL035W", "Q12024", "YOR272W", "P53261", "YGR103W", "Q04660", "YMR049C", "P36049", "YKL172W", "P40010", "YER006W", "P53261", "YGR103W", "YKR063C" ] }, "reaction_10767666": { "compartment": "compartment_70101", "id": "reaction_10767666", "reactome": "R-SCE-202164", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767662", "species_202277" ], "products": [ "species_10767664" ], "modifiers": [], "additional_components": [ "YOL100W", "species_202247", "species_179838", "species_202247", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10767681": { "compartment": "compartment_876", "id": "reaction_10767681", "reactome": "R-SCE-202222", "name": "Phosphorylation of PKC theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767671", "species_113592" ], "products": [ "species_29370", "species_10767678" ], "modifiers": [ [ "species_10767664", "catalyst" ] ], "additional_components": [ "species_112275", "P24583", "YBL105C", "species_112275", "P24583", "YBL105C", "species_202247", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10767319": { "compartment": "compartment_70101", "id": "reaction_10767319", "reactome": "R-SCE-199456", "name": "PTEN dephosphorylates PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_29356" ], "products": [ "species_29372", "species_179856" ], "modifiers": [ [ "species_10767316", "catalyst" ] ], "additional_components": [ "YNL128W" ] }, "reaction_10767687": { "compartment": "compartment_70101", "id": "reaction_10767687", "reactome": "R-SCE-202328", "name": "Translocation of PKC theta to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767566", "species_112275" ], "products": [ "species_10767685" ], "modifiers": [], "additional_components": [ "YBL105C", "species_112275", "P24583", "YBL105C" ] }, "reaction_10764508": { "compartment": "compartment_7660", "id": "reaction_10764508", "reactome": "R-SCE-109639", "name": "Formation of the closed pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763293", "species_10763806" ], "products": [ "species_10764070" ], "modifiers": [], "additional_components": [ "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "P32774", "YKL058W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10764504": { "compartment": "compartment_7660", "id": "reaction_10764504", "reactome": "R-SCE-109637", "name": "Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763800", "species_10763417", "species_10763422" ], "products": [ "species_10763802" ], "modifiers": [], "additional_components": [ "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "P32774", "YKL058W", "P32773", "YOR194C", "YPR086W", "Q04226", "YML015C", "Q12030", "YDR167W", "P23255", "YCR042C", "Q05021", "YMR227C", "P53040", "YGL112C", "P32774", "YKL058W", "P29055", "YPR086W", "Q03761", "YDR145W", "P13393", "SPT15", "Q05027", "YMR236W", "P38129", "YBR198C", "P50105", "YMR005W", "P46677", "YGR274C", "P11747", "YML098W", "P32773", "YOR194C" ] }, "reaction_10763808": { "compartment": "compartment_7660", "id": "reaction_10763808", "reactome": "R-SCE-75095", "name": "Binding of TFIIE to the growing preinitiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763503", "species_10763804" ], "products": [ "species_10763806" ], "modifiers": [], "additional_components": [ "P36100", "YKL028W", "P36145", "YKR062W", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "P32774", "YKL058W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P11747", "YML098W", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "P32774", "YKL058W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W" ] }, "reaction_10764502": { "compartment": "compartment_7660", "id": "reaction_10764502", "reactome": "R-SCE-109636", "name": "Recognition and Binding of Core Promoter Elements by TFIID", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109627", "species_10763491" ], "products": [ "species_10763800" ], "modifiers": [], "additional_components": [ "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15" ] }, "reaction_10764506": { "compartment": "compartment_7660", "id": "reaction_10764506", "reactome": "R-SCE-109638", "name": "Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762312", "species_10763802" ], "products": [ "species_10763804" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "Q04226", "YML015C", "Q12030", "YDR167W", "P23255", "YCR042C", "Q05021", "YMR227C", "P53040", "YGL112C", "P32774", "YKL058W", "P29055", "YPR086W", "Q03761", "YDR145W", "P13393", "SPT15", "Q05027", "YMR236W", "P38129", "YBR198C", "P50105", "YMR005W", "P46677", "YGR274C", "P11747", "YML098W", "P32773", "YOR194C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "P32774", "YKL058W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P11747", "YML098W" ] }, "reaction_10769195": { "compartment": "compartment_876", "id": "reaction_10769195", "reactome": "R-SCE-399998", "name": "Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10769192", "catalyst" ] ], "additional_components": [ "P32383", "YPL268W", "species_29438", "P10823", "YER020W" ] }, "reaction_10772682": { "compartment": "compartment_70101", "id": "reaction_10772682", "reactome": "R-SCE-1237160", "name": "MTA is cleaved and phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353106", "species_29372" ], "products": [ "species_83951", "species_1237165" ], "modifiers": [ [ "species_10772679", "catalyst" ] ], "additional_components": [ "Q07938", "YLR017W" ] }, "reaction_10772662": { "compartment": "compartment_70101", "id": "reaction_10772662", "reactome": "R-SCE-1237119", "name": "Acireductone is oxidized to MOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237155", "species_29368" ], "products": [ "species_1237122", "species_29460" ], "modifiers": [ [ "species_10772659", "catalyst" ] ], "additional_components": [ "species_111793", "Q03677", "YMR009W" ] }, "reaction_10772652": { "compartment": "compartment_70101", "id": "reaction_10772652", "reactome": "R-SCE-1237096", "name": "Methylthio-ribose-P = Methylthio-ribulose-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237165" ], "products": [ "species_1237107" ], "modifiers": [ [ "species_10772649", "catalyst" ] ], "additional_components": [ "YPR118W" ] }, "reaction_10772672": { "compartment": "compartment_70101", "id": "reaction_10772672", "reactome": "R-SCE-1237129", "name": "Acireductone is created", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237176", "species_29356" ], "products": [ "species_70106", "species_1237155", "species_29372" ], "modifiers": [ [ "species_10772669", "catalyst" ] ], "additional_components": [ "P32626", "YEL038W", "species_109496" ] }, "reaction_10787565": { "compartment": "compartment_70101", "id": "reaction_10787565", "reactome": "R-SCE-8951727", "name": "cAMP binds PKA tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764953", "species_30389" ], "products": [ "species_10764955" ], "modifiers": [], "additional_components": [ "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "species_30389" ] }, "reaction_10788654": { "compartment": "compartment_70101", "id": "reaction_10788654", "reactome": "R-SCE-9619355", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10788647" ], "products": [ "species_29370", "species_10788651" ], "modifiers": [ [ "species_10788647", "catalyst" ] ], "additional_components": [ "P06787", "YBR109C", "P43637", "YGL179C", "species_74016", "P06787", "YBR109C", "P43637", "YGL179C", "species_74016", "P06787", "YBR109C", "P43637", "YGL179C", "species_74016" ] }, "reaction_10788663": { "compartment": "compartment_70101", "id": "reaction_10788663", "reactome": "R-SCE-9619376", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767628", "species_10788659" ], "products": [ "species_10788661" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_74016", "YLR248W", "P06787", "YBR109C", "P38623", "YLR248W", "species_74016" ] }, "reaction_10764959": { "compartment": "compartment_70101", "id": "reaction_10764959", "reactome": "R-SCE-111925", "name": "cAMP induces dissociation of inactive PKA tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764955" ], "products": [ "species_10764957", "species_10764951" ], "modifiers": [], "additional_components": [ "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "species_30389", "P07278", "YIL033C", "species_30389", "P05986", "YKL166C", "P06245", "YPL203W", "P06244", "YJL164C" ] }, "reaction_10789248": { "compartment": "compartment_12045", "id": "reaction_10789248", "reactome": "R-SCE-9714361", "name": "RHOC activates endoplasmic reticulum effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789244", "species_10789214" ], "products": [ "species_10789246" ], "modifiers": [], "additional_components": [ "Q01590", "YLR026C", "Q12396", "YLR080W", "P43555", "YFL048C", "P36137", "YKR044W", "P40075", "YER120W", "P32462", "YNL280C", "Q6Q595", "YBL091C-A", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q01590", "YLR026C", "Q12396", "YLR080W", "Q00246", "YKR055W", "P06781", "YNL090W", "P43555", "YFL048C", "P36137", "YKR044W", "P06780", "YPR165W", "P40075", "YER120W", "species_29438", "P32462", "YNL280C", "Q6Q595", "YBL091C-A" ] }, "reaction_10788156": { "compartment": "compartment_876", "id": "reaction_10788156", "reactome": "R-SCE-9013437", "name": "RHOD GAPs stimulate RHOD GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136", "species_29356" ], "products": [ "species_29372", "species_10788124" ], "modifiers": [ [ "species_10788153", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "P39960", "YER155C", "Q06407", "YDR379W", "P38339", "YBR260C", "P32873", "YPL115C", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10789129": { "compartment": "compartment_17906", "id": "reaction_10789129", "reactome": "R-SCE-9693214", "name": "RHOD binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788063", "species_10789123" ], "products": [ "species_10789127" ], "modifiers": [], "additional_components": [ "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "P48562", "YNL298W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "Q03497", "YHL007C", "P06780", "YPR165W", "species_29438", "Q12469", "YOL113W" ] }, "reaction_10788047": { "compartment": "compartment_70101", "id": "reaction_10788047", "reactome": "R-SCE-9013108", "name": "GDIs block activation of RHOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787983", "species_10788033" ], "products": [ "species_10788045" ], "modifiers": [], "additional_components": [ "YDL135C", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29420", "Q12434", "YDL135C", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W" ] }, "reaction_10789250": { "compartment": "compartment_876", "id": "reaction_10789250", "reactome": "R-SCE-9714363", "name": "RHOC translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778611" ], "products": [ "species_10789214" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10788248": { "compartment": "compartment_876", "id": "reaction_10788248", "reactome": "R-SCE-9018768", "name": "RHOU auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10788245" ], "products": [ "species_10788230", "species_29420" ], "modifiers": [ [ "species_10788245", "catalyst" ] ], "additional_components": [ "species_29420", "P19073", "YLR229C", "species_29438", "P19073", "YLR229C", "species_29420", "P19073", "YLR229C" ] }, "reaction_10788109": { "compartment": "compartment_876", "id": "reaction_10788109", "reactome": "R-SCE-9013161", "name": "CDC42 GAPs stimulate CDC42 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10768894" ], "products": [ "species_10788091", "species_29372" ], "modifiers": [ [ "species_10788106", "catalyst" ] ], "additional_components": [ "species_29438", "P19073", "YLR229C", "species_29420", "P19073", "YLR229C", "P39960", "YER155C", "Q12128", "YOR134W", "Q06407", "YDR379W", "P38339", "YBR260C", "P32873", "YPL115C", "P17121", "YDR389W", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10789177": { "compartment": "compartment_70101", "id": "reaction_10789177", "reactome": "R-SCE-9696267", "name": "RND3 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10789173" ], "products": [ "species_10789175" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10788020": { "compartment": "compartment_70101", "id": "reaction_10788020", "reactome": "R-SCE-9013021", "name": "GDIs block activation of RHOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788014", "species_10788012" ], "products": [ "species_10788018" ], "modifiers": [], "additional_components": [ "YDL135C", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29420", "Q00245", "YIL118W", "Q12434", "YDL135C", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W" ] }, "reaction_10788031": { "compartment": "compartment_70101", "id": "reaction_10788031", "reactome": "R-SCE-9013024", "name": "RHOB binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788027", "species_10788022" ], "products": [ "species_10788029" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "Q08693", "YOR256C", "Q12280", "YPL242C", "P24583", "YBL105C", "P33328", "YOR327C", "P47161", "YJR126C", "Q04359", "YMR017W", "Q08919", "YPL176C", "P32525", "YJL201W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "P40357", "YGR009C", "Q08693", "YOR256C", "Q00246", "YKR055W", "P06781", "YNL090W", "P33328", "YOR327C", "P47161", "YJR126C", "Q04359", "YMR017W", "species_29438", "Q08919", "YPL176C", "P32525", "YJL201W", "Q00245", "YIL118W", "Q12280", "YPL242C", "P24583", "YBL105C", "P06780", "YPR165W" ] }, "reaction_10788295": { "compartment": "compartment_876", "id": "reaction_10788295", "reactome": "R-SCE-9018806", "name": "RAC3 GAPs stimulate RAC3 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788278", "species_29356" ], "products": [ "species_10788276", "species_29372" ], "modifiers": [ [ "species_10788292", "catalyst" ] ], "additional_components": [ "P53879", "YNL180C", "species_29438", "species_29420", "P53879", "YNL180C", "P39960", "YER155C", "Q06407", "YDR379W", "P38339", "YBR260C", "Q08227", "YOL065C", "P32873", "YPL115C", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10788305": { "compartment": "compartment_876", "id": "reaction_10788305", "reactome": "R-SCE-9018807", "name": "RAC3 GDIs block activation of RAC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788276", "species_10788297" ], "products": [ "species_10788303" ], "modifiers": [], "additional_components": [ "species_29420", "P53879", "YNL180C", "Q12434", "YDL135C", "species_29420", "P53879", "YNL180C", "Q12434", "YDL135C" ] }, "reaction_10789282": { "compartment": "compartment_876", "id": "reaction_10789282", "reactome": "R-SCE-9726862", "name": "Phosphorylated RHOU translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789276" ], "products": [ "species_10789280" ], "modifiers": [], "additional_components": [ "species_29420", "P19073", "YLR229C", "species_29420", "P19073", "YLR229C" ] }, "reaction_10788265": { "compartment": "compartment_876", "id": "reaction_10788265", "reactome": "R-SCE-9018794", "name": "RHOV binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788252", "species_10788261" ], "products": [ "species_10788263" ], "modifiers": [], "additional_components": [ "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "P39960", "YER155C", "Q03497", "YHL007C", "Q12280", "YPL242C", "Q06407", "YDR379W", "Q08924", "YPL183C", "P38339", "YBR260C", "P22137", "YGL206C", "P32873", "YPL115C", "Q12469", "YOL113W", "P17536", "YNL079C", "P19073", "YLR229C", "P39083", "YOR127W", "P48562", "YNL298W", "P39960", "YER155C", "P38339", "YBR260C", "species_29438", "P19073", "YLR229C", "Q03497", "YHL007C", "Q12280", "YPL242C", "Q06407", "YDR379W", "Q08924", "YPL183C", "P22137", "YGL206C", "P32873", "YPL115C", "Q12469", "YOL113W", "P17536", "YNL079C", "P39083", "YOR127W" ] }, "reaction_10788184": { "compartment": "compartment_876", "id": "reaction_10788184", "reactome": "R-SCE-9013438", "name": "RHOD binds effectors at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788168", "species_10788180" ], "products": [ "species_10788182" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "P40578", "YIR033W", "P35210", "YKL020C", "P32462", "YNL280C", "Q12091", "YPL170W", "P40578", "YIR033W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P35210", "YKL020C", "P06780", "YPR165W", "P32462", "YNL280C", "species_29438", "Q12091", "YPL170W" ] }, "reaction_10787825": { "compartment": "compartment_70101", "id": "reaction_10787825", "reactome": "R-SCE-8981637", "name": "RHOA GAPs stimulate RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10765231" ], "products": [ "species_10765229", "species_29372" ], "modifiers": [ [ "species_10787822", "catalyst" ] ], "additional_components": [ "P06780", "YPR165W", "species_29438", "species_29420", "P06780", "YPR165W", "P39960", "YER155C", "Q12128", "YOR134W", "Q06407", "YDR379W", "P38339", "YBR260C", "P32873", "YPL115C", "P17121", "YDR389W", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10788139": { "compartment": "compartment_876", "id": "reaction_10788139", "reactome": "R-SCE-9013435", "name": "RHOD auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10788124" ], "products": [ "species_10788136", "species_29420" ], "modifiers": [ [ "species_10788124", "catalyst" ] ], "additional_components": [ "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W" ] }, "reaction_10789125": { "compartment": "compartment_876", "id": "reaction_10789125", "reactome": "R-SCE-9693207", "name": "RHOD translocates to the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136" ], "products": [ "species_10789123" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10789143": { "compartment": "compartment_876", "id": "reaction_10789143", "reactome": "R-SCE-9693243", "name": "RHOD translocates to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136" ], "products": [ "species_10789141" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10788102": { "compartment": "compartment_876", "id": "reaction_10788102", "reactome": "R-SCE-9013159", "name": "CDC42 GEFs activate CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10788091" ], "products": [ "species_29420", "species_10768894" ], "modifiers": [ [ "species_10788099", "catalyst" ] ], "additional_components": [ "species_29420", "P19073", "YLR229C", "species_29438", "P19073", "YLR229C", "P04821", "YLR310C", "Q05670", "YMR232W", "P34216", "YBL047C", "P07866", "YAL024C", "P25300", "YCR038C", "P10823", "YER020W" ] }, "reaction_10789145": { "compartment": "compartment_876", "id": "reaction_10789145", "reactome": "R-SCE-9693282", "name": "RHOF GAPs stimulate RHOF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789100", "species_29356" ], "products": [ "species_10789098", "species_29372" ], "modifiers": [ [ "species_10788153", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "P39960", "YER155C", "Q06407", "YDR379W", "P38339", "YBR260C", "P32873", "YPL115C", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10788269": { "compartment": "compartment_876", "id": "reaction_10788269", "reactome": "R-SCE-9018798", "name": "RHOV binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10788267" ], "products": [ "species_10788252", "species_29420" ], "modifiers": [], "additional_components": [ "species_29420", "P19073", "YLR229C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10787993": { "compartment": "compartment_876", "id": "reaction_10787993", "reactome": "R-SCE-9013006", "name": "RHOA:GTP translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765231" ], "products": [ "species_10787991" ], "modifiers": [], "additional_components": [ "P06780", "YPR165W", "species_29438", "P06780", "YPR165W", "species_29438" ] }, "reaction_10787743": { "compartment": "compartment_70101", "id": "reaction_10787743", "reactome": "R-SCE-8980691", "name": "RHOA GEFs activate RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10765229" ], "products": [ "species_10765231", "species_29420" ], "modifiers": [ [ "species_10787740", "catalyst" ] ], "additional_components": [ "species_29420", "P06780", "YPR165W", "P06780", "YPR165W", "species_29438", "P04821", "YLR310C", "Q06409", "YLR422W", "P07866", "YAL024C", "P25300", "YCR038C" ] }, "reaction_10789092": { "compartment": "compartment_876", "id": "reaction_10789092", "reactome": "R-SCE-9690494", "name": "RHOB translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788022" ], "products": [ "species_10778663" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10788010": { "compartment": "compartment_876", "id": "reaction_10788010", "reactome": "R-SCE-9013009", "name": "RHOA binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788006", "species_10765231" ], "products": [ "species_10788008" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "Q08693", "YOR256C", "P33328", "YOR327C", "P22213", "YDR189W", "P47161", "YJR126C", "Q12229", "YDL091C", "Q04359", "YMR017W", "Q08919", "YPL176C", "P32525", "YJL201W", "Q12280", "YPL242C", "P24583", "YBL105C", "P40513", "YIL070C", "P36126", "YKR031C", "Q04228", "YML013W", "P06780", "YPR165W", "species_29438", "P40357", "YGR009C", "Q08693", "YOR256C", "P33328", "YOR327C", "P22213", "YDR189W", "P47161", "YJR126C", "Q12229", "YDL091C", "Q04359", "YMR017W", "species_29438", "Q08919", "YPL176C", "P32525", "YJL201W", "Q12280", "YPL242C", "P24583", "YBL105C", "P06780", "YPR165W", "P40513", "YIL070C", "P36126", "YKR031C", "Q04228", "YML013W" ] }, "reaction_10788053": { "compartment": "compartment_876", "id": "reaction_10788053", "reactome": "R-SCE-9013110", "name": "RHOC binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778611", "species_10788049" ], "products": [ "species_10788051" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q08693", "YOR256C", "Q12280", "YPL242C", "P24583", "YBL105C", "P33328", "YOR327C", "P06780", "YPR165W", "P40513", "YIL070C", "P47161", "YJR126C", "Q08919", "YPL176C", "P32525", "YJL201W", "Q00245", "YIL118W", "Q08693", "YOR256C", "Q00246", "YKR055W", "P06781", "YNL090W", "Q12280", "YPL242C", "P24583", "YBL105C", "P33328", "YOR327C", "P06780", "YPR165W", "P40513", "YIL070C", "P47161", "YJR126C", "species_29438", "Q08919", "YPL176C", "P32525", "YJL201W" ] }, "reaction_10788186": { "compartment": "compartment_876", "id": "reaction_10788186", "reactome": "R-SCE-9013452", "name": "RHOD:GTP translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136" ], "products": [ "species_10788168" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10789194": { "compartment": "compartment_70101", "id": "reaction_10789194", "reactome": "R-SCE-9696271", "name": "RND1 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769249", "species_10789190" ], "products": [ "species_10789192" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q08693", "YOR256C", "P19158", "YOL081W", "Q08924", "YPL183C", "P01120", "YNL098C", "Q04458", "YMR110C", "P15705", "YOR027W", "P18963", "YBR140C", "P47161", "YJR126C", "Q08919", "YPL176C", "Q08693", "YOR256C", "Q00246", "YKR055W", "P06781", "YNL090W", "P01120", "YNL098C", "P15705", "YOR027W", "P18963", "YBR140C", "P47161", "YJR126C", "species_29438", "Q08919", "YPL176C", "Q00245", "YIL118W", "P19158", "YOL081W", "Q08924", "YPL183C", "P06780", "YPR165W", "Q04458", "YMR110C" ] }, "reaction_10788055": { "compartment": "compartment_876", "id": "reaction_10788055", "reactome": "R-SCE-9013111", "name": "RHOC GAPs stimulate RHOC GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778611", "species_29356" ], "products": [ "species_10788033", "species_29372" ], "modifiers": [ [ "species_10787796", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "YJL201W" ] }, "reaction_10789111": { "compartment": "compartment_70101", "id": "reaction_10789111", "reactome": "R-SCE-9693198", "name": "RHOD binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136", "species_10789107" ], "products": [ "species_10789109" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "P48562", "YNL298W", "Q03497", "YHL007C", "P13517", "YIL034C", "P33328", "YOR327C", "P15891", "YCR088W", "P32939", "YML001W", "Q12469", "YOL113W", "P32525", "YJL201W", "P48562", "YNL298W", "Q00245", "YIL118W", "Q03497", "YHL007C", "Q00246", "YKR055W", "P06781", "YNL090W", "P13517", "YIL034C", "P33328", "YOR327C", "P15891", "YCR088W", "P32939", "YML001W", "P06780", "YPR165W", "species_29438", "Q12469", "YOL113W", "P32525", "YJL201W" ] }, "reaction_10789196": { "compartment": "compartment_70101", "id": "reaction_10789196", "reactome": "R-SCE-9696274", "name": "RND1 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10769247" ], "products": [ "species_10769249" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10789103": { "compartment": "compartment_876", "id": "reaction_10789103", "reactome": "R-SCE-9693111", "name": "RHOF auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10789098" ], "products": [ "species_10789100", "species_29420" ], "modifiers": [ [ "species_10789098", "catalyst" ] ], "additional_components": [ "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W" ] }, "reaction_10787989": { "compartment": "compartment_70101", "id": "reaction_10787989", "reactome": "R-SCE-9012835", "name": "GDIs block activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787983", "species_10765229" ], "products": [ "species_10787987" ], "modifiers": [], "additional_components": [ "YDL135C", "species_29420", "P06780", "YPR165W", "species_29420", "Q12434", "YDL135C", "P06780", "YPR165W" ] }, "reaction_10789096": { "compartment": "compartment_876", "id": "reaction_10789096", "reactome": "R-SCE-9692800", "name": "CDC42 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768894" ], "products": [ "species_10789094" ], "modifiers": [], "additional_components": [ "species_29438", "P19073", "YLR229C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10788243": { "compartment": "compartment_876", "id": "reaction_10788243", "reactome": "R-SCE-9018766", "name": "RHOU binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788230", "species_10788239" ], "products": [ "species_10788241" ], "modifiers": [], "additional_components": [ "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "P53281", "YGR136W", "P39940", "YER125W", "Q03497", "YHL007C", "Q12280", "YPL242C", "P38753", "YHL002W", "Q08924", "YPL183C", "P34216", "YBL047C", "P39013", "YNL084C", "P22137", "YGL206C", "P32521", "YIR006C", "Q12469", "YOL113W", "P19073", "YLR229C", "P48562", "YNL298W", "P53281", "YGR136W", "P39940", "YER125W", "P38753", "YHL002W", "P34216", "YBL047C", "species_29438", "P19073", "YLR229C", "Q03497", "YHL007C", "Q12280", "YPL242C", "Q08924", "YPL183C", "P39013", "YNL084C", "P22137", "YGL206C", "P32521", "YIR006C", "Q12469", "YOL113W" ] }, "reaction_10788095": { "compartment": "compartment_876", "id": "reaction_10788095", "reactome": "R-SCE-9013158", "name": "CDC42 GDIs block activation of CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787983", "species_10788091" ], "products": [ "species_10788093" ], "modifiers": [], "additional_components": [ "YDL135C", "species_29420", "P19073", "YLR229C", "species_29420", "Q12434", "YDL135C", "P19073", "YLR229C" ] }, "reaction_10788025": { "compartment": "compartment_70101", "id": "reaction_10788025", "reactome": "R-SCE-9013022", "name": "RHOB GAPs stimulate RHOB GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10788022" ], "products": [ "species_10788012", "species_29372" ], "modifiers": [ [ "species_10787796", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "YJL201W" ] }, "reaction_10789198": { "compartment": "compartment_70101", "id": "reaction_10789198", "reactome": "R-SCE-9696275", "name": "RND2 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10789161" ], "products": [ "species_10789163" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10789256": { "compartment": "compartment_876", "id": "reaction_10789256", "reactome": "R-SCE-9714694", "name": "RAC3 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788278" ], "products": [ "species_10789254" ], "modifiers": [], "additional_components": [ "P53879", "YNL180C", "species_29438", "P53879", "YNL180C", "species_29438" ] }, "reaction_10764078": { "compartment": "compartment_7660", "id": "reaction_10764078", "reactome": "R-SCE-75866", "name": "Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764066" ], "products": [ "species_10764074" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q05027", "YMR236W", "species_6806881", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "P38129", "YBR198C", "Q02939", "YPL122C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32774", "YKL058W", "P32776", "YDR311W", "P13393", "SPT15", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10764086": { "compartment": "compartment_7660", "id": "reaction_10764086", "reactome": "R-SCE-75873", "name": "Addition of Nucleotides 5 through 9 on the growing Transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764080" ], "products": [ "species_10763503", "species_10763491", "species_113541", "species_10763417", "species_10764084" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P36100", "YKL028W", "P36145", "YKR062W", "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "P32774", "YKL058W", "P32773", "YOR194C", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764068": { "compartment": "compartment_7660", "id": "reaction_10764068", "reactome": "R-SCE-75861", "name": "NTP Binds Active Site of RNA Polymerase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764062" ], "products": [ "species_10764066" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q05027", "YMR236W", "species_6806881", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "P38129", "YBR198C", "Q02939", "YPL122C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32774", "YKL058W", "P32776", "YDR311W", "P13393", "SPT15", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10764035": { "compartment": "compartment_7660", "id": "reaction_10764035", "reactome": "R-SCE-75850", "name": "Addition of the third nucleotide on the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10763505" ], "products": [ "species_10764032", "species_113541" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764285": { "compartment": "compartment_7660", "id": "reaction_10764285", "reactome": "R-SCE-76576", "name": "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764084" ], "products": [ "species_10764283", "species_113541" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764082": { "compartment": "compartment_7660", "id": "reaction_10764082", "reactome": "R-SCE-75869", "name": "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764032" ], "products": [ "species_10764080", "species_113541", "species_10763422" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "YPR086W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10788639": { "compartment": "compartment_7660", "id": "reaction_10788639", "reactome": "R-SCE-9613497", "name": "Unwinding DNA for the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10763505" ], "products": [ "species_10763505", "species_113541" ], "modifiers": [ [ "species_10763293", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W" ] }, "reaction_10788637": { "compartment": "compartment_7660", "id": "reaction_10788637", "reactome": "R-SCE-9613494", "name": "Unwinding of DNA for the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10764032" ], "products": [ "species_10764032", "species_164121", "species_113541" ], "modifiers": [ [ "species_10763293", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W" ] }, "reaction_10764076": { "compartment": "compartment_7660", "id": "reaction_10764076", "reactome": "R-SCE-75864", "name": "Newly Formed Phosphodiester Bond Stabilized and PPi Released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764074" ], "products": [ "species_10763505", "species_113541" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10764162": { "compartment": "compartment_7660", "id": "reaction_10764162", "reactome": "R-SCE-75949", "name": "RNA Polymerase II Promoter Opening: First Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10764070" ], "products": [ "species_113582", "species_113550", "species_10764062" ], "modifiers": [ [ "species_10763293", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W" ] }, "reaction_10764829": { "compartment": "compartment_7660", "id": "reaction_10764829", "reactome": "R-SCE-111264", "name": "Addition of nucleotides between position +11 and +30", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764283" ], "products": [ "species_10764338", "species_113541" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10780889": { "compartment": "compartment_70101", "id": "reaction_10780889", "reactome": "R-SCE-5690152", "name": "USP5 cleaves polyubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10780884", "species_29356" ], "products": [ "species_10760634", "species_10780886" ], "modifiers": [ [ "species_10780884", "catalyst" ] ], "additional_components": [ "P38237", "YBR058C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38237", "YBR058C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38237", "YBR058C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10781695": { "compartment": "compartment_7660", "id": "reaction_10781695", "reactome": "R-SCE-5697009", "name": "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781688", "species_113518" ], "products": [ "species_10780391", "species_10781692" ], "modifiers": [ [ "species_10781688", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "Q01939", "YGL048C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03940", "YDR190C", "P38187", "YBL067C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P13365", "YAL040C", "P20438", "YPL256C", "Q01939", "YGL048C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03940", "YDR190C", "P38187", "YBL067C", "P13365", "YAL040C", "P20438", "YPL256C", "Q01939", "YGL048C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03940", "YDR190C", "P38187", "YBL067C" ] }, "reaction_10780495": { "compartment": "compartment_7660", "id": "reaction_10780495", "reactome": "R-SCE-5690080", "name": "USP3,SAGA deubiquitinate Histone H2A,H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10780488", "species_113518" ], "products": [ "species_10780492", "species_10760537" ], "modifiers": [ [ "species_10780488", "catalyst" ] ], "additional_components": [ "Q05027", "YMR236W", "P50102", "YMR223W", "P02294", "YBL002W", "Q12030", "YDR167W", "P28003", "YAL034C", "P32494", "YDR176W", "Q99326", "YOR338W", "Q02336", "YDR448W", "Q03330", "YGR252W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "Q05027", "YMR236W", "P50102", "YMR223W", "P02294", "YBL002W", "Q12030", "YDR167W", "P28003", "YAL034C", "P32494", "YDR176W", "Q99326", "YOR338W", "Q02336", "YDR448W", "Q03330", "YGR252W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05027", "YMR236W", "P50102", "YMR223W", "P02294", "YBL002W", "Q12030", "YDR167W", "P28003", "YAL034C", "P32494", "YDR176W", "Q99326", "YOR338W", "Q02336", "YDR448W", "Q03330", "YGR252W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W" ] }, "reaction_10771848": { "compartment": "compartment_70101", "id": "reaction_10771848", "reactome": "R-SCE-936390", "name": "CYLD mediated deubiquitination of DDX58 (RIG-I)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771819" ], "products": [ "species_10760634", "species_10771837" ], "modifiers": [ [ "species_10771845", "catalyst" ] ], "additional_components": [ "P40434", "YML133C", "P40889", "YML133C", "Q7M4S9", "YML133C", "Q03099", "YML133C", "P53819", "YNL339C", "Q99208", "YML133C", "Q07888", "YML133C", "P38721", "YML133C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40434", "YML133C", "P40889", "YML133C", "Q7M4S9", "YML133C", "Q03099", "YML133C", "P53819", "YNL339C", "Q99208", "YML133C", "Q07888", "YML133C", "P38721", "YML133C", "P33442", "RPS1A", "P23248", "RPS1B" ] }, "reaction_10779645": { "compartment": "compartment_70101", "id": "reaction_10779645", "reactome": "R-SCE-5689539", "name": "ADRM1:26S proteaseome binds USP14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779636", "species_10779641" ], "products": [ "species_10779643" ], "modifiers": [], "additional_components": [ "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W", "YFR010W", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P43593", "YFR010W", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10781707": { "compartment": "compartment_70101", "id": "reaction_10781707", "reactome": "R-SCE-6781779", "name": "USP13 deubiquitinates BECN1,USP10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781702", "species_29356" ], "products": [ "species_10781704", "species_10766135" ], "modifiers": [ [ "species_10781702", "catalyst" ] ], "additional_components": [ "P38237", "YBR058C", "Q02948", "YPL120W", "P38237", "YBR058C", "Q02948", "YPL120W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38237", "YBR058C", "Q02948", "YPL120W" ] }, "reaction_10780394": { "compartment": "compartment_7660", "id": "reaction_10780394", "reactome": "R-SCE-5689950", "name": "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10779716" ], "products": [ "species_10780391", "species_10779722" ], "modifiers": [ [ "species_10779716", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "P50101", "YMR304W", "Q08747", "YOR295W", "P53916", "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P50101", "YMR304W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P53916", "YNL128W", "Q05024", "YMR233W", "P50101", "YMR304W", "Q08747", "YOR295W", "P53916", "YNL128W" ] }, "reaction_10761428": { "compartment": "compartment_70101", "id": "reaction_10761428", "reactome": "R-SCE-70523", "name": "PXLP-K314-GPT transaminates L-Ala to form PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29432" ], "products": [ "species_29404", "species_29398" ], "modifiers": [ [ "species_10761425", "catalyst" ] ], "additional_components": [ "P52893", "YLR089C" ] }, "reaction_10771076": { "compartment": "compartment_5460", "id": "reaction_10771076", "reactome": "R-SCE-507749", "name": "PXLP-K341-GPT2 transaminates PYR to form L-Ala", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113557" ], "products": [ "species_113594", "species_379697" ], "modifiers": [ [ "species_10771073", "catalyst" ] ], "additional_components": [ "P52893", "YLR089C", "P52892", "YDR111C" ] }, "reaction_10787978": { "compartment": "compartment_5460", "id": "reaction_10787978", "reactome": "R-SCE-9012721", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012724", "species_9012592" ], "products": [ "species_1614595", "species_113557" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C" ] }, "reaction_10788188": { "compartment": "compartment_5460", "id": "reaction_10788188", "reactome": "R-SCE-9013471", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013199", "species_9012592" ], "products": [ "species_113557", "species_9013191" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C" ] }, "reaction_10788112": { "compartment": "compartment_5460", "id": "reaction_10788112", "reactome": "R-SCE-9013198", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_9013199" ], "products": [ "species_9013207", "species_9013191" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C" ] }, "reaction_10788190": { "compartment": "compartment_5460", "id": "reaction_10788190", "reactome": "R-SCE-9013533", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013543", "species_9013199" ], "products": [ "species_113557", "species_9013191" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C" ] }, "reaction_10773393": { "compartment": "compartment_70101", "id": "reaction_10773393", "reactome": "R-SCE-1614567", "name": "Excess homocysteine yields homolanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369" ], "products": [ "species_1614532", "species_1614594" ], "modifiers": [ [ "species_10773390", "catalyst" ], [ "species_174369", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10773404": { "compartment": "compartment_70101", "id": "reaction_10773404", "reactome": "R-SCE-1614631", "name": "Homocysteine is degraded to oxobutanoate and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369", "species_29356" ], "products": [ "species_1614532", "species_29382", "species_936714" ], "modifiers": [ [ "species_10773390", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10773399": { "compartment": "compartment_70101", "id": "reaction_10773399", "reactome": "R-SCE-1614591", "name": "Excess cysteine yields lanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707" ], "products": [ "species_1614532", "species_1614582" ], "modifiers": [ [ "species_10773390", "catalyst" ], [ "species_111707", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10773401": { "compartment": "compartment_70101", "id": "reaction_10773401", "reactome": "R-SCE-1614614", "name": "Cysteine is degraded to serine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_29356" ], "products": [ "species_1614532", "species_200736" ], "modifiers": [ [ "species_10773390", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10788493": { "compartment": "compartment_5460", "id": "reaction_10788493", "reactome": "R-SCE-9034756", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787975", "species_9012592" ], "products": [ "species_113557", "species_10788491" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C", "YOR251C", "YOR251C" ] }, "reaction_10773382": { "compartment": "compartment_70616", "id": "reaction_10773382", "reactome": "R-SCE-1614546", "name": "Sulfate is exported to the cytosol in exchange for dicarboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614584", "species_198498" ], "products": [ "species_174375", "species_113544" ], "modifiers": [ [ "species_10768552", "catalyst" ] ], "additional_components": [ "YLR348C" ] }, "reaction_10778010": { "compartment": "compartment_70101", "id": "reaction_10778010", "reactome": "R-SCE-5623508", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10778008" ], "products": [ "species_10778006", "species_29420" ], "modifiers": [ [ "species_10768383", "catalyst" ] ], "additional_components": [ "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "P11076", "YDL192W", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C" ] }, "reaction_10773127": { "compartment": "compartment_12045", "id": "reaction_10773127", "reactome": "R-SCE-1482825", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[11]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10773124", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10773178": { "compartment": "compartment_12045", "id": "reaction_10773178", "reactome": "R-SCE-1482932", "name": "PI is hydrolyzed to 2-acyl LPI by PLA2[13]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498737", "species_1524021" ], "modifiers": [ [ "species_10773175", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10773030": { "compartment": "compartment_12045", "id": "reaction_10773030", "reactome": "R-SCE-1482626", "name": "2-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498737", "species_1500578" ], "products": [ "species_76194", "species_426639" ], "modifiers": [ [ "species_10772972", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10772975": { "compartment": "compartment_12045", "id": "reaction_10772975", "reactome": "R-SCE-1482598", "name": "1-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498733", "species_1500578" ], "products": [ "species_76194", "species_426639" ], "modifiers": [ [ "species_10772972", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10773155": { "compartment": "compartment_12045", "id": "reaction_10773155", "reactome": "R-SCE-1482868", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[12]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10764802": { "compartment": "compartment_7660", "id": "reaction_10764802", "reactome": "R-SCE-110316", "name": "POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764798", "species_10764794" ], "products": [ "species_10764800" ], "modifiers": [], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "YDR419W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10764811": { "compartment": "compartment_7660", "id": "reaction_10764811", "reactome": "R-SCE-110317", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764800", "species_29604" ], "products": [ "species_113541", "species_10764808" ], "modifiers": [ [ "species_10764800", "catalyst" ] ], "additional_components": [ "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10778443": { "compartment": "compartment_7660", "id": "reaction_10778443", "reactome": "R-SCE-5654985", "name": "SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778439", "species_10778423" ], "products": [ "species_10778441" ], "modifiers": [], "additional_components": [ "P33755", "YBR170C", "P53044", "YGR048W", "P25694", "YDL126C", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P33755", "YBR170C", "P38630", "YOR217W", "P40339", "YOL094C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P53044", "YGR048W", "P25694", "YDL126C" ] }, "reaction_10778448": { "compartment": "compartment_7660", "id": "reaction_10778448", "reactome": "R-SCE-5654989", "name": "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10778441" ], "products": [ "species_113582", "species_10778445", "species_10764794" ], "modifiers": [ [ "species_10778441", "catalyst" ] ], "additional_components": [ "Q04049", "YDR419W", "P33755", "YBR170C", "P38630", "YOR217W", "P40339", "YOL094C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P53044", "YGR048W", "P25694", "YDL126C", "P33755", "YBR170C", "P38630", "YOR217W", "P40339", "YOL094C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P53044", "YGR048W", "P25694", "YDL126C", "YDR419W", "Q04049", "YDR419W", "P33755", "YBR170C", "P38630", "YOR217W", "P40339", "YOL094C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P53044", "YGR048W", "P25694", "YDL126C" ] }, "reaction_10764818": { "compartment": "compartment_7660", "id": "reaction_10764818", "reactome": "R-SCE-110319", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10764808" ], "products": [ "species_113541", "species_10764815" ], "modifiers": [ [ "species_10764808", "catalyst" ] ], "additional_components": [ "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10785235": { "compartment": "compartment_12045", "id": "reaction_10785235", "reactome": "R-SCE-6814254", "name": "PNPLA6 hydrolyzes LysoPtdCho", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6814253", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10785232", "catalyst" ] ], "additional_components": [ "YML059C" ] }, "reaction_10785323": { "compartment": "compartment_876", "id": "reaction_10785323", "reactome": "R-SCE-6814797", "name": "ENPP6 hydrolyzes lysophosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2239407" ], "products": [ "species_6814794", "species_6814795" ], "modifiers": [ [ "species_10785320", "catalyst" ] ], "additional_components": [ "P39997", "YEL016C", "P25353", "YCR026C" ] }, "reaction_10773783": { "compartment": "compartment_70101", "id": "reaction_10773783", "reactome": "R-SCE-1855179", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629770" ], "modifiers": [ [ "species_10773780", "catalyst" ] ], "additional_components": [ "YDR315C" ] }, "reaction_10773735": { "compartment": "compartment_70101", "id": "reaction_10773735", "reactome": "R-SCE-1855165", "name": "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_1629765", "species_29372" ], "modifiers": [ [ "species_10773732", "catalyst" ] ], "additional_components": [ "CHEBI:62924", "species_2023931", "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773751": { "compartment": "compartment_7660", "id": "reaction_10773751", "reactome": "R-SCE-1855176", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023929" ], "modifiers": [ [ "species_10773748", "catalyst" ] ], "additional_components": [ "YDR315C" ] }, "reaction_10773839": { "compartment": "compartment_70101", "id": "reaction_10773839", "reactome": "R-SCE-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_994123", "species_29372" ], "modifiers": [ [ "species_10773740", "catalyst" ] ], "additional_components": [ "P50942", "YNL106C", "Q08227", "YOL065C" ] }, "reaction_10773738": { "compartment": "compartment_70101", "id": "reaction_10773738", "reactome": "R-SCE-1855166", "name": "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023943", "species_29356" ], "products": [ "species_29372", "species_994141" ], "modifiers": [ [ "species_10773726", "catalyst" ] ], "additional_components": [ "species_1629736", "species_2023922", "CHEBI:62927", "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773870": { "compartment": "compartment_70101", "id": "reaction_10773870", "reactome": "R-SCE-1855223", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629755" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773743": { "compartment": "compartment_70101", "id": "reaction_10773743", "reactome": "R-SCE-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114520", "species_29356" ], "products": [ "species_1629739", "species_29372" ], "modifiers": [ [ "species_10773740", "catalyst" ] ], "additional_components": [ "P50942", "YNL106C", "Q08227", "YOL065C" ] }, "reaction_10773702": { "compartment": "compartment_7660", "id": "reaction_10773702", "reactome": "R-SCE-1855157", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023932" ], "products": [ "species_113582", "species_2023931" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773778": { "compartment": "compartment_70101", "id": "reaction_10773778", "reactome": "R-SCE-1855178", "name": "Glc6P is isomerised to I3P by ISYNA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629756" ], "products": [ "species_1629731" ], "modifiers": [ [ "species_10773775", "catalyst" ] ], "additional_components": [ "species_113526", "P11986", "YJL153C" ] }, "reaction_10773810": { "compartment": "compartment_70101", "id": "reaction_10773810", "reactome": "R-SCE-1855205", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_114520", "species_29372" ], "modifiers": [ [ "species_10773807", "catalyst" ] ], "additional_components": [ "P53916", "YNL128W", "species_109496" ] }, "reaction_10773826": { "compartment": "compartment_876", "id": "reaction_10773826", "reactome": "R-SCE-1855213", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_994123", "species_29372" ], "modifiers": [ [ "species_10773821", "catalyst" ] ], "additional_components": [ "YOL065C" ] }, "reaction_10773715": { "compartment": "compartment_70101", "id": "reaction_10773715", "reactome": "R-SCE-1855158", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629759" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773968": { "compartment": "compartment_70101", "id": "reaction_10773968", "reactome": "R-SCE-2023971", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023974", "species_29356" ], "products": [ "species_1629770", "species_29372" ], "modifiers": [ [ "species_10773732", "catalyst" ] ], "additional_components": [ "CHEBI:62922", "species_2023932", "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773816": { "compartment": "compartment_70101", "id": "reaction_10773816", "reactome": "R-SCE-1855210", "name": "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629731" ], "products": [ "species_426910", "species_29372" ], "modifiers": [ [ "species_10773680", "catalyst" ] ], "additional_components": [ "P38710", "YHR046C", "Q05533", "YDR287W", "species_109496" ] }, "reaction_10773864": { "compartment": "compartment_876", "id": "reaction_10773864", "reactome": "R-SCE-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10773861", "catalyst" ] ], "additional_components": [ "species_74016", "P32383", "YPL268W" ] }, "reaction_10773813": { "compartment": "compartment_7660", "id": "reaction_10773813", "reactome": "R-SCE-1855207", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023929" ], "products": [ "species_113582", "species_2023940" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773867": { "compartment": "compartment_876", "id": "reaction_10773867", "reactome": "R-SCE-1855222", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114520", "species_29356" ], "products": [ "species_1629739", "species_29372" ], "modifiers": [ [ "species_10773821", "catalyst" ] ], "additional_components": [ "YOL065C" ] }, "reaction_10773786": { "compartment": "compartment_7660", "id": "reaction_10773786", "reactome": "R-SCE-1855181", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023922" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773876": { "compartment": "compartment_70101", "id": "reaction_10773876", "reactome": "R-SCE-1855227", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629770", "species_113592" ], "products": [ "species_29370", "species_1629765" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773768": { "compartment": "compartment_70101", "id": "reaction_10773768", "reactome": "R-SCE-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10773765", "catalyst" ] ], "additional_components": [ "P32383", "YPL268W", "species_74016" ] }, "reaction_10773799": { "compartment": "compartment_70101", "id": "reaction_10773799", "reactome": "R-SCE-1855193", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629736" ], "products": [ "species_29370", "species_1629738" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773836": { "compartment": "compartment_70101", "id": "reaction_10773836", "reactome": "R-SCE-1855216", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629770", "species_113592" ], "products": [ "species_29370", "species_1629740" ], "modifiers": [ [ "species_10773791", "catalyst" ] ], "additional_components": [ "YLR410W" ] }, "reaction_10773873": { "compartment": "compartment_7660", "id": "reaction_10773873", "reactome": "R-SCE-1855224", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023940", "species_29358" ], "products": [ "species_113582", "species_2023941" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773805": { "compartment": "compartment_70101", "id": "reaction_10773805", "reactome": "R-SCE-1855198", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_29356" ], "products": [ "species_1629770", "species_29372" ], "modifiers": [ [ "species_10773732", "catalyst" ] ], "additional_components": [ "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773819": { "compartment": "compartment_70101", "id": "reaction_10773819", "reactome": "R-SCE-1855211", "name": "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629753", "species_29356" ], "products": [ "species_426910", "species_29372" ], "modifiers": [ [ "species_10773680", "catalyst" ] ], "additional_components": [ "P38710", "YHR046C", "Q05533", "YDR287W", "species_109496" ] }, "reaction_10773796": { "compartment": "compartment_70101", "id": "reaction_10773796", "reactome": "R-SCE-1855182", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629732" ], "modifiers": [ [ "species_10773791", "catalyst" ] ], "additional_components": [ "YLR410W" ] }, "reaction_10773970": { "compartment": "compartment_70101", "id": "reaction_10773970", "reactome": "R-SCE-2023973", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_2023974", "species_29372" ], "modifiers": [ [ "species_10773732", "catalyst" ] ], "additional_components": [ "CHEBI:62924", "species_2023931", "CHEBI:62922", "species_2023932", "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773879": { "compartment": "compartment_7660", "id": "reaction_10773879", "reactome": "R-SCE-1855230", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023922", "species_29358" ], "products": [ "species_113582", "species_2023948" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773802": { "compartment": "compartment_70101", "id": "reaction_10773802", "reactome": "R-SCE-1855194", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629740" ], "products": [ "species_29370", "species_1629732" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773833": { "compartment": "compartment_12045", "id": "reaction_10773833", "reactome": "R-SCE-1855214", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023856", "species_29356" ], "products": [ "species_114520", "species_1500596" ], "modifiers": [ [ "species_10773830", "catalyst" ] ], "additional_components": [ "species_74016", "P32383", "YPL268W" ] }, "reaction_10773683": { "compartment": "compartment_70101", "id": "reaction_10773683", "reactome": "R-SCE-1855154", "name": "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_870330", "species_29356" ], "products": [ "species_426910", "species_29372" ], "modifiers": [ [ "species_10773680", "catalyst" ] ], "additional_components": [ "P38710", "YHR046C", "Q05533", "YDR287W", "species_109496" ] }, "reaction_10778372": { "compartment": "compartment_7660", "id": "reaction_10778372", "reactome": "R-SCE-5653780", "name": "USP43 binds ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778364", "species_10778368" ], "products": [ "species_10778370" ], "modifiers": [], "additional_components": [ "P39538", "YJL197W", "P32571", "YDR069C", "P39944", "YER144C", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P39538", "YJL197W", "P38251", "YBR087W", "P32571", "YDR069C", "P15873", "YBR088C", "P38629", "YNL290W", "P39944", "YER144C" ] }, "reaction_10778378": { "compartment": "compartment_7660", "id": "reaction_10778378", "reactome": "R-SCE-5653838", "name": "POLD,POLE binds deISGylated PCNA after TLS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778374", "species_10764822" ], "products": [ "species_10778376" ], "modifiers": [], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P40366", "YJL065C", "P27344", "YBR278W", "P26754", "YNL312W", "P40339", "YOL094C", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10765202": { "compartment": "compartment_7660", "id": "reaction_10765202", "reactome": "R-SCE-113504", "name": "Detection of damage during initiation of DNA synthesis in S-phase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760830" ], "products": [ "species_10760246", "species_113656" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W" ] }, "reaction_10767970": { "compartment": "compartment_12045", "id": "reaction_10767970", "reactome": "R-SCE-203979", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767870", "species_10767966" ], "products": [ "species_10767968" ], "modifiers": [], "additional_components": [ "P20606", "YPL218W", "species_29438", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "species_29438" ] }, "reaction_10772440": { "compartment": "compartment_17957", "id": "reaction_10772440", "reactome": "R-SCE-983158", "name": "Trimming of peptides in ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983034" ], "products": [ "species_983033", "species_8943716" ], "modifiers": [ [ "species_10772437", "catalyst" ] ], "additional_components": [ "P40462", "YIL137C", "P32454", "YKL157W", "P37898", "YHR047C" ] }, "reaction_10761054": { "compartment": "compartment_7660", "id": "reaction_10761054", "reactome": "R-SCE-69199", "name": "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10761046" ], "products": [ "species_113550", "species_10761041" ], "modifiers": [ [ "species_10761051", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "YMR036C" ] }, "reaction_10766479": { "compartment": "compartment_7660", "id": "reaction_10766479", "reactome": "R-SCE-188350", "name": "CAK-mediated phosphorylation of Cyclin E:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10761041" ], "products": [ "species_113582", "species_10760879" ], "modifiers": [ [ "species_10763257", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03290", "YDR460W", "P37366", "YPR025C", "P06242", "YDL108W" ] }, "reaction_10760390": { "compartment": "compartment_7660", "id": "reaction_10760390", "reactome": "R-SCE-68918", "name": "CDK and DDK associate with the Mcm10:pre-replicative complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760326", "species_10760314", "species_10760375" ], "products": [ "species_10760377" ], "modifiers": [], "additional_components": [ "P06243", "YDL017W", "P32325", "YDR052C", "P00546", "YBR160W", "P24279", "MCM3", "P29469", "MCM2", "P32833", "ORC2", "P38132", "MCM7", "P54791", "ORC4", "P54784", "phospho-ORC1", "P30665", "MCM4", "P32354", "YIL150C", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P54790", "ORC3", "P29496", "MCM5", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "P54791", "ORC4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10760383": { "compartment": "compartment_7660", "id": "reaction_10760383", "reactome": "R-SCE-68914", "name": "DNA polymerase alpha:primase binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760246", "species_10760277" ], "products": [ "species_10760279" ], "modifiers": [ [ "species_10760381", "catalyst" ] ], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P20457", "YKL045W", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P22336", "YAR007C", "P54791", "ORC4", "P26754", "YNL312W", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10761037": { "compartment": "compartment_70101", "id": "reaction_10761037", "reactome": "R-SCE-69191", "name": "Formation of Cyclin E:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760999", "species_10761033" ], "products": [ "species_10761035" ], "modifiers": [], "additional_components": [ "YBR160W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760840": { "compartment": "compartment_7660", "id": "reaction_10760840", "reactome": "R-SCE-68960", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760275", "species_68419" ], "products": [ "species_10760277" ], "modifiers": [ [ "species_10760381", "catalyst" ] ], "additional_components": [ "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P22336", "YAR007C", "P54791", "ORC4", "P26754", "YNL312W", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10760838": { "compartment": "compartment_7660", "id": "reaction_10760838", "reactome": "R-SCE-68954", "name": "Mcm2-7 is phosphorylated by DDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10760363" ], "products": [ "species_113582", "species_10760835" ], "modifiers": [ [ "species_10760326", "catalyst" ] ], "additional_components": [ "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "species_29372", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29496", "MCM5", "P06243", "YDL017W", "P32325", "YDR052C" ] }, "reaction_10765436": { "compartment": "compartment_13231", "id": "reaction_10765436", "reactome": "R-SCE-157906", "name": "Translocation of Cyclin E:Cdk2 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761035" ], "products": [ "species_10761041" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760400": { "compartment": "compartment_7660", "id": "reaction_10760400", "reactome": "R-SCE-68919", "name": "Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760396", "species_10760331" ], "products": [ "species_10760398" ], "modifiers": [], "additional_components": [ "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P32833", "ORC2", "P54791", "ORC4", "P30665", "MCM4", "P54784", "phospho-ORC1", "P09119", "CDC6", "P53091", "MCM6", "P50874", "ORC5", "P29496", "MCM5", "P54790", "ORC3", "YIL150C", "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P32833", "ORC2", "P54791", "ORC4", "P30665", "MCM4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P09119", "CDC6", "P53091", "MCM6", "P50874", "ORC5", "P29496", "MCM5", "P54790", "ORC3" ] }, "reaction_10760388": { "compartment": "compartment_7660", "id": "reaction_10760388", "reactome": "R-SCE-68917", "name": "Cdc45 associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760377", "species_10760305" ], "products": [ "species_10760379" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "P54791", "ORC4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3", "YLR103C", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P54791", "ORC4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10760386": { "compartment": "compartment_7660", "id": "reaction_10760386", "reactome": "R-SCE-68916", "name": "DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760379", "species_10760300" ], "products": [ "species_10760381" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P54791", "ORC4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3", "P22336", "YAR007C", "P26754", "YNL312W", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P22336", "YAR007C", "P54791", "ORC4", "P26754", "YNL312W", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10766866": { "compartment": "compartment_13231", "id": "reaction_10766866", "reactome": "R-SCE-193666", "name": "Active JNK moves to the nucleus and phosphorylates different transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765974" ], "products": [ "species_10765931" ], "modifiers": [], "additional_components": [ "YPR054W", "YPR054W" ] }, "reaction_10775479": { "compartment": "compartment_7660", "id": "reaction_10775479", "reactome": "R-SCE-3318486", "name": "KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_113560" ], "products": [ "species_2485002", "species_10775464" ], "modifiers": [ [ "species_10775476", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q12311", "YPR031W", "Q08465", "YOR064C", "Q08649", "YOR244W", "P50947", "YNL097C", "P38806", "YHR090C", "P47128", "YJR082C" ] }, "reaction_10775918": { "compartment": "compartment_7660", "id": "reaction_10775918", "reactome": "R-SCE-3662318", "name": "Type B histone acetlytransferase complex acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763701", "species_113560" ], "products": [ "species_2485002", "species_10775881" ], "modifiers": [ [ "species_10775915", "catalyst" ] ], "additional_components": [ "YBR009C", "YBR009C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P39984", "YEL056W", "Q12363", "YOR230W", "P13712", "YBR195C", "Q12341", "YPL001W" ] }, "reaction_10775460": { "compartment": "compartment_7660", "id": "reaction_10775460", "reactome": "R-SCE-3318415", "name": "ATF2 acetylates histone H2B, H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775434", "species_113560" ], "products": [ "species_2485002", "species_10775457" ], "modifiers": [ [ "species_10765915", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P02293", "YDR224C", "P02294", "YBL002W", "P02309", "YBR009C", "P02293", "YDR224C", "P39970", "YER045C", "P40535", "YIL036W", "Q02100", "YNL167C" ] }, "reaction_10775428": { "compartment": "compartment_7660", "id": "reaction_10775428", "reactome": "R-SCE-3318413", "name": "KAT7-containing ING4/5 complexes acetylate Me3K-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774208", "species_113560" ], "products": [ "species_2485002", "species_10775382" ], "modifiers": [ [ "species_10775425", "catalyst" ] ], "additional_components": [ "YKL049C", "YKL049C", "Q08465", "YOR064C", "Q08649", "YOR244W", "P50947", "YNL097C", "P38806", "YHR090C", "P47128", "YJR082C" ] }, "reaction_10764336": { "compartment": "compartment_7660", "id": "reaction_10764336", "reactome": "R-SCE-77069", "name": "RNA Polymerase II CTD (phosphorylated) binds to CE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764328", "species_10764334" ], "products": [ "species_10764330" ], "modifiers": [], "additional_components": [ "YGL130W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q01159", "YGL130W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10764381": { "compartment": "compartment_7660", "id": "reaction_10764381", "reactome": "R-SCE-77085", "name": "Dissociation of transcript with 5'-GMP from GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764374" ], "products": [ "species_10764379" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764377": { "compartment": "compartment_7660", "id": "reaction_10764377", "reactome": "R-SCE-77083", "name": "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764369" ], "products": [ "species_10764374" ], "modifiers": [ [ "species_10764369", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "species_113578", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "species_113578", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764360": { "compartment": "compartment_7660", "id": "reaction_10764360", "reactome": "R-SCE-77077", "name": "Capping complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_72084", "species_10764354", "species_29428" ], "products": [ "species_10764358" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764365": { "compartment": "compartment_7660", "id": "reaction_10764365", "reactome": "R-SCE-77078", "name": "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764358" ], "products": [ "species_113550", "species_10764362" ], "modifiers": [ [ "species_10764358", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764332": { "compartment": "compartment_7660", "id": "reaction_10764332", "reactome": "R-SCE-77068", "name": "Activation of GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764330" ], "products": [ "species_10764330" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q01159", "YGL130W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q01159", "YGL130W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10764386": { "compartment": "compartment_7660", "id": "reaction_10764386", "reactome": "R-SCE-77090", "name": "Methylation of GMP-cap by RNA Methyltransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764379", "species_77087" ], "products": [ "species_10762304", "species_10764383", "species_10764352", "species_10763293", "species_77502" ], "modifiers": [ [ "species_10764379", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P32783", "YBR236C", "Q01159", "YGL130W", "YML010W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764388": { "compartment": "compartment_7660", "id": "reaction_10764388", "reactome": "R-SCE-77094", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762228", "species_10762223" ], "products": [ "species_10762230" ], "modifiers": [], "additional_components": [ "YMR125W", "YPL178W", "P34160", "YMR125W", "Q08920", "YPL178W" ] }, "reaction_10764356": { "compartment": "compartment_7660", "id": "reaction_10764356", "reactome": "R-SCE-77073", "name": "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764330", "species_10764352", "species_10764346" ], "products": [ "species_10764354" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q01159", "YGL130W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "YML010W", "YBR236C", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764372": { "compartment": "compartment_7660", "id": "reaction_10764372", "reactome": "R-SCE-77081", "name": "Formation of the CE:GMP intermediate complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113571", "species_10764362" ], "products": [ "species_111349", "species_10764369" ], "modifiers": [ [ "species_10764362", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "species_113578", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764390": { "compartment": "compartment_7660", "id": "reaction_10764390", "reactome": "R-SCE-77095", "name": "Recognition and binding of the mRNA cap by the cap-binding complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762304", "species_10762230" ], "products": [ "species_10762306" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P34160", "YMR125W", "Q08920", "YPL178W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764820": { "compartment": "compartment_7660", "id": "reaction_10764820", "reactome": "R-SCE-110322", "name": "Formation of Pol zeta complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764773", "species_10764778" ], "products": [ "species_10764780" ], "modifiers": [], "additional_components": [ "YPL167C", "YIL139C", "P38927", "YIL139C", "P14284", "YPL167C" ] }, "reaction_10764789": { "compartment": "compartment_7660", "id": "reaction_10764789", "reactome": "R-SCE-110311", "name": "POLZ extends translesion synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764782", "species_30555" ], "products": [ "species_10764780", "species_10764786", "species_113541" ], "modifiers": [ [ "species_10764782", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38927", "YIL139C", "P14284", "YPL167C", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C" ] }, "reaction_10778576": { "compartment": "compartment_7660", "id": "reaction_10778576", "reactome": "R-SCE-5656158", "name": "POLZ elongates POLI-incorporated dNMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778564", "species_30555" ], "products": [ "species_10764780", "species_113541", "species_10778573", "species_10764742" ], "modifiers": [ [ "species_10778564", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38927", "YIL139C", "P14284", "YPL167C", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_109496", "P38629", "YNL290W", "YOR346W", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C" ] }, "reaction_10778296": { "compartment": "compartment_7660", "id": "reaction_10778296", "reactome": "R-SCE-5652151", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764780", "species_10764765" ], "products": [ "species_10764782" ], "modifiers": [], "additional_components": [ "P38927", "YIL139C", "P14284", "YPL167C", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C" ] }, "reaction_10764759": { "compartment": "compartment_7660", "id": "reaction_10764759", "reactome": "R-SCE-110307", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764755", "species_10764742" ], "products": [ "species_10764757" ], "modifiers": [], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "YOR346W", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10778567": { "compartment": "compartment_7660", "id": "reaction_10778567", "reactome": "R-SCE-5656148", "name": "POLI incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10778558" ], "products": [ "species_10778564", "species_113541" ], "modifiers": [ [ "species_10778558", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C" ] }, "reaction_10778548": { "compartment": "compartment_7660", "id": "reaction_10778548", "reactome": "R-SCE-5655965", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10778536" ], "products": [ "species_10764780", "species_10778545", "species_113541", "species_10764742" ], "modifiers": [ [ "species_10778536", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527", "P38927", "YIL139C", "P14284", "YPL167C", "P38630", "YOR217W", "P40339", "YOL094C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527", "YOR346W", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527" ] }, "reaction_10764768": { "compartment": "compartment_7660", "id": "reaction_10764768", "reactome": "R-SCE-110308", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10764757" ], "products": [ "species_10764765" ], "modifiers": [ [ "species_10764757", "catalyst" ] ], "additional_components": [ "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10778539": { "compartment": "compartment_7660", "id": "reaction_10778539", "reactome": "R-SCE-5655892", "name": "POLK incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10778530" ], "products": [ "species_10778536", "species_113541" ], "modifiers": [ [ "species_10778530", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38927", "YIL139C", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38927", "YIL139C", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527" ] }, "reaction_10773254": { "compartment": "compartment_70101", "id": "reaction_10773254", "reactome": "R-SCE-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_264618" ], "products": [ "species_29370", "species_1524071" ], "modifiers": [ [ "species_10773251", "catalyst" ] ], "additional_components": [ "P20485", "YLR133W", "Q03764", "YDR147W" ] }, "reaction_10773327": { "compartment": "compartment_12045", "id": "reaction_10773327", "reactome": "R-SCE-1483203", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_29372", "species_1500596" ], "modifiers": [ [ "species_10773324", "catalyst" ] ], "additional_components": [ "P32567", "YMR165C", "species_109496" ] }, "reaction_10773195": { "compartment": "compartment_12045", "id": "reaction_10773195", "reactome": "R-SCE-1482961", "name": "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524060", "species_1500596" ], "products": [ "species_109395", "species_426925" ], "modifiers": [ [ "species_10773192", "catalyst" ] ], "additional_components": [ "P17898", "YNL130C", "P22140", "YHR123W", "species_113527", "species_109496" ] }, "reaction_10773296": { "compartment": "compartment_12045", "id": "reaction_10773296", "reactome": "R-SCE-1483174", "name": "PE is methylated to PC by PEMT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_71284" ], "products": [ "species_426925", "species_71285" ], "modifiers": [ [ "species_10773293", "catalyst" ] ], "additional_components": [ "YJR073C" ] }, "reaction_10768148": { "compartment": "compartment_70101", "id": "reaction_10768148", "reactome": "R-SCE-264622", "name": "Cho is acetylated to AcCho by CHAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618", "species_76183" ], "products": [ "species_76194", "species_264643" ], "modifiers": [ [ "species_10768145", "catalyst" ] ], "additional_components": [ "YML042W" ] }, "reaction_10773219": { "compartment": "compartment_20699", "id": "reaction_10773219", "reactome": "R-SCE-1482973", "name": "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524057", "species_1524060" ], "products": [ "species_109395", "species_429785" ], "modifiers": [ [ "species_10773216", "catalyst" ] ], "additional_components": [ "P17898", "YNL130C", "P22140", "YHR123W", "species_113527", "species_109496" ] }, "reaction_10781570": { "compartment": "compartment_876", "id": "reaction_10781570", "reactome": "R-SCE-5694485", "name": "ABHD3 hydrolyses LPC(14:0) to 1AGPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694502", "species_29356" ], "products": [ "species_1861754", "species_5694457" ], "modifiers": [ [ "species_10781567", "catalyst" ] ], "additional_components": [ "Q03649", "YMR210W", "Q02891", "YPL095C", "P38295", "YBR177C" ] }, "reaction_10773273": { "compartment": "compartment_12045", "id": "reaction_10773273", "reactome": "R-SCE-1483081", "name": "PCho and CTP are condensed to CDP-Cho by PCYT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_1524071" ], "products": [ "species_111294", "species_1524060" ], "modifiers": [ [ "species_10773270", "catalyst" ] ], "additional_components": [ "P13259", "YGR202C" ] }, "reaction_10761101": { "compartment": "compartment_7660", "id": "reaction_10761101", "reactome": "R-SCE-69608", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761051", "species_29358" ], "products": [ "species_113582", "species_10761063" ], "modifiers": [ [ "species_10761098", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "YDL101C" ] }, "reaction_10761061": { "compartment": "compartment_70101", "id": "reaction_10761061", "reactome": "R-SCE-69600", "name": "Proteolytic degradation of ubiquitinated-Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761059" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P23748", "YMR036C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10761089": { "compartment": "compartment_7660", "id": "reaction_10761089", "reactome": "R-SCE-69604", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761051", "species_29358" ], "products": [ "species_113582", "species_10761063" ], "modifiers": [ [ "species_10761086", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "P36002", "YKL198C", "P47116", "YJR059W", "P06782", "YDR477W" ] }, "reaction_10765884": { "compartment": "compartment_947587", "id": "reaction_10765884", "reactome": "R-SCE-167415", "name": "G-protein alpha subunit is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764870", "species_29420" ], "products": [ "species_29438", "species_10764965" ], "modifiers": [ [ "species_10764864", "catalyst" ] ], "additional_components": [ "species_29438", "P10823", "YER020W", "species_29420", "P10823", "YER020W", "YER020W" ] }, "reaction_10777703": { "compartment": "compartment_12045", "id": "reaction_10777703", "reactome": "R-SCE-5362412", "name": "SYVN1 ubiquitinates Hh C-terminal fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777696", "species_10760634" ], "products": [ "species_10777700" ], "modifiers": [ [ "species_10777696", "catalyst" ] ], "additional_components": [ "P38307", "YBR201W", "Q05787", "YLR207W", "Q99220", "YDR057W", "Q08109", "YOL013C", "P25694", "YDL126C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38307", "YBR201W", "Q05787", "YLR207W", "Q99220", "YDR057W", "Q08109", "YOL013C", "P25694", "YDL126C", "P38307", "YBR201W", "Q05787", "YLR207W", "Q99220", "YDR057W", "Q08109", "YOL013C", "P25694", "YDL126C" ] }, "reaction_10777910": { "compartment": "compartment_5263232", "id": "reaction_10777910", "reactome": "R-SCE-5610749", "name": "cAMP dissociates PKA, promoting GLI processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10777906" ], "products": [ "species_10777900", "species_10777908" ], "modifiers": [], "additional_components": [ "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "P05986", "YKL166C", "P06245", "YPL203W", "P06244", "YJL164C", "P07278", "YIL033C", "species_30389" ] }, "reaction_10768868": { "compartment": "compartment_17947", "id": "reaction_10768868", "reactome": "R-SCE-382613", "name": "PEX-19 docks ABCD1/D2/D3 to peroximal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768844", "species_10768866" ], "products": [ "species_10768844", "species_10768836", "species_10768864" ], "modifiers": [], "additional_components": [ "YDR329C", "Q07418", "YDL065C", "P34230", "YKL188C", "P41909", "YPL147W", "YDR329C", "P34230", "YKL188C", "P41909", "YPL147W", "YDL065C" ] }, "reaction_10772903": { "compartment": "compartment_70101", "id": "reaction_10772903", "reactome": "R-SCE-1454916", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_1454930" ], "products": [ "species_29370", "species_1454919", "species_29372" ], "modifiers": [ [ "species_10772900", "catalyst" ] ], "additional_components": [ "P14772", "YLL015W", "P39109", "YDR135C", "P32386", "YLL048C", "P38735", "YHL035C", "P53049", "YGR281W", "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10768883": { "compartment": "compartment_876", "id": "reaction_10768883", "reactome": "R-SCE-383190", "name": "HCO3- transport through ion channel", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_29356" ], "products": [ "species_29370", "species_425425", "species_29372" ], "modifiers": [ [ "species_10768880", "catalyst" ] ], "additional_components": [ "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10786350": { "compartment": "compartment_876", "id": "reaction_10786350", "reactome": "R-SCE-8866851", "name": "CFTR transits to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786344" ], "products": [ "species_10768880" ], "modifiers": [], "additional_components": [ "P0CE68", "YKR103W", "P12866", "YKL209C", "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10768816": { "compartment": "compartment_70616", "id": "reaction_10768816", "reactome": "R-SCE-382560", "name": "ABC7, mABC1 and mABC2 mediate heme transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_189444", "species_113593" ], "products": [ "species_113548", "species_113581", "species_71185" ], "modifiers": [ [ "species_10768813", "catalyst" ] ], "additional_components": [ "P40416", "ATM1" ] }, "reaction_10786348": { "compartment": "compartment_70101", "id": "reaction_10786348", "reactome": "R-SCE-8866553", "name": "misfolded CFTR is degraded by the 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786346" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P0CE68", "YKR103W", "P12866", "YKL209C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10779080": { "compartment": "compartment_70101", "id": "reaction_10779080", "reactome": "R-SCE-5678863", "name": "CFTR transports Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_352022", "species_29356" ], "products": [ "species_29370", "species_188972", "species_29372" ], "modifiers": [ [ "species_10768880", "catalyst" ] ], "additional_components": [ "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10768839": { "compartment": "compartment_17947", "id": "reaction_10768839", "reactome": "R-SCE-382575", "name": "ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_382577", "species_113592", "species_29356" ], "products": [ "species_29370", "species_382571", "species_29372" ], "modifiers": [ [ "species_10768836", "catalyst" ] ], "additional_components": [ "P34230", "YKL188C", "P41909", "YPL147W" ] }, "reaction_10789057": { "compartment": "compartment_984", "id": "reaction_10789057", "reactome": "R-SCE-9673053", "name": "PM20D1 transforms oleoyl-phe from oleate and phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351993", "species_9673048" ], "products": [ "species_9673044", "species_109276" ], "modifiers": [ [ "species_10789054", "catalyst" ] ], "additional_components": [ "YJL172W" ] }, "reaction_10789059": { "compartment": "compartment_984", "id": "reaction_10789059", "reactome": "R-SCE-9673054", "name": "PM20D1 hydrolyzes oleoyl-phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9673044", "species_109276" ], "products": [ "species_351993", "species_9673048" ], "modifiers": [ [ "species_10789054", "catalyst" ] ], "additional_components": [ "YJL172W" ] }, "reaction_10784879": { "compartment": "compartment_20699", "id": "reaction_10784879", "reactome": "R-SCE-6811415", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784367", "species_10784862" ], "products": [ "species_10784864" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P01123", "YFL038C", "species_29438", "P47102", "YJR031C", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "species_29438" ] }, "reaction_10784874": { "compartment": "compartment_20699", "id": "reaction_10784874", "reactome": "R-SCE-6811412", "name": "Active ARF recruits coatomer to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784870", "species_10784438" ], "products": [ "species_10784872" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P43621", "YFR051C", "P53600", "YPL010W", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P41810", "YDR238C", "P47102", "YJR031C", "P11076", "YDL192W", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P41810", "YDR238C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W" ] }, "reaction_10784939": { "compartment": "compartment_20699", "id": "reaction_10784939", "reactome": "R-SCE-6811417", "name": "ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784935", "species_10784925", "species_10784872", "species_10784923", "species_10784463" ], "products": [ "species_10784937" ], "modifiers": [], "additional_components": [ "P18414", "YBL040C", "P38819", "YHR110W", "P32803", "YGL200C", "P53198", "YGL002W", "P53337", "YGR284C", "P54837", "YML012W", "Q05359", "YAR002C-A", "YLR268W", "P47102", "YJR031C", "P11076", "YDL192W", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P41810", "YDR238C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P38819", "YHR110W", "P32803", "YGL200C", "P53198", "YGL002W", "P39704", "YAL007C", "Q12403", "YDL018C", "P54837", "YML012W", "Q12450", "YOR016C", "Q05359", "YAR002C-A", "P32572", "YNL204C", "P38682", "YER122C", "P35197", "YDL226C", "P32803", "YGL200C", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P53337", "YGR284C", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P22214", "YLR268W", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C" ] }, "reaction_10784952": { "compartment": "compartment_20699", "id": "reaction_10784952", "reactome": "R-SCE-6811418", "name": "ARFGAPs stimulate ARF GTPase activity at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784937" ], "products": [ "species_10784949", "species_10784367", "species_10784463", "species_10784385" ], "modifiers": [ [ "species_10784937", "catalyst" ] ], "additional_components": [ "P32803", "YGL200C", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P53337", "YGR284C", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P22214", "YLR268W", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C", "P32803", "YGL200C", "P53198", "YGL002W", "P39704", "YAL007C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P22214", "YLR268W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P43621", "YFR051C", "P53337", "YGR284C", "P53600", "YPL010W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "Q12403", "YDL018C", "P32074", "YNL287W", "P41811", "YGL137W", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P32572", "YNL204C", "P38682", "YER122C", "P35197", "YDL226C", "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "P32803", "YGL200C", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P53337", "YGR284C", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P22214", "YLR268W", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C" ] }, "reaction_10784982": { "compartment": "compartment_12045", "id": "reaction_10784982", "reactome": "R-SCE-6811425", "name": "NSF and SNAPs bind cis-SNARE at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10784980" ], "products": [ "species_10784971" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P22214", "YLR268W", "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W" ] }, "reaction_10784974": { "compartment": "compartment_12045", "id": "reaction_10784974", "reactome": "R-SCE-6811422", "name": "NSF ATPase activity dissociates cis-SNARE at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10784971" ], "products": [ "species_10769994", "species_10781444", "species_10784957", "species_10784962", "species_10767816", "species_29372", "species_10784967" ], "modifiers": [ [ "species_10784971", "catalyst" ] ], "additional_components": [ "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W", "YBL050W", "P18759", "YBR080C", "YDR498C", "YOR075W", "YLR268W", "YGL098W", "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W" ] }, "reaction_10784868": { "compartment": "compartment_20699", "id": "reaction_10784868", "reactome": "R-SCE-6811411", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784864", "species_10784385" ], "products": [ "species_10784866" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "species_29438", "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "species_29420", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438" ] }, "reaction_10785080": { "compartment": "compartment_12045", "id": "reaction_10785080", "reactome": "R-SCE-6811427", "name": "COPI vesicle uncoating at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785078" ], "products": [ "species_10785076", "species_10784438", "species_10784980", "species_10785042", "species_10781345" ], "modifiers": [], "additional_components": [ "P32803", "YGL200C", "P53198", "YGL002W", "P39704", "YAL007C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P41810", "YDR238C", "P22214", "YLR268W", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P33891", "YGL145W", "P38819", "YHR110W", "P43621", "YFR051C", "P53146", "YGL098W", "P28791", "YDR498C", "P53337", "YGR284C", "P41834", "YOR075W", "P53600", "YPL010W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "Q12403", "YDL018C", "P53847", "YNL258C", "P32074", "YNL287W", "P41811", "YGL137W", "P18414", "YBL040C", "P38819", "YHR110W", "P32803", "YGL200C", "P53198", "YGL002W", "P53337", "YGR284C", "P54837", "YML012W", "Q05359", "YAR002C-A", "P43621", "YFR051C", "P53600", "YPL010W", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P41810", "YDR238C", "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P22214", "YLR268W", "P38819", "YHR110W", "P32803", "YGL200C", "P53198", "YGL002W", "P39704", "YAL007C", "Q12403", "YDL018C", "P54837", "YML012W", "Q12450", "YOR016C", "Q05359", "YAR002C-A", "species_29420", "P01123", "YFL038C" ] }, "reaction_10784877": { "compartment": "compartment_20699", "id": "reaction_10784877", "reactome": "R-SCE-6811414", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10784866" ], "products": [ "species_10784870", "species_29420" ], "modifiers": [ [ "species_10784866", "catalyst" ] ], "additional_components": [ "species_29420", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "species_29420", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438" ] }, "reaction_10769704": { "compartment": "compartment_876", "id": "reaction_10769704", "reactome": "R-SCE-426130", "name": "SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113", "species_188972" ], "products": [ "species_83910", "species_352022" ], "modifiers": [ [ "species_10769701", "catalyst" ] ], "additional_components": [ "YBR235W" ] }, "reaction_10769699": { "compartment": "compartment_876", "id": "reaction_10769699", "reactome": "R-SCE-426086", "name": "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113", "species_188972", "species_74126" ], "products": [ "species_29804", "species_83910", "species_352022" ], "modifiers": [ [ "species_10769694", "catalyst" ] ], "additional_components": [ "YBR235W" ] }, "reaction_10774613": { "compartment": "compartment_70101", "id": "reaction_10774613", "reactome": "R-SCE-2534096", "name": "METAP1/2 demethylates GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774594" ], "products": [ "species_174390", "species_10774582" ], "modifiers": [ [ "species_10774610", "catalyst" ] ], "additional_components": [ "YER020W", "YER020W", "Q01662", "YLR244C", "P38174", "YBL091C", "species_880069" ] }, "reaction_10774654": { "compartment": "compartment_70101", "id": "reaction_10774654", "reactome": "R-SCE-2586748", "name": "GUCA binds Ca2+ to form GUCA:Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_10774640" ], "products": [ "species_10774652" ], "modifiers": [], "additional_components": [ "YDR373W", "species_74016", "Q06389", "YDR373W" ] }, "reaction_10774592": { "compartment": "compartment_70101", "id": "reaction_10774592", "reactome": "R-SCE-2534087", "name": "NMT1/2 transfer MYS to GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2534019", "species_10774582" ], "products": [ "species_76194", "species_10763522" ], "modifiers": [ [ "species_10774587", "catalyst" ] ], "additional_components": [ "YER020W", "YER020W", "YLR195C" ] }, "reaction_10763540": { "compartment": "compartment_2514888", "id": "reaction_10763540", "reactome": "R-SCE-74059", "name": "PDE6 hydrolyses cGMP to GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30991" ], "products": [ "species_113578" ], "modifiers": [ [ "species_10763537", "catalyst" ] ], "additional_components": [ "P06776", "YOR360C", "species_29438", "P10823", "YER020W" ] }, "reaction_10774322": { "compartment": "compartment_70101", "id": "reaction_10774322", "reactome": "R-SCE-2465940", "name": "atRAL is reduced to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_975622" ], "products": [ "species_29366", "species_2473607" ], "modifiers": [ [ "species_10774319", "catalyst" ] ], "additional_components": [ "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C" ] }, "reaction_10765352": { "compartment": "compartment_7660", "id": "reaction_10765352", "reactome": "R-SCE-156678", "name": "Activation of Cdc25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765340", "species_113592" ], "products": [ "species_29370", "species_10765343" ], "modifiers": [ [ "species_10765349", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "YMR001C" ] }, "reaction_10765477": { "compartment": "compartment_7660", "id": "reaction_10765477", "reactome": "R-SCE-162657", "name": "Inactivation of Myt1 kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10765469" ], "products": [ "species_113582", "species_10765472" ], "modifiers": [ [ "species_10765474", "catalyst" ] ], "additional_components": [ "YJL187C", "YJL187C", "YMR001C" ] }, "reaction_10771316": { "compartment": "compartment_70101", "id": "reaction_10771316", "reactome": "R-SCE-893616", "name": "glutamine + pyruvate => 2-oxoglutaramate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29398" ], "products": [ "species_893598", "species_29432" ], "modifiers": [ [ "species_10771307", "catalyst" ] ], "additional_components": [ "P47039", "YJL060W" ] }, "reaction_10781888": { "compartment": "compartment_5460", "id": "reaction_10781888", "reactome": "R-SCE-6783939", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113529", "species_113590" ], "products": [ "species_379717", "species_113526" ], "modifiers": [ [ "species_10781885", "catalyst" ] ], "additional_components": [ "P32263", "YER023W" ] }, "reaction_10761570": { "compartment": "compartment_5460", "id": "reaction_10761570", "reactome": "R-SCE-70664", "name": "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113529", "species_113590" ], "products": [ "species_379717", "species_113526" ], "modifiers": [ [ "species_10761567", "catalyst" ] ], "additional_components": [ "P32263", "YER023W" ] }, "reaction_10761572": { "compartment": "compartment_5460", "id": "reaction_10761572", "reactome": "R-SCE-70666", "name": "glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31339", "species_113552" ], "products": [ "species_113594", "species_113585" ], "modifiers": [ [ "species_10761557", "catalyst" ] ], "additional_components": [ "P07991", "YLR438W" ] }, "reaction_10771117": { "compartment": "compartment_5460", "id": "reaction_10771117", "reactome": "R-SCE-508040", "name": "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_113552", "species_113529", "species_113593" ], "products": [ "species_31339", "species_113548", "species_113563", "species_113581" ], "modifiers": [ [ "species_10771114", "catalyst" ] ], "additional_components": [ "P54885", "YOR323C" ] }, "reaction_10781895": { "compartment": "compartment_70101", "id": "reaction_10781895", "reactome": "R-SCE-6783955", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_35305" ], "products": [ "species_29366", "species_113538" ], "modifiers": [ [ "species_10781892", "catalyst" ] ], "additional_components": [ "P32263", "YER023W" ] }, "reaction_10761527": { "compartment": "compartment_70101", "id": "reaction_10761527", "reactome": "R-SCE-70606", "name": "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_31633" ], "products": [ "species_29370", "species_29472", "species_29372" ], "modifiers": [ [ "species_10761524", "catalyst" ] ], "additional_components": [ "P32288", "YPR035W" ] }, "reaction_10761529": { "compartment": "compartment_5460", "id": "reaction_10761529", "reactome": "R-SCE-70613", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113587" ], "products": [ "species_113594", "species_113553" ], "modifiers": [ [ "species_10761497", "catalyst" ] ], "additional_components": [ "Q01802", "YKL106W" ] }, "reaction_10789049": { "compartment": "compartment_7660", "id": "reaction_10789049", "reactome": "R-SCE-9671145", "name": "DKC1 binds SHQ1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765537", "species_10789045" ], "products": [ "species_10789047" ], "modifiers": [], "additional_components": [ "YLR175W", "YIL104C", "P33322", "YLR175W", "P40486", "YIL104C" ] }, "reaction_10769750": { "compartment": "compartment_876", "id": "reaction_10769750", "reactome": "R-SCE-427555", "name": "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648", "species_351626" ], "products": [ "species_70106", "species_174375" ], "modifiers": [ [ "species_10769747", "catalyst" ] ], "additional_components": [ "P53394", "YPR003C" ] }, "reaction_10766300": { "compartment": "compartment_70101", "id": "reaction_10766300", "reactome": "R-SCE-174392", "name": "PAPSS1,2 transfer SO4(2-) group to ATP to form APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174375", "species_113592" ], "products": [ "species_174370", "species_111294" ], "modifiers": [ [ "species_10766269", "catalyst" ] ], "additional_components": [ "YKL001C" ] }, "reaction_10766274": { "compartment": "compartment_70101", "id": "reaction_10766274", "reactome": "R-SCE-174389", "name": "PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174370", "species_113592" ], "products": [ "species_158471", "species_29370" ], "modifiers": [ [ "species_10766269", "catalyst" ] ], "additional_components": [ "YKL001C" ] }, "reaction_10778591": { "compartment": "compartment_7660", "id": "reaction_10778591", "reactome": "R-SCE-5661121", "name": "KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778271", "species_113671", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776818" ], "modifiers": [ [ "species_10776825", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YBR112C" ] }, "reaction_10778580": { "compartment": "compartment_7660", "id": "reaction_10778580", "reactome": "R-SCE-5661116", "name": "KDM5A-D demethylate Me3K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777406", "species_113671", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776782" ], "modifiers": [ [ "species_10776810", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03214", "YMR176W", "P47156", "YJR119C" ] }, "reaction_10775027": { "compartment": "compartment_7660", "id": "reaction_10775027", "reactome": "R-SCE-3214912", "name": "KDM1A, KDM1B demethylate MeK5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775017" ], "products": [ "species_10775019", "species_29478" ], "modifiers": [ [ "species_10775024", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YMR020W" ] }, "reaction_10778578": { "compartment": "compartment_7660", "id": "reaction_10778578", "reactome": "R-SCE-5661114", "name": "KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10778230", "species_113685" ], "products": [ "species_10776742", "species_159942", "species_159939", "species_29478" ], "modifiers": [ [ "species_10776754", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03833", "YDR096W", "P39956", "YER169W" ] }, "reaction_10778589": { "compartment": "compartment_7660", "id": "reaction_10778589", "reactome": "R-SCE-5661120", "name": "KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10776843", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776759" ], "modifiers": [ [ "species_10776777", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03833", "YDR096W", "P39956", "YER169W" ] }, "reaction_10776757": { "compartment": "compartment_7660", "id": "reaction_10776757", "reactome": "R-SCE-4722133", "name": "KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776742", "species_113671", "species_113685" ], "products": [ "species_10775019", "species_159942", "species_159939", "species_29478" ], "modifiers": [ [ "species_10776754", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03833", "YDR096W", "P39956", "YER169W" ] }, "reaction_10776780": { "compartment": "compartment_7660", "id": "reaction_10776780", "reactome": "R-SCE-4724279", "name": "KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10776759", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776761" ], "modifiers": [ [ "species_10776777", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03833", "YDR096W", "P39956", "YER169W" ] }, "reaction_10776813": { "compartment": "compartment_7660", "id": "reaction_10776813", "reactome": "R-SCE-4754181", "name": "KDM5A-D demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10776782" ], "products": [ "species_159942", "species_10775017", "species_159939", "species_29478" ], "modifiers": [ [ "species_10776810", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03214", "YMR176W", "P47156", "YJR119C" ] }, "reaction_10778593": { "compartment": "compartment_7660", "id": "reaction_10778593", "reactome": "R-SCE-5661123", "name": "KDM1A, KDM1B demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776782" ], "products": [ "species_10775017", "species_29478" ], "modifiers": [ [ "species_10775024", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YMR020W" ] }, "reaction_10776830": { "compartment": "compartment_7660", "id": "reaction_10776830", "reactome": "R-SCE-4754187", "name": "KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10776818", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776823" ], "modifiers": [ [ "species_10776825", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YBR112C" ] }, "reaction_10770574": { "compartment": "compartment_7660", "id": "reaction_10770574", "reactome": "R-SCE-448955", "name": "Phosphorylation of MEF2 proteins by p38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10770541", "species_10770545" ], "products": [ "species_113582", "species_10770571" ], "modifiers": [ [ "species_10770545", "catalyst" ] ], "additional_components": [ "P38128", "YBR182C", "Q12224", "YPL089C", "P32485", "YLR113W", "P32485", "YLR113W", "P38128", "YBR182C", "Q12224", "YPL089C", "P32485", "YLR113W" ] }, "reaction_10769182": { "compartment": "compartment_17940", "id": "reaction_10769182", "reactome": "R-SCE-392749", "name": "Transport of L1 into endosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769180" ], "products": [ "species_10769180" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C" ] }, "reaction_10770284": { "compartment": "compartment_70101", "id": "reaction_10770284", "reactome": "R-SCE-445079", "name": "Phosphorylation of L1 by ERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10769180", "species_10764614" ], "products": [ "species_29370", "species_10770282" ], "modifiers": [ [ "species_10764614", "catalyst" ] ], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "YBL016W", "P16892", "YBL016W", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "YBL016W" ] }, "reaction_10764609": { "compartment": "compartment_70101", "id": "reaction_10764609", "reactome": "R-SCE-109860", "name": "MAP2K1 phosphorylates MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10764572" ], "products": [ "species_29370", "species_10764600" ], "modifiers": [ [ "species_10764572", "catalyst" ], [ "species_10764605", "inhibitor" ] ], "additional_components": [ "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "YDL159W" ] }, "reaction_10767247": { "compartment": "compartment_7660", "id": "reaction_10767247", "reactome": "R-SCE-198756", "name": "ERK1/2 phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767221", "species_29358" ], "products": [ "species_113582", "species_10767227" ], "modifiers": [ [ "species_10767244", "catalyst" ] ], "additional_components": [ "YBR028C", "YBR028C", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10764619": { "compartment": "compartment_70101", "id": "reaction_10764619", "reactome": "R-SCE-109862", "name": "MAP2K2 phosphorylates MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764582", "species_113592" ], "products": [ "species_29370", "species_10764616" ], "modifiers": [ [ "species_10764582", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "P06784", "YDL159W", "P16892", "YBL016W", "P06784", "YDL159W", "P16892", "YBL016W", "P06784", "YDL159W" ] }, "reaction_10766423": { "compartment": "compartment_7660", "id": "reaction_10766423", "reactome": "R-SCE-176956", "name": "Formation of GINS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766419", "species_10766414", "species_10766404", "species_10766409" ], "products": [ "species_10766421" ], "modifiers": [], "additional_components": [ "YDR489W", "YOL146W", "YDR013W", "YJL072C", "Q12488", "YDR013W", "Q03406", "YDR489W", "P40359", "YJL072C", "Q12146", "YOL146W" ] }, "reaction_10787208": { "compartment": "compartment_12045", "id": "reaction_10787208", "reactome": "R-SCE-8941701", "name": "UGT1A10 transfers GlcA from UDP-GlcA to GCTN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8941723", "species_174384" ], "products": [ "species_158602", "species_8941725" ], "modifiers": [ [ "species_10765445", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10772692": { "compartment": "compartment_70101", "id": "reaction_10772692", "reactome": "R-SCE-1247910", "name": "CNDP2:2Mn2+ dimer hydrolyses CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1247904", "species_29356" ], "products": [ "species_29424", "species_111707" ], "modifiers": [ [ "species_10772689", "catalyst" ] ], "additional_components": [ "species_113527", "P43616", "YFR044C" ] }, "reaction_10788717": { "compartment": "compartment_17957", "id": "reaction_10788717", "reactome": "R-SCE-9632038", "name": "UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159160", "species_174384" ], "products": [ "species_158602", "species_159149" ], "modifiers": [ [ "species_10788714", "catalyst" ] ], "additional_components": [ "Q06321", "YLR189C" ] }, "reaction_10765464": { "compartment": "compartment_17957", "id": "reaction_10765464", "reactome": "R-SCE-159194", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159151", "species_174384" ], "products": [ "species_159160", "species_158602" ], "modifiers": [ [ "species_10765459", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10766342": { "compartment": "compartment_17957", "id": "reaction_10766342", "reactome": "R-SCE-174916", "name": "Formation of N-glucuronides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174384", "species_174932" ], "products": [ "species_158602", "species_174918" ], "modifiers": [ [ "species_10765459", "catalyst" ] ], "additional_components": [ "CHEBI:41774", "CHEBI:17688", "CHEBI:32663", "CHEBI:63860", "YLR189C" ] }, "reaction_10766297": { "compartment": "compartment_70101", "id": "reaction_10766297", "reactome": "R-SCE-174391", "name": "MAT1A multimers transfer Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_174390", "species_29356" ], "products": [ "species_111294", "species_71284", "species_29372" ], "modifiers": [ [ "species_10766294", "catalyst" ] ], "additional_components": [ "P19358", "YDR502C", "species_74126", "species_109496", "P10659", "YLR180W" ] }, "reaction_10765462": { "compartment": "compartment_17957", "id": "reaction_10765462", "reactome": "R-SCE-159179", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159160", "species_174384" ], "products": [ "species_158602", "species_159149" ], "modifiers": [ [ "species_10765459", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10766310": { "compartment": "compartment_70101", "id": "reaction_10766310", "reactome": "R-SCE-174394", "name": "GSS:Mg2+ dimer synthesizes GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_174393", "species_113592" ], "products": [ "species_29370", "species_29450", "species_29372" ], "modifiers": [ [ "species_10766307", "catalyst" ], [ "species_29450", "inhibitor" ] ], "additional_components": [ "Q08220", "YOL049W", "species_109496" ] }, "reaction_10766322": { "compartment": "compartment_70101", "id": "reaction_10766322", "reactome": "R-SCE-174401", "name": "AHCY:NAD+ tetramer hydrolyses AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71285", "species_29356" ], "products": [ "species_174369", "species_83909" ], "modifiers": [ [ "species_10766319", "catalyst" ] ], "additional_components": [ "P39954", "YER043C", "species_113526" ] }, "reaction_10787391": { "compartment": "compartment_876", "id": "reaction_10787391", "reactome": "R-SCE-8943279", "name": "GGT dimers hydrolyse GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1247892", "species_109276" ], "products": [ "species_210382", "species_1247934" ], "modifiers": [ [ "species_10777790", "catalyst" ] ], "additional_components": [ "Q05902", "YLR299W" ] }, "reaction_10781250": { "compartment": "compartment_17957", "id": "reaction_10781250", "reactome": "R-SCE-5693724", "name": "ESD dimer hydrolyses S-FGSH to GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_5693723" ], "products": [ "species_158543", "species_194712" ], "modifiers": [ [ "species_10781247", "catalyst" ] ], "additional_components": [ "P40363", "YJL068C" ] }, "reaction_10783821": { "compartment": "compartment_70101", "id": "reaction_10783821", "reactome": "R-SCE-6800149", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6806829", "species_71284" ], "products": [ "species_6800127", "species_71285" ], "modifiers": [ [ "species_10783815", "catalyst" ] ], "additional_components": [ "P53738", "TRM112", "Q03920", "YDR140W" ] }, "reaction_10772702": { "compartment": "compartment_70101", "id": "reaction_10772702", "reactome": "R-SCE-1247935", "name": "OPLAH hydrolyses OPRO to L-Glu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1247942", "species_29356" ], "products": [ "species_29370", "species_29404", "species_29372" ], "modifiers": [ [ "species_10772699", "catalyst" ] ], "additional_components": [ "P28273", "YKL215C" ] }, "reaction_10788719": { "compartment": "compartment_17957", "id": "reaction_10788719", "reactome": "R-SCE-9632039", "name": "UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159151", "species_174384" ], "products": [ "species_159160", "species_158602" ], "modifiers": [ [ "species_10765441", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10761138": { "compartment": "compartment_70101", "id": "reaction_10761138", "reactome": "R-SCE-70286", "name": "UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29494", "species_29548" ], "products": [ "species_29410", "species_111294" ], "modifiers": [ [ "species_10761135", "catalyst" ] ], "additional_components": [ "P32861", "YKL035W" ] }, "reaction_10781969": { "compartment": "compartment_70101", "id": "reaction_10781969", "reactome": "R-SCE-6785928", "name": "CHAC1,2 cleaves GSH to OPRO and CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450" ], "products": [ "species_1247904", "species_1247942" ], "modifiers": [ [ "species_10781964", "catalyst" ] ], "additional_components": [ "YER163C" ] }, "reaction_10778676": { "compartment": "compartment_70101", "id": "reaction_10778676", "reactome": "R-SCE-5668545", "name": "NIK autophosphorylates on T559", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769138", "species_113592" ], "products": [ "species_29370", "species_10778673" ], "modifiers": [ [ "species_10769138", "catalyst" ] ], "additional_components": [ "YCR073C", "YCR073C", "YCR073C" ] }, "reaction_10778670": { "compartment": "compartment_70101", "id": "reaction_10778670", "reactome": "R-SCE-5668520", "name": "26Sproteasome degrades K48polyUb-NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778668" ], "products": [], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "YCR073C", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10784295": { "compartment": "compartment_70101", "id": "reaction_10784295", "reactome": "R-SCE-6805811", "name": "Release of SEPT4 from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784279" ], "products": [ "species_10784293" ], "modifiers": [], "additional_components": [ "P32457", "YLR314C", "Q07657", "YDL225W", "Q04921", "YDR218C", "P32468", "YHR107C", "P41901", "YGR059W", "P32458", "YJR076C", "P32457", "YLR314C", "Q07657", "YDL225W", "Q04921", "YDR218C", "P32468", "YHR107C", "P41901", "YGR059W", "P32458", "YJR076C" ] }, "reaction_10765222": { "compartment": "compartment_17906", "id": "reaction_10765222", "reactome": "R-SCE-114284", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765220" ], "products": [ "species_10765214" ], "modifiers": [], "additional_components": [ "P00045", "YEL039C", "P00044", "YJR048W", "P00045", "YEL039C", "P00044", "YJR048W" ] }, "reaction_10764147": { "compartment": "compartment_7660", "id": "reaction_10764147", "reactome": "R-SCE-75891", "name": "Abortive Initiation After Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764145" ], "products": [ "species_10763503", "species_75897", "species_10763293", "species_10762312" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P36100", "YKL028W", "P22139", "RPB10", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P06839", "RAD3", "P36100", "YKL028W", "P36145", "YKR062W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764072": { "compartment": "compartment_7660", "id": "reaction_10764072", "reactome": "R-SCE-75862", "name": "Fall Back to Closed Pre-initiation Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764062" ], "products": [ "species_10764070" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10765186": { "compartment": "compartment_7660", "id": "reaction_10765186", "reactome": "R-SCE-112434", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764352", "species_10764976" ], "products": [ "species_10764978" ], "modifiers": [], "additional_components": [ "YML010W", "YGR063C", "P27692", "YML010W", "P32914", "YGR063C" ] }, "reaction_10765190": { "compartment": "compartment_7660", "id": "reaction_10765190", "reactome": "R-SCE-113409", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765001" ], "products": [ "species_10765001" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P27692", "YML010W", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P32914", "YGR063C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10", "P41896", "YGR005C", "P20434", "RPB5", "P27692", "YML010W", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P32914", "YGR063C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10763507": { "compartment": "compartment_7660", "id": "reaction_10763507", "reactome": "R-SCE-73946", "name": "Abortive initiation after formation of the first phosphodiester bond", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763505" ], "products": [ "species_109877", "species_10763503", "species_10763491", "species_10763293", "species_10762312", "species_10763417", "species_10763422" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P36100", "YKL028W", "P36145", "YKR062W", "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P32774", "YKL058W", "P32773", "YOR194C", "YPR086W" ] }, "reaction_10764060": { "compartment": "compartment_7660", "id": "reaction_10764060", "reactome": "R-SCE-75856", "name": "Abortive Initiation Before Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764058" ], "products": [ "species_110068", "species_10763503", "species_10763491", "species_10763293", "species_10762312", "species_10763417", "species_10763422" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P36100", "YKL028W", "P36145", "YKR062W", "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P32774", "YKL058W", "P32773", "YOR194C", "YPR086W" ] }, "reaction_10765192": { "compartment": "compartment_7660", "id": "reaction_10765192", "reactome": "R-SCE-113411", "name": "2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765164" ], "products": [ "species_10765168" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765184": { "compartment": "compartment_7660", "id": "reaction_10765184", "reactome": "R-SCE-112430", "name": "Formation of P-TEFb complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765028", "species_10765006" ], "products": [ "species_10765030" ], "modifiers": [], "additional_components": [ "Q05949", "YLR226W", "P46962", "YJL006C", "YKL139W", "Q05949", "YLR226W", "Q03957", "YKL139W", "P46962", "YJL006C" ] }, "reaction_10765170": { "compartment": "compartment_7660", "id": "reaction_10765170", "reactome": "R-SCE-112392", "name": "Resumption of elongation after recovery from pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765168" ], "products": [ "species_10765164" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765198": { "compartment": "compartment_7660", "id": "reaction_10765198", "reactome": "R-SCE-113414", "name": "7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765164" ], "products": [ "species_10765164" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765182": { "compartment": "compartment_7660", "id": "reaction_10765182", "reactome": "R-SCE-112429", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765097", "species_10765092" ], "products": [ "species_10765099" ], "modifiers": [], "additional_components": [ "YGL207W", "YML069W", "P32558", "YGL207W", "Q04636", "YML069W" ] }, "reaction_10765174": { "compartment": "compartment_7660", "id": "reaction_10765174", "reactome": "R-SCE-112395", "name": "Abortive termination of elongation after arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765164" ], "products": [ "species_10765172" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765196": { "compartment": "compartment_7660", "id": "reaction_10765196", "reactome": "R-SCE-113413", "name": "TFIIS-mediated recovery of elongation from arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765164" ], "products": [ "species_10765164" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10761589": { "compartment": "compartment_70101", "id": "reaction_10761589", "reactome": "R-SCE-70692", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498" ], "products": [ "species_29610", "species_113528" ], "modifiers": [ [ "species_10761586", "catalyst" ] ], "additional_components": [ "YKL184W" ] }, "reaction_10768335": { "compartment": "compartment_70101", "id": "reaction_10768335", "reactome": "R-SCE-350598", "name": "Arginine<=>Agmatine+CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468" ], "products": [ "species_113528", "species_351164" ], "modifiers": [ [ "species_10768332", "catalyst" ] ], "additional_components": [ "YKL184W" ] }, "reaction_10768411": { "compartment": "compartment_70101", "id": "reaction_10768411", "reactome": "R-SCE-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353113", "species_29610" ], "products": [ "species_353106", "species_204635" ], "modifiers": [ [ "species_10768408", "catalyst" ] ], "additional_components": [ "YPR069C" ] }, "reaction_10768403": { "compartment": "compartment_70101", "id": "reaction_10768403", "reactome": "R-SCE-351208", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_204635", "species_76183" ], "products": [ "species_76194", "species_353555" ], "modifiers": [ [ "species_10768398", "catalyst" ] ], "additional_components": [ "Q06592", "YPR193C", "P39979", "YEL066W" ] }, "reaction_10768419": { "compartment": "compartment_70101", "id": "reaction_10768419", "reactome": "R-SCE-351222", "name": "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284" ], "products": [ "species_353113", "species_113528" ], "modifiers": [ [ "species_10768416", "catalyst" ] ], "additional_components": [ "YOL052C" ] }, "reaction_10768401": { "compartment": "compartment_70101", "id": "reaction_10768401", "reactome": "R-SCE-351207", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353560", "species_76183" ], "products": [ "species_76194", "species_353575" ], "modifiers": [ [ "species_10768398", "catalyst" ] ], "additional_components": [ "Q06592", "YPR193C", "P39979", "YEL066W" ] }, "reaction_10778699": { "compartment": "compartment_70101", "id": "reaction_10778699", "reactome": "R-SCE-5671737", "name": "p-T774-PKN1 binds CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765340", "species_10778027" ], "products": [ "species_10778697" ], "modifiers": [], "additional_components": [ "YMR036C", "YBL105C", "P23748", "YMR036C", "P24583", "YBL105C" ] }, "reaction_10778693": { "compartment": "compartment_70101", "id": "reaction_10778693", "reactome": "R-SCE-5668932", "name": "PAK2 phosphorylates myosin regulatory light chain (MRLC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778684", "species_113592" ], "products": [ "species_29370", "species_10778690" ], "modifiers": [ [ "species_10778151", "catalyst" ] ], "additional_components": [ "P08964", "YHR023W", "Q06580", "YPR188C", "P53141", "YGL106W", "P08964", "YHR023W", "Q06580", "YPR188C", "P53141", "YGL106W", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W" ] }, "reaction_10778117": { "compartment": "compartment_70101", "id": "reaction_10778117", "reactome": "R-SCE-5626469", "name": "GTP-bound RAC1 and CDC42 bind IQGAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778113", "species_10768894" ], "products": [ "species_10778115" ], "modifiers": [], "additional_components": [ "Q12280", "YPL242C", "species_29438", "P19073", "YLR229C", "Q12280", "YPL242C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10778702": { "compartment": "compartment_70101", "id": "reaction_10778702", "reactome": "R-SCE-5671749", "name": "p-T774-PKN1 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778697", "species_113592" ], "products": [ "species_29370", "species_10763798", "species_10778027" ], "modifiers": [ [ "species_10778697", "catalyst" ] ], "additional_components": [ "P23748", "YMR036C", "P24583", "YBL105C", "YMR036C", "YBL105C", "P23748", "YMR036C", "P24583", "YBL105C" ] }, "reaction_10778091": { "compartment": "compartment_7660", "id": "reaction_10778091", "reactome": "R-SCE-5625797", "name": "KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10778076" ], "products": [ "species_159942", "species_159939", "species_10776769", "species_29478", "species_10778088" ], "modifiers": [ [ "species_10778076", "catalyst" ] ], "additional_components": [ "Q03833", "YDR096W", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P39956", "YER169W", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "Q03833", "YDR096W", "P39956", "YER169W", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "Q03833", "YDR096W", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P39956", "YER169W", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117" ] }, "reaction_10778074": { "compartment": "compartment_7660", "id": "reaction_10778074", "reactome": "R-SCE-5625784", "name": "PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778057", "species_29358" ], "products": [ "species_113582", "species_10778071" ], "modifiers": [ [ "species_10778057", "catalyst" ] ], "additional_components": [ "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117" ] }, "reaction_10778123": { "compartment": "compartment_70101", "id": "reaction_10778123", "reactome": "R-SCE-5626507", "name": "IQGAPs bind F-actin, which is inhibited by calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778115", "species_10773881" ], "products": [ "species_10778119" ], "modifiers": [ [ "species_10778121", "inhibitor" ] ], "additional_components": [ "Q12280", "YPL242C", "species_29438", "P19073", "YLR229C", "P60010", "YFL039C", "species_113592", "P60010", "YFL039C", "Q12280", "YPL242C", "species_113592", "species_29438", "P19073", "YLR229C", "P06787", "YBR109C", "Q12280", "YPL242C", "species_74016", "species_29438", "P19073", "YLR229C" ] }, "reaction_10778078": { "compartment": "compartment_7660", "id": "reaction_10778078", "reactome": "R-SCE-5625796", "name": "Demethylase KDM4C binds KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778071", "species_10776769" ], "products": [ "species_10778076" ], "modifiers": [], "additional_components": [ "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "Q03833", "YDR096W", "P39956", "YER169W", "Q03833", "YDR096W", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P39956", "YER169W", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117" ] }, "reaction_10787831": { "compartment": "compartment_70101", "id": "reaction_10787831", "reactome": "R-SCE-8981931", "name": "RAC1 and CDC42 activate PAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768988", "species_10768894" ], "products": [ "species_10768986", "species_10778133" ], "modifiers": [], "additional_components": [ "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "P48562", "YNL298W", "Q03497", "YHL007C", "species_29438", "Q12469", "YOL113W", "P19073", "YLR229C" ] }, "reaction_10778020": { "compartment": "compartment_876", "id": "reaction_10778020", "reactome": "R-SCE-5623622", "name": "RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778012", "species_10769305" ], "products": [ "species_10778018" ], "modifiers": [], "additional_components": [ "YBL105C", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_29438" ] }, "reaction_10778160": { "compartment": "compartment_70101", "id": "reaction_10778160", "reactome": "R-SCE-5627775", "name": "Autophosphorylation of PAK1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10778137" ], "products": [ "species_29370", "species_10778157", "species_10768894" ], "modifiers": [ [ "species_10778137", "catalyst" ] ], "additional_components": [ "P48562", "YNL298W", "Q03497", "YHL007C", "species_29438", "Q12469", "YOL113W", "P19073", "YLR229C", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "Q03497", "YHL007C", "species_29438", "Q12469", "YOL113W", "P19073", "YLR229C" ] }, "reaction_10774032": { "compartment": "compartment_70101", "id": "reaction_10774032", "reactome": "R-SCE-2029456", "name": "RAC1 and CDC42 activate PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768972", "species_10768894" ], "products": [ "species_10768970", "species_10774023" ], "modifiers": [], "additional_components": [ "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C", "YHL007C", "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10787829": { "compartment": "compartment_70101", "id": "reaction_10787829", "reactome": "R-SCE-8981926", "name": "RAC1 and CDC42 activate PAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768992", "species_10768894" ], "products": [ "species_10768990", "species_10778135" ], "modifiers": [], "additional_components": [ "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C", "YHL007C", "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10778126": { "compartment": "compartment_876", "id": "reaction_10778126", "reactome": "R-SCE-5626549", "name": "IQGAPs bind CALM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778115", "species_10767596" ], "products": [ "species_10778121" ], "modifiers": [], "additional_components": [ "Q12280", "YPL242C", "species_29438", "P19073", "YLR229C", "P06787", "YBR109C", "species_74016", "P06787", "YBR109C", "Q12280", "YPL242C", "species_74016", "species_29438", "P19073", "YLR229C" ] }, "reaction_10788712": { "compartment": "compartment_70101", "id": "reaction_10788712", "reactome": "R-SCE-9626817", "name": "PKC phosphorylates NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10788701" ], "products": [ "species_10788710", "species_29370" ], "modifiers": [ [ "species_10777257", "catalyst" ] ], "additional_components": [ "P29366", "YBR200W", "P22696", "YJR017C", "P29366", "YBR200W", "P22696", "YJR017C", "YBL105C" ] }, "reaction_10774058": { "compartment": "compartment_70101", "id": "reaction_10774058", "reactome": "R-SCE-2029473", "name": "Branching and elongation of mother and daughter filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774056", "species_10767714" ], "products": [ "species_10773926" ], "modifiers": [], "additional_components": [ "P60010", "YFL039C", "P40518", "YIL062C", "P53731", "YNR035C", "species_29370", "species_113592", "P33204", "YKL013C", "P32381", "YDL029W", "P47117", "YJR065C", "P38328", "YBR234C", "Q05933", "YLR370C", "P60010", "YFL039C", "species_113592", "P40518", "YIL062C", "P60010", "YFL039C", "P53731", "YNR035C", "P33204", "YKL013C", "species_113592", "P32381", "YDL029W", "P47117", "YJR065C", "P38328", "YBR234C", "Q05933", "YLR370C" ] }, "reaction_10778036": { "compartment": "compartment_70101", "id": "reaction_10778036", "reactome": "R-SCE-5623667", "name": "PDPK1 phosphorylates PKN1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10778022" ], "products": [ "species_29370", "species_10764515", "species_10778027", "species_10769305" ], "modifiers": [ [ "species_10778022", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_179838", "species_29438", "Q12236", "YOL100W", "species_179838", "Q12236", "YOL100W", "YBL105C", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_179838", "species_29438", "Q12236", "YOL100W" ] }, "reaction_10782731": { "compartment": "compartment_1222693", "id": "reaction_10782731", "reactome": "R-SCE-6798174", "name": "PIK3C3:PIK3R4 phosphorylates PI to PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524165" ], "products": [ "species_29370", "species_1629751" ], "modifiers": [ [ "species_10782728", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W" ] }, "reaction_10778024": { "compartment": "compartment_876", "id": "reaction_10778024", "reactome": "R-SCE-5623632", "name": "RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764515", "species_10778018" ], "products": [ "species_10778022" ], "modifiers": [], "additional_components": [ "species_179838", "Q12236", "YOL100W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_179838", "species_29438", "Q12236", "YOL100W" ] }, "reaction_10767642": { "compartment": "compartment_70101", "id": "reaction_10767642", "reactome": "R-SCE-202127", "name": "eNOS synthesizes NO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29468", "species_29368" ], "products": [ "species_29366", "species_202124", "species_29968" ], "modifiers": [ [ "species_10767639", "catalyst" ], [ "species_5693375", "inhibitor" ] ], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "species_29870", "species_113596", "P11792", "YHR205W" ] }, "reaction_10777290": { "compartment": "compartment_876", "id": "reaction_10777290", "reactome": "R-SCE-5218821", "name": "PDK1 phosphorylates PKC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10765240" ], "products": [ "species_29370", "species_10777257" ], "modifiers": [ [ "species_10764513", "catalyst" ] ], "additional_components": [ "YBL105C", "YBL105C", "YOL100W" ] }, "reaction_10777285": { "compartment": "compartment_70101", "id": "reaction_10777285", "reactome": "R-SCE-5218813", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_112275", "species_10777268" ], "products": [ "species_10777283" ], "modifiers": [], "additional_components": [ "YBL105C", "species_112275", "P24583", "YBL105C", "species_74016" ] }, "reaction_10774274": { "compartment": "compartment_876", "id": "reaction_10774274", "reactome": "R-SCE-2317314", "name": "AKT binds PDPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767085", "species_10764515" ], "products": [ "species_10767087" ], "modifiers": [], "additional_components": [ "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "species_179838", "Q12236", "YOL100W", "P12688", "YKL126W", "species_179838", "Q12236", "YOL100W", "P11792", "YHR205W" ] }, "reaction_10777281": { "compartment": "compartment_70101", "id": "reaction_10777281", "reactome": "R-SCE-5218805", "name": "PKC autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10777257" ], "products": [ "species_29370", "species_10777268" ], "modifiers": [ [ "species_10777257", "catalyst" ] ], "additional_components": [ "YBL105C", "YBL105C", "YBL105C" ] }, "reaction_10767108": { "compartment": "compartment_70101", "id": "reaction_10767108", "reactome": "R-SCE-198270", "name": "PDPK1 phosphorylates AKT at T308", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10767087" ], "products": [ "species_29370", "species_10764515", "species_10767105" ], "modifiers": [ [ "species_10767087", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "species_179838", "Q12236", "YOL100W", "P11792", "YHR205W", "species_179838", "Q12236", "YOL100W", "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "Q12236", "YOL100W", "P11792", "YHR205W" ] }, "reaction_10766460": { "compartment": "compartment_70101", "id": "reaction_10766460", "reactome": "R-SCE-187688", "name": "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10766440" ], "products": [ "species_29370", "species_10766447" ], "modifiers": [ [ "species_10766457", "catalyst" ] ], "additional_components": [ "YKL171W", "YKL171W", "P32485", "YLR113W", "species_109496" ] }, "reaction_10767654": { "compartment": "compartment_70101", "id": "reaction_10767654", "reactome": "R-SCE-202137", "name": "AKT1 binds eNOS complex via HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767610", "species_10767095" ], "products": [ "species_10767618" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "P02829", "YPL240C", "species_74016", "species_73524", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "species_113596", "P12688", "YKL126W", "P11792", "YHR205W", "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_74016", "species_73524", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "P11792", "YHR205W", "species_113596" ] }, "reaction_10777296": { "compartment": "compartment_876", "id": "reaction_10777296", "reactome": "R-SCE-5218823", "name": "PKC phosphorylates sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10769088" ], "products": [ "species_29370", "species_10777293" ], "modifiers": [ [ "species_10777283", "catalyst" ] ], "additional_components": [ "YLR260W", "YLR260W", "species_112275", "P24583", "YBL105C", "species_74016" ] }, "reaction_10773346": { "compartment": "compartment_70101", "id": "reaction_10773346", "reactome": "R-SCE-1497784", "name": "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_10767635" ], "products": [ "species_10767639" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "species_29870", "P15108", "YMR186W", "species_113596", "P11792", "YHR205W", "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "species_29870", "species_113596", "P11792", "YHR205W" ] }, "reaction_10767637": { "compartment": "compartment_70101", "id": "reaction_10767637", "reactome": "R-SCE-202111", "name": "AKT1 phosphorylates eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767618", "species_113592" ], "products": [ "species_29370", "species_10767635" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_74016", "species_73524", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "P11792", "YHR205W", "species_113596", "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "species_29870", "P15108", "YMR186W", "species_113596", "P11792", "YHR205W" ] }, "reaction_10767219": { "compartment": "compartment_70101", "id": "reaction_10767219", "reactome": "R-SCE-198640", "name": "TORC2 (mTOR) phosphorylates AKT at S473", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767182", "species_113592" ], "products": [ "species_29370", "species_10767085" ], "modifiers": [ [ "species_10767216", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "Q08236", "YOL078W", "P32600", "YKL203C", "P41318", "YNL006W", "P40061", "YER093C", "P38346", "YBR270C", "P47041", "YJL058C" ] }, "reaction_10772766": { "compartment": "compartment_876", "id": "reaction_10772766", "reactome": "R-SCE-1299318", "name": "Activation of TASK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772763", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10766256": { "compartment": "compartment_70101", "id": "reaction_10766256", "reactome": "R-SCE-174124", "name": "Dephosphorylation of phospho-Cdh1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766246", "species_29356" ], "products": [ "species_10766234", "species_111294" ], "modifiers": [ [ "species_10766253", "catalyst" ] ], "additional_components": [ "YGL003C", "YGL003C", "Q00684", "YFR028C" ] }, "reaction_10769735": { "compartment": "compartment_7660", "id": "reaction_10769735", "reactome": "R-SCE-427514", "name": "eNoSC deacetylates histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769718", "species_427523" ], "products": [ "species_10768101", "species_427498", "species_427497" ], "modifiers": [ [ "species_10769732", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P06700", "YDL042C", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P38961", "YDR083W", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10769738": { "compartment": "compartment_7660", "id": "reaction_10769738", "reactome": "R-SCE-427527", "name": "eNoSC dimethylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768101", "species_77087" ], "products": [ "species_77502", "species_10763784" ], "modifiers": [ [ "species_10769732", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P06700", "YDL042C", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P38961", "YDR083W", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10765828": { "compartment": "compartment_5460", "id": "reaction_10765828", "reactome": "R-SCE-164840", "name": "ADP and Pi bind to ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_10765816" ], "products": [ "species_10765818" ], "modifiers": [], "additional_components": [ "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P30902", "YKL016C", "species_29370", "P21306", "YPL271W", "P38077", "YBR039W", "P07251", "ATP1", "P00854", "Q0085", "species_29372", "P00830", "ATP2", "P61829", "OLI1", "P05626", "YPL078C", "Q12165", "YDL004W", "P09457", "YDR298C", "Q12233", "YPR020W" ] }, "reaction_10765823": { "compartment": "compartment_5460", "id": "reaction_10765823", "reactome": "R-SCE-164832", "name": "ATPase synthesizes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765818" ], "products": [ "species_113521", "species_10765820" ], "modifiers": [ [ "species_10765818", "catalyst" ] ], "additional_components": [ "P24814", "YJR090C", "P30902", "YKL016C", "species_29370", "P21306", "YPL271W", "P38077", "YBR039W", "P07251", "ATP1", "P00854", "Q0085", "species_29372", "P00830", "ATP2", "P61829", "OLI1", "P05626", "YPL078C", "Q12165", "YDL004W", "P09457", "YDR298C", "Q12233", "YPR020W", "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "species_113592", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P30902", "YKL016C", "species_29370", "P21306", "YPL271W", "P38077", "YBR039W", "P07251", "ATP1", "P00854", "Q0085", "species_29372", "P00830", "ATP2", "P61829", "OLI1", "P05626", "YPL078C", "Q12165", "YDL004W", "P09457", "YDR298C", "Q12233", "YPR020W" ] }, "reaction_10765826": { "compartment": "compartment_5460", "id": "reaction_10765826", "reactome": "R-SCE-164834", "name": "Enzyme-bound ATP is released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163953", "species_10765820" ], "products": [ "species_113529", "species_113593", "species_10765816" ], "modifiers": [ [ "species_10765820", "catalyst" ] ], "additional_components": [ "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "species_113592", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "species_113592", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W" ] }, "reaction_10783791": { "compartment": "compartment_70101", "id": "reaction_10783791", "reactome": "R-SCE-6799545", "name": "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6799540", "species_29356" ], "products": [ "species_429579", "species_6799543" ], "modifiers": [ [ "species_10783788", "catalyst" ] ], "additional_components": [ "species_158417", "P22855", "YGL156W" ] }, "reaction_10765881": { "compartment": "compartment_70101", "id": "reaction_10765881", "reactome": "R-SCE-165766", "name": "Phosphorylation and activation of eIF4G by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762672", "species_113592" ], "products": [ "species_29370", "species_10765879" ], "modifiers": [ [ "species_10765848", "catalyst" ] ], "additional_components": [ "P39936", "YGL049C", "P39935", "YGR162W", "P39936", "YGL049C", "P39935", "YGR162W", "YBR028C" ] }, "reaction_10765867": { "compartment": "compartment_70101", "id": "reaction_10765867", "reactome": "R-SCE-165726", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10762517" ], "products": [ "species_29370", "species_10765864" ], "modifiers": [ [ "species_10765848", "catalyst" ] ], "additional_components": [ "P0CX37", "RPS6A", "P0CX38", "RPS6B", "P0CX37", "RPS6A", "P0CX38", "RPS6B", "YBR028C" ] }, "reaction_10789075": { "compartment": "compartment_70101", "id": "reaction_10789075", "reactome": "R-SCE-9679044", "name": "FKBP1A binds sirolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678687", "species_10789071" ], "products": [ "species_10789073" ], "modifiers": [], "additional_components": [ "YNL135C", "species_9678687", "P20081", "YNL135C" ] }, "reaction_10770295": { "compartment": "compartment_876", "id": "reaction_10770295", "reactome": "R-SCE-445714", "name": "Aquaporin-3 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10770292", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10789035": { "compartment": "compartment_70101", "id": "reaction_10789035", "reactome": "R-SCE-9668389", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789031", "species_10771525" ], "products": [ "species_10789033" ], "modifiers": [], "additional_components": [ "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "P39955", "YER047C", "Q04272", "YMR077C", "P53843", "YNL265C", "YPR173C", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P52917", "YPR173C", "P36108", "YKL002W", "P39955", "YER047C", "Q04272", "YMR077C", "P53843", "YNL265C" ] }, "reaction_10789037": { "compartment": "compartment_70101", "id": "reaction_10789037", "reactome": "R-SCE-9668405", "name": "SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789019", "species_10789029" ], "products": [ "species_10789031" ], "modifiers": [], "additional_components": [ "YER047C", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "Q04272", "YMR077C", "P53843", "YNL265C", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "P39955", "YER047C", "Q04272", "YMR077C", "P53843", "YNL265C" ] }, "reaction_10789040": { "compartment": "compartment_70101", "id": "reaction_10789040", "reactome": "R-SCE-9668419", "name": "SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768744", "species_113592", "species_29356" ], "products": [ "species_29370", "species_10768740", "species_29372" ], "modifiers": [ [ "species_10789031", "catalyst" ] ], "additional_components": [ "species_29420", "P09734", "YML124C", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "species_29420", "P09734", "YML124C", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "P39955", "YER047C", "Q04272", "YMR077C", "P53843", "YNL265C" ] }, "reaction_10786014": { "compartment": "compartment_876", "id": "reaction_10786014", "reactome": "R-SCE-8855130", "name": "VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786004" ], "products": [ "species_10786012" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "P09232", "YEL060C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P09232", "YEL060C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C" ] }, "reaction_10781954": { "compartment": "compartment_1660541", "id": "reaction_10781954", "reactome": "R-SCE-6784738", "name": "Degradation of PCSK9:LDLR:Clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781950" ], "products": [ "species_10781948" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "P09232", "YEL060C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C" ] }, "reaction_10785158": { "compartment": "compartment_70101", "id": "reaction_10785158", "reactome": "R-SCE-6813720", "name": "NCEH1 hydrolyzes cholesterol esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163579", "species_29356" ], "products": [ "species_216762", "species_8876730" ], "modifiers": [ [ "species_10785155", "catalyst" ] ], "additional_components": [ "YGR263C" ] }, "reaction_10768163": { "compartment": "compartment_984", "id": "reaction_10768163", "reactome": "R-SCE-264695", "name": "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194276", "species_171149" ], "products": [ "species_194236", "species_171076" ], "modifiers": [ [ "species_10768160", "catalyst" ] ], "additional_components": [ "P47139", "YJR098C", "P54857", "YDR058C" ] }, "reaction_10786892": { "compartment": "compartment_12045", "id": "reaction_10786892", "reactome": "R-SCE-8876485", "name": "CHOL translocates from lysosome membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786890" ], "products": [ "species_193384", "species_10786888" ], "modifiers": [], "additional_components": [ "Q12200", "YPL006W", "species_171095", "YPL006W" ] }, "reaction_10781952": { "compartment": "compartment_1660541", "id": "reaction_10781952", "reactome": "R-SCE-6784729", "name": "PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781918" ], "products": [ "species_10781950" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P09232", "YEL060C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P36000", "YKL135C", "P09232", "YEL060C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C" ] }, "reaction_10785516": { "compartment": "compartment_70101", "id": "reaction_10785516", "reactome": "R-SCE-8850945", "name": "Casein kinase II phosphorylates PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767316", "species_113592" ], "products": [ "species_29370", "species_10785514" ], "modifiers": [ [ "species_10774577", "catalyst" ] ], "additional_components": [ "YNL128W", "YNL128W", "P15790", "CKA1", "P38930", "CKB2", "P19454", "CKA2" ] }, "reaction_10787467": { "compartment": "compartment_70101", "id": "reaction_10787467", "reactome": "R-SCE-8948800", "name": "TNKS and TNKS2 PARylate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767316", "species_29360" ], "products": [ "species_10787457", "species_197277" ], "modifiers": [ [ "species_10787462", "catalyst" ] ], "additional_components": [ "YNL128W", "YNL128W", "YGR232W" ] }, "reaction_10784359": { "compartment": "compartment_70101", "id": "reaction_10784359", "reactome": "R-SCE-6807206", "name": "USP13 and OTUD3 deubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784356", "species_29356" ], "products": [ "species_10767316", "species_10760634" ], "modifiers": [ [ "species_10781697", "catalyst" ] ], "additional_components": [ "YNL128W", "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YBR058C" ] }, "reaction_10784353": { "compartment": "compartment_70101", "id": "reaction_10784353", "reactome": "R-SCE-6807134", "name": "NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767316", "species_10760634" ], "products": [ "species_10784348" ], "modifiers": [ [ "species_10772117", "catalyst" ] ], "additional_components": [ "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YNL128W", "YER125W" ] }, "reaction_10785528": { "compartment": "compartment_70101", "id": "reaction_10785528", "reactome": "R-SCE-8850992", "name": "Proteasome degrades polyubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785526" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P53916", "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10784088": { "compartment": "compartment_876", "id": "reaction_10784088", "reactome": "R-SCE-6801101", "name": "RABGGTA binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784079", "species_10784084" ], "products": [ "species_10784086" ], "modifiers": [], "additional_components": [ "YJL031C", "YPR176C", "P20133", "YPR176C", "Q00618", "YJL031C" ] }, "reaction_10784074": { "compartment": "compartment_70101", "id": "reaction_10784074", "reactome": "R-SCE-6800793", "name": "PIDD1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784068" ], "products": [ "species_10784072" ], "modifiers": [], "additional_components": [ "YJL005W", "YJL005W" ] }, "reaction_10784097": { "compartment": "compartment_70101", "id": "reaction_10784097", "reactome": "R-SCE-6801109", "name": "CHM binds RGGT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784093", "species_10784086" ], "products": [ "species_10784095" ], "modifiers": [], "additional_components": [ "YOR370C", "P20133", "YPR176C", "Q00618", "YJL031C", "P32864", "YOR370C", "P20133", "YPR176C", "Q00618", "YJL031C" ] }, "reaction_10784124": { "compartment": "compartment_17927", "id": "reaction_10784124", "reactome": "R-SCE-6801242", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784120", "species_10784101" ], "products": [ "species_10784122" ], "modifiers": [], "additional_components": [ "P35200", "YLR168C", "Q05776", "YLR193C", "Q04006", "YDR185C", "P35200", "YLR168C", "Q05776", "YLR193C", "Q04006", "YDR185C", "O60200", "MDM35" ] }, "reaction_10784070": { "compartment": "compartment_7660", "id": "reaction_10784070", "reactome": "R-SCE-6800490", "name": "ATM phosphorylates PIDD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10784065" ], "products": [ "species_113582", "species_10784068" ], "modifiers": [ [ "species_10768327", "catalyst" ] ], "additional_components": [ "YJL005W", "YJL005W", "YBL088C" ] }, "reaction_10784127": { "compartment": "compartment_17906", "id": "reaction_10784127", "reactome": "R-SCE-6801250", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590" ], "products": [ "species_1524101" ], "modifiers": [ [ "species_10784122", "catalyst" ] ], "additional_components": [ "P35200", "YLR168C", "Q05776", "YLR193C", "Q04006", "YDR185C", "O60200", "MDM35" ] }, "reaction_10788980": { "compartment": "compartment_70101", "id": "reaction_10788980", "reactome": "R-SCE-9661405", "name": "ABCC1 transports BIL from cytosol to extracellular region (blood)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189386" ], "products": [ "species_9661418" ], "modifiers": [ [ "species_10768249", "catalyst" ] ], "additional_components": [ "YDR135C" ] }, "reaction_10779396": { "compartment": "compartment_7660", "id": "reaction_10779396", "reactome": "R-SCE-5683792", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779391" ], "products": [ "species_113582", "species_10761098" ], "modifiers": [ [ "species_10779391", "catalyst" ] ], "additional_components": [ "P39009", "YDL101C", "YDL101C", "P39009", "YDL101C" ] }, "reaction_10766387": { "compartment": "compartment_7660", "id": "reaction_10766387", "reactome": "R-SCE-176264", "name": "Recruitment of the Rad9-Hus1-Rad1 complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766382", "species_10766378" ], "products": [ "species_10766384" ], "modifiers": [ [ "species_10766382", "catalyst" ] ], "additional_components": [ "P22336", "YAR007C", "P32641", "YER173W", "P40348", "YJR068W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "Q02574", "YLR288C", "Q08949", "YPL194W", "P48581", "YOR368W", "Q02574", "YLR288C", "P22336", "YAR007C", "Q08949", "YPL194W", "P32641", "YER173W", "P40348", "YJR068W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P48581", "YOR368W", "P38629", "YNL290W", "P22336", "YAR007C", "P32641", "YER173W", "P40348", "YJR068W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W" ] }, "reaction_10787270": { "compartment": "compartment_70101", "id": "reaction_10787270", "reactome": "R-SCE-8941895", "name": "Formation of CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787266", "species_10787216" ], "products": [ "species_10787268" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P00546", "YBR160W", "P36005", "YKL161C", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760833": { "compartment": "compartment_7660", "id": "reaction_10760833", "reactome": "R-SCE-68950", "name": "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10760281", "species_30187", "species_29604", "species_29892" ], "products": [ "species_10760830" ], "modifiers": [ [ "species_10760246", "catalyst" ] ], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W" ] }, "reaction_10785898": { "compartment": "compartment_70101", "id": "reaction_10785898", "reactome": "R-SCE-8853496", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785889", "species_10785894" ], "products": [ "species_10785896" ], "modifiers": [], "additional_components": [ "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "YPL209C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C" ] }, "reaction_10763956": { "compartment": "compartment_7660", "id": "reaction_10763956", "reactome": "R-SCE-75809", "name": "Phosphorylation of Cdc25C at Ser216 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763791", "species_29358" ], "products": [ "species_10763794", "species_113582" ], "modifiers": [ [ "species_10761098", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "YDL101C" ] }, "reaction_10774551": { "compartment": "compartment_70101", "id": "reaction_10774551", "reactome": "R-SCE-2529015", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774539", "species_29356" ], "products": [ "species_10774549", "species_29372" ], "modifiers": [ [ "species_2529006", "catalyst" ] ], "additional_components": [ "P38170", "YBL097W", "P38989", "YFR031C", "Q12267", "YLR086W", "Q06156", "YLR272C", "Q06680", "YDR325W", "P38170", "YBL097W", "P38989", "YFR031C", "Q12267", "YLR086W", "Q06156", "YLR272C", "Q06680", "YDR325W" ] }, "reaction_10784202": { "compartment": "compartment_7660", "id": "reaction_10784202", "reactome": "R-SCE-6804724", "name": "MDM2 ubiquitinates phosphorylated MDM4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768310", "species_10760537" ], "products": [ "species_10784199" ], "modifiers": [ [ "species_10768310", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W" ] }, "reaction_10774378": { "compartment": "compartment_1598585", "id": "reaction_10774378", "reactome": "R-SCE-2466068", "name": "Phosphorylation of cohesin by PLK1 at chromosomal arms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10774363" ], "products": [ "species_10774375", "species_29370" ], "modifiers": [ [ "species_10768675", "catalyst" ] ], "additional_components": [ "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "YMR001C" ] }, "reaction_10788671": { "compartment": "compartment_13231", "id": "reaction_10788671", "reactome": "R-SCE-9624798", "name": "LBR binds KPNB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788667", "species_10768074" ], "products": [ "species_10788669" ], "modifiers": [], "additional_components": [ "YNL280C", "YLR347C", "Q06142", "YLR347C", "P32462", "YNL280C" ] }, "reaction_10763796": { "compartment": "compartment_7660", "id": "reaction_10763796", "reactome": "R-SCE-75010", "name": "Phosphorylation of Cdc25C at Ser 216 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763791", "species_29358" ], "products": [ "species_10763794", "species_113582" ], "modifiers": [ [ "species_10761086", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "P36002", "YKL198C", "P47116", "YJR059W", "P06782", "YDR477W" ] }, "reaction_10774466": { "compartment": "compartment_7660", "id": "reaction_10774466", "reactome": "R-SCE-2473152", "name": "Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10774462" ], "products": [ "species_2485002", "species_10774464" ], "modifiers": [ [ "species_10774449", "catalyst" ] ], "additional_components": [ "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "YFR027W" ] }, "reaction_10766462": { "compartment": "compartment_7660", "id": "reaction_10766462", "reactome": "R-SCE-187948", "name": "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10766260" ], "products": [ "species_113582", "species_10766262" ], "modifiers": [ [ "species_10760454", "catalyst" ] ], "additional_components": [ "YGL003C", "YGL003C", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10787375": { "compartment": "compartment_7660", "id": "reaction_10787375", "reactome": "R-SCE-8942836", "name": "CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10787337" ], "products": [ "species_113582", "species_10787373" ], "modifiers": [ [ "species_10763257", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "Q03290", "YDR460W", "P37366", "YPR025C", "P06242", "YDL108W" ] }, "reaction_10788685": { "compartment": "compartment_70101", "id": "reaction_10788685", "reactome": "R-SCE-9624876", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788673", "species_9624879" ], "products": [ "species_10788683" ], "modifiers": [], "additional_components": [ "P32835", "YLR293C", "species_29438", "P32835", "YLR293C", "species_29438" ] }, "reaction_10764018": { "compartment": "compartment_13231", "id": "reaction_10764018", "reactome": "R-SCE-75823", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763979" ], "products": [ "species_10764006" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10766207": { "compartment": "compartment_13231", "id": "reaction_10766207", "reactome": "R-SCE-170159", "name": "Translocation of Cdc25 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766203" ], "products": [ "species_10766205" ], "modifiers": [], "additional_components": [ "P23748", "YMR036C", "P23748", "YMR036C" ] }, "reaction_10788374": { "compartment": "compartment_70101", "id": "reaction_10788374", "reactome": "R-SCE-9029987", "name": "p-S216-CDC25C translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763794" ], "products": [ "species_10763798" ], "modifiers": [], "additional_components": [ "YMR036C", "YMR036C" ] }, "reaction_10760284": { "compartment": "compartment_7660", "id": "reaction_10760284", "reactome": "R-SCE-68913", "name": "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10760279" ], "products": [ "species_10760281", "species_10760275" ], "modifiers": [ [ "species_10760279", "catalyst" ] ], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P20457", "YKL045W" ] }, "reaction_10774945": { "compartment": "compartment_70101", "id": "reaction_10774945", "reactome": "R-SCE-3002798", "name": "Cytosolic PLK1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765349" ], "products": [ "species_10765474" ], "modifiers": [], "additional_components": [ "YMR001C", "YMR001C" ] }, "reaction_10766199": { "compartment": "compartment_13231", "id": "reaction_10766199", "reactome": "R-SCE-170149", "name": "Translocation of active Cdc25C to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765343" ], "products": [ "species_10766197" ], "modifiers": [], "additional_components": [ "YMR036C", "YMR036C" ] }, "reaction_10789351": { "compartment": "compartment_7660", "id": "reaction_10789351", "reactome": "R-SCE-9754129", "name": "CDK6 inhibitors bind CDK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9754132", "species_10787355" ], "products": [ "species_10789349" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=10426", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=7379", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "P24868", "YGR108W", "P00546", "YBR160W", "P36005", "YKL161C", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10426", "P20438", "YPL256C", "P32943", "YGR109C", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "LigandDisplayForward?ligandId=7934" ] }, "reaction_10788688": { "compartment": "compartment_70101", "id": "reaction_10788688", "reactome": "R-SCE-9624893", "name": "RAN stimulates fusion of nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788683", "species_29356" ], "products": [ "species_10767791", "species_29372", "species_9624890" ], "modifiers": [ [ "species_10774940", "catalyst" ] ], "additional_components": [ "P32835", "YLR293C", "species_29438", "species_29420", "P32835", "YLR293C", "P11745", "YMR235C", "Q12306", "YDR510W" ] }, "reaction_10789361": { "compartment": "compartment_7660", "id": "reaction_10789361", "reactome": "R-SCE-9754130", "name": "CDK4 inhibitors bind CDK4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787371", "species_9754127" ], "products": [ "species_10789359" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "LigandDisplayForward?ligandId=7938", "LigandDisplayForward?ligandId=5950", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=10426", "LigandDisplayForward?ligandId=5707", "LigandDisplayForward?ligandId=7744", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "pubchem.compound:9933545", "LigandDisplayForward?ligandId=8203", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=5680", "LigandDisplayForward?ligandId=7938", "P13365", "YAL040C", "LigandDisplayForward?ligandId=11189", "P24868", "YGR108W", "P00546", "YBR160W", "P36005", "YKL161C", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5707", "LigandDisplayForward?ligandId=7383", "P24869", "YPR119W", "pubchem.compound:9933545", "LigandDisplayForward?ligandId=8203", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=5950", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=10426", "P20438", "YPL256C", "P32943", "YGR109C", "LigandDisplayForward?ligandId=7744", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7382", "P30283", "YPR120C", "P20437", "YMR199W", "LigandDisplayForward?ligandId=5680" ] }, "reaction_10774454": { "compartment": "compartment_7660", "id": "reaction_10774454", "reactome": "R-SCE-2468039", "name": "Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774436", "species_113560" ], "products": [ "species_2485002", "species_10774444" ], "modifiers": [ [ "species_10774449", "catalyst" ] ], "additional_components": [ "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "YFR027W" ] }, "reaction_10774580": { "compartment": "compartment_70101", "id": "reaction_10774580", "reactome": "R-SCE-2529020", "name": "CK2 phosphorylates condensin I subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774549", "species_113592" ], "products": [ "species_29370", "species_10774539" ], "modifiers": [ [ "species_10774577", "catalyst" ] ], "additional_components": [ "P38170", "YBL097W", "P38989", "YFR031C", "Q12267", "YLR086W", "Q06156", "YLR272C", "Q06680", "YDR325W", "P38170", "YBL097W", "P38989", "YFR031C", "Q12267", "YLR086W", "Q06156", "YLR272C", "Q06680", "YDR325W", "P15790", "CKA1", "P38930", "CKB2", "P19454", "CKA2" ] }, "reaction_10766243": { "compartment": "compartment_7660", "id": "reaction_10766243", "reactome": "R-SCE-174110", "name": "Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10766239" ], "products": [ "species_10766241", "species_113550" ], "modifiers": [ [ "species_10761051", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "YMR036C" ] }, "reaction_10774394": { "compartment": "compartment_70101", "id": "reaction_10774394", "reactome": "R-SCE-2467775", "name": "Autocleavage of ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774383" ], "products": [ "species_10774391" ], "modifiers": [ [ "species_10774383", "catalyst" ] ], "additional_components": [ "YGR098C", "Q03018", "YGR098C", "YGR098C" ] }, "reaction_10765338": { "compartment": "compartment_70101", "id": "reaction_10765338", "reactome": "R-SCE-141437", "name": "Formation of the MCC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765330", "species_10765320", "species_10765315", "species_10765325" ], "products": [ "species_10765332" ], "modifiers": [], "additional_components": [ "YJL030W", "YOR026W", "P47074", "YJL013C", "P41695", "YGR188C", "YGL116W", "P47074", "YJL013C", "P40958", "YJL030W", "P41695", "YGR188C", "P26309", "YGL116W", "P26449", "YOR026W" ] }, "reaction_10765336": { "compartment": "compartment_70101", "id": "reaction_10765336", "reactome": "R-SCE-141429", "name": "Inactivation of APC/C via CDC20 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765330", "species_10765325" ], "products": [ "species_10765334" ], "modifiers": [], "additional_components": [ "YJL030W", "YGL116W", "P40958", "YJL030W", "P26309", "YGL116W" ] }, "reaction_10774266": { "compartment": "compartment_20699", "id": "reaction_10774266", "reactome": "R-SCE-2214351", "name": "PLK1 phosphorylates GORASP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774258", "species_113592" ], "products": [ "species_10774263", "species_29370" ], "modifiers": [ [ "species_10774258", "catalyst" ] ], "additional_components": [ "P01123", "YFL038C", "P32562", "YMR001C", "species_29438", "Q04410", "YDR517W", "P01123", "YFL038C", "P32562", "YMR001C", "species_29438", "Q04410", "YDR517W", "P01123", "YFL038C", "P32562", "YMR001C", "species_29438", "Q04410", "YDR517W" ] }, "reaction_10784232": { "compartment": "compartment_7660", "id": "reaction_10784232", "reactome": "R-SCE-6804955", "name": "ATM phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10768288" ], "products": [ "species_113582", "species_10784230" ], "modifiers": [ [ "species_10768327", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "YBL088C" ] }, "reaction_10766264": { "compartment": "compartment_13231", "id": "reaction_10766264", "reactome": "R-SCE-174273", "name": "Translocation of Cyclin A:Cdk2 complexes to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766227" ], "products": [ "species_10766241" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10768330": { "compartment": "compartment_7660", "id": "reaction_10768330", "reactome": "R-SCE-349455", "name": "Phosphorylation of MDM4 by ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10768320" ], "products": [ "species_113582", "species_10768298" ], "modifiers": [ [ "species_10768327", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "YBL088C" ] }, "reaction_10777308": { "compartment": "compartment_13231", "id": "reaction_10777308", "reactome": "R-SCE-5221130", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_5221122" ], "products": [ "species_113550", "species_5221124" ], "modifiers": [ [ "species_10776501", "catalyst" ] ], "additional_components": [ "YMR165C" ] }, "reaction_10768312": { "compartment": "compartment_7660", "id": "reaction_10768312", "reactome": "R-SCE-349426", "name": "Phosphorylation of MDM4 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10768298" ], "products": [ "species_113582", "species_10768310" ], "modifiers": [ [ "species_10761098", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "YDL101C" ] }, "reaction_10764016": { "compartment": "compartment_13231", "id": "reaction_10764016", "reactome": "R-SCE-75822", "name": "Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763990" ], "products": [ "species_10764014" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10766229": { "compartment": "compartment_70101", "id": "reaction_10766229", "reactome": "R-SCE-174054", "name": "Formation of Cyclin A:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760999", "species_10766189" ], "products": [ "species_10766227" ], "modifiers": [], "additional_components": [ "YBR160W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10774943": { "compartment": "compartment_13231", "id": "reaction_10774943", "reactome": "R-SCE-3000449", "name": "UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774930", "species_10774813" ], "products": [ "species_10774805", "species_10774940" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P11745", "YMR235C", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "P11745", "YMR235C", "Q12306", "YDR510W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10787339": { "compartment": "compartment_13231", "id": "reaction_10787339", "reactome": "R-SCE-8942803", "name": "Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787303" ], "products": [ "species_10787337" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10788681": { "compartment": "compartment_1598585", "id": "reaction_10788681", "reactome": "R-SCE-9624845", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10767791" ], "products": [ "species_10788673", "species_29420" ], "modifiers": [ [ "species_10788678", "catalyst" ] ], "additional_components": [ "species_29420", "P32835", "YLR293C", "P32835", "YLR293C", "species_29438", "YGL097W" ] }, "reaction_10766195": { "compartment": "compartment_13231", "id": "reaction_10766195", "reactome": "R-SCE-170120", "name": "Translocation of Cdc25B to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766191" ], "products": [ "species_10766193" ], "modifiers": [], "additional_components": [ "YMR036C", "YMR036C" ] }, "reaction_10766465": { "compartment": "compartment_7660", "id": "reaction_10766465", "reactome": "R-SCE-187949", "name": "CAK-mediated phosphorylation of Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766241", "species_29358" ], "products": [ "species_113582", "species_10760454" ], "modifiers": [ [ "species_10763257", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03290", "YDR460W", "P37366", "YPR025C", "P06242", "YDL108W" ] }, "reaction_10779393": { "compartment": "compartment_7660", "id": "reaction_10779393", "reactome": "R-SCE-5683774", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779389" ], "products": [ "species_10779391" ], "modifiers": [], "additional_components": [ "YDL101C", "P39009", "YDL101C" ] }, "reaction_10784210": { "compartment": "compartment_7660", "id": "reaction_10784210", "reactome": "R-SCE-6804741", "name": "MDM2 forms homo- or heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768288", "species_10784204" ], "products": [ "species_10784208" ], "modifiers": [ [ "species_10768327", "inhibitor" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "YBL088C" ] }, "reaction_10785940": { "compartment": "compartment_70101", "id": "reaction_10785940", "reactome": "R-SCE-8854041", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760634", "species_10785896" ], "products": [ "species_10785937" ], "modifiers": [ [ "species_10785896", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C" ] }, "reaction_10764022": { "compartment": "compartment_70101", "id": "reaction_10764022", "reactome": "R-SCE-75825", "name": "Proteasome mediated degradation of Cyclin D1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764020" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P05759", "RPS31", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P30283", "YPR120C", "P20437", "YMR199W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10785942": { "compartment": "compartment_70101", "id": "reaction_10785942", "reactome": "R-SCE-8854044", "name": "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785937" ], "products": [ "species_10785889", "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10772729": { "compartment": "compartment_876", "id": "reaction_10772729", "reactome": "R-SCE-1296348", "name": "Activation of TWIK-related K+ channel (TREK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772726", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10766923": { "compartment": "compartment_70101", "id": "reaction_10766923", "reactome": "R-SCE-195664", "name": "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_29368", "species_195691" ], "products": [ "species_29366", "species_195655", "species_29356" ], "modifiers": [ [ "species_10766920", "catalyst" ] ], "additional_components": [ "YLR056W" ] }, "reaction_10764912": { "compartment": "compartment_12045", "id": "reaction_10764912", "reactome": "R-SCE-111883", "name": "Hydrolysis of phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_140356", "species_428981" ], "modifiers": [ [ "species_10764907", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C", "species_429802" ] }, "reaction_10764967": { "compartment": "compartment_70101", "id": "reaction_10764967", "reactome": "R-SCE-112037", "name": "Inactivation of PLC beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764872", "species_29356" ], "products": [ "species_29372", "species_10764856", "species_10764965" ], "modifiers": [], "additional_components": [ "P32383", "YPL268W", "species_29438", "P10823", "YER020W", "YPL268W", "species_29420", "P10823", "YER020W" ] }, "reaction_10764909": { "compartment": "compartment_70101", "id": "reaction_10764909", "reactome": "R-SCE-111881", "name": "Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_74016", "species_10764905" ], "products": [ "species_10764907" ], "modifiers": [], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C", "species_429802" ] }, "reaction_10764875": { "compartment": "compartment_70101", "id": "reaction_10764875", "reactome": "R-SCE-111879", "name": "PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10764872", "catalyst" ] ], "additional_components": [ "P32383", "YPL268W", "species_29438", "P10823", "YER020W" ] }, "reaction_10764925": { "compartment": "compartment_70101", "id": "reaction_10764925", "reactome": "R-SCE-111898", "name": "Phosphorylation of cPLA2 by ERK-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10764922" ], "products": [ "species_29370", "species_10764905" ], "modifiers": [ [ "species_10764614", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "YBL016W" ] }, "reaction_10779083": { "compartment": "compartment_70101", "id": "reaction_10779083", "reactome": "R-SCE-5679041", "name": "ABCC2 transports BMG,BDG from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_5679042", "species_29356" ], "products": [ "species_29370", "species_5679034", "species_29372" ], "modifiers": [ [ "species_10772886", "catalyst" ] ], "additional_components": [ "species_159160", "species_159149", "species_159160", "species_159149", "P14772", "YLL015W", "P39109", "YDR135C", "P32386", "YLL048C", "P38735", "YHL035C" ] }, "reaction_10774756": { "compartment": "compartment_7660", "id": "reaction_10774756", "reactome": "R-SCE-2990833", "name": "Conjugation of SUMO1 to UBA2:SAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10774743", "species_10774738" ], "products": [ "species_10774753", "species_164121", "species_113541" ], "modifiers": [ [ "species_10774738", "catalyst" ] ], "additional_components": [ "YDR510W", "P52488", "YDR390C", "Q06624", "YPR180W", "P52488", "YDR390C", "Q06624", "YPR180W", "Q12306", "YDR510W", "P52488", "YDR390C", "Q06624", "YPR180W" ] }, "reaction_10774681": { "compartment": "compartment_70101", "id": "reaction_10774681", "reactome": "R-SCE-2730835", "name": "Autophosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767671", "species_113592" ], "products": [ "species_29370", "species_10774679" ], "modifiers": [], "additional_components": [ "species_112275", "P24583", "YBL105C", "species_112275", "P24583", "YBL105C" ] }, "reaction_10766028": { "compartment": "compartment_70101", "id": "reaction_10766028", "reactome": "R-SCE-168162", "name": "Phosphorylation of human JNKs by activated MKK4/MKK7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10765968" ], "products": [ "species_29370", "species_10765974" ], "modifiers": [ [ "species_10766025", "catalyst" ] ], "additional_components": [ "YPR054W", "YPR054W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10770904": { "compartment": "compartment_70101", "id": "reaction_10770904", "reactome": "R-SCE-451418", "name": "Pellino ubiquitinates IRAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770887" ], "products": [ "species_10770901" ], "modifiers": [ [ "species_10770887", "catalyst" ] ], "additional_components": [ "P43633", "YGL021W", "P32789", "YBL009W", "P05759", "RPS31", "P53152", "MMS2", "P52490", "UBC13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P43633", "YGL021W", "P32789", "YBL009W", "P53152", "MMS2", "P52490", "UBC13", "P43633", "YGL021W", "P32789", "YBL009W", "P05759", "RPS31", "P53152", "MMS2", "P52490", "UBC13", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10789090": { "compartment": "compartment_70101", "id": "reaction_10789090", "reactome": "R-SCE-9690461", "name": "FKBP1A binds tacrolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678991", "species_10789071" ], "products": [ "species_10789088" ], "modifiers": [], "additional_components": [ "YNL135C", "P20081", "YNL135C", "species_9678991" ] }, "reaction_10769144": { "compartment": "compartment_70101", "id": "reaction_10769144", "reactome": "R-SCE-392530", "name": "p-S400-Cot phosphorylates NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769138", "species_113592" ], "products": [ "species_29370", "species_10769141" ], "modifiers": [ [ "species_10768963", "catalyst" ] ], "additional_components": [ "YCR073C", "YCR073C", "P25390", "YCR073C", "P53599", "YNR031C" ] }, "reaction_10767769": { "compartment": "compartment_7660", "id": "reaction_10767769", "reactome": "R-SCE-203797", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10767354" ], "products": [ "species_10767374", "species_113550" ], "modifiers": [ [ "species_10767766", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "P41808", "YPR054W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P41808", "YPR054W", "Q00772", "YHR030C", "P14681", "YGR040W", "P40479", "YIL113W", "P38590", "YNL053W" ] }, "reaction_10772408": { "compartment": "compartment_70101", "id": "reaction_10772408", "reactome": "R-SCE-983156", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772358", "species_113592", "species_10772364" ], "products": [ "species_10772379", "species_111294", "species_10772356", "species_76577" ], "modifiers": [ [ "species_10772364", "catalyst" ] ], "additional_components": [ "P22515", "YKL210W", "P15732", "YDR059C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P05759", "RPS31", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52491", "YLR306W", "P21734", "YDR177W", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P32943", "YGR109C", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P22515", "YKL210W", "P15732", "YDR059C", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P52491", "YLR306W", "P21734", "YDR177W", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P32943", "YGR109C", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C" ] }, "reaction_10783476": { "compartment": "compartment_1462052", "id": "reaction_10783476", "reactome": "R-SCE-6798748", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783290" ], "products": [ "species_10783474" ], "modifiers": [], "additional_components": [ "Q06625", "YPR184W", "P32807", "YMR284W", "P25043", "YOR157C", "P06738", "YPR160W", "P02994", "YBR118W", "P47103", "YJR032W", "P04806", "YFR053C", "Q12096", "YOR320C", "Q04437", "YMR106C", "Q03262", "YMR278W", "P38764", "YHR027C", "P17121", "YDR389W", "Q04120", "YDR453C", "P52489", "YOR347C", "Q08723", "YOR261C", "P38930", "CKB2", "P12709", "YBR196C", "P36010", "YKL067W", "P34760", "YML028W", "P32485", "YLR113W", "P32379", "YGR253C", "P38696", "YHR129C", "P16862", "YMR205C", "P40361", "YJL070C", "P25694", "YDL126C", "P15202", "YDR256C", "P46958", "YJL146W", "P47011", "YJL137C", "Q06103", "YPR108W", "P21954", "YDL066W", "P16861", "YGR240C", "P17709", "YCL040W", "P23724", "YBL041W", "P50094", "YML056C", "P15274", "YML035C", "P33297", "YOR117W", "Q06204", "YLR446W", "Q03280", "YDR457W", "P38985", "YDL092W", "Q12377", "YDL097C", "P10592", "YLL024C", "P47079", "YJL008C", "P32873", "YPL115C", "P11633", "YBR089C-A", "P39960", "YER155C", "P32769", "YKR084C", "Q06549", "YLR245C", "P15891", "YCR088W", "Q12250", "YDL147W", "P04807", "YGL253W", "P00549", "YAL038W", "P50095", "YLR432W", "Q08491", "SKI7", "P23639", "YML092C", "Q12156", "YDR063W", "P39083", "YOR127W", "P53691", "YLR216C", "P32324", "EFT2", "P38697", "YHR216W", "P49435", "YML022W", "P02829", "YPL240C", "P38339", "YBR260C", "P39958", "YER136W", "P05373", "YGL040C", "Q05788", "YLR209C", "P06634", "YOR204W", "P38862", "YHR171W", "P40518", "YIL062C", "Q04409", "YDR516C", "P38150", "YJL070C", "Q06407", "YDR379W", "Q04062", "YDR427W", "P33299", "YKL145W", "P32464", "YKL189W", "P40016", "YER021W", "P15108", "YMR186W", "P39988", "YEL029C", "P43588", "YFR004W", "P36143", "YKR058W", "Q06625", "YPR184W", "P32807", "YMR284W", "P25043", "YOR157C", "P06738", "YPR160W", "P02994", "YBR118W", "P47103", "YJR032W", "P04806", "YFR053C", "Q12096", "YOR320C", "Q04437", "YMR106C", "Q03262", "YMR278W", "P38764", "YHR027C", "P17121", "YDR389W", "Q04120", "YDR453C", "P52489", "YOR347C", "Q08723", "YOR261C", "P38930", "CKB2", "P12709", "YBR196C", "P36010", "YKL067W", "P34760", "YML028W", "P32485", "YLR113W", "P32379", "YGR253C", "P38696", "YHR129C", "P16862", "YMR205C", "P40361", "YJL070C", "P25694", "YDL126C", "P15202", "YDR256C", "P46958", "YJL146W", "P47011", "YJL137C", "Q06103", "YPR108W", "P21954", "YDL066W", "P16861", "YGR240C", "P17709", "YCL040W", "P23724", "YBL041W", "P50094", "YML056C", "P15274", "YML035C", "P33297", "YOR117W", "Q06204", "YLR446W", "Q03280", "YDR457W", "P38985", "YDL092W", "Q12377", "YDL097C", "P10592", "YLL024C", "P47079", "YJL008C", "P32873", "YPL115C", "P11633", "YBR089C-A", "P39960", "YER155C", "P32769", "YKR084C", "Q06549", "YLR245C", "P15891", "YCR088W", "Q12250", "YDL147W", "P04807", "YGL253W", "P00549", "YAL038W", "P50095", "YLR432W", "Q08491", "SKI7", "P23639", "YML092C", "Q12156", "YDR063W", "P39083", "YOR127W", "P53691", "YLR216C", "P32324", "EFT2", "P38697", "YHR216W", "P49435", "YML022W", "P02829", "YPL240C", "P38339", "YBR260C", "P39958", "YER136W", "P05373", "YGL040C", "Q05788", "YLR209C", "P06634", "YOR204W", "P38862", "YHR171W", "P40518", "YIL062C", "Q04409", "YDR516C", "P38150", "YJL070C", "Q06407", "YDR379W", "Q04062", "YDR427W", "P33299", "YKL145W", "P32464", "YKL189W", "P40016", "YER021W", "P15108", "YMR186W", "P39988", "YEL029C", "P43588", "YFR004W", "P36143", "YKR058W" ] }, "reaction_10774052": { "compartment": "compartment_876", "id": "reaction_10774052", "reactome": "R-SCE-2029471", "name": "Hydrolysis of PC to PA by PLD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_29356" ], "products": [ "species_264618", "species_1602448" ], "modifiers": [ [ "species_10774047", "catalyst" ] ], "additional_components": [ "YKR031C" ] }, "reaction_10772367": { "compartment": "compartment_70101", "id": "reaction_10772367", "reactome": "R-SCE-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10772360" ], "products": [ "species_111294", "species_10772356", "species_10772364", "species_76577" ], "modifiers": [ [ "species_10772267", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "Q08273", "YOL133W", "P22515", "YKL210W", "P15732", "YDR059C", "P38042", "YBL084C", "P52490", "UBC13", "Q04601", "YDR118W", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P52492", "YOR339C", "P06104", "YGL058W", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P53197", "YGL003C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "P52286", "YDR328C", "P28263", "YEL012W", "P54860", "YDL190C", "P26309", "YGL116W", "P33296", "YER100W", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P53152", "MMS2", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P20437", "YMR199W", "P21734", "YDR177W", "P53886", "YNL172W", "P39940", "YER125W", "Q12018", "YDL132W", "P24868", "YGR108W", "Q02159", "YMR022W", "Q05164", "YOL155C", "P15731", "YBR082C", "P24869", "YPR119W", "P25382", "YCR072C", "P52491", "YLR306W", "P19812", "YGR184C", "Q08683", "YOR249C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P32943", "YGR109C", "P14682", "YDR054C", "P30283", "YPR120C", "P16522", "YHR166C", "Q12347", "YLR097C", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P22515", "YKL210W", "P15732", "YDR059C", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P52491", "YLR306W", "P21734", "YDR177W", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P32943", "YGR109C", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C" ] }, "reaction_10783866": { "compartment": "compartment_6800424", "id": "reaction_10783866", "reactome": "R-SCE-6800426", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783854" ], "products": [ "species_10783864" ], "modifiers": [], "additional_components": [ "P38142", "YBR241C", "P37296", "YMR054W", "P32563", "YOR270C", "P38065", "YBL037W", "Q02647", "YDR424C", "P06780", "YPR165W", "P25353", "YCR026C", "P25515", "YEL027W", "P41810", "YDR238C", "P38142", "YBR241C", "P37296", "YMR054W", "P32563", "YOR270C", "P38065", "YBL037W", "Q02647", "YDR424C", "P06780", "YPR165W", "P25353", "YCR026C", "P25515", "YEL027W", "P41810", "YDR238C" ] }, "reaction_10772633": { "compartment": "compartment_1222693", "id": "reaction_10772633", "reactome": "R-SCE-1222516", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10772630", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "P23968", "YHR026W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10769326": { "compartment": "compartment_70101", "id": "reaction_10769326", "reactome": "R-SCE-418436", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29468", "species_29368" ], "products": [ "species_29366", "species_202124", "species_29968" ], "modifiers": [ [ "species_10769321", "catalyst" ] ], "additional_components": [ "YHR042W" ] }, "reaction_10767230": { "compartment": "compartment_7660", "id": "reaction_10767230", "reactome": "R-SCE-198669", "name": "p38MAPK phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767221", "species_29358" ], "products": [ "species_113582", "species_10767227" ], "modifiers": [ [ "species_10765922", "catalyst" ] ], "additional_components": [ "YBR028C", "YBR028C", "YLR113W" ] }, "reaction_10787198": { "compartment": "compartment_70101", "id": "reaction_10787198", "reactome": "R-SCE-8940641", "name": "THOP1 cleaves oligopeptide fragment (8-16aa)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983032" ], "products": [ "species_8955634" ], "modifiers": [ [ "species_10787195", "catalyst" ] ], "additional_components": [ "YCL057W" ] }, "reaction_10772582": { "compartment": "compartment_70101", "id": "reaction_10772582", "reactome": "R-SCE-1168373", "name": "PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_10765242", "species_33625", "species_114519" ], "products": [ "species_10765252" ], "modifiers": [], "additional_components": [ "YBL105C", "species_33625", "P24583", "YBL105C", "species_74016", "species_6797635" ] }, "reaction_10775012": { "compartment": "compartment_70101", "id": "reaction_10775012", "reactome": "R-SCE-3204303", "name": "MRE11 binds cytosolic DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_874088", "species_10775008" ], "products": [ "species_10775010" ], "modifiers": [], "additional_components": [ "P32829", "MRE11", "species_874088" ] }, "reaction_10783010": { "compartment": "compartment_6800173", "id": "reaction_10783010", "reactome": "R-SCE-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782978" ], "products": [ "species_10783008" ], "modifiers": [], "additional_components": [ "P49954", "YLR351C", "P36110", "YKR013W", "Q06549", "YLR245C", "P47033", "YJL078C", "P41912", "YOL110W", "P15891", "YCR088W", "P21954", "YDL066W", "Q10740", "YNL045W", "P43599", "YFR018C", "P07267", "YPL154C", "P40547", "YIL017C", "P33401", "YKL127W", "P47032", "YJL079C", "P49954", "YLR351C", "P36110", "YKR013W", "Q06549", "YLR245C", "P47033", "YJL078C", "P41912", "YOL110W", "P15891", "YCR088W", "P21954", "YDL066W", "Q10740", "YNL045W", "P43599", "YFR018C", "P07267", "YPL154C", "P40547", "YIL017C", "P33401", "YKL127W", "P47032", "YJL079C" ] }, "reaction_10770716": { "compartment": "compartment_7660", "id": "reaction_10770716", "reactome": "R-SCE-450333", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10770713" ], "products": [ "species_113582", "species_10770632" ], "modifiers": [ [ "species_10770705", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10774045": { "compartment": "compartment_876", "id": "reaction_10774045", "reactome": "R-SCE-2029468", "name": "Conversion of PA into DAG by PAP-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_29356" ], "products": [ "species_29372", "species_112275" ], "modifiers": [ [ "species_10774042", "catalyst" ] ], "additional_components": [ "Q05521", "YDR284C", "Q04396", "YDR503C" ] }, "reaction_10783692": { "compartment": "compartment_1470028", "id": "reaction_10783692", "reactome": "R-SCE-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783636" ], "products": [ "species_10783690" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "P17555", "YNL138W", "P06738", "YPR160W", "P40358", "YJL073W", "P39076", "YIL142W", "P02557", "YFL037W", "P36022", "YKR054C", "P32565", "YIL075C", "P17121", "YDR389W", "Q03630", "YML077W", "P50095", "YLR432W", "P53094", "YGL197W", "Q03862", "YDR101C", "P32381", "YDL029W", "Q04228", "YML013W", "P25694", "YDL126C", "P00812", "YPL111W", "P38697", "YHR216W", "P39958", "YER136W", "Q12229", "YDL091C", "Q08412", "YOR042W", "P50094", "YML056C", "P38626", "YIL043C", "P32634", "YER132C", "P40557", "YIL005W", "P24583", "YBL105C", "P47079", "YJL008C", "Q02933", "YPL123C", "P34227", "YBL064C", "P40568", "YIR010W", "P53843", "YNL265C", "P16892", "YBL016W", "P17555", "YNL138W", "P06738", "YPR160W", "P40358", "YJL073W", "P39076", "YIL142W", "P02557", "YFL037W", "P36022", "YKR054C", "P32565", "YIL075C", "P17121", "YDR389W", "Q03630", "YML077W", "P50095", "YLR432W", "P53094", "YGL197W", "Q03862", "YDR101C", "P32381", "YDL029W", "Q04228", "YML013W", "P25694", "YDL126C", "P00812", "YPL111W", "P38697", "YHR216W", "P39958", "YER136W", "Q12229", "YDL091C", "Q08412", "YOR042W", "P50094", "YML056C", "P38626", "YIL043C", "P32634", "YER132C", "P40557", "YIL005W", "P24583", "YBL105C", "P47079", "YJL008C", "Q02933", "YPL123C", "P34227", "YBL064C", "P40568", "YIR010W", "P53843", "YNL265C" ] }, "reaction_10783061": { "compartment": "compartment_6799713", "id": "reaction_10783061", "reactome": "R-SCE-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783055" ], "products": [ "species_10783059" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "P32660", "YER166W", "P38142", "YBR241C", "P39524", "YAL026C", "Q12675", "YDR093W", "P33328", "YOR327C", "Q02647", "YDR424C", "Q04359", "YMR017W", "P36126", "YKR031C", "P25515", "YEL027W", "P31109", "YAL030W", "Q12674", "YMR162C", "P41810", "YDR238C", "P40357", "YGR009C", "P38142", "YBR241C", "P33328", "YOR327C", "Q04359", "YMR017W", "P25515", "YEL027W", "P31109", "YAL030W", "P41810", "YDR238C", "P32660", "YER166W", "P39524", "YAL026C", "Q12675", "YDR093W", "Q02647", "YDR424C", "P36126", "YKR031C", "Q12674", "YMR162C" ] }, "reaction_10766032": { "compartment": "compartment_7660", "id": "reaction_10766032", "reactome": "R-SCE-168440", "name": "Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765963", "species_10765915" ], "products": [ "species_10766030" ], "modifiers": [], "additional_components": [ "YEL009C", "P39970", "YER045C", "P40535", "YIL036W", "Q02100", "YNL167C", "P39970", "YER045C", "P40535", "YIL036W", "P03069", "YEL009C", "Q02100", "YNL167C" ] }, "reaction_10772715": { "compartment": "compartment_70101", "id": "reaction_10772715", "reactome": "R-SCE-1247960", "name": "Activation of p38 MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10772704" ], "products": [ "species_29370", "species_10772712" ], "modifiers": [ [ "species_10770681", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P32485", "YLR113W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10783523": { "compartment": "compartment_6799371", "id": "reaction_10783523", "reactome": "R-SCE-6798749", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783509" ], "products": [ "species_10783521" ], "modifiers": [], "additional_components": [ "P00812", "YPL111W", "P49954", "YLR351C", "P36110", "YKR013W", "P47033", "YJL078C", "Q06142", "YLR347C", "Q06409", "YLR422W", "P43599", "YFR018C", "P07267", "YPL154C", "P40547", "YIL017C", "P27796", "YIL160C", "Q08412", "YOR042W", "P39988", "YEL029C", "P47032", "YJL079C", "P00812", "YPL111W", "P49954", "YLR351C", "P36110", "YKR013W", "P47033", "YJL078C", "Q06142", "YLR347C", "Q06409", "YLR422W", "P43599", "YFR018C", "P07267", "YPL154C", "P40547", "YIL017C", "P27796", "YIL160C", "Q08412", "YOR042W", "P39988", "YEL029C", "P47032", "YJL079C" ] }, "reaction_10770641": { "compartment": "compartment_7660", "id": "reaction_10770641", "reactome": "R-SCE-450222", "name": "Active p38 MAPK phosphorylates MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10770632" ], "products": [ "species_113582", "species_10770638" ], "modifiers": [ [ "species_10770632", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W" ] }, "reaction_10783779": { "compartment": "compartment_6799351", "id": "reaction_10783779", "reactome": "R-SCE-6799350", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783765" ], "products": [ "species_10783777" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "Q06144", "YLR350W", "P38142", "YBR241C", "P53142", "YGL104C", "P33328", "YOR327C", "P32901", "YKR093W", "Q00776", "YPL259C", "Q04359", "YMR017W", "P53224", "YGR038W", "P31109", "YAL030W", "P13856", "YGR152C", "P33333", "YDL052C", "P32660", "YER166W", "P39524", "YAL026C", "Q12675", "YDR093W", "Q04458", "YMR110C", "P36126", "YKR031C", "P32610", "YEL051W", "P25656", "YCR094W", "Q12674", "YMR162C", "Q12091", "YPL170W", "P40357", "YGR009C", "Q06144", "YLR350W", "P38142", "YBR241C", "P53142", "YGL104C", "P33328", "YOR327C", "P32901", "YKR093W", "Q00776", "YPL259C", "Q04359", "YMR017W", "P53224", "YGR038W", "P31109", "YAL030W", "P13856", "YGR152C", "P33333", "YDL052C", "P32660", "YER166W", "P39524", "YAL026C", "Q12675", "YDR093W", "Q04458", "YMR110C", "P36126", "YKR031C", "P32610", "YEL051W", "P25656", "YCR094W", "Q12674", "YMR162C", "Q12091", "YPL170W" ] }, "reaction_10771236": { "compartment": "compartment_70101", "id": "reaction_10771236", "reactome": "R-SCE-874087", "name": "SGT1 binds HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771232", "species_10771226" ], "products": [ "species_10771234" ], "modifiers": [], "additional_components": [ "P02829", "YPL240C", "P15108", "YMR186W", "YOR057W", "P02829", "YPL240C", "Q08446", "YOR057W", "P15108", "YMR186W" ] }, "reaction_10772405": { "compartment": "compartment_70101", "id": "reaction_10772405", "reactome": "R-SCE-983153", "name": "E1 mediated ubiquitin activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10760634", "species_10772397", "species_29926" ], "products": [ "species_111294", "species_76577", "species_10772399", "species_29926" ], "modifiers": [ [ "species_10772397", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "Q99344", "YPR066W", "P38862", "YHR171W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q99344", "YPR066W", "P38862", "YHR171W", "P22515", "YKL210W", "Q99344", "YPR066W", "P38862", "YHR171W" ] }, "reaction_10770762": { "compartment": "compartment_70101", "id": "reaction_10770762", "reactome": "R-SCE-450348", "name": "Activated human JNKs migrate to nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765974" ], "products": [ "species_10765931" ], "modifiers": [], "additional_components": [ "YPR054W", "YPR054W" ] }, "reaction_10782924": { "compartment": "compartment_876", "id": "reaction_10782924", "reactome": "R-SCE-6798743", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782878" ], "products": [ "species_10782922" ], "modifiers": [], "additional_components": [ "P40462", "YIL137C", "Q06144", "YLR350W", "P32454", "YKL157W", "Q00246", "YKR055W", "P06781", "YNL090W", "P38142", "YBR241C", "Q99260", "YLR262C", "P32563", "YOR270C", "P38065", "YBL037W", "P53224", "YGR038W", "P41810", "YDR238C", "P36017", "YOR089C", "P07560", "YFL005W", "Q00245", "YIL118W", "Q12280", "YPL242C", "P06780", "YPR165W", "P32939", "YML001W", "Q04458", "YMR110C", "P37898", "YHR047C", "P48559", "YNL304W", "P40462", "YIL137C", "Q06144", "YLR350W", "P32454", "YKL157W", "Q00246", "YKR055W", "P06781", "YNL090W", "P38142", "YBR241C", "Q99260", "YLR262C", "P32563", "YOR270C", "P38065", "YBL037W", "P53224", "YGR038W", "P41810", "YDR238C", "P36017", "YOR089C", "P07560", "YFL005W", "Q00245", "YIL118W", "Q12280", "YPL242C", "P06780", "YPR165W", "P32939", "YML001W", "Q04458", "YMR110C", "P37898", "YHR047C", "P48559", "YNL304W" ] }, "reaction_10772402": { "compartment": "compartment_70101", "id": "reaction_10772402", "reactome": "R-SCE-983152", "name": "Transfer of ubiquitin from E1 to E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772356", "species_10772399" ], "products": [ "species_10772358", "species_10772397" ], "modifiers": [ [ "species_10772356", "catalyst" ] ], "additional_components": [ "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P22515", "YKL210W", "P15732", "YDR059C", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P52491", "YLR306W", "P21734", "YDR177W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q99344", "YPR066W", "P38862", "YHR171W", "P22515", "YKL210W", "P15732", "YDR059C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P05759", "RPS31", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52491", "YLR306W", "P21734", "YDR177W", "P22515", "YKL210W", "Q99344", "YPR066W", "P38862", "YHR171W", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P22515", "YKL210W", "P15732", "YDR059C", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P52491", "YLR306W", "P21734", "YDR177W" ] }, "reaction_10774030": { "compartment": "compartment_70101", "id": "reaction_10774030", "reactome": "R-SCE-2029454", "name": "Autophosphorylation of PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774023", "species_113592" ], "products": [ "species_29370", "species_10774027", "species_10768894" ], "modifiers": [ [ "species_10768970", "catalyst" ] ], "additional_components": [ "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C", "YHL007C", "species_29438", "P19073", "YLR229C", "YHL007C" ] }, "reaction_10774276": { "compartment": "compartment_70101", "id": "reaction_10774276", "reactome": "R-SCE-2317332", "name": "PIP3 recruits AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10769080" ], "products": [ "species_10767182" ], "modifiers": [], "additional_components": [ "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "P11792", "YHR205W" ] }, "reaction_10772383": { "compartment": "compartment_70101", "id": "reaction_10772383", "reactome": "R-SCE-983150", "name": "Proteasomal cleavage of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983123" ], "products": [ "species_983032", "species_983036", "species_10760634", "species_8942986" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10784185": { "compartment": "compartment_984", "id": "reaction_10784185", "reactome": "R-SCE-6804100", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784177", "species_166005" ], "products": [ "species_10784183" ], "modifiers": [], "additional_components": [ "YBR089C-A", "species_166005", "P11633", "YBR089C-A" ] }, "reaction_10774162": { "compartment": "compartment_161320", "id": "reaction_10774162", "reactome": "R-SCE-2130706", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2213225" ], "products": [ "species_2213226" ], "modifiers": [ [ "species_10774157", "catalyst" ] ], "additional_components": [ "YPL154C" ] }, "reaction_10784181": { "compartment": "compartment_984", "id": "reaction_10784181", "reactome": "R-SCE-6804099", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784177", "species_181015" ], "products": [ "species_10784179" ], "modifiers": [], "additional_components": [ "YBR089C-A", "P11633", "YBR089C-A", "species_181015" ] }, "reaction_10770513": { "compartment": "compartment_70101", "id": "reaction_10770513", "reactome": "R-SCE-446877", "name": "TRAF6 is K63 poly-ubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770504" ], "products": [ "species_10770510" ], "modifiers": [ [ "species_10770504", "catalyst" ] ], "additional_components": [ "P43633", "YGL021W", "P32789", "YBL009W", "P05759", "RPS31", "P53152", "MMS2", "P52490", "UBC13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P43633", "YGL021W", "P32789", "YBL009W", "P53152", "MMS2", "P52490", "UBC13", "P43633", "YGL021W", "P32789", "YBL009W", "P05759", "RPS31", "P53152", "MMS2", "P52490", "UBC13", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10787872": { "compartment": "compartment_984", "id": "reaction_10787872", "reactome": "R-SCE-9008043", "name": "MAPK8 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10765968" ], "products": [ "species_29370", "species_10765974" ], "modifiers": [], "additional_components": [ "YPR054W", "YPR054W" ] }, "reaction_10772410": { "compartment": "compartment_70101", "id": "reaction_10772410", "reactome": "R-SCE-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772358", "species_10772267", "species_983035" ], "products": [ "species_10772360" ], "modifiers": [], "additional_components": [ "P22515", "YKL210W", "P15732", "YDR059C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P05759", "RPS31", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52491", "YLR306W", "P21734", "YDR177W", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P13365", "YAL040C", "Q08273", "YOL133W", "P22515", "YKL210W", "P15732", "YDR059C", "P38042", "YBL084C", "P52490", "UBC13", "Q04601", "YDR118W", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P52492", "YOR339C", "P06104", "YGL058W", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P53197", "YGL003C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "P52286", "YDR328C", "P28263", "YEL012W", "P54860", "YDL190C", "P26309", "YGL116W", "P33296", "YER100W", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P53152", "MMS2", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P20437", "YMR199W", "P21734", "YDR177W", "P53886", "YNL172W", "P39940", "YER125W", "Q12018", "YDL132W", "P24868", "YGR108W", "Q02159", "YMR022W", "Q05164", "YOL155C", "P15731", "YBR082C", "P24869", "YPR119W", "P25382", "YCR072C", "P52491", "YLR306W", "P19812", "YGR184C", "Q08683", "YOR249C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P32943", "YGR109C", "P14682", "YDR054C", "P30283", "YPR120C", "P16522", "YHR166C", "Q12347", "YLR097C" ] }, "reaction_10772644": { "compartment": "compartment_70101", "id": "reaction_10772644", "reactome": "R-SCE-1236970", "name": "Proteasomal clevage of exogenous antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236719" ], "products": [ "species_983036", "species_8942986" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10765954": { "compartment": "compartment_7660", "id": "reaction_10765954", "reactome": "R-SCE-168053", "name": "Phosphorylated MAPKs phosphorylate ATF-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10765901" ], "products": [ "species_113582", "species_10765915" ], "modifiers": [ [ "species_10765951", "catalyst" ] ], "additional_components": [ "P39970", "YER045C", "P40535", "YIL036W", "Q02100", "YNL167C", "P39970", "YER045C", "P40535", "YIL036W", "Q02100", "YNL167C", "P16892", "YBL016W", "P41808", "YPR054W", "Q00772", "YHR030C", "P32485", "YLR113W", "P14681", "YGR040W" ] }, "reaction_10784297": { "compartment": "compartment_984", "id": "reaction_10784297", "reactome": "R-SCE-6805981", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768264" ], "products": [ "species_10784177" ], "modifiers": [], "additional_components": [ "YBR089C-A", "YBR089C-A" ] }, "reaction_10769000": { "compartment": "compartment_70101", "id": "reaction_10769000", "reactome": "R-SCE-389788", "name": "Activation of PAKs by RAC1 and CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768994", "species_10768894" ], "products": [ "species_10768996", "species_10768998" ], "modifiers": [], "additional_components": [ "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "P48562", "YNL298W", "Q03497", "YHL007C", "species_29438", "Q12469", "YOL113W", "P19073", "YLR229C" ] }, "reaction_10770707": { "compartment": "compartment_70101", "id": "reaction_10770707", "reactome": "R-SCE-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770683" ], "products": [ "species_10770705" ], "modifiers": [], "additional_components": [ "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10772381": { "compartment": "compartment_70101", "id": "reaction_10772381", "reactome": "R-SCE-983147", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772379" ], "products": [ "species_10772267", "species_983123" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C" ] }, "reaction_10767125": { "compartment": "compartment_876", "id": "reaction_10767125", "reactome": "R-SCE-198314", "name": "DAG stimulates protein kinase C-delta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767110", "species_113592" ], "products": [ "species_29370", "species_10767117" ], "modifiers": [ [ "species_10767110", "catalyst" ], [ "species_112275", "catalyst" ] ], "additional_components": [ "YBL105C", "YBL105C", "YBL105C" ] }, "reaction_10782803": { "compartment": "compartment_6798757", "id": "reaction_10782803", "reactome": "R-SCE-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782785" ], "products": [ "species_10782801" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "P33767", "YEL002C", "P33328", "YOR327C", "Q03723", "YML019W", "P25515", "YEL027W", "P31109", "YAL030W", "P13856", "YGR152C", "P07560", "YFL005W", "P53337", "YGR284C", "P39524", "YAL026C", "P48439", "YOR085W", "P40075", "YER120W", "P25656", "YCR094W", "Q12674", "YMR162C", "P40357", "YGR009C", "P33767", "YEL002C", "P33328", "YOR327C", "Q03723", "YML019W", "P25515", "YEL027W", "P31109", "YAL030W", "P13856", "YGR152C", "P07560", "YFL005W", "P53337", "YGR284C", "P39524", "YAL026C", "P48439", "YOR085W", "P40075", "YER120W", "P25656", "YCR094W", "Q12674", "YMR162C" ] }, "reaction_10784060": { "compartment": "compartment_984", "id": "reaction_10784060", "reactome": "R-SCE-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784052" ], "products": [ "species_10784058" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "Q06625", "YPR184W", "P32807", "YMR284W", "P25043", "YOR157C", "P06738", "YPR160W", "P02994", "YBR118W", "P47103", "YJR032W", "Q03957", "YKL139W", "P04806", "YFR053C", "Q12096", "YOR320C", "Q03262", "YMR278W", "P38764", "YHR027C", "Q04120", "YDR453C", "P52489", "YOR347C", "Q08723", "YOR261C", "P38930", "CKB2", "P12709", "YBR196C", "P36010", "YKL067W", "P34760", "YML028W", "P32485", "YLR113W", "P32381", "YDL029W", "P32379", "YGR253C", "P38696", "YHR129C", "P16862", "YMR205C", "P40361", "YJL070C", "P25694", "YDL126C", "P15202", "YDR256C", "P46958", "YJL146W", "P47011", "YJL137C", "Q06142", "YLR347C", "Q06103", "YPR108W", "P21954", "YDL066W", "P16861", "YGR240C", "P17709", "YCL040W", "P23724", "YBL041W", "P33401", "YKL127W", "P50094", "YML056C", "P15274", "YML035C", "P33297", "YOR117W", "Q06204", "YLR446W", "Q10740", "YNL045W", "Q03280", "YDR457W", "P38985", "YDL092W", "Q12377", "YDL097C", "P10592", "YLL024C", "P47079", "YJL008C", "P11633", "YBR089C-A", "P16892", "YBL016W", "P32769", "YKR084C", "Q06549", "YLR245C", "P15891", "YCR088W", "Q12250", "YDL147W", "P04807", "YGL253W", "P00549", "YAL038W", "P50095", "YLR432W", "Q08491", "SKI7", "P23639", "YML092C", "Q12156", "YDR063W", "P53691", "YLR216C", "P32324", "EFT2", "P38697", "YHR216W", "P02829", "YPL240C", "P05373", "YGL040C", "Q05788", "YLR209C", "P06634", "YOR204W", "P38862", "YHR171W", "P40518", "YIL062C", "Q04409", "YDR516C", "P38150", "YJL070C", "Q04062", "YDR427W", "P33299", "YKL145W", "P32464", "YKL189W", "P43599", "YFR018C", "P07267", "YPL154C", "P40016", "YER021W", "P15108", "YMR186W", "P43588", "YFR004W", "P36143", "YKR058W", "P06787", "YBR109C", "Q06625", "YPR184W", "P32807", "YMR284W", "P25043", "YOR157C", "P06738", "YPR160W", "P02994", "YBR118W", "P47103", "YJR032W", "Q03957", "YKL139W", "P04806", "YFR053C", "Q12096", "YOR320C", "Q03262", "YMR278W", "P38764", "YHR027C", "Q04120", "YDR453C", "P52489", "YOR347C", "Q08723", "YOR261C", "P38930", "CKB2", "P12709", "YBR196C", "P36010", "YKL067W", "P34760", "YML028W", "P32485", "YLR113W", "P32381", "YDL029W", "P32379", "YGR253C", "P38696", "YHR129C", "P16862", "YMR205C", "P40361", "YJL070C", "P25694", "YDL126C", "P15202", "YDR256C", "P46958", "YJL146W", "P47011", "YJL137C", "Q06142", "YLR347C", "Q06103", "YPR108W", "P21954", "YDL066W", "P16861", "YGR240C", "P17709", "YCL040W", "P23724", "YBL041W", "P33401", "YKL127W", "P50094", "YML056C", "P15274", "YML035C", "P33297", "YOR117W", "Q06204", "YLR446W", "Q10740", "YNL045W", "Q03280", "YDR457W", "P38985", "YDL092W", "Q12377", "YDL097C", "P10592", "YLL024C", "P47079", "YJL008C", "P11633", "YBR089C-A", "P16892", "YBL016W", "P32769", "YKR084C", "Q06549", "YLR245C", "P15891", "YCR088W", "Q12250", "YDL147W", "P04807", "YGL253W", "P00549", "YAL038W", "P50095", "YLR432W", "Q08491", "SKI7", "P23639", "YML092C", "Q12156", "YDR063W", "P53691", "YLR216C", "P32324", "EFT2", "P38697", "YHR216W", "P02829", "YPL240C", "P05373", "YGL040C", "Q05788", "YLR209C", "P06634", "YOR204W", "P38862", "YHR171W", "P40518", "YIL062C", "Q04409", "YDR516C", "P38150", "YJL070C", "Q04062", "YDR427W", "P33299", "YKL145W", "P32464", "YKL189W", "P43599", "YFR018C", "P07267", "YPL154C", "P40016", "YER021W", "P15108", "YMR186W", "P43588", "YFR004W", "P36143", "YKR058W" ] }, "reaction_10765966": { "compartment": "compartment_7660", "id": "reaction_10765966", "reactome": "R-SCE-168136", "name": "Activated JNKs phosphorylate c-JUN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765959", "species_29358" ], "products": [ "species_10765963", "species_113582" ], "modifiers": [ [ "species_10765931", "catalyst" ] ], "additional_components": [ "YEL009C", "YEL009C", "YPR054W" ] }, "reaction_10772458": { "compartment": "compartment_70101", "id": "reaction_10772458", "reactome": "R-SCE-983162", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983036" ], "products": [ "species_983032", "species_8942986" ], "modifiers": [ [ "species_10772455", "catalyst" ] ], "additional_components": [ "P40462", "YIL137C", "P32454", "YKL157W", "P37898", "YHR047C", "Q01532", "YNL239W" ] }, "reaction_10768965": { "compartment": "compartment_70101", "id": "reaction_10768965", "reactome": "R-SCE-389756", "name": "AKT interacts and phosphorylates Cot", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768955", "species_113592" ], "products": [ "species_29370", "species_10768963" ], "modifiers": [ [ "species_10767105", "catalyst" ] ], "additional_components": [ "P25390", "YCR073C", "P53599", "YNR031C", "P25390", "YCR073C", "P53599", "YNR031C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10770645": { "compartment": "compartment_70101", "id": "reaction_10770645", "reactome": "R-SCE-450257", "name": "Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770638" ], "products": [ "species_10770643" ], "modifiers": [], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W" ] }, "reaction_10766862": { "compartment": "compartment_17951", "id": "reaction_10766862", "reactome": "R-SCE-193508", "name": "(24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193732", "species_192307" ], "products": [ "species_193465", "species_193403", "species_192305" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10786503": { "compartment": "compartment_70101", "id": "reaction_10786503", "reactome": "R-SCE-8867667", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399" ], "products": [ "species_8868400" ], "modifiers": [ [ "species_10786500", "catalyst" ] ], "additional_components": [ "P38713", "YHR073W", "Q12451", "YDL019C", "P35845", "YAR042W", "P35844", "YPL145C" ] }, "reaction_10766816": { "compartment": "compartment_70101", "id": "reaction_10766816", "reactome": "R-SCE-191983", "name": "Cholesterol is hydroxylated to 25-hydroxycholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_176478", "species_29368" ], "products": [ "species_29366", "species_192148", "species_29356" ], "modifiers": [ [ "species_10766813", "catalyst" ] ], "additional_components": [ "species_111793", "P53045", "YGR060W" ] }, "reaction_10766860": { "compartment": "compartment_17951", "id": "reaction_10766860", "reactome": "R-SCE-193455", "name": "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193422", "species_192307" ], "products": [ "species_193465", "species_192305", "species_192339" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10766864": { "compartment": "compartment_17951", "id": "reaction_10766864", "reactome": "R-SCE-193535", "name": "25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_193459" ], "products": [ "species_193732" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10766824": { "compartment": "compartment_70101", "id": "reaction_10766824", "reactome": "R-SCE-192097", "name": "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192114", "species_29360" ], "products": [ "species_70106", "species_73473", "species_192136" ], "modifiers": [ [ "species_10766821", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10766868": { "compartment": "compartment_70101", "id": "reaction_10766868", "reactome": "R-SCE-193789", "name": "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192189", "species_29360" ], "products": [ "species_70106", "species_73473", "species_193724" ], "modifiers": [ [ "species_10766821", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10786538": { "compartment": "compartment_70101", "id": "reaction_10786538", "reactome": "R-SCE-8868402", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399", "species_1806217" ], "products": [ "species_1806234", "species_8868393" ], "modifiers": [ [ "species_10786535", "catalyst" ] ], "additional_components": [ "P38713", "YHR073W", "Q12451", "YDL019C", "P35845", "YAR042W" ] }, "reaction_10766870": { "compartment": "compartment_70101", "id": "reaction_10766870", "reactome": "R-SCE-193816", "name": "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192194", "species_29360" ], "products": [ "species_70106", "species_73473", "species_193835" ], "modifiers": [ [ "species_10766821", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10766834": { "compartment": "compartment_17951", "id": "reaction_10766834", "reactome": "R-SCE-192331", "name": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192342", "species_141343" ], "products": [ "species_193422" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10766857": { "compartment": "compartment_17951", "id": "reaction_10766857", "reactome": "R-SCE-193385", "name": "Hydrolysis of choloyl-CoA to cholate and CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192356", "species_141343" ], "products": [ "species_193514", "species_193451" ], "modifiers": [ [ "species_10766854", "catalyst" ] ], "additional_components": [ "YJR019C" ] }, "reaction_10785978": { "compartment": "compartment_5683628", "id": "reaction_10785978", "reactome": "R-SCE-8854588", "name": "TBC1D25 (OATL1) binds ATG8 homologues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779200", "species_10785974" ], "products": [ "species_10785976" ], "modifiers": [], "additional_components": [ "YBL078C", "YDL234C", "P48365", "YDL234C", "P38182", "YBL078C" ] }, "reaction_10786878": { "compartment": "compartment_263163", "id": "reaction_10786878", "reactome": "R-SCE-8876193", "name": "RIC1-RGP1 exchanges GTP for GDP on RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786865", "species_29438" ], "products": [ "species_10786790", "species_10786869", "species_29420" ], "modifiers": [ [ "species_10786875", "catalyst" ] ], "additional_components": [ "species_29420", "Q99260", "YLR262C", "P39958", "YER136W", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "Q99260", "YLR262C", "species_29438", "P16664", "YDR137W", "P40395", "YLR039C" ] }, "reaction_10785971": { "compartment": "compartment_17938", "id": "reaction_10785971", "reactome": "R-SCE-8854329", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785946", "species_29356" ], "products": [ "species_10785964", "species_29372" ], "modifiers": [ [ "species_10785946", "catalyst" ], [ "species_10785969", "catalyst" ] ], "additional_components": [ "P32939", "YML001W", "CHEBI:15996", "P32939", "YML001W", "species_111349", "P32939", "YML001W", "CHEBI:15996", "YDL234C" ] }, "reaction_10785951": { "compartment": "compartment_17938", "id": "reaction_10785951", "reactome": "R-SCE-8854255", "name": "TBC1D2A accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785946", "species_29356" ], "products": [ "species_29372", "species_10785948" ], "modifiers": [ [ "species_10785946", "catalyst" ] ], "additional_components": [ "P32939", "YML001W", "CHEBI:15996", "species_29420", "P32939", "YML001W", "P32939", "YML001W", "CHEBI:15996" ] }, "reaction_10786851": { "compartment": "compartment_263163", "id": "reaction_10786851", "reactome": "R-SCE-8876190", "name": "RAB8 GEFs exchange GTP for GDP on RAB8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10786842" ], "products": [ "species_10786790", "species_10786848", "species_29420" ], "modifiers": [ [ "species_10778221", "catalyst" ] ], "additional_components": [ "species_29420", "P07560", "YFL005W", "P39958", "YER136W", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "P07560", "YFL005W", "species_29438", "YNL272C" ] }, "reaction_10785960": { "compartment": "compartment_20699", "id": "reaction_10785960", "reactome": "R-SCE-8854303", "name": "TBC1D11 binds RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785468", "species_10785956" ], "products": [ "species_10785958" ], "modifiers": [], "additional_components": [ "Q99260", "YLR262C", "species_29438", "YPL249C", "Q99260", "YLR262C", "Q12344", "YPL249C", "species_29438" ] }, "reaction_10786959": { "compartment": "compartment_13946", "id": "reaction_10786959", "reactome": "R-SCE-8877475", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10786946" ], "products": [ "species_10786790", "species_29420", "species_10786956" ], "modifiers": [ [ "species_10781391", "catalyst" ] ], "additional_components": [ "species_29420", "P39958", "YER136W", "P01123", "YFL038C", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "P01123", "YFL038C", "species_29438", "P38334", "YBR254C", "Q03630", "YML077W", "Q03784", "YDR246W", "P36149", "YKR068C", "Q04183", "YDR407C", "Q03337", "YDR472W", "Q03660", "YMR218C", "Q99394", "YOR115C" ] }, "reaction_10786801": { "compartment": "compartment_216813", "id": "reaction_10786801", "reactome": "R-SCE-8875318", "name": "RAB3 GEFs exchange GTP for GDP on RAB3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10786792" ], "products": [ "species_10786790", "species_10786796", "species_29420" ], "modifiers": [ [ "species_10786798", "catalyst" ] ], "additional_components": [ "P07560", "YFL005W", "species_29420", "P39958", "YER136W", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "P07560", "YFL005W", "species_29438", "YNL272C" ] }, "reaction_10786938": { "compartment": "compartment_17938", "id": "reaction_10786938", "reactome": "R-SCE-8877451", "name": "MON1:CCZ1 exchanges GTP for GDP on RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10786915" ], "products": [ "species_10786790", "species_10786921", "species_29420" ], "modifiers": [ [ "species_10786935", "catalyst" ] ], "additional_components": [ "species_29420", "P39958", "YER136W", "P32939", "YML001W", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "P32939", "YML001W", "species_29438", "P38273", "YBR131W", "P53129", "YGL124C" ] }, "reaction_10771192": { "compartment": "compartment_70101", "id": "reaction_10771192", "reactome": "R-SCE-727749", "name": "SLC29A3 transports nucleosides from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727782" ], "products": [ "species_727746" ], "modifiers": [ [ "species_10771189", "catalyst" ] ], "additional_components": [ "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "species_83951", "CHEBI:16704", "species_83909", "CHEBI:16750", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "species_83951", "CHEBI:16704", "species_83909", "CHEBI:16750", "YAL022C" ] }, "reaction_10764488": { "compartment": "compartment_70101", "id": "reaction_10764488", "reactome": "R-SCE-109534", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179743" ], "products": [ "species_179737" ], "modifiers": [ [ "species_10764480", "catalyst" ] ], "additional_components": [ "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83909", "CHEBI:16750", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83909", "CHEBI:16750", "YAL022C" ] }, "reaction_10765594": { "compartment": "compartment_70616", "id": "reaction_10765594", "reactome": "R-SCE-163215", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113592", "species_113581" ], "modifiers": [ [ "species_10765591", "catalyst" ] ], "additional_components": [ "P18239", "YBL030C", "P18238", "YBR085W", "P04710", "AAC1" ] }, "reaction_10764483": { "compartment": "compartment_70101", "id": "reaction_10764483", "reactome": "R-SCE-109527", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179747" ], "products": [ "species_179742" ], "modifiers": [ [ "species_10764478", "catalyst" ] ], "additional_components": [ "species_113599", "CHEBI:17821", "species_29554", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83951", "species_83909", "CHEBI:16040", "CHEBI:16750", "species_83956", "species_113599", "CHEBI:17821", "species_29554", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83951", "species_83909", "CHEBI:16040", "CHEBI:16750", "species_83956", "YAL022C" ] }, "reaction_10764485": { "compartment": "compartment_70101", "id": "reaction_10764485", "reactome": "R-SCE-109529", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179742" ], "products": [ "species_179747" ], "modifiers": [ [ "species_10764478", "catalyst" ] ], "additional_components": [ "species_113599", "CHEBI:17821", "species_29554", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83951", "species_83909", "CHEBI:16040", "CHEBI:16750", "species_83956", "species_113599", "CHEBI:17821", "species_29554", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83951", "species_83909", "CHEBI:16040", "CHEBI:16750", "species_83956", "YAL022C" ] }, "reaction_10764490": { "compartment": "compartment_70101", "id": "reaction_10764490", "reactome": "R-SCE-109536", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179737" ], "products": [ "species_179743" ], "modifiers": [ [ "species_10764480", "catalyst" ] ], "additional_components": [ "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83909", "CHEBI:16750", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83909", "CHEBI:16750", "YAL022C" ] }, "reaction_10774173": { "compartment": "compartment_5460", "id": "reaction_10774173", "reactome": "R-SCE-2162186", "name": "DeMQ10H2 is methylated to Q10H2 by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162212", "species_2162265" ], "products": [ "species_2162252", "species_2162198", "species_113529" ], "modifiers": [ [ "species_10774170", "catalyst" ] ], "additional_components": [ "YOL096C" ] }, "reaction_10774183": { "compartment": "compartment_5460", "id": "reaction_10774183", "reactome": "R-SCE-2162193", "name": "DHDB is methylated to MHDB by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162209", "species_2162265" ], "products": [ "species_2162252", "species_2162215", "species_113529" ], "modifiers": [ [ "species_10774170", "catalyst" ] ], "additional_components": [ "YOL096C" ] }, "reaction_10774197": { "compartment": "compartment_5460", "id": "reaction_10774197", "reactome": "R-SCE-2162253", "name": "FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162256", "species_2162257" ], "products": [ "species_2162214", "species_159450" ], "modifiers": [ [ "species_10774194", "catalyst" ] ], "additional_components": [ "P18900", "YBR003W", "species_109496" ] }, "reaction_10768904": { "compartment": "compartment_70101", "id": "reaction_10768904", "reactome": "R-SCE-389540", "name": "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_389545" ], "products": [ "species_70106", "species_29364", "species_113528", "species_29406" ], "modifiers": [ [ "species_10768901", "catalyst" ] ], "additional_components": [ "P21954", "YDL066W" ] }, "reaction_10773350": { "compartment": "compartment_70101", "id": "reaction_10773350", "reactome": "R-SCE-1497796", "name": "BH2 binding can lead to eNOS uncoupling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767639", "species_1497857" ], "products": [ "species_29870", "species_10773348" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "species_29870", "species_113596", "P11792", "YHR205W", "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "species_1497857", "species_29870", "P15108", "YMR186W", "species_113596", "P11792", "YHR205W" ] }, "reaction_10772915": { "compartment": "compartment_70101", "id": "reaction_10772915", "reactome": "R-SCE-1474146", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29356" ], "products": [ "species_1474124", "species_29460" ], "modifiers": [ [ "species_10772912", "catalyst" ], [ "species_29502", "catalyst" ], [ "species_29870", "inhibitor" ] ], "additional_components": [ "P51601", "YGR267C" ] }, "reaction_10774180": { "compartment": "compartment_70616", "id": "reaction_10774180", "reactome": "R-SCE-2162192", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162214", "species_2162213" ], "products": [ "species_2162207", "species_159450" ], "modifiers": [ [ "species_10774177", "catalyst" ] ], "additional_components": [] }, "reaction_10781221": { "compartment": "compartment_7660", "id": "reaction_10781221", "reactome": "R-SCE-5693566", "name": "TP53BP1 associates with H4K20Me2 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779351", "species_10774864" ], "products": [ "species_10779374" ], "modifiers": [], "additional_components": [ "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "YDR217C", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P14737", "YDR217C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10777638": { "compartment": "compartment_7660", "id": "reaction_10777638", "reactome": "R-SCE-5358513", "name": "MSH2:MSH3 binds insertion/deletion loop of 2 bases or more", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358527", "species_10777634" ], "products": [ "species_10777636" ], "modifiers": [], "additional_components": [ "P25336", "YCR092C", "species_29370", "P25847", "YOL090W", "P25336", "YCR092C", "species_29370", "P25847", "YOL090W" ] }, "reaction_10781856": { "compartment": "compartment_7660", "id": "reaction_10781856", "reactome": "R-SCE-6782211", "name": "DNA polymerases delta, epsilon or kappa bind the TC-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781852", "species_10760923", "species_10764822", "species_10781840" ], "products": [ "species_10781854" ], "modifiers": [], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P15873", "YBR088C", "P40348", "YJR068W", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P22336", "YAR007C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P06777", "YPL022W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P26754", "YNL312W", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P22336", "YAR007C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P32523", "YLL036C", "P0CH08", "RPL40A", "P07273", "YGL043W", "P38251", "YBR087W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "P28519", "YMR201C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P06777", "YPL022W", "Q04048", "YDR416W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P26754", "YNL312W", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10778491": { "compartment": "compartment_7660", "id": "reaction_10778491", "reactome": "R-SCE-5655466", "name": "USP1:WDR48 deubiquitinates monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778486" ], "products": [ "species_10778488", "species_10778482", "species_10760537" ], "modifiers": [ [ "species_10778486", "catalyst" ] ], "additional_components": [ "P38630", "YOR217W", "P40339", "YOL094C", "Q99247", "YOL087C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P36026", "YKR098C", "P26754", "YNL312W", "P25037", "YDL122W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P39967", "YER098W", "P15873", "YBR088C", "P40453", "YIL156W", "P38187", "YBL067C", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P36026", "YKR098C", "Q99247", "YOL087C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38630", "YOR217W", "P40339", "YOL094C", "Q99247", "YOL087C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P36026", "YKR098C", "P26754", "YNL312W", "P25037", "YDL122W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P39967", "YER098W", "P15873", "YBR088C", "P40453", "YIL156W", "P38187", "YBL067C" ] }, "reaction_10777795": { "compartment": "compartment_7660", "id": "reaction_10777795", "reactome": "R-SCE-5444511", "name": "Formation of MSH2:MSH3 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10777614", "species_10777632" ], "products": [ "species_10777634" ], "modifiers": [], "additional_components": [ "YOL090W", "YCR092C", "P25336", "YCR092C", "species_29370", "P25847", "YOL090W" ] }, "reaction_10779178": { "compartment": "compartment_7660", "id": "reaction_10779178", "reactome": "R-SCE-5682044", "name": "KAT5 acetylates ATM at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779173", "species_113560" ], "products": [ "species_10779175", "species_2485002" ], "modifiers": [ [ "species_10779173", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10781860": { "compartment": "compartment_7660", "id": "reaction_10781860", "reactome": "R-SCE-6782227", "name": "Ligation of newly synthesized repair patch to incised DNA in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781847" ], "products": [ "species_10781049", "species_10781858" ], "modifiers": [ [ "species_10760994", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P38251", "YBR087W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "YDL164C" ] }, "reaction_10781753": { "compartment": "compartment_7660", "id": "reaction_10781753", "reactome": "R-SCE-6781867", "name": "ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781734", "species_10760537" ], "products": [ "species_10781750" ], "modifiers": [ [ "species_10781734", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P0CH08", "RPL40A", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10764704": { "compartment": "compartment_7660", "id": "reaction_10764704", "reactome": "R-SCE-110226", "name": "Cleavage of cytosine glycol by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764701" ], "products": [ "species_110225", "species_10764694" ], "modifiers": [ [ "species_10764701", "catalyst" ] ], "additional_components": [ "Q08214", "YOL043C", "Q08214", "YOL043C", "Q08214", "YOL043C" ] }, "reaction_10764171": { "compartment": "compartment_7660", "id": "reaction_10764171", "reactome": "R-SCE-75998", "name": "Formation of RAD52 heptameric ring structure complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764167" ], "products": [ "species_10764169" ], "modifiers": [], "additional_components": [ "YML032C", "P06778", "YML032C" ] }, "reaction_10764737": { "compartment": "compartment_7660", "id": "reaction_10764737", "reactome": "R-SCE-110244", "name": "Excision of FapyG by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764734" ], "products": [ "species_10764729", "species_5636006" ], "modifiers": [ [ "species_10764734", "catalyst" ] ], "additional_components": [ "P53397", "YML060W", "P53397", "YML060W", "P53397", "YML060W" ] }, "reaction_10781817": { "compartment": "compartment_7660", "id": "reaction_10781817", "reactome": "R-SCE-6782131", "name": "ERCC2-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781803" ], "products": [ "species_113582", "species_113550", "species_10781814" ], "modifiers": [ [ "species_10781803", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10779347": { "compartment": "compartment_7660", "id": "reaction_10779347", "reactome": "R-SCE-5682983", "name": "ATM phosphorylates WHSC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779342" ], "products": [ "species_113582", "species_10779337" ], "modifiers": [ [ "species_10779342", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10779385": { "compartment": "compartment_7660", "id": "reaction_10779385", "reactome": "R-SCE-5683425", "name": "ATM phosphorylates TP53BP1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779374" ], "products": [ "species_113582", "species_10779372" ], "modifiers": [ [ "species_10779374", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P14737", "YDR217C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P14737", "YDR217C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P14737", "YDR217C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10779325": { "compartment": "compartment_7660", "id": "reaction_10779325", "reactome": "R-SCE-5682858", "name": "RNF8 and RNF168 ubiquitinate H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779300", "species_10760537" ], "products": [ "species_10779322" ], "modifiers": [ [ "species_10779300", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10764711": { "compartment": "compartment_7660", "id": "reaction_10764711", "reactome": "R-SCE-110227", "name": "Cleavage of dihydrouracil by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764708" ], "products": [ "species_30140", "species_10764694" ], "modifiers": [ [ "species_10764708", "catalyst" ] ], "additional_components": [ "Q08214", "YOL043C", "Q08214", "YOL043C", "Q08214", "YOL043C" ] }, "reaction_10779340": { "compartment": "compartment_7660", "id": "reaction_10779340", "reactome": "R-SCE-5682965", "name": "WHSC1 dimethylates histone H4 on lysine K21 at DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779337", "species_77087" ], "products": [ "species_10779251", "species_77502" ], "modifiers": [ [ "species_10779337", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10779472": { "compartment": "compartment_7660", "id": "reaction_10779472", "reactome": "R-SCE-5685230", "name": "CHEK1 phosphorylates RAD51", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779467", "species_29358" ], "products": [ "species_113582", "species_10779470" ], "modifiers": [ [ "species_10761086", "catalyst" ] ], "additional_components": [ "YER095W", "YER095W", "P36002", "YKL198C", "P47116", "YJR059W", "P06782", "YDR477W" ] }, "reaction_10777660": { "compartment": "compartment_7660", "id": "reaction_10777660", "reactome": "R-SCE-5358597", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777656", "species_10777640" ], "products": [ "species_10777658" ], "modifiers": [], "additional_components": [ "YOR033C", "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W", "P14242", "YNL082W", "P38920", "YMR167W", "P39875", "YOR033C", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W" ] }, "reaction_10763954": { "compartment": "compartment_7660", "id": "reaction_10763954", "reactome": "R-SCE-75172", "name": "Formation of RAD50:MRE11 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763950", "species_981774" ], "products": [ "species_10763952" ], "modifiers": [], "additional_components": [ "P32829", "MRE11", "P12753", "DNA repair protein RAD50" ] }, "reaction_10777627": { "compartment": "compartment_7660", "id": "reaction_10777627", "reactome": "R-SCE-5358510", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777623", "species_10777609", "species_10760934" ], "products": [ "species_10777625" ], "modifiers": [], "additional_components": [ "species_113592", "Q03834", "YDR097C", "P25847", "YOL090W", "P14242", "YNL082W", "P38920", "YMR167W", "P15873", "YBR088C", "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W" ] }, "reaction_10779284": { "compartment": "compartment_7660", "id": "reaction_10779284", "reactome": "R-SCE-5682607", "name": "PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10779267" ], "products": [ "species_10774805", "species_10779281" ], "modifiers": [ [ "species_10779267", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "YDL064W", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10781725": { "compartment": "compartment_7660", "id": "reaction_10781725", "reactome": "R-SCE-6781840", "name": "ERCC6 binds stalled RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781721", "species_10781713" ], "products": [ "species_10781723" ], "modifiers": [], "additional_components": [ "YJR035W", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P20434", "RPB5", "P40352", "YJR035W", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10779259": { "compartment": "compartment_7660", "id": "reaction_10779259", "reactome": "R-SCE-5682588", "name": "RNF8 binds phosphorylated MDC1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779220", "species_10779255" ], "products": [ "species_10779257" ], "modifiers": [], "additional_components": [ "P53924", "YNL116W", "species_158417", "P32829", "MRE11", "P46995", "YJL168C", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10764718": { "compartment": "compartment_7660", "id": "reaction_10764718", "reactome": "R-SCE-110229", "name": "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764715" ], "products": [ "species_5637659", "species_10764694" ], "modifiers": [ [ "species_10764715", "catalyst" ] ], "additional_components": [ "Q08214", "YOL043C", "Q08214", "YOL043C", "Q08214", "YOL043C" ] }, "reaction_10779296": { "compartment": "compartment_7660", "id": "reaction_10779296", "reactome": "R-SCE-5682629", "name": "HERC2 facilitates UBE2N:UBE2V2 binding to RNF8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779290", "species_10779281" ], "products": [ "species_10779294" ], "modifiers": [], "additional_components": [ "P53152", "MMS2", "P52490", "UBC13", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10778520": { "compartment": "compartment_7660", "id": "reaction_10778520", "reactome": "R-SCE-5655483", "name": "USP1 autocleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778482" ], "products": [ "species_10778480", "species_10778517", "species_10778505" ], "modifiers": [ [ "species_10778482", "catalyst" ] ], "additional_components": [ "P36026", "YKR098C", "Q99247", "YOL087C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "YOL087C", "P36026", "YKR098C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "P36026", "YKR098C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "P36026", "YKR098C", "Q99247", "YOL087C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C" ] }, "reaction_10779349": { "compartment": "compartment_7660", "id": "reaction_10779349", "reactome": "R-SCE-5682992", "name": "KDM4A,B bind H4K20Me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779253", "species_10779251" ], "products": [ "species_10779255" ], "modifiers": [], "additional_components": [ "Q03833", "YDR096W", "P39956", "YER169W", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10781843": { "compartment": "compartment_7660", "id": "reaction_10781843", "reactome": "R-SCE-6782204", "name": "5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781838" ], "products": [ "species_10781840" ], "modifiers": [ [ "species_10781838", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P06777", "YPL022W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P22336", "YAR007C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P06777", "YPL022W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P26754", "YNL312W", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P06777", "YPL022W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10781711": { "compartment": "compartment_7660", "id": "reaction_10781711", "reactome": "R-SCE-6781818", "name": "RNA Pol II initiates transcription from damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762310", "species_5688114", "species_10763293" ], "products": [ "species_10781709" ], "modifiers": [], "additional_components": [ "P20433", "YJL140W", "P20434", "RPB5", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P20435", "RPO26", "P04050", "YDL140C", "P40422", "RPC10", "P38902", "YOL005C", "P34087", "YDR404C", "P22139", "RPB10", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10781209": { "compartment": "compartment_7660", "id": "reaction_10781209", "reactome": "R-SCE-5693536", "name": "ATM phosphorylates MDC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781206" ], "products": [ "species_113582", "species_10779335" ], "modifiers": [ [ "species_10781206", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10764732": { "compartment": "compartment_7660", "id": "reaction_10764732", "reactome": "R-SCE-110243", "name": "Excision of 8-oxoguanine by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764727" ], "products": [ "species_10764729", "species_110242" ], "modifiers": [ [ "species_10764727", "catalyst" ] ], "additional_components": [ "P53397", "YML060W", "P53397", "YML060W", "P53397", "YML060W" ] }, "reaction_10781219": { "compartment": "compartment_7660", "id": "reaction_10781219", "reactome": "R-SCE-5693549", "name": "ATM phosphorylates histone H2AFX on S139 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781216" ], "products": [ "species_113582", "species_10779442" ], "modifiers": [ [ "species_10781216", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10781716": { "compartment": "compartment_7660", "id": "reaction_10781716", "reactome": "R-SCE-6781824", "name": "Active RNA Pol II complex transcribes lesion-containing DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781709", "species_6781829" ], "products": [ "species_10781713", "species_113541" ], "modifiers": [ [ "species_10781709", "catalyst" ] ], "additional_components": [ "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10788944": { "compartment": "compartment_70101", "id": "reaction_10788944", "reactome": "R-SCE-9656947", "name": "OGG1beta translocates to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788940" ], "products": [ "species_10788942" ], "modifiers": [], "additional_components": [ "YML060W", "YML060W" ] }, "reaction_10777662": { "compartment": "compartment_7660", "id": "reaction_10777662", "reactome": "R-SCE-5358912", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10777647" ], "products": [ "species_113582", "species_10777623" ], "modifiers": [], "additional_components": [ "species_29370", "Q03834", "YDR097C", "P25847", "YOL090W", "species_113592", "Q03834", "YDR097C", "P25847", "YOL090W" ] }, "reaction_10781224": { "compartment": "compartment_7660", "id": "reaction_10781224", "reactome": "R-SCE-5693598", "name": "ATM phosphorylates NBN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781211" ], "products": [ "species_113582", "species_10779232" ], "modifiers": [ [ "species_10781211", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10779344": { "compartment": "compartment_7660", "id": "reaction_10779344", "reactome": "R-SCE-5682967", "name": "WHSC1 binds DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776856", "species_10779335" ], "products": [ "species_10779342" ], "modifiers": [], "additional_components": [ "YJL168C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10779366": { "compartment": "compartment_7660", "id": "reaction_10779366", "reactome": "R-SCE-5683077", "name": "RNF8 and RNF168 ubiquitinate KDM4A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779322", "species_10760537" ], "products": [ "species_10779351", "species_10779363" ], "modifiers": [ [ "species_10779322", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "Q03833", "YDR096W", "P39956", "YER169W", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10781240": { "compartment": "compartment_7660", "id": "reaction_10781240", "reactome": "R-SCE-5693602", "name": "ATM recognizes H2AFX-Nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779432", "species_10779232" ], "products": [ "species_10781216" ], "modifiers": [], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10764697": { "compartment": "compartment_7660", "id": "reaction_10764697", "reactome": "R-SCE-110224", "name": "Cleavage of thymine glycol by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764692" ], "products": [ "species_110223", "species_10764694" ], "modifiers": [ [ "species_10764692", "catalyst" ] ], "additional_components": [ "Q08214", "YOL043C", "Q08214", "YOL043C", "Q08214", "YOL043C" ] }, "reaction_10781214": { "compartment": "compartment_7660", "id": "reaction_10781214", "reactome": "R-SCE-5693540", "name": "MRN activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779175", "species_29358" ], "products": [ "species_113582", "species_10781211", "species_10768327" ], "modifiers": [ [ "species_10779175", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10764681": { "compartment": "compartment_7660", "id": "reaction_10764681", "reactome": "R-SCE-110215", "name": "Cleavage of uracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764674" ], "products": [ "species_29554", "species_10764678" ], "modifiers": [ [ "species_10764674", "catalyst" ] ], "additional_components": [ "P12887", "YML021C", "P12887", "YML021C", "P12887", "YML021C" ] }, "reaction_10777649": { "compartment": "compartment_7660", "id": "reaction_10777649", "reactome": "R-SCE-5358525", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358514", "species_10777645" ], "products": [ "species_10777647" ], "modifiers": [], "additional_components": [ "species_29370", "Q03834", "YDR097C", "P25847", "YOL090W", "species_29370", "Q03834", "YDR097C", "P25847", "YOL090W" ] }, "reaction_10777799": { "compartment": "compartment_7660", "id": "reaction_10777799", "reactome": "R-SCE-5444523", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777607", "species_10777602" ], "products": [ "species_10777609" ], "modifiers": [], "additional_components": [ "YNL082W", "YMR167W", "P14242", "YNL082W", "P38920", "YMR167W" ] }, "reaction_10779382": { "compartment": "compartment_7660", "id": "reaction_10779382", "reactome": "R-SCE-5683405", "name": "PPP5C dephosphorylates TP53BP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10779372" ], "products": [ "species_113550", "species_10779374" ], "modifiers": [ [ "species_10779379", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P14737", "YDR217C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P14737", "YDR217C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "YGR123C" ] }, "reaction_10781806": { "compartment": "compartment_7660", "id": "reaction_10781806", "reactome": "R-SCE-6782069", "name": "UVSSA:USP7 deubiquitinates ERCC6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781797", "species_113518" ], "products": [ "species_10781803", "species_10760537" ], "modifiers": [ [ "species_10781797", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10781850": { "compartment": "compartment_7660", "id": "reaction_10781850", "reactome": "R-SCE-6782208", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781845", "species_30555" ], "products": [ "species_10781847", "species_113541" ], "modifiers": [ [ "species_10781845", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P38251", "YBR087W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P38251", "YBR087W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P38251", "YBR087W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10777797": { "compartment": "compartment_7660", "id": "reaction_10777797", "reactome": "R-SCE-5444516", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10777619", "species_10777614" ], "products": [ "species_10777645" ], "modifiers": [], "additional_components": [ "YDR097C", "YOL090W", "species_29370", "Q03834", "YDR097C", "P25847", "YOL090W" ] }, "reaction_10777643": { "compartment": "compartment_7660", "id": "reaction_10777643", "reactome": "R-SCE-5358518", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777625" ], "products": [ "species_10777640" ], "modifiers": [ [ "species_10777625", "catalyst" ] ], "additional_components": [ "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W", "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W", "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W" ] }, "reaction_10789082": { "compartment": "compartment_7660", "id": "reaction_10789082", "reactome": "R-SCE-9684118", "name": "ERCC3-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781814" ], "products": [ "species_113582", "species_113550", "species_10781825" ], "modifiers": [ [ "species_10781814", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10779270": { "compartment": "compartment_7660", "id": "reaction_10779270", "reactome": "R-SCE-5682598", "name": "ATM phosphorylates HERC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779263" ], "products": [ "species_113582", "species_10779267" ], "modifiers": [ [ "species_10779263", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10777651": { "compartment": "compartment_7660", "id": "reaction_10777651", "reactome": "R-SCE-5358592", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358610", "species_29358" ], "products": [ "species_109966", "species_164121", "species_113541" ], "modifiers": [ [ "species_10760994", "catalyst" ] ], "additional_components": [ "YDL164C" ] }, "reaction_10778493": { "compartment": "compartment_7660", "id": "reaction_10778493", "reactome": "R-SCE-5655481", "name": "USP1:WDR48 binds monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778484", "species_10778482" ], "products": [ "species_10778486" ], "modifiers": [], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P36026", "YKR098C", "Q99247", "YOL087C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "P38630", "YOR217W", "P40339", "YOL094C", "Q99247", "YOL087C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P36026", "YKR098C", "P26754", "YNL312W", "P25037", "YDL122W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P39967", "YER098W", "P15873", "YBR088C", "P40453", "YIL156W", "P38187", "YBL067C" ] }, "reaction_10764688": { "compartment": "compartment_7660", "id": "reaction_10764688", "reactome": "R-SCE-110217", "name": "Cleavage of 5-hydroxyluracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764685" ], "products": [ "species_10764678", "species_110216" ], "modifiers": [ [ "species_10764685", "catalyst" ] ], "additional_components": [ "P12887", "YML021C", "P12887", "YML021C", "P12887", "YML021C" ] }, "reaction_10777996": { "compartment": "compartment_70101", "id": "reaction_10777996", "reactome": "R-SCE-5618331", "name": "HDAC6 deacetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_10777993" ], "products": [ "species_10768744", "species_76183" ], "modifiers": [ [ "species_10777457", "catalyst" ] ], "additional_components": [ "P09734", "YML124C", "species_29420", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "species_29420", "P09734", "YML124C", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "YNL021W" ] }, "reaction_10778225": { "compartment": "compartment_13949", "id": "reaction_10778225", "reactome": "R-SCE-5638014", "name": "RAB11A:GTP-containing Golgi vesicles recruit RAB3IP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778216", "species_10778221" ], "products": [ "species_10778223" ], "modifiers": [], "additional_components": [ "P51996", "YGL210W", "P38555", "YER031C", "species_29438", "YNL272C", "P51996", "YGL210W", "P38555", "YER031C", "species_29438", "P17065", "YNL272C" ] }, "reaction_10787471": { "compartment": "compartment_70616", "id": "reaction_10787471", "reactome": "R-SCE-8949580", "name": "F1Fo ATP synthase dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765816" ], "products": [ "species_10787469" ], "modifiers": [], "additional_components": [ "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W" ] }, "reaction_10761323": { "compartment": "compartment_70101", "id": "reaction_10761323", "reactome": "R-SCE-70475", "name": "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10761318", "catalyst" ] ], "additional_components": [ "P12709", "YBR196C" ] }, "reaction_10778180": { "compartment": "compartment_70101", "id": "reaction_10778180", "reactome": "R-SCE-5631885", "name": "PRDX1 overoxidizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29408", "species_10778172" ], "products": [ "species_29356", "species_10778177" ], "modifiers": [ [ "species_10778172", "catalyst" ] ], "additional_components": [ "P34760", "YML028W", "P34760", "YML028W", "P34760", "YML028W" ] }, "reaction_10762082": { "compartment": "compartment_70101", "id": "reaction_10762082", "reactome": "R-SCE-71682", "name": "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_111745" ], "products": [ "species_29366", "species_29450" ], "modifiers": [ [ "species_10762079", "catalyst" ] ], "additional_components": [ "P41921", "YPL091W", "species_113596" ] }, "reaction_10761172": { "compartment": "compartment_70101", "id": "reaction_10761172", "reactome": "R-SCE-70377", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_30537" ], "products": [ "species_70106", "species_29364", "species_31467" ], "modifiers": [ [ "species_10761169", "catalyst" ] ], "additional_components": [ "species_29366", "P11412", "YNL241C" ] }, "reaction_10771975": { "compartment": "compartment_20699", "id": "reaction_10771975", "reactome": "R-SCE-964737", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_915149" ], "products": [ "species_964740", "species_964752" ], "modifiers": [ [ "species_10771968", "catalyst" ] ], "additional_components": [ "YLR057W" ] }, "reaction_10777597": { "compartment": "compartment_70101", "id": "reaction_10777597", "reactome": "R-SCE-5358494", "name": "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777577", "species_71284" ], "products": [ "species_10777564", "species_353106" ], "modifiers": [ [ "species_10777594", "catalyst" ] ], "additional_components": [ "P32461", "YKL191W", "P40487", "YIL103W", "Q3E840", "YBL071W-A" ] }, "reaction_10769136": { "compartment": "compartment_70101", "id": "reaction_10769136", "reactome": "R-SCE-391266", "name": "Association of CCT/TriC with sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769132", "species_10769088" ], "products": [ "species_10769134" ], "modifiers": [], "additional_components": [ "P39079", "YDR188W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "YLR260W", "P39079", "YDR188W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "Q06147", "YLR260W" ] }, "reaction_10784720": { "compartment": "compartment_20699", "id": "reaction_10784720", "reactome": "R-SCE-6809015", "name": "NSF ATPase activity dissociates cis-SNARE at cis-Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10784715" ], "products": [ "species_10784697", "species_10784688", "species_10784699", "species_10784683", "species_29372", "species_10784703", "species_10784707" ], "modifiers": [ [ "species_10784715", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W", "P22804", "YIL004C", "P43682", "YKL006C-A", "YHL031C", "YLR026C", "YKL196C", "YLR078C", "YIL004C", "P25385", "YLR078C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W" ] }, "reaction_10776520": { "compartment": "compartment_12045", "id": "reaction_10776520", "reactome": "R-SCE-4419978", "name": "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4419987", "species_191362" ], "products": [ "species_4419982" ], "modifiers": [ [ "species_10776517", "catalyst" ] ], "additional_components": [ "Q12063", "YDL193W", "P35196", "YBR002C" ] }, "reaction_10765434": { "compartment": "compartment_70101", "id": "reaction_10765434", "reactome": "R-SCE-156930", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10765430" ], "products": [ "species_10765432" ], "modifiers": [], "additional_components": [ "P32324", "EFT2", "species_29438" ] }, "reaction_10774887": { "compartment": "compartment_7660", "id": "reaction_10774887", "reactome": "R-SCE-2997723", "name": "PIAS4 SUMOylates TP53BP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10774864" ], "products": [ "species_10774872", "species_10774805" ], "modifiers": [ [ "species_10774884", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDR217C", "Q12306", "YDR510W", "P14737", "YDR217C", "YDL064W", "Q04195", "YDR409W", "Q12216", "YOR156C" ] }, "reaction_10781067": { "compartment": "compartment_70101", "id": "reaction_10781067", "reactome": "R-SCE-5691431", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766135" ], "products": [ "species_10766133" ], "modifiers": [ [ "species_10760639", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YFR004W" ] }, "reaction_10786777": { "compartment": "compartment_70101", "id": "reaction_10786777", "reactome": "R-SCE-8870469", "name": "RGGT geranylgeranylates RAB proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786641", "species_1131164" ], "products": [ "species_10786772", "species_111294", "species_10786774" ], "modifiers": [ [ "species_10786641", "catalyst" ] ], "additional_components": [ "Q99260", "YLR262C", "species_1131164", "P32864", "YOR370C", "Q00618", "YJL031C", "P36017", "YOR089C", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P20133", "YPR176C", "P48559", "YNL304W", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "Q99260", "YLR262C", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P32864", "YOR370C", "P48559", "YNL304W", "P36017", "YOR089C", "species_1131164", "P20133", "YPR176C", "Q00618", "YJL031C", "Q99260", "YLR262C", "species_1131164", "P32864", "YOR370C", "Q00618", "YJL031C", "P36017", "YOR089C", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P20133", "YPR176C", "P48559", "YNL304W" ] }, "reaction_10787662": { "compartment": "compartment_17947", "id": "reaction_10787662", "reactome": "R-SCE-8953917", "name": "PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787654", "species_10787658" ], "products": [ "species_10787660" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "Q05568", "YDR265W", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "Q04370", "YMR026C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05568", "YDR265W" ] }, "reaction_10765525": { "compartment": "compartment_12045", "id": "reaction_10765525", "reactome": "R-SCE-162873", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855663", "species_449229" ], "products": [ "species_162872", "species_8855667" ], "modifiers": [ [ "species_10765522", "catalyst" ] ], "additional_components": [ "YBR004C" ] }, "reaction_10770358": { "compartment": "compartment_70101", "id": "reaction_10770358", "reactome": "R-SCE-446185", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449703" ], "products": [ "species_532204" ], "modifiers": [ [ "species_10770355", "catalyst" ] ], "additional_components": [ "YEL058W" ] }, "reaction_10768034": { "compartment": "compartment_70101", "id": "reaction_10768034", "reactome": "R-SCE-204662", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10767990", "species_29368" ], "products": [ "species_10768024", "species_29360", "species_29356" ], "modifiers": [ [ "species_10768031", "catalyst" ] ], "additional_components": [ "P19211", "YJR047C", "P23301", "YEL034W", "P19211", "YJR047C", "P23301", "YEL034W", "P47120", "YJR070C", "species_111793" ] }, "reaction_10787059": { "compartment": "compartment_7660", "id": "reaction_10787059", "reactome": "R-SCE-8932221", "name": "METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10775766" ], "products": [ "species_10787051", "species_77502" ], "modifiers": [ [ "species_10787056", "catalyst" ] ], "additional_components": [ "YLL024C", "YLL024C", "YNL024C" ] }, "reaction_10785932": { "compartment": "compartment_70101", "id": "reaction_10785932", "reactome": "R-SCE-8853529", "name": "OTULIN,USP5 cleaves UBB yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785930" ], "products": [ "species_10760584", "species_10760576", "species_10760568" ], "modifiers": [ [ "species_10780500", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YBR058C" ] }, "reaction_10776349": { "compartment": "compartment_7660", "id": "reaction_10776349", "reactome": "R-SCE-3900177", "name": "SUMOylation of DDX5 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776339" ], "products": [ "species_10774805", "species_10776347" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YNL112W", "YDL064W", "P24783", "YNL112W", "Q12306", "YDR510W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10772580": { "compartment": "compartment_70101", "id": "reaction_10772580", "reactome": "R-SCE-1022127", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772576" ], "products": [ "species_10772578" ], "modifiers": [], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "species_915149", "CHEBI:60627", "P05759", "RPS31", "species_964740", "CHEBI:60629", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "CHEBI:60628" ] }, "reaction_10770374": { "compartment": "compartment_17957", "id": "reaction_10770374", "reactome": "R-SCE-446189", "name": "Addition of a second glucose to the N-glycan precursor by ALG8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449649", "species_532542" ], "products": [ "species_449311", "species_449638" ], "modifiers": [ [ "species_10770371", "catalyst" ] ], "additional_components": [ "YOR067C" ] }, "reaction_10776364": { "compartment": "compartment_7660", "id": "reaction_10776364", "reactome": "R-SCE-3968362", "name": "SUMOylation of PIAS4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10774884" ], "products": [ "species_10776362", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "Q04195", "YDR409W", "Q12216", "YOR156C", "Q04195", "YDR409W", "Q12216", "YOR156C", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10781491": { "compartment": "compartment_6791047", "id": "reaction_10781491", "reactome": "R-SCE-5694425", "name": "NSF ATPase activity dissociates cis-SNARE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10781486" ], "products": [ "species_10781458", "species_10781451", "species_10769994", "species_10781444", "species_10781474", "species_10781482", "species_29372", "species_10781453" ], "modifiers": [ [ "species_10781486", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P22804", "YIL004C", "P22213", "YDR189W", "P36015", "YKL196C", "P32854", "YOR036W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W", "YDR189W", "YIL004C", "YBL050W", "P18759", "YBR080C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P32854", "YOR036W", "P36015", "YKL196C", "P22214", "YLR268W", "YLR078C", "P25385", "YLR078C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P22804", "YIL004C", "P22213", "YDR189W", "P36015", "YKL196C", "P32854", "YOR036W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W" ] }, "reaction_10776337": { "compartment": "compartment_7660", "id": "reaction_10776337", "reactome": "R-SCE-3900047", "name": "SUMOylation of DDX17 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776327", "species_10774813" ], "products": [ "species_10776335", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "YNL112W", "P50623", "YDL064W", "Q12306", "YDR510W", "P24783", "YNL112W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10785870": { "compartment": "compartment_70101", "id": "reaction_10785870", "reactome": "R-SCE-8852134", "name": "UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760634", "species_113592", "species_10772385" ], "products": [ "species_111294", "species_10785770" ], "modifiers": [ [ "species_10772385", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YKL210W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YKL210W" ] }, "reaction_10768010": { "compartment": "compartment_70101", "id": "reaction_10768010", "reactome": "R-SCE-204617", "name": "DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10767990", "species_204628" ], "products": [ "species_29360", "species_204635", "species_10768000" ], "modifiers": [ [ "species_10768007", "catalyst" ] ], "additional_components": [ "P19211", "YJR047C", "P23301", "YEL034W", "P19211", "YJR047C", "P23301", "YEL034W", "P38791", "YHR068W" ] }, "reaction_10770366": { "compartment": "compartment_17957", "id": "reaction_10770366", "reactome": "R-SCE-446188", "name": "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449298", "species_449229" ], "products": [ "species_449311", "species_449315" ], "modifiers": [ [ "species_10770363", "catalyst" ] ], "additional_components": [ "YBL082C" ] }, "reaction_10762154": { "compartment": "compartment_70101", "id": "reaction_10762154", "reactome": "R-SCE-71732", "name": "PPA1 hydrolyzes pyrophosphate to orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294", "species_29356" ], "products": [ "species_29372" ], "modifiers": [ [ "species_10762151", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P28239", "YMR267W", "P00817", "YBR011C" ] }, "reaction_10763035": { "compartment": "compartment_70101", "id": "reaction_10763035", "reactome": "R-SCE-72671", "name": "eIF5B:GTP is hydrolyzed and released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763029" ], "products": [ "species_10763031", "species_10763033", "species_29372" ], "modifiers": [], "additional_components": [ "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "P39730", "YAL035W", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B", "species_29420", "P39730", "YAL035W", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B" ] }, "reaction_10774923": { "compartment": "compartment_7660", "id": "reaction_10774923", "reactome": "R-SCE-3000434", "name": "PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774893", "species_10774813" ], "products": [ "species_10774805", "species_10774906" ], "modifiers": [ [ "species_10774920", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "Q12306", "YDR510W", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q04195", "YDR409W", "Q12216", "YOR156C" ] }, "reaction_10785859": { "compartment": "compartment_7660", "id": "reaction_10785859", "reactome": "R-SCE-8852130", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785838", "species_10785824" ], "products": [ "species_10785686", "species_10785857" ], "modifiers": [], "additional_components": [ "P52492", "YOR339C", "P15731", "YBR082C", "P15732", "YDR059C", "P06104", "YGL058W", "P14682", "YDR054C", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52492", "YOR339C", "P15731", "YBR082C", "P05759", "RPS31", "P15732", "YDR059C", "P06104", "YGL058W", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10787096": { "compartment": "compartment_70101", "id": "reaction_10787096", "reactome": "R-SCE-8932413", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10765400" ], "products": [ "species_71285", "species_10787088" ], "modifiers": [ [ "species_10787093", "catalyst" ] ], "additional_components": [ "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "YIL064W" ] }, "reaction_10776706": { "compartment": "compartment_7660", "id": "reaction_10776706", "reactome": "R-SCE-4641342", "name": "SUMOylation of TOP2A with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776696", "species_10774813" ], "products": [ "species_10776704", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "YNL088W", "P50623", "YDL064W", "Q12306", "YDR510W", "P06786", "YNL088W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10777327": { "compartment": "compartment_7660", "id": "reaction_10777327", "reactome": "R-SCE-5228523", "name": "RANBP2 SUMOylates MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774893", "species_10774813" ], "products": [ "species_10774805", "species_10774906" ], "modifiers": [ [ "species_10763942", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "Q12306", "YDR510W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P40066", "YER107C", "Q02455", "YKR095W", "P36161", "YKR082W", "P52891", "YDL116W", "P38181", "YBL079W", "P53011", "YGL100W", "P20676", "YOR098C", "P47054", "YJL039C", "Q02630", "YMR047C", "P40368", "YJL061W", "Q04491", "YLR208W", "Q05166", "YDL088C", "P46673", "YJR042W", "P48837", "YGR119C", "P34077", "YFR002W", "P14907", "YJL041W", "P52593", "YML103C", "P35729", "YKL057C", "P32500", "YML031W", "P41920", "YDR002W" ] }, "reaction_10776585": { "compartment": "compartment_7660", "id": "reaction_10776585", "reactome": "R-SCE-4570467", "name": "SUMOylation of NOP58 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776574" ], "products": [ "species_10774805", "species_10776583" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "Q12306", "YDR510W", "Q12499", "NOP58", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10784643": { "compartment": "compartment_6791047", "id": "reaction_10784643", "reactome": "R-SCE-6807877", "name": "ARFGAPs stimulate ARF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784546" ], "products": [ "species_10784367", "species_10784640", "species_10784463", "species_10784385" ], "modifiers": [ [ "species_10784546", "catalyst" ] ], "additional_components": [ "P32803", "YGL200C", "P25386", "YDL058W", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "P22804", "YIL004C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P36015", "YKL196C", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P32803", "YGL200C", "P25386", "YDL058W", "P53198", "YGL002W", "P22804", "YIL004C", "P39704", "YAL007C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P43621", "YFR051C", "P53600", "YPL010W", "P01123", "YFL038C", "P53622", "YDL145C", "Q12403", "YDL018C", "P40509", "YIL076W", "P36015", "YKL196C", "P32074", "YNL287W", "P41811", "YGL137W", "P32572", "YNL204C", "P38682", "YER122C", "P35197", "YDL226C", "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "P32803", "YGL200C", "P25386", "YDL058W", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "P22804", "YIL004C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P36015", "YKL196C", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C" ] }, "reaction_10770382": { "compartment": "compartment_12045", "id": "reaction_10770382", "reactome": "R-SCE-446191", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449299", "species_162756" ], "products": [ "species_109402", "species_449222" ], "modifiers": [ [ "species_10770379", "catalyst" ] ], "additional_components": [ "YBR243C" ] }, "reaction_10776642": { "compartment": "compartment_7660", "id": "reaction_10776642", "reactome": "R-SCE-4615872", "name": "RANBP2 SUMOylates HDAC4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776632" ], "products": [ "species_10776640", "species_10774805" ], "modifiers": [ [ "species_10763942", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YNL021W", "Q12306", "YDR510W", "P53973", "YNL021W", "YDL064W", "P40066", "YER107C", "Q02455", "YKR095W", "P36161", "YKR082W", "P52891", "YDL116W", "P38181", "YBL079W", "P53011", "YGL100W", "P20676", "YOR098C", "P47054", "YJL039C", "Q02630", "YMR047C", "P40368", "YJL061W", "Q04491", "YLR208W", "Q05166", "YDL088C", "P46673", "YJR042W", "P48837", "YGR119C", "P34077", "YFR002W", "P14907", "YJL041W", "P52593", "YML103C", "P35729", "YKL057C", "P32500", "YML031W", "P41920", "YDR002W" ] }, "reaction_10765517": { "compartment": "compartment_70101", "id": "reaction_10765517", "reactome": "R-SCE-162857", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855657", "species_29356" ], "products": [ "species_29416", "species_8855661" ], "modifiers": [ [ "species_10765514", "catalyst" ] ], "additional_components": [ "YMR281W" ] }, "reaction_10770615": { "compartment": "compartment_5460", "id": "reaction_10770615", "reactome": "R-SCE-449937", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_159450" ], "products": [ "species_113548" ], "modifiers": [ [ "species_10770612", "catalyst" ], [ "species_109496", "catalyst" ] ], "additional_components": [ "P00817", "YBR011C" ] }, "reaction_10765380": { "compartment": "compartment_70101", "id": "reaction_10765380", "reactome": "R-SCE-156823", "name": "Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765355", "species_10765376" ], "products": [ "species_10765378" ], "modifiers": [], "additional_components": [ "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38760", "YHR015W", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "P04147", "YER165W", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P39684", "YFR023W", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38760", "YHR015W", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "P04147", "YER165W", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P39684", "YFR023W", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P26784", "RPL16A", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C" ] }, "reaction_10776408": { "compartment": "compartment_7660", "id": "reaction_10776408", "reactome": "R-SCE-4085350", "name": "SUMOylation of UBE2I with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10774805" ], "products": [ "species_10776406", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10787608": { "compartment": "compartment_70101", "id": "reaction_10787608", "reactome": "R-SCE-8952618", "name": "AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787593" ], "products": [ "species_10787605", "species_10787548" ], "modifiers": [ [ "species_10787593", "catalyst" ] ], "additional_components": [ "Q12395", "YLR128W", "P13365", "YAL040C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P24868", "YGR108W", "Q04511", "YML088W", "P20438", "YPL256C", "P32943", "YGR109C", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P52491", "YLR306W", "P36037", "YKL213C", "Q12347", "YLR097C", "Q03919", "YDR139C", "Q12395", "YLR128W", "P13365", "YAL040C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P24868", "YGR108W", "Q04511", "YML088W", "P20438", "YPL256C", "P32943", "YGR109C", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03919", "YDR139C", "P36037", "YKL213C", "Q12347", "YLR097C", "YLR306W", "Q12395", "YLR128W", "P13365", "YAL040C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P24868", "YGR108W", "Q04511", "YML088W", "P20438", "YPL256C", "P32943", "YGR109C", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P52491", "YLR306W", "P36037", "YKL213C", "Q12347", "YLR097C", "Q03919", "YDR139C" ] }, "reaction_10773656": { "compartment": "compartment_70101", "id": "reaction_10773656", "reactome": "R-SCE-1799332", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773652", "species_10773650" ], "products": [ "species_10773654" ], "modifiers": [], "additional_components": [ "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B", "P38687", "YPL243W", "P32342", "YKL122C", "P38688", "YPL210C", "P29478", "YML105C", "P38985", "YDL092W", "P20424", "YPR088C", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29478", "YML105C", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P20424", "YPR088C", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P38687", "YPL243W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P32342", "YKL122C", "P38688", "YPL210C", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "P38985", "YDL092W", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B" ] }, "reaction_10777561": { "compartment": "compartment_70101", "id": "reaction_10777561", "reactome": "R-SCE-5358475", "name": "DPH6 ligates ammonium to diphthine-EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_31633", "species_10777553" ], "products": [ "species_10765430", "species_111294", "species_76577" ], "modifiers": [ [ "species_10777558", "catalyst" ] ], "additional_components": [ "YLR143W" ] }, "reaction_10786576": { "compartment": "compartment_70101", "id": "reaction_10786576", "reactome": "R-SCE-8870465", "name": "RGGT binds the RAB-binding subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786568", "species_10784093", "species_1131164" ], "products": [ "species_10786574" ], "modifiers": [], "additional_components": [ "P20133", "YPR176C", "Q00618", "YJL031C", "YOR370C", "species_1131164", "P32864", "YOR370C", "P20133", "YPR176C", "Q00618", "YJL031C" ] }, "reaction_10775215": { "compartment": "compartment_7660", "id": "reaction_10775215", "reactome": "R-SCE-3232162", "name": "PIAS3 SUMOylates MITF with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10775197" ], "products": [ "species_10774805", "species_10775206" ], "modifiers": [ [ "species_10775212", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YBL103C", "YDL064W", "P38165", "YBL103C", "Q12306", "YDR510W", "Q04195", "YDR409W", "Q12216", "YOR156C" ] }, "reaction_10762699": { "compartment": "compartment_70101", "id": "reaction_10762699", "reactome": "R-SCE-72663", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10762638" ], "products": [ "species_10762640" ], "modifiers": [], "additional_components": [ "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438" ] }, "reaction_10787672": { "compartment": "compartment_17947", "id": "reaction_10787672", "reactome": "R-SCE-8953946", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787660" ], "products": [ "species_10772640", "species_10787669" ], "modifiers": [ [ "species_10787660", "catalyst" ] ], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "Q04370", "YMR026C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05568", "YDR265W", "P15731", "YBR082C", "P15732", "YDR059C", "P35056", "phospho-PEX5", "P53112", "PEX14", "P05759", "RPS31", "P80667", "PEX13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q04370", "YMR026C", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "Q04370", "YMR026C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05568", "YDR265W" ] }, "reaction_10770406": { "compartment": "compartment_12045", "id": "reaction_10770406", "reactome": "R-SCE-446200", "name": "DOLPP1 dephosphorylates DOLDP to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449744", "species_29356" ], "products": [ "species_449299", "species_29372" ], "modifiers": [ [ "species_10770403", "catalyst" ] ], "additional_components": [ "YGR036C" ] }, "reaction_10762732": { "compartment": "compartment_70101", "id": "reaction_10762732", "reactome": "R-SCE-72670", "name": "Formation of eIF2:GDP:eIF2B intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762728", "species_10762689" ], "products": [ "species_10762730" ], "modifiers": [], "additional_components": [ "P09032", "YOR260W", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P32501", "YDR211W", "species_29420", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "P09032", "YOR260W", "species_29420", "P32481", "GCD11", "P09064", "SUI3", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P20459", "phospho-SUI2", "P32501", "YDR211W" ] }, "reaction_10776691": { "compartment": "compartment_7660", "id": "reaction_10776691", "reactome": "R-SCE-4616015", "name": "SUMOylation of HDAC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776117", "species_10774813" ], "products": [ "species_10776689", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "YPR068C", "P50623", "YDL064W", "Q12306", "YDR510W", "Q12306", "YDR510W", "Q12214", "YPR068C", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10785332": { "compartment": "compartment_6791047", "id": "reaction_10785332", "reactome": "R-SCE-6814831", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781520", "species_10785328" ], "products": [ "species_10785330" ], "modifiers": [], "additional_components": [ "P01123", "YFL038C", "species_29438", "YFL027C", "P01123", "YFL038C", "species_29438", "P43570", "YFL027C" ] }, "reaction_10770593": { "compartment": "compartment_70101", "id": "reaction_10770593", "reactome": "R-SCE-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29512" ], "products": [ "species_29404", "species_449701" ], "modifiers": [ [ "species_10770590", "catalyst" ] ], "additional_components": [ "P14742", "YKL104C", "P0CF18", "YMR085W" ] }, "reaction_10776528": { "compartment": "compartment_12045", "id": "reaction_10776528", "reactome": "R-SCE-4419979", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_4419981" ], "products": [ "species_29366", "species_449221" ], "modifiers": [ [ "species_10776525", "catalyst" ] ], "additional_components": [ "YIL049W" ] }, "reaction_10785861": { "compartment": "compartment_7660", "id": "reaction_10785861", "reactome": "R-SCE-8852131", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10785822", "species_10760537" ], "products": [ "species_113541", "species_10785824" ], "modifiers": [], "additional_components": [ "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10763043": { "compartment": "compartment_70101", "id": "reaction_10763043", "reactome": "R-SCE-72691", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763041", "species_10762642" ], "products": [ "species_10762644" ], "modifiers": [], "additional_components": [ "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P40217", "YMR146C", "P0CX32", "RPS24B", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C" ] }, "reaction_10776600": { "compartment": "compartment_7660", "id": "reaction_10776600", "reactome": "R-SCE-4570493", "name": "RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776590", "species_10774813" ], "products": [ "species_10776598", "species_10774805" ], "modifiers": [ [ "species_10763942", "catalyst" ] ], "additional_components": [ "YPL190C", "P50623", "YDL064W", "Q12306", "YDR510W", "P38996", "YPL190C", "Q12306", "YDR510W", "YDL064W", "P40066", "YER107C", "Q02455", "YKR095W", "P36161", "YKR082W", "P52891", "YDL116W", "P38181", "YBL079W", "P53011", "YGL100W", "P20676", "YOR098C", "P47054", "YJL039C", "Q02630", "YMR047C", "P40368", "YJL061W", "Q04491", "YLR208W", "Q05166", "YDL088C", "P46673", "YJR042W", "P48837", "YGR119C", "P34077", "YFR002W", "P14907", "YJL041W", "P52593", "YML103C", "P35729", "YKL057C", "P32500", "YML031W", "P41920", "YDR002W" ] }, "reaction_10770224": { "compartment": "compartment_1462052", "id": "reaction_10770224", "reactome": "R-SCE-437085", "name": "ZnT5 transports zinc into secretory granules in pancreatic beta cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10770221", "catalyst" ] ], "additional_components": [ "YDR205W" ] }, "reaction_10770603": { "compartment": "compartment_70101", "id": "reaction_10770603", "reactome": "R-SCE-449734", "name": "Acetylation of glucosamine 6-phosphate to GlcNAc6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449701", "species_76183" ], "products": [ "species_76194", "species_449703" ], "modifiers": [ [ "species_10770600", "catalyst" ] ], "additional_components": [ "P43577", "YFL017C" ] }, "reaction_10786570": { "compartment": "compartment_70101", "id": "reaction_10786570", "reactome": "R-SCE-8870461", "name": "RABGGTA and RABGGTB bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786564", "species_10786566" ], "products": [ "species_10786568" ], "modifiers": [], "additional_components": [ "YJL031C", "YPR176C", "P20133", "YPR176C", "Q00618", "YJL031C" ] }, "reaction_10762701": { "compartment": "compartment_70101", "id": "reaction_10762701", "reactome": "R-SCE-72669", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762640", "species_72393" ], "products": [ "species_10762642" ], "modifiers": [ [ "species_29438", "catalyst" ] ], "additional_components": [ "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438" ] }, "reaction_10781400": { "compartment": "compartment_13959", "id": "reaction_10781400", "reactome": "R-SCE-5694409", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10781393" ], "products": [ "species_10781397", "species_29420" ], "modifiers": [ [ "species_10781393", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "species_29420", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P40482", "YIL109C", "P01123", "YFL038C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C", "P25385", "YLR078C", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "species_29438", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P01123", "YFL038C", "P40482", "YIL109C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C", "P25385", "YLR078C", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "species_29420", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P40482", "YIL109C", "P01123", "YFL038C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C" ] }, "reaction_10776398": { "compartment": "compartment_7660", "id": "reaction_10776398", "reactome": "R-SCE-3968414", "name": "UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776376" ], "products": [ "species_10774805", "species_10776393" ], "modifiers": [ [ "species_10776395", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "P25364", "YCR065W", "P40466", "YIL131C", "YDL064W", "Q12306", "YDR510W", "P25364", "YCR065W", "P40466", "YIL131C", "Q04195", "YDR409W", "Q12216", "YOR156C", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10770449": { "compartment": "compartment_12045", "id": "reaction_10770449", "reactome": "R-SCE-446214", "name": "Synthesis of dolichyl-phosphate-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_449299" ], "products": [ "species_110096", "species_532214" ], "modifiers": [ [ "species_10770446", "catalyst" ] ], "additional_components": [ "YPL227C" ] }, "reaction_10785688": { "compartment": "compartment_7660", "id": "reaction_10785688", "reactome": "R-SCE-8852128", "name": "UBA1 adenylates ubiquitin in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10785583", "species_10760537" ], "products": [ "species_10785686", "species_113541" ], "modifiers": [], "additional_components": [ "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10771977": { "compartment": "compartment_20699", "id": "reaction_10771977", "reactome": "R-SCE-964825", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964831" ], "products": [ "species_964740", "species_964752" ], "modifiers": [ [ "species_10771968", "catalyst" ] ], "additional_components": [ "CHEBI:60627", "CHEBI:60629", "CHEBI:60628", "YLR057W" ] }, "reaction_10774770": { "compartment": "compartment_7660", "id": "reaction_10774770", "reactome": "R-SCE-2990840", "name": "SENP1,2,5 proteolytically process SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774758" ], "products": [ "species_10774743" ], "modifiers": [ [ "species_10774763", "catalyst" ] ], "additional_components": [ "YDR510W", "YDR510W", "YPL020C" ] }, "reaction_10776472": { "compartment": "compartment_7660", "id": "reaction_10776472", "reactome": "R-SCE-4090284", "name": "SUMOylation of HIPK2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776462" ], "products": [ "species_10776470", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YJL141C", "P14680", "YJL141C", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10782019": { "compartment": "compartment_12045", "id": "reaction_10782019", "reactome": "R-SCE-6788650", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788753", "species_71284" ], "products": [ "species_6788758", "species_71285" ], "modifiers": [ [ "species_10782016", "catalyst" ] ], "additional_components": [ "species_158417", "P32584", "YDR410C" ] }, "reaction_10785820": { "compartment": "compartment_70101", "id": "reaction_10785820", "reactome": "R-SCE-8852129", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785690", "species_10785768" ], "products": [ "species_10785818", "species_10785770" ], "modifiers": [], "additional_components": [ "P52492", "YOR339C", "P15731", "YBR082C", "P15732", "YDR059C", "P14682", "YDR054C", "P28263", "YEL012W", "Q02159", "YMR022W", "P21734", "YDR177W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52492", "YOR339C", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P28263", "YEL012W", "Q02159", "YMR022W", "P21734", "YDR177W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10770457": { "compartment": "compartment_17957", "id": "reaction_10770457", "reactome": "R-SCE-446215", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449315", "species_449229" ], "products": [ "species_449311", "species_449312" ], "modifiers": [ [ "species_10770454", "catalyst" ] ], "additional_components": [ "YNL219C" ] }, "reaction_10787521": { "compartment": "compartment_70101", "id": "reaction_10787521", "reactome": "R-SCE-8951644", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781029" ], "products": [ "species_10781027", "species_10780910" ], "modifiers": [], "additional_components": [ "P35127", "YJR099W", "Q03919", "YDR139C", "YDR139C", "YJR099W" ] }, "reaction_10770459": { "compartment": "compartment_17957", "id": "reaction_10770459", "reactome": "R-SCE-446216", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449365" ], "products": [ "species_449311", "species_449371" ], "modifiers": [ [ "species_10770454", "catalyst" ] ], "additional_components": [ "YNL219C" ] }, "reaction_10765384": { "compartment": "compartment_70101", "id": "reaction_10765384", "reactome": "R-SCE-156826", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763018" ], "products": [ "species_10765382", "species_10762778" ], "modifiers": [], "additional_components": [ "P05748", "RPL15A", "P10622", "YDL130W", "P0CX83", "RPL19B", "P26321", "RPL5", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX23", "RPL20A", "P0CX54", "RPL12B", "P51401", "RPL9B", "P14126", "RPL3", "P0CX46", "RPL2B", "P0CH08", "RPL40A", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0CX42", "RPL23B", "P53221", "RPL26B", "P10664", "RPL4A", "P05740", "RPL17A", "P0CX27", "RPL42A", "P0CX44", "RPL1B", "P0CX28", "RPL42B", "P54780", "RPL15B", "P05744", "RPL33A", "P05759", "RPS31", "P02406", "RPL28", "P0CH09", "RPL40B", "P0C0W9", "RPL11A", "P04449", "RPL24A", "P0CX50", "RPL18B", "P41805", "RPL10", "P38061", "RPL32", "P0CX49", "RPL18A", "P0CX45", "RPL2A", "P14120", "RPL30", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P0CX43", "RPL1A", "P49166", "RPL37A", "P0CX53", "RPL12A", "P05749", "RPL22A", "P0CX82", "RPL19A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q3E757", "RPL11B", "P02400", "RPP2B", "P49626", "RPL4B", "P51402", "RPL37B", "P05743", "RPL26A", "P0C2H9", "RPL31B", "P05739", "RPL6B", "P05748", "RPL15A", "P10622", "YDL130W", "P0CX83", "RPL19B", "P26321", "RPL5", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX23", "RPL20A", "P0CX54", "RPL12B", "P51401", "RPL9B", "P14126", "RPL3", "P0CX46", "RPL2B", "P0CH08", "RPL40A", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0CX42", "RPL23B", "P53221", "RPL26B", "P10664", "RPL4A", "P05740", "RPL17A", "P0CX27", "RPL42A", "P0CX44", "RPL1B", "P0CX28", "RPL42B", "P54780", "RPL15B", "P05744", "RPL33A", "P05759", "RPS31", "P02406", "RPL28", "P0CH09", "RPL40B", "P0C0W9", "RPL11A", "P04449", "RPL24A", "P0CX50", "RPL18B", "P41805", "RPL10", "P38061", "RPL32", "P0CX49", "RPL18A", "P0CX45", "RPL2A", "P14120", "RPL30", "P05737", "RPL7A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P0CX43", "RPL1A", "P49166", "RPL37A", "P0CX53", "RPL12A", "P05749", "RPL22A", "P0CX82", "RPL19A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q3E757", "RPL11B", "P02400", "RPP2B", "P49626", "RPL4B", "P51402", "RPL37B", "P05743", "RPL26A", "P0C2H9", "RPL31B", "P05739", "RPL6B" ] }, "reaction_10784442": { "compartment": "compartment_6791047", "id": "reaction_10784442", "reactome": "R-SCE-6807872", "name": "Active ARF recruits coatomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784438", "species_10784393" ], "products": [ "species_10784440" ], "modifiers": [], "additional_components": [ "P43621", "YFR051C", "P53600", "YPL010W", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P41810", "YDR238C", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P41810", "YDR238C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W" ] }, "reaction_10781493": { "compartment": "compartment_13959", "id": "reaction_10781493", "reactome": "R-SCE-5694439", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781391", "species_10781345", "species_10767942" ], "products": [ "species_10781393" ], "modifiers": [], "additional_components": [ "P38334", "YBR254C", "Q03630", "YML077W", "Q03784", "YDR246W", "P36149", "YKR068C", "Q04183", "YDR407C", "Q03337", "YDR472W", "Q03660", "YMR218C", "Q99394", "YOR115C", "species_29420", "P01123", "YFL038C", "P25385", "YLR078C", "Q01590", "YLR026C", "Q04491", "YLR208W", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "Q12204", "YOR022C", "P36015", "YKL196C", "P15303", "YPR181C", "P22214", "YLR268W", "P38968", "YDL195W", "P25385", "YLR078C", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "species_29420", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P40482", "YIL109C", "P01123", "YFL038C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C" ] }, "reaction_10763039": { "compartment": "compartment_70101", "id": "reaction_10763039", "reactome": "R-SCE-72673", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762624", "species_10763020" ], "products": [ "species_10762624", "species_10762573", "species_10763018" ], "modifiers": [], "additional_components": [ "YMR260C", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B", "YMR260C", "P0CX52", "RPS16B", "P35997", "RPS27A", "Q08745", "RPS10A", "P46784", "RPS10B", "P25443", "RPS2", "P06367", "RPS14A", "P0CX55", "RPS18A", "P0CX32", "RPS24B", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX35", "RPS4A", "P23248", "RPS1B", "P0CH08", "RPL40A", "P0CX47", "RPS11A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "P0CX37", "RPS6A", "P0CX56", "RPS18B", "P38711", "RPS27B", "P26786", "RPS7A", "P0CX30", "RPS23B", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P07281", "RPS19B", "P05759", "RPS31", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P05748", "RPL15A", "P10622", "YDL130W", "P0CX83", "RPL19B", "P26321", "RPL5", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX23", "RPL20A", "P0CX54", "RPL12B", "P51401", "RPL9B", "P14126", "RPL3", "P0CX46", "RPL2B", "P0CH08", "RPL40A", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0CX42", "RPL23B", "P53221", "RPL26B", "P10664", "RPL4A", "P05740", "RPL17A", "P0CX27", "RPL42A", "P0CX44", "RPL1B", "P0CX28", "RPL42B", "P54780", "RPL15B", "P05744", "RPL33A", "P05759", "RPS31", "P02406", "RPL28", "P0CH09", "RPL40B", "P0C0W9", "RPL11A", "P04449", "RPL24A", "P0CX50", "RPL18B", "P41805", "RPL10", "P38061", "RPL32", "P0CX49", "RPL18A", "P0CX45", "RPL2A", "P14120", "RPL30", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P0CX43", "RPL1A", "P49166", "RPL37A", "P0CX53", "RPL12A", "P05749", "RPL22A", "P0CX82", "RPL19A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q3E757", "RPL11B", "P02400", "RPP2B", "P49626", "RPL4B", "P51402", "RPL37B", "P05743", "RPL26A", "P0C2H9", "RPL31B", "P05739", "RPL6B" ] }, "reaction_10781528": { "compartment": "compartment_6791047", "id": "reaction_10781528", "reactome": "R-SCE-5694441", "name": "CSNK1D phosphorylates SEC23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10781508" ], "products": [ "species_29370", "species_10781391", "species_10781520", "species_10781512", "species_10781437", "species_10767811", "species_10781514" ], "modifiers": [ [ "species_10781525", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "P25386", "YDL058W", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "species_29438", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P01123", "YFL038C", "P40482", "YIL109C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C", "Q04410", "YDR517W", "P38334", "YBR254C", "Q03630", "YML077W", "Q03784", "YDR246W", "P36149", "YKR068C", "Q04183", "YDR407C", "Q03337", "YDR472W", "Q03660", "YMR218C", "Q99394", "YOR115C", "P01123", "YFL038C", "species_29438", "YPR181C", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "Q04491", "YLR208W", "Q12204", "YOR022C", "P38968", "YDL195W", "P25385", "YLR078C", "Q01590", "YLR026C", "P25386", "YDL058W", "P38810", "YHR098C", "P36015", "YKL196C", "P15303", "YPR181C", "P22214", "YLR268W", "Q04410", "YDR517W", "YPL204W" ] }, "reaction_10765493": { "compartment": "compartment_12045", "id": "reaction_10765493", "reactome": "R-SCE-162797", "name": "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855656", "species_449229" ], "products": [ "species_8855664" ], "modifiers": [ [ "species_10765490", "catalyst" ] ], "additional_components": [ "YOR149C" ] }, "reaction_10770398": { "compartment": "compartment_17957", "id": "reaction_10770398", "reactome": "R-SCE-446198", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449312", "species_449229" ], "products": [ "species_449311", "species_449365" ], "modifiers": [ [ "species_10770395", "catalyst" ] ], "additional_components": [ "YNR030W" ] }, "reaction_10765509": { "compartment": "compartment_12045", "id": "reaction_10765509", "reactome": "R-SCE-162821", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855667", "species_449229" ], "products": [ "species_8855656", "species_162872" ], "modifiers": [ [ "species_10765506", "catalyst" ] ], "additional_components": [ "YGL142C" ] }, "reaction_10785872": { "compartment": "compartment_7660", "id": "reaction_10785872", "reactome": "R-SCE-8852136", "name": "UBA1 conjugates ubiquitin to UBA1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785686" ], "products": [ "species_10785822", "species_164121" ], "modifiers": [], "additional_components": [ "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10781420": { "compartment": "compartment_12045", "id": "reaction_10781420", "reactome": "R-SCE-5694415", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767888", "species_10781416", "species_10767816" ], "products": [ "species_10781418" ], "modifiers": [], "additional_components": [ "YPR181C", "P53953", "YNL049C", "P40482", "YIL109C", "YLR268W", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "P22214", "YLR268W" ] }, "reaction_10787561": { "compartment": "compartment_70101", "id": "reaction_10787561", "reactome": "R-SCE-8951661", "name": "Transfer of NEDD8 to AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787550" ], "products": [ "species_10787558", "species_10787538" ], "modifiers": [ [ "species_10787550", "catalyst" ] ], "additional_components": [ "Q12059", "YPL003W", "Q99344", "YPR066W", "P52491", "YLR306W", "Q03919", "YDR139C", "P52491", "YLR306W", "Q03919", "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "P52491", "YLR306W", "Q03919", "YDR139C" ] }, "reaction_10785864": { "compartment": "compartment_70101", "id": "reaction_10785864", "reactome": "R-SCE-8852132", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785692", "species_113592", "species_10760634" ], "products": [ "species_111294", "species_10785768" ], "modifiers": [ [ "species_10785692", "catalyst" ] ], "additional_components": [ "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10762691": { "compartment": "compartment_70101", "id": "reaction_10762691", "reactome": "R-SCE-72621", "name": "Ribosomal scanning ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762680", "species_113592" ], "products": [ "species_29370", "species_10762680", "species_29372" ], "modifiers": [ [ "species_72617", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C" ] }, "reaction_10787567": { "compartment": "compartment_70101", "id": "reaction_10787567", "reactome": "R-SCE-8951751", "name": "Doubly neddylated UBA3:NAE1 binds AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787543", "species_10787548" ], "products": [ "species_10787550" ], "modifiers": [], "additional_components": [ "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C", "YLR306W", "Q12059", "YPL003W", "Q99344", "YPR066W", "P52491", "YLR306W", "Q03919", "YDR139C" ] }, "reaction_10786643": { "compartment": "compartment_70101", "id": "reaction_10786643", "reactome": "R-SCE-8870466", "name": "RGGT:CHM binds RABs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786574", "species_10786639" ], "products": [ "species_10786641" ], "modifiers": [], "additional_components": [ "species_1131164", "P32864", "YOR370C", "P20133", "YPR176C", "Q00618", "YJL031C", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "Q99260", "YLR262C", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P48559", "YNL304W", "P36017", "YOR089C", "Q99260", "YLR262C", "species_1131164", "P32864", "YOR370C", "Q00618", "YJL031C", "P36017", "YOR089C", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P20133", "YPR176C", "P48559", "YNL304W" ] }, "reaction_10776610": { "compartment": "compartment_7660", "id": "reaction_10776610", "reactome": "R-SCE-4570496", "name": "SUMOylation of Histone H4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10763701" ], "products": [ "species_10774805", "species_10776608" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YBR009C", "YDL064W", "P02309", "YBR009C", "Q12306", "YDR510W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10771137": { "compartment": "compartment_70101", "id": "reaction_10771137", "reactome": "R-SCE-532549", "name": "MPI isomerises Fru6P to Man6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_532562" ], "modifiers": [ [ "species_10771134", "catalyst" ] ], "additional_components": [ "YER003C" ] }, "reaction_10784375": { "compartment": "compartment_6791047", "id": "reaction_10784375", "reactome": "R-SCE-6807864", "name": "RAB1:GTP recruits GBF1 to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781520", "species_10784367", "species_10784371" ], "products": [ "species_10784373" ], "modifiers": [], "additional_components": [ "P01123", "YFL038C", "species_29438", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P25386", "YDL058W", "P47102", "YJR031C", "P25386", "YDL058W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "species_29438" ] }, "reaction_10785905": { "compartment": "compartment_70101", "id": "reaction_10785905", "reactome": "R-SCE-8853503", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760568" ], "products": [ "species_10762487", "species_10760568" ], "modifiers": [ [ "species_10785902", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P50101", "YMR304W", "P35127", "YJR099W" ] }, "reaction_10775006": { "compartment": "compartment_7660", "id": "reaction_10775006", "reactome": "R-SCE-3108212", "name": "SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10774426" ], "products": [ "species_10774805", "species_10774972" ], "modifiers": [ [ "species_10775003", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "P32908", "YFL008W", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "YDL064W", "P32908", "YFL008W", "Q12306", "YDR510W", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "P43124", "YDL105W", "Q12749", "YLR383W", "Q05541", "YDR288W", "P38632", "YEL019C", "Q07913", "YLR007W", "Q08204", "YOL034W" ] }, "reaction_10781488": { "compartment": "compartment_6791047", "id": "reaction_10781488", "reactome": "R-SCE-5694423", "name": "NSF and SNAPs bind cis-SNARE complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781484", "species_10769994", "species_10781444" ], "products": [ "species_10781486" ], "modifiers": [], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P22804", "YIL004C", "P22213", "YDR189W", "P36015", "YKL196C", "P32854", "YOR036W", "P22214", "YLR268W", "YBL050W", "P18759", "YBR080C", "P25385", "YLR078C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P22804", "YIL004C", "P22213", "YDR189W", "P36015", "YKL196C", "P32854", "YOR036W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W" ] }, "reaction_10765501": { "compartment": "compartment_12045", "id": "reaction_10765501", "reactome": "R-SCE-162798", "name": "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_8855659" ], "products": [ "species_8855663", "species_1500596" ], "modifiers": [ [ "species_10765498", "catalyst" ] ], "additional_components": [ "YKL165C" ] }, "reaction_10781414": { "compartment": "compartment_12045", "id": "reaction_10781414", "reactome": "R-SCE-5694413", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767882", "species_10767884", "species_10767888" ], "products": [ "species_10767890" ], "modifiers": [], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "YHR098C", "YPR181C", "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P15303", "YPR181C" ] }, "reaction_10787077": { "compartment": "compartment_70101", "id": "reaction_10787077", "reactome": "R-SCE-8932276", "name": "VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10777462" ], "products": [ "species_10787065", "species_71285" ], "modifiers": [ [ "species_10787074", "catalyst" ] ], "additional_components": [ "YDL126C", "YDL126C", "Q12367", "YLR137W", "P53970", "YNL024C" ] }, "reaction_10763037": { "compartment": "compartment_70101", "id": "reaction_10763037", "reactome": "R-SCE-72672", "name": "The 60S subunit joins the translation initiation complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762687", "species_10763027", "species_10763018" ], "products": [ "species_10763029" ], "modifiers": [], "additional_components": [ "P0CX52", "RPS16B", "P35997", "RPS27A", "Q08745", "RPS10A", "P46784", "RPS10B", "P25443", "RPS2", "P06367", "RPS14A", "P0CX55", "RPS18A", "P0CX32", "RPS24B", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX35", "RPS4A", "P23248", "RPS1B", "P0CH08", "RPL40A", "P0CX47", "RPS11A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "P0CX37", "RPS6A", "P0CX56", "RPS18B", "P38711", "RPS27B", "P26786", "RPS7A", "P0CX30", "RPS23B", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P07281", "RPS19B", "P05759", "RPS31", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "species_29438", "P39730", "YAL035W", "P05748", "RPL15A", "P10622", "YDL130W", "P0CX83", "RPL19B", "P26321", "RPL5", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX23", "RPL20A", "P0CX54", "RPL12B", "P51401", "RPL9B", "P14126", "RPL3", "P0CX46", "RPL2B", "P0CH08", "RPL40A", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0CX42", "RPL23B", "P53221", "RPL26B", "P10664", "RPL4A", "P05740", "RPL17A", "P0CX27", "RPL42A", "P0CX44", "RPL1B", "P0CX28", "RPL42B", "P54780", "RPL15B", "P05744", "RPL33A", "P05759", "RPS31", "P02406", "RPL28", "P0CH09", "RPL40B", "P0C0W9", "RPL11A", "P04449", "RPL24A", "P0CX50", "RPL18B", "P41805", "RPL10", "P38061", "RPL32", "P0CX49", "RPL18A", "P0CX45", "RPL2A", "P14120", "RPL30", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P0CX43", "RPL1A", "P49166", "RPL37A", "P0CX53", "RPL12A", "P05749", "RPL22A", "P0CX82", "RPL19A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q3E757", "RPL11B", "P02400", "RPP2B", "P49626", "RPL4B", "P51402", "RPL37B", "P05743", "RPL26A", "P0C2H9", "RPL31B", "P05739", "RPL6B", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "P39730", "YAL035W", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B" ] }, "reaction_10784389": { "compartment": "compartment_6791047", "id": "reaction_10784389", "reactome": "R-SCE-6807866", "name": "GBF1 recruits ARF:GDP to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784373", "species_10784385" ], "products": [ "species_10784387" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P25386", "YDL058W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "species_29438", "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "species_29420", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438" ] }, "reaction_10770434": { "compartment": "compartment_70101", "id": "reaction_10770434", "reactome": "R-SCE-446204", "name": "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532204", "species_29494" ], "products": [ "species_111294", "species_162756" ], "modifiers": [ [ "species_10770431", "catalyst" ] ], "additional_components": [ "P43123", "YDL103C" ] }, "reaction_10776442": { "compartment": "compartment_7660", "id": "reaction_10776442", "reactome": "R-SCE-4086083", "name": "SUMOylation of ING2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776424" ], "products": [ "species_10776440", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "Q08465", "YOR064C", "P50947", "YNL097C", "P38806", "YHR090C", "Q08465", "YOR064C", "Q12306", "YDR510W", "P50947", "YNL097C", "P38806", "YHR090C", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10787541": { "compartment": "compartment_70101", "id": "reaction_10787541", "reactome": "R-SCE-8951648", "name": "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781027", "species_113592", "species_10787528" ], "products": [ "species_111294", "species_76577", "species_10787538" ], "modifiers": [ [ "species_10787528", "catalyst" ] ], "additional_components": [ "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W" ] }, "reaction_10776669": { "compartment": "compartment_7660", "id": "reaction_10776669", "reactome": "R-SCE-4615889", "name": "SUMOylation of HDAC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772638", "species_10774813" ], "products": [ "species_10776667", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "YPR068C", "P50623", "YDL064W", "Q12306", "YDR510W", "Q12306", "YDR510W", "Q12214", "YPR068C", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10770467": { "compartment": "compartment_12045", "id": "reaction_10770467", "reactome": "R-SCE-446218", "name": "Addition of the first mannose to the N-glycan precursor by ALG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449293" ], "products": [ "species_449283", "species_29420" ], "modifiers": [ [ "species_10770464", "catalyst" ] ], "additional_components": [ "YBR110W" ] }, "reaction_10770441": { "compartment": "compartment_12045", "id": "reaction_10770441", "reactome": "R-SCE-446208", "name": "Addition of a second mannose to the N-glycan precursor by ALG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449283" ], "products": [ "species_449737", "species_29420" ], "modifiers": [ [ "species_10770438", "catalyst" ] ], "additional_components": [] }, "reaction_10784396": { "compartment": "compartment_6791047", "id": "reaction_10784396", "reactome": "R-SCE-6807868", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784387", "species_113592" ], "products": [ "species_29370", "species_10784393" ], "modifiers": [ [ "species_10784387", "catalyst" ] ], "additional_components": [ "species_29420", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "species_29420", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438" ] }, "reaction_10776681": { "compartment": "compartment_7660", "id": "reaction_10776681", "reactome": "R-SCE-4615910", "name": "SUMOylation of PCNA with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10760932" ], "products": [ "species_10774805", "species_10776679" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YBR088C", "YDL064W", "Q12306", "YDR510W", "P15873", "YBR088C", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10785219": { "compartment": "compartment_70101", "id": "reaction_10785219", "reactome": "R-SCE-6814119", "name": "TRiC/CCT binds unfolded G-protein beta subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785211", "species_10769132" ], "products": [ "species_10785217" ], "modifiers": [], "additional_components": [ "YOR212W", "P39079", "YDR188W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W" ] }, "reaction_10767954": { "compartment": "compartment_70101", "id": "reaction_10767954", "reactome": "R-SCE-203977", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10767946" ], "products": [ "species_10767870", "species_29420" ], "modifiers": [ [ "species_10767951", "catalyst" ] ], "additional_components": [ "species_29420", "P20606", "YPL218W", "P20606", "YPL218W", "species_29438", "YNR026C" ] }, "reaction_10781575": { "compartment": "compartment_70101", "id": "reaction_10781575", "reactome": "R-SCE-5694527", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767892" ], "products": [ "species_10767890", "species_10767946", "species_29372", "species_10767966" ], "modifiers": [ [ "species_10767892", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "species_29438", "P15303", "YPR181C", "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P15303", "YPR181C", "species_29420", "P20606", "YPL218W", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "species_29438", "P15303", "YPR181C" ] }, "reaction_10765418": { "compartment": "compartment_70101", "id": "reaction_10765418", "reactome": "R-SCE-156910", "name": "Formation of eEF1B complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765409", "species_10765407", "species_10765414" ], "products": [ "species_10765416" ], "modifiers": [], "additional_components": [ "YAL003W", "YAL003W", "YPL048W", "P32471", "YAL003W", "P29547", "YPL048W" ] }, "reaction_10781018": { "compartment": "compartment_70101", "id": "reaction_10781018", "reactome": "R-SCE-5690319", "name": "UCHL1, UCHL3 cleave ubiquitin adducts", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781013", "species_29356" ], "products": [ "species_1131871", "species_10781015" ], "modifiers": [ [ "species_10781013", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35127", "YJR099W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35127", "YJR099W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35127", "YJR099W" ] }, "reaction_10776553": { "compartment": "compartment_13231", "id": "reaction_10776553", "reactome": "R-SCE-4551649", "name": "RANBP2 SUMOylates RANBP2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776540" ], "products": [ "species_10774805", "species_10776550" ], "modifiers": [ [ "species_10763942", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDR002W", "YDL064W", "Q12306", "YDR510W", "P41920", "YDR002W", "P40066", "YER107C", "Q02455", "YKR095W", "P36161", "YKR082W", "P52891", "YDL116W", "P38181", "YBL079W", "P53011", "YGL100W", "P20676", "YOR098C", "P47054", "YJL039C", "Q02630", "YMR047C", "P40368", "YJL061W", "Q04491", "YLR208W", "Q05166", "YDL088C", "P46673", "YJR042W", "P48837", "YGR119C", "P34077", "YFR002W", "P14907", "YJL041W", "P52593", "YML103C", "P35729", "YKL057C", "P32500", "YML031W", "P41920", "YDR002W" ] }, "reaction_10763048": { "compartment": "compartment_70101", "id": "reaction_10763048", "reactome": "R-SCE-72722", "name": "eIF2 activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10762730" ], "products": [ "species_10762728", "species_10762640", "species_29420" ], "modifiers": [ [ "species_10762728", "catalyst" ] ], "additional_components": [ "P09032", "YOR260W", "species_29420", "P32481", "GCD11", "P09064", "SUI3", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P20459", "phospho-SUI2", "P32501", "YDR211W", "P09032", "YOR260W", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P32501", "YDR211W", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438", "P09032", "YOR260W", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P32501", "YDR211W" ] }, "reaction_10765425": { "compartment": "compartment_70101", "id": "reaction_10765425", "reactome": "R-SCE-156913", "name": "Regeneration of eEF1A:GTP by eEF1B activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10765416", "species_10765420" ], "products": [ "species_10765402", "species_10765422" ], "modifiers": [ [ "species_10765416", "catalyst" ] ], "additional_components": [ "P32471", "YAL003W", "P29547", "YPL048W", "species_29420", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "species_29438", "species_29420", "P32471", "YAL003W", "P29547", "YPL048W", "P32471", "YAL003W", "P29547", "YPL048W" ] }, "reaction_10781034": { "compartment": "compartment_70101", "id": "reaction_10781034", "reactome": "R-SCE-5690808", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781025", "species_29356" ], "products": [ "species_10781031", "species_10781029" ], "modifiers": [ [ "species_10781025", "catalyst" ] ], "additional_components": [ "P35127", "YJR099W", "Q03919", "YDR139C", "YDR139C", "P35127", "YJR099W", "Q03919", "YDR139C", "P35127", "YJR099W", "Q03919", "YDR139C" ] }, "reaction_10785911": { "compartment": "compartment_70101", "id": "reaction_10785911", "reactome": "R-SCE-8853514", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785909" ], "products": [ "species_10762930", "species_10760568" ], "modifiers": [ [ "species_10785902", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P50101", "YMR304W", "P35127", "YJR099W" ] }, "reaction_10785922": { "compartment": "compartment_70101", "id": "reaction_10785922", "reactome": "R-SCE-8853515", "name": "OTULIN,USP5 cleaves UBC yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785919" ], "products": [ "species_10760592", "species_10760600", "species_10760624", "species_10760616", "species_10760584", "species_10760576", "species_10760632", "species_10760608", "species_10760568" ], "modifiers": [ [ "species_10780500", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YBR058C" ] }, "reaction_10770390": { "compartment": "compartment_12045", "id": "reaction_10770390", "reactome": "R-SCE-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449221", "species_110614" ], "products": [ "species_449299", "species_110094" ], "modifiers": [ [ "species_10770387", "catalyst" ] ], "additional_components": [ "YMR013C" ] }, "reaction_10787545": { "compartment": "compartment_70101", "id": "reaction_10787545", "reactome": "R-SCE-8951656", "name": "NEDD8-UBA3:NAE1 binds a second NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781027", "species_113592", "species_10787538" ], "products": [ "species_10787543", "species_111294", "species_76577" ], "modifiers": [], "additional_components": [ "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C" ] }, "reaction_10781572": { "compartment": "compartment_12045", "id": "reaction_10781572", "reactome": "R-SCE-5694522", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767890", "species_10767870", "species_10767966" ], "products": [ "species_10767892" ], "modifiers": [], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P15303", "YPR181C", "P20606", "YPL218W", "species_29438", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "species_29438", "P15303", "YPR181C" ] }, "reaction_10763045": { "compartment": "compartment_70101", "id": "reaction_10763045", "reactome": "R-SCE-72697", "name": "Start codon recognition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762638", "species_10762624", "species_72617", "species_10762680", "species_10762685" ], "products": [ "species_10762638", "species_10762624", "species_72617", "species_10762680", "species_10762685" ], "modifiers": [ [ "species_72617", "catalyst" ] ], "additional_components": [ "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "YMR260C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "YPR041W", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "YMR260C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "YPR041W" ] }, "reaction_10762693": { "compartment": "compartment_70101", "id": "reaction_10762693", "reactome": "R-SCE-72631", "name": "Formation of the cap-binding eIF4F complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762672", "species_10762660", "species_10762655" ], "products": [ "species_10762674" ], "modifiers": [], "additional_components": [ "P39936", "YGL049C", "P39935", "YGR162W", "YOL139C", "P10081", "YKR059W", "P39936", "YGL049C", "P07260", "YOL139C", "P10081", "YKR059W", "P39935", "YGR162W" ] }, "reaction_10784717": { "compartment": "compartment_20699", "id": "reaction_10784717", "reactome": "R-SCE-6809014", "name": "cis-Golgi cis-SNARE binds NSF and SNAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10784713" ], "products": [ "species_10784715" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "P25385", "YLR078C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P25385", "YLR078C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W" ] }, "reaction_10774816": { "compartment": "compartment_7660", "id": "reaction_10774816", "reactome": "R-SCE-2993780", "name": "Transfer of SUMO1 from E1 to UBE2I (UBC9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774753", "species_10774805" ], "products": [ "species_10774813", "species_10774738" ], "modifiers": [ [ "species_10774738", "catalyst" ] ], "additional_components": [ "P52488", "YDR390C", "Q06624", "YPR180W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W", "P52488", "YDR390C", "Q06624", "YPR180W", "P52488", "YDR390C", "Q06624", "YPR180W" ] }, "reaction_10785335": { "compartment": "compartment_6791047", "id": "reaction_10785335", "reactome": "R-SCE-6814833", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785330" ], "products": [ "species_10785328", "species_10781345" ], "modifiers": [ [ "species_10785330", "catalyst" ] ], "additional_components": [ "P01123", "YFL038C", "species_29438", "P43570", "YFL027C", "YFL027C", "species_29420", "P01123", "YFL038C", "P01123", "YFL038C", "species_29438", "P43570", "YFL027C" ] }, "reaction_10770416": { "compartment": "compartment_70101", "id": "reaction_10770416", "reactome": "R-SCE-446201", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532562" ], "products": [ "species_532531" ], "modifiers": [ [ "species_10770411", "catalyst" ] ], "additional_components": [ "YFL045C" ] }, "reaction_10766770": { "compartment": "compartment_70101", "id": "reaction_10766770", "reactome": "R-SCE-191414", "name": "MVD decarboxylates MVA5PP to IPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191403" ], "products": [ "species_29370", "species_191362", "species_113528", "species_29372" ], "modifiers": [ [ "species_10766767", "catalyst" ] ], "additional_components": [ "P32377", "YNR043W" ] }, "reaction_10767972": { "compartment": "compartment_12045", "id": "reaction_10767972", "reactome": "R-SCE-204008", "name": "SEC31:SEC13 and v-SNARE recruitment", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767898", "species_10767824", "species_10767811" ], "products": [ "species_10767900" ], "modifiers": [], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "P48415", "YPL085W", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "species_29438", "P15303", "YPR181C", "P36015", "YKL196C", "P22214", "YLR268W", "Q04491", "YLR208W", "Q12204", "YOR022C", "P38968", "YDL195W", "P25385", "YLR078C", "P48415", "YPL085W", "P38810", "YHR098C", "P20606", "YPL218W", "species_29438", "P22214", "YLR268W", "P38968", "YDL195W", "Q01590", "YLR026C", "Q04491", "YLR208W", "P53953", "YNL049C", "P40482", "YIL109C", "Q12204", "YOR022C", "P36015", "YKL196C", "P15303", "YPR181C" ] }, "reaction_10768207": { "compartment": "compartment_876", "id": "reaction_10768207", "reactome": "R-SCE-265177", "name": "Exocyst complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768198", "species_10768183", "species_10768188", "species_10768193", "species_10768178", "species_10768173", "species_10768168", "species_10768203" ], "products": [ "species_10768205" ], "modifiers": [], "additional_components": [ "YIL068C", "YGL233W", "YBR102C", "YER008C", "YLR166C", "YDR166C", "YPR055W", "YJL085W", "P38261", "YBR102C", "P33332", "YER008C", "P89102", "YDR166C", "P32844", "YIL068C", "Q06245", "YLR166C", "P22224", "YGL233W", "P32855", "YPR055W", "P19658", "YJL085W" ] }, "reaction_10783818": { "compartment": "compartment_70101", "id": "reaction_10783818", "reactome": "R-SCE-6800138", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10783797" ], "products": [ "species_71285", "species_10783804" ], "modifiers": [ [ "species_10783815", "catalyst" ] ], "additional_components": [ "P05453", "SUP35", "P12385", "SUP45", "species_29438", "P05453", "SUP35", "P12385", "SUP45", "species_29438", "P53738", "TRM112", "Q03920", "YDR140W" ] }, "reaction_10776658": { "compartment": "compartment_7660", "id": "reaction_10776658", "reactome": "R-SCE-4615873", "name": "PIAS2-2 SUMOylates SUZ12 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776647", "species_10774813" ], "products": [ "species_10774805", "species_10776655" ], "modifiers": [ [ "species_10774918", "catalyst" ] ], "additional_components": [ "YFL049W", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "Q12306", "YDR510W", "P43554", "YFL049W", "Q04195", "YDR409W", "Q12216", "YOR156C" ] }, "reaction_10770424": { "compartment": "compartment_17957", "id": "reaction_10770424", "reactome": "R-SCE-446202", "name": "Addition of the first glucose to the N-glycan precursor by ALG6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449371", "species_532542" ], "products": [ "species_449311", "species_449649" ], "modifiers": [ [ "species_10770421", "catalyst" ] ], "additional_components": [ "YOR002W" ] }, "reaction_10776717": { "compartment": "compartment_7660", "id": "reaction_10776717", "reactome": "R-SCE-4641345", "name": "SUMOylation of TOP2B with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776708" ], "products": [ "species_10776715", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YNL088W", "P06786", "YNL088W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10776630": { "compartment": "compartment_7660", "id": "reaction_10776630", "reactome": "R-SCE-4570528", "name": "SUMOylation of XPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776620" ], "products": [ "species_10776628", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDR314C", "Q12306", "YDR510W", "Q06665", "YDR314C", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10785225": { "compartment": "compartment_70101", "id": "reaction_10785225", "reactome": "R-SCE-6814120", "name": "ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785223" ], "products": [ "species_10785217", "species_29372" ], "modifiers": [], "additional_components": [ "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_113592", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W" ] }, "reaction_10771324": { "compartment": "compartment_17957", "id": "reaction_10771324", "reactome": "R-SCE-901047", "name": "Binding of ERp57", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771171", "species_10771320" ], "products": [ "species_10771322" ], "modifiers": [], "additional_components": [ "P32474", "YDR518W", "P17967", "YCL043C", "P27825", "YAL058W", "CHEBI:59080", "P32474", "YDR518W", "P27825", "YAL058W", "CHEBI:59080", "P17967", "YCL043C" ] }, "reaction_10781764": { "compartment": "compartment_70101", "id": "reaction_10781764", "reactome": "R-SCE-6781953", "name": "YOD1 binds VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781760", "species_10777462" ], "products": [ "species_10781762" ], "modifiers": [], "additional_components": [ "YFL044C", "YDL126C", "P43558", "YFL044C", "P25694", "YDL126C" ] }, "reaction_10771979": { "compartment": "compartment_20699", "id": "reaction_10771979", "reactome": "R-SCE-964830", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964828" ], "products": [ "species_964740", "species_964752" ], "modifiers": [ [ "species_10771968", "catalyst" ] ], "additional_components": [ "YLR057W" ] }, "reaction_10787190": { "compartment": "compartment_984", "id": "reaction_10787190", "reactome": "R-SCE-8940388", "name": "GPLD1 hydrolyses GPI-anchors from proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787165", "species_109276" ], "products": [ "species_2197633", "species_10787182" ], "modifiers": [ [ "species_10787187", "catalyst" ] ], "additional_components": [ "P11491", "YDR481C", "Q07825", "YLL029W", "P11491", "YDR481C", "Q07825", "YLL029W", "YJL132W" ] }, "reaction_10777575": { "compartment": "compartment_70101", "id": "reaction_10777575", "reactome": "R-SCE-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777564", "species_71284" ], "products": [ "species_71285", "species_10777567" ], "modifiers": [ [ "species_10777572", "catalyst" ] ], "additional_components": [ "YLR172C" ] }, "reaction_10785227": { "compartment": "compartment_70101", "id": "reaction_10785227", "reactome": "R-SCE-6814124", "name": "ATP binds G-protein beta associated TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10785217" ], "products": [ "species_29370", "species_10785223" ], "modifiers": [], "additional_components": [ "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_113592", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W" ] }, "reaction_10776565": { "compartment": "compartment_7660", "id": "reaction_10776565", "reactome": "R-SCE-4568863", "name": "SUMOylation of RAD52 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10764167" ], "products": [ "species_10774805", "species_10776563" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YML032C", "YDL064W", "P06778", "YML032C", "Q12306", "YDR510W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10776732": { "compartment": "compartment_7660", "id": "reaction_10776732", "reactome": "R-SCE-4641362", "name": "SUMOylation of TOP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776722" ], "products": [ "species_10776730", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YOL006C", "P04786", "YOL006C", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10787048": { "compartment": "compartment_70101", "id": "reaction_10787048", "reactome": "R-SCE-8931974", "name": "N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10765400" ], "products": [ "species_10787040", "species_71285" ], "modifiers": [ [ "species_10787045", "catalyst" ] ], "additional_components": [ "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "YGR001C" ] }, "reaction_10765485": { "compartment": "compartment_17957", "id": "reaction_10765485", "reactome": "R-SCE-162683", "name": "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_8855661" ], "products": [ "species_76194", "species_8855666" ], "modifiers": [ [ "species_10765482", "catalyst" ] ], "additional_components": [ "YJL091C" ] }, "reaction_10785867": { "compartment": "compartment_70101", "id": "reaction_10785867", "reactome": "R-SCE-8852133", "name": "UBA1 conjugates ubiquitin to UBA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785770" ], "products": [ "species_10785692", "species_76577" ], "modifiers": [ [ "species_10785770", "catalyst" ] ], "additional_components": [ "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10768446": { "compartment": "compartment_70101", "id": "reaction_10768446", "reactome": "R-SCE-351948", "name": "Mitochondrial recruitment of Drp1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768442" ], "products": [ "species_10768444" ], "modifiers": [ [ "species_10768426", "catalyst" ] ], "additional_components": [ "YKR001C", "YKR001C", "YDL072C" ] }, "reaction_10768440": { "compartment": "compartment_13231", "id": "reaction_10768440", "reactome": "R-SCE-351947", "name": "Nuclear translocation of catalytic domain of Mst3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768434" ], "products": [ "species_10768438" ], "modifiers": [], "additional_components": [ "YHR102W", "YHR102W" ] }, "reaction_10768282": { "compartment": "compartment_7660", "id": "reaction_10768282", "reactome": "R-SCE-266204", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768278", "species_29428" ], "products": [ "species_10768280" ], "modifiers": [], "additional_components": [ "Q03435", "YDL002C", "Q02486", "YMR072W", "P33417", "YKL032C", "Q03973", "YDR174W", "P11633", "YBR089C-A", "Q03435", "YDL002C", "Q02486", "YMR072W", "P33417", "YKL032C", "Q03973", "YDR174W", "P11633", "YBR089C-A" ] }, "reaction_10786382": { "compartment": "compartment_70616", "id": "reaction_10786382", "reactome": "R-SCE-8867344", "name": "OMA1 hydrolyses OPA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_10786358" ], "products": [ "species_10786366", "species_10786374" ], "modifiers": [ [ "species_10786379", "catalyst" ] ], "additional_components": [ "P54861", "YLL001W", "P21576", "YKR001C", "P32266", "YOR211C", "P54861", "YLL001W", "P21576", "YKR001C", "P32266", "YOR211C", "P54861", "YLL001W", "P21576", "YKR001C", "P32266", "YOR211C", "YKR087C" ] }, "reaction_10761417": { "compartment": "compartment_5460", "id": "reaction_10761417", "reactome": "R-SCE-70501", "name": "Pyruvate + CO2 + ATP => ADP + Orthophosphate + Oxaloacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29376", "species_113557", "species_113593" ], "products": [ "species_113548", "species_113581", "species_113587" ], "modifiers": [ [ "species_10761414", "catalyst" ], [ "species_113559", "catalyst" ] ], "additional_components": [ "P11154", "YGL062W", "species_199207", "species_113527" ] }, "reaction_10761343": { "compartment": "compartment_70101", "id": "reaction_10761343", "reactome": "R-SCE-70482", "name": "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_29800" ], "products": [ "species_29578", "species_29360", "species_29372" ], "modifiers": [ [ "species_10761261", "catalyst" ] ], "additional_components": [ "P00360", "YJL052W", "P00358", "YJR009C", "P00359", "YGR192C" ] }, "reaction_10768527": { "compartment": "compartment_70101", "id": "reaction_10768527", "reactome": "R-SCE-372449", "name": "phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] => phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_372364", "species_76190" ], "products": [ "species_29654", "species_29492" ], "modifiers": [ [ "species_10764027", "catalyst" ] ], "additional_components": [ "YBR291C" ] }, "reaction_10761339": { "compartment": "compartment_70101", "id": "reaction_10761339", "reactome": "R-SCE-70479", "name": "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30014", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10761336", "catalyst" ], [ "species_76577", "inhibitor" ] ], "additional_components": [ "P09201", "YLR377C", "species_109496" ] }, "reaction_10762171": { "compartment": "compartment_5460", "id": "reaction_10762171", "reactome": "R-SCE-71783", "name": "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113587", "species_113529" ], "products": [ "species_113526", "species_113544" ], "modifiers": [ [ "species_10761676", "catalyst" ] ], "additional_components": [ "P17505", "YKL085W" ] }, "reaction_10761407": { "compartment": "compartment_70101", "id": "reaction_10761407", "reactome": "R-SCE-70494", "name": "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29492", "species_29356" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10761404", "catalyst" ] ], "additional_components": [ "P42222", "YMR323W", "P00924", "YGR254W", "P00925", "YHR174W", "P0CX11", "YPL281C", "P0CX10", "YOR393W", "species_109496" ] }, "reaction_10761341": { "compartment": "compartment_70101", "id": "reaction_10761341", "reactome": "R-SCE-70481", "name": "D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29578" ], "products": [ "species_75970" ], "modifiers": [ [ "species_10761271", "catalyst" ] ], "additional_components": [ "P00942", "YDR050C" ] }, "reaction_10768555": { "compartment": "compartment_70101", "id": "reaction_10768555", "reactome": "R-SCE-372843", "name": "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_113544" ], "products": [ "species_113548", "species_198498" ], "modifiers": [ [ "species_10768552", "catalyst" ] ], "additional_components": [ "YLR348C" ] }, "reaction_10761359": { "compartment": "compartment_70101", "id": "reaction_10761359", "reactome": "R-SCE-70486", "name": "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29728" ], "products": [ "species_29370", "species_29800" ], "modifiers": [ [ "species_10761356", "catalyst" ] ], "additional_components": [ "P00560", "YCR012W", "species_109496" ] }, "reaction_10788348": { "compartment": "compartment_70101", "id": "reaction_10788348", "reactome": "R-SCE-9020257", "name": "LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024893", "species_29356" ], "products": [ "species_9024879" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10788372": { "compartment": "compartment_70101", "id": "reaction_10788372", "reactome": "R-SCE-9024890", "name": "LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024873" ], "products": [ "species_9024886" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10784338": { "compartment": "compartment_70101", "id": "reaction_10784338", "reactome": "R-SCE-6807105", "name": "Monoubiquitinated PTEN translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784332" ], "products": [ "species_10784336" ], "modifiers": [], "additional_components": [ "YNL128W", "YNL128W" ] }, "reaction_10784343": { "compartment": "compartment_7660", "id": "reaction_10784343", "reactome": "R-SCE-6807118", "name": "USP7 deubiquitinates monoubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10784336" ], "products": [ "species_10784340", "species_10760537" ], "modifiers": [ [ "species_10779695", "catalyst" ] ], "additional_components": [ "YNL128W", "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YMR304W" ] }, "reaction_10784345": { "compartment": "compartment_7660", "id": "reaction_10784345", "reactome": "R-SCE-6807126", "name": "Deubiquitinated PTEN translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784340" ], "products": [ "species_10767316" ], "modifiers": [], "additional_components": [ "YNL128W", "YNL128W" ] }, "reaction_10769655": { "compartment": "compartment_876", "id": "reaction_10769655", "reactome": "R-SCE-425822", "name": "K+-independent Li+/Ca2+ exchanger transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_425815" ], "products": [ "species_425810", "species_74112" ], "modifiers": [ [ "species_10769652", "catalyst" ] ], "additional_components": [ "YJR106W" ] }, "reaction_10787919": { "compartment": "compartment_7660", "id": "reaction_10787919", "reactome": "R-SCE-9009533", "name": "TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763232", "species_10763417", "species_10787915" ], "products": [ "species_10787917" ], "modifiers": [], "additional_components": [ "P32774", "YKL058W", "P32773", "YOR194C", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P42944", "YJL110C", "P43574", "YFL021W", "P25364", "YCR065W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P18494", "YER040W", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P42944", "YJL110C", "P32774", "YKL058W", "P32773", "YOR194C", "P43574", "YFL021W", "P25364", "YCR065W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P13393", "SPT15", "P18494", "YER040W" ] }, "reaction_10787967": { "compartment": "compartment_7660", "id": "reaction_10787967", "reactome": "R-SCE-9012319", "name": "p-TEFb phosphorylates serine 2 in RNA polymerase II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10787962" ], "products": [ "species_113582", "species_10787964" ], "modifiers": [ [ "species_10787962", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "CHEBI:50114", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q05949", "YLR226W", "P34087", "YDR404C", "P22139", "RPB10", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "CHEBI:50114", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "Q05949", "YLR226W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "CHEBI:50114", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q05949", "YLR226W", "P34087", "YDR404C", "P22139", "RPB10", "P46962", "YJL006C" ] }, "reaction_10787903": { "compartment": "compartment_7660", "id": "reaction_10787903", "reactome": "R-SCE-9009065", "name": "FOXA1 and GATA3 bind to CCND1 promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787891", "species_10787885", "species_10787899" ], "products": [ "species_10772638", "species_10787901", "species_10787879" ], "modifiers": [], "additional_components": [ "P25364", "YCR065W", "P40466", "YIL131C", "P02294", "YBL002W", "P02309", "YBR009C", "Q03125", "YDR043C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "Q12214", "YPR068C", "P42944", "YJL110C", "P43574", "YFL021W", "P18494", "YER040W", "YPR068C", "P42944", "YJL110C", "P02293", "YDR224C", "P25364", "YCR065W", "P04912", "YBL003C", "P04911", "YDR225W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "Q12692", "YOL012C", "P43574", "YFL021W", "P40466", "YIL131C", "P61830", "YBR010W", "P18494", "YER040W", "YDR043C" ] }, "reaction_10787934": { "compartment": "compartment_7660", "id": "reaction_10787934", "reactome": "R-SCE-9011949", "name": "KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787929" ], "products": [ "species_10787931", "species_10776763" ], "modifiers": [ [ "species_10787929", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P39956", "YER169W", "CHEBI:50114", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "CHEBI:50114", "YER169W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P39956", "YER169W", "CHEBI:50114" ] }, "reaction_10788368": { "compartment": "compartment_7660", "id": "reaction_10788368", "reactome": "R-SCE-9023860", "name": "Histone acetyltransferases are recruited to the TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788364", "species_10788356" ], "products": [ "species_10788366" ], "modifiers": [], "additional_components": [ "P38074", "YBR034C", "P42944", "YJL110C", "P32774", "YKL058W", "P25364", "YCR065W", "P13393", "SPT15", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P32773", "YOR194C", "P43574", "YFL021W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P18494", "YER040W", "P34218", "YBL052C", "Q03330", "YGR252W", "P38074", "YBR034C", "P42944", "YJL110C", "P32774", "YKL058W", "P25364", "YCR065W", "P13393", "SPT15", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P34218", "YBL052C", "Q03330", "YGR252W", "P32773", "YOR194C", "P43574", "YFL021W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P18494", "YER040W" ] }, "reaction_10788370": { "compartment": "compartment_7660", "id": "reaction_10788370", "reactome": "R-SCE-9023861", "name": "PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787917", "species_10775032" ], "products": [ "species_10788362" ], "modifiers": [], "additional_components": [ "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P42944", "YJL110C", "P32774", "YKL058W", "P32773", "YOR194C", "P43574", "YFL021W", "P25364", "YCR065W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P13393", "SPT15", "P18494", "YER040W", "YBR034C", "P38074", "YBR034C", "P42944", "YJL110C", "P32774", "YKL058W", "P25364", "YCR065W", "P13393", "SPT15", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P32773", "YOR194C", "P43574", "YFL021W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P18494", "YER040W" ] }, "reaction_10766225": { "compartment": "compartment_13231", "id": "reaction_10766225", "reactome": "R-SCE-170825", "name": "glucokinase [nucleoplasm] => glucokinase [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766223" ], "products": [ "species_10761199" ], "modifiers": [], "additional_components": [ "Q04409", "YDR516C", "Q06204", "YLR446W", "P04806", "YFR053C", "P17709", "YCL040W", "P04807", "YGL253W", "Q04409", "YDR516C", "Q06204", "YLR446W", "P04806", "YFR053C", "P17709", "YCL040W", "P04807", "YGL253W" ] }, "reaction_10767350": { "compartment": "compartment_7660", "id": "reaction_10767350", "reactome": "R-SCE-199839", "name": "AKT can phosphorylate RSK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10767323" ], "products": [ "species_113582", "species_10767327" ], "modifiers": [ [ "species_10767347", "catalyst" ] ], "additional_components": [ "YBR028C", "YBR028C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10767701": { "compartment": "compartment_876", "id": "reaction_10767701", "reactome": "R-SCE-202692", "name": "PIP3 binds to RhoA and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765227", "species_179838" ], "products": [ "species_10767699" ], "modifiers": [], "additional_components": [ "YPR165W", "P06780", "YPR165W", "species_179838" ] }, "reaction_10788521": { "compartment": "compartment_70101", "id": "reaction_10788521", "reactome": "R-SCE-9603279", "name": "PIP3 recruits PDK1 and AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767662", "species_179838", "species_10769080" ], "products": [ "species_10788519" ], "modifiers": [], "additional_components": [ "YOL100W", "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "Q12236", "YOL100W", "P11792", "YHR205W" ] }, "reaction_10788567": { "compartment": "compartment_17947", "id": "reaction_10788567", "reactome": "R-SCE-9603775", "name": "PEX3:PEX19:class I PMP dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788555" ], "products": [ "species_10768844", "species_10788565", "species_10768864" ], "modifiers": [], "additional_components": [ "P53112", "PEX14", "P28737", "YGR028W", "P28795", "YDR329C", "Q07418", "YDL065C", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C", "YDR329C", "P53112", "PEX14", "P28737", "YGR028W", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C", "YDL065C" ] }, "reaction_10788569": { "compartment": "compartment_17947", "id": "reaction_10788569", "reactome": "R-SCE-9603784", "name": "PEX19:class I PMP binds PEX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788553", "species_10768844" ], "products": [ "species_10788555" ], "modifiers": [], "additional_components": [ "P53112", "PEX14", "P28737", "YGR028W", "Q07418", "YDL065C", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C", "YDR329C", "P53112", "PEX14", "P28737", "YGR028W", "P28795", "YDR329C", "Q07418", "YDL065C", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C" ] }, "reaction_10788571": { "compartment": "compartment_70101", "id": "reaction_10788571", "reactome": "R-SCE-9603804", "name": "PEX19 binds class I peroxisomal membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788551", "species_10768864" ], "products": [ "species_10788553" ], "modifiers": [], "additional_components": [ "P53112", "PEX14", "P28737", "YGR028W", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C", "YDL065C", "P53112", "PEX14", "P28737", "YGR028W", "Q07418", "YDL065C", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C" ] }, "reaction_10765200": { "compartment": "compartment_7660", "id": "reaction_10765200", "reactome": "R-SCE-113430", "name": "Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764338" ], "products": [ "species_10764338" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10764341": { "compartment": "compartment_7660", "id": "reaction_10764341", "reactome": "R-SCE-77071", "name": "Phosphorylation (Ser5) of RNA pol II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10764338" ], "products": [ "species_113582", "species_10764334" ], "modifiers": [ [ "species_10764338", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10764281": { "compartment": "compartment_7660", "id": "reaction_10764281", "reactome": "R-SCE-76056", "name": "Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764229", "species_10764277" ], "products": [ "species_10764279" ], "modifiers": [], "additional_components": [ "Q06339", "YDR362C", "P46678", "BDP1", "P29056", "BRF1", "P32367", "TFC1", "P33339", "TFC4", "P32805", "YGL254W", "P34111", "TFC3", "P13393", "SPT15", "P20434", "RPB5", "P32910", "RPC34", "P35718", "RPC25", "P20435", "RPO26", "P25441", "RPC53", "P07703", "RPC40", "P17890", "RPC31", "P22276", "RET1", "P20436", "RPB8", "P32349", "RPC82", "P47076", "RPC17", "P40422", "RPC10", "Q04307", "RPC11", "P22139", "RPB10", "P04051", "RPO31", "P20434", "RPB5", "Q06339", "YDR362C", "P46678", "BDP1", "P29056", "BRF1", "P32910", "RPC34", "P35718", "RPC25", "P32367", "TFC1", "P20435", "RPO26", "P25441", "RPC53", "P07703", "RPC40", "P17890", "RPC31", "P22276", "RET1", "P13393", "SPT15", "P20436", "RPB8", "P32349", "RPC82", "P47076", "RPC17", "P33339", "TFC4", "P40422", "RPC10", "Q04307", "RPC11", "P32805", "YGL254W", "P22139", "RPB10", "P04051", "RPO31", "P34111", "TFC3" ] }, "reaction_10764473": { "compartment": "compartment_7660", "id": "reaction_10764473", "reactome": "R-SCE-83805", "name": "Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764469", "species_10764277" ], "products": [ "species_10764471" ], "modifiers": [], "additional_components": [ "Q06339", "YDR362C", "P46678", "BDP1", "P29056", "BRF1", "P32367", "TFC1", "P33339", "TFC4", "P34111", "TFC3", "P13393", "SPT15", "P20434", "RPB5", "P32910", "RPC34", "P35718", "RPC25", "P20435", "RPO26", "P25441", "RPC53", "P07703", "RPC40", "P17890", "RPC31", "P22276", "RET1", "P20436", "RPB8", "P32349", "RPC82", "P47076", "RPC17", "P40422", "RPC10", "Q04307", "RPC11", "P22139", "RPB10", "P04051", "RPO31", "P20434", "RPB5", "Q06339", "YDR362C", "P46678", "BDP1", "P29056", "BRF1", "P32910", "RPC34", "P35718", "RPC25", "P32367", "TFC1", "P20435", "RPO26", "P25441", "RPC53", "P07703", "RPC40", "P17890", "RPC31", "P22276", "RET1", "P13393", "SPT15", "P20436", "RPB8", "P32349", "RPC82", "P47076", "RPC17", "P33339", "TFC4", "P40422", "RPC10", "Q04307", "RPC11", "P22139", "RPB10", "P04051", "RPO31", "P34111", "TFC3" ] }, "reaction_10764192": { "compartment": "compartment_7660", "id": "reaction_10764192", "reactome": "R-SCE-76052", "name": "Binding of TFIIIA To type 1 Promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76050", "species_10764188" ], "products": [ "species_10764190" ], "modifiers": [], "additional_components": [ "YGL254W", "P32805", "YGL254W" ] }, "reaction_10765180": { "compartment": "compartment_7660", "id": "reaction_10765180", "reactome": "R-SCE-112396", "name": "Separation of elongating transcript from template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765176" ], "products": [ "species_10765178" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765194": { "compartment": "compartment_7660", "id": "reaction_10765194", "reactome": "R-SCE-113412", "name": "Pol II elongation complex moves on the template as transcript elongates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10765164" ], "products": [ "species_9757634", "species_10765176" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765188": { "compartment": "compartment_7660", "id": "reaction_10765188", "reactome": "R-SCE-113407", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764987", "species_10764978" ], "products": [ "species_10764989" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10", "P27692", "YML010W", "P32914", "YGR063C", "P41896", "YGR005C", "P20434", "RPB5", "P27692", "YML010W", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P32914", "YGR063C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10765166": { "compartment": "compartment_7660", "id": "reaction_10765166", "reactome": "R-SCE-112385", "name": "Addition of nucleotides leads to transcript elongation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10765162" ], "products": [ "species_10763293", "species_10765164" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53861", "YNL230C", "P53930", "YNL107W", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P06839", "RAD3", "P46962", "YJL006C", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765033": { "compartment": "compartment_7660", "id": "reaction_10765033", "reactome": "R-SCE-112383", "name": "Hypophosphorylation of RNA Pol II CTD by FCP1P protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762306", "species_10763293", "species_10764985" ], "products": [ "species_10764987", "species_10763293" ], "modifiers": [ [ "species_10764985", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "YMR277W", "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "YMR277W" ] }, "reaction_10788729": { "compartment": "compartment_876", "id": "reaction_10788729", "reactome": "R-SCE-9632858", "name": "PRKCZ autophosphorylates downstream of estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10788721" ], "products": [ "species_29370", "species_10788726" ], "modifiers": [ [ "species_10788721", "catalyst" ] ], "additional_components": [ "P24583", "YBL105C", "species_179838", "Q12236", "YOL100W", "P24583", "YBL105C", "species_179838", "Q12236", "YOL100W", "P24583", "YBL105C", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10788731": { "compartment": "compartment_7660", "id": "reaction_10788731", "reactome": "R-SCE-9632910", "name": "ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775860" ], "products": [ "species_10767242" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "P16892", "YBL016W" ] }, "reaction_10788690": { "compartment": "compartment_876", "id": "reaction_10788690", "reactome": "R-SCE-9625814", "name": "SPHK1 phosphorylates sphingosine in response to E2 stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1606609" ], "products": [ "species_5218688" ], "modifiers": [ [ "species_10769088", "catalyst" ] ], "additional_components": [ "YLR260W" ] }, "reaction_10786822": { "compartment": "compartment_70101", "id": "reaction_10786822", "reactome": "R-SCE-8875623", "name": "SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29404" ], "products": [ "species_113552", "species_113529" ], "modifiers": [ [ "species_10786819", "catalyst" ] ], "additional_components": [ "Q99297", "YOR222W", "Q03028", "YPL134C" ] }, "reaction_10775307": { "compartment": "compartment_20699", "id": "reaction_10775307", "reactome": "R-SCE-3247836", "name": "Retromer recycles WLS to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775301" ], "products": [ "species_10775305" ], "modifiers": [], "additional_components": [ "Q08826", "YOR357C", "P38759", "YHR012W", "P40335", "YJL053W", "P34110", "YJL154C", "Q08826", "YOR357C", "P38759", "YHR012W", "P40335", "YJL053W", "P34110", "YJL154C" ] }, "reaction_10768807": { "compartment": "compartment_70101", "id": "reaction_10768807", "reactome": "R-SCE-381727", "name": "RAP1A exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768805", "species_29438" ], "products": [ "species_10768481", "species_29420" ], "modifiers": [], "additional_components": [ "species_111349", "P13856", "YGR152C", "species_29438", "P13856", "YGR152C" ] }, "reaction_10781313": { "compartment": "compartment_5460", "id": "reaction_10781313", "reactome": "R-SCE-5694018", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781300", "species_113526" ], "products": [ "species_10781283", "species_29362", "species_113529" ], "modifiers": [ [ "species_10781310", "catalyst" ] ], "additional_components": [ "CHEBI:50746", "P39726", "YAL044C", "YAL044C", "P09624", "YFL018C", "species_113596" ] }, "reaction_10781298": { "compartment": "compartment_5460", "id": "reaction_10781298", "reactome": "R-SCE-5693967", "name": "PXLP-K754-GLDC dimer decarboxylates Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781283", "species_159549" ], "products": [ "species_29376", "species_10781287" ], "modifiers": [ [ "species_10781295", "catalyst" ] ], "additional_components": [ "YAL044C", "CHEBI:14949", "P39726", "YAL044C", "P49095", "YMR189W" ] }, "reaction_10781308": { "compartment": "compartment_5460", "id": "reaction_10781308", "reactome": "R-SCE-5693977", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_10781287" ], "products": [ "species_5693984", "species_10781300", "species_5693978" ], "modifiers": [ [ "species_10781305", "catalyst" ] ], "additional_components": [ "CHEBI:14949", "P39726", "YAL044C", "CHEBI:50746", "P39726", "YAL044C", "YDR019C" ] }, "reaction_10769352": { "compartment": "compartment_876", "id": "reaction_10769352", "reactome": "R-SCE-418582", "name": "G alpha (q) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764870" ], "products": [ "species_10769349" ], "modifiers": [ [ "species_10764870", "catalyst" ] ], "additional_components": [ "species_29438", "P10823", "YER020W", "species_111349", "P10823", "YER020W", "species_29438", "P10823", "YER020W" ] }, "reaction_10765298": { "compartment": "compartment_876", "id": "reaction_10765298", "reactome": "R-SCE-114688", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765293" ], "products": [ "species_10765295" ], "modifiers": [ [ "species_10764872", "catalyst" ] ], "additional_components": [ "P32383", "YPL268W", "species_29438", "species_179856", "P10823", "YER020W", "species_114520", "P32383", "YPL268W", "species_6797635", "species_29438", "P10823", "YER020W", "P32383", "YPL268W", "species_29438", "P10823", "YER020W" ] }, "reaction_10769199": { "compartment": "compartment_876", "id": "reaction_10769199", "reactome": "R-SCE-400015", "name": "Diacylgycerol activates Protein kinase C, alpha type", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765240", "species_114519" ], "products": [ "species_10769197" ], "modifiers": [], "additional_components": [ "YBL105C", "P24583", "YBL105C", "species_6797635" ] }, "reaction_10787442": { "compartment": "compartment_70101", "id": "reaction_10787442", "reactome": "R-SCE-8948039", "name": "FUNDC1 is phosphorylated by CK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787437", "species_113592" ], "products": [ "species_29370", "species_10787440" ], "modifiers": [ [ "species_10774577", "catalyst" ] ], "additional_components": [ "YAL008W", "YAL008W", "P15790", "CKA1", "P38930", "CKB2", "P19454", "CKA2" ] }, "reaction_10787455": { "compartment": "compartment_17906", "id": "reaction_10787455", "reactome": "R-SCE-8948146", "name": "FUNDC1 is phosphorylated by ULK1 at Ser17", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787437", "species_113592" ], "products": [ "species_29370", "species_10787452" ], "modifiers": [ [ "species_10787444", "catalyst" ] ], "additional_components": [ "YAL008W", "YAL008W", "YGL180W" ] }, "reaction_10787722": { "compartment": "compartment_21994", "id": "reaction_10787722", "reactome": "R-SCE-8959571", "name": "LC3 binds the autophagosome membrane Atg5-Atg12 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787718", "species_10777022" ], "products": [ "species_10787720" ], "modifiers": [], "additional_components": [ "P18411", "YAL008W", "P38182", "YBL078C", "Q12380", "YPL149W", "P38316", "YBR217W", "Q12380", "YPL149W", "P18411", "YAL008W", "P38316", "YBR217W", "P38182", "YBL078C" ] }, "reaction_10787446": { "compartment": "compartment_17906", "id": "reaction_10787446", "reactome": "R-SCE-8948136", "name": "ULK1 Translocates to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778616" ], "products": [ "species_10787444" ], "modifiers": [], "additional_components": [ "YGL180W", "YGL180W" ] }, "reaction_10787724": { "compartment": "compartment_70101", "id": "reaction_10787724", "reactome": "R-SCE-8959573", "name": "Phosphorylated FUNDC1 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779041", "species_10787452" ], "products": [ "species_10787718" ], "modifiers": [], "additional_components": [ "YBL078C", "YAL008W", "P18411", "YAL008W", "P38182", "YBL078C" ] }, "reaction_10788643": { "compartment": "compartment_70101", "id": "reaction_10788643", "reactome": "R-SCE-9617595", "name": "SGTA binds mislocalized membrane protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788608", "species_10788577" ], "products": [ "species_10788641" ], "modifiers": [], "additional_components": [ "P33328", "YOR327C", "P31109", "YAL030W", "Q12118", "SGT2", "P33328", "YOR327C", "Q12118", "SGT2", "P31109", "YAL030W" ] }, "reaction_10788616": { "compartment": "compartment_70101", "id": "reaction_10788616", "reactome": "R-SCE-9609921", "name": "SGTA binds Tail-anchored protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788612", "species_10788577" ], "products": [ "species_10788614" ], "modifiers": [], "additional_components": [ "Q01590", "YLR026C", "P33296", "YER100W", "P35179", "YDR086C", "P52871", "YER019C-A", "P32867", "YPL232W", "P33328", "YOR327C", "Q04458", "YMR110C", "P40075", "YER120W", "P38374", "YBR162W-A", "P31109", "YAL030W", "P40312", "YNL111C", "P39926", "YMR183C", "Q12118", "SGT2", "Q01590", "YLR026C", "P33296", "YER100W", "P35179", "YDR086C", "P52871", "YER019C-A", "P32867", "YPL232W", "P33328", "YOR327C", "Q04458", "YMR110C", "P40075", "YER120W", "P38374", "YBR162W-A", "Q12118", "SGT2", "P31109", "YAL030W", "P40312", "YNL111C", "P39926", "YMR183C" ] }, "reaction_10773413": { "compartment": "compartment_876", "id": "reaction_10773413", "reactome": "R-SCE-1640164", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429776", "species_29356" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10773410", "catalyst" ] ], "additional_components": [ "P39997", "YEL016C", "P25353", "YCR026C" ] }, "reaction_10773363": { "compartment": "compartment_876", "id": "reaction_10773363", "reactome": "R-SCE-1606273", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429776", "species_29356" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10773360", "catalyst" ] ], "additional_components": [ "P40015", "YER019W", "species_109496" ] }, "reaction_10785153": { "compartment": "compartment_7660", "id": "reaction_10785153", "reactome": "R-SCE-6811522", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_6810408" ], "products": [ "species_113582", "species_6810412" ], "modifiers": [ [ "species_10785150", "catalyst" ] ], "additional_components": [ "P38994", "YDR208W" ] }, "reaction_10768746": { "compartment": "compartment_5460", "id": "reaction_10768746", "reactome": "R-SCE-380608", "name": "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380598", "species_113526" ], "products": [ "species_380593", "species_29362", "species_113529" ], "modifiers": [ [ "species_10762134", "catalyst" ] ], "additional_components": [ "P40047", "YER073W" ] }, "reaction_10766908": { "compartment": "compartment_70101", "id": "reaction_10766908", "reactome": "R-SCE-194678", "name": "CYP51A1 demethylates LNSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194634", "species_29368" ], "products": [ "species_29366", "species_194644", "species_29460", "species_29356" ], "modifiers": [ [ "species_10766905", "catalyst" ] ], "additional_components": [ "YHR007C" ] }, "reaction_10776925": { "compartment": "compartment_7660", "id": "reaction_10776925", "reactome": "R-SCE-5082384", "name": "HSP70:DNAJB1 binds HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775782", "species_10775812" ], "products": [ "species_10775814" ], "modifiers": [], "additional_components": [ "P36016", "YKL073W", "P25294", "YNL007C", "P22202", "YER103W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P38889", "YHR206W", "P10961", "YGL073W", "P36016", "YKL073W", "P25294", "YNL007C", "P22202", "YER103W", "P38889", "YHR206W", "P09435", "YBL075C", "P10592", "YLL024C", "P10961", "YGL073W", "P10591", "YAL005C" ] }, "reaction_10788335": { "compartment": "compartment_70101", "id": "reaction_10788335", "reactome": "R-SCE-9018824", "name": "RHOT2 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788331", "species_10788314" ], "products": [ "species_10788333" ], "modifiers": [], "additional_components": [ "P32492", "YAL029C", "P38297", "YBR179C", "P19524", "YOR326W", "species_29438", "P39722", "YAL048C", "P32492", "YAL029C", "P38297", "YBR179C", "species_29438", "P19524", "YOR326W", "P39722", "YAL048C" ] }, "reaction_10788319": { "compartment": "compartment_70101", "id": "reaction_10788319", "reactome": "R-SCE-9018814", "name": "RHOT1 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788314", "species_29356" ], "products": [ "species_10788316", "species_29372" ], "modifiers": [ [ "species_10788314", "catalyst" ] ], "additional_components": [ "species_29438", "P39722", "YAL048C", "species_29420", "P39722", "YAL048C", "species_29438", "P39722", "YAL048C" ] }, "reaction_10788329": { "compartment": "compartment_17906", "id": "reaction_10788329", "reactome": "R-SCE-9018815", "name": "RHOT1 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788325", "species_10788314" ], "products": [ "species_10788327" ], "modifiers": [], "additional_components": [ "P32492", "YAL029C", "P19524", "YOR326W", "species_29438", "P39722", "YAL048C", "P32492", "YAL029C", "species_29438", "P19524", "YOR326W", "P39722", "YAL048C" ] }, "reaction_10788337": { "compartment": "compartment_70101", "id": "reaction_10788337", "reactome": "R-SCE-9018826", "name": "RHOT2 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788314", "species_29356" ], "products": [ "species_10788316", "species_29372" ], "modifiers": [ [ "species_10788314", "catalyst" ] ], "additional_components": [ "species_29438", "P39722", "YAL048C", "species_29420", "P39722", "YAL048C", "species_29438", "P39722", "YAL048C" ] }, "reaction_10769669": { "compartment": "compartment_172574", "id": "reaction_10769669", "reactome": "R-SCE-425965", "name": "SLC9A9 exchanges Na+ for H+ across the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_83910", "species_425999" ], "products": [ "species_70106", "species_425977" ], "modifiers": [ [ "species_10769666", "catalyst" ] ], "additional_components": [ "YDR456W" ] }, "reaction_10769676": { "compartment": "compartment_171062", "id": "reaction_10769676", "reactome": "R-SCE-425983", "name": "SLC9A6,7 exchange Na+ for H+ across the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425978", "species_83910" ], "products": [ "species_70106", "species_425971" ], "modifiers": [ [ "species_10769671", "catalyst" ] ], "additional_components": [ "YDR456W" ] }, "reaction_10769681": { "compartment": "compartment_20699", "id": "reaction_10769681", "reactome": "R-SCE-426015", "name": "Na+/H+ exchanger transport (at trans-golgi membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425969", "species_83910" ], "products": [ "species_70106", "species_425958" ], "modifiers": [ [ "species_10769678", "catalyst" ] ], "additional_components": [ "YDR456W" ] }, "reaction_10766728": { "compartment": "compartment_70101", "id": "reaction_10766728", "reactome": "R-SCE-191366", "name": "Squalene 2,3-epoxide cyclizes, forming lanosterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191309" ], "products": [ "species_194634" ], "modifiers": [ [ "species_10766725", "catalyst" ] ], "additional_components": [ "YHR072W" ] }, "reaction_10787021": { "compartment": "compartment_5460", "id": "reaction_10787021", "reactome": "R-SCE-8878815", "name": "Formation of 4Fe-4S cluster on ISCA1:ISCA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787001", "species_10787013" ], "products": [ "species_10786999", "species_10787015" ], "modifiers": [ [ "species_10787019", "catalyst" ] ], "additional_components": [ "CHEBI:33739", "Q02784", "YPL059W", "Q12425", "YPR067W", "Q07821", "YLL027W", "YPL059W", "Q12425", "YPR067W", "CHEBI:49883", "Q07821", "YLL027W" ] }, "reaction_10789204": { "compartment": "compartment_70101", "id": "reaction_10789204", "reactome": "R-SCE-9705714", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_29366", "species_469662" ], "modifiers": [ [ "species_10776525", "catalyst" ] ], "additional_components": [ "YIL049W" ] }, "reaction_10785545": { "compartment": "compartment_984", "id": "reaction_10785545", "reactome": "R-SCE-8851129", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8870906", "species_109276" ], "products": [ "species_8870962", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785539", "catalyst" ] ], "additional_components": [ "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10781870": { "compartment": "compartment_70101", "id": "reaction_10781870", "reactome": "R-SCE-6783221", "name": "HAGH hydrolyses (R)-S-LGSH to GSH and LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694130" ], "products": [ "species_29450", "species_29708" ], "modifiers": [ [ "species_10781867", "catalyst" ] ], "additional_components": [ "species_158417", "Q12320", "YOR040W" ] }, "reaction_10767283": { "compartment": "compartment_70101", "id": "reaction_10767283", "reactome": "R-SCE-198845", "name": "CYB5A:heme reduces Asc.- to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767269", "species_1497805" ], "products": [ "species_10767267", "species_198816" ], "modifiers": [ [ "species_10767269", "catalyst" ] ], "additional_components": [ "species_189444", "P40312", "YNL111C", "CHEBI:36144", "P40312", "YNL111C", "species_189444", "P40312", "YNL111C" ] }, "reaction_10771989": { "compartment": "compartment_70101", "id": "reaction_10771989", "reactome": "R-SCE-964958", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964945", "species_113592" ], "products": [ "species_29370", "species_965146" ], "modifiers": [ [ "species_10771986", "catalyst" ] ], "additional_components": [ "species_158417", "P39988", "YEL029C" ] }, "reaction_10769063": { "compartment": "compartment_17951", "id": "reaction_10769063", "reactome": "R-SCE-390291", "name": "acetyl-CoA + carnitine => acetylcarnitine + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390294", "species_353123" ], "products": [ "species_193514", "species_390287" ], "modifiers": [ [ "species_10769058", "catalyst" ] ], "additional_components": [ "YML042W" ] }, "reaction_10773576": { "compartment": "compartment_12045", "id": "reaction_10773576", "reactome": "R-SCE-1676124", "name": "PI4P is dephosphorylated to PI by SACM1L at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806234", "species_29356" ], "products": [ "species_426639", "species_29372" ], "modifiers": [ [ "species_10773573", "catalyst" ] ], "additional_components": [ "YKL212W" ] }, "reaction_10771313": { "compartment": "compartment_70101", "id": "reaction_10771313", "reactome": "R-SCE-893596", "name": "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398", "species_29970" ], "products": [ "species_893615", "species_29432" ], "modifiers": [ [ "species_10771307", "catalyst" ], [ "species_8939576", "inhibitor" ], [ "species_29502", "inhibitor" ] ], "additional_components": [ "P47039", "YJL060W", "CHEBI:55528", "CHEBI:43580" ] }, "reaction_10778606": { "compartment": "compartment_70101", "id": "reaction_10778606", "reactome": "R-SCE-5662466", "name": "XYLB phosphorylates D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5661281", "species_113592" ], "products": [ "species_29370", "species_29790" ], "modifiers": [ [ "species_10778603", "catalyst" ] ], "additional_components": [ "YGR194C" ] }, "reaction_10763390": { "compartment": "compartment_70101", "id": "reaction_10763390", "reactome": "R-SCE-73813", "name": "GAR + 10-Formyl-THF => FGAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111338", "species_419151" ], "products": [ "species_70106", "species_111354", "species_111355" ], "modifiers": [ [ "species_10763376", "catalyst" ] ], "additional_components": [ "YGL234W" ] }, "reaction_10784783": { "compartment": "compartment_17951", "id": "reaction_10784783", "reactome": "R-SCE-6809808", "name": "ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6809801" ], "products": [ "species_6809800" ], "modifiers": [ [ "species_10784780", "catalyst" ] ], "additional_components": [ "P31787", "YGR037C" ] }, "reaction_10774954": { "compartment": "compartment_70101", "id": "reaction_10774954", "reactome": "R-SCE-3095901", "name": "ABCC1 transports cytosolic Cbl to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3000241", "species_29356" ], "products": [ "species_29370", "species_3000125", "species_29372" ], "modifiers": [ [ "species_10768249", "catalyst" ] ], "additional_components": [ "YDR135C" ] }, "reaction_10781339": { "compartment": "compartment_70616", "id": "reaction_10781339", "reactome": "R-SCE-5694137", "name": "PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693984", "species_113521", "species_159549" ], "products": [ "species_200671", "species_379732" ], "modifiers": [ [ "species_10781336", "catalyst" ] ], "additional_components": [ "P37291", "YLR058C", "P37292", "YBR263W" ] }, "reaction_10762043": { "compartment": "compartment_70101", "id": "reaction_10762043", "reactome": "R-SCE-71593", "name": "((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761992" ], "products": [ "species_70113", "species_10762040" ], "modifiers": [ [ "species_10761997", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_113527", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_113527", "P36143", "YKR058W", "YPR184W" ] }, "reaction_10769898": { "compartment": "compartment_70101", "id": "reaction_10769898", "reactome": "R-SCE-428676", "name": "sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203" ], "products": [ "species_428686", "species_428671" ], "modifiers": [ [ "species_10769895", "catalyst" ] ], "additional_components": [ "YDR294C" ] }, "reaction_10787703": { "compartment": "compartment_70101", "id": "reaction_10787703", "reactome": "R-SCE-8955844", "name": "RBKS phosphorylates ribose to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8955853" ], "products": [ "species_29370", "species_73578" ], "modifiers": [ [ "species_10787700", "catalyst" ] ], "additional_components": [ "YCR036W" ] }, "reaction_10773027": { "compartment": "compartment_12045", "id": "reaction_10773027", "reactome": "R-SCE-1482612", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10773044": { "compartment": "compartment_70101", "id": "reaction_10773044", "reactome": "R-SCE-1482656", "name": "PA is hydrolysed to 1-acyl LPA by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_1500604", "species_1524021" ], "modifiers": [ [ "species_10772999", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10766748": { "compartment": "compartment_70101", "id": "reaction_10766748", "reactome": "R-SCE-191382", "name": "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362" ], "products": [ "species_191324" ], "modifiers": [ [ "species_10766745", "catalyst" ] ], "additional_components": [ "P15496", "YPL117C", "species_109496" ] }, "reaction_10773106": { "compartment": "compartment_70616", "id": "reaction_10773106", "reactome": "R-SCE-1482759", "name": "MLCL is hydrolyzed to DLCL by PLA2G4A (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498773", "species_113521" ], "products": [ "species_1524085", "species_1498753" ], "modifiers": [ [ "species_10773103", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10784748": { "compartment": "compartment_876", "id": "reaction_10784748", "reactome": "R-SCE-6809325", "name": "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10784742", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10761813": { "compartment": "compartment_70101", "id": "reaction_10761813", "reactome": "R-SCE-71249", "name": "SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31503" ], "products": [ "species_29424", "species_31311" ], "modifiers": [ [ "species_10761810", "catalyst" ] ], "additional_components": [ "P37292", "YBR263W" ] }, "reaction_10785576": { "compartment": "compartment_528865", "id": "reaction_10785576", "reactome": "R-SCE-8851494", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851509", "species_8851517" ], "products": [ "species_8851518", "species_8851513", "species_5228597" ], "modifiers": [ [ "species_10785573", "catalyst" ] ], "additional_components": [ "species_29494", "species_29438", "species_110614", "species_29420", "species_110096", "species_110094", "P40009", "YER005W", "species_74016" ] }, "reaction_10767509": { "compartment": "compartment_70101", "id": "reaction_10767509", "reactome": "R-SCE-200676", "name": "MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200739" ], "products": [ "species_29366", "species_174404" ], "modifiers": [ [ "species_10767506", "catalyst" ] ], "additional_components": [ "P53128", "YGL125W" ] }, "reaction_10773109": { "compartment": "compartment_12045", "id": "reaction_10773109", "reactome": "R-SCE-1482771", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[9]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_29356" ], "products": [ "species_1498724", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10761833": { "compartment": "compartment_70101", "id": "reaction_10761833", "reactome": "R-SCE-71286", "name": "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_30401" ], "products": [ "species_70106", "species_71285", "species_29916" ], "modifiers": [ [ "species_10761830", "catalyst" ] ], "additional_components": [ "YDR465C" ] }, "reaction_10766996": { "compartment": "compartment_70101", "id": "reaction_10766996", "reactome": "R-SCE-196955", "name": "2xENPP1 hydrolyzes FAD to FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29386", "species_29356" ], "products": [ "species_73524", "species_76577" ], "modifiers": [ [ "species_10766993", "catalyst" ] ], "additional_components": [ "P39997", "YEL016C", "P25353", "YCR026C" ] }, "reaction_10775588": { "compartment": "compartment_70101", "id": "reaction_10775588", "reactome": "R-SCE-3322016", "name": "GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775576" ], "products": [ "species_10775586" ], "modifiers": [ [ "species_10775557", "catalyst" ] ], "additional_components": [ "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "YEL011W" ] }, "reaction_10766523": { "compartment": "compartment_70101", "id": "reaction_10766523", "reactome": "R-SCE-189406", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189464", "species_29356" ], "products": [ "species_189449", "species_31633" ], "modifiers": [ [ "species_10766520", "catalyst" ] ], "additional_components": [ "CHEBI:36319", "P28789", "YDL205C" ] }, "reaction_10775584": { "compartment": "compartment_70101", "id": "reaction_10775584", "reactome": "R-SCE-3322014", "name": "Autoglucosylation of GYG2 complexed with GYS2-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775581" ], "products": [ "species_110096", "species_10775574" ], "modifiers": [ [ "species_10775581", "catalyst" ] ], "additional_components": [ "P27472", "YLR258W", "P47011", "YJL137C", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P27472", "YLR258W", "P47011", "YJL137C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10767006": { "compartment": "compartment_70101", "id": "reaction_10767006", "reactome": "R-SCE-196964", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196931" ], "products": [ "species_29370", "species_73524" ], "modifiers": [ [ "species_10767003", "catalyst" ] ], "additional_components": [ "Q03778", "YDR236C", "species_109496" ] }, "reaction_10773229": { "compartment": "compartment_12045", "id": "reaction_10773229", "reactome": "R-SCE-1482976", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426955", "species_426910" ], "products": [ "species_109395", "species_426639" ], "modifiers": [ [ "species_10773226", "catalyst" ] ], "additional_components": [ "P06197", "YPR113W", "species_113527", "species_109496" ] }, "reaction_10787576": { "compartment": "compartment_984", "id": "reaction_10787576", "reactome": "R-SCE-8952251", "name": "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2173763", "species_109276" ], "products": [ "species_8952253", "species_8954142" ], "modifiers": [ [ "species_10787573", "catalyst" ] ], "additional_components": [ "YDR058C" ] }, "reaction_10761616": { "compartment": "compartment_5460", "id": "reaction_10761616", "reactome": "R-SCE-70724", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_508190" ], "products": [ "species_113552", "species_508181" ], "modifiers": [ [ "species_10761613", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "species_351964", "CHEBI:57762", "CHEBI:28654", "CHEBI:16530", "CHEBI:17865", "P47176", "YJR148W", "P38891", "YHR208W" ] }, "reaction_10778320": { "compartment": "compartment_70101", "id": "reaction_10778320", "reactome": "R-SCE-5652195", "name": "SORD oxidizes D-sorbitol to Fru", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_5652213" ], "products": [ "species_70106", "species_73473", "species_29532" ], "modifiers": [ [ "species_10778317", "catalyst" ] ], "additional_components": [ "Q07993", "YLR070C", "species_158417", "Q07786", "YDL246C", "P35497", "YJR159W" ] }, "reaction_10763347": { "compartment": "compartment_70101", "id": "reaction_10763347", "reactome": "R-SCE-73794", "name": "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29602", "species_29360", "species_29356" ], "products": [ "species_73473", "species_70106", "species_111584" ], "modifiers": [ [ "species_10763342", "catalyst" ], [ "species_10763345", "inhibitor" ], [ "species_111584", "inhibitor" ] ], "additional_components": [ "P38697", "YHR216W", "P50095", "YLR432W", "P50094", "YML056C", "P38697", "YHR216W", "P50095", "YLR432W", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842", "P50094", "YML056C" ] }, "reaction_10788488": { "compartment": "compartment_70101", "id": "reaction_10788488", "reactome": "R-SCE-9034539", "name": "PXLP-K56-SRR dimer deaminates L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_29382", "species_29398", "species_29356" ], "modifiers": [ [ "species_10788216", "catalyst" ] ], "additional_components": [ "P36007", "YKL218C" ] }, "reaction_10784328": { "compartment": "compartment_12045", "id": "reaction_10784328", "reactome": "R-SCE-6807053", "name": "SC5D desaturates LTHSOL to 7-dehydroCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_6807054", "species_29368" ], "products": [ "species_29366", "species_6807057", "species_29356" ], "modifiers": [ [ "species_10766920", "catalyst" ] ], "additional_components": [ "YLR056W" ] }, "reaction_10773042": { "compartment": "compartment_12045", "id": "reaction_10773042", "reactome": "R-SCE-1482646", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10773037", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10764110": { "compartment": "compartment_12045", "id": "reaction_10764110", "reactome": "R-SCE-75885", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500604", "species_1500578" ], "products": [ "species_76194", "species_426755" ], "modifiers": [ [ "species_10764107", "catalyst" ] ], "additional_components": [ "P33333", "YDL052C", "Q08750", "YOR298W", "P38226", "YBR042C" ] }, "reaction_10769889": { "compartment": "compartment_70101", "id": "reaction_10769889", "reactome": "R-SCE-428664", "name": "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428275", "species_29356" ], "products": [ "species_428694", "species_29372" ], "modifiers": [ [ "species_10769886", "catalyst" ] ], "additional_components": [ "P47013", "YJL134W", "P23501", "YKR053C" ] }, "reaction_10766913": { "compartment": "compartment_70101", "id": "reaction_10766913", "reactome": "R-SCE-194698", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194644" ], "products": [ "species_29366", "species_194633" ], "modifiers": [ [ "species_10766910", "catalyst" ] ], "additional_components": [ "YNL280C" ] }, "reaction_10773596": { "compartment": "compartment_20699", "id": "reaction_10773596", "reactome": "R-SCE-1676152", "name": "PI4KB binds to ARF1/3:GTP at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773594", "species_10773521" ], "products": [ "species_10773523" ], "modifiers": [], "additional_components": [ "YNL267W", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996", "P39104", "YNL267W", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10761653": { "compartment": "compartment_5460", "id": "reaction_10761653", "reactome": "R-SCE-70967", "name": "isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29938", "species_113526" ], "products": [ "species_113594", "species_29376", "species_29362", "species_113529" ], "modifiers": [ [ "species_10761650", "catalyst" ], [ "species_113581", "catalyst" ] ], "additional_components": [ "P28241", "YOR136W", "P28834", "IDH1", "species_113527" ] }, "reaction_10774302": { "compartment": "compartment_70101", "id": "reaction_10774302", "reactome": "R-SCE-2408551", "name": "SeMet is converted to AdoSeMet by MAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_5357707", "species_29356" ], "products": [ "species_5357652", "species_111294", "species_29372" ], "modifiers": [ [ "species_10766294", "catalyst" ] ], "additional_components": [ "P19358", "YDR502C", "species_74126", "species_109496", "P10659", "YLR180W" ] }, "reaction_10771159": { "compartment": "compartment_70101", "id": "reaction_10771159", "reactome": "R-SCE-548843", "name": "ACSL3,4 ligate CoA to AA to form AA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_29768", "species_113592" ], "products": [ "species_111294", "species_76577", "species_29356", "species_548819" ], "modifiers": [ [ "species_10771156", "catalyst" ] ], "additional_components": [ "P47912", "YMR246W", "P39002", "YIL009W", "P30624", "YOR317W" ] }, "reaction_10783830": { "compartment": "compartment_12045", "id": "reaction_10783830", "reactome": "R-SCE-6800334", "name": "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6800352", "species_1500578" ], "products": [ "species_76194", "species_76103" ], "modifiers": [ [ "species_10783823", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10773032": { "compartment": "compartment_12045", "id": "reaction_10773032", "reactome": "R-SCE-1482629", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10772937": { "compartment": "compartment_12045", "id": "reaction_10772937", "reactome": "R-SCE-1482539", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498740", "species_1500578" ], "products": [ "species_76194", "species_1483256" ], "modifiers": [ [ "species_10772934", "catalyst" ] ], "additional_components": [ "Q12185", "YDR018C", "P38226", "YBR042C" ] }, "reaction_10764651": { "compartment": "compartment_70101", "id": "reaction_10764651", "reactome": "R-SCE-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_6788782" ], "products": [ "species_113592", "species_6788778" ], "modifiers": [ [ "species_10764648", "catalyst" ] ], "additional_components": [ "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "species_109395", "species_76577", "species_109378", "species_109386", "P26364", "YER170W", "P07170", "YDR226W" ] }, "reaction_10763371": { "compartment": "compartment_70101", "id": "reaction_10763371", "reactome": "R-SCE-73800", "name": "SAICAR => AICAR + Fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111399" ], "products": [ "species_29586", "species_111409" ], "modifiers": [ [ "species_10763368", "catalyst" ] ], "additional_components": [ "Q05911", "YLR359W" ] }, "reaction_10773168": { "compartment": "compartment_12045", "id": "reaction_10773168", "reactome": "R-SCE-1482900", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498740", "species_1524021" ], "modifiers": [ [ "species_10772999", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10766900": { "compartment": "compartment_13231", "id": "reaction_10766900", "reactome": "R-SCE-194674", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194681", "species_194688", "species_194725" ], "products": [ "species_194704", "species_194668" ], "modifiers": [ [ "species_10766897", "catalyst" ] ], "additional_components": [ "YNL280C" ] }, "reaction_10772957": { "compartment": "compartment_12045", "id": "reaction_10772957", "reactome": "R-SCE-1482545", "name": "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_29356" ], "products": [ "species_1524023", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10775612": { "compartment": "compartment_70101", "id": "reaction_10775612", "reactome": "R-SCE-3322041", "name": "Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775533" ], "products": [ "species_10775609", "species_110096" ], "modifiers": [ [ "species_10775533", "catalyst" ], [ "species_30537", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10775536": { "compartment": "compartment_70101", "id": "reaction_10775536", "reactome": "R-SCE-3322003", "name": "Autoglucosylation of GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775531" ], "products": [ "species_110096", "species_10775533" ], "modifiers": [ [ "species_10775531", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P27472", "YLR258W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P27472", "YLR258W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10761781": { "compartment": "compartment_70101", "id": "reaction_10761781", "reactome": "R-SCE-71200", "name": "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_29368", "species_29970" ], "products": [ "species_29366", "species_29356", "species_34351" ], "modifiers": [ [ "species_10761778", "catalyst" ] ], "additional_components": [ "YBL098W" ] }, "reaction_10767519": { "compartment": "compartment_70101", "id": "reaction_10767519", "reactome": "R-SCE-200681", "name": "FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_200665" ], "products": [ "species_29370", "species_174404", "species_29372" ], "modifiers": [ [ "species_10767056", "catalyst" ] ], "additional_components": [ "YOR241W" ] }, "reaction_10761689": { "compartment": "compartment_5460", "id": "reaction_10761689", "reactome": "R-SCE-70982", "name": "Fumarate + H2O <=> (S)-Malate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113588" ], "products": [ "species_113544" ], "modifiers": [ [ "species_10761686", "catalyst" ] ], "additional_components": [ "P08417", "YPL262W" ] }, "reaction_10784728": { "compartment": "compartment_70101", "id": "reaction_10784728", "reactome": "R-SCE-6809254", "name": "MTMR8 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784722", "species_10784724" ], "products": [ "species_10784726" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10769851": { "compartment": "compartment_70101", "id": "reaction_10769851", "reactome": "R-SCE-428214", "name": "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428163", "species_113592" ], "products": [ "species_29370", "species_428275" ], "modifiers": [ [ "species_10769848", "catalyst" ] ], "additional_components": [ "Q12246", "YOR171C", "P47045", "TIM54", "Q06147", "YLR260W" ] }, "reaction_10773157": { "compartment": "compartment_12045", "id": "reaction_10773157", "reactome": "R-SCE-1482884", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10767738": { "compartment": "compartment_876", "id": "reaction_10767738", "reactome": "R-SCE-203613", "name": "depalmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767589" ], "products": [ "species_76168", "species_10767646" ], "modifiers": [ [ "species_10767735", "catalyst" ] ], "additional_components": [ "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_113596", "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_29870", "species_113596", "Q12354", "YLR118C" ] }, "reaction_10763944": { "compartment": "compartment_70101", "id": "reaction_10763944", "reactome": "R-SCE-75125", "name": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500006", "species_29370" ], "products": [ "species_113592", "species_500009" ], "modifiers": [ [ "species_10763053", "catalyst" ] ], "additional_components": [ "species_110096", "species_110094", "CHEBI:58593", "species_109395", "species_109378", "species_109402", "YKL024C" ] }, "reaction_10761637": { "compartment": "compartment_5460", "id": "reaction_10761637", "reactome": "R-SCE-70940", "name": "saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_30176" ], "products": [ "species_113556", "species_113552", "species_29362", "species_113529" ], "modifiers": [ [ "species_10761631", "catalyst" ] ], "additional_components": [ "P38999", "YNR050C" ] }, "reaction_10761851": { "compartment": "compartment_70101", "id": "reaction_10761851", "reactome": "R-SCE-71299", "name": "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_29996" ], "products": [ "species_70106", "species_29732", "species_29364", "species_113528" ], "modifiers": [ [ "species_10761848", "catalyst" ] ], "additional_components": [ "P38720", "YHR183W" ] }, "reaction_10773119": { "compartment": "compartment_70616", "id": "reaction_10773119", "reactome": "R-SCE-1482794", "name": "CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524079", "species_1524072" ], "products": [ "species_1524075", "species_1498773" ], "modifiers": [ [ "species_10773113", "catalyst" ] ], "additional_components": [] }, "reaction_10784773": { "compartment": "compartment_70101", "id": "reaction_10784773", "reactome": "R-SCE-6809778", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6809774", "species_29356" ], "products": [ "species_422529", "species_29372" ], "modifiers": [ [ "species_10784765", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10761717": { "compartment": "compartment_5460", "id": "reaction_10761717", "reactome": "R-SCE-70994", "name": "Succinate <=> Fumarate (with FAD redox reaction on enzyme)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113536" ], "products": [ "species_113588" ], "modifiers": [ [ "species_10761714", "catalyst" ] ], "additional_components": [ "P21801", "YLL041C", "Q00711", "YKL148C", "Q08749", "TIM18", "P33421", "YKL141W", "species_113596" ] }, "reaction_10764120": { "compartment": "compartment_70101", "id": "reaction_10764120", "reactome": "R-SCE-75887", "name": "Conversion of Glycerol to Glycerol-3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116", "species_113592" ], "products": [ "species_29370", "species_76114" ], "modifiers": [ [ "species_10764115", "catalyst" ] ], "additional_components": [ "YHL032C" ] }, "reaction_10763395": { "compartment": "compartment_70101", "id": "reaction_10763395", "reactome": "R-SCE-73828", "name": "adenylosuccinate => adenosine 5'-monophosphate + fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_35141" ], "products": [ "species_29586", "species_76577" ], "modifiers": [ [ "species_10763368", "catalyst" ] ], "additional_components": [ "Q05911", "YLR359W" ] }, "reaction_10767535": { "compartment": "compartment_70101", "id": "reaction_10767535", "reactome": "R-SCE-200735", "name": "SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_197969" ], "products": [ "species_29424", "species_200739" ], "modifiers": [ [ "species_10761810", "catalyst" ] ], "additional_components": [ "P37292", "YBR263W" ] }, "reaction_10773035": { "compartment": "compartment_12045", "id": "reaction_10773035", "reactome": "R-SCE-1482635", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498730", "species_1500578" ], "products": [ "species_76194", "species_1483256" ], "modifiers": [ [ "species_10772934", "catalyst" ] ], "additional_components": [ "Q12185", "YDR018C", "P38226", "YBR042C" ] }, "reaction_10767447": { "compartment": "compartment_70101", "id": "reaction_10767447", "reactome": "R-SCE-200423", "name": "pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767435", "species_113592" ], "products": [ "species_29370", "species_10767442" ], "modifiers": [ [ "species_10767444", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527", "Q00955", "YNR016C", "species_113527", "P34164", "YGL208W", "Q04739", "YER027C", "P32578", "YDR422C", "P12904", "YGL115W", "P38845", "YHR146W", "P06782", "YDR477W", "P53885", "YNL173C" ] }, "reaction_10761230": { "compartment": "compartment_70101", "id": "reaction_10761230", "reactome": "R-SCE-70427", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29548" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10761125", "catalyst" ] ], "additional_components": [ "Q03262", "YMR278W", "species_109496" ] }, "reaction_10773584": { "compartment": "compartment_171062", "id": "reaction_10773584", "reactome": "R-SCE-1676141", "name": "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_1806199", "species_29372" ], "modifiers": [ [ "species_10773463", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10773458": { "compartment": "compartment_876", "id": "reaction_10773458", "reactome": "R-SCE-1675780", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_392417" ], "modifiers": [ [ "species_10773453", "catalyst" ] ], "additional_components": [ "YJL100W" ] }, "reaction_10786908": { "compartment": "compartment_70101", "id": "reaction_10786908", "reactome": "R-SCE-8876789", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6786250", "species_71284" ], "products": [ "species_71285", "species_8876775" ], "modifiers": [ [ "species_10786905", "catalyst" ] ], "additional_components": [ "YNL092W" ] }, "reaction_10767466": { "compartment": "compartment_5460", "id": "reaction_10767466", "reactome": "R-SCE-200474", "name": "NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8938083", "species_113593" ], "products": [ "species_8938090", "species_159450" ], "modifiers": [ [ "species_10767463", "catalyst" ] ], "additional_components": [ "Q06178", "YLR328W", "P53204", "YGR010W", "species_109496" ] }, "reaction_10762169": { "compartment": "compartment_70101", "id": "reaction_10762169", "reactome": "R-SCE-71735", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_113592", "species_29416" ], "products": [ "species_111294", "species_76577", "species_76183" ], "modifiers": [ [ "species_10762166", "catalyst" ] ], "additional_components": [ "P52910", "YLR153C", "Q01574", "YAL054C" ] }, "reaction_10784745": { "compartment": "compartment_876", "id": "reaction_10784745", "reactome": "R-SCE-6809320", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806240", "species_29372" ], "modifiers": [ [ "species_10784742", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10776275": { "compartment": "compartment_70101", "id": "reaction_10776275", "reactome": "R-SCE-3781023", "name": "PPP1R3C binds to glycogen:GYG1:GYS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775552", "species_10776211" ], "products": [ "species_10776273" ], "modifiers": [], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P40036", "YER054C", "Q06216", "YLR273C", "P28006", "YOR178C", "P40187", "YIL045W", "P40036", "YER054C", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10773161": { "compartment": "compartment_12045", "id": "reaction_10773161", "reactome": "R-SCE-1482892", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10767321": { "compartment": "compartment_70101", "id": "reaction_10767321", "reactome": "R-SCE-199803", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10761868", "catalyst" ] ], "additional_components": [ "P46969", "YJL121C", "species_111793" ] }, "reaction_10776271": { "compartment": "compartment_70101", "id": "reaction_10776271", "reactome": "R-SCE-3781018", "name": "EPM2A dimer dephosphorylates phosphoglycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10776268" ], "products": [ "species_10776261", "species_29372" ], "modifiers": [ [ "species_10776268", "catalyst" ] ], "additional_components": [ "P40187", "YIL045W", "P46958", "YJL146W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P46958", "YJL146W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P46958", "YJL146W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10770915": { "compartment": "compartment_70101", "id": "reaction_10770915", "reactome": "R-SCE-453338", "name": "PGYM b dimer:AMP complex <=> PGYM dimer, b form + 2 AMP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770913" ], "products": [ "species_10761929", "species_76577" ], "modifiers": [], "additional_components": [ "P06738", "YPR160W", "species_76577", "P06738", "YPR160W" ] }, "reaction_10781323": { "compartment": "compartment_70101", "id": "reaction_10781323", "reactome": "R-SCE-5694071", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_5694074" ], "products": [ "species_5694130" ], "modifiers": [ [ "species_10781320", "catalyst" ] ], "additional_components": [ "species_158417", "P50107", "YML004C" ] }, "reaction_10773592": { "compartment": "compartment_876", "id": "reaction_10773592", "reactome": "R-SCE-1676149", "name": "PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_202247", "species_29356" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10767316", "catalyst" ] ], "additional_components": [ "YNL128W" ] }, "reaction_10769915": { "compartment": "compartment_984", "id": "reaction_10769915", "reactome": "R-SCE-428690", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419305", "species_109276" ], "products": [ "species_109277", "species_428662" ], "modifiers": [ [ "species_10769912", "catalyst" ] ], "additional_components": [ "Q05521", "YDR284C", "Q04396", "YDR503C" ] }, "reaction_10774502": { "compartment": "compartment_70101", "id": "reaction_10774502", "reactome": "R-SCE-2509827", "name": "ITPA hydrolyses ITP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2509836" ], "products": [ "species_70106", "species_29602", "species_111294" ], "modifiers": [ [ "species_10774499", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P47119", "YJR069C" ] }, "reaction_10773490": { "compartment": "compartment_20699", "id": "reaction_10773490", "reactome": "R-SCE-1675824", "name": "PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806165", "species_29356" ], "products": [ "species_1806217", "species_29372" ], "modifiers": [ [ "species_10773487", "catalyst" ] ], "additional_components": [ "YOL065C" ] }, "reaction_10773049": { "compartment": "compartment_12045", "id": "reaction_10773049", "reactome": "R-SCE-1482685", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10781088": { "compartment": "compartment_70101", "id": "reaction_10781088", "reactome": "R-SCE-5692283", "name": "ALD3A1 oxidises 4HPCP to CXPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5692409", "species_29366", "species_29356" ], "products": [ "species_70106", "species_29364", "species_5692433" ], "modifiers": [ [ "species_10781085", "catalyst" ] ], "additional_components": [ "YMR110C" ] }, "reaction_10774505": { "compartment": "compartment_70101", "id": "reaction_10774505", "reactome": "R-SCE-2509831", "name": "ITPA hydrolyses XTP to XMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509848", "species_29356" ], "products": [ "species_70106", "species_111584", "species_111294" ], "modifiers": [ [ "species_10774499", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P47119", "YJR069C" ] }, "reaction_10766958": { "compartment": "compartment_70101", "id": "reaction_10766958", "reactome": "R-SCE-196761", "name": "2xTPK1:Mg2+ phosphorylates THMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196934" ], "products": [ "species_29480", "species_76577" ], "modifiers": [ [ "species_10766955", "catalyst" ] ], "additional_components": [ "P35202", "YOR143C", "species_109496" ] }, "reaction_10784761": { "compartment": "compartment_171062", "id": "reaction_10784761", "reactome": "R-SCE-6809720", "name": "PI3P is dephosphorylated to PI by MTM1:MTMR12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_1806199", "species_29372" ], "modifiers": [ [ "species_10784752", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10764851": { "compartment": "compartment_70101", "id": "reaction_10764851", "reactome": "R-SCE-111524", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29602", "species_29438", "species_29448" ], "products": [ "species_70106", "species_35141", "species_29372", "species_29420" ], "modifiers": [ [ "species_10764848", "catalyst" ], [ "species_29420", "inhibitor" ], [ "species_113578", "inhibitor" ], [ "species_35141", "inhibitor" ], [ "species_30014", "inhibitor" ] ], "additional_components": [ "P80210", "YNL220W", "species_109496" ] }, "reaction_10786559": { "compartment": "compartment_70101", "id": "reaction_10786559", "reactome": "R-SCE-8869627", "name": "NMRK2 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_70106", "species_29370", "species_8869353" ], "modifiers": [ [ "species_10786553", "catalyst" ] ], "additional_components": [ "YNL129W" ] }, "reaction_10761438": { "compartment": "compartment_5460", "id": "reaction_10761438", "reactome": "R-SCE-70542", "name": "glutamate + acetyl CoA => N-acetyl glutamate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113559" ], "products": [ "species_29374", "species_30471" ], "modifiers": [ [ "species_10761435", "catalyst" ], [ "species_374064", "catalyst" ] ], "additional_components": [ "YER069W" ] }, "reaction_10773539": { "compartment": "compartment_171062", "id": "reaction_10773539", "reactome": "R-SCE-1675974", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806180" ], "modifiers": [ [ "species_10773453", "catalyst" ] ], "additional_components": [ "YJL100W" ] }, "reaction_10773138": { "compartment": "compartment_70616", "id": "reaction_10773138", "reactome": "R-SCE-1482847", "name": "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524085", "species_1524047" ], "modifiers": [ [ "species_10773088", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10770921": { "compartment": "compartment_70101", "id": "reaction_10770921", "reactome": "R-SCE-453339", "name": "poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762038", "species_29372" ], "products": [ "species_10770919", "species_29548" ], "modifiers": [ [ "species_10762009", "catalyst" ] ], "additional_components": [ "P47011", "YJL137C", "species_113527", "P47011", "YJL137C", "species_113527", "P06738", "YPR160W" ] }, "reaction_10761311": { "compartment": "compartment_70101", "id": "reaction_10761311", "reactome": "R-SCE-70467", "name": "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_29370", "species_30014" ], "modifiers": [ [ "species_10761308", "catalyst" ], [ "species_30533", "catalyst" ], [ "species_29370", "catalyst" ], [ "species_76577", "catalyst" ], [ "species_113592", "inhibitor" ], [ "species_76190", "inhibitor" ] ], "additional_components": [ "P16861", "YGR240C", "P16862", "YMR205C" ] }, "reaction_10766705": { "compartment": "compartment_70101", "id": "reaction_10766705", "reactome": "R-SCE-191322", "name": "FDPS dimer transfers IPPP to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191324" ], "products": [ "species_191409", "species_111294" ], "modifiers": [ [ "species_10766699", "catalyst" ] ], "additional_components": [ "P08524", "YJL167W", "species_109496" ] }, "reaction_10772005": { "compartment": "compartment_70101", "id": "reaction_10772005", "reactome": "R-SCE-965079", "name": "2xPNPO:2xFMN oxidizes PXAP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965146", "species_29368", "species_29356" ], "products": [ "species_29408", "species_31633", "species_29390" ], "modifiers": [ [ "species_10772000", "catalyst" ] ], "additional_components": [ "species_73524", "P38075", "YBR035C" ] }, "reaction_10764030": { "compartment": "compartment_70101", "id": "reaction_10764030", "reactome": "R-SCE-75849", "name": "Transport of Citrate from Mitochondrial Matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29654", "species_198498" ], "products": [ "species_76190", "species_113544" ], "modifiers": [ [ "species_10764027", "catalyst" ] ], "additional_components": [ "YBR291C" ] }, "reaction_10771299": { "compartment": "compartment_70101", "id": "reaction_10771299", "reactome": "R-SCE-888614", "name": "IDO2 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29500" ], "products": [ "species_33179" ], "modifiers": [ [ "species_10771296", "catalyst" ] ], "additional_components": [ "P47125", "YJR078W", "species_189444" ] }, "reaction_10768921": { "compartment": "compartment_17951", "id": "reaction_10768921", "reactome": "R-SCE-389609", "name": "ALDH3A2-2 oxidizes pristanal to pristanate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389636", "species_192307" ], "products": [ "species_193465", "species_6811612", "species_192305" ], "modifiers": [ [ "species_10768918", "catalyst" ] ], "additional_components": [ "Q04458", "YMR110C" ] }, "reaction_10767051": { "compartment": "compartment_70101", "id": "reaction_10767051", "reactome": "R-SCE-197271", "name": "NADSYN1 hexamer amidates NAAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197256", "species_29472", "species_113592", "species_29356" ], "products": [ "species_29404", "species_111294", "species_29360", "species_76577" ], "modifiers": [ [ "species_10767048", "catalyst" ] ], "additional_components": [ "P38795", "YHR074W" ] }, "reaction_10767059": { "compartment": "compartment_70101", "id": "reaction_10767059", "reactome": "R-SCE-197958", "name": "FPGS-2 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_111355" ], "products": [ "species_29370", "species_197969", "species_29372" ], "modifiers": [ [ "species_10767056", "catalyst" ] ], "additional_components": [ "YOR241W" ] }, "reaction_10763076": { "compartment": "compartment_70101", "id": "reaction_10763076", "reactome": "R-SCE-73577", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_111627", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_29372", "species_111647" ], "modifiers": [ [ "species_10763067", "catalyst" ] ], "additional_components": [ "P07259", "YJL130C", "P03965", "YJR109C" ] }, "reaction_10766605": { "compartment": "compartment_70101", "id": "reaction_10766605", "reactome": "R-SCE-190182", "name": "UROD decarboxylates URO1 to COPRO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190157" ], "products": [ "species_113528", "species_190128" ], "modifiers": [ [ "species_10766550", "catalyst" ] ], "additional_components": [ "P32347", "YDR047W" ] }, "reaction_10766872": { "compartment": "compartment_70101", "id": "reaction_10766872", "reactome": "R-SCE-193961", "name": "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196366" ], "products": [ "species_193092" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10773558": { "compartment": "compartment_172574", "id": "reaction_10773558", "reactome": "R-SCE-1676065", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806289" ], "products": [ "species_1806212", "species_29372" ], "modifiers": [ [ "species_10773463", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10773091": { "compartment": "compartment_70616", "id": "reaction_10773091", "reactome": "R-SCE-1482745", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524085", "species_1524027" ], "modifiers": [ [ "species_10773088", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10784326": { "compartment": "compartment_5460", "id": "reaction_10784326", "reactome": "R-SCE-6806967", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807477", "species_113593" ], "products": [ "species_113548", "species_113600", "species_113581", "species_113529" ], "modifiers": [ [ "species_10784323", "catalyst" ] ], "additional_components": [ "YKL151C" ] }, "reaction_10761600": { "compartment": "compartment_70101", "id": "reaction_10761600", "reactome": "R-SCE-70723", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_508182", "species_29406" ], "products": [ "species_29404", "species_508187" ], "modifiers": [ [ "species_10761597", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "species_351964", "CHEBI:57762", "CHEBI:28654", "CHEBI:16530", "CHEBI:17865", "P38891", "YHR208W" ] }, "reaction_10773166": { "compartment": "compartment_12045", "id": "reaction_10773166", "reactome": "R-SCE-1482897", "name": "PS is hydrolyzed to 2-acyl LPS by PLA2[10]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_29356" ], "products": [ "species_1498722", "species_1524021" ], "modifiers": [ [ "species_10773124", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10763142": { "compartment": "compartment_70101", "id": "reaction_10763142", "reactome": "R-SCE-73605", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109382", "species_111355" ], "products": [ "species_109366", "species_73604" ], "modifiers": [ [ "species_10763139", "catalyst" ] ], "additional_components": [ "P06785", "YOR074C", "species_109496" ] }, "reaction_10767724": { "compartment": "compartment_20699", "id": "reaction_10767724", "reactome": "R-SCE-203567", "name": "palmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767644", "species_200993" ], "products": [ "species_10767716" ], "modifiers": [ [ "species_10767721", "catalyst" ] ], "additional_components": [ "YHR042W", "YHR042W", "YLR246W" ] }, "reaction_10767524": { "compartment": "compartment_5460", "id": "reaction_10767524", "reactome": "R-SCE-200682", "name": "Mitochondrial FPGS-1 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_200671", "species_113593" ], "products": [ "species_113548", "species_200679", "species_113581" ], "modifiers": [ [ "species_10767521", "catalyst" ] ], "additional_components": [ "YOR241W" ] }, "reaction_10763403": { "compartment": "compartment_5460", "id": "reaction_10763403", "reactome": "R-SCE-73918", "name": "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73871", "species_113559" ], "products": [ "species_29374", "species_73917" ], "modifiers": [ [ "species_10763400", "catalyst" ] ], "additional_components": [ "YML126C" ] }, "reaction_10785542": { "compartment": "compartment_984", "id": "reaction_10785542", "reactome": "R-SCE-8851110", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785539", "catalyst" ] ], "additional_components": [ "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10773526": { "compartment": "compartment_20699", "id": "reaction_10773526", "reactome": "R-SCE-1675883", "name": "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10773523", "catalyst" ] ], "additional_components": [ "P39104", "YNL267W", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10770990": { "compartment": "compartment_70101", "id": "reaction_10770990", "reactome": "R-SCE-482619", "name": "(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_482627", "species_113592" ], "products": [ "species_29370", "species_482625" ], "modifiers": [ [ "species_10770987", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:60471", "CHEBI:58369", "CHEBI:58595", "CHEBI:57667", "species_110096", "species_110094", "CHEBI:58593", "species_29494", "species_500739", "species_29892", "species_110644", "species_30185", "species_30187", "species_29438", "species_110614", "P36010", "YKL067W" ] }, "reaction_10769859": { "compartment": "compartment_70101", "id": "reaction_10769859", "reactome": "R-SCE-428262", "name": "phytoceramide + H2O => stearate + phytosphingosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025544", "species_29356" ], "products": [ "species_3632878", "species_428237" ], "modifiers": [ [ "species_10769856", "catalyst" ] ], "additional_components": [ "YPL087W" ] }, "reaction_10776266": { "compartment": "compartment_70101", "id": "reaction_10776266", "reactome": "R-SCE-3781011", "name": "EPM2A dimer dephosphorylates phosphoglycogen-GYG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10776263" ], "products": [ "species_10776227", "species_29372" ], "modifiers": [ [ "species_10776263", "catalyst" ] ], "additional_components": [ "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10767041": { "compartment": "compartment_70101", "id": "reaction_10767041", "reactome": "R-SCE-197268", "name": "QPRT transfers PRIB to QUIN to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73566", "species_197238" ], "products": [ "species_113528", "species_111294", "species_197220" ], "modifiers": [ [ "species_10767038", "catalyst" ] ], "additional_components": [ "YFR047C" ] }, "reaction_10785578": { "compartment": "compartment_984", "id": "reaction_10785578", "reactome": "R-SCE-8851538", "name": "NTPDase8 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9726184", "species_109276" ], "products": [ "species_9726189", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785532", "catalyst" ] ], "additional_components": [ "species_29494", "species_30187", "species_113592", "species_2509836", "species_29438", "species_110614", "species_29420", "CHEBI:58369", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10774297": { "compartment": "compartment_5460", "id": "reaction_10774297", "reactome": "R-SCE-2395512", "name": "FDXR transfers electrons to FDX1,2 (FDX1L)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774293", "species_10772859" ], "products": [ "species_10772851", "species_10774295", "species_113529" ], "modifiers": [], "additional_components": [ "P48360", "YDR376W", "species_31649", "CHEBI:33737", "Q12184", "YPL252C", "CHEBI:33738", "Q12184", "YPL252C", "P48360", "YDR376W", "species_113596" ] }, "reaction_10771310": { "compartment": "compartment_70101", "id": "reaction_10771310", "reactome": "R-SCE-893593", "name": "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29502", "species_29398" ], "products": [ "species_893599", "species_29432" ], "modifiers": [ [ "species_10771307", "catalyst" ] ], "additional_components": [ "P47039", "YJL060W" ] }, "reaction_10781200": { "compartment": "compartment_70101", "id": "reaction_10781200", "reactome": "R-SCE-5693390", "name": "HSD17B11 dehydrogenates EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_193132" ], "products": [ "species_70106", "species_29364", "species_193066" ], "modifiers": [ [ "species_10781197", "catalyst" ] ], "additional_components": [ "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C" ] }, "reaction_10773448": { "compartment": "compartment_876", "id": "reaction_10773448", "reactome": "R-SCE-1675776", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806240" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10773445", "catalyst" ] ], "additional_components": [ "P38994", "YDR208W" ] }, "reaction_10787145": { "compartment": "compartment_70101", "id": "reaction_10787145", "reactome": "R-SCE-8939959", "name": "NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869353" ], "products": [ "species_111294", "species_29360" ], "modifiers": [ [ "species_10767030", "catalyst" ] ], "additional_components": [ "Q06178", "YLR328W", "P53204", "YGR010W", "species_109496" ] }, "reaction_10788787": { "compartment": "compartment_70101", "id": "reaction_10788787", "reactome": "R-SCE-9638127", "name": "PGM1:Mg2+ isomerises G6P to G1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537" ], "products": [ "species_29548" ], "modifiers": [ [ "species_10788782", "catalyst" ] ], "additional_components": [ "P33401", "YKL127W", "species_109496" ] }, "reaction_10784736": { "compartment": "compartment_17951", "id": "reaction_10784736", "reactome": "R-SCE-6809287", "name": "NUDT12 hydrolyses NADH to NMNH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389620", "species_141343", "species_192305" ], "products": [ "species_6809289", "species_193465" ], "modifiers": [ [ "species_10784733", "catalyst" ] ], "additional_components": [ "YGL067W" ] }, "reaction_10767473": { "compartment": "compartment_7660", "id": "reaction_10767473", "reactome": "R-SCE-200512", "name": "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_200492" ], "products": [ "species_200499", "species_113541" ], "modifiers": [ [ "species_10767470", "catalyst" ] ], "additional_components": [ "species_158417", "Q06178", "YLR328W" ] }, "reaction_10773601": { "compartment": "compartment_876", "id": "reaction_10773601", "reactome": "R-SCE-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10773598", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "P50942", "YNL106C" ] }, "reaction_10774843": { "compartment": "compartment_70101", "id": "reaction_10774843", "reactome": "R-SCE-2993814", "name": "HLCS biotinylates ACACA:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_113592", "species_10774841" ], "products": [ "species_10764051", "species_111294", "species_76577" ], "modifiers": [ [ "species_10774830", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527", "P32874", "YMR207C", "Q00955", "YNR016C", "species_113527", "P32874", "YMR207C", "YDL141W" ] }, "reaction_10771961": { "compartment": "compartment_70101", "id": "reaction_10771961", "reactome": "R-SCE-947514", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_10771945" ], "products": [ "species_10771950", "species_29432" ], "modifiers": [ [ "species_10771958", "catalyst" ] ], "additional_components": [ "species_158417", "P38820", "YHR111W", "species_158417", "P38820", "YHR111W", "P25374", "YCL017C" ] }, "reaction_10773561": { "compartment": "compartment_876", "id": "reaction_10773561", "reactome": "R-SCE-1676082", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10773418", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10774121": { "compartment": "compartment_17951", "id": "reaction_10774121", "reactome": "R-SCE-2066779", "name": "Conversion of DHA-CoA to docosahexaenoic acid (DHA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_2066765" ], "products": [ "species_193514", "species_2066763" ], "modifiers": [ [ "species_10766854", "catalyst" ] ], "additional_components": [ "YJR019C" ] }, "reaction_10773542": { "compartment": "compartment_876", "id": "reaction_10773542", "reactome": "R-SCE-1675988", "name": "PI4P is dephosphorylated to PI by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_392417" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10773511", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "Q08227", "YOL065C", "P50942", "YNL106C" ] }, "reaction_10762104": { "compartment": "compartment_70101", "id": "reaction_10762104", "reactome": "R-SCE-71691", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29510", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_29416" ], "modifiers": [ [ "species_10762101", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10769022": { "compartment": "compartment_17951", "id": "reaction_10769022", "reactome": "R-SCE-389862", "name": "Conversion of glyoxylate to oxalate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389678", "species_141343", "species_113535" ], "products": [ "species_389819", "species_113575" ], "modifiers": [ [ "species_10769016", "catalyst" ] ], "additional_components": [ "species_73524", "P00175", "CYB2" ] }, "reaction_10767564": { "compartment": "compartment_70101", "id": "reaction_10767564", "reactome": "R-SCE-201035", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_3632881", "species_113592" ], "products": [ "species_111294", "species_76577", "species_29356", "species_200993" ], "modifiers": [ [ "species_10767561", "catalyst" ] ], "additional_components": [ "P47912", "YMR246W", "P39002", "YIL009W", "P30624", "YOR317W", "P39518", "YER015W" ] }, "reaction_10761112": { "compartment": "compartment_70101", "id": "reaction_10761112", "reactome": "R-SCE-70262", "name": "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30533", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10761109", "catalyst" ] ], "additional_components": [ "P32604", "YJL155C" ] }, "reaction_10768062": { "compartment": "compartment_70101", "id": "reaction_10768062", "reactome": "R-SCE-209792", "name": "N-acetylation of serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183", "species_209914" ], "products": [ "species_76194", "species_209793" ], "modifiers": [ [ "species_10768059", "catalyst" ] ], "additional_components": [ "YDR071C" ] }, "reaction_10774508": { "compartment": "compartment_70101", "id": "reaction_10774508", "reactome": "R-SCE-2509838", "name": "ITPA hydrolyses dITP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509835", "species_29356" ], "products": [ "species_70106", "species_9731659", "species_111294" ], "modifiers": [ [ "species_10774499", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P47119", "YJR069C" ] }, "reaction_10785581": { "compartment": "compartment_984", "id": "reaction_10785581", "reactome": "R-SCE-8851550", "name": "NTPDase8 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9726189", "species_109276" ], "products": [ "species_109277", "species_351626", "species_9726186" ], "modifiers": [ [ "species_10785532", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58369", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "species_109366", "species_109395", "species_29602", "species_76577", "species_109402", "species_113578", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10761792": { "compartment": "compartment_70101", "id": "reaction_10761792", "reactome": "R-SCE-71217", "name": "3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_34351" ], "products": [ "species_30487", "species_29432" ], "modifiers": [ [ "species_10761789", "catalyst" ] ], "additional_components": [ "Q05979", "YLR231C" ] }, "reaction_10763309": { "compartment": "compartment_70101", "id": "reaction_10763309", "reactome": "R-SCE-73788", "name": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500071", "species_113592" ], "products": [ "species_500077", "species_29370" ], "modifiers": [ [ "species_10763306", "catalyst" ] ], "additional_components": [ "CHEBI:57673", "species_113578", "species_29420", "CHEBI:58595", "YDR454C" ] }, "reaction_10766758": { "compartment": "compartment_70101", "id": "reaction_10766758", "reactome": "R-SCE-191402", "name": "Reduction of presqualene diphosphate to form squalene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_191265", "species_29364" ], "products": [ "species_29366", "species_191269", "species_111294" ], "modifiers": [ [ "species_10766755", "catalyst" ] ], "additional_components": [ "P29704", "YHR190W", "species_109496" ] }, "reaction_10766487": { "compartment": "compartment_5460", "id": "reaction_10766487", "reactome": "R-SCE-188467", "name": "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_188458" ], "products": [ "species_188451", "species_31649" ], "modifiers": [ [ "species_10766484", "catalyst" ] ], "additional_components": [ "YIL155C" ] }, "reaction_10781600": { "compartment": "compartment_70101", "id": "reaction_10781600", "reactome": "R-SCE-5694583", "name": "ABHD4 hydrolyses NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694568" ], "products": [ "species_5694580", "species_5694567" ], "modifiers": [ [ "species_10781597", "catalyst" ] ], "additional_components": [ "Q12385", "YLR099C", "Q04623", "YDR125C", "P53264", "YGR110W", "P53208", "YGR015C" ] }, "reaction_10773609": { "compartment": "compartment_876", "id": "reaction_10773609", "reactome": "R-SCE-1676203", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806240", "species_29372" ], "modifiers": [ [ "species_10773550", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "P47147", "YJR110W", "P50942", "YNL106C" ] }, "reaction_10764056": { "compartment": "compartment_70101", "id": "reaction_10764056", "reactome": "R-SCE-75851", "name": "Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10764053", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527", "P32874", "YMR207C" ] }, "reaction_10771185": { "compartment": "compartment_70101", "id": "reaction_10771185", "reactome": "R-SCE-549192", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76103", "species_75967" ], "products": [ "species_76194", "species_549167" ], "modifiers": [ [ "species_10771182", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10763172": { "compartment": "compartment_7660", "id": "reaction_10763172", "reactome": "R-SCE-73666", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_500739" ], "products": [ "species_113541", "species_500742", "species_9668967" ], "modifiers": [ [ "species_10763169", "catalyst" ] ], "additional_components": [ "P33317", "YBR252W" ] }, "reaction_10761773": { "compartment": "compartment_70101", "id": "reaction_10761773", "reactome": "R-SCE-71146", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71112" ], "products": [ "species_29356", "species_71129" ], "modifiers": [ [ "species_10761770", "catalyst" ] ], "additional_components": [ "P38744", "YHL018W" ] }, "reaction_10773002": { "compartment": "compartment_17906", "id": "reaction_10773002", "reactome": "R-SCE-1482604", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590", "species_29356" ], "products": [ "species_1524103", "species_1500580" ], "modifiers": [ [ "species_10772999", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10764827": { "compartment": "compartment_70101", "id": "reaction_10764827", "reactome": "R-SCE-111215", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_110644" ], "products": [ "species_73566", "species_109386" ], "modifiers": [ [ "species_10763105", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_29372", "catalyst" ] ], "additional_components": [ "P38063", "YBL068W", "P32895", "YKL181W", "P38689", "YHL011C", "Q12265", "YOL061W", "P38620", "YER099C" ] }, "reaction_10774851": { "compartment": "compartment_5460", "id": "reaction_10774851", "reactome": "R-SCE-2995330", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_2162257", "species_189444" ], "products": [ "species_2995328", "species_159450" ], "modifiers": [ [ "species_10774848", "catalyst" ] ], "additional_components": [ "YPL172C" ] }, "reaction_10761624": { "compartment": "compartment_5460", "id": "reaction_10761624", "reactome": "R-SCE-70881", "name": "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71847", "species_113521" ], "products": [ "species_29374", "species_573404" ], "modifiers": [ [ "species_10761621", "catalyst" ] ], "additional_components": [ "YDR036C" ] }, "reaction_10767280": { "compartment": "compartment_70101", "id": "reaction_10767280", "reactome": "R-SCE-198824", "name": "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10767267" ], "products": [ "species_29360", "species_10767269" ], "modifiers": [ [ "species_10767277", "catalyst" ] ], "additional_components": [ "CHEBI:36144", "P40312", "YNL111C", "species_189444", "P40312", "YNL111C", "P38626", "YIL043C", "species_113596" ] }, "reaction_10785569": { "compartment": "compartment_984", "id": "reaction_10785569", "reactome": "R-SCE-8851396", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851462", "species_109276" ], "products": [ "species_109277", "species_351626", "species_8851461" ], "modifiers": [ [ "species_10785566", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58280", "species_110094", "species_110096", "species_109395", "species_29602", "species_109402", "species_113578", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10774119": { "compartment": "compartment_17951", "id": "reaction_10774119", "reactome": "R-SCE-2066778", "name": "Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2066767", "species_141343" ], "products": [ "species_2066766" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10787695": { "compartment": "compartment_5460", "id": "reaction_10787695", "reactome": "R-SCE-8955817", "name": "PRODH2 oxidises HPRO to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784215", "species_113597" ], "products": [ "species_164934", "species_113521", "species_113590" ], "modifiers": [ [ "species_10781897", "catalyst" ] ], "additional_components": [ "YLR142W" ] }, "reaction_10772003": { "compartment": "compartment_70101", "id": "reaction_10772003", "reactome": "R-SCE-965019", "name": "2xPNPO:2xFMN oxidizes PDXP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964952", "species_29368" ], "products": [ "species_29408", "species_29390" ], "modifiers": [ [ "species_10772000", "catalyst" ] ], "additional_components": [ "species_73524", "P38075", "YBR035C" ] }, "reaction_10771152": { "compartment": "compartment_70101", "id": "reaction_10771152", "reactome": "R-SCE-548831", "name": "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_548809" ], "products": [ "species_29366", "species_428139" ], "modifiers": [ [ "species_10771147", "catalyst" ] ], "additional_components": [ "YDL015C" ] }, "reaction_10761763": { "compartment": "compartment_5460", "id": "reaction_10761763", "reactome": "R-SCE-71037", "name": "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113526", "species_70951" ], "products": [ "species_70955", "species_29376", "species_29362" ], "modifiers": [ [ "species_10761760", "catalyst" ] ], "additional_components": [ "species_29480", "P20967", "YIL125W", "CHEBI:17460", "P09624", "YFL018C", "species_113596", "P19262", "YDR148C" ] }, "reaction_10767016": { "compartment": "compartment_70101", "id": "reaction_10767016", "reactome": "R-SCE-197198", "name": "NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29360" ], "products": [ "species_29370", "species_29366" ], "modifiers": [ [ "species_10767013", "catalyst" ] ], "additional_components": [ "species_158417", "P21373", "YJR049C" ] }, "reaction_10784758": { "compartment": "compartment_70101", "id": "reaction_10784758", "reactome": "R-SCE-6809707", "name": "MTMR12 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784750", "species_10773465" ], "products": [ "species_10784756" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10782032": { "compartment": "compartment_7660", "id": "reaction_10782032", "reactome": "R-SCE-6788810", "name": "AK6 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788813", "species_29358" ], "products": [ "species_113582", "species_6788807" ], "modifiers": [ [ "species_10782029", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "YDL166C" ] }, "reaction_10768262": { "compartment": "compartment_70101", "id": "reaction_10768262", "reactome": "R-SCE-266072", "name": "LTA4 is hydolysed to LTB4 by LTA4H", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265281", "species_29356" ], "products": [ "species_266056" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10787954": { "compartment": "compartment_5460", "id": "reaction_10787954", "reactome": "R-SCE-9012016", "name": "FAHD1:Zn2+ dimer hydrolyses OA to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587" ], "products": [ "species_29376", "species_113557" ], "modifiers": [ [ "species_10787951", "catalyst" ] ], "additional_components": [ "P53889", "YNL168C", "species_109496" ] }, "reaction_10784681": { "compartment": "compartment_70101", "id": "reaction_10784681", "reactome": "R-SCE-6808496", "name": "ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_111353", "species_29356" ], "products": [ "species_70106", "species_29364", "species_113528", "species_197969" ], "modifiers": [ [ "species_10784678", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10784137": { "compartment": "compartment_5460", "id": "reaction_10784137", "reactome": "R-SCE-6801328", "name": "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693984", "species_113526" ], "products": [ "species_6801458", "species_29362" ], "modifiers": [ [ "species_10784132", "catalyst" ] ], "additional_components": [ "YBR084W" ] }, "reaction_10763379": { "compartment": "compartment_70101", "id": "reaction_10763379", "reactome": "R-SCE-73810", "name": "FGAM + ATP => AIR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111369" ], "products": [ "species_70106", "species_29370", "species_111370", "species_29372" ], "modifiers": [ [ "species_10763376", "catalyst" ] ], "additional_components": [ "YGL234W" ] }, "reaction_10771277": { "compartment": "compartment_5460", "id": "reaction_10771277", "reactome": "R-SCE-880007", "name": "(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_879997" ], "products": [ "species_113594", "species_31649" ], "modifiers": [ [ "species_10771274", "catalyst" ], [ "species_880069", "catalyst" ], [ "species_113527", "catalyst" ], [ "species_880067", "catalyst" ] ], "additional_components": [ "YDL178W" ] }, "reaction_10766543": { "compartment": "compartment_17927", "id": "reaction_10766543", "reactome": "R-SCE-189423", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189478" ], "products": [ "species_189481", "species_189463" ], "modifiers": [ [ "species_10766540", "catalyst" ] ], "additional_components": [ "P40012", "YER014W", "species_113596" ] }, "reaction_10773316": { "compartment": "compartment_12045", "id": "reaction_10773316", "reactome": "R-SCE-1483190", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_428686" ], "products": [ "species_111294", "species_1500603" ], "modifiers": [ [ "species_10773313", "catalyst" ] ], "additional_components": [ "P33412", "YGR007W" ] }, "reaction_10773052": { "compartment": "compartment_70616", "id": "reaction_10773052", "reactome": "R-SCE-1482689", "name": "1-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524027", "species_1524038" ], "products": [ "species_1524042", "species_29374" ], "modifiers": [ [ "species_10772962", "catalyst" ] ], "additional_components": [ "YDL142C" ] }, "reaction_10768252": { "compartment": "compartment_876", "id": "reaction_10768252", "reactome": "R-SCE-266070", "name": "LTC4 is exported from the cytosol by ABCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266066" ], "products": [ "species_266013" ], "modifiers": [ [ "species_10768249", "catalyst" ] ], "additional_components": [ "YDR135C" ] }, "reaction_10761148": { "compartment": "compartment_70101", "id": "reaction_10761148", "reactome": "R-SCE-70349", "name": "DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_30393" ], "products": [ "species_29370", "species_29578" ], "modifiers": [ [ "species_10761145", "catalyst" ] ], "additional_components": [ "P54838", "YML070W", "species_109496" ] }, "reaction_10766599": { "compartment": "compartment_70101", "id": "reaction_10766599", "reactome": "R-SCE-189488", "name": "UROS transforms HMB to URO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189449" ], "products": [ "species_189407", "species_29356" ], "modifiers": [ [ "species_10766596", "catalyst" ] ], "additional_components": [ "YOR278W" ] }, "reaction_10773148": { "compartment": "compartment_12045", "id": "reaction_10773148", "reactome": "R-SCE-1482861", "name": "MLCL is acylated to CL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524069", "species_1500578" ], "products": [ "species_76194", "species_1524081" ], "modifiers": [ [ "species_10764105", "catalyst" ] ], "additional_components": [ "YBR042C" ] }, "reaction_10784649": { "compartment": "compartment_13977", "id": "reaction_10784649", "reactome": "R-SCE-6808464", "name": "ALDH3B2 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_29356", "species_6808468" ], "products": [ "species_70106", "species_73473", "species_2453691" ], "modifiers": [ [ "species_10784646", "catalyst" ] ], "additional_components": [ "YMR110C" ] }, "reaction_10773056": { "compartment": "compartment_12045", "id": "reaction_10773056", "reactome": "R-SCE-1482696", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10764653": { "compartment": "compartment_70101", "id": "reaction_10764653", "reactome": "R-SCE-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6788778" ], "products": [ "species_29370", "species_6788782" ], "modifiers": [ [ "species_10764648", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "P26364", "YER170W", "P07170", "YDR226W" ] }, "reaction_10787680": { "compartment": "compartment_70101", "id": "reaction_10787680", "reactome": "R-SCE-8954327", "name": "UCKL1 phosphorylates urindine, cytidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500759", "species_113592" ], "products": [ "species_29370", "species_500761" ], "modifiers": [ [ "species_10787677", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:16704", "species_109395", "species_109402", "YNR012W" ] }, "reaction_10762000": { "compartment": "compartment_70101", "id": "reaction_10762000", "reactome": "R-SCE-71552", "name": "limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761969" ], "products": [ "species_10761992" ], "modifiers": [ [ "species_10761997", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_113527", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_113527", "P36143", "YKR058W", "YPR184W" ] }, "reaction_10776278": { "compartment": "compartment_70101", "id": "reaction_10776278", "reactome": "R-SCE-3781024", "name": "GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10776273" ], "products": [ "species_10776259", "species_109402" ], "modifiers": [ [ "species_10776273", "catalyst" ] ], "additional_components": [ "P40187", "YIL045W", "P40036", "YER054C", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P46958", "YJL146W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P40036", "YER054C", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10787833": { "compartment": "compartment_70101", "id": "reaction_10787833", "reactome": "R-SCE-8982667", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787326" ], "products": [ "species_6787328" ], "modifiers": [ [ "species_10761119", "catalyst" ] ], "additional_components": [ "Q03262", "YMR278W", "species_109496" ] }, "reaction_10788340": { "compartment": "compartment_70101", "id": "reaction_10788340", "reactome": "R-SCE-9018862", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9022655" ], "products": [ "species_9022660" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10773563": { "compartment": "compartment_171062", "id": "reaction_10773563", "reactome": "R-SCE-1676105", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806205", "species_29356" ], "products": [ "species_1806259", "species_29372" ], "modifiers": [ [ "species_10773463", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10774859": { "compartment": "compartment_5460", "id": "reaction_10774859", "reactome": "R-SCE-2995334", "name": "COX15 transforms heme O to heme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2995328" ], "products": [ "species_2995348" ], "modifiers": [ [ "species_10774856", "catalyst" ] ], "additional_components": [ "YER141W" ] }, "reaction_10781907": { "compartment": "compartment_5460", "id": "reaction_10781907", "reactome": "R-SCE-6784393", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587", "species_6784236" ], "products": [ "species_6784229", "species_113553" ], "modifiers": [ [ "species_10761497", "catalyst" ] ], "additional_components": [ "Q01802", "YKL106W" ] }, "reaction_10773380": { "compartment": "compartment_70101", "id": "reaction_10773380", "reactome": "R-SCE-1614524", "name": "PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369", "species_200736" ], "products": [ "species_1614518", "species_29356" ], "modifiers": [ [ "species_10773377", "catalyst" ] ], "additional_components": [ "P32582", "YGR155W", "species_189444" ] }, "reaction_10775560": { "compartment": "compartment_70101", "id": "reaction_10775560", "reactome": "R-SCE-3322005", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775513" ], "products": [ "species_10775552" ], "modifiers": [ [ "species_10775557", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "YEL011W" ] }, "reaction_10782009": { "compartment": "compartment_70101", "id": "reaction_10782009", "reactome": "R-SCE-6788295", "name": "HDHD1:Mg2+ dephosphorylates PURIDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788291", "species_29356" ], "products": [ "species_29372", "species_6788290" ], "modifiers": [ [ "species_10782006", "catalyst" ] ], "additional_components": [ "Q86ZR7", "YKL033W-A", "species_109496" ] }, "reaction_10781636": { "compartment": "compartment_12045", "id": "reaction_10781636", "reactome": "R-SCE-5696424", "name": "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696426", "species_192172" ], "products": [ "species_162743", "species_5696412" ], "modifiers": [ [ "species_10781633", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10771046": { "compartment": "compartment_876", "id": "reaction_10771046", "reactome": "R-SCE-499981", "name": "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10771043", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10782630": { "compartment": "compartment_5460", "id": "reaction_10782630", "reactome": "R-SCE-6793591", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6793610", "species_10782620", "species_2162265" ], "products": [ "species_10781283", "species_6793613", "species_379705" ], "modifiers": [ [ "species_10782627", "catalyst" ] ], "additional_components": [ "YAL044C", "YAL044C", "CHEBI:49883", "P32875", "YOR196C" ] }, "reaction_10769056": { "compartment": "compartment_17951", "id": "reaction_10769056", "reactome": "R-SCE-390252", "name": "HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390249", "species_141343" ], "products": [ "species_390248" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10772015": { "compartment": "compartment_70101", "id": "reaction_10772015", "reactome": "R-SCE-977324", "name": "PSPH:Mg2+ dimer dephosphorylates O-P-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_936706" ], "products": [ "species_200736", "species_29372" ], "modifiers": [ [ "species_10772012", "catalyst" ] ], "additional_components": [ "P42941", "YGR208W", "species_109496" ] }, "reaction_10766979": { "compartment": "compartment_70101", "id": "reaction_10766979", "reactome": "R-SCE-196929", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73524", "species_113592" ], "products": [ "species_29386", "species_111294" ], "modifiers": [ [ "species_10766976", "catalyst" ] ], "additional_components": [ "YDL045C" ] }, "reaction_10781999": { "compartment": "compartment_17951", "id": "reaction_10781999", "reactome": "R-SCE-6787811", "name": "HAO2 tetramer oxidises 2OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787810", "species_113535" ], "products": [ "species_6787814", "species_113575" ], "modifiers": [ [ "species_10781996", "catalyst" ] ], "additional_components": [ "P00175", "CYB2" ] }, "reaction_10761476": { "compartment": "compartment_70101", "id": "reaction_10761476", "reactome": "R-SCE-70573", "name": "argininosuccinate <=> fumarate + arginine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_34575" ], "products": [ "species_29586", "species_29468" ], "modifiers": [ [ "species_10761473", "catalyst" ] ], "additional_components": [ "P04076", "YHR018C" ] }, "reaction_10766690": { "compartment": "compartment_70101", "id": "reaction_10766690", "reactome": "R-SCE-191299", "name": "Squalene is oxidized to its epoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191269", "species_29368" ], "products": [ "species_29366", "species_191309", "species_29356" ], "modifiers": [ [ "species_10766687", "catalyst" ] ], "additional_components": [ "P32476", "YGR175C", "species_113596" ] }, "reaction_10761732": { "compartment": "compartment_5460", "id": "reaction_10761732", "reactome": "R-SCE-70997", "name": "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_70958" ], "products": [ "species_29374", "species_113536", "species_113593" ], "modifiers": [ [ "species_10761729", "catalyst" ] ], "additional_components": [ "P53598", "YOR142W", "P53312", "YGR244C" ] }, "reaction_10786830": { "compartment": "compartment_17927", "id": "reaction_10786830", "reactome": "R-SCE-8875838", "name": "SLC25A19 transports ThDP from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29480" ], "products": [ "species_8878387" ], "modifiers": [ [ "species_10786827", "catalyst" ] ], "additional_components": [ "YGR096W" ] }, "reaction_10765677": { "compartment": "compartment_70101", "id": "reaction_10765677", "reactome": "R-SCE-163764", "name": "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29878", "species_29512" ], "products": [ "species_29578", "species_29882" ], "modifiers": [ [ "species_10761886", "catalyst" ] ], "additional_components": [ "P15019", "YLR354C" ] }, "reaction_10767455": { "compartment": "compartment_17927", "id": "reaction_10767455", "reactome": "R-SCE-200424", "name": "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_201023", "species_201034" ], "products": [ "species_549207", "species_201050" ], "modifiers": [ [ "species_10767452", "catalyst" ] ], "additional_components": [ "YOR100C" ] }, "reaction_10763358": { "compartment": "compartment_70101", "id": "reaction_10763358", "reactome": "R-SCE-73797", "name": "FAICAR => IMP + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111427" ], "products": [ "species_29602", "species_29356" ], "modifiers": [ [ "species_10763355", "catalyst" ] ], "additional_components": [ "P38009", "YMR120C" ] }, "reaction_10773353": { "compartment": "compartment_70101", "id": "reaction_10773353", "reactome": "R-SCE-1497810", "name": "Uncoupled eNOS favours the formation of superoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29368" ], "products": [ "species_29366", "species_1222424" ], "modifiers": [ [ "species_10773348", "catalyst" ] ], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "species_1497857", "species_29870", "P15108", "YMR186W", "species_113596", "P11792", "YHR205W" ] }, "reaction_10788219": { "compartment": "compartment_70101", "id": "reaction_10788219", "reactome": "R-SCE-9014741", "name": "PXLP-K56-SRR dimer deaminates D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_376186" ], "products": [ "species_29382", "species_29398", "species_29356" ], "modifiers": [ [ "species_10788216", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "P36007", "YKL218C" ] }, "reaction_10786160": { "compartment": "compartment_12045", "id": "reaction_10786160", "reactome": "R-SCE-8857686", "name": "FITM1, FITM2 bind TAGs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786156", "species_549167" ], "products": [ "species_10786158" ], "modifiers": [], "additional_components": [ "Q06676", "YDR319C", "P53012", "YGL126W", "species_549167", "Q06676", "YDR319C", "P53012", "YGL126W" ] }, "reaction_10767260": { "compartment": "compartment_876", "id": "reaction_10767260", "reactome": "R-SCE-198818", "name": "SLC2A1,3 transports DeHA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198852" ], "products": [ "species_198827" ], "modifiers": [ [ "species_10767257", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10762137": { "compartment": "compartment_5460", "id": "reaction_10762137", "reactome": "R-SCE-71723", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_113532" ], "products": [ "species_113539", "species_29362", "species_113529" ], "modifiers": [ [ "species_10762134", "catalyst" ] ], "additional_components": [ "P40047", "YER073W" ] }, "reaction_10763070": { "compartment": "compartment_70101", "id": "reaction_10763070", "reactome": "R-SCE-73571", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_111628" ], "products": [ "species_29356", "species_76630" ], "modifiers": [ [ "species_10763067", "catalyst" ] ], "additional_components": [ "P07259", "YJL130C", "P03965", "YJR109C" ] }, "reaction_10769862": { "compartment": "compartment_70101", "id": "reaction_10769862", "reactome": "R-SCE-428273", "name": "SPHK1 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_29370", "species_428203" ], "modifiers": [ [ "species_10769088", "catalyst" ] ], "additional_components": [ "YLR260W" ] }, "reaction_10785507": { "compartment": "compartment_876", "id": "reaction_10785507", "reactome": "R-SCE-8850854", "name": "NTPDase1 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8870906", "species_109276" ], "products": [ "species_8870962", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785501", "catalyst" ] ], "additional_components": [ "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10788350": { "compartment": "compartment_70101", "id": "reaction_10788350", "reactome": "R-SCE-9020258", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024768" ], "products": [ "species_9024759" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "CHEBI:81565", "CHEBI:81564", "species_158417", "Q10740", "YNL045W" ] }, "reaction_10784145": { "compartment": "compartment_70101", "id": "reaction_10784145", "reactome": "R-SCE-6801342", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803257", "species_113592" ], "products": [ "species_70106", "species_29370", "species_200640", "species_29372" ], "modifiers": [ [ "species_10784142", "catalyst" ] ], "additional_components": [ "YER183C" ] }, "reaction_10777793": { "compartment": "compartment_984", "id": "reaction_10777793", "reactome": "R-SCE-5433072", "name": "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490253", "species_109276" ], "products": [ "species_210382", "species_5490235" ], "modifiers": [ [ "species_10777790", "catalyst" ] ], "additional_components": [ "CHEBI:78587", "CHEBI:78581", "CHEBI:78579", "CHEBI:78584", "Q05902", "YLR299W" ] }, "reaction_10784767": { "compartment": "compartment_70101", "id": "reaction_10784767", "reactome": "R-SCE-6809764", "name": "SBF1 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784763", "species_10773465" ], "products": [ "species_10784765" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10773553": { "compartment": "compartment_876", "id": "reaction_10773553", "reactome": "R-SCE-1675994", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10773550", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "P47147", "YJR110W", "P50942", "YNL106C" ] }, "reaction_10771041": { "compartment": "compartment_5460", "id": "reaction_10771041", "reactome": "R-SCE-482812", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_482807", "species_113581" ], "products": [ "species_482803", "species_113593" ], "modifiers": [ [ "species_10771036", "catalyst" ] ], "additional_components": [ "species_29494", "species_500739", "species_29892", "species_110644", "species_30185", "species_30187", "species_29438", "species_110614", "species_29420", "CHEBI:60471", "CHEBI:58369", "CHEBI:58595", "CHEBI:57667", "species_110096", "species_110094", "CHEBI:58593", "P36010", "YKL067W" ] }, "reaction_10767033": { "compartment": "compartment_70101", "id": "reaction_10767033", "reactome": "R-SCE-197235", "name": "NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_197220" ], "products": [ "species_197256", "species_111294" ], "modifiers": [ [ "species_10767030", "catalyst" ] ], "additional_components": [ "Q06178", "YLR328W", "P53204", "YGR010W", "species_109496" ] }, "reaction_10765667": { "compartment": "compartment_7660", "id": "reaction_10765667", "reactome": "R-SCE-163664", "name": "AMP binds to gamma subunit of AMP kinase heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765661", "species_164121" ], "products": [ "species_10765665" ], "modifiers": [], "additional_components": [ "P34164", "YGL208W", "Q04739", "YER027C", "P32578", "YDR422C", "P12904", "YGL115W", "P38845", "YHR146W", "P06782", "YDR477W", "P53885", "YNL173C", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P32578", "YDR422C", "P12904", "YGL115W", "P38845", "YHR146W", "P06782", "YDR477W", "P53885", "YNL173C" ] }, "reaction_10787120": { "compartment": "compartment_70101", "id": "reaction_10787120", "reactome": "R-SCE-8932980", "name": "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_8932979" ], "modifiers": [ [ "species_10787109", "catalyst" ] ], "additional_components": [ "YDR105C" ] }, "reaction_10764159": { "compartment": "compartment_70101", "id": "reaction_10764159", "reactome": "R-SCE-75899", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76108" ], "products": [ "species_76103", "species_29372" ], "modifiers": [ [ "species_10764152", "catalyst" ] ], "additional_components": [ "YMR165C" ] }, "reaction_10769052": { "compartment": "compartment_17951", "id": "reaction_10769052", "reactome": "R-SCE-390250", "name": "3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193514", "species_390241" ], "products": [ "species_353123", "species_390246" ], "modifiers": [ [ "species_10769049", "catalyst" ] ], "additional_components": [ "YIL160C" ] }, "reaction_10773616": { "compartment": "compartment_20699", "id": "reaction_10773616", "reactome": "R-SCE-1676204", "name": "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806230", "species_29356" ], "products": [ "species_1806217", "species_29372" ], "modifiers": [ [ "species_10773611", "catalyst" ] ], "additional_components": [ "YNL128W" ] }, "reaction_10767527": { "compartment": "compartment_70101", "id": "reaction_10767527", "reactome": "R-SCE-200711", "name": "MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29460", "species_197969" ], "products": [ "species_29370", "species_111353", "species_29372" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10771991": { "compartment": "compartment_70101", "id": "reaction_10771991", "reactome": "R-SCE-964962", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965053", "species_113592" ], "products": [ "species_29370", "species_964952" ], "modifiers": [ [ "species_10771986", "catalyst" ] ], "additional_components": [ "species_158417", "P39988", "YEL029C" ] }, "reaction_10773140": { "compartment": "compartment_70616", "id": "reaction_10773140", "reactome": "R-SCE-1482850", "name": "MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498773", "species_1524083" ], "products": [ "species_1524072", "species_1524089" ], "modifiers": [ [ "species_10773113", "catalyst" ] ], "additional_components": [] }, "reaction_10773208": { "compartment": "compartment_12045", "id": "reaction_10773208", "reactome": "R-SCE-1482962", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500603", "species_1500596" ], "products": [ "species_109395", "species_1500581" ], "modifiers": [ [ "species_10773205", "catalyst" ] ], "additional_components": [ "P17898", "YNL130C", "P22140", "YHR123W", "species_113527", "species_109496" ] }, "reaction_10784770": { "compartment": "compartment_70101", "id": "reaction_10784770", "reactome": "R-SCE-6809777", "name": "PI3P is dephosphorylated to PI by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030", "species_29356" ], "products": [ "species_426639", "species_29372" ], "modifiers": [ [ "species_10784765", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10788208": { "compartment": "compartment_70101", "id": "reaction_10788208", "reactome": "R-SCE-9014627", "name": "SDS dimers:PXLP dehydrate L-Thr to 2AA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351990" ], "products": [ "species_9014643", "species_29356" ], "modifiers": [ [ "species_10788205", "catalyst" ] ], "additional_components": [ "P25379", "YCL064C" ] }, "reaction_10769066": { "compartment": "compartment_17951", "id": "reaction_10769066", "reactome": "R-SCE-390304", "name": "acetyl-CoA + H2O => acetate + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353123", "species_141343" ], "products": [ "species_193514", "species_390305" ], "modifiers": [ [ "species_10766854", "catalyst" ] ], "additional_components": [ "YJR019C" ] }, "reaction_10766152": { "compartment": "compartment_5460", "id": "reaction_10766152", "reactome": "R-SCE-169260", "name": "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766147", "species_31649" ], "products": [ "species_10766149", "species_113596" ], "modifiers": [ [ "species_10766147", "catalyst" ] ], "additional_components": [ "species_76577", "Q12480", "YPR004C", "P42940", "YGR207C", "species_113596", "species_76577", "species_31649", "Q12480", "YPR004C", "P42940", "YGR207C", "species_76577", "Q12480", "YPR004C", "P42940", "YGR207C", "species_113596" ] }, "reaction_10773039": { "compartment": "compartment_12045", "id": "reaction_10773039", "reactome": "R-SCE-1482636", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498724", "species_1500578" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10772920", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10772026": { "compartment": "compartment_70101", "id": "reaction_10772026", "reactome": "R-SCE-977333", "name": "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_977329" ], "products": [ "species_936706", "species_29406" ], "modifiers": [ [ "species_10772023", "catalyst" ] ], "additional_components": [ "P33330", "YOR184W" ] }, "reaction_10766425": { "compartment": "compartment_70101", "id": "reaction_10766425", "reactome": "R-SCE-177784", "name": "ribose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10761876", "catalyst" ] ], "additional_components": [ "YOR095C" ] }, "reaction_10762017": { "compartment": "compartment_70101", "id": "reaction_10762017", "reactome": "R-SCE-71590", "name": "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762014", "species_29372" ], "products": [ "species_10761967", "species_29548" ], "modifiers": [ [ "species_10762009", "catalyst" ] ], "additional_components": [ "P47011", "YJL137C", "species_113527", "P47011", "YJL137C", "species_113527", "P06738", "YPR160W" ] }, "reaction_10773054": { "compartment": "compartment_12045", "id": "reaction_10773054", "reactome": "R-SCE-1482691", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498722", "species_1500578" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10772920", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10774286": { "compartment": "compartment_70101", "id": "reaction_10774286", "reactome": "R-SCE-2393939", "name": "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1131972" ], "products": [ "species_73578", "species_76577" ], "modifiers": [ [ "species_10774283", "catalyst" ] ], "additional_components": [ "Q01976", "YBR111C", "species_109496" ] }, "reaction_10769044": { "compartment": "compartment_17951", "id": "reaction_10769044", "reactome": "R-SCE-389995", "name": "3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192307", "species_389982" ], "products": [ "species_389996", "species_193465", "species_192305" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10763073": { "compartment": "compartment_70101", "id": "reaction_10763073", "reactome": "R-SCE-73573", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29448", "species_111647" ], "products": [ "species_70106", "species_29372", "species_111628" ], "modifiers": [ [ "species_10763067", "catalyst" ] ], "additional_components": [ "P07259", "YJL130C", "P03965", "YJR109C" ] }, "reaction_10782024": { "compartment": "compartment_5460", "id": "reaction_10782024", "reactome": "R-SCE-6788798", "name": "AK4 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788802", "species_113593" ], "products": [ "species_113581", "species_6788801" ], "modifiers": [ [ "species_10782021", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "YER170W" ] }, "reaction_10773472": { "compartment": "compartment_172574", "id": "reaction_10773472", "reactome": "R-SCE-1675795", "name": "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806198", "species_29356" ], "products": [ "species_1806195", "species_29372" ], "modifiers": [ [ "species_10773463", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10769935": { "compartment": "compartment_70101", "id": "reaction_10769935", "reactome": "R-SCE-428701", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10769886", "catalyst" ] ], "additional_components": [ "P47013", "YJL134W", "P23501", "YKR053C" ] }, "reaction_10768244": { "compartment": "compartment_876", "id": "reaction_10768244", "reactome": "R-SCE-266046", "name": "GGT1, 5 dimers hydrolyse LTC4 to LTD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266013", "species_109276" ], "products": [ "species_210382", "species_266074" ], "modifiers": [ [ "species_10768241", "catalyst" ] ], "additional_components": [ "Q05902", "YLR299W" ] }, "reaction_10776221": { "compartment": "compartment_70101", "id": "reaction_10776221", "reactome": "R-SCE-3780994", "name": "GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10776213" ], "products": [ "species_10776218", "species_109402" ], "modifiers": [ [ "species_10776213", "catalyst" ] ], "additional_components": [ "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10771993": { "compartment": "compartment_70101", "id": "reaction_10771993", "reactome": "R-SCE-964970", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965131", "species_113592" ], "products": [ "species_29370", "species_29390" ], "modifiers": [ [ "species_10771986", "catalyst" ] ], "additional_components": [ "species_158417", "P39988", "YEL029C" ] }, "reaction_10773571": { "compartment": "compartment_20699", "id": "reaction_10773571", "reactome": "R-SCE-1676114", "name": "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806159", "species_29356" ], "products": [ "species_1524146", "species_29372" ], "modifiers": [ [ "species_10773568", "catalyst" ] ], "additional_components": [ "YKL212W" ] }, "reaction_10767728": { "compartment": "compartment_70101", "id": "reaction_10767728", "reactome": "R-SCE-203611", "name": "N-myristoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_184174", "species_10767726" ], "products": [ "species_10767644" ], "modifiers": [], "additional_components": [ "YHR042W", "YHR042W" ] }, "reaction_10773396": { "compartment": "compartment_70101", "id": "reaction_10773396", "reactome": "R-SCE-1614583", "name": "PXLP-K212-CTH cleaves L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614518", "species_29356" ], "products": [ "species_29382", "species_936714", "species_111707" ], "modifiers": [ [ "species_10773390", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10761549": { "compartment": "compartment_70101", "id": "reaction_10761549", "reactome": "R-SCE-70634", "name": "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498", "species_113567" ], "products": [ "species_113585", "species_29968" ], "modifiers": [ [ "species_10761546", "catalyst" ] ], "additional_components": [ "Q12375", "YOR130C", "P38087", "YBR104W", "P32331", "YPR058W" ] }, "reaction_10766880": { "compartment": "compartment_876", "id": "reaction_10766880", "reactome": "R-SCE-194153", "name": "ABCC3 transports bile salts from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_194156" ], "products": [ "species_29370", "species_192483", "species_29372" ], "modifiers": [ [ "species_10766877", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "CHEBI:16755", "species_193451", "CHEBI:16525", "CHEBI:28865", "CHEBI:36274", "CHEBI:17687", "CHEBI:16755", "species_193451", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274", "YGR281W" ] }, "reaction_10764658": { "compartment": "compartment_70101", "id": "reaction_10764658", "reactome": "R-SCE-110144", "name": "ADP + ADP <=> AMP + ATP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370" ], "products": [ "species_113592", "species_76577" ], "modifiers": [ [ "species_10764655", "catalyst" ] ], "additional_components": [ "YDR226W" ] }, "reaction_10785452": { "compartment": "compartment_12045", "id": "reaction_10785452", "reactome": "R-SCE-8848582", "name": "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848577", "species_200993" ], "products": [ "species_76194", "species_8848499" ], "modifiers": [ [ "species_10781638", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10766928": { "compartment": "compartment_70101", "id": "reaction_10766928", "reactome": "R-SCE-196350", "name": "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_29360" ], "products": [ "species_70106", "species_73473", "species_196344" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10761446": { "compartment": "compartment_5460", "id": "reaction_10761446", "reactome": "R-SCE-70555", "name": "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113561", "species_29896", "species_113593" ], "products": [ "species_29676", "species_113548", "species_113581" ], "modifiers": [ [ "species_10761443", "catalyst" ], [ "species_30471", "catalyst" ] ], "additional_components": [ "YJL130C" ] }, "reaction_10764500": { "compartment": "compartment_70101", "id": "reaction_10764500", "reactome": "R-SCE-109624", "name": "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500173", "species_113592" ], "products": [ "species_29370", "species_500088" ], "modifiers": [ [ "species_10764497", "catalyst" ] ], "additional_components": [ "species_83909", "CHEBI:17256", "species_76577", "species_109386", "P47143", "YJR105W", "species_109496" ] }, "reaction_10781620": { "compartment": "compartment_876", "id": "reaction_10781620", "reactome": "R-SCE-5696080", "name": "ALDH3B1 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_29356", "species_428663" ], "products": [ "species_70106", "species_73473", "species_3632881" ], "modifiers": [ [ "species_10781617", "catalyst" ] ], "additional_components": [ "YMR110C" ] }, "reaction_10773589": { "compartment": "compartment_876", "id": "reaction_10773589", "reactome": "R-SCE-1676145", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10773586", "catalyst" ] ], "additional_components": [ "P38994", "YDR208W" ] }, "reaction_10761466": { "compartment": "compartment_70101", "id": "reaction_10761466", "reactome": "R-SCE-70569", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29356" ], "products": [ "species_29498", "species_29514" ], "modifiers": [ [ "species_10761463", "catalyst" ] ], "additional_components": [ "P00812", "YPL111W", "species_113527" ] }, "reaction_10785455": { "compartment": "compartment_12045", "id": "reaction_10785455", "reactome": "R-SCE-8848585", "name": "AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30209", "species_200993" ], "products": [ "species_76194", "species_2534407" ], "modifiers": [ [ "species_10781638", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10766738": { "compartment": "compartment_70101", "id": "reaction_10766738", "reactome": "R-SCE-191380", "name": "Mevalonate is phosphorylated to mevalonate-5-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191424" ], "products": [ "species_29370", "species_191296" ], "modifiers": [ [ "species_10766735", "catalyst" ] ], "additional_components": [ "P07277", "YMR208W" ] }, "reaction_10772862": { "compartment": "compartment_5460", "id": "reaction_10772862", "reactome": "R-SCE-1362408", "name": "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772851", "species_10772838", "species_379721" ], "products": [ "species_10772853", "species_10772859", "species_379697" ], "modifiers": [ [ "species_10772838", "catalyst" ], [ "species_10772851", "catalyst" ] ], "additional_components": [ "CHEBI:33738", "Q12184", "YPL252C", "P25374", "YCL017C", "Q6Q560", "YER048W-A", "species_111793", "Q07540", "YFH1", "Q03020", "YPL135W", "P25374", "YCL017C", "Q6Q560", "YER048W-A", "CHEBI:33739", "Q07540", "YFH1", "Q03020", "YPL135W", "CHEBI:33737", "Q12184", "YPL252C", "P25374", "YCL017C", "Q6Q560", "YER048W-A", "species_111793", "Q07540", "YFH1", "Q03020", "YPL135W", "CHEBI:33738", "Q12184", "YPL252C" ] }, "reaction_10766930": { "compartment": "compartment_70101", "id": "reaction_10766930", "reactome": "R-SCE-196372", "name": "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193124", "species_29360" ], "products": [ "species_70106", "species_73473", "species_196366" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10774126": { "compartment": "compartment_17951", "id": "reaction_10774126", "reactome": "R-SCE-2066788", "name": "Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2066762", "species_193514" ], "products": [ "species_353123", "species_2066765" ], "modifiers": [ [ "species_10769049", "catalyst" ] ], "additional_components": [ "YIL160C" ] }, "reaction_10761825": { "compartment": "compartment_70101", "id": "reaction_10761825", "reactome": "R-SCE-71261", "name": "BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31369", "species_29368", "species_29406" ], "products": [ "species_113528", "species_30235", "species_29434" ], "modifiers": [ [ "species_10761822", "catalyst" ] ], "additional_components": [ "species_111793", "species_198816", "P23180", "YHL021C" ] }, "reaction_10761669": { "compartment": "compartment_5460", "id": "reaction_10761669", "reactome": "R-SCE-70975", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113587", "species_113559" ], "products": [ "species_29374", "species_29654" ], "modifiers": [ [ "species_10761666", "catalyst" ] ], "additional_components": [ "P00890", "CIT1" ] }, "reaction_10788352": { "compartment": "compartment_70101", "id": "reaction_10788352", "reactome": "R-SCE-9020270", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024577" ], "products": [ "species_9024570" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "CHEBI:138616", "CHEBI:138615", "species_158417", "Q10740", "YNL045W" ] }, "reaction_10764963": { "compartment": "compartment_70101", "id": "reaction_10764963", "reactome": "R-SCE-112034", "name": "PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500244", "species_83956" ], "products": [ "species_500245", "species_29372" ], "modifiers": [ [ "species_10763557", "catalyst" ] ], "additional_components": [ "species_112016", "CHEBI:58576", "CHEBI:17172", "CHEBI:16750", "Q05788", "YLR209C" ] }, "reaction_10778389": { "compartment": "compartment_17963", "id": "reaction_10778389", "reactome": "R-SCE-5653873", "name": "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70113" ], "products": [ "species_964746" ], "modifiers": [ [ "species_10778386", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10773283": { "compartment": "compartment_12045", "id": "reaction_10773283", "reactome": "R-SCE-1483121", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_426755" ], "products": [ "species_426955", "species_111294" ], "modifiers": [ [ "species_10773280", "catalyst" ] ], "additional_components": [ "P38221", "YBR029C", "species_109496" ] }, "reaction_10786171": { "compartment": "compartment_70101", "id": "reaction_10786171", "reactome": "R-SCE-8862380", "name": "HSD17B13 binds lipid droplets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866926", "species_10781197" ], "products": [ "species_10786169" ], "modifiers": [], "additional_components": [ "species_163579", "CHEBI:16247", "species_549167", "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C", "species_163579", "CHEBI:16247", "species_549167", "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C" ] }, "reaction_10766710": { "compartment": "compartment_70101", "id": "reaction_10766710", "reactome": "R-SCE-191323", "name": "HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191293", "species_29356", "species_76183" ], "products": [ "species_70106", "species_76194", "species_191374" ], "modifiers": [ [ "species_10766707", "catalyst" ] ], "additional_components": [ "YML126C" ] }, "reaction_10761158": { "compartment": "compartment_70101", "id": "reaction_10761158", "reactome": "R-SCE-70369", "name": "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29452" ], "products": [ "species_29410" ], "modifiers": [ [ "species_10761155", "catalyst" ] ], "additional_components": [ "P04397", "YBR019C", "species_113526" ] }, "reaction_10773537": { "compartment": "compartment_20699", "id": "reaction_10773537", "reactome": "R-SCE-1675961", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806159" ], "modifiers": [ [ "species_10773532", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "species_113527" ] }, "reaction_10781258": { "compartment": "compartment_12045", "id": "reaction_10781258", "reactome": "R-SCE-5693761", "name": "FA2H hydroxylates CERA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_428256" ], "products": [ "species_5693768", "species_29356" ], "modifiers": [ [ "species_10781255", "catalyst" ] ], "additional_components": [ "YMR272C" ] }, "reaction_10786994": { "compartment": "compartment_984", "id": "reaction_10786994", "reactome": "R-SCE-8878787", "name": "ALPI dimer hydrolyses phosphate monoesters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8878780", "species_109276" ], "products": [ "species_109277", "species_8878776" ], "modifiers": [ [ "species_10786991", "catalyst" ] ], "additional_components": [ "species_158417", "P11491", "YDR481C", "species_74016" ] }, "reaction_10785449": { "compartment": "compartment_12045", "id": "reaction_10785449", "reactome": "R-SCE-8848580", "name": "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_76194", "species_1500594" ], "modifiers": [ [ "species_10785444", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10784665": { "compartment": "compartment_5460", "id": "reaction_10784665", "reactome": "R-SCE-6808487", "name": "ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6808499", "species_113563", "species_113521" ], "products": [ "species_113600", "species_200679", "species_29376", "species_113529" ], "modifiers": [ [ "species_10784662", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10764630": { "compartment": "compartment_70101", "id": "reaction_10764630", "reactome": "R-SCE-109903", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500759", "species_113592" ], "products": [ "species_29370", "species_500761" ], "modifiers": [ [ "species_10764627", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:16704", "species_109395", "species_109402", "Q12084", "YDR020C" ] }, "reaction_10773579": { "compartment": "compartment_20699", "id": "reaction_10773579", "reactome": "R-SCE-1676133", "name": "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806217" ], "products": [ "species_1524146", "species_29372" ], "modifiers": [ [ "species_10773568", "catalyst" ] ], "additional_components": [ "YKL212W" ] }, "reaction_10761634": { "compartment": "compartment_5460", "id": "reaction_10761634", "reactome": "R-SCE-70938", "name": "lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113600", "species_29444", "species_113529" ], "products": [ "species_113563", "species_113521", "species_30176" ], "modifiers": [ [ "species_10761631", "catalyst" ] ], "additional_components": [ "P38999", "YNR050C" ] }, "reaction_10761228": { "compartment": "compartment_70101", "id": "reaction_10761228", "reactome": "R-SCE-70420", "name": "HK1,2,3,GCK phosphorylate Glc to form G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_70113" ], "products": [ "species_70106", "species_29370", "species_30537" ], "modifiers": [ [ "species_10761225", "catalyst" ] ], "additional_components": [ "Q04409", "YDR516C", "Q06204", "YLR446W", "P04806", "YFR053C", "P17709", "YCL040W", "P04807", "YGL253W" ] }, "reaction_10788344": { "compartment": "compartment_70101", "id": "reaction_10788344", "reactome": "R-SCE-9020252", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024602", "species_29356" ], "products": [ "species_9024574" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "CHEBI:138179", "CHEBI:138614", "species_158417", "Q10740", "YNL045W" ] }, "reaction_10766553": { "compartment": "compartment_70101", "id": "reaction_10766553", "reactome": "R-SCE-189425", "name": "UROD decarboxylates URO3 to COPRO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189407" ], "products": [ "species_113528", "species_189455" ], "modifiers": [ [ "species_10766550", "catalyst" ] ], "additional_components": [ "P32347", "YDR047W" ] }, "reaction_10766603": { "compartment": "compartment_70101", "id": "reaction_10766603", "reactome": "R-SCE-190141", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766560", "species_190173" ], "products": [ "species_29426", "species_10766601" ], "modifiers": [], "additional_components": [ "species_158417", "P05373", "YGL040C", "species_158417", "species_190173", "P05373", "YGL040C" ] }, "reaction_10761871": { "compartment": "compartment_70101", "id": "reaction_10761871", "reactome": "R-SCE-71303", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29732" ], "products": [ "species_29790" ], "modifiers": [ [ "species_10761868", "catalyst" ] ], "additional_components": [ "P46969", "YJL121C", "species_111793" ] }, "reaction_10766563": { "compartment": "compartment_70101", "id": "reaction_10766563", "reactome": "R-SCE-189439", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189489" ], "products": [ "species_70106", "species_189464", "species_29356" ], "modifiers": [ [ "species_10766560", "catalyst" ] ], "additional_components": [ "species_158417", "P05373", "YGL040C" ] }, "reaction_10766915": { "compartment": "compartment_70101", "id": "reaction_10766915", "reactome": "R-SCE-194718", "name": "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_194657" ], "products": [ "species_73473", "species_70106", "species_194661", "species_113528" ], "modifiers": [ [ "species_10766887", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10774123": { "compartment": "compartment_17951", "id": "reaction_10774123", "reactome": "R-SCE-2066780", "name": "Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2066766" ], "products": [ "species_2066762" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10784308": { "compartment": "compartment_70101", "id": "reaction_10784308", "reactome": "R-SCE-6806877", "name": "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8866401" ], "products": [ "species_29370", "species_6806881" ], "modifiers": [ [ "species_10784305", "catalyst" ] ], "additional_components": [ "P36010", "YKL067W" ] }, "reaction_10784740": { "compartment": "compartment_70101", "id": "reaction_10784740", "reactome": "R-SCE-6809309", "name": "MTMR6 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773548", "species_10784724" ], "products": [ "species_10784738" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10763122": { "compartment": "compartment_70101", "id": "reaction_10763122", "reactome": "R-SCE-73596", "name": "dCMP + H2O => dUMP + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_109378", "species_29356" ], "products": [ "species_109382", "species_31633" ], "modifiers": [ [ "species_10763119", "catalyst" ] ], "additional_components": [ "P06773", "YHR144C" ] }, "reaction_10769900": { "compartment": "compartment_70101", "id": "reaction_10769900", "reactome": "R-SCE-428681", "name": "sphinganine 1-phosphate => phosphoethanolamine + hexadecanal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428275" ], "products": [ "species_428686", "species_428663" ], "modifiers": [ [ "species_10769895", "catalyst" ] ], "additional_components": [ "YDR294C" ] }, "reaction_10770866": { "compartment": "compartment_5460", "id": "reaction_10770866", "reactome": "R-SCE-450975", "name": "isocitrate <=> citrate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29938" ], "products": [ "species_29654" ], "modifiers": [ [ "species_10761657", "catalyst" ] ], "additional_components": [] }, "reaction_10766533": { "compartment": "compartment_17927", "id": "reaction_10766533", "reactome": "R-SCE-189421", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189411", "species_189461" ], "products": [ "species_189481", "species_189480", "species_189478" ], "modifiers": [ [ "species_10766530", "catalyst" ] ], "additional_components": [ "P11353", "YDR044W" ] }, "reaction_10763393": { "compartment": "compartment_70101", "id": "reaction_10763393", "reactome": "R-SCE-73814", "name": "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_113592", "species_111292" ], "products": [ "species_70106", "species_29370", "species_111338", "species_29372" ], "modifiers": [ [ "species_10763376", "catalyst" ] ], "additional_components": [ "YGL234W" ] }, "reaction_10771060": { "compartment": "compartment_70101", "id": "reaction_10771060", "reactome": "R-SCE-504054", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29494", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_110614", "species_29372" ], "modifiers": [ [ "species_10771057", "catalyst" ] ], "additional_components": [ "P28274", "YBL039C", "P38627", "YJR103W" ] }, "reaction_10784318": { "compartment": "compartment_5460", "id": "reaction_10784318", "reactome": "R-SCE-6806966", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807473" ], "products": [ "species_6807477" ], "modifiers": [ [ "species_10784315", "catalyst" ] ], "additional_components": [ "P40165", "YNL200C" ] }, "reaction_10778609": { "compartment": "compartment_70101", "id": "reaction_10778609", "reactome": "R-SCE-5662471", "name": "SORD tetramer oxidizes xylitol to D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5660033", "species_29360" ], "products": [ "species_70106", "species_73473", "species_5661281" ], "modifiers": [ [ "species_10778317", "catalyst" ] ], "additional_components": [ "Q07993", "YLR070C", "species_158417", "Q07786", "YDL246C", "P35497", "YJR159W" ] }, "reaction_10773555": { "compartment": "compartment_172574", "id": "reaction_10773555", "reactome": "R-SCE-1676024", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806195" ], "products": [ "species_29370", "species_1806198" ], "modifiers": [ [ "species_10773532", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "species_113527" ] }, "reaction_10773582": { "compartment": "compartment_876", "id": "reaction_10773582", "reactome": "R-SCE-1676134", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_1806224" ], "modifiers": [ [ "species_10773418", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10775627": { "compartment": "compartment_70101", "id": "reaction_10775627", "reactome": "R-SCE-3323111", "name": "Cytoslic carboxylases translocate to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774825" ], "products": [ "species_10774951" ], "modifiers": [], "additional_components": [ "P11154", "YGL062W", "species_113527", "P11154", "YGL062W", "species_113527" ] }, "reaction_10772944": { "compartment": "compartment_12045", "id": "reaction_10772944", "reactome": "R-SCE-1482543", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_29356" ], "products": [ "species_76116", "species_1500593" ], "modifiers": [ [ "species_10772941", "catalyst" ] ], "additional_components": [ "P28321", "YKL094W" ] }, "reaction_10766885": { "compartment": "compartment_70101", "id": "reaction_10766885", "reactome": "R-SCE-194641", "name": "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194644", "species_29368" ], "products": [ "species_29366", "species_194735", "species_29356" ], "modifiers": [ [ "species_10766882", "catalyst" ] ], "additional_components": [ "YGR060W" ] }, "reaction_10766847": { "compartment": "compartment_70101", "id": "reaction_10766847", "reactome": "R-SCE-193052", "name": "Pregn-5-ene-3,20-dione isomerizes to progesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196344" ], "products": [ "species_193055" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10761580": { "compartment": "compartment_5460", "id": "reaction_10761580", "reactome": "R-SCE-70670", "name": "PRODH oxidises L-Pro to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_379717", "species_113597" ], "products": [ "species_164934", "species_113529", "species_113590" ], "modifiers": [ [ "species_10761577", "catalyst" ] ], "additional_components": [ "YLR142W" ] }, "reaction_10768933": { "compartment": "compartment_17951", "id": "reaction_10768933", "reactome": "R-SCE-389611", "name": "2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389594" ], "products": [ "species_389578", "species_389636" ], "modifiers": [ [ "species_10768930", "catalyst" ] ], "additional_components": [ "species_29480", "species_109496", "P39994", "YEL020C" ] }, "reaction_10772867": { "compartment": "compartment_5460", "id": "reaction_10772867", "reactome": "R-SCE-1362416", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772865", "species_113531" ], "products": [ "species_10772838" ], "modifiers": [], "additional_components": [ "P25374", "YCL017C", "Q6Q560", "YER048W-A", "Q07540", "YFH1", "Q03020", "YPL135W", "P25374", "YCL017C", "Q6Q560", "YER048W-A", "species_111793", "Q07540", "YFH1", "Q03020", "YPL135W" ] }, "reaction_10767499": { "compartment": "compartment_70101", "id": "reaction_10767499", "reactome": "R-SCE-200661", "name": "MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111353" ], "products": [ "species_200640", "species_29356" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10774100": { "compartment": "compartment_12045", "id": "reaction_10774100", "reactome": "R-SCE-2046093", "name": "Translocation of tetracosapentaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046050", "species_211579" ], "products": [ "species_2046055", "species_5228339", "species_211606" ], "modifiers": [ [ "species_10768821", "catalyst" ] ], "additional_components": [ "YPL147W" ] }, "reaction_10787692": { "compartment": "compartment_70101", "id": "reaction_10787692", "reactome": "R-SCE-8955760", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800", "species_30537" ], "products": [ "species_70106", "species_29728", "species_8955759" ], "modifiers": [ [ "species_10761123", "catalyst" ] ], "additional_components": [ "Q03262", "YMR278W", "species_109496" ] }, "reaction_10784147": { "compartment": "compartment_5460", "id": "reaction_10784147", "reactome": "R-SCE-6801456", "name": "MTHFD1L transforms 10-formyl-THF to HCOOH and THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5389850", "species_113548", "species_113581" ], "products": [ "species_200671", "species_6801451", "species_113593" ], "modifiers": [ [ "species_10781645", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10770911": { "compartment": "compartment_5460", "id": "reaction_10770911", "reactome": "R-SCE-452036", "name": "arginine + H2O => ornithine + urea [ARG2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_374064" ], "products": [ "species_113585", "species_374061" ], "modifiers": [ [ "species_10770908", "catalyst" ] ], "additional_components": [ "P00812", "YPL111W", "species_113527" ] }, "reaction_10766849": { "compartment": "compartment_70101", "id": "reaction_10766849", "reactome": "R-SCE-193073", "name": "HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_176626" ], "products": [ "species_70106", "species_73473", "species_193079" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10769061": { "compartment": "compartment_17951", "id": "reaction_10769061", "reactome": "R-SCE-390284", "name": "propionyl-CoA + carnitine => propionylcarnitine + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390294", "species_192314" ], "products": [ "species_193514", "species_390274" ], "modifiers": [ [ "species_10769058", "catalyst" ] ], "additional_components": [ "YML042W" ] }, "reaction_10763317": { "compartment": "compartment_70101", "id": "reaction_10763317", "reactome": "R-SCE-73792", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111584", "species_29472", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29404", "species_111294", "species_76577", "species_113578" ], "modifiers": [ [ "species_10763314", "catalyst" ] ], "additional_components": [ "YMR217W" ] }, "reaction_10781076": { "compartment": "compartment_70101", "id": "reaction_10781076", "reactome": "R-SCE-5692237", "name": "ADH5 oxidises S-HMGSH to S-FGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5692221", "species_29360" ], "products": [ "species_73473", "species_70106", "species_5692249" ], "modifiers": [ [ "species_10781073", "catalyst" ] ], "additional_components": [ "species_158417", "P32771", "YDL168W" ] }, "reaction_10767529": { "compartment": "compartment_70101", "id": "reaction_10767529", "reactome": "R-SCE-200718", "name": "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200640" ], "products": [ "species_29366", "species_200739" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10774098": { "compartment": "compartment_17957", "id": "reaction_10774098", "reactome": "R-SCE-2046087", "name": "Translocation of tetracosahexaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046054", "species_211579" ], "products": [ "species_2046047", "species_211606", "species_426639" ], "modifiers": [ [ "species_10768821", "catalyst" ] ], "additional_components": [ "YPL147W" ] }, "reaction_10767537": { "compartment": "compartment_70101", "id": "reaction_10767537", "reactome": "R-SCE-200740", "name": "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200640", "species_29356" ], "products": [ "species_111353" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10769032": { "compartment": "compartment_17951", "id": "reaction_10769032", "reactome": "R-SCE-389889", "name": "ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389893", "species_113535" ], "products": [ "species_389894", "species_113575" ], "modifiers": [ [ "species_10769029", "catalyst" ] ], "additional_components": [ "P13711", "YGL205W", "species_113596" ] }, "reaction_10766890": { "compartment": "compartment_70101", "id": "reaction_10766890", "reactome": "R-SCE-194642", "name": "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194735", "species_29360" ], "products": [ "species_70106", "species_73473", "species_113528", "species_194667" ], "modifiers": [ [ "species_10766887", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10764323": { "compartment": "compartment_70101", "id": "reaction_10764323", "reactome": "R-SCE-76590", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76577", "species_29356" ], "products": [ "species_29602", "species_31633" ], "modifiers": [ [ "species_10764320", "catalyst" ] ], "additional_components": [ "P38150", "YJL070C", "P15274", "YML035C", "P40361", "YJL070C" ] }, "reaction_10761802": { "compartment": "compartment_70101", "id": "reaction_10761802", "reactome": "R-SCE-71218", "name": "3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_30487" ], "products": [ "species_36027" ], "modifiers": [ [ "species_10761799", "catalyst" ] ], "additional_components": [ "P47096", "YJR025C", "species_111793" ] }, "reaction_10765675": { "compartment": "compartment_7660", "id": "reaction_10765675", "reactome": "R-SCE-163748", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10764091" ], "modifiers": [], "additional_components": [ "YDL052C" ] }, "reaction_10779627": { "compartment": "compartment_12045", "id": "reaction_10779627", "reactome": "R-SCE-5689000", "name": "AADAC deacetylates PHEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5689006", "species_29356" ], "products": [ "species_5688995", "species_5689001" ], "modifiers": [ [ "species_10779624", "catalyst" ] ], "additional_components": [ "YGR263C" ] }, "reaction_10781992": { "compartment": "compartment_70101", "id": "reaction_10781992", "reactome": "R-SCE-6787329", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_112016" ], "products": [ "species_73578" ], "modifiers": [ [ "species_10761119", "catalyst" ] ], "additional_components": [ "Q03262", "YMR278W", "species_109496" ] }, "reaction_10763550": { "compartment": "compartment_70101", "id": "reaction_10763550", "reactome": "R-SCE-74213", "name": "APRT catalyzes the conversion of adenine to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_83951" ], "products": [ "species_111294", "species_76577" ], "modifiers": [ [ "species_10763547", "catalyst" ] ], "additional_components": [ "P49435", "YML022W" ] }, "reaction_10766581": { "compartment": "compartment_5460", "id": "reaction_10766581", "reactome": "R-SCE-189442", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70958", "species_159549", "species_113529" ], "products": [ "species_29374", "species_189466", "species_29376" ], "modifiers": [ [ "species_10766578", "catalyst" ], [ "species_189444", "inhibitor" ] ], "additional_components": [ "P09950", "YDR232W" ] }, "reaction_10787970": { "compartment": "compartment_70101", "id": "reaction_10787970", "reactome": "R-SCE-9012374", "name": "VDAC1 transports PYR from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398" ], "products": [ "species_9012375" ], "modifiers": [ [ "species_10777036", "catalyst" ] ], "additional_components": [ "P04840", "POR1", "P40478", "YIL114C" ] }, "reaction_10780397": { "compartment": "compartment_17951", "id": "reaction_10780397", "reactome": "R-SCE-5690042", "name": "Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_5690520" ], "products": [ "species_193514", "species_5690539" ], "modifiers": [ [ "species_10766854", "catalyst" ] ], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "species_382577", "CHEBI:59554", "YJR019C" ] }, "reaction_10761921": { "compartment": "compartment_5460", "id": "reaction_10761921", "reactome": "R-SCE-71401", "name": "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113594", "species_113526" ], "products": [ "species_29376", "species_70958", "species_29362" ], "modifiers": [ [ "species_10761760", "catalyst" ] ], "additional_components": [ "species_29480", "P20967", "YIL125W", "CHEBI:17460", "P09624", "YFL018C", "species_113596", "P19262", "YDR148C" ] }, "reaction_10773344": { "compartment": "compartment_70101", "id": "reaction_10773344", "reactome": "R-SCE-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1498751" ], "products": [ "species_29370", "species_428686" ], "modifiers": [ [ "species_10773341", "catalyst" ] ], "additional_components": [ "P20485", "YLR133W", "Q03764", "YDR147W" ] }, "reaction_10769039": { "compartment": "compartment_17951", "id": "reaction_10769039", "reactome": "R-SCE-389891", "name": "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389893", "species_113535" ], "products": [ "species_389894", "species_113575" ], "modifiers": [ [ "species_10769036", "catalyst" ] ], "additional_components": [ "P13711", "YGL205W", "species_113596" ] }, "reaction_10769019": { "compartment": "compartment_17951", "id": "reaction_10769019", "reactome": "R-SCE-389842", "name": "HAO1 tetramer oxidizes glycolate to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389822", "species_113535" ], "products": [ "species_389678", "species_113575" ], "modifiers": [ [ "species_10769016", "catalyst" ] ], "additional_components": [ "species_73524", "P00175", "CYB2" ] }, "reaction_10785562": { "compartment": "compartment_984", "id": "reaction_10785562", "reactome": "R-SCE-8851356", "name": "NTPDase5 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936165", "species_109276" ], "products": [ "species_109277", "species_351626", "species_8851369" ], "modifiers": [ [ "species_10785559", "catalyst" ] ], "additional_components": [ "species_29420", "species_29370", "species_110094", "species_110096", "species_109395", "species_76577", "species_109402", "species_113578", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10773047": { "compartment": "compartment_12045", "id": "reaction_10773047", "reactome": "R-SCE-1482667", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498738", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10773037", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10774299": { "compartment": "compartment_5460", "id": "reaction_10774299", "reactome": "R-SCE-2395517", "name": "NADPH transfers electrons to FDXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_10774295", "species_113529" ], "products": [ "species_10774293", "species_113563" ], "modifiers": [], "additional_components": [ "P48360", "YDR376W", "species_113596", "P48360", "YDR376W", "species_31649" ] }, "reaction_10761456": { "compartment": "compartment_5460", "id": "reaction_10761456", "reactome": "R-SCE-70560", "name": "carbamoyl phosphate + ornithine => citrulline + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29676", "species_113585" ], "products": [ "species_113548", "species_113567" ], "modifiers": [ [ "species_10761453", "catalyst" ] ], "additional_components": [ "P05150", "YJL088W" ] }, "reaction_10763572": { "compartment": "compartment_70101", "id": "reaction_10763572", "reactome": "R-SCE-74255", "name": "Guanine + H2O => Xanthine + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29356", "species_83956" ], "products": [ "species_30064", "species_31633" ], "modifiers": [ [ "species_10763569", "catalyst" ] ], "additional_components": [ "species_158417", "Q07729", "YDL238C" ] }, "reaction_10773257": { "compartment": "compartment_70616", "id": "reaction_10773257", "reactome": "R-SCE-1483063", "name": "PG and CDP-DAG are converted to CL by CRLS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_1524064" ], "products": [ "species_1524067", "species_1524072" ], "modifiers": [ [ "species_10772962", "catalyst" ] ], "additional_components": [ "YDL142C" ] }, "reaction_10785439": { "compartment": "compartment_17957", "id": "reaction_10785439", "reactome": "R-SCE-8848246", "name": "DBI, ACBD7 bind MCFA-CoA and LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848288", "species_10785433" ], "products": [ "species_10785437" ], "modifiers": [], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "YGR037C", "CHEBI:33184", "CHEBI:61907", "P31787", "YGR037C" ] }, "reaction_10765739": { "compartment": "compartment_70616", "id": "reaction_10765739", "reactome": "R-SCE-164651", "name": "Electron transfer from ubiquinol to cytochrome c of complex III", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76633", "species_10765569", "species_113529", "species_73663" ], "products": [ "species_76633", "species_10765567", "species_163953", "species_73663" ], "modifiers": [ [ "species_10765736", "catalyst" ] ], "additional_components": [ "P00045", "YEL039C", "P00044", "YJR048W", "CHEBI:38574", "P00045", "YEL039C", "P00044", "YJR048W", "CHEBI:38573", "P11914", "MAS2", "P00128", "YDR529C", "P10507", "MAS1", "P07256", "YBL045C", "P08067", "YEL024W", "P00163", "Q0105", "P07143", "CYT1", "P22289", "YGR183C", "P00127", "YFR033C", "P08525", "YJL166W" ] }, "reaction_10766892": { "compartment": "compartment_70101", "id": "reaction_10766892", "reactome": "R-SCE-194669", "name": "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194723", "species_29368" ], "products": [ "species_29366", "species_29356", "species_194657" ], "modifiers": [ [ "species_10766882", "catalyst" ] ], "additional_components": [ "YGR060W" ] }, "reaction_10789271": { "compartment": "compartment_70101", "id": "reaction_10789271", "reactome": "R-SCE-9717834", "name": "GGPS1 hexamer transfers IPPP to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191324" ], "products": [ "species_191409", "species_111294" ], "modifiers": [ [ "species_10789265", "catalyst" ] ], "additional_components": [ "Q12051", "YPL069C", "species_109496" ] }, "reaction_10775602": { "compartment": "compartment_70101", "id": "reaction_10775602", "reactome": "R-SCE-3322019", "name": "Autoglucosylation of GYG2 complexed with GYS2-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775597" ], "products": [ "species_110096", "species_10775599" ], "modifiers": [ [ "species_10775597", "catalyst" ] ], "additional_components": [ "P27472", "YLR258W", "P47011", "YJL137C", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P27472", "YLR258W", "P47011", "YJL137C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10775616": { "compartment": "compartment_70101", "id": "reaction_10775616", "reactome": "R-SCE-3322057", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775609" ], "products": [ "species_10775614" ], "modifiers": [ [ "species_10775557", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "YEL011W" ] }, "reaction_10785555": { "compartment": "compartment_17963", "id": "reaction_10785555", "reactome": "R-SCE-8851234", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851233", "species_2022884" ], "products": [ "species_425969", "species_8851224", "species_8851226" ], "modifiers": [ [ "species_10785549", "catalyst" ] ], "additional_components": [ "species_29494", "species_30187", "species_29438", "species_110614", "species_29420", "CHEBI:58369", "species_110094", "species_110096", "P40009", "YER005W", "species_74016" ] }, "reaction_10766160": { "compartment": "compartment_5460", "id": "reaction_10766160", "reactome": "R-SCE-169270", "name": "ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766149", "species_73663" ], "products": [ "species_76633", "species_10766147" ], "modifiers": [ [ "species_10766157", "catalyst" ] ], "additional_components": [ "species_76577", "species_31649", "Q12480", "YPR004C", "P42940", "YGR207C", "species_76577", "Q12480", "YPR004C", "P42940", "YGR207C", "species_113596", "YOR356W" ] }, "reaction_10769932": { "compartment": "compartment_70101", "id": "reaction_10769932", "reactome": "R-SCE-428696", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10769929", "catalyst" ] ], "additional_components": [ "Q05521", "YDR284C", "Q04396", "YDR503C" ] }, "reaction_10781083": { "compartment": "compartment_12045", "id": "reaction_10781083", "reactome": "R-SCE-5692261", "name": "ALDH3A2-1 oxidises HD2NAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_29356", "species_428671" ], "products": [ "species_70106", "species_73473", "species_3632881" ], "modifiers": [ [ "species_10781080", "catalyst" ] ], "additional_components": [ "Q04458", "YMR110C" ] }, "reaction_10770608": { "compartment": "compartment_5460", "id": "reaction_10770608", "reactome": "R-SCE-449911", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113539", "species_113593" ], "products": [ "species_159448", "species_159450", "species_113559" ], "modifiers": [ [ "species_10770605", "catalyst" ] ], "additional_components": [ "YAL054C" ] }, "reaction_10775516": { "compartment": "compartment_70101", "id": "reaction_10775516", "reactome": "R-SCE-3322001", "name": "GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775511" ], "products": [ "species_110096", "species_10775513" ], "modifiers": [ [ "species_10775511", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10773288": { "compartment": "compartment_70616", "id": "reaction_10773288", "reactome": "R-SCE-1483165", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110577", "species_1524101" ], "products": [ "species_1524064", "species_159450" ], "modifiers": [ [ "species_10773285", "catalyst" ] ], "additional_components": [ "YBR029C" ] }, "reaction_10763560": { "compartment": "compartment_70101", "id": "reaction_10763560", "reactome": "R-SCE-74242", "name": "PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500172", "species_29372" ], "products": [ "species_113599", "species_500244" ], "modifiers": [ [ "species_10763557", "catalyst" ] ], "additional_components": [ "CHEBI:28997", "CHEBI:17596", "species_112016", "CHEBI:58576", "Q05788", "YLR209C" ] }, "reaction_10789066": { "compartment": "compartment_70101", "id": "reaction_10789066", "reactome": "R-SCE-9678749", "name": "IMPDH tetramers binds IMPDH inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763342", "species_9678719" ], "products": [ "species_10763345" ], "modifiers": [], "additional_components": [ "P38697", "YHR216W", "P50095", "YLR432W", "P50094", "YML056C", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842", "P38697", "YHR216W", "P50095", "YLR432W", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842", "P50094", "YML056C" ] }, "reaction_10773306": { "compartment": "compartment_12045", "id": "reaction_10773306", "reactome": "R-SCE-1483182", "name": "PC is hydrolyzed to PA and choline by PLD1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_264618", "species_426755" ], "modifiers": [ [ "species_10773301", "catalyst" ] ], "additional_components": [ "YKR031C" ] }, "reaction_10763387": { "compartment": "compartment_70101", "id": "reaction_10763387", "reactome": "R-SCE-73812", "name": "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111354", "species_29472", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29370", "species_111369", "species_29404", "species_29372" ], "modifiers": [ [ "species_10763384", "catalyst" ] ], "additional_components": [ "YGR061C" ] }, "reaction_10763132": { "compartment": "compartment_70101", "id": "reaction_10763132", "reactome": "R-SCE-73599", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500759", "species_113592" ], "products": [ "species_29370", "species_500761" ], "modifiers": [ [ "species_10763129", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:16704", "species_109395", "species_109402", "Q12084", "YDR020C" ] }, "reaction_10775579": { "compartment": "compartment_70101", "id": "reaction_10775579", "reactome": "R-SCE-3322009", "name": "GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775574" ], "products": [ "species_110096", "species_10775576" ], "modifiers": [ [ "species_10775574", "catalyst" ] ], "additional_components": [ "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C" ] }, "reaction_10789268": { "compartment": "compartment_70101", "id": "reaction_10789268", "reactome": "R-SCE-9717830", "name": "GGPS1 hexamer transfers IPPP to GPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191409" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10789265", "catalyst" ] ], "additional_components": [ "Q12051", "YPL069C", "species_109496" ] }, "reaction_10779036": { "compartment": "compartment_12045", "id": "reaction_10779036", "reactome": "R-SCE-5676637", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676631" ], "products": [ "species_5676634", "species_29356" ], "modifiers": [ [ "species_10779031", "catalyst" ] ], "additional_components": [ "YJL097W" ] }, "reaction_10788222": { "compartment": "compartment_70101", "id": "reaction_10788222", "reactome": "R-SCE-9014766", "name": "PXLP-K56-SRR dimer isomerises L-Ser to D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_376186" ], "modifiers": [ [ "species_10788216", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "P36007", "YKL218C" ] }, "reaction_10764143": { "compartment": "compartment_70101", "id": "reaction_10764143", "reactome": "R-SCE-75889", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_75970" ], "products": [ "species_29360", "species_76114" ], "modifiers": [ [ "species_10764140", "catalyst" ] ], "additional_components": [ "P41911", "YOL059W", "Q00055", "YDL022W" ] }, "reaction_10763361": { "compartment": "compartment_70101", "id": "reaction_10763361", "reactome": "R-SCE-73798", "name": "AICAR + 10-Formyl-THF => FAICAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111409", "species_419151" ], "products": [ "species_111427", "species_111355" ], "modifiers": [ [ "species_10763355", "catalyst" ] ], "additional_components": [ "P38009", "YMR120C" ] }, "reaction_10763112": { "compartment": "compartment_70101", "id": "reaction_10763112", "reactome": "R-SCE-73580", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_73578" ], "products": [ "species_73566", "species_76577" ], "modifiers": [ [ "species_10763109", "catalyst" ] ], "additional_components": [ "P38063", "YBL068W", "P32895", "YKL181W", "P38689", "YHL011C", "Q12265", "YOL061W", "P38620", "YER099C" ] }, "reaction_10762072": { "compartment": "compartment_70101", "id": "reaction_10762072", "reactome": "R-SCE-71670", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29370", "species_29492" ], "products": [ "species_113592", "species_29398" ], "modifiers": [ [ "species_10762069", "catalyst" ], [ "species_30014", "catalyst" ], [ "species_76183", "inhibitor" ], [ "species_30389", "inhibitor" ], [ "species_29358", "inhibitor" ] ], "additional_components": [ "P00549", "YAL038W", "species_74126", "species_109496", "P52489", "YOR347C" ] }, "reaction_10775607": { "compartment": "compartment_70101", "id": "reaction_10775607", "reactome": "R-SCE-3322025", "name": "Autoglucosylation of GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775604", "species_29410" ], "products": [ "species_110096", "species_10775511" ], "modifiers": [ [ "species_10775604", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P27472", "YLR258W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P27472", "YLR258W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10785160": { "compartment": "compartment_70101", "id": "reaction_10785160", "reactome": "R-SCE-6813749", "name": "ALDH1A1 oxidises GA to DGA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30393", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_6799497" ], "modifiers": [ [ "species_10762101", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10773606": { "compartment": "compartment_20699", "id": "reaction_10773606", "reactome": "R-SCE-1676185", "name": "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10773603", "catalyst" ] ], "additional_components": [ "P37297", "YLR305C", "P42951", "YJL100W" ] }, "reaction_10776478": { "compartment": "compartment_70101", "id": "reaction_10776478", "reactome": "R-SCE-4167511", "name": "HLCS biotinylates ACACB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_113592", "species_10776476" ], "products": [ "species_10767433", "species_111294", "species_76577" ], "modifiers": [ [ "species_10774830", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527", "Q00955", "YNR016C", "species_113527", "YDL141W" ] }, "reaction_10767652": { "compartment": "compartment_20699", "id": "reaction_10767652", "reactome": "R-SCE-202132", "name": "depalmitoylated eNOS translocates from plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767646" ], "products": [ "species_10767650" ], "modifiers": [], "additional_components": [ "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_29870", "species_113596", "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_29870", "species_113596" ] }, "reaction_10767486": { "compartment": "compartment_70101", "id": "reaction_10767486", "reactome": "R-SCE-200644", "name": "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_200739" ], "products": [ "species_70106", "species_29364", "species_200640" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10773135": { "compartment": "compartment_12045", "id": "reaction_10773135", "reactome": "R-SCE-1482828", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2[4]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10773132", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10769054": { "compartment": "compartment_17951", "id": "reaction_10769054", "reactome": "R-SCE-390251", "name": "HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390248", "species_192307" ], "products": [ "species_193465", "species_390241", "species_192305" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10767494": { "compartment": "compartment_876", "id": "reaction_10767494", "reactome": "R-SCE-200646", "name": "Cytosolic folate export across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965" ], "products": [ "species_200716" ], "modifiers": [ [ "species_10767491", "catalyst" ] ], "additional_components": [ "YJL163C" ] }, "reaction_10768943": { "compartment": "compartment_17951", "id": "reaction_10768943", "reactome": "R-SCE-389639", "name": "phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389537", "species_389615", "species_113535" ], "products": [ "species_389594", "species_389583", "species_389536" ], "modifiers": [ [ "species_10768940", "catalyst" ] ], "additional_components": [ "P47181", "YJR154W", "species_111793" ] }, "reaction_10788342": { "compartment": "compartment_70101", "id": "reaction_10788342", "reactome": "R-SCE-9018877", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023708", "species_29356" ], "products": [ "species_9023712" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10763152": { "compartment": "compartment_70101", "id": "reaction_10763152", "reactome": "R-SCE-73608", "name": "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500829", "species_29356" ], "products": [ "species_31633", "species_500430" ], "modifiers": [ [ "species_10763149", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:15698", "CHEBI:16704", "CHEBI:16450", "species_158417", "Q06549", "YLR245C" ] }, "reaction_10772970": { "compartment": "compartment_12045", "id": "reaction_10772970", "reactome": "R-SCE-1482571", "name": "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498738", "species_29356" ], "products": [ "species_1524023", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10786551": { "compartment": "compartment_70101", "id": "reaction_10786551", "reactome": "R-SCE-8869606", "name": "NMRK1 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10786548", "catalyst" ] ], "additional_components": [ "YNL129W" ] }, "reaction_10773475": { "compartment": "compartment_876", "id": "reaction_10773475", "reactome": "R-SCE-1675810", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_1806240" ], "modifiers": [ [ "species_10773418", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10781631": { "compartment": "compartment_5460", "id": "reaction_10781631", "reactome": "R-SCE-5696091", "name": "ALDH1B1 tetramer oxidises CH3CHO to CH3COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_113532" ], "products": [ "species_113539", "species_29362", "species_113529" ], "modifiers": [ [ "species_10781628", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10770185": { "compartment": "compartment_17906", "id": "reaction_10770185", "reactome": "R-SCE-434382", "name": "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_3632881", "species_113592" ], "products": [ "species_111294", "species_76577", "species_200993" ], "modifiers": [ [ "species_10770182", "catalyst" ] ], "additional_components": [ "P47912", "YMR246W", "P39002", "YIL009W", "P30624", "YOR317W" ] }, "reaction_10767476": { "compartment": "compartment_70101", "id": "reaction_10767476", "reactome": "R-SCE-200555", "name": "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10764049", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "P32874", "YMR207C" ] }, "reaction_10782610": { "compartment": "compartment_5460", "id": "reaction_10782610", "reactome": "R-SCE-6792572", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781283", "species_10782600" ], "products": [ "species_10782602", "species_10781285" ], "modifiers": [ [ "species_10782607", "catalyst" ] ], "additional_components": [ "YAL044C", "P32473", "YBR221C", "species_29480", "P20967", "YIL125W", "CHEBI:17460", "P16387", "YER178W", "P09624", "YFL018C", "species_113596", "P19262", "YDR148C", "P12695", "YNL071W", "P32473", "YBR221C", "species_29480", "P20967", "YIL125W", "P16387", "YER178W", "CHEBI:17460", "P09624", "YFL018C", "species_113596", "P12695", "YNL071W", "P19262", "YDR148C", "YAL044C", "YJL046W" ] }, "reaction_10762216": { "compartment": "compartment_70101", "id": "reaction_10762216", "reactome": "R-SCE-71802", "name": "D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_29370", "species_30533" ], "modifiers": [ [ "species_10762213", "catalyst" ], [ "species_30533", "catalyst" ] ], "additional_components": [ "Q12471", "YOL136C", "Q06137", "YLR345W", "P32604", "YJL155C" ] }, "reaction_10773173": { "compartment": "compartment_12045", "id": "reaction_10773173", "reactome": "R-SCE-1482920", "name": "PG is hydrolyzed to 2-acyl LPG by PLA2[14]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498730", "species_1524021" ], "modifiers": [ [ "species_10773170", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10785552": { "compartment": "compartment_17963", "id": "reaction_10785552", "reactome": "R-SCE-8851225", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851224", "species_2022884" ], "products": [ "species_8851227", "species_425969", "species_8851226" ], "modifiers": [ [ "species_10785549", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58369", "species_110094", "species_110096", "species_109366", "species_109395", "species_109402", "species_113578", "P40009", "YER005W", "species_74016" ] }, "reaction_10765673": { "compartment": "compartment_7660", "id": "reaction_10765673", "reactome": "R-SCE-163743", "name": "Transcriptional activation of Acetyl-CoA carboxylase by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10765671" ], "modifiers": [], "additional_components": [ "Q00955", "YNR016C", "P32874", "YMR207C" ] }, "reaction_10784150": { "compartment": "compartment_5460", "id": "reaction_10784150", "reactome": "R-SCE-6801462", "name": "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6801458", "species_113521" ], "products": [ "species_5389850" ], "modifiers": [ [ "species_10784132", "catalyst" ] ], "additional_components": [ "YBR084W" ] }, "reaction_10769083": { "compartment": "compartment_17947", "id": "reaction_10769083", "reactome": "R-SCE-390393", "name": "Peroxisomal uptake of very long-chain fatty acyl CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390394" ], "products": [ "species_390260" ], "modifiers": [ [ "species_10768823", "catalyst" ] ], "additional_components": [ "P41909", "YPL147W" ] }, "reaction_10766760": { "compartment": "compartment_70101", "id": "reaction_10766760", "reactome": "R-SCE-191405", "name": "Two FPP molecules dimerize to form presqualene diphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191385" ], "products": [ "species_191265", "species_111294" ], "modifiers": [ [ "species_10766755", "catalyst" ] ], "additional_components": [ "P29704", "YHR190W", "species_109496" ] }, "reaction_10781904": { "compartment": "compartment_5460", "id": "reaction_10781904", "reactome": "R-SCE-6784224", "name": "PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784215" ], "products": [ "species_6784241" ], "modifiers": [ [ "species_10781901", "catalyst" ] ], "additional_components": [ "P09368", "YLR142W", "species_113596" ] }, "reaction_10763162": { "compartment": "compartment_70101", "id": "reaction_10763162", "reactome": "R-SCE-73647", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29494", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_110614", "species_29372" ], "modifiers": [ [ "species_10763159", "catalyst" ] ], "additional_components": [ "P28274", "YBL039C" ] }, "reaction_10786543": { "compartment": "compartment_70101", "id": "reaction_10786543", "reactome": "R-SCE-8869241", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_426639" ], "products": [ "species_426658", "species_426755" ], "modifiers": [ [ "species_10786540", "catalyst" ] ], "additional_components": [ "YOR022C" ] }, "reaction_10767496": { "compartment": "compartment_70101", "id": "reaction_10767496", "reactome": "R-SCE-200651", "name": "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_200739" ], "products": [ "species_200736", "species_197969" ], "modifiers": [ [ "species_10761810", "catalyst" ] ], "additional_components": [ "P37292", "YBR263W" ] }, "reaction_10777429": { "compartment": "compartment_17957", "id": "reaction_10777429", "reactome": "R-SCE-5250531", "name": "ARV1 transports CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193384" ], "products": [ "species_171095" ], "modifiers": [ [ "species_10777426", "catalyst" ] ], "additional_components": [ "YLR242C" ] }, "reaction_10767533": { "compartment": "compartment_876", "id": "reaction_10767533", "reactome": "R-SCE-200729", "name": "SLC46A1 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200716" ], "products": [ "species_197965" ], "modifiers": [ [ "species_10767491", "catalyst" ] ], "additional_components": [ "YJL163C" ] }, "reaction_10781613": { "compartment": "compartment_17906", "id": "reaction_10781613", "reactome": "R-SCE-5696074", "name": "AGK:Mg2+ phosphorylates MAG, DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696069", "species_5696066" ], "products": [ "species_5696026", "species_5696037" ], "modifiers": [ [ "species_10781610", "catalyst" ] ], "additional_components": [ "species_6797635", "species_6814795", "species_1602448", "species_417891", "Q12246", "YOR171C", "P47045", "TIM54", "species_109496", "Q06147", "YLR260W" ] }, "reaction_10788346": { "compartment": "compartment_70101", "id": "reaction_10788346", "reactome": "R-SCE-9020253", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024781", "species_29356" ], "products": [ "species_9024809" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "CHEBI:138649", "CHEBI:138648", "species_158417", "Q10740", "YNL045W" ] }, "reaction_10781648": { "compartment": "compartment_5460", "id": "reaction_10781648", "reactome": "R-SCE-5696839", "name": "MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_6801451", "species_113593" ], "products": [ "species_5389850", "species_113548", "species_113581" ], "modifiers": [ [ "species_10781645", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10784754": { "compartment": "compartment_70101", "id": "reaction_10784754", "reactome": "R-SCE-6809680", "name": "MTMR12 binds MTM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773463", "species_10784750" ], "products": [ "species_10784752" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10781641": { "compartment": "compartment_12045", "id": "reaction_10781641", "reactome": "R-SCE-5696448", "name": "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696449", "species_6782195" ], "products": [ "species_76194", "species_1500596" ], "modifiers": [ [ "species_10781638", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10789150": { "compartment": "compartment_70101", "id": "reaction_10789150", "reactome": "R-SCE-9695949", "name": "SPHK2 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_29370", "species_428203" ], "modifiers": [ [ "species_10769846", "catalyst" ], [ "species_10789148", "inhibitor" ] ], "additional_components": [ "Q12246", "YOR171C", "P47045", "TIM54", "Q06147", "YLR260W", "LigandDisplayForward?ligandId=6625", "Q12246", "YOR171C", "LigandDisplayForward?ligandId=10641", "P47045", "TIM54", "LigandDisplayForward?ligandId=10219", "LigandDisplayForward?ligandId=6624", "Q06147", "YLR260W" ] }, "reaction_10781989": { "compartment": "compartment_17951", "id": "reaction_10781989", "reactome": "R-SCE-6786720", "name": "DECR2 reduces LCtE-CoA to t3enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_113602", "species_6786723" ], "products": [ "species_389556", "species_6786715" ], "modifiers": [ [ "species_10781986", "catalyst" ] ], "additional_components": [ "YNL202W" ] }, "reaction_10773159": { "compartment": "compartment_12045", "id": "reaction_10773159", "reactome": "R-SCE-1482889", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_76194", "species_1500594" ], "modifiers": [ [ "species_10771182", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10767517": { "compartment": "compartment_70616", "id": "reaction_10767517", "reactome": "R-SCE-200680", "name": "SLC25A32 transports THF from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111355" ], "products": [ "species_200671" ], "modifiers": [ [ "species_10767514", "catalyst" ] ], "additional_components": [ "YIL134W" ] }, "reaction_10768215": { "compartment": "compartment_70101", "id": "reaction_10768215", "reactome": "R-SCE-265295", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10768212", "catalyst" ] ], "additional_components": [ "YKL117W" ] }, "reaction_10774833": { "compartment": "compartment_70101", "id": "reaction_10774833", "reactome": "R-SCE-2993802", "name": "HLCS biotinylates PC:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_10774820", "species_113592" ], "products": [ "species_10774825", "species_111294", "species_76577" ], "modifiers": [ [ "species_10774830", "catalyst" ] ], "additional_components": [ "P11154", "YGL062W", "species_113527", "P11154", "YGL062W", "species_113527", "YDL141W" ] }, "reaction_10781981": { "compartment": "compartment_70101", "id": "reaction_10781981", "reactome": "R-SCE-6786650", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_29356" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10781978", "catalyst" ] ], "additional_components": [ "Q12204", "YOR022C" ] }, "reaction_10773485": { "compartment": "compartment_12045", "id": "reaction_10773485", "reactome": "R-SCE-1675813", "name": "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_29370", "species_1806234" ], "modifiers": [ [ "species_10773482", "catalyst" ] ], "additional_components": [ "P37297", "YLR305C", "P42951", "YJL100W" ] }, "reaction_10786556": { "compartment": "compartment_70101", "id": "reaction_10786556", "reactome": "R-SCE-8869607", "name": "NMRK2 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10786553", "catalyst" ] ], "additional_components": [ "YNL129W" ] }, "reaction_10761919": { "compartment": "compartment_5460", "id": "reaction_10761919", "reactome": "R-SCE-71397", "name": "lipo-PDH decarboxylates PYR to Ac-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113557", "species_113526" ], "products": [ "species_29376", "species_29362", "species_113559" ], "modifiers": [ [ "species_10761916", "catalyst" ] ], "additional_components": [ "P32473", "YBR221C", "species_29480", "P16387", "YER178W", "P09624", "YFL018C", "species_113596", "P12695", "YNL071W" ] }, "reaction_10762130": { "compartment": "compartment_70101", "id": "reaction_10762130", "reactome": "R-SCE-71707", "name": "ethanol + NAD+ => acetaldehyde + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30203", "species_29360" ], "products": [ "species_70106", "species_73473", "species_29510" ], "modifiers": [ [ "species_10762127", "catalyst" ] ], "additional_components": [ "species_158417", "P32771", "YDL168W" ] }, "reaction_10773425": { "compartment": "compartment_876", "id": "reaction_10773425", "reactome": "R-SCE-1675773", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_202247" ], "products": [ "species_29370", "species_179838" ], "modifiers": [ [ "species_10773418", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10773535": { "compartment": "compartment_171062", "id": "reaction_10773535", "reactome": "R-SCE-1675939", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806200" ], "modifiers": [ [ "species_10773532", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "species_113527" ] }, "reaction_10773153": { "compartment": "compartment_12045", "id": "reaction_10773153", "reactome": "R-SCE-1482867", "name": "DLCL is acylated to MLCL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524080", "species_1500578" ], "products": [ "species_76194", "species_1524069" ], "modifiers": [ [ "species_10764105", "catalyst" ] ], "additional_components": [ "YBR042C" ] }, "reaction_10767135": { "compartment": "compartment_70101", "id": "reaction_10767135", "reactome": "R-SCE-198563", "name": "IDO1 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29500" ], "products": [ "species_33179" ], "modifiers": [ [ "species_10767132", "catalyst" ] ], "additional_components": [ "P47125", "YJR078W", "species_189444" ] }, "reaction_10769042": { "compartment": "compartment_17951", "id": "reaction_10769042", "reactome": "R-SCE-389986", "name": "trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389894", "species_141343" ], "products": [ "species_389982" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10773514": { "compartment": "compartment_876", "id": "reaction_10773514", "reactome": "R-SCE-1675836", "name": "PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806276", "species_29372" ], "modifiers": [ [ "species_10773511", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "Q08227", "YOL065C", "P50942", "YNL106C" ] }, "reaction_10766591": { "compartment": "compartment_5460", "id": "reaction_10766591", "reactome": "R-SCE-189465", "name": "FECH binds Fe2+ to PRIN9 to form heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189487", "species_113531" ], "products": [ "species_189444", "species_113529" ], "modifiers": [ [ "species_10766588", "catalyst" ], [ "species_391232", "inhibitor" ] ], "additional_components": [ "P16622", "YOR176W" ] }, "reaction_10766702": { "compartment": "compartment_70101", "id": "reaction_10766702", "reactome": "R-SCE-191303", "name": "FDPS dimer transfers IPPP to GPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191409" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10766699", "catalyst" ] ], "additional_components": [ "P08524", "YJL167W", "species_109496" ] }, "reaction_10786562": { "compartment": "compartment_70101", "id": "reaction_10786562", "reactome": "R-SCE-8869633", "name": "NMRK1 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_70106", "species_29370", "species_8869353" ], "modifiers": [ [ "species_10786548", "catalyst" ] ], "additional_components": [ "YNL129W" ] }, "reaction_10766720": { "compartment": "compartment_70101", "id": "reaction_10766720", "reactome": "R-SCE-191352", "name": "HMGCR dimer reduces bHMG-CoA to MVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191374" ], "products": [ "species_76194", "species_29366", "species_191424" ], "modifiers": [ [ "species_10766717", "catalyst" ] ], "additional_components": [ "P12683", "YML075C" ] }, "reaction_10767740": { "compartment": "compartment_20699", "id": "reaction_10767740", "reactome": "R-SCE-203700", "name": "eNOS translocation from Golgi to Caveolae", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767716" ], "products": [ "species_10767589" ], "modifiers": [], "additional_components": [ "YHR042W", "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_113596" ] }, "reaction_10772965": { "compartment": "compartment_70616", "id": "reaction_10772965", "reactome": "R-SCE-1482546", "name": "2-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524047", "species_1524038" ], "products": [ "species_1524042", "species_29374" ], "modifiers": [ [ "species_10772962", "catalyst" ] ], "additional_components": [ "YDL142C" ] }, "reaction_10769833": { "compartment": "compartment_70101", "id": "reaction_10769833", "reactome": "R-SCE-428185", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428163", "species_428139" ], "products": [ "species_76194", "species_428126" ], "modifiers": [ [ "species_10769830", "catalyst" ] ], "additional_components": [ "P38703", "YHL003C", "P28496", "YKL008C" ] }, "reaction_10787624": { "compartment": "compartment_5460", "id": "reaction_10787624", "reactome": "R-SCE-8952873", "name": "MECR dimer reduces tdec2-CoA to DEC-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_77343", "species_113529" ], "products": [ "species_113563", "species_77308" ], "modifiers": [ [ "species_10787621", "catalyst" ] ], "additional_components": [ "P38071", "YBR026C" ] }, "reaction_10786524": { "compartment": "compartment_12045", "id": "reaction_10786524", "reactome": "R-SCE-8867876", "name": "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_392417" ], "products": [ "species_1806234", "species_33625" ], "modifiers": [ [ "species_10786521", "catalyst" ] ], "additional_components": [ "P38755", "YHR001W", "P35844", "YPL145C", "P35843", "YOR237W" ] }, "reaction_10769008": { "compartment": "compartment_17951", "id": "reaction_10769008", "reactome": "R-SCE-389826", "name": "glyoxylate + NADPH + H+ => glycolate + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_113602", "species_389678" ], "products": [ "species_389822", "species_389556" ], "modifiers": [ [ "species_10769005", "catalyst" ] ], "additional_components": [ "YPL113C" ] }, "reaction_10785535": { "compartment": "compartment_984", "id": "reaction_10785535", "reactome": "R-SCE-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8936166" ], "products": [ "species_109277", "species_351626", "species_8851092" ], "modifiers": [ [ "species_10785532", "catalyst" ] ], "additional_components": [ "species_29494", "species_113592", "species_2509836", "species_29438", "species_110614", "species_29420", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10786911": { "compartment": "compartment_70101", "id": "reaction_10786911", "reactome": "R-SCE-8876889", "name": "Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10767435", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527" ] }, "reaction_10769786": { "compartment": "compartment_70101", "id": "reaction_10769786", "reactome": "R-SCE-428123", "name": "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_428182" ], "products": [ "species_29366", "species_428163" ], "modifiers": [ [ "species_10769783", "catalyst" ] ], "additional_components": [ "YBR265W" ] }, "reaction_10785504": { "compartment": "compartment_984", "id": "reaction_10785504", "reactome": "R-SCE-8850846", "name": "NTPDase1 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785501", "catalyst" ] ], "additional_components": [ "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10761841": { "compartment": "compartment_70101", "id": "reaction_10761841", "reactome": "R-SCE-71296", "name": "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31467", "species_29356" ], "products": [ "species_29996" ], "modifiers": [ [ "species_10761838", "catalyst" ] ], "additional_components": [ "YHR163W" ] }, "reaction_10776243": { "compartment": "compartment_70101", "id": "reaction_10776243", "reactome": "R-SCE-3780997", "name": "PPP1R3C binds to glycogen:GYG2:GYS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775586", "species_10776211" ], "products": [ "species_10776213" ], "modifiers": [], "additional_components": [ "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "Q06216", "YLR273C", "P28006", "YOR178C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10778265": { "compartment": "compartment_7660", "id": "reaction_10778265", "reactome": "R-SCE-5649799", "name": "DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10778250" ], "products": [ "species_10778263", "species_77502" ], "modifiers": [ [ "species_10778255", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YDR440W" ] }, "reaction_10775068": { "compartment": "compartment_7660", "id": "reaction_10775068", "reactome": "R-SCE-3215385", "name": "CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775059" ], "products": [ "species_10775065" ], "modifiers": [ [ "species_10775059", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10778269": { "compartment": "compartment_7660", "id": "reaction_10778269", "reactome": "R-SCE-5649801", "name": "DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_77502", "species_10778245" ], "modifiers": [ [ "species_10778255", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YDR440W" ] }, "reaction_10776189": { "compartment": "compartment_7660", "id": "reaction_10776189", "reactome": "R-SCE-3777129", "name": "HDAC3 containing complexes deacetylate histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10776109" ], "products": [ "species_5566518", "species_10776115" ], "modifiers": [ [ "species_10776186", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "CHEBI:57627", "P53096", "YGL194C", "P38262", "YBR103W", "P25357", "YCR033W" ] }, "reaction_10777324": { "compartment": "compartment_7660", "id": "reaction_10777324", "reactome": "R-SCE-5225649", "name": "RBBP7 binds histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_10775913" ], "products": [ "species_10777322" ], "modifiers": [ [ "species_10777305", "inhibitor" ] ], "additional_components": [ "P36012", "YKL049C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P39984", "YEL056W", "Q12363", "YOR230W", "P13712", "YBR195C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P39984", "YEL056W", "Q12363", "YOR230W", "P36012", "YKL049C", "P13712", "YBR195C", "P36012", "YKL049C" ] }, "reaction_10778200": { "compartment": "compartment_7660", "id": "reaction_10778200", "reactome": "R-SCE-5637686", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775017", "species_77087" ], "products": [ "species_77502", "species_10776782" ], "modifiers": [ [ "species_10778197", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P46995", "YJL168C", "P38827", "YHR119W", "P43132", "YLR015W", "P36124", "YKR029C", "Q12529", "YPL165C", "P39706", "YAR003W", "Q12504", "YDR257C", "P38222", "YBR030W", "P38123", "YBR175W" ] }, "reaction_10777042": { "compartment": "compartment_7660", "id": "reaction_10777042", "reactome": "R-SCE-5205798", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763701", "species_77087" ], "products": [ "species_10777039", "species_77502" ], "modifiers": [ [ "species_10775032", "catalyst" ] ], "additional_components": [ "YBR009C", "YBR009C", "YBR034C" ] }, "reaction_10777010": { "compartment": "compartment_7660", "id": "reaction_10777010", "reactome": "R-SCE-5159245", "name": "SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_10775017", "species_77502" ], "modifiers": [ [ "species_10777007", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P46995", "YJL168C", "P38827", "YHR119W", "P43132", "YLR015W", "P36124", "YKR029C", "P39706", "YAR003W", "Q12504", "YDR257C", "P38123", "YBR175W", "P38222", "YBR030W" ] }, "reaction_10777320": { "compartment": "compartment_7660", "id": "reaction_10777320", "reactome": "R-SCE-5225602", "name": "WDR5 binds Me2sR3-replicative histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777305", "species_10776991" ], "products": [ "species_10777318" ], "modifiers": [], "additional_components": [ "P36012", "YKL049C", "YBR175W", "P36012", "YKL049C", "P38123", "YBR175W" ] }, "reaction_10777047": { "compartment": "compartment_7660", "id": "reaction_10777047", "reactome": "R-SCE-5205799", "name": "CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_77502", "species_10775241" ], "modifiers": [ [ "species_10775065", "catalyst" ], [ "species_10777045", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "Q06488", "YLR357W", "P43609", "YFR037C", "P38274", "YBR133C", "P22082", "YOR290C", "P80428", "YJL081C", "P32597", "YIL126W", "P25632", "YCR052W", "Q12406", "YPR034W", "P53628", "YNR023W", "Q05123", "YMR033W", "Q06168", "YLR321C", "P32591", "YJL176C" ] }, "reaction_10778587": { "compartment": "compartment_7660", "id": "reaction_10778587", "reactome": "R-SCE-5661117", "name": "CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10775241" ], "products": [ "species_10778585", "species_77502" ], "modifiers": [ [ "species_10775065", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10776165": { "compartment": "compartment_7660", "id": "reaction_10776165", "reactome": "R-SCE-3769447", "name": "HDAC1:2-containing complex deacetylate histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10776109" ], "products": [ "species_5566518", "species_10776115" ], "modifiers": [ [ "species_10776160", "catalyst" ], [ "species_10776163", "inhibitor" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P09547", "YPL016W", "Q12206", "YOR229W", "Q03010", "YPL139C", "Q03124", "YML127W", "P40505", "YIL084C", "P39984", "YEL056W", "Q12363", "YOR230W", "P13712", "YBR195C", "P31385", "YAL013W", "P38429", "YMR263W", "Q12214", "YPR068C", "LigandDisplayForward?ligandId=7489", "P09547", "YPL016W", "Q03124", "YML127W", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "P39984", "YEL056W", "LigandDisplayForward?ligandId=6852", "P31385", "YAL013W", "LigandDisplayForward?ligandId=7496", "Q12214", "YPR068C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P40505", "YIL084C", "Q12363", "YOR230W", "P13712", "YBR195C", "P38429", "YMR263W" ] }, "reaction_10777211": { "compartment": "compartment_7660", "id": "reaction_10777211", "reactome": "R-SCE-5205867", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777175", "species_77087" ], "products": [ "species_77502", "species_10777209" ], "modifiers": [ [ "species_10775032", "catalyst" ] ], "additional_components": [ "P04912", "YBL003C", "P04911", "YDR225W", "P04912", "YBL003C", "P04911", "YDR225W", "YBR034C" ] }, "reaction_10778258": { "compartment": "compartment_7660", "id": "reaction_10778258", "reactome": "R-SCE-5649764", "name": "DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10778245" ], "products": [ "species_77502", "species_10778250" ], "modifiers": [ [ "species_10778255", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YDR440W" ] }, "reaction_10778598": { "compartment": "compartment_7660", "id": "reaction_10778598", "reactome": "R-SCE-5661126", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777039", "species_77087" ], "products": [ "species_10778596", "species_77502" ], "modifiers": [ [ "species_10775032", "catalyst" ] ], "additional_components": [ "YBR009C", "YBR009C", "YBR034C" ] }, "reaction_10778237": { "compartment": "compartment_7660", "id": "reaction_10778237", "reactome": "R-SCE-5638157", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776742", "species_77087" ], "products": [ "species_10778230", "species_77502" ], "modifiers": [ [ "species_10776872", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P46995", "YJL168C", "Q12529", "YPL165C", "P38890", "YHR207C" ] }, "reaction_10776851": { "compartment": "compartment_7660", "id": "reaction_10776851", "reactome": "R-SCE-4827382", "name": "SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10776759" ], "products": [ "species_10776843", "species_77502" ], "modifiers": [ [ "species_10776848", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YHR119W" ] }, "reaction_10778273": { "compartment": "compartment_7660", "id": "reaction_10778273", "reactome": "R-SCE-5649802", "name": "WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10776818" ], "products": [ "species_10778271", "species_77502" ], "modifiers": [ [ "species_10776856", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YJL168C" ] }, "reaction_10776875": { "compartment": "compartment_7660", "id": "reaction_10776875", "reactome": "R-SCE-4827383", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_10776742", "species_77502" ], "modifiers": [ [ "species_10776872", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P46995", "YJL168C", "Q12529", "YPL165C", "P38890", "YHR207C" ] }, "reaction_10777413": { "compartment": "compartment_7660", "id": "reaction_10777413", "reactome": "R-SCE-5244692", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10776782" ], "products": [ "species_10777406", "species_77502" ], "modifiers": [ [ "species_10777410", "catalyst" ], [ "species_10777134", "inhibitor" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P38827", "YHR119W", "P43132", "YLR015W", "P36124", "YKR029C", "Q12529", "YPL165C", "P39706", "YAR003W", "P38123", "YBR175W", "P36012", "YKL049C" ] }, "reaction_10789077": { "compartment": "compartment_7660", "id": "reaction_10789077", "reactome": "R-SCE-9679787", "name": "HDAC1:2-containing complex binds HDAC2 Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776160", "species_9679795" ], "products": [ "species_10776163" ], "modifiers": [], "additional_components": [ "P09547", "YPL016W", "Q12206", "YOR229W", "Q03010", "YPL139C", "Q03124", "YML127W", "P40505", "YIL084C", "P39984", "YEL056W", "Q12363", "YOR230W", "P13712", "YBR195C", "P31385", "YAL013W", "P38429", "YMR263W", "Q12214", "YPR068C", "LigandDisplayForward?ligandId=7489", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "LigandDisplayForward?ligandId=6852", "LigandDisplayForward?ligandId=7496", "LigandDisplayForward?ligandId=7489", "P09547", "YPL016W", "Q03124", "YML127W", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "P39984", "YEL056W", "LigandDisplayForward?ligandId=6852", "P31385", "YAL013W", "LigandDisplayForward?ligandId=7496", "Q12214", "YPR068C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P40505", "YIL084C", "Q12363", "YOR230W", "P13712", "YBR195C", "P38429", "YMR263W" ] }, "reaction_10778240": { "compartment": "compartment_7660", "id": "reaction_10778240", "reactome": "R-SCE-5638333", "name": "WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_10776823", "species_77502" ], "modifiers": [ [ "species_10776856", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YJL168C" ] }, "reaction_10778267": { "compartment": "compartment_7660", "id": "reaction_10778267", "reactome": "R-SCE-5649800", "name": "WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10776823" ], "products": [ "species_77502", "species_10776818" ], "modifiers": [ [ "species_10776856", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YJL168C" ] }, "reaction_10776286": { "compartment": "compartment_7660", "id": "reaction_10776286", "reactome": "R-SCE-3782655", "name": "HDAC10 deacetylates histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10776109" ], "products": [ "species_5566518", "species_10776115" ], "modifiers": [ [ "species_10776283", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "YNL021W" ] }, "reaction_10778195": { "compartment": "compartment_70101", "id": "reaction_10778195", "reactome": "R-SCE-5634802", "name": "MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778184", "species_71284" ], "products": [ "species_71285", "species_10778188" ], "modifiers": [ [ "species_10778190", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YDR216W" ] }, "reaction_10782722": { "compartment": "compartment_876", "id": "reaction_10782722", "reactome": "R-SCE-6797630", "name": "LRPP4(LRPP1-3,5) hydrolyse LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_417891", "species_109276" ], "products": [ "species_6797635", "species_109277" ], "modifiers": [ [ "species_10782719", "catalyst" ] ], "additional_components": [ "Q05521", "YDR284C", "Q04396", "YDR503C" ] }, "reaction_10769347": { "compartment": "compartment_876", "id": "reaction_10769347", "reactome": "R-SCE-418574", "name": "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769184" ], "products": [ "species_10769344" ], "modifiers": [ [ "species_10769184", "catalyst" ] ], "additional_components": [ "species_29438", "P10823", "YER020W", "species_111349", "P10823", "YER020W", "species_29438", "P10823", "YER020W" ] }, "reaction_10769393": { "compartment": "compartment_70101", "id": "reaction_10769393", "reactome": "R-SCE-419166", "name": "GEFs activate RhoA,B,C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10769303" ], "products": [ "species_10769305", "species_29420" ], "modifiers": [ [ "species_10769390", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_111349", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q05670", "YMR232W", "P04821", "YLR310C", "P34216", "YBL047C", "P07866", "YAL024C", "P25300", "YCR038C" ] }, "reaction_10769338": { "compartment": "compartment_70101", "id": "reaction_10769338", "reactome": "R-SCE-418553", "name": "cAMP degradation by Phosphodiesterases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_29356" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10769330", "catalyst" ] ], "additional_components": [ "YOR360C" ] }, "reaction_10770069": { "compartment": "compartment_70101", "id": "reaction_10770069", "reactome": "R-SCE-429860", "name": "DCP1-DCP2 complex decaps mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770038", "species_29356" ], "products": [ "species_430004", "species_10770040" ], "modifiers": [ [ "species_10770066", "catalyst" ] ], "additional_components": [ "P25644", "YCR077C", "P40070", "YER112W", "P57743", "YLR438C-A", "P53905", "YNL147W", "P40089", "YER146W", "P47017", "YJL124C", "Q06406", "YDR378C", "P38203", "YBL026W", "P25644", "YCR077C", "P40070", "YER112W", "P57743", "YLR438C-A", "P53905", "YNL147W", "P40089", "YER146W", "P47017", "YJL124C", "Q06406", "YDR378C", "P38203", "YBL026W", "P39517", "YDL160C", "P53550", "YNL118C", "P39998", "YEL015W", "Q12517", "YOL149W" ] }, "reaction_10770142": { "compartment": "compartment_70101", "id": "reaction_10770142", "reactome": "R-SCE-430028", "name": "Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429974", "species_29356" ], "products": [ "species_109395", "species_109402", "species_429926", "species_76577", "species_113578" ], "modifiers": [ [ "species_10770139", "catalyst" ] ], "additional_components": [ "Q02793", "SKI8", "P53859", "CSL4", "Q08285", "RRP40", "Q12277", "RRP42", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "P35207", "SKI2", "P53256", "RRP46", "P38792", "RRP4", "P48240", "MTR3", "Q08162", "DIS3", "P17883", "SKI3" ] }, "reaction_10770077": { "compartment": "compartment_70101", "id": "reaction_10770077", "reactome": "R-SCE-429961", "name": "DCPS scavenges the 7-methylguanosine cap of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429926", "species_29356" ], "products": [ "species_429925", "species_430042" ], "modifiers": [ [ "species_10770074", "catalyst" ] ], "additional_components": [ "YLR270W" ] }, "reaction_10770079": { "compartment": "compartment_70101", "id": "reaction_10770079", "reactome": "R-SCE-429978", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429974", "species_10770036" ], "products": [ "species_10770038" ], "modifiers": [], "additional_components": [ "P25644", "YCR077C", "P40070", "YER112W", "P57743", "YLR438C-A", "P53905", "YNL147W", "P40089", "YER146W", "P47017", "YJL124C", "Q06406", "YDR378C", "P38203", "YBL026W", "P25644", "YCR077C", "P40070", "YER112W", "P57743", "YLR438C-A", "P53905", "YNL147W", "P40089", "YER146W", "P47017", "YJL124C", "Q06406", "YDR378C", "P38203", "YBL026W" ] }, "reaction_10771594": { "compartment": "compartment_876", "id": "reaction_10771594", "reactome": "R-SCE-917870", "name": "SLC46A1 transports hemes from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310" ], "products": [ "species_9707308" ], "modifiers": [ [ "species_10767491", "catalyst" ] ], "additional_components": [ "species_189444", "CHEBI:36144", "species_189444", "CHEBI:36144", "YJL163C" ] }, "reaction_10769319": { "compartment": "compartment_876", "id": "reaction_10769319", "reactome": "R-SCE-418309", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016" ], "products": [ "species_74112" ], "modifiers": [ [ "species_10769310", "catalyst" ] ], "additional_components": [ "YGL006W" ] }, "reaction_10777836": { "compartment": "compartment_70101", "id": "reaction_10777836", "reactome": "R-SCE-5578910", "name": "KCNK dimers transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10777833", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10777914": { "compartment": "compartment_876", "id": "reaction_10777914", "reactome": "R-SCE-5617178", "name": "ATP2B4 binds to NOS1, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769316", "species_10769321" ], "products": [ "species_10777912" ], "modifiers": [], "additional_components": [ "YGL006W", "YHR042W", "P16603", "YHR042W", "P38929", "YGL006W" ] }, "reaction_10789363": { "compartment": "compartment_7660", "id": "reaction_10789363", "reactome": "R-SCE-9757256", "name": "MCM3 binds MCM5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760359", "species_10760355" ], "products": [ "species_10760361" ], "modifiers": [], "additional_components": [ "P24279", "MCM3", "P29496", "MCM5" ] }, "reaction_10789309": { "compartment": "compartment_7660", "id": "reaction_10789309", "reactome": "R-SCE-9749197", "name": "ORC1 binds to H4K20me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789305", "species_10760200" ], "products": [ "species_10789307" ], "modifiers": [], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "P54784", "phospho-ORC1", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10789288": { "compartment": "compartment_70101", "id": "reaction_10789288", "reactome": "R-SCE-9734730", "name": "ORC1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789286" ], "products": [ "species_10760200" ], "modifiers": [], "additional_components": [] }, "reaction_10789367": { "compartment": "compartment_7660", "id": "reaction_10789367", "reactome": "R-SCE-9757258", "name": "MCM2 binds MCM4:MCM6:MCM7 heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760349", "species_10760335" ], "products": [ "species_10760351" ], "modifiers": [], "additional_components": [ "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6" ] }, "reaction_10760180": { "compartment": "compartment_7660", "id": "reaction_10760180", "reactome": "R-SCE-68595", "name": "ORC2 binds ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760176", "species_10760172" ], "products": [ "species_10760178" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P54790", "ORC3" ] }, "reaction_10760188": { "compartment": "compartment_7660", "id": "reaction_10760188", "reactome": "R-SCE-68603", "name": "ORC5 binds ORC2:ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760178", "species_10760184" ], "products": [ "species_10760186" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P54790", "ORC3", "P32833", "ORC2", "P50874", "ORC5", "P54790", "ORC3" ] }, "reaction_10760196": { "compartment": "compartment_7660", "id": "reaction_10760196", "reactome": "R-SCE-68610", "name": "Formation of ORC(2-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760192", "species_10760186" ], "products": [ "species_10760194" ], "modifiers": [ [ "species_29358", "catalyst" ] ], "additional_components": [ "P32833", "ORC2", "P50874", "ORC5", "P54790", "ORC3", "P32833", "ORC2", "P54791", "ORC4", "P50874", "ORC5", "P54790", "ORC3" ] }, "reaction_10760222": { "compartment": "compartment_7660", "id": "reaction_10760222", "reactome": "R-SCE-68688", "name": "CDC6 association with ORC(1-6) at replication origins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760214", "species_10760218" ], "products": [ "species_10760220" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P54791", "ORC4", "P54784", "phospho-ORC1", "P50874", "ORC5", "P54790", "ORC3", "P32833", "ORC2", "P54791", "ORC4", "P54784", "phospho-ORC1", "P09119", "CDC6", "P50874", "ORC5", "P54790", "ORC3" ] }, "reaction_10789311": { "compartment": "compartment_7660", "id": "reaction_10789311", "reactome": "R-SCE-9749253", "name": "Formation of MCM2-7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760361", "species_10760351" ], "products": [ "species_10760363" ], "modifiers": [], "additional_components": [ "P24279", "MCM3", "P29496", "MCM5", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29496", "MCM5" ] }, "reaction_10789365": { "compartment": "compartment_7660", "id": "reaction_10789365", "reactome": "R-SCE-9757257", "name": "MCM4, MCM6 and MCM7 form a heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760343", "species_10760347", "species_10760339" ], "products": [ "species_10760349" ], "modifiers": [], "additional_components": [ "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6" ] }, "reaction_10760210": { "compartment": "compartment_7660", "id": "reaction_10760210", "reactome": "R-SCE-68611", "name": "Formation of ORC(1-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760194", "species_10760204" ], "products": [ "species_10760208" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P54791", "ORC4", "P50874", "ORC5", "P54790", "ORC3", "P54784", "phospho-ORC1", "P32833", "ORC2", "P54791", "ORC4", "P54784", "phospho-ORC1", "P50874", "ORC5", "P54790", "ORC3" ] }, "reaction_10784856": { "compartment": "compartment_7660", "id": "reaction_10784856", "reactome": "R-SCE-6810376", "name": "ING2 binds PI5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776424", "species_6810408" ], "products": [ "species_10784854" ], "modifiers": [], "additional_components": [ "Q08465", "YOR064C", "P50947", "YNL097C", "P38806", "YHR090C", "Q08465", "YOR064C", "species_1806240", "P50947", "YNL097C", "P38806", "YHR090C" ] }, "reaction_10786979": { "compartment": "compartment_7660", "id": "reaction_10786979", "reactome": "R-SCE-8877692", "name": "PIN1 binds phosphorylated PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786972", "species_10771753" ], "products": [ "species_10786977" ], "modifiers": [], "additional_components": [ "P38994", "YDR208W", "YJR017C", "P38994", "YDR208W", "P22696", "YJR017C" ] }, "reaction_10786975": { "compartment": "compartment_7660", "id": "reaction_10786975", "reactome": "R-SCE-8877691", "name": "MAP2K6 phosphorylates PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10786961" ], "products": [ "species_113582", "species_10786972" ], "modifiers": [ [ "species_10770703", "catalyst" ] ], "additional_components": [ "P38994", "YDR208W", "P38994", "YDR208W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10764546": { "compartment": "compartment_70101", "id": "reaction_10764546", "reactome": "R-SCE-109702", "name": "PDPK1 phosphorylates AKT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10764531" ], "products": [ "species_29370", "species_10764543" ], "modifiers": [ [ "species_10764515", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10764517": { "compartment": "compartment_876", "id": "reaction_10764517", "reactome": "R-SCE-109701", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10764513" ], "products": [ "species_10764515" ], "modifiers": [], "additional_components": [ "YOL100W", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10772818": { "compartment": "compartment_70101", "id": "reaction_10772818", "reactome": "R-SCE-1358791", "name": "Phosphorylation of USP8 by P-AKT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772805", "species_113592" ], "products": [ "species_29370", "species_10772816" ], "modifiers": [ [ "species_10767105", "catalyst" ] ], "additional_components": [ "P39538", "YJL197W", "P32571", "YDR069C", "P39944", "YER144C", "P39538", "YJL197W", "P32571", "YDR069C", "P39944", "YER144C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10768224": { "compartment": "compartment_984", "id": "reaction_10768224", "reactome": "R-SCE-265456", "name": "NPC1L1 binds ezetimibe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265479", "species_10768220" ], "products": [ "species_10768222" ], "modifiers": [], "additional_components": [ "YPL006W", "species_265479", "Q12200", "YPL006W" ] }, "reaction_10777748": { "compartment": "compartment_70101", "id": "reaction_10777748", "reactome": "R-SCE-5362564", "name": "ADH1A,1C,4 oxidise atROL to atRAL in vitro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_73473", "species_975622" ], "modifiers": [ [ "species_10777745", "catalyst" ] ], "additional_components": [ "species_158417", "P32771", "YDL168W" ] }, "reaction_10777718": { "compartment": "compartment_70101", "id": "reaction_10777718", "reactome": "R-SCE-5362518", "name": "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_73473", "species_975622" ], "modifiers": [ [ "species_10777715", "catalyst" ] ], "additional_components": [ "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C" ] }, "reaction_10777743": { "compartment": "compartment_70101", "id": "reaction_10777743", "reactome": "R-SCE-5362522", "name": "ALDHs oxidise atRAL to atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975622", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_5334816" ], "modifiers": [ [ "species_10777740", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10777778": { "compartment": "compartment_70101", "id": "reaction_10777778", "reactome": "R-SCE-5419165", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_975622" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10777775", "catalyst" ] ], "additional_components": [ "P34251", "YNL181W", "Q08651", "YOR246C", "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C", "P53878", "YNL181W" ] }, "reaction_10784158": { "compartment": "compartment_7660", "id": "reaction_10784158", "reactome": "R-SCE-6802973", "name": "PLK3 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10763791" ], "products": [ "species_113582", "species_10784153" ], "modifiers": [ [ "species_10784155", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "YMR001C" ] }, "reaction_10766925": { "compartment": "compartment_876", "id": "reaction_10766925", "reactome": "R-SCE-196017", "name": "Dynamin is recruited to the gap junction plaque", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766678", "species_10766651" ], "products": [ "species_10766680" ], "modifiers": [], "additional_components": [ "P54861", "YLL001W", "P21576", "YKR001C", "P32266", "YOR211C", "P60010", "YFL039C", "P17891", "YGR167W", "Q99186", "YOL062C", "P22137", "YGL206C", "P60010", "YFL039C", "P54861", "YLL001W", "P17891", "YGR167W", "P21576", "YKR001C", "P32266", "YOR211C", "Q99186", "YOL062C", "P22137", "YGL206C" ] }, "reaction_10788439": { "compartment": "compartment_17947", "id": "reaction_10788439", "reactome": "R-SCE-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788429" ], "products": [ "species_10787654", "species_10788437" ], "modifiers": [], "additional_components": [ "P15202", "YDR256C", "P32573", "YNL202W", "P53112", "PEX14", "P32796", "YML042W", "P21954", "YDL066W", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P13711", "YGL205W", "Q12524", "YLR151C", "Q02207", "YKR009C", "P80667", "PEX13", "P16603", "YHR042W", "Q04370", "YMR026C", "Q06010", "YLR389C", "P31787", "YGR037C", "P39994", "YEL020C", "P00175", "CYB2", "P41903", "YJR019C", "P35056", "phospho-PEX5", "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "Q05568", "YDR265W", "P15202", "YDR256C", "P32573", "YNL202W", "P13711", "YGL205W", "Q12524", "YLR151C", "Q02207", "YKR009C", "P32796", "YML042W", "P21954", "YDL066W", "P16603", "YHR042W", "Q06010", "YLR389C", "P31787", "YGR037C", "P39994", "YEL020C", "P00175", "CYB2", "P41903", "YJR019C" ] }, "reaction_10788389": { "compartment": "compartment_70101", "id": "reaction_10788389", "reactome": "R-SCE-9033232", "name": "PEX7 binds cargo proteins containing PTS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788385", "species_10788379" ], "products": [ "species_10788387" ], "modifiers": [], "additional_components": [ "P47181", "YJR154W", "P27796", "YIL160C", "YDR142C", "P47181", "YJR154W", "P39108", "YDR142C", "P27796", "YIL160C" ] }, "reaction_10788486": { "compartment": "compartment_17947", "id": "reaction_10788486", "reactome": "R-SCE-9033527", "name": "PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788445", "species_10787658" ], "products": [ "species_10788447" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W" ] }, "reaction_10788441": { "compartment": "compartment_17947", "id": "reaction_10788441", "reactome": "R-SCE-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788427", "species_10788425" ], "products": [ "species_10788429" ], "modifiers": [], "additional_components": [ "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "Q05568", "YDR265W", "P15202", "YDR256C", "P32573", "YNL202W", "P32796", "YML042W", "P21954", "YDL066W", "P35056", "phospho-PEX5", "P13711", "YGL205W", "Q12524", "YLR151C", "Q02207", "YKR009C", "P16603", "YHR042W", "Q06010", "YLR389C", "P31787", "YGR037C", "P39994", "YEL020C", "P00175", "CYB2", "P41903", "YJR019C", "P15202", "YDR256C", "P32573", "YNL202W", "P53112", "PEX14", "P32796", "YML042W", "P21954", "YDL066W", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P13711", "YGL205W", "Q12524", "YLR151C", "Q02207", "YKR009C", "P80667", "PEX13", "P16603", "YHR042W", "Q04370", "YMR026C", "Q06010", "YLR389C", "P31787", "YGR037C", "P39994", "YEL020C", "P00175", "CYB2", "P41903", "YJR019C" ] }, "reaction_10788484": { "compartment": "compartment_17947", "id": "reaction_10788484", "reactome": "R-SCE-9033514", "name": "Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788476" ], "products": [ "species_10788445", "species_10788482" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P47181", "YJR154W", "P80667", "PEX13", "Q04370", "YMR026C", "P39108", "YDR142C", "P27796", "YIL160C", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W", "P47181", "YJR154W", "P27796", "YIL160C" ] }, "reaction_10788452": { "compartment": "compartment_17947", "id": "reaction_10788452", "reactome": "R-SCE-9033485", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788447" ], "products": [ "species_10772640", "species_10788449" ], "modifiers": [ [ "species_10788447", "catalyst" ] ], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W", "P15731", "YBR082C", "P15732", "YDR059C", "P35056", "phospho-PEX5", "P53112", "PEX14", "P05759", "RPS31", "P80667", "PEX13", "Q04370", "YMR026C", "P39108", "YDR142C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W" ] }, "reaction_10766513": { "compartment": "compartment_876", "id": "reaction_10766513", "reactome": "R-SCE-189242", "name": "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189246" ], "products": [ "species_189219" ], "modifiers": [ [ "species_10766510", "catalyst" ] ], "additional_components": [ "species_70113", "species_29532", "CHEBI:17118", "species_70113", "species_29532", "CHEBI:17118", "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10766502": { "compartment": "compartment_876", "id": "reaction_10766502", "reactome": "R-SCE-189222", "name": "SLC2A5 transports fructose from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189049" ], "products": [ "species_29532" ], "modifiers": [ [ "species_10766499", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10782658": { "compartment": "compartment_70101", "id": "reaction_10782658", "reactome": "R-SCE-6795290", "name": "TORC2 complex phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782648", "species_113592" ], "products": [ "species_29370", "species_10782656" ], "modifiers": [ [ "species_10767216", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "P11792", "YHR205W", "Q08236", "YOL078W", "P32600", "YKL203C", "P41318", "YNL006W", "P40061", "YER093C", "P38346", "YBR270C", "P47041", "YJL058C" ] }, "reaction_10782713": { "compartment": "compartment_7660", "id": "reaction_10782713", "reactome": "R-SCE-6797616", "name": "CCNK:CDK12 binds RNA Pol II at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782693", "species_10782677" ], "products": [ "species_10782695" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3", "Q03957", "YKL139W", "Q05949", "YLR226W", "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3" ] }, "reaction_10784265": { "compartment": "compartment_7660", "id": "reaction_10784265", "reactome": "R-SCE-6805640", "name": "AKT phosphorylates KAT6A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10775476" ], "products": [ "species_113582", "species_10784263" ], "modifiers": [ [ "species_10767347", "catalyst" ] ], "additional_components": [ "Q12311", "YPR031W", "Q08465", "YOR064C", "Q08649", "YOR244W", "P50947", "YNL097C", "P38806", "YHR090C", "P47128", "YJR082C", "Q12311", "YPR031W", "Q08649", "YOR244W", "Q08465", "YOR064C", "P50947", "YNL097C", "P38806", "YHR090C", "P47128", "YJR082C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10767160": { "compartment": "compartment_70101", "id": "reaction_10767160", "reactome": "R-SCE-198599", "name": "AKT phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10767147" ], "products": [ "species_29370", "species_10767157" ], "modifiers": [ [ "species_10767105", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10782671": { "compartment": "compartment_70101", "id": "reaction_10782671", "reactome": "R-SCE-6795473", "name": "PDPK1 phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10782656" ], "products": [ "species_29370", "species_10782666" ], "modifiers": [ [ "species_10764515", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "P11792", "YHR205W", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10784830": { "compartment": "compartment_7660", "id": "reaction_10784830", "reactome": "R-SCE-6810233", "name": "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784818", "species_29358" ], "products": [ "species_113582", "species_10784827" ], "modifiers": [ [ "species_10784818", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P53968", "YNL027W", "P04050", "YDL140C", "P32774", "YKL058W", "P13393", "SPT15", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P53968", "YNL027W", "P04050", "YDL140C", "P32774", "YKL058W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P53968", "YNL027W", "P04050", "YDL140C", "P32774", "YKL058W", "P13393", "SPT15", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C" ] }, "reaction_10784216": { "compartment": "compartment_7660", "id": "reaction_10784216", "reactome": "R-SCE-6804942", "name": "MDM2 homodimers auto-ubiquitinate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760537", "species_10784206" ], "products": [ "species_10784213" ], "modifiers": [ [ "species_10784206", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W" ] }, "reaction_10782642": { "compartment": "compartment_70101", "id": "reaction_10782642", "reactome": "R-SCE-6793666", "name": "MDM2 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767157" ], "products": [ "species_10768288" ], "modifiers": [], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W" ] }, "reaction_10782679": { "compartment": "compartment_7660", "id": "reaction_10782679", "reactome": "R-SCE-6797090", "name": "CCNK binds CDK12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782675", "species_10765011" ], "products": [ "species_10782677" ], "modifiers": [], "additional_components": [ "YKL139W", "YLR226W", "Q03957", "YKL139W", "Q05949", "YLR226W" ] }, "reaction_10784852": { "compartment": "compartment_7660", "id": "reaction_10784852", "reactome": "R-SCE-6810235", "name": "RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784835", "species_10784846", "species_10784844", "species_10784827" ], "products": [ "species_10784850" ], "modifiers": [], "additional_components": [ "YER139C", "YDR289C", "Q05543", "YDR289C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P53968", "YNL027W", "P04050", "YDL140C", "P32774", "YKL058W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P40084", "YER139C", "P53968", "YNL027W", "P04050", "YDL140C", "Q05543", "YDR289C", "P32774", "YKL058W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C" ] }, "reaction_10765625": { "compartment": "compartment_5460", "id": "reaction_10765625", "reactome": "R-SCE-163310", "name": "TFAM binds to mitochondrial promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163305", "species_10765621" ], "products": [ "species_10765623" ], "modifiers": [], "additional_components": [ "Q03435", "YDL002C", "Q02486", "YMR072W", "P33417", "YKL032C", "Q03973", "YDR174W", "P11633", "YBR089C-A", "Q03435", "YDL002C", "Q02486", "YMR072W", "P33417", "YKL032C", "Q03973", "YDR174W", "P11633", "YBR089C-A" ] }, "reaction_10782685": { "compartment": "compartment_7660", "id": "reaction_10782685", "reactome": "R-SCE-6797100", "name": "CCNK binds CDK13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782681", "species_10765011" ], "products": [ "species_10782683" ], "modifiers": [], "additional_components": [ "YKL139W", "YLR226W", "Q03957", "YKL139W", "Q05949", "YLR226W" ] }, "reaction_10782673": { "compartment": "compartment_70101", "id": "reaction_10782673", "reactome": "R-SCE-6795667", "name": "MDM2 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774893" ], "products": [ "species_10767147" ], "modifiers": [], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W" ] }, "reaction_10782640": { "compartment": "compartment_7660", "id": "reaction_10782640", "reactome": "R-SCE-6793661", "name": "(CDK1,CDK2):CCNA phosphorylates MDM2 at T218", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10768288" ], "products": [ "species_113582", "species_10782638" ], "modifiers": [ [ "species_10760454", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10782669": { "compartment": "compartment_70101", "id": "reaction_10782669", "reactome": "R-SCE-6795460", "name": "SGK1 phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10767147" ], "products": [ "species_29370", "species_10767157" ], "modifiers": [ [ "species_10782666", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10784258": { "compartment": "compartment_7660", "id": "reaction_10784258", "reactome": "R-SCE-6805061", "name": "CK2 binds FACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765099", "species_10784254" ], "products": [ "species_10784256" ], "modifiers": [], "additional_components": [ "P32558", "YGL207W", "Q04636", "YML069W", "P15790", "CKA1", "P38930", "CKB2", "P19454", "CKA2", "P15790", "CKA1", "P38930", "CKB2", "P32558", "YGL207W", "Q04636", "YML069W", "P19454", "CKA2" ] }, "reaction_10782711": { "compartment": "compartment_7660", "id": "reaction_10782711", "reactome": "R-SCE-6797606", "name": "CDK12 phosphorylates RNA Pol II CTD at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782695", "species_29358" ], "products": [ "species_113582", "species_10782708" ], "modifiers": [ [ "species_10782695", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3" ] }, "reaction_10770856": { "compartment": "compartment_7660", "id": "reaction_10770856", "reactome": "R-SCE-450550", "name": "PKCalpha phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770833", "species_29358" ], "products": [ "species_113582", "species_10770851" ], "modifiers": [ [ "species_10770853", "catalyst" ] ], "additional_components": [ "YDR429C", "YDR429C", "YBL105C" ] }, "reaction_10770848": { "compartment": "compartment_7660", "id": "reaction_10770848", "reactome": "R-SCE-450533", "name": "PKCdelta phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770833", "species_29358" ], "products": [ "species_113582", "species_10770843" ], "modifiers": [ [ "species_10770845", "catalyst" ] ], "additional_components": [ "YDR429C", "YDR429C", "YBL105C" ] }, "reaction_10771129": { "compartment": "compartment_7660", "id": "reaction_10771129", "reactome": "R-SCE-517705", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770843", "species_517622" ], "products": [ "species_10771127" ], "modifiers": [], "additional_components": [ "YDR429C", "Q04067", "YDR429C" ] }, "reaction_10771125": { "compartment": "compartment_7660", "id": "reaction_10771125", "reactome": "R-SCE-517674", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450605", "species_10770851" ], "products": [ "species_10771123" ], "modifiers": [], "additional_components": [ "YDR429C", "Q04067", "YDR429C" ] }, "reaction_10770837": { "compartment": "compartment_7660", "id": "reaction_10770837", "reactome": "R-SCE-450494", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770833", "species_450613" ], "products": [ "species_10770835" ], "modifiers": [], "additional_components": [ "YDR429C", "Q04067", "YDR429C" ] }, "reaction_10776322": { "compartment": "compartment_7660", "id": "reaction_10776322", "reactome": "R-SCE-3878123", "name": "Initiation of SAHF formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776313", "species_10776308", "species_10776318", "species_10776303" ], "products": [ "species_10776320" ], "modifiers": [], "additional_components": [ "YBR215W", "YBL008W", "YJR140C", "YJL115W", "Q01448", "YBR215W", "P32479", "YBL008W", "P32447", "YJL115W", "P47171", "YJR140C" ] }, "reaction_10771087": { "compartment": "compartment_876", "id": "reaction_10771087", "reactome": "R-SCE-507868", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10771084", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771099": { "compartment": "compartment_876", "id": "reaction_10771099", "reactome": "R-SCE-507873", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29514" ], "products": [ "species_432019" ], "modifiers": [ [ "species_10771096", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10770170": { "compartment": "compartment_876", "id": "reaction_10770170", "reactome": "R-SCE-432074", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10770167", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771101": { "compartment": "compartment_876", "id": "reaction_10771101", "reactome": "R-SCE-507875", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10771096", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771094": { "compartment": "compartment_876", "id": "reaction_10771094", "reactome": "R-SCE-507871", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10771084", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10770159": { "compartment": "compartment_876", "id": "reaction_10770159", "reactome": "R-SCE-432049", "name": "Aquaporin-9 passively transports glycerol into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10770156", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771092": { "compartment": "compartment_876", "id": "reaction_10771092", "reactome": "R-SCE-507870", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10771084", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771090": { "compartment": "compartment_876", "id": "reaction_10771090", "reactome": "R-SCE-507869", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10771084", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10772773": { "compartment": "compartment_876", "id": "reaction_10772773", "reactome": "R-SCE-1299338", "name": "Activation of TRESK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772770", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10772786": { "compartment": "compartment_876", "id": "reaction_10772786", "reactome": "R-SCE-1299359", "name": "Activation of TALK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772783", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10772753": { "compartment": "compartment_876", "id": "reaction_10772753", "reactome": "R-SCE-1299304", "name": "Activation of tandem pore domain in a weak inwardly rectifying K+ channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772750", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10772736": { "compartment": "compartment_876", "id": "reaction_10772736", "reactome": "R-SCE-1299297", "name": "Activation of THIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772733", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10787432": { "compartment": "compartment_13231", "id": "reaction_10787432", "reactome": "R-SCE-8944457", "name": "MAF1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787425" ], "products": [ "species_10787423" ], "modifiers": [], "additional_components": [ "YDR005C", "YDR005C" ] }, "reaction_10764398": { "compartment": "compartment_7660", "id": "reaction_10764398", "reactome": "R-SCE-77589", "name": "Recognition of AAUAAA sequence by CPSF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762363", "species_10764394" ], "products": [ "species_10764396" ], "modifiers": [], "additional_components": [ "Q01329", "YAL043C", "Q12102", "YLR115W", "P45976", "YJR093C", "P42841", "YNL317W", "Q06224", "YLR277C", "Q06102", "YPR107C", "Q06632", "YDR301W", "P34160", "YMR125W", "Q08920", "YPL178W", "P34160", "YMR125W", "Q01329", "YAL043C", "Q12102", "YLR115W", "P45976", "YJR093C", "P42841", "YNL317W", "Q06224", "YLR277C", "Q08920", "YPL178W", "Q06102", "YPR107C", "Q06632", "YDR301W" ] }, "reaction_10789005": { "compartment": "compartment_70101", "id": "reaction_10789005", "reactome": "R-SCE-9664883", "name": "ATM:PEX5 translocates from cytosol to peroxisomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788984" ], "products": [ "species_10788990" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P38110", "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10788897": { "compartment": "compartment_70101", "id": "reaction_10788897", "reactome": "R-SCE-9646348", "name": "PolyUb-Misfolded Proteins:HDAC6 bind dynein motor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788876", "species_10788893" ], "products": [ "species_10788895" ], "modifiers": [], "additional_components": [ "P05759", "RPS31", "P53973", "YNL021W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P0CE68", "YKR103W", "P12866", "YKL209C", "Q02647", "YDR424C", "P40960", "YDR488C", "P36022", "YKR054C", "P05759", "RPS31", "Q02647", "YDR424C", "P53973", "YNL021W", "P40960", "YDR488C", "P36022", "YKR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10788915": { "compartment": "compartment_18667", "id": "reaction_10788915", "reactome": "R-SCE-9646685", "name": "Aggresome dissociates from dynein and microtubule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788907" ], "products": [ "species_10768744", "species_10788913", "species_10788893" ], "modifiers": [], "additional_components": [ "P02557", "YFL037W", "P40960", "YDR488C", "P36022", "YKR054C", "species_29438", "P0CE68", "YKR103W", "species_29420", "P09734", "YML124C", "P05759", "RPS31", "P09733", "YML085C", "Q02647", "YDR424C", "P53973", "YNL021W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P12866", "YKL209C", "species_29420", "P09734", "YML124C", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "P05759", "RPS31", "P53973", "YNL021W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P0CE68", "YKR103W", "P12866", "YKL209C", "Q02647", "YDR424C", "P40960", "YDR488C", "P36022", "YKR054C" ] }, "reaction_10789014": { "compartment": "compartment_17947", "id": "reaction_10789014", "reactome": "R-SCE-9664888", "name": "ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788999" ], "products": [ "species_10789012" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P38110", "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10788869": { "compartment": "compartment_70101", "id": "reaction_10788869", "reactome": "R-SCE-9641127", "name": "Ub:misfolded proteins polymerize to PolyUb:misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788867" ], "products": [ "species_10788867" ], "modifiers": [], "additional_components": [ "P05759", "RPS31", "P53152", "MMS2", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52490", "UBC13", "P0CE68", "YKR103W", "P12866", "YKL209C", "P05759", "RPS31", "P53152", "MMS2", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52490", "UBC13", "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10789001": { "compartment": "compartment_17947", "id": "reaction_10789001", "reactome": "R-SCE-9664862", "name": "ATM dimer:PEX5 phosphorylates PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788992" ], "products": [ "species_10788999" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P38110", "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10788986": { "compartment": "compartment_70101", "id": "reaction_10788986", "reactome": "R-SCE-9664850", "name": "ATM binds PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788982", "species_10788423" ], "products": [ "species_10788984" ], "modifiers": [], "additional_components": [ "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10789003": { "compartment": "compartment_17947", "id": "reaction_10789003", "reactome": "R-SCE-9664879", "name": "ATM:PEX5 binds ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788990", "species_10788988" ], "products": [ "species_10788992" ], "modifiers": [ [ "species_1250243", "catalyst" ] ], "additional_components": [ "P35056", "phospho-PEX5", "P38110", "YBL088C", "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10763693": { "compartment": "compartment_17940", "id": "reaction_10763693", "reactome": "R-SCE-74723", "name": "Endosome acidification", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_74722" ], "modifiers": [ [ "species_10763690", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "P23968", "YHR026W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10779165": { "compartment": "compartment_7660", "id": "reaction_10779165", "reactome": "R-SCE-5682026", "name": "MRN bound to shortened telomeres activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779160" ], "products": [ "species_113582", "species_10779162", "species_10768327" ], "modifiers": [ [ "species_10779160", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10787738": { "compartment": "compartment_7660", "id": "reaction_10787738", "reactome": "R-SCE-8979071", "name": "KDM6B binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111793", "species_10775179" ], "products": [ "species_10775181" ], "modifiers": [], "additional_components": [ "YBR112C", "P14922", "YBR112C", "species_111793" ] }, "reaction_10775231": { "compartment": "compartment_7660", "id": "reaction_10775231", "reactome": "R-SCE-3239019", "name": "Active p38 MAPK phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10775221" ], "products": [ "species_113582", "species_10775228" ], "modifiers": [ [ "species_10775221", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W" ] }, "reaction_10775223": { "compartment": "compartment_7660", "id": "reaction_10775223", "reactome": "R-SCE-3238999", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10775219" ], "products": [ "species_113582", "species_10775221" ], "modifiers": [ [ "species_10770705", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10782617": { "compartment": "compartment_7660", "id": "reaction_10782617", "reactome": "R-SCE-6792712", "name": "KAT5 acetylates ATM at shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782614", "species_113560" ], "products": [ "species_2485002", "species_10779160" ], "modifiers": [ [ "species_10782614", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10775192": { "compartment": "compartment_70101", "id": "reaction_10775192", "reactome": "R-SCE-3228469", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770760", "species_113592" ], "products": [ "species_29370", "species_10770683" ], "modifiers": [ [ "species_10775189", "catalyst" ] ], "additional_components": [ "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C", "YLR362W" ] }, "reaction_10775184": { "compartment": "compartment_7660", "id": "reaction_10775184", "reactome": "R-SCE-3222593", "name": "KDM6B demethylates H3K27me3 on p16INK4A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775172", "species_113671" ], "products": [ "species_10775174", "species_159939" ], "modifiers": [ [ "species_10775181", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P14922", "YBR112C", "species_111793" ] }, "reaction_10771963": { "compartment": "compartment_70101", "id": "reaction_10771963", "reactome": "R-SCE-947591", "name": "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_947588", "species_29356" ], "products": [ "species_29370", "species_947594", "species_29372" ], "modifiers": [ [ "species_10771935", "catalyst" ] ], "additional_components": [ "species_33625", "species_1500581", "species_33625", "species_1500581", "P32660", "YER166W", "P39524", "YAL026C", "P40527", "YIL048W", "Q12675", "YDR093W", "Q12674", "YMR162C" ] }, "reaction_10777455": { "compartment": "compartment_70101", "id": "reaction_10777455", "reactome": "R-SCE-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_5252122" ], "products": [ "species_29370", "species_5252016", "species_29372" ], "modifiers": [ [ "species_10777450", "catalyst" ] ], "additional_components": [ "YOR291W" ] }, "reaction_10775325": { "compartment": "compartment_70101", "id": "reaction_10775325", "reactome": "R-SCE-3295579", "name": "TRPs transport extracellular Ca2+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10775312", "catalyst" ] ], "additional_components": [ "YOR087W" ] }, "reaction_10781096": { "compartment": "compartment_70101", "id": "reaction_10781096", "reactome": "R-SCE-5692462", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29418", "species_29356" ], "products": [ "species_29370", "species_29372", "species_1981162" ], "modifiers": [ [ "species_10781093", "catalyst" ] ], "additional_components": [ "YEL031W" ] }, "reaction_10771860": { "compartment": "compartment_20699", "id": "reaction_10771860", "reactome": "R-SCE-936883", "name": "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_113592", "species_29356" ], "products": [ "species_29370", "species_167012", "species_29372" ], "modifiers": [ [ "species_10771857", "catalyst" ] ], "additional_components": [ "species_109496", "P13586", "YGL167C" ] }, "reaction_10771868": { "compartment": "compartment_20699", "id": "reaction_10771868", "reactome": "R-SCE-936895", "name": "ATP7B transports cytosolic Cu2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_209799" ], "products": [ "species_29370", "species_936901", "species_29372" ], "modifiers": [ [ "species_10771865", "catalyst" ] ], "additional_components": [ "YDR270W" ] }, "reaction_10781101": { "compartment": "compartment_70101", "id": "reaction_10781101", "reactome": "R-SCE-5692480", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_5692450" ], "products": [ "species_29370", "species_29372", "species_5692484" ], "modifiers": [ [ "species_10781098", "catalyst" ] ], "additional_components": [ "YOR291W" ] }, "reaction_10774664": { "compartment": "compartment_70101", "id": "reaction_10774664", "reactome": "R-SCE-2684901", "name": "ANOs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10774659", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "YBR086C" ] }, "reaction_10789201": { "compartment": "compartment_70101", "id": "reaction_10789201", "reactome": "R-SCE-9701141", "name": "TRPV1 transports Ca2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10775312", "catalyst" ] ], "additional_components": [ "YOR087W" ] }, "reaction_10774674": { "compartment": "compartment_70101", "id": "reaction_10774674", "reactome": "R-SCE-2730692", "name": "CLCN4/5/6 exchange Cl- for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_2731008" ], "products": [ "species_352022", "species_74722" ], "modifiers": [ [ "species_10774669", "catalyst" ] ], "additional_components": [ "YJR040W" ] }, "reaction_10768792": { "compartment": "compartment_12045", "id": "reaction_10768792", "reactome": "R-SCE-381091", "name": "IRE1 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768784", "species_113592" ], "products": [ "species_29370", "species_10768789" ], "modifiers": [ [ "species_10768784", "catalyst" ] ], "additional_components": [ "P32361", "phospho-IRE1", "P32361", "phospho-IRE1", "P32361", "phospho-IRE1" ] }, "reaction_10768794": { "compartment": "compartment_12045", "id": "reaction_10768794", "reactome": "R-SCE-381109", "name": "IRE1 binds IRE1 forming dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768782" ], "products": [ "species_10768784" ], "modifiers": [], "additional_components": [ "P32361", "phospho-IRE1" ] }, "reaction_10770262": { "compartment": "compartment_12045", "id": "reaction_10770262", "reactome": "R-SCE-442393", "name": "ZIP7 mediates zinc efflux from the endoplasmic reticulum", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_442320" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10770259", "catalyst" ] ], "additional_components": [ "YIL023C" ] }, "reaction_10779105": { "compartment": "compartment_70101", "id": "reaction_10779105", "reactome": "R-SCE-5679206", "name": "MTMR14, MTMR3 dephosphorylate PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030" ], "products": [ "species_426639" ], "modifiers": [ [ "species_10773546", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10778999": { "compartment": "compartment_70101", "id": "reaction_10778999", "reactome": "R-SCE-5675868", "name": "ULK1 phosphorylates ATG13 and RB1CC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778709", "species_113592" ], "products": [ "species_29370", "species_10778996" ], "modifiers": [ [ "species_10778709", "catalyst" ] ], "additional_components": [ "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779119": { "compartment": "compartment_70101", "id": "reaction_10779119", "reactome": "R-SCE-5681980", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779063", "species_10779115" ], "products": [ "species_10779117" ], "modifiers": [], "additional_components": [ "YBR217W", "P38862", "YHR171W", "P38316", "YBR217W", "P38862", "YHR171W" ] }, "reaction_10778714": { "compartment": "compartment_70101", "id": "reaction_10778714", "reactome": "R-SCE-5672011", "name": "p-AMPK:AMP binds the ULK complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778630", "species_10768748" ], "products": [ "species_10778632" ], "modifiers": [], "additional_components": [ "P53104", "YGL180W", "Q06628", "YPR185W", "Q12527", "YPR049C", "P36002", "YKL198C", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "P36002", "YKL198C", "P34164", "YGL208W", "P53104", "YGL180W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "Q06628", "YPR185W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10788354": { "compartment": "compartment_70101", "id": "reaction_10788354", "reactome": "R-SCE-9020616", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779117" ], "products": [ "species_10779327" ], "modifiers": [], "additional_components": [ "P38316", "YBR217W", "P38862", "YHR171W", "P38316", "YBR217W", "P38862", "YHR171W" ] }, "reaction_10779133": { "compartment": "compartment_70101", "id": "reaction_10779133", "reactome": "R-SCE-5681981", "name": "ATG3 transfers LC3 from ATG7 to ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779128" ], "products": [ "species_10779130" ], "modifiers": [ [ "species_10779128", "catalyst" ] ], "additional_components": [ "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C", "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C", "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C" ] }, "reaction_10778727": { "compartment": "compartment_12045", "id": "reaction_10778727", "reactome": "R-SCE-5672012", "name": "Beclin-1 complex phosphorylates PtdIns", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_5676030", "species_29370" ], "modifiers": [ [ "species_10778724", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W" ] }, "reaction_10778646": { "compartment": "compartment_70101", "id": "reaction_10778646", "reactome": "R-SCE-5665868", "name": "AMPK (complex) phosphorylates ULK1 (complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778632", "species_113592" ], "products": [ "species_29370", "species_10778643" ], "modifiers": [ [ "species_10778632", "catalyst" ] ], "additional_components": [ "P36002", "YKL198C", "P34164", "YGL208W", "P53104", "YGL180W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "Q06628", "YPR185W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P34164", "YGL208W", "P53104", "YGL180W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "Q06628", "YPR185W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779026": { "compartment": "compartment_70101", "id": "reaction_10779026", "reactome": "R-SCE-5676229", "name": "WIPIs bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779022", "species_5693050" ], "products": [ "species_10779024" ], "modifiers": [], "additional_components": [ "Q02887", "YPL100W", "P43601", "YFR021W", "P50079", "YGR223C", "Q02887", "YPL100W", "P43601", "YFR021W", "species_1629751", "P50079", "YGR223C" ] }, "reaction_10778712": { "compartment": "compartment_70101", "id": "reaction_10778712", "reactome": "R-SCE-5672008", "name": "Thr-180 of ULK1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778643", "species_113592" ], "products": [ "species_29370", "species_10778709" ], "modifiers": [ [ "species_10778643", "catalyst" ] ], "additional_components": [ "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779077": { "compartment": "compartment_70101", "id": "reaction_10779077", "reactome": "R-SCE-5678490", "name": "ATG16L1 complex transfers LC3 from ATG3 to PE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5681998", "species_10779055" ], "products": [ "species_10779059", "species_10779057" ], "modifiers": [ [ "species_10779074", "catalyst" ] ], "additional_components": [ "P40344", "YNR007C", "P38182", "YBL078C", "YNR007C", "species_1500581", "P38182", "YBL078C", "species_6809774", "Q12380", "YPL149W", "P43601", "YFR021W", "P38316", "YBR217W" ] }, "reaction_10779143": { "compartment": "compartment_70101", "id": "reaction_10779143", "reactome": "R-SCE-5682011", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779041", "species_10779115" ], "products": [ "species_10779126" ], "modifiers": [], "additional_components": [ "YBL078C", "P38862", "YHR171W", "P38862", "YHR171W", "P38182", "YBL078C" ] }, "reaction_10779211": { "compartment": "compartment_5683628", "id": "reaction_10779211", "reactome": "R-SCE-5682388", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779057" ], "products": [ "species_10779202" ], "modifiers": [ [ "species_10779209", "catalyst" ], [ "species_10771366", "catalyst" ] ], "additional_components": [ "species_1500581", "P38182", "YBL078C", "species_1500581", "P38182", "YBL078C", "Q05919", "YLR360W", "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "Q04272", "YMR077C" ] }, "reaction_10779191": { "compartment": "compartment_12045", "id": "reaction_10779191", "reactome": "R-SCE-5682385", "name": "The phagophore extends from the PIP3-enriched structure", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778724" ], "products": [ "species_10779182" ], "modifiers": [ [ "species_10779187", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "YDL149W" ] }, "reaction_10779329": { "compartment": "compartment_70101", "id": "reaction_10779329", "reactome": "R-SCE-5682896", "name": "LC3:ATG7 dimer binds ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779059", "species_10779126" ], "products": [ "species_10779128" ], "modifiers": [], "additional_components": [ "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C", "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C" ] }, "reaction_10779107": { "compartment": "compartment_70101", "id": "reaction_10779107", "reactome": "R-SCE-5679239", "name": "ULK complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778996" ], "products": [ "species_10779099" ], "modifiers": [], "additional_components": [ "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779420": { "compartment": "compartment_70101", "id": "reaction_10779420", "reactome": "R-SCE-5683925", "name": "ULK1 is dephosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779418" ], "products": [ "species_10778630", "species_29372" ], "modifiers": [], "additional_components": [ "P53104", "YGL180W", "Q06628", "YPR185W", "Q12527", "YPR049C", "P53104", "YGL180W", "Q06628", "YPR185W", "Q12527", "YPR049C" ] }, "reaction_10779102": { "compartment": "compartment_70101", "id": "reaction_10779102", "reactome": "R-SCE-5679205", "name": "ULK1 phosphorylates Beclin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779087", "species_113592" ], "products": [ "species_29370", "species_10778724" ], "modifiers": [ [ "species_10779099", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779387": { "compartment": "compartment_70101", "id": "reaction_10779387", "reactome": "R-SCE-5683593", "name": "ATG7:ATG3:LC3 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779130" ], "products": [ "species_10779115", "species_10779055" ], "modifiers": [], "additional_components": [ "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C", "P38862", "YHR171W", "P40344", "YNR007C", "P38182", "YBL078C" ] }, "reaction_10779113": { "compartment": "compartment_70101", "id": "reaction_10779113", "reactome": "R-SCE-5679266", "name": "Beclin-1 complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779111" ], "products": [ "species_10779087" ], "modifiers": [], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W" ] }, "reaction_10769778": { "compartment": "compartment_17938", "id": "reaction_10769778", "reactome": "R-SCE-428007", "name": "Proton-coupled histidine and di-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427984", "species_428040" ], "products": [ "species_70106", "species_428003" ], "modifiers": [ [ "species_10769773", "catalyst" ] ], "additional_components": [ "CHEBI:90799", "CHEBI:32513", "CHEBI:32513", "CHEBI:46761", "YKR093W" ] }, "reaction_10787736": { "compartment": "compartment_70101", "id": "reaction_10787736", "reactome": "R-SCE-8959798", "name": "SLC30A10 transports Mn2+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29418" ], "products": [ "species_266099" ], "modifiers": [ [ "species_10787733", "catalyst" ] ], "additional_components": [ "P20107", "YMR243C", "P32798", "YOR316C" ] }, "reaction_10770232": { "compartment": "compartment_876", "id": "reaction_10770232", "reactome": "R-SCE-437300", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_437295" ], "products": [ "species_209799" ], "modifiers": [ [ "species_10770229", "catalyst" ] ], "additional_components": [ "YHR175W" ] }, "reaction_10770216": { "compartment": "compartment_876", "id": "reaction_10770216", "reactome": "R-SCE-435366", "name": "ZnT1 mediates the efflux of zinc from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_158417" ], "modifiers": [ [ "species_10770213", "catalyst" ] ], "additional_components": [ "YMR243C" ] }, "reaction_10770208": { "compartment": "compartment_876", "id": "reaction_10770208", "reactome": "R-SCE-434650", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_446589", "species_351626" ], "products": [ "species_70106", "species_446597" ], "modifiers": [ [ "species_10770205", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:16737", "LigandDisplayForward?ligandId=1231", "CHEBI:641", "CHEBI:6801", "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:16737", "LigandDisplayForward?ligandId=1231", "CHEBI:641", "CHEBI:6801", "P38767", "YHR032W", "Q05497", "YDR338C" ] }, "reaction_10769984": { "compartment": "compartment_876", "id": "reaction_10769984", "reactome": "R-SCE-429101", "name": "HMIT co-transports myo-inositol with a proton", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429130", "species_351626" ], "products": [ "species_70106", "species_426910" ], "modifiers": [ [ "species_10769981", "catalyst" ] ], "additional_components": [ "YDR497C" ] }, "reaction_10769870": { "compartment": "compartment_201753", "id": "reaction_10769870", "reactome": "R-SCE-428625", "name": "Vesicular inhibitory amino acid transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428548", "species_428592" ], "products": [ "species_70106", "species_428632" ], "modifiers": [ [ "species_10769867", "catalyst" ] ], "additional_components": [ "species_916850", "species_29424", "species_916850", "species_29424", "YJR001W" ] }, "reaction_10785998": { "compartment": "compartment_70101", "id": "reaction_10785998", "reactome": "R-SCE-8855062", "name": "SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162252", "species_71284" ], "products": [ "species_71285", "species_2162265" ], "modifiers": [ [ "species_10785995", "catalyst" ] ], "additional_components": [ "YNL003C" ] }, "reaction_10768477": { "compartment": "compartment_876", "id": "reaction_10768477", "reactome": "R-SCE-352158", "name": "SLC16A10-mediated uptake of aromatic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352161" ], "products": [ "species_352139" ], "modifiers": [ [ "species_10768474", "catalyst" ] ], "additional_components": [ "species_29502", "species_29500", "CHEBI:58315", "species_29502", "species_29500", "CHEBI:58315", "P25568", "YCL038C", "P53918", "YNL125C", "Q08777", "YOR306C", "Q08268", "YOL119C", "P36032", "YKL221W" ] }, "reaction_10778165": { "compartment": "compartment_70101", "id": "reaction_10778165", "reactome": "R-SCE-5627802", "name": "SLC26A4 transports I- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209785" ], "products": [ "species_209818" ], "modifiers": [ [ "species_10778162", "catalyst" ] ], "additional_components": [ "YPR003C" ] }, "reaction_10768673": { "compartment": "compartment_876", "id": "reaction_10768673", "reactome": "R-SCE-379432", "name": "SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29588", "species_379430" ], "products": [ "species_351964", "species_379440" ], "modifiers": [ [ "species_10768670", "catalyst" ] ], "additional_components": [ "species_379444", "species_1131871", "species_29468", "species_379444", "species_1131871", "species_29468", "P53341", "YGR292W", "P53051", "YGR287C", "P50276", "YGR055W", "P38734", "YHL036W", "P38158", "YBR299W", "P40884", "YJL216C", "P0CW41", "YJL221C", "P0CW40", "YIL172C", "Q08295", "YOL157C" ] }, "reaction_10769768": { "compartment": "compartment_876", "id": "reaction_10769768", "reactome": "R-SCE-427666", "name": "SLC26A3,6 exchange Cl- for HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111627", "species_188972" ], "products": [ "species_352022", "species_425425" ], "modifiers": [ [ "species_10769765", "catalyst" ] ], "additional_components": [ "P53394", "YPR003C" ] }, "reaction_10777542": { "compartment": "compartment_70101", "id": "reaction_10777542", "reactome": "R-SCE-5340130", "name": "CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5673778", "species_428040" ], "products": [ "species_70106", "species_379444" ], "modifiers": [ [ "species_10777539", "catalyst" ] ], "additional_components": [ "YCR075C" ] }, "reaction_10769759": { "compartment": "compartment_876", "id": "reaction_10769759", "reactome": "R-SCE-427570", "name": "Group 3 - Selective Cl- transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10769756", "catalyst" ] ], "additional_components": [ "P53394", "YPR003C" ] }, "reaction_10786838": { "compartment": "compartment_70101", "id": "reaction_10786838", "reactome": "R-SCE-8875871", "name": "SLC26A11 transports SO4(2-) from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648" ], "products": [ "species_174375" ], "modifiers": [ [ "species_10786835", "catalyst" ] ], "additional_components": [ "YBR294W" ] }, "reaction_10767238": { "compartment": "compartment_7660", "id": "reaction_10767238", "reactome": "R-SCE-198714", "name": "ERK5 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767234" ], "products": [ "species_10767236" ], "modifiers": [], "additional_components": [ "YPR054W", "YPR054W" ] }, "reaction_10778793": { "compartment": "compartment_70101", "id": "reaction_10778793", "reactome": "R-SCE-5674496", "name": "Activated MAPKs phosphorylate MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10778763" ], "products": [ "species_29370", "species_10778790" ], "modifiers": [ [ "species_10778780", "catalyst" ] ], "additional_components": [ "P06784", "YDL159W", "P06784", "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10779550": { "compartment": "compartment_7660", "id": "reaction_10779550", "reactome": "R-SCE-5687091", "name": "p-S MAPK6,4 binds MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775217", "species_10779544" ], "products": [ "species_10779548" ], "modifiers": [], "additional_components": [ "YKL171W", "YPR054W", "P41808", "YPR054W", "P36003", "YKL171W" ] }, "reaction_10780903": { "compartment": "compartment_70101", "id": "reaction_10780903", "reactome": "R-SCE-5690250", "name": "p-T182-MAPKAPK5 phoshphorylates DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10780891" ], "products": [ "species_29370", "species_10780900" ], "modifiers": [ [ "species_10780891", "catalyst" ] ], "additional_components": [ "P25294", "YNL007C", "P36003", "YKL171W", "P25294", "YNL007C", "P36003", "YKL171W", "P25294", "YNL007C", "P36003", "YKL171W" ] }, "reaction_10779572": { "compartment": "compartment_7660", "id": "reaction_10779572", "reactome": "R-SCE-5687109", "name": "MAPK4,6 translocate to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779563" ], "products": [ "species_10779557" ], "modifiers": [ [ "species_10779570", "catalyst" ] ], "additional_components": [ "P41808", "YPR054W", "P41808", "YPR054W", "YGR218W" ] }, "reaction_10779583": { "compartment": "compartment_7660", "id": "reaction_10779583", "reactome": "R-SCE-5687123", "name": "p-S115 MAPKAPK5 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779529" ], "products": [ "species_10779581" ], "modifiers": [], "additional_components": [ "YKL171W", "YKL171W" ] }, "reaction_10779542": { "compartment": "compartment_7660", "id": "reaction_10779542", "reactome": "R-SCE-5687088", "name": "PKA phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775217", "species_29358" ], "products": [ "species_113582", "species_10779529" ], "modifiers": [ [ "species_10779539", "catalyst" ] ], "additional_components": [ "YKL171W", "YKL171W", "P05986", "YKL166C", "P06245", "YPL203W", "P06244", "YJL164C" ] }, "reaction_10781177": { "compartment": "compartment_70101", "id": "reaction_10781177", "reactome": "R-SCE-5692770", "name": "SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781173", "species_10779577", "species_10779523" ], "products": [ "species_10781175" ], "modifiers": [], "additional_components": [ "P32457", "YLR314C", "Q07657", "YDL225W", "Q04921", "YDR218C", "P32468", "YHR107C", "P41901", "YGR059W", "P32458", "YJR076C", "YKL171W", "YPR054W", "P41808", "YPR054W", "P32457", "YLR314C", "Q07657", "YDL225W", "Q04921", "YDR218C", "P32468", "YHR107C", "P36003", "YKL171W", "P41901", "YGR059W", "P32458", "YJR076C" ] }, "reaction_10779565": { "compartment": "compartment_70101", "id": "reaction_10779565", "reactome": "R-SCE-5687107", "name": "MAPK4,6 translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779557" ], "products": [ "species_10779563" ], "modifiers": [], "additional_components": [ "P41808", "YPR054W", "P41808", "YPR054W" ] }, "reaction_10780893": { "compartment": "compartment_70101", "id": "reaction_10780893", "reactome": "R-SCE-5690245", "name": "p-T182 MAPKAPK5 binds DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779577", "species_10775708" ], "products": [ "species_10780891" ], "modifiers": [], "additional_components": [ "YKL171W", "YNL007C", "P25294", "YNL007C", "P36003", "YKL171W" ] }, "reaction_10779526": { "compartment": "compartment_70101", "id": "reaction_10779526", "reactome": "R-SCE-5687086", "name": "PAK1,2,3 phosphorylates MAPK6,4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779517", "species_113592" ], "products": [ "species_29370", "species_10779520" ], "modifiers": [ [ "species_10778157", "catalyst" ] ], "additional_components": [ "YPR054W", "YPR054W", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W" ] }, "reaction_10779575": { "compartment": "compartment_70101", "id": "reaction_10779575", "reactome": "R-SCE-5687112", "name": "MAPK6 is degraded by the 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779515" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "YPR054W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10781115": { "compartment": "compartment_7660", "id": "reaction_10781115", "reactome": "R-SCE-5692749", "name": "CDC14A,B bind MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781107", "species_10781109" ], "products": [ "species_10781113" ], "modifiers": [], "additional_components": [ "YPR054W", "YFR028C", "P41808", "YPR054W", "Q00684", "YFR028C" ] }, "reaction_10781120": { "compartment": "compartment_7660", "id": "reaction_10781120", "reactome": "R-SCE-5692754", "name": "CDC14A,B dephosphorylate p-3S,T MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10781113" ], "products": [ "species_113550", "species_10781117" ], "modifiers": [ [ "species_10781113", "catalyst" ] ], "additional_components": [ "P41808", "YPR054W", "Q00684", "YFR028C", "P41808", "YPR054W", "Q00684", "YFR028C", "P41808", "YPR054W", "Q00684", "YFR028C" ] }, "reaction_10779555": { "compartment": "compartment_7660", "id": "reaction_10779555", "reactome": "R-SCE-5687094", "name": "p-S MAPK6,4 phosphorylate MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779548" ], "products": [ "species_113582", "species_10779552" ], "modifiers": [ [ "species_10779548", "catalyst" ] ], "additional_components": [ "P41808", "YPR054W", "P36003", "YKL171W", "P41808", "YPR054W", "P36003", "YKL171W", "P41808", "YPR054W", "P36003", "YKL171W" ] }, "reaction_10779579": { "compartment": "compartment_7660", "id": "reaction_10779579", "reactome": "R-SCE-5687120", "name": "p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779552" ], "products": [ "species_10779577", "species_10779520" ], "modifiers": [], "additional_components": [ "P41808", "YPR054W", "P36003", "YKL171W", "YKL171W", "YPR054W" ] }, "reaction_10781140": { "compartment": "compartment_7660", "id": "reaction_10781140", "reactome": "R-SCE-5692764", "name": "MAPK6 binds CCND3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781136", "species_10779561" ], "products": [ "species_10781138" ], "modifiers": [ [ "species_10781109", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "YPR054W", "P13365", "YAL040C", "P20438", "YPL256C", "P41808", "YPR054W", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "YFR028C" ] }, "reaction_10770806": { "compartment": "compartment_70101", "id": "reaction_10770806", "reactome": "R-SCE-450463", "name": "MK2 phosphorylates ZFP36 (Tristetraproline, TTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770793", "species_113592" ], "products": [ "species_29370", "species_10770785" ], "modifiers": [ [ "species_10766447", "catalyst" ] ], "additional_components": [ "P47976", "YDR151C", "P38217", "YBR017C", "P47977", "YLR136C", "P47976", "YDR151C", "P38217", "YBR017C", "P47977", "YLR136C", "YKL171W" ] }, "reaction_10770831": { "compartment": "compartment_70101", "id": "reaction_10770831", "reactome": "R-SCE-450490", "name": "Protein Kinase B/Akt phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770810", "species_113592" ], "products": [ "species_29370", "species_10770828" ], "modifiers": [ [ "species_10767095", "catalyst" ] ], "additional_components": [ "P47976", "YDR151C", "P47976", "YDR151C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10770803": { "compartment": "compartment_70101", "id": "reaction_10770803", "reactome": "R-SCE-450431", "name": "ZFP36 (TTP) recruits RNA degradation activities", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770123", "species_10770057", "species_10770793", "species_10770799", "species_10770050" ], "products": [ "species_10770801" ], "modifiers": [], "additional_components": [ "P53859", "CSL4", "Q08285", "RRP40", "P53256", "RRP46", "P38792", "RRP4", "Q12277", "RRP42", "P48240", "MTR3", "Q08162", "DIS3", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "YNL118C", "P47976", "YDR151C", "P38217", "YBR017C", "P47977", "YLR136C", "YOL149W", "P47976", "YDR151C", "P53859", "CSL4", "Q08285", "RRP40", "P22147", "XRN1", "Q12277", "RRP42", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "P53550", "YNL118C", "P38217", "YBR017C", "P53256", "RRP46", "P38792", "RRP4", "P48240", "MTR3", "Q12517", "YOL149W", "Q08162", "DIS3", "P47977", "YLR136C" ] }, "reaction_10770824": { "compartment": "compartment_70101", "id": "reaction_10770824", "reactome": "R-SCE-450488", "name": "BRF1 Complex recruits RNA degradation activities", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770123", "species_10770810", "species_10770057", "species_10770799", "species_10770050" ], "products": [ "species_10770822" ], "modifiers": [], "additional_components": [ "P53859", "CSL4", "Q08285", "RRP40", "P53256", "RRP46", "P38792", "RRP4", "Q12277", "RRP42", "P48240", "MTR3", "Q08162", "DIS3", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "P47976", "YDR151C", "YNL118C", "YOL149W", "P47976", "YDR151C", "P53859", "CSL4", "Q08285", "RRP40", "P22147", "XRN1", "Q12277", "RRP42", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "P53550", "YNL118C", "P53256", "RRP46", "P38792", "RRP4", "P48240", "MTR3", "Q12517", "YOL149W", "Q08162", "DIS3" ] }, "reaction_10770795": { "compartment": "compartment_70101", "id": "reaction_10770795", "reactome": "R-SCE-450400", "name": "ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770791", "species_450597", "species_10770767" ], "products": [ "species_10770793" ], "modifiers": [], "additional_components": [ "P47976", "YDR151C", "P47977", "YLR136C", "YBR017C", "P47976", "YDR151C", "P38217", "YBR017C", "P47977", "YLR136C" ] }, "reaction_10770820": { "compartment": "compartment_70101", "id": "reaction_10770820", "reactome": "R-SCE-450474", "name": "MK2 phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770810", "species_113592" ], "products": [ "species_29370", "species_10770818" ], "modifiers": [ [ "species_10766447", "catalyst" ] ], "additional_components": [ "P47976", "YDR151C", "P47976", "YDR151C", "YKL171W" ] }, "reaction_10770839": { "compartment": "compartment_70101", "id": "reaction_10770839", "reactome": "R-SCE-450517", "name": "Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770808", "species_450523" ], "products": [ "species_10770810" ], "modifiers": [], "additional_components": [ "YDR151C", "P47976", "YDR151C" ] }, "reaction_10768801": { "compartment": "compartment_70101", "id": "reaction_10768801", "reactome": "R-SCE-381111", "name": "EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762638", "species_113592" ], "products": [ "species_29370", "species_10768798" ], "modifiers": [ [ "species_10768776", "catalyst" ] ], "additional_components": [ "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "P47042", "YJL057C" ] }, "reaction_10768778": { "compartment": "compartment_12045", "id": "reaction_10768778", "reactome": "R-SCE-381087", "name": "Dimerization of PERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768767" ], "products": [ "species_10768776" ], "modifiers": [], "additional_components": [ "YJL057C", "P47042", "YJL057C" ] }, "reaction_10771292": { "compartment": "compartment_70101", "id": "reaction_10771292", "reactome": "R-SCE-888592", "name": "Loading of GABA into clathrin sculpted GABA transport vesicle lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352011" ], "products": [ "species_428571" ], "modifiers": [ [ "species_10771289", "catalyst" ] ], "additional_components": [ "YJR001W" ] }, "reaction_10771287": { "compartment": "compartment_5460", "id": "reaction_10771287", "reactome": "R-SCE-888548", "name": "ALDH5A1 dehydrogenates SUCCSA to SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_880046", "species_113526" ], "products": [ "species_113536", "species_29362", "species_113529" ], "modifiers": [ [ "species_10771284", "catalyst" ] ], "additional_components": [ "P38067", "YBR006W" ] }, "reaction_10771335": { "compartment": "compartment_5460", "id": "reaction_10771335", "reactome": "R-SCE-916855", "name": "PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_916850" ], "products": [ "species_113552", "species_880046" ], "modifiers": [ [ "species_10771332", "catalyst" ] ], "additional_components": [ "CHEBI:33739", "P17649", "YGR019W" ] }, "reaction_10777469": { "compartment": "compartment_70101", "id": "reaction_10777469", "reactome": "R-SCE-5324632", "name": "Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777464", "species_5324631" ], "products": [ "species_10775732", "species_10775828", "species_10768212", "species_10777466" ], "modifiers": [ [ "species_10777464", "catalyst" ] ], "additional_components": [ "P02829", "YPL240C", "P53973", "YNL021W", "P28707", "YKL117W", "P38889", "YHR206W", "P10961", "YGL073W", "P15108", "YMR186W", "P25694", "YDL126C", "P38889", "YHR206W", "P10961", "YGL073W", "P02829", "YPL240C", "P15108", "YMR186W", "YKL117W", "P53973", "YNL021W", "P25694", "YDL126C", "P02829", "YPL240C", "P53973", "YNL021W", "P28707", "YKL117W", "P38889", "YHR206W", "P10961", "YGL073W", "P15108", "YMR186W", "P25694", "YDL126C" ] }, "reaction_10775838": { "compartment": "compartment_7660", "id": "reaction_10775838", "reactome": "R-SCE-3371518", "name": "SIRT1 binds to HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775800", "species_10769730" ], "products": [ "species_10775802" ], "modifiers": [], "additional_components": [ "P36016", "YKL073W", "P25294", "YNL007C", "P22202", "YER103W", "P38889", "YHR206W", "P10961", "YGL073W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "YDL042C", "P36016", "YKL073W", "P25294", "YNL007C", "P06700", "YDL042C", "P22202", "YER103W", "P38889", "YHR206W", "P10961", "YGL073W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C" ] }, "reaction_10776963": { "compartment": "compartment_7660", "id": "reaction_10776963", "reactome": "R-SCE-5082409", "name": "Dissociation of HSF1:HSP90 complex in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776961" ], "products": [ "species_10776953", "species_10776959", "species_10776931" ], "modifiers": [], "additional_components": [ "P02829", "YPL240C", "P28707", "YKL117W", "P38889", "YHR206W", "P10961", "YGL073W", "P15108", "YMR186W", "YKL117W", "P02829", "YPL240C", "P15108", "YMR186W", "P38889", "YHR206W", "P10961", "YGL073W" ] }, "reaction_10776071": { "compartment": "compartment_70101", "id": "reaction_10776071", "reactome": "R-SCE-3697860", "name": "SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776067", "species_10775367" ], "products": [ "species_10776069" ], "modifiers": [], "additional_components": [ "species_158417", "CHEBI:49552", "P40202", "CCS1", "species_158417", "P00445", "SOD1", "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1" ] }, "reaction_10776933": { "compartment": "compartment_7660", "id": "reaction_10776933", "reactome": "R-SCE-5082391", "name": "Trimerization of HSF1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776931" ], "products": [ "species_10775810" ], "modifiers": [], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W" ] }, "reaction_10787563": { "compartment": "compartment_70101", "id": "reaction_10787563", "reactome": "R-SCE-8951723", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776069" ], "products": [ "species_10775369" ], "modifiers": [], "additional_components": [ "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1", "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1" ] }, "reaction_10775817": { "compartment": "compartment_7660", "id": "reaction_10775817", "reactome": "R-SCE-3371467", "name": "SIRT1 deacetylates HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_427523", "species_10775802" ], "products": [ "species_427498", "species_427497", "species_10775814", "species_10769730" ], "modifiers": [ [ "species_10775802", "catalyst" ] ], "additional_components": [ "P36016", "YKL073W", "P25294", "YNL007C", "P06700", "YDL042C", "P22202", "YER103W", "P38889", "YHR206W", "P10961", "YGL073W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P36016", "YKL073W", "P25294", "YNL007C", "P22202", "YER103W", "P38889", "YHR206W", "P09435", "YBL075C", "P10592", "YLL024C", "P10961", "YGL073W", "P10591", "YAL005C", "YDL042C", "P36016", "YKL073W", "P25294", "YNL007C", "P06700", "YDL042C", "P22202", "YER103W", "P38889", "YHR206W", "P10961", "YGL073W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C" ] }, "reaction_10775358": { "compartment": "compartment_70101", "id": "reaction_10775358", "reactome": "R-SCE-3299691", "name": "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_1222424" ], "products": [ "species_29408", "species_29368" ], "modifiers": [ [ "species_10775355", "catalyst" ] ], "additional_components": [ "species_158417", "P00445", "SOD1", "species_437295" ] }, "reaction_10776951": { "compartment": "compartment_7660", "id": "reaction_10776951", "reactome": "R-SCE-5082405", "name": "Phosphorylation of HSF1 at Ser326 induces transactivation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775810", "species_29358" ], "products": [ "species_113582", "species_10776917" ], "modifiers": [ [ "species_10776948", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "P32600", "YKL203C", "P41318", "YNL006W", "P38873", "YHR186C" ] }, "reaction_10775376": { "compartment": "compartment_70101", "id": "reaction_10775376", "reactome": "R-SCE-3299753", "name": "CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775369" ], "products": [ "species_10775373", "species_10775355" ], "modifiers": [ [ "species_10775369", "catalyst" ] ], "additional_components": [ "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1", "species_158417", "CHEBI:49552", "P40202", "CCS1", "species_158417", "P00445", "SOD1", "species_437295", "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1" ] }, "reaction_10776841": { "compartment": "compartment_70101", "id": "reaction_10776841", "reactome": "R-SCE-4793911", "name": "MAPKAPK2 phosphorylates HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775732", "species_113592" ], "products": [ "species_29370", "species_10776838" ], "modifiers": [ [ "species_10766440", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "YKL171W" ] }, "reaction_10777933": { "compartment": "compartment_70101", "id": "reaction_10777933", "reactome": "R-SCE-5618107", "name": "ATP binding to HSP90 triggers conformation change", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10775834" ], "products": [ "species_10777927" ], "modifiers": [], "additional_components": [ "P36016", "YKL073W", "P02829", "YPL240C", "P22202", "YER103W", "species_29370", "P15705", "YOR027W", "P09435", "YBL075C", "P10592", "YLL024C", "P15108", "YMR186W", "P10591", "YAL005C", "P36016", "YKL073W", "P02829", "YPL240C", "P22202", "YER103W", "P15705", "YOR027W", "species_29370", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P15108", "YMR186W", "P10591", "YAL005C" ] }, "reaction_10788859": { "compartment": "compartment_17938", "id": "reaction_10788859", "reactome": "R-SCE-9640195", "name": "RRAGA,B hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788854" ], "products": [ "species_10788856", "species_29372" ], "modifiers": [ [ "species_10788854", "catalyst" ] ], "additional_components": [ "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P25378", "YCR027C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P25378", "YCR027C", "species_29438", "P38873", "YHR186C", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P32600", "YKL203C", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P25378", "YCR027C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10776883": { "compartment": "compartment_17963", "id": "reaction_10776883", "reactome": "R-SCE-4837364", "name": "Secretion of SOD3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776881" ], "products": [ "species_10775345" ], "modifiers": [], "additional_components": [ "species_158417", "P00445", "SOD1", "species_437295", "species_158417", "P00445", "SOD1", "species_437295" ] }, "reaction_10764183": { "compartment": "compartment_17951", "id": "reaction_10764183", "reactome": "R-SCE-76031", "name": "2 H2O2 => O2 + 2 H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113575" ], "products": [ "species_141343", "species_113535" ], "modifiers": [ [ "species_10764180", "catalyst" ] ], "additional_components": [ "P15202", "YDR256C", "species_189444", "species_113602" ] }, "reaction_10788844": { "compartment": "compartment_17938", "id": "reaction_10788844", "reactome": "R-SCE-9639286", "name": "RRAGC,D exchanges GTP for GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788837", "species_29420" ], "products": [ "species_29438", "species_10788841" ], "modifiers": [ [ "species_10788837", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10775629": { "compartment": "compartment_70616", "id": "reaction_10775629", "reactome": "R-SCE-3341294", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_10765569" ], "products": [ "species_10765567", "species_189461" ], "modifiers": [], "additional_components": [ "P00045", "YEL039C", "P00044", "YJR048W", "CHEBI:38574", "P00045", "YEL039C", "P00044", "YJR048W", "CHEBI:38573" ] }, "reaction_10788899": { "compartment": "compartment_17938", "id": "reaction_10788899", "reactome": "R-SCE-9646468", "name": "mTORC1 binds RHEB:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765837", "species_10788852" ], "products": [ "species_10788854" ], "modifiers": [], "additional_components": [ "P25378", "YCR027C", "species_29438", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P25378", "YCR027C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10775719": { "compartment": "compartment_70101", "id": "reaction_10775719", "reactome": "R-SCE-3371422", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775714" ], "products": [ "species_29372", "species_10775716" ], "modifiers": [ [ "species_10775714", "catalyst" ], [ "species_10775712", "catalyst" ] ], "additional_components": [ "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_29370", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W" ] }, "reaction_10776175": { "compartment": "compartment_17927", "id": "reaction_10776175", "reactome": "R-SCE-3777112", "name": "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_163953" ], "products": [ "species_189481", "species_189461" ], "modifiers": [ [ "species_10776172", "catalyst" ] ], "additional_components": [ "species_158417", "P00445", "SOD1", "species_437295" ] }, "reaction_10775836": { "compartment": "compartment_70101", "id": "reaction_10775836", "reactome": "R-SCE-3371503", "name": "STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775828", "species_10775822", "species_10775716" ], "products": [ "species_10775712", "species_10775834" ], "modifiers": [], "additional_components": [ "P02829", "YPL240C", "P15108", "YMR186W", "YOR027W", "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_29370", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P36016", "YKL073W", "P02829", "YPL240C", "P22202", "YER103W", "species_29370", "P15705", "YOR027W", "P09435", "YBL075C", "P10592", "YLL024C", "P15108", "YMR186W", "P10591", "YAL005C" ] }, "reaction_10775760": { "compartment": "compartment_70101", "id": "reaction_10775760", "reactome": "R-SCE-3371435", "name": "Constitutive phosphorylation by GSK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775732", "species_113592" ], "products": [ "species_29370", "species_10775740" ], "modifiers": [ [ "species_10775757", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "P50873", "YDL079C", "P38615", "YMR139W", "P21965", "YNL307C" ] }, "reaction_10775348": { "compartment": "compartment_984", "id": "reaction_10775348", "reactome": "R-SCE-3299682", "name": "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3299686", "species_351626" ], "products": [ "species_351629", "species_352327" ], "modifiers": [ [ "species_10775345", "catalyst" ] ], "additional_components": [ "species_158417", "P00445", "SOD1", "species_437295" ] }, "reaction_10775848": { "compartment": "compartment_70101", "id": "reaction_10775848", "reactome": "R-SCE-3371527", "name": "HSF1 trimer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775846" ], "products": [ "species_10775810" ], "modifiers": [], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W" ] }, "reaction_10775875": { "compartment": "compartment_70101", "id": "reaction_10775875", "reactome": "R-SCE-3371590", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775871", "species_10775873" ], "products": [ "species_10775714" ], "modifiers": [], "additional_components": [ "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P36016", "YKL073W", "P22202", "YER103W", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C" ] }, "reaction_10775865": { "compartment": "compartment_70101", "id": "reaction_10775865", "reactome": "R-SCE-3371531", "name": "Constitutive phosphorylation by pERK1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775732", "species_113592" ], "products": [ "species_29370", "species_10775856" ], "modifiers": [ [ "species_10775862", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10775869": { "compartment": "compartment_70101", "id": "reaction_10775869", "reactome": "R-SCE-3371586", "name": "Dissociation of cytosolic HSF1:HSP90 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775867" ], "products": [ "species_10775732", "species_10775828", "species_10768212" ], "modifiers": [], "additional_components": [ "P02829", "YPL240C", "P28707", "YKL117W", "P38889", "YHR206W", "P10961", "YGL073W", "P15108", "YMR186W", "P38889", "YHR206W", "P10961", "YGL073W", "P02829", "YPL240C", "P15108", "YMR186W", "YKL117W" ] }, "reaction_10788872": { "compartment": "compartment_17938", "id": "reaction_10788872", "reactome": "R-SCE-9645598", "name": "RRAGC,D hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788837" ], "products": [ "species_10788841", "species_29372" ], "modifiers": [ [ "species_10788837", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10776919": { "compartment": "compartment_7660", "id": "reaction_10776919", "reactome": "R-SCE-5082356", "name": "HSF1-mediated gene expression", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775812" ], "products": [ "species_10776897" ], "modifiers": [ [ "species_10776907", "catalyst" ], [ "species_10776917", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P25294", "YNL007C", "P02829", "YPL240C", "P10592", "YLL024C", "P15108", "YMR186W", "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W" ] }, "reaction_10788874": { "compartment": "compartment_17938", "id": "reaction_10788874", "reactome": "R-SCE-9645608", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788848", "species_10788850" ], "products": [ "species_10788852" ], "modifiers": [], "additional_components": [ "P32600", "YKL203C", "P41318", "YNL006W", "P38873", "YHR186C", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10775877": { "compartment": "compartment_70101", "id": "reaction_10775877", "reactome": "R-SCE-3371591", "name": "Trimerization of cytosolic HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775732" ], "products": [ "species_10775846" ], "modifiers": [ [ "species_10765400", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7" ] }, "reaction_10775337": { "compartment": "compartment_5460", "id": "reaction_10775337", "reactome": "R-SCE-3299680", "name": "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3299683", "species_113529" ], "products": [ "species_113533", "species_1614617" ], "modifiers": [ [ "species_10775334", "catalyst" ] ], "additional_components": [ "P00447", "YHR008C", "species_113527" ] }, "reaction_10775625": { "compartment": "compartment_5460", "id": "reaction_10775625", "reactome": "R-SCE-3323079", "name": "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_1655882", "species_113529" ], "products": [ "species_113563", "species_1655887" ], "modifiers": [ [ "species_10775622", "catalyst" ] ], "additional_components": [ "P41921", "YPL091W", "species_113596" ] }, "reaction_10769335": { "compartment": "compartment_70101", "id": "reaction_10769335", "reactome": "R-SCE-418456", "name": "cGMP is degraded by PDEs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30991" ], "products": [ "species_113578" ], "modifiers": [ [ "species_10769328", "catalyst" ] ], "additional_components": [ "YOR360C" ] }, "reaction_10788618": { "compartment": "compartment_70101", "id": "reaction_10788618", "reactome": "R-SCE-9610166", "name": "p-T,Y MAPK dimers translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775862" ], "products": [ "species_10767244" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10778778": { "compartment": "compartment_70101", "id": "reaction_10778778", "reactome": "R-SCE-5674385", "name": "p-T,Y MAPKs dimerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772586" ], "products": [ "species_10775862" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10788635": { "compartment": "compartment_7660", "id": "reaction_10788635", "reactome": "R-SCE-9612509", "name": "SGK phosphorylates SRF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10788623" ], "products": [ "species_113582", "species_10788626" ], "modifiers": [ [ "species_10788632", "catalyst" ] ], "additional_components": [ "YMR043W", "YMR043W", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10771748": { "compartment": "compartment_70101", "id": "reaction_10771748", "reactome": "R-SCE-927889", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771743", "species_113592" ], "products": [ "species_29370", "species_10771745" ], "modifiers": [ [ "species_10771743", "catalyst" ] ], "additional_components": [ "P10622", "YDL130W", "P38798", "YHR077C", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P38760", "YHR015W", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P12385", "SUP45", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P04147", "YER165W", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P39684", "YFR023W", "P38061", "RPL32", "P14120", "RPL30", "species_29420", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P39936", "YGL049C", "P0CX82", "RPL19A", "Q12099", "YDR021W", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P05453", "SUP35", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P48412", "YGR072W", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "Q08920", "YPL178W", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P30771", "YMR080C", "P34160", "YMR125W", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771730" ], "products": [ "species_10771693" ], "modifiers": [ [ "species_10771730", "catalyst" ] ], "additional_components": [ "P10622", "YDL130W", "P38798", "YHR077C", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "P40456", "YIL151C", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P17214", "YLR233C", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P38760", "YHR015W", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P12385", "SUP45", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P04147", "YER165W", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "Q03466", "YDR206W", "P39684", "YFR023W", "P38061", "RPL32", "P14120", "RPL30", "species_29420", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771633", "species_10771609" ], "products": [ "species_10771635" ], "modifiers": [], "additional_components": [ "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P38760", "YHR015W", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P12385", "SUP45", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P04147", "YER165W", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P39684", "YFR023W", "P38061", "RPL32", "P14120", "RPL30", "species_29420", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P39936", "YGL049C", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P05453", "SUP35", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "Q08920", "YPL178W", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P34160", "YMR125W", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B", "YMR080C", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P38760", "YHR015W", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P12385", "SUP45", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P04147", "YER165W", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P39684", "YFR023W", "P38061", "RPL32", "P14120", "RPL30", "species_29420", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P39936", "YGL049C", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P05453", "SUP35", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "Q08920", "YPL178W", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P30771", "YMR080C", "P34160", "YMR125W", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B" ] }, "reaction_10777503": { "compartment": "compartment_263163", "id": "reaction_10777503", "reactome": "R-SCE-5333658", "name": "CLAT:AP1:CLVS bind PI(3,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5334668", "species_10777499" ], "products": [ "species_10777501" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "Q12028", "YPR029C", "P22137", "YGL206C", "Q00776", "YPL259C", "P35181", "YLR170C", "species_6809774", "P17891", "YGR167W", "P36000", "YKL135C", "Q12028", "YPR029C", "P22137", "YGL206C", "Q00776", "YPL259C", "P35181", "YLR170C" ] }, "reaction_10764574": { "compartment": "compartment_70101", "id": "reaction_10764574", "reactome": "R-SCE-109857", "name": "MAP2K1 binds MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764553", "species_10764570" ], "products": [ "species_10764572" ], "modifiers": [], "additional_components": [ "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10764621": { "compartment": "compartment_70101", "id": "reaction_10764621", "reactome": "R-SCE-109863", "name": "Dissociation of p-T,Y-MAPK3:MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764600" ], "products": [ "species_10764553", "species_10764598" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10786323": { "compartment": "compartment_70101", "id": "reaction_10786323", "reactome": "R-SCE-8866275", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786276", "species_10786319" ], "products": [ "species_10786321" ], "modifiers": [], "additional_components": [ "YMR276W", "Q07872", "YLL038C", "Q05785", "YLR206W", "P34216", "YBL047C", "P39013", "YNL084C", "Q03769", "YDR153C", "P47160", "YJR125C", "P32521", "YIR006C", "Q12518", "YDL161W", "Q07872", "YLL038C", "Q05785", "YLR206W", "P34216", "YBL047C", "P39013", "YNL084C", "P48510", "YMR276W", "Q03769", "YDR153C", "P47160", "YJR125C", "P32521", "YIR006C", "Q12518", "YDL161W" ] }, "reaction_10786337": { "compartment": "compartment_876", "id": "reaction_10786337", "reactome": "R-SCE-8866277", "name": "AP-2 directly binds some endocytic cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786331", "species_10786030" ], "products": [ "species_10786333" ], "modifiers": [ [ "species_10786335", "inhibitor" ] ], "additional_components": [ "P0CE68", "YKR103W", "P12866", "YKL209C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "Q00381", "YJR058C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "P0CE68", "YKR103W", "Q00381", "YJR058C", "P12866", "YKL209C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "species_9648300", "Q00381", "YJR058C" ] }, "reaction_10786206": { "compartment": "compartment_70101", "id": "reaction_10786206", "reactome": "R-SCE-8863727", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781023", "species_10786204" ], "products": [ "species_10786190" ], "modifiers": [], "additional_components": [ "YDR139C", "Q99186", "YOL062C", "P38700", "YHL019C", "Q99186", "YOL062C", "P38700", "YHL019C" ] }, "reaction_10786140": { "compartment": "compartment_876", "id": "reaction_10786140", "reactome": "R-SCE-8856813", "name": "AAK1 phosphorylates AP-2 mu subunit at T156", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10786130" ], "products": [ "species_29370", "species_10786137" ], "modifiers": [ [ "species_10786130", "catalyst" ] ], "additional_components": [ "P25623", "YCR030C", "P17891", "YGR167W", "P53974", "YNL020C", "P36000", "YKL135C", "P34216", "YBL047C", "P38065", "YBL037W", "P38080", "YBR059C", "Q00381", "YJR058C", "Q05080", "YMR032W", "P39013", "YNL084C", "P27351", "YJR005W", "P43556", "YFL047W", "P22137", "YGL206C", "Q99186", "YOL062C", "P32521", "YIR006C", "P40494", "YIL095W", "species_179856", "P25623", "YCR030C", "P17891", "YGR167W", "P53974", "YNL020C", "P36000", "YKL135C", "P34216", "YBL047C", "P38065", "YBL037W", "P38080", "YBR059C", "Q00381", "YJR058C", "Q05080", "YMR032W", "P39013", "YNL084C", "P27351", "YJR005W", "P43556", "YFL047W", "P22137", "YGL206C", "Q99186", "YOL062C", "P32521", "YIR006C", "P40494", "YIL095W", "species_179856", "P25623", "YCR030C", "P17891", "YGR167W", "P53974", "YNL020C", "P36000", "YKL135C", "P34216", "YBL047C", "P38065", "YBL037W", "P38080", "YBR059C", "Q00381", "YJR058C", "Q05080", "YMR032W", "P39013", "YNL084C", "P27351", "YJR005W", "P43556", "YFL047W", "P22137", "YGL206C", "Q99186", "YOL062C", "P32521", "YIR006C", "P40494", "YIL095W", "species_179856" ] }, "reaction_10786527": { "compartment": "compartment_876", "id": "reaction_10786527", "reactome": "R-SCE-8868066", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10773422", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10786779": { "compartment": "compartment_876", "id": "reaction_10786779", "reactome": "R-SCE-8871196", "name": "Initial binding of AP-2 and clathrin to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769532", "species_179856", "species_10786030" ], "products": [ "species_10786116" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P22137", "YGL206C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "species_179856" ] }, "reaction_10786466": { "compartment": "compartment_876", "id": "reaction_10786466", "reactome": "R-SCE-8867613", "name": "PICALM binds R-SNAREs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786449", "species_10786462" ], "products": [ "species_10786464" ], "modifiers": [], "additional_components": [ "P33328", "YOR327C", "P31109", "YAL030W", "P38856", "YHR161C", "P53309", "YGR241C", "P38856", "YHR161C", "P53309", "YGR241C", "P33328", "YOR327C", "P31109", "YAL030W" ] }, "reaction_10789079": { "compartment": "compartment_70101", "id": "reaction_10789079", "reactome": "R-SCE-9681616", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9648300", "species_10786030" ], "products": [ "species_10786335" ], "modifiers": [], "additional_components": [ "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "Q00381", "YJR058C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "species_9648300", "Q00381", "YJR058C" ] }, "reaction_10786167": { "compartment": "compartment_876", "id": "reaction_10786167", "reactome": "R-SCE-8862280", "name": "FCHo proteins bind nascent clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786094", "species_10786063", "species_10786116", "species_10786110", "species_10786102", "species_10786124" ], "products": [ "species_10786126" ], "modifiers": [], "additional_components": [ "P25623", "YCR030C", "Q05080", "YMR032W", "P43556", "YFL047W", "P34216", "YBL047C", "P39013", "YNL084C", "P32521", "YIR006C", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "species_179856", "P34216", "YBL047C", "P39013", "YNL084C", "P32521", "YIR006C", "P34216", "YBL047C", "P39013", "YNL084C", "P32521", "YIR006C", "P25623", "YCR030C", "Q05080", "YMR032W", "P43556", "YFL047W", "P17891", "YGR167W", "P25623", "YCR030C", "P36000", "YKL135C", "P38065", "YBL037W", "P34216", "YBL047C", "Q00381", "YJR058C", "P27351", "YJR005W", "Q05080", "YMR032W", "P39013", "YNL084C", "P22137", "YGL206C", "Q99186", "YOL062C", "P43556", "YFL047W", "P32521", "YIR006C", "species_179856" ] }, "reaction_10765839": { "compartment": "compartment_17938", "id": "reaction_10765839", "reactome": "R-SCE-165195", "name": "GTP loading by Rheb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10765835" ], "products": [ "species_10765837", "species_29420" ], "modifiers": [], "additional_components": [ "species_29420", "P25378", "YCR027C", "P25378", "YCR027C", "species_29438" ] }, "reaction_10778419": { "compartment": "compartment_70101", "id": "reaction_10778419", "reactome": "R-SCE-5653957", "name": "Rag dimer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778402", "species_10778415" ], "products": [ "species_10778417" ], "modifiers": [], "additional_components": [ "Q00582", "YML121W", "species_29438", "species_29420", "P53290", "YGR163W", "species_29420", "P53290", "YGR163W", "Q00582", "YML121W", "species_29438" ] }, "reaction_10768750": { "compartment": "compartment_70101", "id": "reaction_10768750", "reactome": "R-SCE-380930", "name": "Phosphorylated AMPK binds AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767428", "species_76577" ], "products": [ "species_10768748" ], "modifiers": [], "additional_components": [ "P36002", "YKL198C", "P34164", "YGL208W", "Q04739", "YER027C", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "P36002", "YKL198C", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C" ] }, "reaction_10787858": { "compartment": "compartment_5460", "id": "reaction_10787858", "reactome": "R-SCE-8986181", "name": "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787850" ], "products": [], "modifiers": [ [ "species_10787855", "catalyst" ] ], "additional_components": [ "P53193", "JAC1", "P05150", "YJL088W", "Q07540", "YFH1", "P19882", "HSP60", "YDR430C" ] }, "reaction_10773966": { "compartment": "compartment_70616", "id": "reaction_10773966", "reactome": "R-SCE-1955380", "name": "TIMM9:TIMM10 transfers proteins to TIMM22", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773936", "species_10773958", "species_10773960" ], "products": [ "species_10773964" ], "modifiers": [], "additional_components": [ "P32897", "TIM23", "P18238", "YBR085W", "P18239", "YBL030C", "O74700", "TIM9", "P39515", "TIM17", "Q12328", "TIM22", "P87108", "TIM10", "Q06510", "TAZ1", "P04710", "AAC1", "P32897", "TIM23", "P18238", "YBR085W", "P18239", "YBL030C", "O74700", "TIM9", "P39515", "TIM17", "Q12328", "TIM22", "Q06510", "TAZ1", "P87108", "TIM10", "P04710", "AAC1" ] }, "reaction_10787754": { "compartment": "compartment_70101", "id": "reaction_10787754", "reactome": "R-SCE-8981553", "name": "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10787751", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10771210": { "compartment": "compartment_20699", "id": "reaction_10771210", "reactome": "R-SCE-742354", "name": "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756" ], "products": [ "species_914003" ], "modifiers": [ [ "species_10771207", "catalyst" ] ], "additional_components": [ "YEL004W" ] }, "reaction_10777534": { "compartment": "compartment_70101", "id": "reaction_10777534", "reactome": "R-SCE-5339538", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10777531", "catalyst" ] ], "additional_components": [ "P48439", "YOR085W", "Q03723", "YML019W" ] }, "reaction_10787772": { "compartment": "compartment_70101", "id": "reaction_10787772", "reactome": "R-SCE-8981574", "name": "GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10766510", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10777511": { "compartment": "compartment_70101", "id": "reaction_10777511", "reactome": "R-SCE-5336466", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29926" ], "products": [ "species_109496" ], "modifiers": [ [ "species_10777508", "catalyst" ] ], "additional_components": [ "YPL060W" ] }, "reaction_10770623": { "compartment": "compartment_70101", "id": "reaction_10770623", "reactome": "R-SCE-450092", "name": "GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770619" ], "products": [ "species_113592", "species_10770617" ], "modifiers": [], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C", "species_113592", "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10787104": { "compartment": "compartment_70101", "id": "reaction_10787104", "reactome": "R-SCE-8932851", "name": "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8932838" ], "products": [ "species_8932842" ], "modifiers": [ [ "species_10787101", "catalyst" ] ], "additional_components": [ "CHEBI:32513", "species_1131871", "species_29468", "CHEBI:32513", "species_1131871", "species_29468", "YOL092W" ] }, "reaction_10771591": { "compartment": "compartment_74700", "id": "reaction_10771591", "reactome": "R-SCE-917841", "name": "Acidification of Tf:TfR1 containing endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113592", "species_29356" ], "products": [ "species_29370", "species_74722", "species_29372" ], "modifiers": [ [ "species_10763690", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "P23968", "YHR026W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10771200": { "compartment": "compartment_20699", "id": "reaction_10771200", "reactome": "R-SCE-727759", "name": "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183" ], "products": [ "species_727753" ], "modifiers": [ [ "species_10771197", "catalyst" ] ], "additional_components": [ "YBR220C" ] }, "reaction_10770621": { "compartment": "compartment_70101", "id": "reaction_10770621", "reactome": "R-SCE-450088", "name": "GLUT1 tetramer binds 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10770617" ], "products": [ "species_10770619" ], "modifiers": [], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C", "P38142", "YBR241C", "P53142", "YGL104C", "species_113592" ] }, "reaction_10769976": { "compartment": "compartment_876", "id": "reaction_10769976", "reactome": "R-SCE-429036", "name": "SLC2A9 transports Fru, Glc, urate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429078" ], "products": [ "species_429148" ], "modifiers": [ [ "species_10769973", "catalyst" ] ], "additional_components": [ "species_70113", "species_29532", "CHEBI:17775", "species_70113", "species_29532", "CHEBI:17775", "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10771269": { "compartment": "compartment_876", "id": "reaction_10771269", "reactome": "R-SCE-879575", "name": "SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879603" ], "products": [ "species_879628" ], "modifiers": [ [ "species_10771266", "catalyst" ] ], "additional_components": [ "CHEBI:18332", "CHEBI:28774", "CHEBI:18332", "CHEBI:28774", "P25568", "YCL038C", "P53918", "YNL125C", "Q08777", "YOR306C", "Q08268", "YOL119C", "P36032", "YKL221W" ] }, "reaction_10777522": { "compartment": "compartment_70101", "id": "reaction_10777522", "reactome": "R-SCE-5339528", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10777519", "catalyst" ] ], "additional_components": [ "YOR085W" ] }, "reaction_10787770": { "compartment": "compartment_70101", "id": "reaction_10787770", "reactome": "R-SCE-8981570", "name": "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10787767", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10769950": { "compartment": "compartment_876", "id": "reaction_10769950", "reactome": "R-SCE-428779", "name": "GLUT7 and GLUT11 transport glucose and fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428819" ], "products": [ "species_428802" ], "modifiers": [ [ "species_10769947", "catalyst" ] ], "additional_components": [ "species_70113", "species_29532", "species_70113", "species_29532", "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10770626": { "compartment": "compartment_70101", "id": "reaction_10770626", "reactome": "R-SCE-450095", "name": "GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70113" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10766510", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10771213": { "compartment": "compartment_20699", "id": "reaction_10771213", "reactome": "R-SCE-742373", "name": "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742353" ], "products": [ "species_742361" ], "modifiers": [ [ "species_10771207", "catalyst" ] ], "additional_components": [ "YEL004W" ] }, "reaction_10787759": { "compartment": "compartment_70101", "id": "reaction_10787759", "reactome": "R-SCE-8981564", "name": "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10787756", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C" ] }, "reaction_10777514": { "compartment": "compartment_70101", "id": "reaction_10777514", "reactome": "R-SCE-5339524", "name": "GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10770617", "catalyst" ], [ "species_113592", "inhibitor" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10787519": { "compartment": "compartment_70616", "id": "reaction_10787519", "reactome": "R-SCE-8949688", "name": "SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8949220", "species_2889072" ], "products": [ "species_8949232", "species_2889083" ], "modifiers": [ [ "species_10787516", "catalyst" ] ], "additional_components": [ "YJR106W" ] }, "reaction_10764584": { "compartment": "compartment_70101", "id": "reaction_10764584", "reactome": "R-SCE-109858", "name": "MAP2K2 binds MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764580", "species_10764578" ], "products": [ "species_10764582" ], "modifiers": [], "additional_components": [ "YBL016W", "YDL159W", "P16892", "YBL016W", "P06784", "YDL159W" ] }, "reaction_10764623": { "compartment": "compartment_70101", "id": "reaction_10764623", "reactome": "R-SCE-109864", "name": "Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764616" ], "products": [ "species_10764578", "species_10764614" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "P06784", "YDL159W", "YDL159W", "YBL016W" ] }, "reaction_10788776": { "compartment": "compartment_70101", "id": "reaction_10788776", "reactome": "R-SCE-9635739", "name": "PTPN7 dephosphorylates p-T,Y-MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788755", "species_29356" ], "products": [ "species_10788773", "species_29372" ], "modifiers": [ [ "species_10788755", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "P25044", "YDL230W", "Q00772", "YHR030C", "P29461", "YOR208W", "P40048", "YER075C", "P14681", "YGR040W", "P16892", "YBL016W", "P25044", "YDL230W", "Q00772", "YHR030C", "P29461", "YOR208W", "P40048", "YER075C", "P14681", "YGR040W", "P16892", "YBL016W", "P25044", "YDL230W", "Q00772", "YHR030C", "P29461", "YOR208W", "P40048", "YER075C", "P14681", "YGR040W" ] }, "reaction_10778883": { "compartment": "compartment_70101", "id": "reaction_10778883", "reactome": "R-SCE-5675376", "name": "Cytosolic DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778780", "species_29356" ], "products": [ "species_10778842", "species_29372" ], "modifiers": [ [ "species_10778880", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P40479", "YIL113W", "P38590", "YNL053W" ] }, "reaction_10778786": { "compartment": "compartment_7660", "id": "reaction_10778786", "reactome": "R-SCE-5674387", "name": "Phosphorylated MAPKs translocate into the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778780" ], "products": [ "species_10778784" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10778836": { "compartment": "compartment_7660", "id": "reaction_10778836", "reactome": "R-SCE-5675373", "name": "Nuclear DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10778784" ], "products": [ "species_113550", "species_10778795" ], "modifiers": [ [ "species_10778833", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P40479", "YIL113W", "P38590", "YNL053W" ] }, "reaction_10788930": { "compartment": "compartment_876", "id": "reaction_10788930", "reactome": "R-SCE-9647991", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647934", "species_10767735" ], "products": [ "species_10788928" ], "modifiers": [], "additional_components": [ "Q12354", "YLR118C", "species_9647934", "Q12354", "YLR118C" ] }, "reaction_10778776": { "compartment": "compartment_20699", "id": "reaction_10778776", "reactome": "R-SCE-5674373", "name": "MAP2Ks phosphorylate MAPK at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778771", "species_113592" ], "products": [ "species_29370", "species_10778773" ], "modifiers": [ [ "species_10778771", "catalyst" ] ], "additional_components": [ "P06784", "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "P06784", "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10788926": { "compartment": "compartment_70101", "id": "reaction_10788926", "reactome": "R-SCE-9647987", "name": "FNTB inhibitors bind FNTA:FNTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9653479", "species_10788922" ], "products": [ "species_10788924" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=6531", "LigandDisplayForward?ligandId=8025", "LigandDisplayForward?ligandId=8024", "pubchem.compound:216453", "LigandDisplayForward?ligandId=8028", "LigandDisplayForward?ligandId=8026", "LigandDisplayForward?ligandId=8030", "P29703", "YKL019W", "P22007", "YDL090C", "LigandDisplayForward?ligandId=6531", "LigandDisplayForward?ligandId=8025", "P29703", "YKL019W", "LigandDisplayForward?ligandId=8024", "pubchem.compound:216453", "LigandDisplayForward?ligandId=8028", "LigandDisplayForward?ligandId=8026", "P22007", "YDL090C", "LigandDisplayForward?ligandId=8030" ] }, "reaction_10788778": { "compartment": "compartment_70101", "id": "reaction_10788778", "reactome": "R-SCE-9635743", "name": "PTPN7 binds p-T,Y-MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775862", "species_10788753" ], "products": [ "species_10788755" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P25044", "YDL230W", "P29461", "YOR208W", "P40048", "YER075C", "P16892", "YBL016W", "P25044", "YDL230W", "Q00772", "YHR030C", "P29461", "YOR208W", "P40048", "YER075C", "P14681", "YGR040W" ] }, "reaction_10785442": { "compartment": "compartment_20699", "id": "reaction_10785442", "reactome": "R-SCE-8848484", "name": "PLA2s hydrolyze phospholipids at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429785", "species_29356" ], "products": [ "species_6814303", "species_8848483" ], "modifiers": [ [ "species_10769964", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10785464": { "compartment": "compartment_20699", "id": "reaction_10785464", "reactome": "R-SCE-8849345", "name": "LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848483", "species_548819" ], "products": [ "species_76194", "species_429785" ], "modifiers": [ [ "species_10785461", "catalyst" ] ], "additional_components": [ "YOR298W" ] }, "reaction_10785255": { "compartment": "compartment_263163", "id": "reaction_10785255", "reactome": "R-SCE-6814676", "name": "SNAPs and NSF hexamer bind cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10785251" ], "products": [ "species_10785253" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "Q03322", "YDR468C", "P33328", "YOR327C", "Q04338", "YMR197C", "Q08144", "YOL018C", "Q03322", "YDR468C", "P33328", "YOR327C", "P18759", "YBR080C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P32602", "YBL050W" ] }, "reaction_10785195": { "compartment": "compartment_263163", "id": "reaction_10785195", "reactome": "R-SCE-6814088", "name": "SYS1 binds AcM-ARFRP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785165", "species_10785193" ], "products": [ "species_10785173" ], "modifiers": [], "additional_components": [ "YJL004C", "Q02804", "ARL3", "species_29438", "Q02804", "ARL3", "P41544", "YJL004C", "species_29438" ] }, "reaction_10785206": { "compartment": "compartment_263163", "id": "reaction_10785206", "reactome": "R-SCE-6814091", "name": "ARL1 recruits TGN Golgin homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785202", "species_10785187" ], "products": [ "species_10785204" ], "modifiers": [], "additional_components": [ "P47166", "YJR134C", "Q02804", "ARL3", "P38116", "YBR164C", "P41544", "YJL004C", "species_29438", "Q02804", "ARL3", "P38116", "YBR164C", "P47166", "YJR134C", "P41544", "YJL004C", "species_29438" ] }, "reaction_10785104": { "compartment": "compartment_263163", "id": "reaction_10785104", "reactome": "R-SCE-6811428", "name": "RIC1:RGP1 recruits RAB6:GDP to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785096", "species_10785084" ], "products": [ "species_10785102" ], "modifiers": [], "additional_components": [ "P16664", "YDR137W", "P40395", "YLR039C", "species_29420", "Q99260", "YLR262C", "species_29420", "P16664", "YDR137W", "Q99260", "YLR262C", "P40395", "YLR039C" ] }, "reaction_10785314": { "compartment": "compartment_263163", "id": "reaction_10785314", "reactome": "R-SCE-6814684", "name": "cis-SNARE binds SNAPs and NSF hexamer at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10785310" ], "products": [ "species_10785312" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "P31377", "YAL014C", "Q03322", "YDR468C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P31377", "YAL014C", "Q03322", "YDR468C", "P18759", "YBR080C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P32602", "YBL050W" ] }, "reaction_10785111": { "compartment": "compartment_263163", "id": "reaction_10785111", "reactome": "R-SCE-6811429", "name": "RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10785102" ], "products": [ "species_10785108", "species_29420" ], "modifiers": [ [ "species_10785102", "catalyst" ] ], "additional_components": [ "species_29420", "P16664", "YDR137W", "Q99260", "YLR262C", "P40395", "YLR039C", "P16664", "YDR137W", "Q99260", "YLR262C", "species_29438", "P40395", "YLR039C", "species_29420", "P16664", "YDR137W", "Q99260", "YLR262C", "P40395", "YLR039C" ] }, "reaction_10785189": { "compartment": "compartment_263163", "id": "reaction_10785189", "reactome": "R-SCE-6814086", "name": "ARFRP1 recruits ARL1 to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785173", "species_10785181" ], "products": [ "species_10785187" ], "modifiers": [], "additional_components": [ "Q02804", "ARL3", "P41544", "YJL004C", "species_29438", "P38116", "YBR164C", "species_29438", "Q02804", "ARL3", "P38116", "YBR164C", "P41544", "YJL004C", "species_29438" ] }, "reaction_10785258": { "compartment": "compartment_263163", "id": "reaction_10785258", "reactome": "R-SCE-6814678", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10785253" ], "products": [ "species_29370", "species_10785249", "species_10785245", "species_10769994", "species_10781444", "species_10785247", "species_10785240" ], "modifiers": [ [ "species_10785253", "catalyst" ] ], "additional_components": [ "Q03322", "YDR468C", "P33328", "YOR327C", "P18759", "YBR080C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P32602", "YBL050W", "YOR327C", "YOL018C", "YBL050W", "P18759", "YBR080C", "YMR197C", "YDR468C", "Q03322", "YDR468C", "P33328", "YOR327C", "P18759", "YBR080C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P32602", "YBL050W" ] }, "reaction_10768386": { "compartment": "compartment_70101", "id": "reaction_10768386", "reactome": "R-SCE-350769", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10768358" ], "products": [ "species_10768366", "species_29420" ], "modifiers": [ [ "species_10768383", "catalyst" ] ], "additional_components": [ "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "P11076", "YDL192W", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C" ] }, "reaction_10768579": { "compartment": "compartment_70101", "id": "reaction_10768579", "reactome": "R-SCE-376357", "name": "Vamp7 associated Lysosome to Plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768561", "species_10768567", "species_10768572" ], "products": [ "species_10768561", "species_10768567", "species_10768574" ], "modifiers": [ [ "species_10768576", "catalyst" ] ], "additional_components": [ "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "YLR093C", "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "YLR093C", "P40357", "YGR009C", "Q12255", "YLR093C", "P32867", "YPL232W", "Q04359", "YMR017W", "P39926", "YMR183C" ] }, "reaction_10768619": { "compartment": "compartment_876", "id": "reaction_10768619", "reactome": "R-SCE-376369", "name": "Vamp2 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768561", "species_10768567", "species_10768608" ], "products": [ "species_10768561", "species_10768567", "species_10768614" ], "modifiers": [ [ "species_10768616", "catalyst" ] ], "additional_components": [ "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "P33328", "YOR327C", "P31109", "YAL030W", "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "P33328", "YOR327C", "P31109", "YAL030W", "P40357", "YGR009C", "P32867", "YPL232W", "P33328", "YOR327C", "Q04359", "YMR017W", "P31109", "YAL030W", "P39926", "YMR183C" ] }, "reaction_10768602": { "compartment": "compartment_70101", "id": "reaction_10768602", "reactome": "R-SCE-376364", "name": "Vamp8 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768591", "species_10768561", "species_10768567" ], "products": [ "species_10768561", "species_10768597", "species_10768567" ], "modifiers": [ [ "species_10768599", "catalyst" ] ], "additional_components": [ "P33328", "YOR327C", "P31109", "YAL030W", "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "P40357", "YGR009C", "Q04359", "YMR017W", "P33328", "YOR327C", "P31109", "YAL030W", "P32867", "YPL232W", "P39926", "YMR183C", "P40357", "YGR009C", "P32867", "YPL232W", "P33328", "YOR327C", "Q04359", "YMR017W", "P31109", "YAL030W", "P39926", "YMR183C" ] }, "reaction_10776489": { "compartment": "compartment_7660", "id": "reaction_10776489", "reactome": "R-SCE-4411373", "name": "NLK translocates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776483" ], "products": [ "species_10776487" ], "modifiers": [], "additional_components": [ "P41808", "YPR054W", "P41808", "YPR054W" ] }, "reaction_10776538": { "compartment": "compartment_70101", "id": "reaction_10776538", "reactome": "R-SCE-4551465", "name": "Translocation of NFATC1:CaN:CaM to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776532" ], "products": [ "species_10776536" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C", "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C" ] }, "reaction_10771589": { "compartment": "compartment_70101", "id": "reaction_10771589", "reactome": "R-SCE-917700", "name": "MVB Vesicle Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771585", "species_10771366" ], "products": [ "species_10771444", "species_10771583" ], "modifiers": [], "additional_components": [ "Q06696", "YLR417W", "Q12483", "YPL002C", "P05759", "RPS31", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P47142", "YJR102C", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "Q04272", "YMR077C", "P36095", "YKL041W", "P05759", "RPS31", "P39929", "YLR025W", "Q03390", "YDR486C", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P36108", "YKL002W", "Q04272", "YMR077C", "Q06696", "YLR417W", "Q12483", "YPL002C", "P47142", "YJR102C" ] }, "reaction_10771539": { "compartment": "compartment_74700", "id": "reaction_10771539", "reactome": "R-SCE-917693", "name": "ESCRT Disassembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10771444" ], "products": [ "species_10771364", "species_29370", "species_10771520", "species_10771359", "species_10771350", "species_29372", "species_10771345", "species_10771340" ], "modifiers": [ [ "species_10771536", "catalyst" ] ], "additional_components": [ "P36095", "YKL041W", "P05759", "RPS31", "P39929", "YLR025W", "Q03390", "YDR486C", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P36108", "YKL002W", "Q04272", "YMR077C", "YDR486C", "P05759", "RPS31", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YMR077C", "YLR025W", "YKL041W", "YKL002W", "Q06263", "YLR181C", "Q03390", "YDR486C", "P52917", "YPR173C" ] }, "reaction_10771587": { "compartment": "compartment_70101", "id": "reaction_10771587", "reactome": "R-SCE-917696", "name": "Cargo Sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771566", "species_10771583" ], "products": [ "species_10771585", "species_10771564" ], "modifiers": [], "additional_components": [ "Q02767", "YPL065W", "P05759", "RPS31", "Q99176", "YLR119W", "P25604", "YCL008C", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q06696", "YLR417W", "Q12483", "YPL002C", "P47142", "YJR102C", "Q06696", "YLR417W", "Q12483", "YPL002C", "P05759", "RPS31", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P47142", "YJR102C", "Q02767", "YPL065W", "Q99176", "YLR119W", "P25604", "YCL008C" ] }, "reaction_10772483": { "compartment": "compartment_70101", "id": "reaction_10772483", "reactome": "R-SCE-984606", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772463" ], "products": [ "species_10772465" ], "modifiers": [], "additional_components": [ "YEL061C", "P27895", "YEL061C" ] }, "reaction_10774270": { "compartment": "compartment_70101", "id": "reaction_10774270", "reactome": "R-SCE-2219524", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767662", "species_179856" ], "products": [ "species_10774268" ], "modifiers": [], "additional_components": [ "YOL100W", "Q12236", "YOL100W", "species_179856" ] }, "reaction_10785347": { "compartment": "compartment_20699", "id": "reaction_10785347", "reactome": "R-SCE-8847637", "name": "NSF and SNAPs bind the cis-SNARE at the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10785343" ], "products": [ "species_10785345" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P43682", "YKL006C-A", "P38736", "YHL031C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W" ] }, "reaction_10785368": { "compartment": "compartment_20699", "id": "reaction_10785368", "reactome": "R-SCE-8847875", "name": "ARF1:GTP binds Golgin TRIP11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785364", "species_10773521" ], "products": [ "species_10785366" ], "modifiers": [], "additional_components": [ "Q12234", "YOR216C", "P11491", "YDR481C", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996", "Q12234", "YOR216C", "P11491", "YDR481C", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10785424": { "compartment": "compartment_20699", "id": "reaction_10785424", "reactome": "R-SCE-8847880", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785394", "species_10773521" ], "products": [ "species_10785422" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "Q06836", "YPR095C", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10785431": { "compartment": "compartment_20699", "id": "reaction_10785431", "reactome": "R-SCE-8847883", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785422" ], "products": [ "species_10785428" ], "modifiers": [ [ "species_10785422", "catalyst" ] ], "additional_components": [ "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "Q06836", "YPR095C", "P19146", "YDL137W", "CHEBI:15996", "species_29420", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "Q06836", "YPR095C", "P19146", "YDL137W", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "Q06836", "YPR095C", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10785350": { "compartment": "compartment_20699", "id": "reaction_10785350", "reactome": "R-SCE-8847638", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10785345" ], "products": [ "species_10784697", "species_29370", "species_10784688", "species_10784699", "species_10769994", "species_10781444", "species_10784683" ], "modifiers": [ [ "species_10785345", "catalyst" ] ], "additional_components": [ "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W", "P22804", "YIL004C", "P43682", "YKL006C-A", "YHL031C", "YLR026C", "YBL050W", "P18759", "YBR080C", "YKL196C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W" ] }, "reaction_10772494": { "compartment": "compartment_17906", "id": "reaction_10772494", "reactome": "R-SCE-992703", "name": "Mitofusins trans-interact linking mitochondria prior to fusion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772488" ], "products": [ "species_10772492" ], "modifiers": [], "additional_components": [ "YBR179C", "P38297", "YBR179C" ] }, "reaction_10772555": { "compartment": "compartment_74700", "id": "reaction_10772555", "reactome": "R-SCE-1011576", "name": "EHD proteins interact with Rabenosyn-5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772546", "species_10772551" ], "products": [ "species_10772553" ], "modifiers": [], "additional_components": [ "P32790", "YBL007C", "P36115", "YKR019C", "YDR323C", "P32790", "YBL007C", "P36115", "YKR019C", "P32609", "YDR323C" ] }, "reaction_10772520": { "compartment": "compartment_5460", "id": "reaction_10772520", "reactome": "R-SCE-1008248", "name": "Adenylate Kinase 3 is a GTP-AMP phosphotransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159448", "species_113573" ], "products": [ "species_113525", "species_113581" ], "modifiers": [ [ "species_10772517", "catalyst" ] ], "additional_components": [ "YER170W" ] }, "reaction_10772572": { "compartment": "compartment_70101", "id": "reaction_10772572", "reactome": "R-SCE-1011598", "name": "DOCKs bind to RhoGEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768888", "species_10772560" ], "products": [ "species_10772570" ], "modifiers": [], "additional_components": [ "YLR229C", "YLR422W", "Q06409", "YLR422W", "P19073", "YLR229C" ] }, "reaction_10772503": { "compartment": "compartment_70101", "id": "reaction_10772503", "reactome": "R-SCE-992708", "name": "Dual-specific AKAPs bind type I and II PKA regulatory subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764953", "species_10772499" ], "products": [ "species_10772501" ], "modifiers": [], "additional_components": [ "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "YOR301W", "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "Q08760", "YOR301W", "P06244", "YJL164C" ] }, "reaction_10771252": { "compartment": "compartment_70101", "id": "reaction_10771252", "reactome": "R-SCE-879459", "name": "F-actin capping protein is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771243", "species_10771248" ], "products": [ "species_10771250" ], "modifiers": [], "additional_components": [ "YKL007W", "YIL034C", "P28495", "YKL007W", "P13517", "YIL034C" ] } }, "motif_reaction_dictionary": { "reaction_10760997": { "compartment": "compartment_7660", "id": "reaction_10760997", "reactome": "R-SCE-69173", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68452" ], "products": [ "species_69172" ], "modifiers": [ [ "species_10760994", "catalyst" ] ], "additional_components": [ "YDL164C" ] }, "reaction_10760965": { "compartment": "compartment_7660", "id": "reaction_10760965", "reactome": "R-SCE-69127", "name": "Formation of the Flap Intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760961" ], "products": [ "species_10760963" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P15436", "POL3", "P10363", "YIR008C", "P46957", "YJR006W", "P15873", "YBR088C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P15436", "POL3", "P10363", "YIR008C", "P46957", "YJR006W", "P15873", "YBR088C", "P20457", "YKL045W" ] }, "reaction_10760977": { "compartment": "compartment_7660", "id": "reaction_10760977", "reactome": "R-SCE-69142", "name": "Recruitment of Dna2 endonuclease", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760969", "species_10760973" ], "products": [ "species_10760975" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P15436", "POL3", "P22336", "YAR007C", "P10363", "YIR008C", "P46957", "YJR006W", "P26754", "YNL312W", "P15873", "YBR088C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P15436", "POL3", "P22336", "YAR007C", "P10363", "YIR008C", "P46957", "YJR006W", "P26754", "YNL312W", "P15873", "YBR088C", "P38859", "DNA2", "P20457", "YKL045W" ] }, "reaction_10760989": { "compartment": "compartment_7660", "id": "reaction_10760989", "reactome": "R-SCE-69152", "name": "Removal of remaining Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760979" ], "products": [ "species_10760981" ], "modifiers": [ [ "species_10760986", "catalyst" ] ], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P15436", "POL3", "P10363", "YIR008C", "P46957", "YJR006W", "P15873", "YBR088C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P15436", "POL3", "P10363", "YIR008C", "P46957", "YJR006W", "P15873", "YBR088C", "P20457", "YKL045W", "YKL113C" ] }, "reaction_10763788": { "compartment": "compartment_350", "id": "reaction_10763788", "reactome": "R-SCE-74986", "name": "Elongation of pre-rRNA transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_74985" ], "products": [ "species_74985" ], "modifiers": [ [ "species_10763299", "catalyst" ], [ "species_10763786", "catalyst" ] ], "additional_components": [ "Q01080", "YNL248C", "P20434", "RPB5", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P46669", "YOR340C", "P07703", "RPC40", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "Q04673", "YLR005W", "P10964", "YOR341W", "Q00578", "YIL143C", "P20436", "RPB8", "Q03290", "YDR460W", "Q12004", "YPR056W", "P40992", "YJL025W", "Q02939", "YPL122C", "P32529", "YJR063W", "P40422", "RPC10", "P22139", "RPB10", "P22138", "YPR010C", "P06839", "RAD3", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10763301": { "compartment": "compartment_7660", "id": "reaction_10763301", "reactome": "R-SCE-73769", "name": "Loss of Rrn3 from RNA Polymerase I promoter escape complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763295" ], "products": [ "species_10763299", "species_10763212" ], "modifiers": [], "additional_components": [ "Q01080", "YNL248C", "P20434", "RPB5", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P46669", "YOR340C", "P07703", "RPC40", "P32776", "YDR311W", "P36070", "YKL125W", "P06242", "YDL108W", "P13393", "SPT15", "Q04673", "YLR005W", "P10964", "YOR341W", "Q00578", "YIL143C", "P20436", "RPB8", "Q03290", "YDR460W", "Q12004", "YPR056W", "P40992", "YJL025W", "Q02939", "YPL122C", "P32529", "YJR063W", "P40422", "RPC10", "P22139", "RPB10", "P22138", "YPR010C", "P06839", "RAD3", "Q01080", "YNL248C", "P20434", "RPB5", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P46669", "YOR340C", "P07703", "RPC40", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "Q04673", "YLR005W", "P10964", "YOR341W", "Q00578", "YIL143C", "P20436", "RPB8", "Q03290", "YDR460W", "Q12004", "YPR056W", "P40992", "YJL025W", "Q02939", "YPL122C", "P32529", "YJR063W", "P40422", "RPC10", "P22139", "RPB10", "P22138", "YPR010C", "P06839", "RAD3", "YKL125W" ] }, "reaction_10763216": { "compartment": "compartment_7660", "id": "reaction_10763216", "reactome": "R-SCE-73757", "name": "Binding of RRN3 to RNA Polymerase I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763207", "species_10763212" ], "products": [ "species_10763214" ], "modifiers": [], "additional_components": [ "P10964", "YOR341W", "Q01080", "YNL248C", "P20434", "RPB5", "P20436", "RPB8", "P20435", "RPO26", "P32529", "YJR063W", "P40422", "RPC10", "P46669", "YOR340C", "P07703", "RPC40", "P22139", "RPB10", "P22138", "YPR010C", "YKL125W", "P10964", "YOR341W", "Q01080", "YNL248C", "P20434", "RPB5", "P20436", "RPB8", "P20435", "RPO26", "P32529", "YJR063W", "P40422", "RPC10", "P46669", "YOR340C", "P07703", "RPC40", "P22139", "RPB10", "P22138", "YPR010C", "P36070", "YKL125W" ] }, "reaction_10760927": { "compartment": "compartment_7660", "id": "reaction_10760927", "reactome": "R-SCE-69053", "name": "RFC binding displaces Pol Alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760830", "species_10760923" ], "products": [ "species_10760925" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P40348", "YJR068W", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "P38121", "YBL035C", "P13382", "YNL102W", "P40348", "YJR068W", "P10363", "YIR008C", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P20457", "YKL045W", "P38629", "YNL290W" ] }, "reaction_10760938": { "compartment": "compartment_7660", "id": "reaction_10760938", "reactome": "R-SCE-69063", "name": "Loading of PCNA - Sliding Clamp Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10760925", "species_10760934" ], "products": [ "species_113582", "species_10760936" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P40348", "YJR068W", "P10363", "YIR008C", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P20457", "YKL045W", "P38629", "YNL290W", "P15873", "YBR088C", "P38121", "YBL035C", "P13382", "YNL102W", "P40348", "YJR068W", "P10363", "YIR008C", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P20457", "YKL045W", "P38629", "YNL290W" ] }, "reaction_10760942": { "compartment": "compartment_7660", "id": "reaction_10760942", "reactome": "R-SCE-69068", "name": "RFC dissociates after sliding clamp formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760936" ], "products": [ "species_10760940", "species_10760923" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P40348", "YJR068W", "P10363", "YIR008C", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P20457", "YKL045W", "P38629", "YNL290W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P15873", "YBR088C", "P20457", "YKL045W", "P40348", "YJR068W", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W" ] }, "reaction_10773145": { "compartment": "compartment_12045", "id": "reaction_10773145", "reactome": "R-SCE-1482856", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[5]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10773142", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10773130": { "compartment": "compartment_12045", "id": "reaction_10773130", "reactome": "R-SCE-1482827", "name": "PC is hydrolyzed to 2-acyl LPC by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_975614", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10772925": { "compartment": "compartment_12045", "id": "reaction_10772925", "reactome": "R-SCE-1482533", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_1500578" ], "products": [ "species_76194", "species_426925" ], "modifiers": [ [ "species_10772920", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10773122": { "compartment": "compartment_12045", "id": "reaction_10773122", "reactome": "R-SCE-1482816", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10772968": { "compartment": "compartment_12045", "id": "reaction_10772968", "reactome": "R-SCE-1482547", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_1500578" ], "products": [ "species_76194", "species_426925" ], "modifiers": [ [ "species_10772920", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10773151": { "compartment": "compartment_12045", "id": "reaction_10773151", "reactome": "R-SCE-1482862", "name": "PC is hydrolysed to 2-acyl LPC by PLA2[7]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_975614", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10774233": { "compartment": "compartment_7660", "id": "reaction_10774233", "reactome": "R-SCE-2172678", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10774226", "species_113685" ], "products": [ "species_159942", "species_10774230", "species_159939", "species_29478" ], "modifiers": [ [ "species_10774226", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "species_111793", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "species_111793", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "species_111793", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10777844": { "compartment": "compartment_876", "id": "reaction_10777844", "reactome": "R-SCE-5607734", "name": "PKC-delta translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777274", "species_112275" ], "products": [ "species_10777842" ], "modifiers": [], "additional_components": [ "YBL105C", "species_112275", "P24583", "YBL105C" ] }, "reaction_10774717": { "compartment": "compartment_70101", "id": "reaction_10774717", "reactome": "R-SCE-2730867", "name": "Translocation of CaN:CaM:NFAT to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774691" ], "products": [ "species_10774715" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C", "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C" ] }, "reaction_10777848": { "compartment": "compartment_876", "id": "reaction_10777848", "reactome": "R-SCE-5607746", "name": "PKC-delta is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777842" ], "products": [ "species_10777846" ], "modifiers": [], "additional_components": [ "species_112275", "P24583", "YBL105C", "species_112275", "P24583", "YBL105C" ] }, "reaction_10774719": { "compartment": "compartment_70101", "id": "reaction_10774719", "reactome": "R-SCE-2730872", "name": "Activation of Calcineurin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767628", "species_74016", "species_10773995" ], "products": [ "species_10774687" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_74016", "species_158417", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C", "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C" ] }, "reaction_10777840": { "compartment": "compartment_70101", "id": "reaction_10777840", "reactome": "R-SCE-5607721", "name": "Activation of NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769138" ], "products": [ "species_10769138" ], "modifiers": [], "additional_components": [ "YCR073C", "YCR073C" ] }, "reaction_10774165": { "compartment": "compartment_70101", "id": "reaction_10774165", "reactome": "R-SCE-2162078", "name": "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161185", "species_29360" ], "products": [ "species_70106", "species_73473", "species_2162081" ], "modifiers": [ [ "species_10762111", "catalyst" ] ], "additional_components": [ "species_158417", "P32771", "YDL168W" ] }, "reaction_10760457": { "compartment": "compartment_7660", "id": "reaction_10760457", "reactome": "R-SCE-68944", "name": "Orc1 is phosphorylated by cyclin A/CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760396", "species_29358" ], "products": [ "species_113582", "species_10760408", "species_10760404" ], "modifiers": [ [ "species_10760454", "catalyst" ] ], "additional_components": [ "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P32833", "ORC2", "P54791", "ORC4", "P30665", "MCM4", "P54784", "phospho-ORC1", "P09119", "CDC6", "P53091", "MCM6", "P50874", "ORC5", "P29496", "MCM5", "P54790", "ORC3", "P24279", "MCM3", "P29469", "MCM2", "P32833", "ORC2", "P38132", "MCM7", "P54791", "ORC4", "P30665", "MCM4", "P09119", "CDC6", "P53091", "MCM6", "P50874", "ORC5", "P29496", "MCM5", "P54790", "ORC3", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760888": { "compartment": "compartment_7660", "id": "reaction_10760888", "reactome": "R-SCE-69006", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760843" ], "products": [ "species_10760886" ], "modifiers": [], "additional_components": [] }, "reaction_10760562": { "compartment": "compartment_7660", "id": "reaction_10760562", "reactome": "R-SCE-68946", "name": "Phosphorylated Orc1 is ubiquitinated while still associated with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760404", "species_10760537" ], "products": [ "species_10760540" ], "modifiers": [ [ "species_10760559", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W" ] }, "reaction_10760828": { "compartment": "compartment_70101", "id": "reaction_10760828", "reactome": "R-SCE-68948", "name": "Ubiquitinated Orc1 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760564" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10760566": { "compartment": "compartment_7660", "id": "reaction_10760566", "reactome": "R-SCE-68947", "name": "Ubiquitinated Orc1 enters the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760540" ], "products": [ "species_10760564" ], "modifiers": [], "additional_components": [] }, "reaction_10760896": { "compartment": "compartment_7660", "id": "reaction_10760896", "reactome": "R-SCE-69019", "name": "Mcm4,6,7 trimer forms and associates with the replication fork", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760363" ], "products": [ "species_10760359", "species_10760355", "species_10760349", "species_10760335" ], "modifiers": [], "additional_components": [ "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29496", "MCM5", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6" ] }, "reaction_10760884": { "compartment": "compartment_7660", "id": "reaction_10760884", "reactome": "R-SCE-69005", "name": "Cdc6 protein is phosphorylated by CDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10760214" ], "products": [ "species_113582", "species_10760843" ], "modifiers": [ [ "species_10760881", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760894": { "compartment": "compartment_70101", "id": "reaction_10760894", "reactome": "R-SCE-69016", "name": "Ubiquitinated Cdc6 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760892" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P09119", "CDC6", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10765258": { "compartment": "compartment_70101", "id": "reaction_10765258", "reactome": "R-SCE-114553", "name": "Activation of conventional Protein Kinase C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_33625", "species_10765240", "species_114519" ], "products": [ "species_10765256" ], "modifiers": [ [ "species_114519", "catalyst" ] ], "additional_components": [ "YBL105C", "species_33625", "P24583", "YBL105C", "species_74016", "species_6797635" ] }, "reaction_10769689": { "compartment": "compartment_70101", "id": "reaction_10769689", "reactome": "R-SCE-426043", "name": "2-AG hydrolysis to arachidonate by MAGL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426030", "species_29356" ], "products": [ "species_70106", "species_76116", "species_422506" ], "modifiers": [ [ "species_10769686", "catalyst" ] ], "additional_components": [ "YKL094W" ] }, "reaction_10765269": { "compartment": "compartment_70101", "id": "reaction_10765269", "reactome": "R-SCE-114683", "name": "Phosphorylation of Platelet Sec-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765263", "species_113592" ], "products": [ "species_29370", "species_10765266" ], "modifiers": [ [ "species_10765256", "catalyst" ] ], "additional_components": [ "YDR164C", "YDR164C", "species_33625", "P24583", "YBL105C", "species_74016", "species_6797635" ] }, "reaction_10771032": { "compartment": "compartment_70101", "id": "reaction_10771032", "reactome": "R-SCE-482772", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771010" ], "products": [ "species_10771030" ], "modifiers": [], "additional_components": [ "P60010", "YFL039C", "P06787", "YBR109C", "P09734", "YML124C", "Q12311", "YPR031W", "P46680", "YMR092C", "P30619", "YDR164C", "P00445", "SOD1", "P09733", "YML085C", "P60010", "YFL039C", "P06787", "YBR109C", "P09734", "YML124C", "Q12311", "YPR031W", "P46680", "YMR092C", "P30619", "YDR164C", "P00445", "SOD1", "P09733", "YML085C" ] }, "reaction_10769954": { "compartment": "compartment_70101", "id": "reaction_10769954", "reactome": "R-SCE-428941", "name": "P2Y purinoceptor 1 activates MAP kinase p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10769952" ], "products": [ "species_29370", "species_10766455" ], "modifiers": [ [ "species_10764870", "catalyst" ] ], "additional_components": [ "YLR113W", "YLR113W", "species_29438", "P10823", "YER020W" ] }, "reaction_10768515": { "compartment": "compartment_70101", "id": "reaction_10768515", "reactome": "R-SCE-354173", "name": "Activation of Rap1 by cytosolic GEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10768483" ], "products": [ "species_10768481", "species_29420" ], "modifiers": [ [ "species_10768512", "catalyst" ] ], "additional_components": [ "species_29420", "P13856", "YGR152C", "species_29438", "P13856", "YGR152C", "P04821", "YLR310C", "species_74016", "species_6797635", "P07866", "YAL024C", "P25300", "YCR038C" ] }, "reaction_10765291": { "compartment": "compartment_70101", "id": "reaction_10765291", "reactome": "R-SCE-114684", "name": "Phosphorylation of Syntaxin-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765281", "species_113592" ], "products": [ "species_29370", "species_10765289" ], "modifiers": [ [ "species_10765256", "catalyst" ] ], "additional_components": [ "P32867", "YPL232W", "P39926", "YMR183C", "P32867", "YPL232W", "P39926", "YMR183C", "species_33625", "P24583", "YBL105C", "species_74016", "species_6797635" ] }, "reaction_10770963": { "compartment": "compartment_876", "id": "reaction_10770963", "reactome": "R-SCE-481009", "name": "Exocytosis of platelet dense granule content", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770957" ], "products": [ "species_10770961" ], "modifiers": [], "additional_components": [ "species_29372", "species_74016", "species_113592", "species_29370", "species_111294", "CHEBI:15996", "species_111349", "P06101", "YDR168W", "species_109496", "species_209914", "species_29420", "species_29372", "species_74016", "species_113592", "species_29370", "species_29438", "species_111294", "P06101", "YDR168W", "species_109496", "species_209914" ] }, "reaction_10769661": { "compartment": "compartment_70101", "id": "reaction_10769661", "reactome": "R-SCE-425861", "name": "Activation of Protein Kinase C novel isoforms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767110", "species_114519" ], "products": [ "species_10769659" ], "modifiers": [], "additional_components": [ "YBL105C", "P24583", "YBL105C", "species_6797635" ] }, "reaction_10770980": { "compartment": "compartment_876", "id": "reaction_10770980", "reactome": "R-SCE-481044", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770972" ], "products": [ "species_10770978" ], "modifiers": [], "additional_components": [ "P38626", "YIL043C", "P53858", "YNL233W", "P38626", "YIL043C", "P53858", "YNL233W" ] }, "reaction_10774272": { "compartment": "compartment_70101", "id": "reaction_10774272", "reactome": "R-SCE-2316429", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767662", "species_179838" ], "products": [ "species_10764515" ], "modifiers": [], "additional_components": [ "YOL100W", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10769967": { "compartment": "compartment_70101", "id": "reaction_10769967", "reactome": "R-SCE-428961", "name": "Phosphorylation of cPLA2 by MAPK p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10769964" ], "products": [ "species_29370", "species_10764905" ], "modifiers": [ [ "species_10766455", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "YLR113W" ] }, "reaction_10770950": { "compartment": "compartment_876", "id": "reaction_10770950", "reactome": "R-SCE-481007", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770940" ], "products": [ "species_10770948" ], "modifiers": [], "additional_components": [ "Q05541", "YDR288W", "Q04338", "YMR197C", "P38219", "YBR025C", "Q05541", "YDR288W", "Q04338", "YMR197C", "P38219", "YBR025C" ] }, "reaction_10781550": { "compartment": "compartment_876", "id": "reaction_10781550", "reactome": "R-SCE-5694462", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694509", "species_29356" ], "products": [ "species_70106", "species_76116", "species_422506" ], "modifiers": [ [ "species_10781547", "catalyst" ] ], "additional_components": [ "YBR204C" ] }, "reaction_10769989": { "compartment": "compartment_114584", "id": "reaction_10769989", "reactome": "R-SCE-429157", "name": "ABCC4 accumulation of dense granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29372", "species_114565" ], "modifiers": [ [ "species_10769986", "catalyst" ] ], "additional_components": [ "YKL209C" ] }, "reaction_10770278": { "compartment": "compartment_70101", "id": "reaction_10770278", "reactome": "R-SCE-442749", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10770270" ], "products": [ "species_113582", "species_10770275" ], "modifiers": [ [ "species_10770270", "catalyst" ] ], "additional_components": [ "P06787", "YBR109C", "P43637", "YGL179C", "species_74016", "P06787", "YBR109C", "P43637", "YGL179C", "species_74016", "P06787", "YBR109C", "P43637", "YGL179C", "species_74016" ] }, "reaction_10789297": { "compartment": "compartment_70101", "id": "reaction_10789297", "reactome": "R-SCE-9748957", "name": "GMPS dimer transforms 6TXMP to 6TGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29356", "species_9748959" ], "products": [ "species_70106", "species_9748970", "species_29404", "species_111294", "species_76577" ], "modifiers": [ [ "species_10789294", "catalyst" ] ], "additional_components": [ "P38625", "YMR217W" ] }, "reaction_10789292": { "compartment": "compartment_70101", "id": "reaction_10789292", "reactome": "R-SCE-9748949", "name": "GUK1 phosphorylates 6TGMP to 6TGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9748970", "species_113592" ], "products": [ "species_29370", "species_9748960" ], "modifiers": [ [ "species_10763306", "catalyst" ] ], "additional_components": [ "YDR454C" ] }, "reaction_10766344": { "compartment": "compartment_17957", "id": "reaction_10766344", "reactome": "R-SCE-174931", "name": "UGTs transfer GlcA from UDP-GlcA to O-centre substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174384", "species_174911" ], "products": [ "species_158602", "species_174914" ], "modifiers": [ [ "species_10765441", "catalyst" ] ], "additional_components": [ "CHEBI:16580", "CHEBI:34665", "CHEBI:15882", "species_9749790", "CHEBI:46195", "CHEBI:32649", "species_158604", "CHEBI:65137", "CHEBI:176976", "CHEBI:64681", "YLR189C" ] }, "reaction_10789324": { "compartment": "compartment_70101", "id": "reaction_10789324", "reactome": "R-SCE-9751024", "name": "SLC29A1,2 transport 6MP from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9751015" ], "products": [ "species_9748998" ], "modifiers": [ [ "species_10764480", "catalyst" ] ], "additional_components": [ "YAL022C" ] }, "reaction_10789290": { "compartment": "compartment_70101", "id": "reaction_10789290", "reactome": "R-SCE-9748945", "name": "IMPDH tetramers dehydrogenate 6TIMP to 6TXMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9748992", "species_29360", "species_29356" ], "products": [ "species_73473", "species_70106", "species_9748959" ], "modifiers": [ [ "species_10763342", "catalyst" ] ], "additional_components": [ "P38697", "YHR216W", "P50095", "YLR432W", "P50094", "YML056C" ] }, "reaction_10789337": { "compartment": "compartment_70101", "id": "reaction_10789337", "reactome": "R-SCE-9753284", "name": "ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9753629", "species_29356" ], "products": [ "species_29370", "species_9753624", "species_29372" ], "modifiers": [ [ "species_10789334", "catalyst" ] ], "additional_components": [ "CHEBI:133438", "species_9753653", "CHEBI:133066", "CHEBI:133435", "P39109", "YDR135C", "P12866", "YKL209C" ] }, "reaction_10789314": { "compartment": "compartment_17957", "id": "reaction_10789314", "reactome": "R-SCE-9749977", "name": "UGT1A6 glucuronates ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9749790", "species_174384" ], "products": [ "species_158602", "species_9749997" ], "modifiers": [ [ "species_10765443", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10789299": { "compartment": "compartment_70101", "id": "reaction_10789299", "reactome": "R-SCE-9748963", "name": "GUK1 phosphorylates 6TdGMP to 6TdGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9749031", "species_113592" ], "products": [ "species_29370", "species_9749033" ], "modifiers": [ [ "species_10763306", "catalyst" ] ], "additional_components": [ "YDR454C" ] }, "reaction_10789332": { "compartment": "compartment_70101", "id": "reaction_10789332", "reactome": "R-SCE-9753283", "name": "ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_9753559" ], "products": [ "species_29370", "species_9753562", "species_29372" ], "modifiers": [ [ "species_10789329", "catalyst" ] ], "additional_components": [ "CHEBI:32635", "species_158604", "CHEBI:32636", "CHEBI:32635", "P53049", "YGR281W", "P12866", "YKL209C" ] }, "reaction_10789327": { "compartment": "compartment_70101", "id": "reaction_10789327", "reactome": "R-SCE-9753278", "name": "ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_9753559" ], "products": [ "species_29370", "species_9753562", "species_29372" ], "modifiers": [ [ "species_10772886", "catalyst" ] ], "additional_components": [ "CHEBI:32635", "species_158604", "CHEBI:32636", "CHEBI:32635", "P14772", "YLL015W", "P39109", "YDR135C", "P32386", "YLL048C", "P38735", "YHL035C" ] }, "reaction_10789339": { "compartment": "compartment_70101", "id": "reaction_10789339", "reactome": "R-SCE-9753632", "name": "CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9753680", "species_29356" ], "products": [ "species_9753653", "species_29424" ], "modifiers": [ [ "species_10772689", "catalyst" ] ], "additional_components": [ "species_113527", "P43616", "YFR044C" ] }, "reaction_10765448": { "compartment": "compartment_70101", "id": "reaction_10765448", "reactome": "R-SCE-158546", "name": "UGTs glucuronate APAP to APAP-GlcA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158601", "species_9677362" ], "products": [ "species_110096", "species_158604" ], "modifiers": [ [ "species_10765441", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10789301": { "compartment": "compartment_70101", "id": "reaction_10789301", "reactome": "R-SCE-9748969", "name": "NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9749033" ], "products": [ "species_29370", "species_9749032" ], "modifiers": [ [ "species_10770987", "catalyst" ] ], "additional_components": [ "P36010", "YKL067W" ] }, "reaction_10789303": { "compartment": "compartment_70101", "id": "reaction_10789303", "reactome": "R-SCE-9748999", "name": "NME1:2 hexamer phosphorylates 6TGDP to 6TGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9748960" ], "products": [ "species_29370", "species_9748947" ], "modifiers": [ [ "species_10770987", "catalyst" ] ], "additional_components": [ "P36010", "YKL067W" ] }, "reaction_10789322": { "compartment": "compartment_70101", "id": "reaction_10789322", "reactome": "R-SCE-9750656", "name": "ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9750692", "species_113592", "species_29356" ], "products": [ "species_29370", "species_9750678", "species_29372" ], "modifiers": [ [ "species_10789319", "catalyst" ] ], "additional_components": [ "CHEBI:9008", "CHEBI:58044", "CHEBI:88742", "CHEBI:176976", "CHEBI:36654", "species_9749997", "CHEBI:9008", "CHEBI:58044", "CHEBI:88742", "CHEBI:176976", "CHEBI:36654", "species_9749997", "P14772", "YLL015W", "P39109", "YDR135C", "P32386", "YLL048C", "P38735", "YHL035C", "P53049", "YGR281W" ] }, "reaction_10789317": { "compartment": "compartment_70101", "id": "reaction_10789317", "reactome": "R-SCE-9750546", "name": "ABCC4 transports TPMP substrates from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9750587", "species_113592", "species_29356" ], "products": [ "species_29370", "species_9750548", "species_29372" ], "modifiers": [ [ "species_10772888", "catalyst" ] ], "additional_components": [ "species_9748992", "species_9748970", "pubchem.compound:3037883", "CHEBI:80613", "pubchem.compound:3037883", "CHEBI:2332", "YKL209C" ] }, "reaction_10789341": { "compartment": "compartment_876", "id": "reaction_10789341", "reactome": "R-SCE-9753634", "name": "GGT dimers hydrolyse APAP-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9753685", "species_29356" ], "products": [ "species_9753680", "species_29404" ], "modifiers": [ [ "species_10777790", "catalyst" ] ], "additional_components": [ "Q05902", "YLR299W" ] }, "reaction_10781056": { "compartment": "compartment_7660", "id": "reaction_10781056", "reactome": "R-SCE-5691001", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781053", "species_30555" ], "products": [ "species_10781051", "species_113541" ], "modifiers": [ [ "species_10781053", "catalyst" ] ], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W" ] }, "reaction_10779690": { "compartment": "compartment_7660", "id": "reaction_10779690", "reactome": "R-SCE-5689861", "name": "Recruitment of XPA and release of CAK ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779684", "species_10779650" ], "products": [ "species_10763257", "species_10779688" ], "modifiers": [], "additional_components": [ "Q08273", "YOL133W", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "P05759", "RPS31", "Q02939", "YPL122C", "P32628", "YEL037C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q06665", "YDR314C", "P06839", "RAD3", "YMR201C", "Q03290", "YDR460W", "P37366", "YPR025C", "P06242", "YDL108W", "Q08273", "YOL133W", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P28519", "YMR201C", "P32776", "YDR311W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q12004", "YPR056W", "P05759", "RPS31", "Q02939", "YPL122C", "P32628", "YEL037C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q06665", "YDR314C", "P06839", "RAD3" ] }, "reaction_10766961": { "compartment": "compartment_70101", "id": "reaction_10766961", "reactome": "R-SCE-196773", "name": "COASY phosphorylates DP-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196778" ], "products": [ "species_76194", "species_29370" ], "modifiers": [ [ "species_10766945", "catalyst" ] ], "additional_components": [ "YGR277C" ] }, "reaction_10766940": { "compartment": "compartment_70101", "id": "reaction_10766940", "reactome": "R-SCE-196753", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111707", "species_196786" ], "products": [ "species_196834", "species_111294", "species_76577" ], "modifiers": [ [ "species_10766937", "catalyst" ] ], "additional_components": [ "P40506", "YIL083C" ] }, "reaction_10766948": { "compartment": "compartment_70101", "id": "reaction_10766948", "reactome": "R-SCE-196754", "name": "COASY transfers an adenylyl group from ATP to PPANT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196767", "species_113592" ], "products": [ "species_196778", "species_111294" ], "modifiers": [ [ "species_10766945", "catalyst" ] ], "additional_components": [ "YGR277C" ] }, "reaction_10767291": { "compartment": "compartment_70616", "id": "reaction_10767291", "reactome": "R-SCE-199216", "name": "SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194" ], "products": [ "species_29374" ], "modifiers": [ [ "species_10767288", "catalyst" ] ], "additional_components": [ "YHR002W" ] }, "reaction_10766971": { "compartment": "compartment_70101", "id": "reaction_10766971", "reactome": "R-SCE-196840", "name": "3xPPCDC:3FMN decarboxylates PPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196834" ], "products": [ "species_196767", "species_113528" ], "modifiers": [ [ "species_10766968", "catalyst" ] ], "additional_components": [ "P36076", "YKL088W", "species_73524" ] }, "reaction_10779496": { "compartment": "compartment_7660", "id": "reaction_10779496", "reactome": "R-SCE-5686430", "name": "MUS81 binds EME1, EME2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779488", "species_10779481" ], "products": [ "species_10779494" ], "modifiers": [], "additional_components": [ "YDR386W", "YBR098W", "P38257", "YBR098W", "Q04149", "YDR386W" ] }, "reaction_10761487": { "compartment": "compartment_70101", "id": "reaction_10761487", "reactome": "R-SCE-70581", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76213", "species_29404" ], "products": [ "species_29448", "species_29406" ], "modifiers": [ [ "species_10761484", "catalyst" ] ], "additional_components": [ "P23542", "YLR027C" ] }, "reaction_10761500": { "compartment": "compartment_5460", "id": "reaction_10761500", "reactome": "R-SCE-70596", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113553" ], "products": [ "species_113552", "species_113587" ], "modifiers": [ [ "species_10761497", "catalyst" ] ], "additional_components": [ "Q01802", "YKL106W" ] }, "reaction_10761517": { "compartment": "compartment_70101", "id": "reaction_10761517", "reactome": "R-SCE-70599", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29448", "species_113592", "species_29356" ], "products": [ "species_29404", "species_29642", "species_111294", "species_76577" ], "modifiers": [ [ "species_10761514", "catalyst" ] ], "additional_components": [ "P49090", "YGR124W", "P49089", "YPR145W" ] }, "reaction_10781277": { "compartment": "compartment_876", "id": "reaction_10781277", "reactome": "R-SCE-5693783", "name": "NAALADases hydrolyse NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693762" ], "products": [ "species_29404", "species_5693772" ], "modifiers": [ [ "species_10781274", "catalyst" ] ], "additional_components": [ "Q08693", "YOR256C", "P47161", "YJR126C", "Q08919", "YPL176C" ] }, "reaction_10768525": { "compartment": "compartment_70101", "id": "reaction_10768525", "reactome": "R-SCE-372448", "name": "SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113553" ], "products": [ "species_29448", "species_113552" ], "modifiers": [ [ "species_10768520", "catalyst" ] ], "additional_components": [ "YPR021C" ] }, "reaction_10761489": { "compartment": "compartment_70101", "id": "reaction_10761489", "reactome": "R-SCE-70592", "name": "PXLP-K259-GOT1 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29448", "species_29406" ], "products": [ "species_29404", "species_76213" ], "modifiers": [ [ "species_10761484", "catalyst" ] ], "additional_components": [ "P23542", "YLR027C" ] }, "reaction_10782374": { "compartment": "compartment_7660", "id": "reaction_10782374", "reactome": "R-SCE-6791222", "name": "21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782324" ], "products": [ "species_10782340" ], "modifiers": [ [ "species_10782371", "catalyst" ], [ "species_10782359", "catalyst" ], [ "species_10782077", "catalyst" ], [ "species_10782345", "catalyst" ] ], "additional_components": [ "Q04177", "UTP5", "P53941", "IMP4", "Q02354", "UTP6", "P25368", "RRP7", "Q04217", "ECM16", "P06367", "RPS14A", "P25443", "RPS2", "P40498", "UTP25", "Q05498", "FCF1", "P35194", "UTP20", "Q99207", "NOP14", "P40362", "UTP18", "P34247", "UTP11", "Q04305", "UTP15", "Q06512", "NOC4", "P40055", "UTP7", "Q12220", "DIP2", "P33750", "SOF1", "Q08965", "BMS1", "P39990", "SNU13", "P47083", "MPP10", "Q06287", "EMG1", "P38719", "DBP8", "Q05022", "RRP5", "P45818", "ROK1", "P38712", "RRP3", "P05755", "RPS9B", "Q02931", "NAN1", "P42945", "UTP10", "Q08096", "RCL1", "Q12136", "SAS10", "Q06506", "RRP9", "P0CX37", "RPS6A", "Q06679", "UTP4", "P26786", "RPS7A", "P25586", "KRR1", "P15646", "NOP1", "Q05946", "UTP13", "Q12460", "NOP56", "Q06078", "UTP21", "P25635", "PWP2", "P53254", "UTP22", "Q04500", "UTP14", "P32899", "IMP3", "Q12481", "RRP36", "Q12499", "NOP58", "P0CX38", "RPS6B", "P39516", "RPS14B", "Q04177", "UTP5", "P53941", "IMP4", "Q02354", "UTP6", "P25368", "RRP7", "Q04217", "ECM16", "P06367", "RPS14A", "P25443", "RPS2", "P40498", "UTP25", "Q05498", "FCF1", "P35194", "UTP20", "Q99207", "NOP14", "P40362", "UTP18", "P34247", "UTP11", "Q04305", "UTP15", "Q06512", "NOC4", "P40055", "UTP7", "Q12220", "DIP2", "P33750", "SOF1", "Q08965", "BMS1", "P39990", "SNU13", "P47083", "MPP10", "Q06287", "EMG1", "P38719", "DBP8", "Q05022", "RRP5", "P45818", "ROK1", "P38712", "RRP3", "P05755", "RPS9B", "Q02931", "NAN1", "P42945", "UTP10", "Q08096", "RCL1", "Q12136", "SAS10", "Q06506", "RRP9", "P0CX37", "RPS6A", "Q06679", "UTP4", "P26786", "RPS7A", "P25586", "KRR1", "P15646", "NOP1", "Q05946", "UTP13", "Q12460", "NOP56", "Q06078", "UTP21", "P25635", "PWP2", "P53254", "UTP22", "Q04500", "UTP14", "P32899", "IMP3", "Q12481", "RRP36", "Q12499", "NOP58", "P0CX38", "RPS6B", "P39516", "RPS14B", "P38801", "YHR081W", "Q12149", "YOR001W", "P53859", "CSL4", "Q08285", "RRP40", "P53256", "RRP46", "Q12277", "RRP42", "P48240", "MTR3", "P38792", "RRP4", "P46948", "SKI6", "P47047", "YJL050W", "Q05636", "RRP45", "P25359", "RRP43", "YJL050W", "YOR001W" ] }, "reaction_10782565": { "compartment": "compartment_70101", "id": "reaction_10782565", "reactome": "R-SCE-6791223", "name": "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782539", "species_10782537" ], "products": [ "species_10782549", "species_10782541", "species_10762573", "species_10782555", "species_10782551", "species_10782539", "species_10782553", "species_10782557", "species_10782547", "species_10782545", "species_10782543" ], "modifiers": [ [ "species_10782545", "catalyst" ], [ "species_10782555", "catalyst" ], [ "species_10782563", "catalyst" ], [ "species_10782557", "catalyst" ] ], "additional_components": [ "YOR119C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "Q12196", "YOR119C", "P0CH08", "RPL40A", "P38333", "YBR247C", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "P34078", "YKL143W", "P0CX37", "RPS6A", "P38711", "RPS27B", "P38786", "YHR062C", "P0CX30", "RPS23B", "P40571", "YIR015W", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P50109", "YML017W", "P07280", "RPS19A", "P0CX39", "RPS8A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P0CX32", "RPS24B", "P40160", "YNL207W", "Q99216", "YOR145C", "P0CX35", "RPS4A", "P23248", "RPS1B", "P0CX47", "RPS11A", "P0CX56", "RPS18B", "P26786", "RPS7A", "Q01855", "RPS15", "P29295", "YPL204W", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "Q08444", "YOR056C", "P0CX40", "RPS8B", "P14127", "RPS17B", "Q07381", "YDL060W", "YNL207W", "YBR247C", "P0CX52", "RPS16B", "P35997", "RPS27A", "Q08745", "RPS10A", "P46784", "RPS10B", "P25443", "RPS2", "P06367", "RPS14A", "P0CX55", "RPS18A", "P0CX32", "RPS24B", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX35", "RPS4A", "P23248", "RPS1B", "P0CH08", "RPL40A", "P0CX47", "RPS11A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "P0CX37", "RPS6A", "P0CX56", "RPS18B", "P38711", "RPS27B", "P26786", "RPS7A", "P0CX30", "RPS23B", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P07281", "RPS19B", "P05759", "RPS31", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "YPL204W", "YDL060W", "YOR119C", "YOR119C", "YPL204W", "YOR145C", "YOR056C", "YKL143W", "YOR056C", "YPL204W", "YCR047C", "YPL204W" ] }, "reaction_10782116": { "compartment": "compartment_7660", "id": "reaction_10782116", "reactome": "R-SCE-6791219", "name": "32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782100" ], "products": [ "species_10782067" ], "modifiers": [ [ "species_10782063", "catalyst" ], [ "species_10782098", "catalyst" ], [ "species_10782114", "catalyst" ], [ "species_10782058", "catalyst" ] ], "additional_components": [ "Q12024", "YOR272W", "P38883", "YHR197W", "Q07845", "YLL035W", "P38803", "YHR085W", "P36146", "YKR063C", "Q02724", "YPL020C", "P53877", "YNL182C", "P53261", "YGR103W", "Q04660", "YMR049C", "P38883", "YHR197W", "Q07845", "YLL035W", "P38803", "YHR085W", "P36146", "YKR063C", "Q02724", "YPL020C", "P53877", "YNL182C", "YLL035W", "Q12024", "YOR272W", "P53261", "YGR103W", "Q04660", "YMR049C", "P36049", "YKL172W", "P40010", "YER006W", "P53261", "YGR103W", "YKR063C" ] }, "reaction_10767666": { "compartment": "compartment_70101", "id": "reaction_10767666", "reactome": "R-SCE-202164", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767662", "species_202277" ], "products": [ "species_10767664" ], "modifiers": [], "additional_components": [ "YOL100W", "species_202247", "species_179838", "species_202247", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10767681": { "compartment": "compartment_876", "id": "reaction_10767681", "reactome": "R-SCE-202222", "name": "Phosphorylation of PKC theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767671", "species_113592" ], "products": [ "species_29370", "species_10767678" ], "modifiers": [ [ "species_10767664", "catalyst" ] ], "additional_components": [ "species_112275", "P24583", "YBL105C", "species_112275", "P24583", "YBL105C", "species_202247", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10767319": { "compartment": "compartment_70101", "id": "reaction_10767319", "reactome": "R-SCE-199456", "name": "PTEN dephosphorylates PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_29356" ], "products": [ "species_29372", "species_179856" ], "modifiers": [ [ "species_10767316", "catalyst" ] ], "additional_components": [ "YNL128W" ] }, "reaction_10767687": { "compartment": "compartment_70101", "id": "reaction_10767687", "reactome": "R-SCE-202328", "name": "Translocation of PKC theta to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767566", "species_112275" ], "products": [ "species_10767685" ], "modifiers": [], "additional_components": [ "YBL105C", "species_112275", "P24583", "YBL105C" ] }, "reaction_10764508": { "compartment": "compartment_7660", "id": "reaction_10764508", "reactome": "R-SCE-109639", "name": "Formation of the closed pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763293", "species_10763806" ], "products": [ "species_10764070" ], "modifiers": [], "additional_components": [ "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "P32774", "YKL058W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10764504": { "compartment": "compartment_7660", "id": "reaction_10764504", "reactome": "R-SCE-109637", "name": "Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763800", "species_10763417", "species_10763422" ], "products": [ "species_10763802" ], "modifiers": [], "additional_components": [ "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "P32774", "YKL058W", "P32773", "YOR194C", "YPR086W", "Q04226", "YML015C", "Q12030", "YDR167W", "P23255", "YCR042C", "Q05021", "YMR227C", "P53040", "YGL112C", "P32774", "YKL058W", "P29055", "YPR086W", "Q03761", "YDR145W", "P13393", "SPT15", "Q05027", "YMR236W", "P38129", "YBR198C", "P50105", "YMR005W", "P46677", "YGR274C", "P11747", "YML098W", "P32773", "YOR194C" ] }, "reaction_10763808": { "compartment": "compartment_7660", "id": "reaction_10763808", "reactome": "R-SCE-75095", "name": "Binding of TFIIE to the growing preinitiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763503", "species_10763804" ], "products": [ "species_10763806" ], "modifiers": [], "additional_components": [ "P36100", "YKL028W", "P36145", "YKR062W", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "P32774", "YKL058W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P11747", "YML098W", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "P32774", "YKL058W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W" ] }, "reaction_10764502": { "compartment": "compartment_7660", "id": "reaction_10764502", "reactome": "R-SCE-109636", "name": "Recognition and Binding of Core Promoter Elements by TFIID", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109627", "species_10763491" ], "products": [ "species_10763800" ], "modifiers": [], "additional_components": [ "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15" ] }, "reaction_10764506": { "compartment": "compartment_7660", "id": "reaction_10764506", "reactome": "R-SCE-109638", "name": "Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762312", "species_10763802" ], "products": [ "species_10763804" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "Q04226", "YML015C", "Q12030", "YDR167W", "P23255", "YCR042C", "Q05021", "YMR227C", "P53040", "YGL112C", "P32774", "YKL058W", "P29055", "YPR086W", "Q03761", "YDR145W", "P13393", "SPT15", "Q05027", "YMR236W", "P38129", "YBR198C", "P50105", "YMR005W", "P46677", "YGR274C", "P11747", "YML098W", "P32773", "YOR194C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "P32774", "YKL058W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P11747", "YML098W" ] }, "reaction_10769195": { "compartment": "compartment_876", "id": "reaction_10769195", "reactome": "R-SCE-399998", "name": "Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10769192", "catalyst" ] ], "additional_components": [ "P32383", "YPL268W", "species_29438", "P10823", "YER020W" ] }, "reaction_10772682": { "compartment": "compartment_70101", "id": "reaction_10772682", "reactome": "R-SCE-1237160", "name": "MTA is cleaved and phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353106", "species_29372" ], "products": [ "species_83951", "species_1237165" ], "modifiers": [ [ "species_10772679", "catalyst" ] ], "additional_components": [ "Q07938", "YLR017W" ] }, "reaction_10772662": { "compartment": "compartment_70101", "id": "reaction_10772662", "reactome": "R-SCE-1237119", "name": "Acireductone is oxidized to MOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237155", "species_29368" ], "products": [ "species_1237122", "species_29460" ], "modifiers": [ [ "species_10772659", "catalyst" ] ], "additional_components": [ "species_111793", "Q03677", "YMR009W" ] }, "reaction_10772652": { "compartment": "compartment_70101", "id": "reaction_10772652", "reactome": "R-SCE-1237096", "name": "Methylthio-ribose-P = Methylthio-ribulose-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237165" ], "products": [ "species_1237107" ], "modifiers": [ [ "species_10772649", "catalyst" ] ], "additional_components": [ "YPR118W" ] }, "reaction_10772672": { "compartment": "compartment_70101", "id": "reaction_10772672", "reactome": "R-SCE-1237129", "name": "Acireductone is created", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237176", "species_29356" ], "products": [ "species_70106", "species_1237155", "species_29372" ], "modifiers": [ [ "species_10772669", "catalyst" ] ], "additional_components": [ "P32626", "YEL038W", "species_109496" ] }, "reaction_10787565": { "compartment": "compartment_70101", "id": "reaction_10787565", "reactome": "R-SCE-8951727", "name": "cAMP binds PKA tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764953", "species_30389" ], "products": [ "species_10764955" ], "modifiers": [], "additional_components": [ "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "species_30389" ] }, "reaction_10788654": { "compartment": "compartment_70101", "id": "reaction_10788654", "reactome": "R-SCE-9619355", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10788647" ], "products": [ "species_29370", "species_10788651" ], "modifiers": [ [ "species_10788647", "catalyst" ] ], "additional_components": [ "P06787", "YBR109C", "P43637", "YGL179C", "species_74016", "P06787", "YBR109C", "P43637", "YGL179C", "species_74016", "P06787", "YBR109C", "P43637", "YGL179C", "species_74016" ] }, "reaction_10788663": { "compartment": "compartment_70101", "id": "reaction_10788663", "reactome": "R-SCE-9619376", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767628", "species_10788659" ], "products": [ "species_10788661" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_74016", "YLR248W", "P06787", "YBR109C", "P38623", "YLR248W", "species_74016" ] }, "reaction_10764959": { "compartment": "compartment_70101", "id": "reaction_10764959", "reactome": "R-SCE-111925", "name": "cAMP induces dissociation of inactive PKA tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764955" ], "products": [ "species_10764957", "species_10764951" ], "modifiers": [], "additional_components": [ "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "species_30389", "P07278", "YIL033C", "species_30389", "P05986", "YKL166C", "P06245", "YPL203W", "P06244", "YJL164C" ] }, "reaction_10789248": { "compartment": "compartment_12045", "id": "reaction_10789248", "reactome": "R-SCE-9714361", "name": "RHOC activates endoplasmic reticulum effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789244", "species_10789214" ], "products": [ "species_10789246" ], "modifiers": [], "additional_components": [ "Q01590", "YLR026C", "Q12396", "YLR080W", "P43555", "YFL048C", "P36137", "YKR044W", "P40075", "YER120W", "P32462", "YNL280C", "Q6Q595", "YBL091C-A", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q01590", "YLR026C", "Q12396", "YLR080W", "Q00246", "YKR055W", "P06781", "YNL090W", "P43555", "YFL048C", "P36137", "YKR044W", "P06780", "YPR165W", "P40075", "YER120W", "species_29438", "P32462", "YNL280C", "Q6Q595", "YBL091C-A" ] }, "reaction_10788156": { "compartment": "compartment_876", "id": "reaction_10788156", "reactome": "R-SCE-9013437", "name": "RHOD GAPs stimulate RHOD GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136", "species_29356" ], "products": [ "species_29372", "species_10788124" ], "modifiers": [ [ "species_10788153", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "P39960", "YER155C", "Q06407", "YDR379W", "P38339", "YBR260C", "P32873", "YPL115C", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10789129": { "compartment": "compartment_17906", "id": "reaction_10789129", "reactome": "R-SCE-9693214", "name": "RHOD binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788063", "species_10789123" ], "products": [ "species_10789127" ], "modifiers": [], "additional_components": [ "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "P48562", "YNL298W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "Q03497", "YHL007C", "P06780", "YPR165W", "species_29438", "Q12469", "YOL113W" ] }, "reaction_10788047": { "compartment": "compartment_70101", "id": "reaction_10788047", "reactome": "R-SCE-9013108", "name": "GDIs block activation of RHOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787983", "species_10788033" ], "products": [ "species_10788045" ], "modifiers": [], "additional_components": [ "YDL135C", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29420", "Q12434", "YDL135C", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W" ] }, "reaction_10789250": { "compartment": "compartment_876", "id": "reaction_10789250", "reactome": "R-SCE-9714363", "name": "RHOC translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778611" ], "products": [ "species_10789214" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10788248": { "compartment": "compartment_876", "id": "reaction_10788248", "reactome": "R-SCE-9018768", "name": "RHOU auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10788245" ], "products": [ "species_10788230", "species_29420" ], "modifiers": [ [ "species_10788245", "catalyst" ] ], "additional_components": [ "species_29420", "P19073", "YLR229C", "species_29438", "P19073", "YLR229C", "species_29420", "P19073", "YLR229C" ] }, "reaction_10788109": { "compartment": "compartment_876", "id": "reaction_10788109", "reactome": "R-SCE-9013161", "name": "CDC42 GAPs stimulate CDC42 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10768894" ], "products": [ "species_10788091", "species_29372" ], "modifiers": [ [ "species_10788106", "catalyst" ] ], "additional_components": [ "species_29438", "P19073", "YLR229C", "species_29420", "P19073", "YLR229C", "P39960", "YER155C", "Q12128", "YOR134W", "Q06407", "YDR379W", "P38339", "YBR260C", "P32873", "YPL115C", "P17121", "YDR389W", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10789177": { "compartment": "compartment_70101", "id": "reaction_10789177", "reactome": "R-SCE-9696267", "name": "RND3 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10789173" ], "products": [ "species_10789175" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10788020": { "compartment": "compartment_70101", "id": "reaction_10788020", "reactome": "R-SCE-9013021", "name": "GDIs block activation of RHOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788014", "species_10788012" ], "products": [ "species_10788018" ], "modifiers": [], "additional_components": [ "YDL135C", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29420", "Q00245", "YIL118W", "Q12434", "YDL135C", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W" ] }, "reaction_10788031": { "compartment": "compartment_70101", "id": "reaction_10788031", "reactome": "R-SCE-9013024", "name": "RHOB binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788027", "species_10788022" ], "products": [ "species_10788029" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "Q08693", "YOR256C", "Q12280", "YPL242C", "P24583", "YBL105C", "P33328", "YOR327C", "P47161", "YJR126C", "Q04359", "YMR017W", "Q08919", "YPL176C", "P32525", "YJL201W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "P40357", "YGR009C", "Q08693", "YOR256C", "Q00246", "YKR055W", "P06781", "YNL090W", "P33328", "YOR327C", "P47161", "YJR126C", "Q04359", "YMR017W", "species_29438", "Q08919", "YPL176C", "P32525", "YJL201W", "Q00245", "YIL118W", "Q12280", "YPL242C", "P24583", "YBL105C", "P06780", "YPR165W" ] }, "reaction_10788295": { "compartment": "compartment_876", "id": "reaction_10788295", "reactome": "R-SCE-9018806", "name": "RAC3 GAPs stimulate RAC3 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788278", "species_29356" ], "products": [ "species_10788276", "species_29372" ], "modifiers": [ [ "species_10788292", "catalyst" ] ], "additional_components": [ "P53879", "YNL180C", "species_29438", "species_29420", "P53879", "YNL180C", "P39960", "YER155C", "Q06407", "YDR379W", "P38339", "YBR260C", "Q08227", "YOL065C", "P32873", "YPL115C", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10788305": { "compartment": "compartment_876", "id": "reaction_10788305", "reactome": "R-SCE-9018807", "name": "RAC3 GDIs block activation of RAC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788276", "species_10788297" ], "products": [ "species_10788303" ], "modifiers": [], "additional_components": [ "species_29420", "P53879", "YNL180C", "Q12434", "YDL135C", "species_29420", "P53879", "YNL180C", "Q12434", "YDL135C" ] }, "reaction_10789282": { "compartment": "compartment_876", "id": "reaction_10789282", "reactome": "R-SCE-9726862", "name": "Phosphorylated RHOU translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789276" ], "products": [ "species_10789280" ], "modifiers": [], "additional_components": [ "species_29420", "P19073", "YLR229C", "species_29420", "P19073", "YLR229C" ] }, "reaction_10788265": { "compartment": "compartment_876", "id": "reaction_10788265", "reactome": "R-SCE-9018794", "name": "RHOV binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788252", "species_10788261" ], "products": [ "species_10788263" ], "modifiers": [], "additional_components": [ "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "P39960", "YER155C", "Q03497", "YHL007C", "Q12280", "YPL242C", "Q06407", "YDR379W", "Q08924", "YPL183C", "P38339", "YBR260C", "P22137", "YGL206C", "P32873", "YPL115C", "Q12469", "YOL113W", "P17536", "YNL079C", "P19073", "YLR229C", "P39083", "YOR127W", "P48562", "YNL298W", "P39960", "YER155C", "P38339", "YBR260C", "species_29438", "P19073", "YLR229C", "Q03497", "YHL007C", "Q12280", "YPL242C", "Q06407", "YDR379W", "Q08924", "YPL183C", "P22137", "YGL206C", "P32873", "YPL115C", "Q12469", "YOL113W", "P17536", "YNL079C", "P39083", "YOR127W" ] }, "reaction_10788184": { "compartment": "compartment_876", "id": "reaction_10788184", "reactome": "R-SCE-9013438", "name": "RHOD binds effectors at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788168", "species_10788180" ], "products": [ "species_10788182" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "P40578", "YIR033W", "P35210", "YKL020C", "P32462", "YNL280C", "Q12091", "YPL170W", "P40578", "YIR033W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P35210", "YKL020C", "P06780", "YPR165W", "P32462", "YNL280C", "species_29438", "Q12091", "YPL170W" ] }, "reaction_10787825": { "compartment": "compartment_70101", "id": "reaction_10787825", "reactome": "R-SCE-8981637", "name": "RHOA GAPs stimulate RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10765231" ], "products": [ "species_10765229", "species_29372" ], "modifiers": [ [ "species_10787822", "catalyst" ] ], "additional_components": [ "P06780", "YPR165W", "species_29438", "species_29420", "P06780", "YPR165W", "P39960", "YER155C", "Q12128", "YOR134W", "Q06407", "YDR379W", "P38339", "YBR260C", "P32873", "YPL115C", "P17121", "YDR389W", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10788139": { "compartment": "compartment_876", "id": "reaction_10788139", "reactome": "R-SCE-9013435", "name": "RHOD auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10788124" ], "products": [ "species_10788136", "species_29420" ], "modifiers": [ [ "species_10788124", "catalyst" ] ], "additional_components": [ "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W" ] }, "reaction_10789125": { "compartment": "compartment_876", "id": "reaction_10789125", "reactome": "R-SCE-9693207", "name": "RHOD translocates to the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136" ], "products": [ "species_10789123" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10789143": { "compartment": "compartment_876", "id": "reaction_10789143", "reactome": "R-SCE-9693243", "name": "RHOD translocates to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136" ], "products": [ "species_10789141" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10788102": { "compartment": "compartment_876", "id": "reaction_10788102", "reactome": "R-SCE-9013159", "name": "CDC42 GEFs activate CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10788091" ], "products": [ "species_29420", "species_10768894" ], "modifiers": [ [ "species_10788099", "catalyst" ] ], "additional_components": [ "species_29420", "P19073", "YLR229C", "species_29438", "P19073", "YLR229C", "P04821", "YLR310C", "Q05670", "YMR232W", "P34216", "YBL047C", "P07866", "YAL024C", "P25300", "YCR038C", "P10823", "YER020W" ] }, "reaction_10789145": { "compartment": "compartment_876", "id": "reaction_10789145", "reactome": "R-SCE-9693282", "name": "RHOF GAPs stimulate RHOF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789100", "species_29356" ], "products": [ "species_10789098", "species_29372" ], "modifiers": [ [ "species_10788153", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "P39960", "YER155C", "Q06407", "YDR379W", "P38339", "YBR260C", "P32873", "YPL115C", "P39083", "YOR127W", "P32525", "YJL201W" ] }, "reaction_10788269": { "compartment": "compartment_876", "id": "reaction_10788269", "reactome": "R-SCE-9018798", "name": "RHOV binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10788267" ], "products": [ "species_10788252", "species_29420" ], "modifiers": [], "additional_components": [ "species_29420", "P19073", "YLR229C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10787993": { "compartment": "compartment_876", "id": "reaction_10787993", "reactome": "R-SCE-9013006", "name": "RHOA:GTP translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765231" ], "products": [ "species_10787991" ], "modifiers": [], "additional_components": [ "P06780", "YPR165W", "species_29438", "P06780", "YPR165W", "species_29438" ] }, "reaction_10787743": { "compartment": "compartment_70101", "id": "reaction_10787743", "reactome": "R-SCE-8980691", "name": "RHOA GEFs activate RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10765229" ], "products": [ "species_10765231", "species_29420" ], "modifiers": [ [ "species_10787740", "catalyst" ] ], "additional_components": [ "species_29420", "P06780", "YPR165W", "P06780", "YPR165W", "species_29438", "P04821", "YLR310C", "Q06409", "YLR422W", "P07866", "YAL024C", "P25300", "YCR038C" ] }, "reaction_10789092": { "compartment": "compartment_876", "id": "reaction_10789092", "reactome": "R-SCE-9690494", "name": "RHOB translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788022" ], "products": [ "species_10778663" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10788010": { "compartment": "compartment_876", "id": "reaction_10788010", "reactome": "R-SCE-9013009", "name": "RHOA binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788006", "species_10765231" ], "products": [ "species_10788008" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "Q08693", "YOR256C", "P33328", "YOR327C", "P22213", "YDR189W", "P47161", "YJR126C", "Q12229", "YDL091C", "Q04359", "YMR017W", "Q08919", "YPL176C", "P32525", "YJL201W", "Q12280", "YPL242C", "P24583", "YBL105C", "P40513", "YIL070C", "P36126", "YKR031C", "Q04228", "YML013W", "P06780", "YPR165W", "species_29438", "P40357", "YGR009C", "Q08693", "YOR256C", "P33328", "YOR327C", "P22213", "YDR189W", "P47161", "YJR126C", "Q12229", "YDL091C", "Q04359", "YMR017W", "species_29438", "Q08919", "YPL176C", "P32525", "YJL201W", "Q12280", "YPL242C", "P24583", "YBL105C", "P06780", "YPR165W", "P40513", "YIL070C", "P36126", "YKR031C", "Q04228", "YML013W" ] }, "reaction_10788053": { "compartment": "compartment_876", "id": "reaction_10788053", "reactome": "R-SCE-9013110", "name": "RHOC binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778611", "species_10788049" ], "products": [ "species_10788051" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q08693", "YOR256C", "Q12280", "YPL242C", "P24583", "YBL105C", "P33328", "YOR327C", "P06780", "YPR165W", "P40513", "YIL070C", "P47161", "YJR126C", "Q08919", "YPL176C", "P32525", "YJL201W", "Q00245", "YIL118W", "Q08693", "YOR256C", "Q00246", "YKR055W", "P06781", "YNL090W", "Q12280", "YPL242C", "P24583", "YBL105C", "P33328", "YOR327C", "P06780", "YPR165W", "P40513", "YIL070C", "P47161", "YJR126C", "species_29438", "Q08919", "YPL176C", "P32525", "YJL201W" ] }, "reaction_10788186": { "compartment": "compartment_876", "id": "reaction_10788186", "reactome": "R-SCE-9013452", "name": "RHOD:GTP translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136" ], "products": [ "species_10788168" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10789194": { "compartment": "compartment_70101", "id": "reaction_10789194", "reactome": "R-SCE-9696271", "name": "RND1 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769249", "species_10789190" ], "products": [ "species_10789192" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q08693", "YOR256C", "P19158", "YOL081W", "Q08924", "YPL183C", "P01120", "YNL098C", "Q04458", "YMR110C", "P15705", "YOR027W", "P18963", "YBR140C", "P47161", "YJR126C", "Q08919", "YPL176C", "Q08693", "YOR256C", "Q00246", "YKR055W", "P06781", "YNL090W", "P01120", "YNL098C", "P15705", "YOR027W", "P18963", "YBR140C", "P47161", "YJR126C", "species_29438", "Q08919", "YPL176C", "Q00245", "YIL118W", "P19158", "YOL081W", "Q08924", "YPL183C", "P06780", "YPR165W", "Q04458", "YMR110C" ] }, "reaction_10788055": { "compartment": "compartment_876", "id": "reaction_10788055", "reactome": "R-SCE-9013111", "name": "RHOC GAPs stimulate RHOC GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778611", "species_29356" ], "products": [ "species_10788033", "species_29372" ], "modifiers": [ [ "species_10787796", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "YJL201W" ] }, "reaction_10789111": { "compartment": "compartment_70101", "id": "reaction_10789111", "reactome": "R-SCE-9693198", "name": "RHOD binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788136", "species_10789107" ], "products": [ "species_10789109" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "P48562", "YNL298W", "Q03497", "YHL007C", "P13517", "YIL034C", "P33328", "YOR327C", "P15891", "YCR088W", "P32939", "YML001W", "Q12469", "YOL113W", "P32525", "YJL201W", "P48562", "YNL298W", "Q00245", "YIL118W", "Q03497", "YHL007C", "Q00246", "YKR055W", "P06781", "YNL090W", "P13517", "YIL034C", "P33328", "YOR327C", "P15891", "YCR088W", "P32939", "YML001W", "P06780", "YPR165W", "species_29438", "Q12469", "YOL113W", "P32525", "YJL201W" ] }, "reaction_10789196": { "compartment": "compartment_70101", "id": "reaction_10789196", "reactome": "R-SCE-9696274", "name": "RND1 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10769247" ], "products": [ "species_10769249" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10789103": { "compartment": "compartment_876", "id": "reaction_10789103", "reactome": "R-SCE-9693111", "name": "RHOF auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10789098" ], "products": [ "species_10789100", "species_29420" ], "modifiers": [ [ "species_10789098", "catalyst" ] ], "additional_components": [ "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W" ] }, "reaction_10787989": { "compartment": "compartment_70101", "id": "reaction_10787989", "reactome": "R-SCE-9012835", "name": "GDIs block activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787983", "species_10765229" ], "products": [ "species_10787987" ], "modifiers": [], "additional_components": [ "YDL135C", "species_29420", "P06780", "YPR165W", "species_29420", "Q12434", "YDL135C", "P06780", "YPR165W" ] }, "reaction_10789096": { "compartment": "compartment_876", "id": "reaction_10789096", "reactome": "R-SCE-9692800", "name": "CDC42 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768894" ], "products": [ "species_10789094" ], "modifiers": [], "additional_components": [ "species_29438", "P19073", "YLR229C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10788243": { "compartment": "compartment_876", "id": "reaction_10788243", "reactome": "R-SCE-9018766", "name": "RHOU binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788230", "species_10788239" ], "products": [ "species_10788241" ], "modifiers": [], "additional_components": [ "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "P53281", "YGR136W", "P39940", "YER125W", "Q03497", "YHL007C", "Q12280", "YPL242C", "P38753", "YHL002W", "Q08924", "YPL183C", "P34216", "YBL047C", "P39013", "YNL084C", "P22137", "YGL206C", "P32521", "YIR006C", "Q12469", "YOL113W", "P19073", "YLR229C", "P48562", "YNL298W", "P53281", "YGR136W", "P39940", "YER125W", "P38753", "YHL002W", "P34216", "YBL047C", "species_29438", "P19073", "YLR229C", "Q03497", "YHL007C", "Q12280", "YPL242C", "Q08924", "YPL183C", "P39013", "YNL084C", "P22137", "YGL206C", "P32521", "YIR006C", "Q12469", "YOL113W" ] }, "reaction_10788095": { "compartment": "compartment_876", "id": "reaction_10788095", "reactome": "R-SCE-9013158", "name": "CDC42 GDIs block activation of CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787983", "species_10788091" ], "products": [ "species_10788093" ], "modifiers": [], "additional_components": [ "YDL135C", "species_29420", "P19073", "YLR229C", "species_29420", "Q12434", "YDL135C", "P19073", "YLR229C" ] }, "reaction_10788025": { "compartment": "compartment_70101", "id": "reaction_10788025", "reactome": "R-SCE-9013022", "name": "RHOB GAPs stimulate RHOB GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10788022" ], "products": [ "species_10788012", "species_29372" ], "modifiers": [ [ "species_10787796", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "species_29420", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "YJL201W" ] }, "reaction_10789198": { "compartment": "compartment_70101", "id": "reaction_10789198", "reactome": "R-SCE-9696275", "name": "RND2 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10789161" ], "products": [ "species_10789163" ], "modifiers": [], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438" ] }, "reaction_10789256": { "compartment": "compartment_876", "id": "reaction_10789256", "reactome": "R-SCE-9714694", "name": "RAC3 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788278" ], "products": [ "species_10789254" ], "modifiers": [], "additional_components": [ "P53879", "YNL180C", "species_29438", "P53879", "YNL180C", "species_29438" ] }, "reaction_10764078": { "compartment": "compartment_7660", "id": "reaction_10764078", "reactome": "R-SCE-75866", "name": "Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764066" ], "products": [ "species_10764074" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q05027", "YMR236W", "species_6806881", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "P38129", "YBR198C", "Q02939", "YPL122C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32774", "YKL058W", "P32776", "YDR311W", "P13393", "SPT15", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10764086": { "compartment": "compartment_7660", "id": "reaction_10764086", "reactome": "R-SCE-75873", "name": "Addition of Nucleotides 5 through 9 on the growing Transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764080" ], "products": [ "species_10763503", "species_10763491", "species_113541", "species_10763417", "species_10764084" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P36100", "YKL028W", "P36145", "YKR062W", "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "P32774", "YKL058W", "P32773", "YOR194C", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764068": { "compartment": "compartment_7660", "id": "reaction_10764068", "reactome": "R-SCE-75861", "name": "NTP Binds Active Site of RNA Polymerase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764062" ], "products": [ "species_10764066" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q05027", "YMR236W", "species_6806881", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "P38129", "YBR198C", "Q02939", "YPL122C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "P23255", "YCR042C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32774", "YKL058W", "P32776", "YDR311W", "P13393", "SPT15", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10764035": { "compartment": "compartment_7660", "id": "reaction_10764035", "reactome": "R-SCE-75850", "name": "Addition of the third nucleotide on the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10763505" ], "products": [ "species_10764032", "species_113541" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764285": { "compartment": "compartment_7660", "id": "reaction_10764285", "reactome": "R-SCE-76576", "name": "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764084" ], "products": [ "species_10764283", "species_113541" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764082": { "compartment": "compartment_7660", "id": "reaction_10764082", "reactome": "R-SCE-75869", "name": "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764032" ], "products": [ "species_10764080", "species_113541", "species_10763422" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "YPR086W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10788639": { "compartment": "compartment_7660", "id": "reaction_10788639", "reactome": "R-SCE-9613497", "name": "Unwinding DNA for the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10763505" ], "products": [ "species_10763505", "species_113541" ], "modifiers": [ [ "species_10763293", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W" ] }, "reaction_10788637": { "compartment": "compartment_7660", "id": "reaction_10788637", "reactome": "R-SCE-9613494", "name": "Unwinding of DNA for the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10764032" ], "products": [ "species_10764032", "species_164121", "species_113541" ], "modifiers": [ [ "species_10763293", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W" ] }, "reaction_10764076": { "compartment": "compartment_7660", "id": "reaction_10764076", "reactome": "R-SCE-75864", "name": "Newly Formed Phosphodiester Bond Stabilized and PPi Released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764074" ], "products": [ "species_10763505", "species_113541" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10764162": { "compartment": "compartment_7660", "id": "reaction_10764162", "reactome": "R-SCE-75949", "name": "RNA Polymerase II Promoter Opening: First Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10764070" ], "products": [ "species_113582", "species_113550", "species_10764062" ], "modifiers": [ [ "species_10763293", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W" ] }, "reaction_10764829": { "compartment": "compartment_7660", "id": "reaction_10764829", "reactome": "R-SCE-111264", "name": "Addition of nucleotides between position +11 and +30", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10764283" ], "products": [ "species_10764338", "species_113541" ], "modifiers": [ [ "species_10762312", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10780889": { "compartment": "compartment_70101", "id": "reaction_10780889", "reactome": "R-SCE-5690152", "name": "USP5 cleaves polyubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10780884", "species_29356" ], "products": [ "species_10760634", "species_10780886" ], "modifiers": [ [ "species_10780884", "catalyst" ] ], "additional_components": [ "P38237", "YBR058C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38237", "YBR058C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38237", "YBR058C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10781695": { "compartment": "compartment_7660", "id": "reaction_10781695", "reactome": "R-SCE-5697009", "name": "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781688", "species_113518" ], "products": [ "species_10780391", "species_10781692" ], "modifiers": [ [ "species_10781688", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "Q01939", "YGL048C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03940", "YDR190C", "P38187", "YBL067C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P13365", "YAL040C", "P20438", "YPL256C", "Q01939", "YGL048C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03940", "YDR190C", "P38187", "YBL067C", "P13365", "YAL040C", "P20438", "YPL256C", "Q01939", "YGL048C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03940", "YDR190C", "P38187", "YBL067C" ] }, "reaction_10780495": { "compartment": "compartment_7660", "id": "reaction_10780495", "reactome": "R-SCE-5690080", "name": "USP3,SAGA deubiquitinate Histone H2A,H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10780488", "species_113518" ], "products": [ "species_10780492", "species_10760537" ], "modifiers": [ [ "species_10780488", "catalyst" ] ], "additional_components": [ "Q05027", "YMR236W", "P50102", "YMR223W", "P02294", "YBL002W", "Q12030", "YDR167W", "P28003", "YAL034C", "P32494", "YDR176W", "Q99326", "YOR338W", "Q02336", "YDR448W", "Q03330", "YGR252W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "Q05027", "YMR236W", "P50102", "YMR223W", "P02294", "YBL002W", "Q12030", "YDR167W", "P28003", "YAL034C", "P32494", "YDR176W", "Q99326", "YOR338W", "Q02336", "YDR448W", "Q03330", "YGR252W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05027", "YMR236W", "P50102", "YMR223W", "P02294", "YBL002W", "Q12030", "YDR167W", "P28003", "YAL034C", "P32494", "YDR176W", "Q99326", "YOR338W", "Q02336", "YDR448W", "Q03330", "YGR252W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W" ] }, "reaction_10771848": { "compartment": "compartment_70101", "id": "reaction_10771848", "reactome": "R-SCE-936390", "name": "CYLD mediated deubiquitination of DDX58 (RIG-I)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771819" ], "products": [ "species_10760634", "species_10771837" ], "modifiers": [ [ "species_10771845", "catalyst" ] ], "additional_components": [ "P40434", "YML133C", "P40889", "YML133C", "Q7M4S9", "YML133C", "Q03099", "YML133C", "P53819", "YNL339C", "Q99208", "YML133C", "Q07888", "YML133C", "P38721", "YML133C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40434", "YML133C", "P40889", "YML133C", "Q7M4S9", "YML133C", "Q03099", "YML133C", "P53819", "YNL339C", "Q99208", "YML133C", "Q07888", "YML133C", "P38721", "YML133C", "P33442", "RPS1A", "P23248", "RPS1B" ] }, "reaction_10779645": { "compartment": "compartment_70101", "id": "reaction_10779645", "reactome": "R-SCE-5689539", "name": "ADRM1:26S proteaseome binds USP14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779636", "species_10779641" ], "products": [ "species_10779643" ], "modifiers": [], "additional_components": [ "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W", "YFR010W", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P43593", "YFR010W", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10781707": { "compartment": "compartment_70101", "id": "reaction_10781707", "reactome": "R-SCE-6781779", "name": "USP13 deubiquitinates BECN1,USP10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781702", "species_29356" ], "products": [ "species_10781704", "species_10766135" ], "modifiers": [ [ "species_10781702", "catalyst" ] ], "additional_components": [ "P38237", "YBR058C", "Q02948", "YPL120W", "P38237", "YBR058C", "Q02948", "YPL120W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38237", "YBR058C", "Q02948", "YPL120W" ] }, "reaction_10780394": { "compartment": "compartment_7660", "id": "reaction_10780394", "reactome": "R-SCE-5689950", "name": "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10779716" ], "products": [ "species_10780391", "species_10779722" ], "modifiers": [ [ "species_10779716", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "P50101", "YMR304W", "Q08747", "YOR295W", "P53916", "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P50101", "YMR304W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P53916", "YNL128W", "Q05024", "YMR233W", "P50101", "YMR304W", "Q08747", "YOR295W", "P53916", "YNL128W" ] }, "reaction_10761428": { "compartment": "compartment_70101", "id": "reaction_10761428", "reactome": "R-SCE-70523", "name": "PXLP-K314-GPT transaminates L-Ala to form PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29432" ], "products": [ "species_29404", "species_29398" ], "modifiers": [ [ "species_10761425", "catalyst" ] ], "additional_components": [ "P52893", "YLR089C" ] }, "reaction_10771076": { "compartment": "compartment_5460", "id": "reaction_10771076", "reactome": "R-SCE-507749", "name": "PXLP-K341-GPT2 transaminates PYR to form L-Ala", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113557" ], "products": [ "species_113594", "species_379697" ], "modifiers": [ [ "species_10771073", "catalyst" ] ], "additional_components": [ "P52893", "YLR089C", "P52892", "YDR111C" ] }, "reaction_10787978": { "compartment": "compartment_5460", "id": "reaction_10787978", "reactome": "R-SCE-9012721", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012724", "species_9012592" ], "products": [ "species_1614595", "species_113557" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C" ] }, "reaction_10788188": { "compartment": "compartment_5460", "id": "reaction_10788188", "reactome": "R-SCE-9013471", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013199", "species_9012592" ], "products": [ "species_113557", "species_9013191" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C" ] }, "reaction_10788112": { "compartment": "compartment_5460", "id": "reaction_10788112", "reactome": "R-SCE-9013198", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_9013199" ], "products": [ "species_9013207", "species_9013191" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C" ] }, "reaction_10788190": { "compartment": "compartment_5460", "id": "reaction_10788190", "reactome": "R-SCE-9013533", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013543", "species_9013199" ], "products": [ "species_113557", "species_9013191" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C" ] }, "reaction_10773393": { "compartment": "compartment_70101", "id": "reaction_10773393", "reactome": "R-SCE-1614567", "name": "Excess homocysteine yields homolanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369" ], "products": [ "species_1614532", "species_1614594" ], "modifiers": [ [ "species_10773390", "catalyst" ], [ "species_174369", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10773404": { "compartment": "compartment_70101", "id": "reaction_10773404", "reactome": "R-SCE-1614631", "name": "Homocysteine is degraded to oxobutanoate and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369", "species_29356" ], "products": [ "species_1614532", "species_29382", "species_936714" ], "modifiers": [ [ "species_10773390", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10773399": { "compartment": "compartment_70101", "id": "reaction_10773399", "reactome": "R-SCE-1614591", "name": "Excess cysteine yields lanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707" ], "products": [ "species_1614532", "species_1614582" ], "modifiers": [ [ "species_10773390", "catalyst" ], [ "species_111707", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10773401": { "compartment": "compartment_70101", "id": "reaction_10773401", "reactome": "R-SCE-1614614", "name": "Cysteine is degraded to serine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_29356" ], "products": [ "species_1614532", "species_200736" ], "modifiers": [ [ "species_10773390", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10788493": { "compartment": "compartment_5460", "id": "reaction_10788493", "reactome": "R-SCE-9034756", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787975", "species_9012592" ], "products": [ "species_113557", "species_10788491" ], "modifiers": [ [ "species_10787975", "catalyst" ] ], "additional_components": [ "YOR251C", "YOR251C", "YOR251C" ] }, "reaction_10773382": { "compartment": "compartment_70616", "id": "reaction_10773382", "reactome": "R-SCE-1614546", "name": "Sulfate is exported to the cytosol in exchange for dicarboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614584", "species_198498" ], "products": [ "species_174375", "species_113544" ], "modifiers": [ [ "species_10768552", "catalyst" ] ], "additional_components": [ "YLR348C" ] }, "reaction_10778010": { "compartment": "compartment_70101", "id": "reaction_10778010", "reactome": "R-SCE-5623508", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10778008" ], "products": [ "species_10778006", "species_29420" ], "modifiers": [ [ "species_10768383", "catalyst" ] ], "additional_components": [ "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "P11076", "YDL192W", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C" ] }, "reaction_10773127": { "compartment": "compartment_12045", "id": "reaction_10773127", "reactome": "R-SCE-1482825", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[11]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10773124", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10773178": { "compartment": "compartment_12045", "id": "reaction_10773178", "reactome": "R-SCE-1482932", "name": "PI is hydrolyzed to 2-acyl LPI by PLA2[13]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498737", "species_1524021" ], "modifiers": [ [ "species_10773175", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10773030": { "compartment": "compartment_12045", "id": "reaction_10773030", "reactome": "R-SCE-1482626", "name": "2-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498737", "species_1500578" ], "products": [ "species_76194", "species_426639" ], "modifiers": [ [ "species_10772972", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10772975": { "compartment": "compartment_12045", "id": "reaction_10772975", "reactome": "R-SCE-1482598", "name": "1-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498733", "species_1500578" ], "products": [ "species_76194", "species_426639" ], "modifiers": [ [ "species_10772972", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10773155": { "compartment": "compartment_12045", "id": "reaction_10773155", "reactome": "R-SCE-1482868", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[12]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10764802": { "compartment": "compartment_7660", "id": "reaction_10764802", "reactome": "R-SCE-110316", "name": "POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764798", "species_10764794" ], "products": [ "species_10764800" ], "modifiers": [], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "YDR419W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10764811": { "compartment": "compartment_7660", "id": "reaction_10764811", "reactome": "R-SCE-110317", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764800", "species_29604" ], "products": [ "species_113541", "species_10764808" ], "modifiers": [ [ "species_10764800", "catalyst" ] ], "additional_components": [ "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10778443": { "compartment": "compartment_7660", "id": "reaction_10778443", "reactome": "R-SCE-5654985", "name": "SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778439", "species_10778423" ], "products": [ "species_10778441" ], "modifiers": [], "additional_components": [ "P33755", "YBR170C", "P53044", "YGR048W", "P25694", "YDL126C", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P33755", "YBR170C", "P38630", "YOR217W", "P40339", "YOL094C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P53044", "YGR048W", "P25694", "YDL126C" ] }, "reaction_10778448": { "compartment": "compartment_7660", "id": "reaction_10778448", "reactome": "R-SCE-5654989", "name": "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10778441" ], "products": [ "species_113582", "species_10778445", "species_10764794" ], "modifiers": [ [ "species_10778441", "catalyst" ] ], "additional_components": [ "Q04049", "YDR419W", "P33755", "YBR170C", "P38630", "YOR217W", "P40339", "YOL094C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P53044", "YGR048W", "P25694", "YDL126C", "P33755", "YBR170C", "P38630", "YOR217W", "P40339", "YOL094C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P53044", "YGR048W", "P25694", "YDL126C", "YDR419W", "Q04049", "YDR419W", "P33755", "YBR170C", "P38630", "YOR217W", "P40339", "YOL094C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P53044", "YGR048W", "P25694", "YDL126C" ] }, "reaction_10764818": { "compartment": "compartment_7660", "id": "reaction_10764818", "reactome": "R-SCE-110319", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10764808" ], "products": [ "species_113541", "species_10764815" ], "modifiers": [ [ "species_10764808", "catalyst" ] ], "additional_components": [ "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "Q04049", "YDR419W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10785235": { "compartment": "compartment_12045", "id": "reaction_10785235", "reactome": "R-SCE-6814254", "name": "PNPLA6 hydrolyzes LysoPtdCho", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6814253", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10785232", "catalyst" ] ], "additional_components": [ "YML059C" ] }, "reaction_10785323": { "compartment": "compartment_876", "id": "reaction_10785323", "reactome": "R-SCE-6814797", "name": "ENPP6 hydrolyzes lysophosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2239407" ], "products": [ "species_6814794", "species_6814795" ], "modifiers": [ [ "species_10785320", "catalyst" ] ], "additional_components": [ "P39997", "YEL016C", "P25353", "YCR026C" ] }, "reaction_10773783": { "compartment": "compartment_70101", "id": "reaction_10773783", "reactome": "R-SCE-1855179", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629770" ], "modifiers": [ [ "species_10773780", "catalyst" ] ], "additional_components": [ "YDR315C" ] }, "reaction_10773735": { "compartment": "compartment_70101", "id": "reaction_10773735", "reactome": "R-SCE-1855165", "name": "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_1629765", "species_29372" ], "modifiers": [ [ "species_10773732", "catalyst" ] ], "additional_components": [ "CHEBI:62924", "species_2023931", "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773751": { "compartment": "compartment_7660", "id": "reaction_10773751", "reactome": "R-SCE-1855176", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023929" ], "modifiers": [ [ "species_10773748", "catalyst" ] ], "additional_components": [ "YDR315C" ] }, "reaction_10773839": { "compartment": "compartment_70101", "id": "reaction_10773839", "reactome": "R-SCE-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_994123", "species_29372" ], "modifiers": [ [ "species_10773740", "catalyst" ] ], "additional_components": [ "P50942", "YNL106C", "Q08227", "YOL065C" ] }, "reaction_10773738": { "compartment": "compartment_70101", "id": "reaction_10773738", "reactome": "R-SCE-1855166", "name": "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023943", "species_29356" ], "products": [ "species_29372", "species_994141" ], "modifiers": [ [ "species_10773726", "catalyst" ] ], "additional_components": [ "species_1629736", "species_2023922", "CHEBI:62927", "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773870": { "compartment": "compartment_70101", "id": "reaction_10773870", "reactome": "R-SCE-1855223", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629755" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773743": { "compartment": "compartment_70101", "id": "reaction_10773743", "reactome": "R-SCE-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114520", "species_29356" ], "products": [ "species_1629739", "species_29372" ], "modifiers": [ [ "species_10773740", "catalyst" ] ], "additional_components": [ "P50942", "YNL106C", "Q08227", "YOL065C" ] }, "reaction_10773702": { "compartment": "compartment_7660", "id": "reaction_10773702", "reactome": "R-SCE-1855157", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023932" ], "products": [ "species_113582", "species_2023931" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773778": { "compartment": "compartment_70101", "id": "reaction_10773778", "reactome": "R-SCE-1855178", "name": "Glc6P is isomerised to I3P by ISYNA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629756" ], "products": [ "species_1629731" ], "modifiers": [ [ "species_10773775", "catalyst" ] ], "additional_components": [ "species_113526", "P11986", "YJL153C" ] }, "reaction_10773810": { "compartment": "compartment_70101", "id": "reaction_10773810", "reactome": "R-SCE-1855205", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_114520", "species_29372" ], "modifiers": [ [ "species_10773807", "catalyst" ] ], "additional_components": [ "P53916", "YNL128W", "species_109496" ] }, "reaction_10773826": { "compartment": "compartment_876", "id": "reaction_10773826", "reactome": "R-SCE-1855213", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_994123", "species_29372" ], "modifiers": [ [ "species_10773821", "catalyst" ] ], "additional_components": [ "YOL065C" ] }, "reaction_10773715": { "compartment": "compartment_70101", "id": "reaction_10773715", "reactome": "R-SCE-1855158", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629759" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773968": { "compartment": "compartment_70101", "id": "reaction_10773968", "reactome": "R-SCE-2023971", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023974", "species_29356" ], "products": [ "species_1629770", "species_29372" ], "modifiers": [ [ "species_10773732", "catalyst" ] ], "additional_components": [ "CHEBI:62922", "species_2023932", "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773816": { "compartment": "compartment_70101", "id": "reaction_10773816", "reactome": "R-SCE-1855210", "name": "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629731" ], "products": [ "species_426910", "species_29372" ], "modifiers": [ [ "species_10773680", "catalyst" ] ], "additional_components": [ "P38710", "YHR046C", "Q05533", "YDR287W", "species_109496" ] }, "reaction_10773864": { "compartment": "compartment_876", "id": "reaction_10773864", "reactome": "R-SCE-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10773861", "catalyst" ] ], "additional_components": [ "species_74016", "P32383", "YPL268W" ] }, "reaction_10773813": { "compartment": "compartment_7660", "id": "reaction_10773813", "reactome": "R-SCE-1855207", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023929" ], "products": [ "species_113582", "species_2023940" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773867": { "compartment": "compartment_876", "id": "reaction_10773867", "reactome": "R-SCE-1855222", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114520", "species_29356" ], "products": [ "species_1629739", "species_29372" ], "modifiers": [ [ "species_10773821", "catalyst" ] ], "additional_components": [ "YOL065C" ] }, "reaction_10773786": { "compartment": "compartment_7660", "id": "reaction_10773786", "reactome": "R-SCE-1855181", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023922" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773876": { "compartment": "compartment_70101", "id": "reaction_10773876", "reactome": "R-SCE-1855227", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629770", "species_113592" ], "products": [ "species_29370", "species_1629765" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773768": { "compartment": "compartment_70101", "id": "reaction_10773768", "reactome": "R-SCE-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10773765", "catalyst" ] ], "additional_components": [ "P32383", "YPL268W", "species_74016" ] }, "reaction_10773799": { "compartment": "compartment_70101", "id": "reaction_10773799", "reactome": "R-SCE-1855193", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629736" ], "products": [ "species_29370", "species_1629738" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773836": { "compartment": "compartment_70101", "id": "reaction_10773836", "reactome": "R-SCE-1855216", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629770", "species_113592" ], "products": [ "species_29370", "species_1629740" ], "modifiers": [ [ "species_10773791", "catalyst" ] ], "additional_components": [ "YLR410W" ] }, "reaction_10773873": { "compartment": "compartment_7660", "id": "reaction_10773873", "reactome": "R-SCE-1855224", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023940", "species_29358" ], "products": [ "species_113582", "species_2023941" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773805": { "compartment": "compartment_70101", "id": "reaction_10773805", "reactome": "R-SCE-1855198", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_29356" ], "products": [ "species_1629770", "species_29372" ], "modifiers": [ [ "species_10773732", "catalyst" ] ], "additional_components": [ "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773819": { "compartment": "compartment_70101", "id": "reaction_10773819", "reactome": "R-SCE-1855211", "name": "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629753", "species_29356" ], "products": [ "species_426910", "species_29372" ], "modifiers": [ [ "species_10773680", "catalyst" ] ], "additional_components": [ "P38710", "YHR046C", "Q05533", "YDR287W", "species_109496" ] }, "reaction_10773796": { "compartment": "compartment_70101", "id": "reaction_10773796", "reactome": "R-SCE-1855182", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629732" ], "modifiers": [ [ "species_10773791", "catalyst" ] ], "additional_components": [ "YLR410W" ] }, "reaction_10773970": { "compartment": "compartment_70101", "id": "reaction_10773970", "reactome": "R-SCE-2023973", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_2023974", "species_29372" ], "modifiers": [ [ "species_10773732", "catalyst" ] ], "additional_components": [ "CHEBI:62924", "species_2023931", "CHEBI:62922", "species_2023932", "species_113527", "species_109496", "Q99321", "YOR163W" ] }, "reaction_10773879": { "compartment": "compartment_7660", "id": "reaction_10773879", "reactome": "R-SCE-1855230", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023922", "species_29358" ], "products": [ "species_113582", "species_2023948" ], "modifiers": [ [ "species_10773699", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773802": { "compartment": "compartment_70101", "id": "reaction_10773802", "reactome": "R-SCE-1855194", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629740" ], "products": [ "species_29370", "species_1629732" ], "modifiers": [ [ "species_10773712", "catalyst" ] ], "additional_components": [ "P07250", "YDR173C", "Q12494", "YDR017C" ] }, "reaction_10773833": { "compartment": "compartment_12045", "id": "reaction_10773833", "reactome": "R-SCE-1855214", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023856", "species_29356" ], "products": [ "species_114520", "species_1500596" ], "modifiers": [ [ "species_10773830", "catalyst" ] ], "additional_components": [ "species_74016", "P32383", "YPL268W" ] }, "reaction_10773683": { "compartment": "compartment_70101", "id": "reaction_10773683", "reactome": "R-SCE-1855154", "name": "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_870330", "species_29356" ], "products": [ "species_426910", "species_29372" ], "modifiers": [ [ "species_10773680", "catalyst" ] ], "additional_components": [ "P38710", "YHR046C", "Q05533", "YDR287W", "species_109496" ] }, "reaction_10778372": { "compartment": "compartment_7660", "id": "reaction_10778372", "reactome": "R-SCE-5653780", "name": "USP43 binds ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778364", "species_10778368" ], "products": [ "species_10778370" ], "modifiers": [], "additional_components": [ "P39538", "YJL197W", "P32571", "YDR069C", "P39944", "YER144C", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P39538", "YJL197W", "P38251", "YBR087W", "P32571", "YDR069C", "P15873", "YBR088C", "P38629", "YNL290W", "P39944", "YER144C" ] }, "reaction_10778378": { "compartment": "compartment_7660", "id": "reaction_10778378", "reactome": "R-SCE-5653838", "name": "POLD,POLE binds deISGylated PCNA after TLS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778374", "species_10764822" ], "products": [ "species_10778376" ], "modifiers": [], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P40366", "YJL065C", "P27344", "YBR278W", "P26754", "YNL312W", "P40339", "YOL094C", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10765202": { "compartment": "compartment_7660", "id": "reaction_10765202", "reactome": "R-SCE-113504", "name": "Detection of damage during initiation of DNA synthesis in S-phase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760830" ], "products": [ "species_10760246", "species_113656" ], "modifiers": [], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W" ] }, "reaction_10767970": { "compartment": "compartment_12045", "id": "reaction_10767970", "reactome": "R-SCE-203979", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767870", "species_10767966" ], "products": [ "species_10767968" ], "modifiers": [], "additional_components": [ "P20606", "YPL218W", "species_29438", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "species_29438" ] }, "reaction_10772440": { "compartment": "compartment_17957", "id": "reaction_10772440", "reactome": "R-SCE-983158", "name": "Trimming of peptides in ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983034" ], "products": [ "species_983033", "species_8943716" ], "modifiers": [ [ "species_10772437", "catalyst" ] ], "additional_components": [ "P40462", "YIL137C", "P32454", "YKL157W", "P37898", "YHR047C" ] }, "reaction_10761054": { "compartment": "compartment_7660", "id": "reaction_10761054", "reactome": "R-SCE-69199", "name": "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10761046" ], "products": [ "species_113550", "species_10761041" ], "modifiers": [ [ "species_10761051", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "YMR036C" ] }, "reaction_10766479": { "compartment": "compartment_7660", "id": "reaction_10766479", "reactome": "R-SCE-188350", "name": "CAK-mediated phosphorylation of Cyclin E:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10761041" ], "products": [ "species_113582", "species_10760879" ], "modifiers": [ [ "species_10763257", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03290", "YDR460W", "P37366", "YPR025C", "P06242", "YDL108W" ] }, "reaction_10760390": { "compartment": "compartment_7660", "id": "reaction_10760390", "reactome": "R-SCE-68918", "name": "CDK and DDK associate with the Mcm10:pre-replicative complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760326", "species_10760314", "species_10760375" ], "products": [ "species_10760377" ], "modifiers": [], "additional_components": [ "P06243", "YDL017W", "P32325", "YDR052C", "P00546", "YBR160W", "P24279", "MCM3", "P29469", "MCM2", "P32833", "ORC2", "P38132", "MCM7", "P54791", "ORC4", "P54784", "phospho-ORC1", "P30665", "MCM4", "P32354", "YIL150C", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P54790", "ORC3", "P29496", "MCM5", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "P54791", "ORC4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10760383": { "compartment": "compartment_7660", "id": "reaction_10760383", "reactome": "R-SCE-68914", "name": "DNA polymerase alpha:primase binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760246", "species_10760277" ], "products": [ "species_10760279" ], "modifiers": [ [ "species_10760381", "catalyst" ] ], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P20457", "YKL045W", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P22336", "YAR007C", "P54791", "ORC4", "P26754", "YNL312W", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10761037": { "compartment": "compartment_70101", "id": "reaction_10761037", "reactome": "R-SCE-69191", "name": "Formation of Cyclin E:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760999", "species_10761033" ], "products": [ "species_10761035" ], "modifiers": [], "additional_components": [ "YBR160W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760840": { "compartment": "compartment_7660", "id": "reaction_10760840", "reactome": "R-SCE-68960", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760275", "species_68419" ], "products": [ "species_10760277" ], "modifiers": [ [ "species_10760381", "catalyst" ] ], "additional_components": [ "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P22336", "YAR007C", "P54791", "ORC4", "P26754", "YNL312W", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10760838": { "compartment": "compartment_7660", "id": "reaction_10760838", "reactome": "R-SCE-68954", "name": "Mcm2-7 is phosphorylated by DDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10760363" ], "products": [ "species_113582", "species_10760835" ], "modifiers": [ [ "species_10760326", "catalyst" ] ], "additional_components": [ "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "species_29372", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29496", "MCM5", "P06243", "YDL017W", "P32325", "YDR052C" ] }, "reaction_10765436": { "compartment": "compartment_13231", "id": "reaction_10765436", "reactome": "R-SCE-157906", "name": "Translocation of Cyclin E:Cdk2 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761035" ], "products": [ "species_10761041" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760400": { "compartment": "compartment_7660", "id": "reaction_10760400", "reactome": "R-SCE-68919", "name": "Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760396", "species_10760331" ], "products": [ "species_10760398" ], "modifiers": [], "additional_components": [ "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P32833", "ORC2", "P54791", "ORC4", "P30665", "MCM4", "P54784", "phospho-ORC1", "P09119", "CDC6", "P53091", "MCM6", "P50874", "ORC5", "P29496", "MCM5", "P54790", "ORC3", "YIL150C", "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P32833", "ORC2", "P54791", "ORC4", "P30665", "MCM4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P09119", "CDC6", "P53091", "MCM6", "P50874", "ORC5", "P29496", "MCM5", "P54790", "ORC3" ] }, "reaction_10760388": { "compartment": "compartment_7660", "id": "reaction_10760388", "reactome": "R-SCE-68917", "name": "Cdc45 associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760377", "species_10760305" ], "products": [ "species_10760379" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "P54791", "ORC4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3", "YLR103C", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P54791", "ORC4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10760386": { "compartment": "compartment_7660", "id": "reaction_10760386", "reactome": "R-SCE-68916", "name": "DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760379", "species_10760300" ], "products": [ "species_10760381" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P54791", "ORC4", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3", "P22336", "YAR007C", "P26754", "YNL312W", "P32833", "ORC2", "P38132", "MCM7", "P30665", "MCM4", "P00546", "YBR160W", "P09119", "CDC6", "P50874", "ORC5", "P53091", "MCM6", "P32325", "YDR052C", "P29496", "MCM5", "P24279", "MCM3", "P29469", "MCM2", "P06243", "YDL017W", "Q08032", "YLR103C", "P22336", "YAR007C", "P54791", "ORC4", "P26754", "YNL312W", "P54784", "phospho-ORC1", "P32354", "YIL150C", "P54790", "ORC3" ] }, "reaction_10766866": { "compartment": "compartment_13231", "id": "reaction_10766866", "reactome": "R-SCE-193666", "name": "Active JNK moves to the nucleus and phosphorylates different transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765974" ], "products": [ "species_10765931" ], "modifiers": [], "additional_components": [ "YPR054W", "YPR054W" ] }, "reaction_10775479": { "compartment": "compartment_7660", "id": "reaction_10775479", "reactome": "R-SCE-3318486", "name": "KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_113560" ], "products": [ "species_2485002", "species_10775464" ], "modifiers": [ [ "species_10775476", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q12311", "YPR031W", "Q08465", "YOR064C", "Q08649", "YOR244W", "P50947", "YNL097C", "P38806", "YHR090C", "P47128", "YJR082C" ] }, "reaction_10775918": { "compartment": "compartment_7660", "id": "reaction_10775918", "reactome": "R-SCE-3662318", "name": "Type B histone acetlytransferase complex acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763701", "species_113560" ], "products": [ "species_2485002", "species_10775881" ], "modifiers": [ [ "species_10775915", "catalyst" ] ], "additional_components": [ "YBR009C", "YBR009C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P39984", "YEL056W", "Q12363", "YOR230W", "P13712", "YBR195C", "Q12341", "YPL001W" ] }, "reaction_10775460": { "compartment": "compartment_7660", "id": "reaction_10775460", "reactome": "R-SCE-3318415", "name": "ATF2 acetylates histone H2B, H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775434", "species_113560" ], "products": [ "species_2485002", "species_10775457" ], "modifiers": [ [ "species_10765915", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P02293", "YDR224C", "P02294", "YBL002W", "P02309", "YBR009C", "P02293", "YDR224C", "P39970", "YER045C", "P40535", "YIL036W", "Q02100", "YNL167C" ] }, "reaction_10775428": { "compartment": "compartment_7660", "id": "reaction_10775428", "reactome": "R-SCE-3318413", "name": "KAT7-containing ING4/5 complexes acetylate Me3K-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774208", "species_113560" ], "products": [ "species_2485002", "species_10775382" ], "modifiers": [ [ "species_10775425", "catalyst" ] ], "additional_components": [ "YKL049C", "YKL049C", "Q08465", "YOR064C", "Q08649", "YOR244W", "P50947", "YNL097C", "P38806", "YHR090C", "P47128", "YJR082C" ] }, "reaction_10764336": { "compartment": "compartment_7660", "id": "reaction_10764336", "reactome": "R-SCE-77069", "name": "RNA Polymerase II CTD (phosphorylated) binds to CE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764328", "species_10764334" ], "products": [ "species_10764330" ], "modifiers": [], "additional_components": [ "YGL130W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q01159", "YGL130W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10764381": { "compartment": "compartment_7660", "id": "reaction_10764381", "reactome": "R-SCE-77085", "name": "Dissociation of transcript with 5'-GMP from GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764374" ], "products": [ "species_10764379" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764377": { "compartment": "compartment_7660", "id": "reaction_10764377", "reactome": "R-SCE-77083", "name": "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764369" ], "products": [ "species_10764374" ], "modifiers": [ [ "species_10764369", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "species_113578", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "species_113578", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764360": { "compartment": "compartment_7660", "id": "reaction_10764360", "reactome": "R-SCE-77077", "name": "Capping complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_72084", "species_10764354", "species_29428" ], "products": [ "species_10764358" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764365": { "compartment": "compartment_7660", "id": "reaction_10764365", "reactome": "R-SCE-77078", "name": "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764358" ], "products": [ "species_113550", "species_10764362" ], "modifiers": [ [ "species_10764358", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764332": { "compartment": "compartment_7660", "id": "reaction_10764332", "reactome": "R-SCE-77068", "name": "Activation of GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764330" ], "products": [ "species_10764330" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q01159", "YGL130W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q01159", "YGL130W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10764386": { "compartment": "compartment_7660", "id": "reaction_10764386", "reactome": "R-SCE-77090", "name": "Methylation of GMP-cap by RNA Methyltransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764379", "species_77087" ], "products": [ "species_10762304", "species_10764383", "species_10764352", "species_10763293", "species_77502" ], "modifiers": [ [ "species_10764379", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P32783", "YBR236C", "Q01159", "YGL130W", "YML010W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764388": { "compartment": "compartment_7660", "id": "reaction_10764388", "reactome": "R-SCE-77094", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762228", "species_10762223" ], "products": [ "species_10762230" ], "modifiers": [], "additional_components": [ "YMR125W", "YPL178W", "P34160", "YMR125W", "Q08920", "YPL178W" ] }, "reaction_10764356": { "compartment": "compartment_7660", "id": "reaction_10764356", "reactome": "R-SCE-77073", "name": "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764330", "species_10764352", "species_10764346" ], "products": [ "species_10764354" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q01159", "YGL130W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "YML010W", "YBR236C", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764372": { "compartment": "compartment_7660", "id": "reaction_10764372", "reactome": "R-SCE-77081", "name": "Formation of the CE:GMP intermediate complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113571", "species_10764362" ], "products": [ "species_111349", "species_10764369" ], "modifiers": [ [ "species_10764362", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "species_113578", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q01159", "YGL130W", "Q02939", "YPL122C", "P22139", "RPB10", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P32783", "YBR236C", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3" ] }, "reaction_10764390": { "compartment": "compartment_7660", "id": "reaction_10764390", "reactome": "R-SCE-77095", "name": "Recognition and binding of the mRNA cap by the cap-binding complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762304", "species_10762230" ], "products": [ "species_10762306" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P34160", "YMR125W", "Q08920", "YPL178W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764820": { "compartment": "compartment_7660", "id": "reaction_10764820", "reactome": "R-SCE-110322", "name": "Formation of Pol zeta complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764773", "species_10764778" ], "products": [ "species_10764780" ], "modifiers": [], "additional_components": [ "YPL167C", "YIL139C", "P38927", "YIL139C", "P14284", "YPL167C" ] }, "reaction_10764789": { "compartment": "compartment_7660", "id": "reaction_10764789", "reactome": "R-SCE-110311", "name": "POLZ extends translesion synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764782", "species_30555" ], "products": [ "species_10764780", "species_10764786", "species_113541" ], "modifiers": [ [ "species_10764782", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38927", "YIL139C", "P14284", "YPL167C", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C" ] }, "reaction_10778576": { "compartment": "compartment_7660", "id": "reaction_10778576", "reactome": "R-SCE-5656158", "name": "POLZ elongates POLI-incorporated dNMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778564", "species_30555" ], "products": [ "species_10764780", "species_113541", "species_10778573", "species_10764742" ], "modifiers": [ [ "species_10778564", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38927", "YIL139C", "P14284", "YPL167C", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_109496", "P38629", "YNL290W", "YOR346W", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C" ] }, "reaction_10778296": { "compartment": "compartment_7660", "id": "reaction_10778296", "reactome": "R-SCE-5652151", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764780", "species_10764765" ], "products": [ "species_10764782" ], "modifiers": [], "additional_components": [ "P38927", "YIL139C", "P14284", "YPL167C", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C" ] }, "reaction_10764759": { "compartment": "compartment_7660", "id": "reaction_10764759", "reactome": "R-SCE-110307", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764755", "species_10764742" ], "products": [ "species_10764757" ], "modifiers": [], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "YOR346W", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10778567": { "compartment": "compartment_7660", "id": "reaction_10778567", "reactome": "R-SCE-5656148", "name": "POLI incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10778558" ], "products": [ "species_10778564", "species_113541" ], "modifiers": [ [ "species_10778558", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C" ] }, "reaction_10778548": { "compartment": "compartment_7660", "id": "reaction_10778548", "reactome": "R-SCE-5655965", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10778536" ], "products": [ "species_10764780", "species_10778545", "species_113541", "species_10764742" ], "modifiers": [ [ "species_10778536", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527", "P38927", "YIL139C", "P14284", "YPL167C", "P38630", "YOR217W", "P40339", "YOL094C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527", "YOR346W", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527" ] }, "reaction_10764768": { "compartment": "compartment_7660", "id": "reaction_10764768", "reactome": "R-SCE-110308", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10764757" ], "products": [ "species_10764765" ], "modifiers": [ [ "species_10764757", "catalyst" ] ], "additional_components": [ "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P22336", "YAR007C", "P12689", "YOR346W", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W" ] }, "reaction_10778539": { "compartment": "compartment_7660", "id": "reaction_10778539", "reactome": "R-SCE-5655892", "name": "POLK incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10778530" ], "products": [ "species_10778536", "species_113541" ], "modifiers": [ [ "species_10778530", "catalyst" ] ], "additional_components": [ "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38927", "YIL139C", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P26754", "YNL312W", "P38927", "YIL139C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527", "P12689", "YOR346W", "P38630", "YOR217W", "P40339", "YOL094C", "P14284", "YPL167C", "species_109496", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38927", "YIL139C", "P26754", "YNL312W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "species_113527" ] }, "reaction_10773254": { "compartment": "compartment_70101", "id": "reaction_10773254", "reactome": "R-SCE-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_264618" ], "products": [ "species_29370", "species_1524071" ], "modifiers": [ [ "species_10773251", "catalyst" ] ], "additional_components": [ "P20485", "YLR133W", "Q03764", "YDR147W" ] }, "reaction_10773327": { "compartment": "compartment_12045", "id": "reaction_10773327", "reactome": "R-SCE-1483203", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_29372", "species_1500596" ], "modifiers": [ [ "species_10773324", "catalyst" ] ], "additional_components": [ "P32567", "YMR165C", "species_109496" ] }, "reaction_10773195": { "compartment": "compartment_12045", "id": "reaction_10773195", "reactome": "R-SCE-1482961", "name": "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524060", "species_1500596" ], "products": [ "species_109395", "species_426925" ], "modifiers": [ [ "species_10773192", "catalyst" ] ], "additional_components": [ "P17898", "YNL130C", "P22140", "YHR123W", "species_113527", "species_109496" ] }, "reaction_10773296": { "compartment": "compartment_12045", "id": "reaction_10773296", "reactome": "R-SCE-1483174", "name": "PE is methylated to PC by PEMT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_71284" ], "products": [ "species_426925", "species_71285" ], "modifiers": [ [ "species_10773293", "catalyst" ] ], "additional_components": [ "YJR073C" ] }, "reaction_10768148": { "compartment": "compartment_70101", "id": "reaction_10768148", "reactome": "R-SCE-264622", "name": "Cho is acetylated to AcCho by CHAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618", "species_76183" ], "products": [ "species_76194", "species_264643" ], "modifiers": [ [ "species_10768145", "catalyst" ] ], "additional_components": [ "YML042W" ] }, "reaction_10773219": { "compartment": "compartment_20699", "id": "reaction_10773219", "reactome": "R-SCE-1482973", "name": "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524057", "species_1524060" ], "products": [ "species_109395", "species_429785" ], "modifiers": [ [ "species_10773216", "catalyst" ] ], "additional_components": [ "P17898", "YNL130C", "P22140", "YHR123W", "species_113527", "species_109496" ] }, "reaction_10781570": { "compartment": "compartment_876", "id": "reaction_10781570", "reactome": "R-SCE-5694485", "name": "ABHD3 hydrolyses LPC(14:0) to 1AGPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694502", "species_29356" ], "products": [ "species_1861754", "species_5694457" ], "modifiers": [ [ "species_10781567", "catalyst" ] ], "additional_components": [ "Q03649", "YMR210W", "Q02891", "YPL095C", "P38295", "YBR177C" ] }, "reaction_10773273": { "compartment": "compartment_12045", "id": "reaction_10773273", "reactome": "R-SCE-1483081", "name": "PCho and CTP are condensed to CDP-Cho by PCYT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_1524071" ], "products": [ "species_111294", "species_1524060" ], "modifiers": [ [ "species_10773270", "catalyst" ] ], "additional_components": [ "P13259", "YGR202C" ] }, "reaction_10761101": { "compartment": "compartment_7660", "id": "reaction_10761101", "reactome": "R-SCE-69608", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761051", "species_29358" ], "products": [ "species_113582", "species_10761063" ], "modifiers": [ [ "species_10761098", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "YDL101C" ] }, "reaction_10761061": { "compartment": "compartment_70101", "id": "reaction_10761061", "reactome": "R-SCE-69600", "name": "Proteolytic degradation of ubiquitinated-Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761059" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P23748", "YMR036C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10761089": { "compartment": "compartment_7660", "id": "reaction_10761089", "reactome": "R-SCE-69604", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761051", "species_29358" ], "products": [ "species_113582", "species_10761063" ], "modifiers": [ [ "species_10761086", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "P36002", "YKL198C", "P47116", "YJR059W", "P06782", "YDR477W" ] }, "reaction_10765884": { "compartment": "compartment_947587", "id": "reaction_10765884", "reactome": "R-SCE-167415", "name": "G-protein alpha subunit is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764870", "species_29420" ], "products": [ "species_29438", "species_10764965" ], "modifiers": [ [ "species_10764864", "catalyst" ] ], "additional_components": [ "species_29438", "P10823", "YER020W", "species_29420", "P10823", "YER020W", "YER020W" ] }, "reaction_10777703": { "compartment": "compartment_12045", "id": "reaction_10777703", "reactome": "R-SCE-5362412", "name": "SYVN1 ubiquitinates Hh C-terminal fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777696", "species_10760634" ], "products": [ "species_10777700" ], "modifiers": [ [ "species_10777696", "catalyst" ] ], "additional_components": [ "P38307", "YBR201W", "Q05787", "YLR207W", "Q99220", "YDR057W", "Q08109", "YOL013C", "P25694", "YDL126C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38307", "YBR201W", "Q05787", "YLR207W", "Q99220", "YDR057W", "Q08109", "YOL013C", "P25694", "YDL126C", "P38307", "YBR201W", "Q05787", "YLR207W", "Q99220", "YDR057W", "Q08109", "YOL013C", "P25694", "YDL126C" ] }, "reaction_10777910": { "compartment": "compartment_5263232", "id": "reaction_10777910", "reactome": "R-SCE-5610749", "name": "cAMP dissociates PKA, promoting GLI processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10777906" ], "products": [ "species_10777900", "species_10777908" ], "modifiers": [], "additional_components": [ "P05986", "YKL166C", "P06245", "YPL203W", "P07278", "YIL033C", "P06244", "YJL164C", "P05986", "YKL166C", "P06245", "YPL203W", "P06244", "YJL164C", "P07278", "YIL033C", "species_30389" ] }, "reaction_10768868": { "compartment": "compartment_17947", "id": "reaction_10768868", "reactome": "R-SCE-382613", "name": "PEX-19 docks ABCD1/D2/D3 to peroximal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768844", "species_10768866" ], "products": [ "species_10768844", "species_10768836", "species_10768864" ], "modifiers": [], "additional_components": [ "YDR329C", "Q07418", "YDL065C", "P34230", "YKL188C", "P41909", "YPL147W", "YDR329C", "P34230", "YKL188C", "P41909", "YPL147W", "YDL065C" ] }, "reaction_10772903": { "compartment": "compartment_70101", "id": "reaction_10772903", "reactome": "R-SCE-1454916", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_1454930" ], "products": [ "species_29370", "species_1454919", "species_29372" ], "modifiers": [ [ "species_10772900", "catalyst" ] ], "additional_components": [ "P14772", "YLL015W", "P39109", "YDR135C", "P32386", "YLL048C", "P38735", "YHL035C", "P53049", "YGR281W", "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10768883": { "compartment": "compartment_876", "id": "reaction_10768883", "reactome": "R-SCE-383190", "name": "HCO3- transport through ion channel", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_29356" ], "products": [ "species_29370", "species_425425", "species_29372" ], "modifiers": [ [ "species_10768880", "catalyst" ] ], "additional_components": [ "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10786350": { "compartment": "compartment_876", "id": "reaction_10786350", "reactome": "R-SCE-8866851", "name": "CFTR transits to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786344" ], "products": [ "species_10768880" ], "modifiers": [], "additional_components": [ "P0CE68", "YKR103W", "P12866", "YKL209C", "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10768816": { "compartment": "compartment_70616", "id": "reaction_10768816", "reactome": "R-SCE-382560", "name": "ABC7, mABC1 and mABC2 mediate heme transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_189444", "species_113593" ], "products": [ "species_113548", "species_113581", "species_71185" ], "modifiers": [ [ "species_10768813", "catalyst" ] ], "additional_components": [ "P40416", "ATM1" ] }, "reaction_10786348": { "compartment": "compartment_70101", "id": "reaction_10786348", "reactome": "R-SCE-8866553", "name": "misfolded CFTR is degraded by the 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786346" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P0CE68", "YKR103W", "P12866", "YKL209C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10779080": { "compartment": "compartment_70101", "id": "reaction_10779080", "reactome": "R-SCE-5678863", "name": "CFTR transports Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_352022", "species_29356" ], "products": [ "species_29370", "species_188972", "species_29372" ], "modifiers": [ [ "species_10768880", "catalyst" ] ], "additional_components": [ "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10768839": { "compartment": "compartment_17947", "id": "reaction_10768839", "reactome": "R-SCE-382575", "name": "ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_382577", "species_113592", "species_29356" ], "products": [ "species_29370", "species_382571", "species_29372" ], "modifiers": [ [ "species_10768836", "catalyst" ] ], "additional_components": [ "P34230", "YKL188C", "P41909", "YPL147W" ] }, "reaction_10789057": { "compartment": "compartment_984", "id": "reaction_10789057", "reactome": "R-SCE-9673053", "name": "PM20D1 transforms oleoyl-phe from oleate and phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351993", "species_9673048" ], "products": [ "species_9673044", "species_109276" ], "modifiers": [ [ "species_10789054", "catalyst" ] ], "additional_components": [ "YJL172W" ] }, "reaction_10789059": { "compartment": "compartment_984", "id": "reaction_10789059", "reactome": "R-SCE-9673054", "name": "PM20D1 hydrolyzes oleoyl-phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9673044", "species_109276" ], "products": [ "species_351993", "species_9673048" ], "modifiers": [ [ "species_10789054", "catalyst" ] ], "additional_components": [ "YJL172W" ] }, "reaction_10784879": { "compartment": "compartment_20699", "id": "reaction_10784879", "reactome": "R-SCE-6811415", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784367", "species_10784862" ], "products": [ "species_10784864" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P01123", "YFL038C", "species_29438", "P47102", "YJR031C", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "species_29438" ] }, "reaction_10784874": { "compartment": "compartment_20699", "id": "reaction_10784874", "reactome": "R-SCE-6811412", "name": "Active ARF recruits coatomer to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784870", "species_10784438" ], "products": [ "species_10784872" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P43621", "YFR051C", "P53600", "YPL010W", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P41810", "YDR238C", "P47102", "YJR031C", "P11076", "YDL192W", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P41810", "YDR238C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W" ] }, "reaction_10784939": { "compartment": "compartment_20699", "id": "reaction_10784939", "reactome": "R-SCE-6811417", "name": "ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784935", "species_10784925", "species_10784872", "species_10784923", "species_10784463" ], "products": [ "species_10784937" ], "modifiers": [], "additional_components": [ "P18414", "YBL040C", "P38819", "YHR110W", "P32803", "YGL200C", "P53198", "YGL002W", "P53337", "YGR284C", "P54837", "YML012W", "Q05359", "YAR002C-A", "YLR268W", "P47102", "YJR031C", "P11076", "YDL192W", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P41810", "YDR238C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P38819", "YHR110W", "P32803", "YGL200C", "P53198", "YGL002W", "P39704", "YAL007C", "Q12403", "YDL018C", "P54837", "YML012W", "Q12450", "YOR016C", "Q05359", "YAR002C-A", "P32572", "YNL204C", "P38682", "YER122C", "P35197", "YDL226C", "P32803", "YGL200C", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P53337", "YGR284C", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P22214", "YLR268W", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C" ] }, "reaction_10784952": { "compartment": "compartment_20699", "id": "reaction_10784952", "reactome": "R-SCE-6811418", "name": "ARFGAPs stimulate ARF GTPase activity at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784937" ], "products": [ "species_10784949", "species_10784367", "species_10784463", "species_10784385" ], "modifiers": [ [ "species_10784937", "catalyst" ] ], "additional_components": [ "P32803", "YGL200C", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P53337", "YGR284C", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P22214", "YLR268W", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C", "P32803", "YGL200C", "P53198", "YGL002W", "P39704", "YAL007C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P22214", "YLR268W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P43621", "YFR051C", "P53337", "YGR284C", "P53600", "YPL010W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "Q12403", "YDL018C", "P32074", "YNL287W", "P41811", "YGL137W", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P32572", "YNL204C", "P38682", "YER122C", "P35197", "YDL226C", "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "P32803", "YGL200C", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P53337", "YGR284C", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P22214", "YLR268W", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C" ] }, "reaction_10784982": { "compartment": "compartment_12045", "id": "reaction_10784982", "reactome": "R-SCE-6811425", "name": "NSF and SNAPs bind cis-SNARE at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10784980" ], "products": [ "species_10784971" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P22214", "YLR268W", "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W" ] }, "reaction_10784974": { "compartment": "compartment_12045", "id": "reaction_10784974", "reactome": "R-SCE-6811422", "name": "NSF ATPase activity dissociates cis-SNARE at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10784971" ], "products": [ "species_10769994", "species_10781444", "species_10784957", "species_10784962", "species_10767816", "species_29372", "species_10784967" ], "modifiers": [ [ "species_10784971", "catalyst" ] ], "additional_components": [ "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W", "YBL050W", "P18759", "YBR080C", "YDR498C", "YOR075W", "YLR268W", "YGL098W", "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W" ] }, "reaction_10784868": { "compartment": "compartment_20699", "id": "reaction_10784868", "reactome": "R-SCE-6811411", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784864", "species_10784385" ], "products": [ "species_10784866" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "species_29438", "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "species_29420", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438" ] }, "reaction_10785080": { "compartment": "compartment_12045", "id": "reaction_10785080", "reactome": "R-SCE-6811427", "name": "COPI vesicle uncoating at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785078" ], "products": [ "species_10785076", "species_10784438", "species_10784980", "species_10785042", "species_10781345" ], "modifiers": [], "additional_components": [ "P32803", "YGL200C", "P53198", "YGL002W", "P39704", "YAL007C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P41810", "YDR238C", "P22214", "YLR268W", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P33891", "YGL145W", "P38819", "YHR110W", "P43621", "YFR051C", "P53146", "YGL098W", "P28791", "YDR498C", "P53337", "YGR284C", "P41834", "YOR075W", "P53600", "YPL010W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "Q12403", "YDL018C", "P53847", "YNL258C", "P32074", "YNL287W", "P41811", "YGL137W", "P18414", "YBL040C", "P38819", "YHR110W", "P32803", "YGL200C", "P53198", "YGL002W", "P53337", "YGR284C", "P54837", "YML012W", "Q05359", "YAR002C-A", "P43621", "YFR051C", "P53600", "YPL010W", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P41810", "YDR238C", "P53146", "YGL098W", "P28791", "YDR498C", "P41834", "YOR075W", "P22214", "YLR268W", "P38819", "YHR110W", "P32803", "YGL200C", "P53198", "YGL002W", "P39704", "YAL007C", "Q12403", "YDL018C", "P54837", "YML012W", "Q12450", "YOR016C", "Q05359", "YAR002C-A", "species_29420", "P01123", "YFL038C" ] }, "reaction_10784877": { "compartment": "compartment_20699", "id": "reaction_10784877", "reactome": "R-SCE-6811414", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10784866" ], "products": [ "species_10784870", "species_29420" ], "modifiers": [ [ "species_10784866", "catalyst" ] ], "additional_components": [ "species_29420", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "species_29420", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438" ] }, "reaction_10769704": { "compartment": "compartment_876", "id": "reaction_10769704", "reactome": "R-SCE-426130", "name": "SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113", "species_188972" ], "products": [ "species_83910", "species_352022" ], "modifiers": [ [ "species_10769701", "catalyst" ] ], "additional_components": [ "YBR235W" ] }, "reaction_10769699": { "compartment": "compartment_876", "id": "reaction_10769699", "reactome": "R-SCE-426086", "name": "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113", "species_188972", "species_74126" ], "products": [ "species_29804", "species_83910", "species_352022" ], "modifiers": [ [ "species_10769694", "catalyst" ] ], "additional_components": [ "YBR235W" ] }, "reaction_10774613": { "compartment": "compartment_70101", "id": "reaction_10774613", "reactome": "R-SCE-2534096", "name": "METAP1/2 demethylates GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774594" ], "products": [ "species_174390", "species_10774582" ], "modifiers": [ [ "species_10774610", "catalyst" ] ], "additional_components": [ "YER020W", "YER020W", "Q01662", "YLR244C", "P38174", "YBL091C", "species_880069" ] }, "reaction_10774654": { "compartment": "compartment_70101", "id": "reaction_10774654", "reactome": "R-SCE-2586748", "name": "GUCA binds Ca2+ to form GUCA:Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_10774640" ], "products": [ "species_10774652" ], "modifiers": [], "additional_components": [ "YDR373W", "species_74016", "Q06389", "YDR373W" ] }, "reaction_10774592": { "compartment": "compartment_70101", "id": "reaction_10774592", "reactome": "R-SCE-2534087", "name": "NMT1/2 transfer MYS to GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2534019", "species_10774582" ], "products": [ "species_76194", "species_10763522" ], "modifiers": [ [ "species_10774587", "catalyst" ] ], "additional_components": [ "YER020W", "YER020W", "YLR195C" ] }, "reaction_10763540": { "compartment": "compartment_2514888", "id": "reaction_10763540", "reactome": "R-SCE-74059", "name": "PDE6 hydrolyses cGMP to GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30991" ], "products": [ "species_113578" ], "modifiers": [ [ "species_10763537", "catalyst" ] ], "additional_components": [ "P06776", "YOR360C", "species_29438", "P10823", "YER020W" ] }, "reaction_10774322": { "compartment": "compartment_70101", "id": "reaction_10774322", "reactome": "R-SCE-2465940", "name": "atRAL is reduced to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_975622" ], "products": [ "species_29366", "species_2473607" ], "modifiers": [ [ "species_10774319", "catalyst" ] ], "additional_components": [ "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C" ] }, "reaction_10765352": { "compartment": "compartment_7660", "id": "reaction_10765352", "reactome": "R-SCE-156678", "name": "Activation of Cdc25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765340", "species_113592" ], "products": [ "species_29370", "species_10765343" ], "modifiers": [ [ "species_10765349", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "YMR001C" ] }, "reaction_10765477": { "compartment": "compartment_7660", "id": "reaction_10765477", "reactome": "R-SCE-162657", "name": "Inactivation of Myt1 kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10765469" ], "products": [ "species_113582", "species_10765472" ], "modifiers": [ [ "species_10765474", "catalyst" ] ], "additional_components": [ "YJL187C", "YJL187C", "YMR001C" ] }, "reaction_10771316": { "compartment": "compartment_70101", "id": "reaction_10771316", "reactome": "R-SCE-893616", "name": "glutamine + pyruvate => 2-oxoglutaramate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29398" ], "products": [ "species_893598", "species_29432" ], "modifiers": [ [ "species_10771307", "catalyst" ] ], "additional_components": [ "P47039", "YJL060W" ] }, "reaction_10781888": { "compartment": "compartment_5460", "id": "reaction_10781888", "reactome": "R-SCE-6783939", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113529", "species_113590" ], "products": [ "species_379717", "species_113526" ], "modifiers": [ [ "species_10781885", "catalyst" ] ], "additional_components": [ "P32263", "YER023W" ] }, "reaction_10761570": { "compartment": "compartment_5460", "id": "reaction_10761570", "reactome": "R-SCE-70664", "name": "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113529", "species_113590" ], "products": [ "species_379717", "species_113526" ], "modifiers": [ [ "species_10761567", "catalyst" ] ], "additional_components": [ "P32263", "YER023W" ] }, "reaction_10761572": { "compartment": "compartment_5460", "id": "reaction_10761572", "reactome": "R-SCE-70666", "name": "glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31339", "species_113552" ], "products": [ "species_113594", "species_113585" ], "modifiers": [ [ "species_10761557", "catalyst" ] ], "additional_components": [ "P07991", "YLR438W" ] }, "reaction_10771117": { "compartment": "compartment_5460", "id": "reaction_10771117", "reactome": "R-SCE-508040", "name": "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_113552", "species_113529", "species_113593" ], "products": [ "species_31339", "species_113548", "species_113563", "species_113581" ], "modifiers": [ [ "species_10771114", "catalyst" ] ], "additional_components": [ "P54885", "YOR323C" ] }, "reaction_10781895": { "compartment": "compartment_70101", "id": "reaction_10781895", "reactome": "R-SCE-6783955", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_35305" ], "products": [ "species_29366", "species_113538" ], "modifiers": [ [ "species_10781892", "catalyst" ] ], "additional_components": [ "P32263", "YER023W" ] }, "reaction_10761527": { "compartment": "compartment_70101", "id": "reaction_10761527", "reactome": "R-SCE-70606", "name": "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_31633" ], "products": [ "species_29370", "species_29472", "species_29372" ], "modifiers": [ [ "species_10761524", "catalyst" ] ], "additional_components": [ "P32288", "YPR035W" ] }, "reaction_10761529": { "compartment": "compartment_5460", "id": "reaction_10761529", "reactome": "R-SCE-70613", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113587" ], "products": [ "species_113594", "species_113553" ], "modifiers": [ [ "species_10761497", "catalyst" ] ], "additional_components": [ "Q01802", "YKL106W" ] }, "reaction_10789049": { "compartment": "compartment_7660", "id": "reaction_10789049", "reactome": "R-SCE-9671145", "name": "DKC1 binds SHQ1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765537", "species_10789045" ], "products": [ "species_10789047" ], "modifiers": [], "additional_components": [ "YLR175W", "YIL104C", "P33322", "YLR175W", "P40486", "YIL104C" ] }, "reaction_10769750": { "compartment": "compartment_876", "id": "reaction_10769750", "reactome": "R-SCE-427555", "name": "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648", "species_351626" ], "products": [ "species_70106", "species_174375" ], "modifiers": [ [ "species_10769747", "catalyst" ] ], "additional_components": [ "P53394", "YPR003C" ] }, "reaction_10766300": { "compartment": "compartment_70101", "id": "reaction_10766300", "reactome": "R-SCE-174392", "name": "PAPSS1,2 transfer SO4(2-) group to ATP to form APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174375", "species_113592" ], "products": [ "species_174370", "species_111294" ], "modifiers": [ [ "species_10766269", "catalyst" ] ], "additional_components": [ "YKL001C" ] }, "reaction_10766274": { "compartment": "compartment_70101", "id": "reaction_10766274", "reactome": "R-SCE-174389", "name": "PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174370", "species_113592" ], "products": [ "species_158471", "species_29370" ], "modifiers": [ [ "species_10766269", "catalyst" ] ], "additional_components": [ "YKL001C" ] }, "reaction_10778591": { "compartment": "compartment_7660", "id": "reaction_10778591", "reactome": "R-SCE-5661121", "name": "KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778271", "species_113671", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776818" ], "modifiers": [ [ "species_10776825", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YBR112C" ] }, "reaction_10778580": { "compartment": "compartment_7660", "id": "reaction_10778580", "reactome": "R-SCE-5661116", "name": "KDM5A-D demethylate Me3K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777406", "species_113671", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776782" ], "modifiers": [ [ "species_10776810", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03214", "YMR176W", "P47156", "YJR119C" ] }, "reaction_10775027": { "compartment": "compartment_7660", "id": "reaction_10775027", "reactome": "R-SCE-3214912", "name": "KDM1A, KDM1B demethylate MeK5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775017" ], "products": [ "species_10775019", "species_29478" ], "modifiers": [ [ "species_10775024", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YMR020W" ] }, "reaction_10778578": { "compartment": "compartment_7660", "id": "reaction_10778578", "reactome": "R-SCE-5661114", "name": "KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10778230", "species_113685" ], "products": [ "species_10776742", "species_159942", "species_159939", "species_29478" ], "modifiers": [ [ "species_10776754", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03833", "YDR096W", "P39956", "YER169W" ] }, "reaction_10778589": { "compartment": "compartment_7660", "id": "reaction_10778589", "reactome": "R-SCE-5661120", "name": "KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10776843", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776759" ], "modifiers": [ [ "species_10776777", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03833", "YDR096W", "P39956", "YER169W" ] }, "reaction_10776757": { "compartment": "compartment_7660", "id": "reaction_10776757", "reactome": "R-SCE-4722133", "name": "KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776742", "species_113671", "species_113685" ], "products": [ "species_10775019", "species_159942", "species_159939", "species_29478" ], "modifiers": [ [ "species_10776754", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03833", "YDR096W", "P39956", "YER169W" ] }, "reaction_10776780": { "compartment": "compartment_7660", "id": "reaction_10776780", "reactome": "R-SCE-4724279", "name": "KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10776759", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776761" ], "modifiers": [ [ "species_10776777", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03833", "YDR096W", "P39956", "YER169W" ] }, "reaction_10776813": { "compartment": "compartment_7660", "id": "reaction_10776813", "reactome": "R-SCE-4754181", "name": "KDM5A-D demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10776782" ], "products": [ "species_159942", "species_10775017", "species_159939", "species_29478" ], "modifiers": [ [ "species_10776810", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "Q03214", "YMR176W", "P47156", "YJR119C" ] }, "reaction_10778593": { "compartment": "compartment_7660", "id": "reaction_10778593", "reactome": "R-SCE-5661123", "name": "KDM1A, KDM1B demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776782" ], "products": [ "species_10775017", "species_29478" ], "modifiers": [ [ "species_10775024", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YMR020W" ] }, "reaction_10776830": { "compartment": "compartment_7660", "id": "reaction_10776830", "reactome": "R-SCE-4754187", "name": "KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10776818", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10776823" ], "modifiers": [ [ "species_10776825", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YBR112C" ] }, "reaction_10770574": { "compartment": "compartment_7660", "id": "reaction_10770574", "reactome": "R-SCE-448955", "name": "Phosphorylation of MEF2 proteins by p38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10770541", "species_10770545" ], "products": [ "species_113582", "species_10770571" ], "modifiers": [ [ "species_10770545", "catalyst" ] ], "additional_components": [ "P38128", "YBR182C", "Q12224", "YPL089C", "P32485", "YLR113W", "P32485", "YLR113W", "P38128", "YBR182C", "Q12224", "YPL089C", "P32485", "YLR113W" ] }, "reaction_10769182": { "compartment": "compartment_17940", "id": "reaction_10769182", "reactome": "R-SCE-392749", "name": "Transport of L1 into endosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769180" ], "products": [ "species_10769180" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C" ] }, "reaction_10770284": { "compartment": "compartment_70101", "id": "reaction_10770284", "reactome": "R-SCE-445079", "name": "Phosphorylation of L1 by ERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10769180", "species_10764614" ], "products": [ "species_29370", "species_10770282" ], "modifiers": [ [ "species_10764614", "catalyst" ] ], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "YBL016W", "P16892", "YBL016W", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "YBL016W" ] }, "reaction_10764609": { "compartment": "compartment_70101", "id": "reaction_10764609", "reactome": "R-SCE-109860", "name": "MAP2K1 phosphorylates MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10764572" ], "products": [ "species_29370", "species_10764600" ], "modifiers": [ [ "species_10764572", "catalyst" ], [ "species_10764605", "inhibitor" ] ], "additional_components": [ "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "YDL159W" ] }, "reaction_10767247": { "compartment": "compartment_7660", "id": "reaction_10767247", "reactome": "R-SCE-198756", "name": "ERK1/2 phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767221", "species_29358" ], "products": [ "species_113582", "species_10767227" ], "modifiers": [ [ "species_10767244", "catalyst" ] ], "additional_components": [ "YBR028C", "YBR028C", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10764619": { "compartment": "compartment_70101", "id": "reaction_10764619", "reactome": "R-SCE-109862", "name": "MAP2K2 phosphorylates MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764582", "species_113592" ], "products": [ "species_29370", "species_10764616" ], "modifiers": [ [ "species_10764582", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "P06784", "YDL159W", "P16892", "YBL016W", "P06784", "YDL159W", "P16892", "YBL016W", "P06784", "YDL159W" ] }, "reaction_10766423": { "compartment": "compartment_7660", "id": "reaction_10766423", "reactome": "R-SCE-176956", "name": "Formation of GINS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766419", "species_10766414", "species_10766404", "species_10766409" ], "products": [ "species_10766421" ], "modifiers": [], "additional_components": [ "YDR489W", "YOL146W", "YDR013W", "YJL072C", "Q12488", "YDR013W", "Q03406", "YDR489W", "P40359", "YJL072C", "Q12146", "YOL146W" ] }, "reaction_10787208": { "compartment": "compartment_12045", "id": "reaction_10787208", "reactome": "R-SCE-8941701", "name": "UGT1A10 transfers GlcA from UDP-GlcA to GCTN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8941723", "species_174384" ], "products": [ "species_158602", "species_8941725" ], "modifiers": [ [ "species_10765445", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10772692": { "compartment": "compartment_70101", "id": "reaction_10772692", "reactome": "R-SCE-1247910", "name": "CNDP2:2Mn2+ dimer hydrolyses CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1247904", "species_29356" ], "products": [ "species_29424", "species_111707" ], "modifiers": [ [ "species_10772689", "catalyst" ] ], "additional_components": [ "species_113527", "P43616", "YFR044C" ] }, "reaction_10788717": { "compartment": "compartment_17957", "id": "reaction_10788717", "reactome": "R-SCE-9632038", "name": "UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159160", "species_174384" ], "products": [ "species_158602", "species_159149" ], "modifiers": [ [ "species_10788714", "catalyst" ] ], "additional_components": [ "Q06321", "YLR189C" ] }, "reaction_10765464": { "compartment": "compartment_17957", "id": "reaction_10765464", "reactome": "R-SCE-159194", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159151", "species_174384" ], "products": [ "species_159160", "species_158602" ], "modifiers": [ [ "species_10765459", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10766342": { "compartment": "compartment_17957", "id": "reaction_10766342", "reactome": "R-SCE-174916", "name": "Formation of N-glucuronides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174384", "species_174932" ], "products": [ "species_158602", "species_174918" ], "modifiers": [ [ "species_10765459", "catalyst" ] ], "additional_components": [ "CHEBI:41774", "CHEBI:17688", "CHEBI:32663", "CHEBI:63860", "YLR189C" ] }, "reaction_10766297": { "compartment": "compartment_70101", "id": "reaction_10766297", "reactome": "R-SCE-174391", "name": "MAT1A multimers transfer Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_174390", "species_29356" ], "products": [ "species_111294", "species_71284", "species_29372" ], "modifiers": [ [ "species_10766294", "catalyst" ] ], "additional_components": [ "P19358", "YDR502C", "species_74126", "species_109496", "P10659", "YLR180W" ] }, "reaction_10765462": { "compartment": "compartment_17957", "id": "reaction_10765462", "reactome": "R-SCE-159179", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159160", "species_174384" ], "products": [ "species_158602", "species_159149" ], "modifiers": [ [ "species_10765459", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10766310": { "compartment": "compartment_70101", "id": "reaction_10766310", "reactome": "R-SCE-174394", "name": "GSS:Mg2+ dimer synthesizes GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_174393", "species_113592" ], "products": [ "species_29370", "species_29450", "species_29372" ], "modifiers": [ [ "species_10766307", "catalyst" ], [ "species_29450", "inhibitor" ] ], "additional_components": [ "Q08220", "YOL049W", "species_109496" ] }, "reaction_10766322": { "compartment": "compartment_70101", "id": "reaction_10766322", "reactome": "R-SCE-174401", "name": "AHCY:NAD+ tetramer hydrolyses AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71285", "species_29356" ], "products": [ "species_174369", "species_83909" ], "modifiers": [ [ "species_10766319", "catalyst" ] ], "additional_components": [ "P39954", "YER043C", "species_113526" ] }, "reaction_10787391": { "compartment": "compartment_876", "id": "reaction_10787391", "reactome": "R-SCE-8943279", "name": "GGT dimers hydrolyse GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1247892", "species_109276" ], "products": [ "species_210382", "species_1247934" ], "modifiers": [ [ "species_10777790", "catalyst" ] ], "additional_components": [ "Q05902", "YLR299W" ] }, "reaction_10781250": { "compartment": "compartment_17957", "id": "reaction_10781250", "reactome": "R-SCE-5693724", "name": "ESD dimer hydrolyses S-FGSH to GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_5693723" ], "products": [ "species_158543", "species_194712" ], "modifiers": [ [ "species_10781247", "catalyst" ] ], "additional_components": [ "P40363", "YJL068C" ] }, "reaction_10783821": { "compartment": "compartment_70101", "id": "reaction_10783821", "reactome": "R-SCE-6800149", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6806829", "species_71284" ], "products": [ "species_6800127", "species_71285" ], "modifiers": [ [ "species_10783815", "catalyst" ] ], "additional_components": [ "P53738", "TRM112", "Q03920", "YDR140W" ] }, "reaction_10772702": { "compartment": "compartment_70101", "id": "reaction_10772702", "reactome": "R-SCE-1247935", "name": "OPLAH hydrolyses OPRO to L-Glu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1247942", "species_29356" ], "products": [ "species_29370", "species_29404", "species_29372" ], "modifiers": [ [ "species_10772699", "catalyst" ] ], "additional_components": [ "P28273", "YKL215C" ] }, "reaction_10788719": { "compartment": "compartment_17957", "id": "reaction_10788719", "reactome": "R-SCE-9632039", "name": "UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159151", "species_174384" ], "products": [ "species_159160", "species_158602" ], "modifiers": [ [ "species_10765441", "catalyst" ] ], "additional_components": [ "YLR189C" ] }, "reaction_10761138": { "compartment": "compartment_70101", "id": "reaction_10761138", "reactome": "R-SCE-70286", "name": "UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29494", "species_29548" ], "products": [ "species_29410", "species_111294" ], "modifiers": [ [ "species_10761135", "catalyst" ] ], "additional_components": [ "P32861", "YKL035W" ] }, "reaction_10781969": { "compartment": "compartment_70101", "id": "reaction_10781969", "reactome": "R-SCE-6785928", "name": "CHAC1,2 cleaves GSH to OPRO and CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450" ], "products": [ "species_1247904", "species_1247942" ], "modifiers": [ [ "species_10781964", "catalyst" ] ], "additional_components": [ "YER163C" ] }, "reaction_10778676": { "compartment": "compartment_70101", "id": "reaction_10778676", "reactome": "R-SCE-5668545", "name": "NIK autophosphorylates on T559", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769138", "species_113592" ], "products": [ "species_29370", "species_10778673" ], "modifiers": [ [ "species_10769138", "catalyst" ] ], "additional_components": [ "YCR073C", "YCR073C", "YCR073C" ] }, "reaction_10778670": { "compartment": "compartment_70101", "id": "reaction_10778670", "reactome": "R-SCE-5668520", "name": "26Sproteasome degrades K48polyUb-NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778668" ], "products": [], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "YCR073C", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10784295": { "compartment": "compartment_70101", "id": "reaction_10784295", "reactome": "R-SCE-6805811", "name": "Release of SEPT4 from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784279" ], "products": [ "species_10784293" ], "modifiers": [], "additional_components": [ "P32457", "YLR314C", "Q07657", "YDL225W", "Q04921", "YDR218C", "P32468", "YHR107C", "P41901", "YGR059W", "P32458", "YJR076C", "P32457", "YLR314C", "Q07657", "YDL225W", "Q04921", "YDR218C", "P32468", "YHR107C", "P41901", "YGR059W", "P32458", "YJR076C" ] }, "reaction_10765222": { "compartment": "compartment_17906", "id": "reaction_10765222", "reactome": "R-SCE-114284", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765220" ], "products": [ "species_10765214" ], "modifiers": [], "additional_components": [ "P00045", "YEL039C", "P00044", "YJR048W", "P00045", "YEL039C", "P00044", "YJR048W" ] }, "reaction_10764147": { "compartment": "compartment_7660", "id": "reaction_10764147", "reactome": "R-SCE-75891", "name": "Abortive Initiation After Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764145" ], "products": [ "species_10763503", "species_75897", "species_10763293", "species_10762312" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P36100", "YKL028W", "P22139", "RPB10", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P06839", "RAD3", "P36100", "YKL028W", "P36145", "YKR062W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10764072": { "compartment": "compartment_7660", "id": "reaction_10764072", "reactome": "R-SCE-75862", "name": "Fall Back to Closed Pre-initiation Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764062" ], "products": [ "species_10764070" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "P38902", "YOL005C", "Q05021", "YMR227C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P22139", "RPB10", "P46677", "YGR274C", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3" ] }, "reaction_10765186": { "compartment": "compartment_7660", "id": "reaction_10765186", "reactome": "R-SCE-112434", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764352", "species_10764976" ], "products": [ "species_10764978" ], "modifiers": [], "additional_components": [ "YML010W", "YGR063C", "P27692", "YML010W", "P32914", "YGR063C" ] }, "reaction_10765190": { "compartment": "compartment_7660", "id": "reaction_10765190", "reactome": "R-SCE-113409", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765001" ], "products": [ "species_10765001" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P27692", "YML010W", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P32914", "YGR063C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10", "P41896", "YGR005C", "P20434", "RPB5", "P27692", "YML010W", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P32914", "YGR063C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10763507": { "compartment": "compartment_7660", "id": "reaction_10763507", "reactome": "R-SCE-73946", "name": "Abortive initiation after formation of the first phosphodiester bond", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763505" ], "products": [ "species_109877", "species_10763503", "species_10763491", "species_10763293", "species_10762312", "species_10763417", "species_10763422" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P36100", "YKL028W", "P36145", "YKR062W", "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P32774", "YKL058W", "P32773", "YOR194C", "YPR086W" ] }, "reaction_10764060": { "compartment": "compartment_7660", "id": "reaction_10764060", "reactome": "R-SCE-75856", "name": "Abortive Initiation Before Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764058" ], "products": [ "species_110068", "species_10763503", "species_10763491", "species_10763293", "species_10762312", "species_10763417", "species_10763422" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "Q12030", "YDR167W", "P20435", "RPO26", "Q05021", "YMR227C", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q03761", "YDR145W", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P38129", "YBR198C", "P36100", "YKL028W", "P50105", "YMR005W", "P46677", "YGR274C", "P22139", "RPB10", "P32773", "YOR194C", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P23255", "YCR042C", "P32774", "YKL058W", "P32776", "YDR311W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P06839", "RAD3", "P36100", "YKL028W", "P36145", "YKR062W", "Q04226", "YML015C", "Q05027", "YMR236W", "Q12030", "YDR167W", "P38129", "YBR198C", "P23255", "YCR042C", "Q05021", "YMR227C", "P50105", "YMR005W", "P53040", "YGL112C", "P46677", "YGR274C", "P11747", "YML098W", "Q03761", "YDR145W", "P13393", "SPT15", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P32774", "YKL058W", "P32773", "YOR194C", "YPR086W" ] }, "reaction_10765192": { "compartment": "compartment_7660", "id": "reaction_10765192", "reactome": "R-SCE-113411", "name": "2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765164" ], "products": [ "species_10765168" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765184": { "compartment": "compartment_7660", "id": "reaction_10765184", "reactome": "R-SCE-112430", "name": "Formation of P-TEFb complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765028", "species_10765006" ], "products": [ "species_10765030" ], "modifiers": [], "additional_components": [ "Q05949", "YLR226W", "P46962", "YJL006C", "YKL139W", "Q05949", "YLR226W", "Q03957", "YKL139W", "P46962", "YJL006C" ] }, "reaction_10765170": { "compartment": "compartment_7660", "id": "reaction_10765170", "reactome": "R-SCE-112392", "name": "Resumption of elongation after recovery from pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765168" ], "products": [ "species_10765164" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765198": { "compartment": "compartment_7660", "id": "reaction_10765198", "reactome": "R-SCE-113414", "name": "7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765164" ], "products": [ "species_10765164" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765182": { "compartment": "compartment_7660", "id": "reaction_10765182", "reactome": "R-SCE-112429", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765097", "species_10765092" ], "products": [ "species_10765099" ], "modifiers": [], "additional_components": [ "YGL207W", "YML069W", "P32558", "YGL207W", "Q04636", "YML069W" ] }, "reaction_10765174": { "compartment": "compartment_7660", "id": "reaction_10765174", "reactome": "R-SCE-112395", "name": "Abortive termination of elongation after arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765164" ], "products": [ "species_10765172" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765196": { "compartment": "compartment_7660", "id": "reaction_10765196", "reactome": "R-SCE-113413", "name": "TFIIS-mediated recovery of elongation from arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765164" ], "products": [ "species_10765164" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10761589": { "compartment": "compartment_70101", "id": "reaction_10761589", "reactome": "R-SCE-70692", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498" ], "products": [ "species_29610", "species_113528" ], "modifiers": [ [ "species_10761586", "catalyst" ] ], "additional_components": [ "YKL184W" ] }, "reaction_10768335": { "compartment": "compartment_70101", "id": "reaction_10768335", "reactome": "R-SCE-350598", "name": "Arginine<=>Agmatine+CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468" ], "products": [ "species_113528", "species_351164" ], "modifiers": [ [ "species_10768332", "catalyst" ] ], "additional_components": [ "YKL184W" ] }, "reaction_10768411": { "compartment": "compartment_70101", "id": "reaction_10768411", "reactome": "R-SCE-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353113", "species_29610" ], "products": [ "species_353106", "species_204635" ], "modifiers": [ [ "species_10768408", "catalyst" ] ], "additional_components": [ "YPR069C" ] }, "reaction_10768403": { "compartment": "compartment_70101", "id": "reaction_10768403", "reactome": "R-SCE-351208", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_204635", "species_76183" ], "products": [ "species_76194", "species_353555" ], "modifiers": [ [ "species_10768398", "catalyst" ] ], "additional_components": [ "Q06592", "YPR193C", "P39979", "YEL066W" ] }, "reaction_10768419": { "compartment": "compartment_70101", "id": "reaction_10768419", "reactome": "R-SCE-351222", "name": "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284" ], "products": [ "species_353113", "species_113528" ], "modifiers": [ [ "species_10768416", "catalyst" ] ], "additional_components": [ "YOL052C" ] }, "reaction_10768401": { "compartment": "compartment_70101", "id": "reaction_10768401", "reactome": "R-SCE-351207", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353560", "species_76183" ], "products": [ "species_76194", "species_353575" ], "modifiers": [ [ "species_10768398", "catalyst" ] ], "additional_components": [ "Q06592", "YPR193C", "P39979", "YEL066W" ] }, "reaction_10778699": { "compartment": "compartment_70101", "id": "reaction_10778699", "reactome": "R-SCE-5671737", "name": "p-T774-PKN1 binds CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765340", "species_10778027" ], "products": [ "species_10778697" ], "modifiers": [], "additional_components": [ "YMR036C", "YBL105C", "P23748", "YMR036C", "P24583", "YBL105C" ] }, "reaction_10778693": { "compartment": "compartment_70101", "id": "reaction_10778693", "reactome": "R-SCE-5668932", "name": "PAK2 phosphorylates myosin regulatory light chain (MRLC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778684", "species_113592" ], "products": [ "species_29370", "species_10778690" ], "modifiers": [ [ "species_10778151", "catalyst" ] ], "additional_components": [ "P08964", "YHR023W", "Q06580", "YPR188C", "P53141", "YGL106W", "P08964", "YHR023W", "Q06580", "YPR188C", "P53141", "YGL106W", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W" ] }, "reaction_10778117": { "compartment": "compartment_70101", "id": "reaction_10778117", "reactome": "R-SCE-5626469", "name": "GTP-bound RAC1 and CDC42 bind IQGAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778113", "species_10768894" ], "products": [ "species_10778115" ], "modifiers": [], "additional_components": [ "Q12280", "YPL242C", "species_29438", "P19073", "YLR229C", "Q12280", "YPL242C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10778702": { "compartment": "compartment_70101", "id": "reaction_10778702", "reactome": "R-SCE-5671749", "name": "p-T774-PKN1 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778697", "species_113592" ], "products": [ "species_29370", "species_10763798", "species_10778027" ], "modifiers": [ [ "species_10778697", "catalyst" ] ], "additional_components": [ "P23748", "YMR036C", "P24583", "YBL105C", "YMR036C", "YBL105C", "P23748", "YMR036C", "P24583", "YBL105C" ] }, "reaction_10778091": { "compartment": "compartment_7660", "id": "reaction_10778091", "reactome": "R-SCE-5625797", "name": "KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10778076" ], "products": [ "species_159942", "species_159939", "species_10776769", "species_29478", "species_10778088" ], "modifiers": [ [ "species_10778076", "catalyst" ] ], "additional_components": [ "Q03833", "YDR096W", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P39956", "YER169W", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "Q03833", "YDR096W", "P39956", "YER169W", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "Q03833", "YDR096W", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P39956", "YER169W", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117" ] }, "reaction_10778074": { "compartment": "compartment_7660", "id": "reaction_10778074", "reactome": "R-SCE-5625784", "name": "PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778057", "species_29358" ], "products": [ "species_113582", "species_10778071" ], "modifiers": [ [ "species_10778057", "catalyst" ] ], "additional_components": [ "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117" ] }, "reaction_10778123": { "compartment": "compartment_70101", "id": "reaction_10778123", "reactome": "R-SCE-5626507", "name": "IQGAPs bind F-actin, which is inhibited by calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778115", "species_10773881" ], "products": [ "species_10778119" ], "modifiers": [ [ "species_10778121", "inhibitor" ] ], "additional_components": [ "Q12280", "YPL242C", "species_29438", "P19073", "YLR229C", "P60010", "YFL039C", "species_113592", "P60010", "YFL039C", "Q12280", "YPL242C", "species_113592", "species_29438", "P19073", "YLR229C", "P06787", "YBR109C", "Q12280", "YPL242C", "species_74016", "species_29438", "P19073", "YLR229C" ] }, "reaction_10778078": { "compartment": "compartment_7660", "id": "reaction_10778078", "reactome": "R-SCE-5625796", "name": "Demethylase KDM4C binds KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778071", "species_10776769" ], "products": [ "species_10778076" ], "modifiers": [], "additional_components": [ "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117", "Q03833", "YDR096W", "P39956", "YER169W", "Q03833", "YDR096W", "species_193079", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "species_193057", "P39956", "YER169W", "P02294", "YBL002W", "P02309", "YBR009C", "species_469662", "P24583", "YBL105C", "P36012", "YKL049C", "Q12692", "YOL012C", "P61830", "YBR010W", "CHEBI:29117" ] }, "reaction_10787831": { "compartment": "compartment_70101", "id": "reaction_10787831", "reactome": "R-SCE-8981931", "name": "RAC1 and CDC42 activate PAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768988", "species_10768894" ], "products": [ "species_10768986", "species_10778133" ], "modifiers": [], "additional_components": [ "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "P48562", "YNL298W", "Q03497", "YHL007C", "species_29438", "Q12469", "YOL113W", "P19073", "YLR229C" ] }, "reaction_10778020": { "compartment": "compartment_876", "id": "reaction_10778020", "reactome": "R-SCE-5623622", "name": "RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778012", "species_10769305" ], "products": [ "species_10778018" ], "modifiers": [], "additional_components": [ "YBL105C", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_29438" ] }, "reaction_10778160": { "compartment": "compartment_70101", "id": "reaction_10778160", "reactome": "R-SCE-5627775", "name": "Autophosphorylation of PAK1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10778137" ], "products": [ "species_29370", "species_10778157", "species_10768894" ], "modifiers": [ [ "species_10778137", "catalyst" ] ], "additional_components": [ "P48562", "YNL298W", "Q03497", "YHL007C", "species_29438", "Q12469", "YOL113W", "P19073", "YLR229C", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "Q03497", "YHL007C", "species_29438", "Q12469", "YOL113W", "P19073", "YLR229C" ] }, "reaction_10774032": { "compartment": "compartment_70101", "id": "reaction_10774032", "reactome": "R-SCE-2029456", "name": "RAC1 and CDC42 activate PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768972", "species_10768894" ], "products": [ "species_10768970", "species_10774023" ], "modifiers": [], "additional_components": [ "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C", "YHL007C", "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10787829": { "compartment": "compartment_70101", "id": "reaction_10787829", "reactome": "R-SCE-8981926", "name": "RAC1 and CDC42 activate PAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768992", "species_10768894" ], "products": [ "species_10768990", "species_10778135" ], "modifiers": [], "additional_components": [ "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C", "YHL007C", "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C" ] }, "reaction_10778126": { "compartment": "compartment_876", "id": "reaction_10778126", "reactome": "R-SCE-5626549", "name": "IQGAPs bind CALM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778115", "species_10767596" ], "products": [ "species_10778121" ], "modifiers": [], "additional_components": [ "Q12280", "YPL242C", "species_29438", "P19073", "YLR229C", "P06787", "YBR109C", "species_74016", "P06787", "YBR109C", "Q12280", "YPL242C", "species_74016", "species_29438", "P19073", "YLR229C" ] }, "reaction_10788712": { "compartment": "compartment_70101", "id": "reaction_10788712", "reactome": "R-SCE-9626817", "name": "PKC phosphorylates NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10788701" ], "products": [ "species_10788710", "species_29370" ], "modifiers": [ [ "species_10777257", "catalyst" ] ], "additional_components": [ "P29366", "YBR200W", "P22696", "YJR017C", "P29366", "YBR200W", "P22696", "YJR017C", "YBL105C" ] }, "reaction_10774058": { "compartment": "compartment_70101", "id": "reaction_10774058", "reactome": "R-SCE-2029473", "name": "Branching and elongation of mother and daughter filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774056", "species_10767714" ], "products": [ "species_10773926" ], "modifiers": [], "additional_components": [ "P60010", "YFL039C", "P40518", "YIL062C", "P53731", "YNR035C", "species_29370", "species_113592", "P33204", "YKL013C", "P32381", "YDL029W", "P47117", "YJR065C", "P38328", "YBR234C", "Q05933", "YLR370C", "P60010", "YFL039C", "species_113592", "P40518", "YIL062C", "P60010", "YFL039C", "P53731", "YNR035C", "P33204", "YKL013C", "species_113592", "P32381", "YDL029W", "P47117", "YJR065C", "P38328", "YBR234C", "Q05933", "YLR370C" ] }, "reaction_10778036": { "compartment": "compartment_70101", "id": "reaction_10778036", "reactome": "R-SCE-5623667", "name": "PDPK1 phosphorylates PKN1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10778022" ], "products": [ "species_29370", "species_10764515", "species_10778027", "species_10769305" ], "modifiers": [ [ "species_10778022", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_179838", "species_29438", "Q12236", "YOL100W", "species_179838", "Q12236", "YOL100W", "YBL105C", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_179838", "species_29438", "Q12236", "YOL100W" ] }, "reaction_10782731": { "compartment": "compartment_1222693", "id": "reaction_10782731", "reactome": "R-SCE-6798174", "name": "PIK3C3:PIK3R4 phosphorylates PI to PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524165" ], "products": [ "species_29370", "species_1629751" ], "modifiers": [ [ "species_10782728", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W" ] }, "reaction_10778024": { "compartment": "compartment_876", "id": "reaction_10778024", "reactome": "R-SCE-5623632", "name": "RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764515", "species_10778018" ], "products": [ "species_10778022" ], "modifiers": [], "additional_components": [ "species_179838", "Q12236", "YOL100W", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_29438", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P24583", "YBL105C", "P06780", "YPR165W", "species_179838", "species_29438", "Q12236", "YOL100W" ] }, "reaction_10767642": { "compartment": "compartment_70101", "id": "reaction_10767642", "reactome": "R-SCE-202127", "name": "eNOS synthesizes NO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29468", "species_29368" ], "products": [ "species_29366", "species_202124", "species_29968" ], "modifiers": [ [ "species_10767639", "catalyst" ], [ "species_5693375", "inhibitor" ] ], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "species_29870", "species_113596", "P11792", "YHR205W" ] }, "reaction_10777290": { "compartment": "compartment_876", "id": "reaction_10777290", "reactome": "R-SCE-5218821", "name": "PDK1 phosphorylates PKC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10765240" ], "products": [ "species_29370", "species_10777257" ], "modifiers": [ [ "species_10764513", "catalyst" ] ], "additional_components": [ "YBL105C", "YBL105C", "YOL100W" ] }, "reaction_10777285": { "compartment": "compartment_70101", "id": "reaction_10777285", "reactome": "R-SCE-5218813", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_112275", "species_10777268" ], "products": [ "species_10777283" ], "modifiers": [], "additional_components": [ "YBL105C", "species_112275", "P24583", "YBL105C", "species_74016" ] }, "reaction_10774274": { "compartment": "compartment_876", "id": "reaction_10774274", "reactome": "R-SCE-2317314", "name": "AKT binds PDPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767085", "species_10764515" ], "products": [ "species_10767087" ], "modifiers": [], "additional_components": [ "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "species_179838", "Q12236", "YOL100W", "P12688", "YKL126W", "species_179838", "Q12236", "YOL100W", "P11792", "YHR205W" ] }, "reaction_10777281": { "compartment": "compartment_70101", "id": "reaction_10777281", "reactome": "R-SCE-5218805", "name": "PKC autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10777257" ], "products": [ "species_29370", "species_10777268" ], "modifiers": [ [ "species_10777257", "catalyst" ] ], "additional_components": [ "YBL105C", "YBL105C", "YBL105C" ] }, "reaction_10767108": { "compartment": "compartment_70101", "id": "reaction_10767108", "reactome": "R-SCE-198270", "name": "PDPK1 phosphorylates AKT at T308", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10767087" ], "products": [ "species_29370", "species_10764515", "species_10767105" ], "modifiers": [ [ "species_10767087", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "species_179838", "Q12236", "YOL100W", "P11792", "YHR205W", "species_179838", "Q12236", "YOL100W", "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "Q12236", "YOL100W", "P11792", "YHR205W" ] }, "reaction_10766460": { "compartment": "compartment_70101", "id": "reaction_10766460", "reactome": "R-SCE-187688", "name": "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10766440" ], "products": [ "species_29370", "species_10766447" ], "modifiers": [ [ "species_10766457", "catalyst" ] ], "additional_components": [ "YKL171W", "YKL171W", "P32485", "YLR113W", "species_109496" ] }, "reaction_10767654": { "compartment": "compartment_70101", "id": "reaction_10767654", "reactome": "R-SCE-202137", "name": "AKT1 binds eNOS complex via HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767610", "species_10767095" ], "products": [ "species_10767618" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "P02829", "YPL240C", "species_74016", "species_73524", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "species_113596", "P12688", "YKL126W", "P11792", "YHR205W", "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_74016", "species_73524", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "P11792", "YHR205W", "species_113596" ] }, "reaction_10777296": { "compartment": "compartment_876", "id": "reaction_10777296", "reactome": "R-SCE-5218823", "name": "PKC phosphorylates sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10769088" ], "products": [ "species_29370", "species_10777293" ], "modifiers": [ [ "species_10777283", "catalyst" ] ], "additional_components": [ "YLR260W", "YLR260W", "species_112275", "P24583", "YBL105C", "species_74016" ] }, "reaction_10773346": { "compartment": "compartment_70101", "id": "reaction_10773346", "reactome": "R-SCE-1497784", "name": "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_10767635" ], "products": [ "species_10767639" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "species_29870", "P15108", "YMR186W", "species_113596", "P11792", "YHR205W", "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "species_29870", "species_113596", "P11792", "YHR205W" ] }, "reaction_10767637": { "compartment": "compartment_70101", "id": "reaction_10767637", "reactome": "R-SCE-202111", "name": "AKT1 phosphorylates eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767618", "species_113592" ], "products": [ "species_29370", "species_10767635" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_74016", "species_73524", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "P11792", "YHR205W", "species_113596", "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "species_29870", "P15108", "YMR186W", "species_113596", "P11792", "YHR205W" ] }, "reaction_10767219": { "compartment": "compartment_70101", "id": "reaction_10767219", "reactome": "R-SCE-198640", "name": "TORC2 (mTOR) phosphorylates AKT at S473", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767182", "species_113592" ], "products": [ "species_29370", "species_10767085" ], "modifiers": [ [ "species_10767216", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "Q08236", "YOL078W", "P32600", "YKL203C", "P41318", "YNL006W", "P40061", "YER093C", "P38346", "YBR270C", "P47041", "YJL058C" ] }, "reaction_10772766": { "compartment": "compartment_876", "id": "reaction_10772766", "reactome": "R-SCE-1299318", "name": "Activation of TASK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772763", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10766256": { "compartment": "compartment_70101", "id": "reaction_10766256", "reactome": "R-SCE-174124", "name": "Dephosphorylation of phospho-Cdh1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766246", "species_29356" ], "products": [ "species_10766234", "species_111294" ], "modifiers": [ [ "species_10766253", "catalyst" ] ], "additional_components": [ "YGL003C", "YGL003C", "Q00684", "YFR028C" ] }, "reaction_10769735": { "compartment": "compartment_7660", "id": "reaction_10769735", "reactome": "R-SCE-427514", "name": "eNoSC deacetylates histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769718", "species_427523" ], "products": [ "species_10768101", "species_427498", "species_427497" ], "modifiers": [ [ "species_10769732", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P06700", "YDL042C", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P38961", "YDR083W", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10769738": { "compartment": "compartment_7660", "id": "reaction_10769738", "reactome": "R-SCE-427527", "name": "eNoSC dimethylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768101", "species_77087" ], "products": [ "species_77502", "species_10763784" ], "modifiers": [ [ "species_10769732", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P06700", "YDL042C", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P38961", "YDR083W", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10765828": { "compartment": "compartment_5460", "id": "reaction_10765828", "reactome": "R-SCE-164840", "name": "ADP and Pi bind to ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_10765816" ], "products": [ "species_10765818" ], "modifiers": [], "additional_components": [ "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P30902", "YKL016C", "species_29370", "P21306", "YPL271W", "P38077", "YBR039W", "P07251", "ATP1", "P00854", "Q0085", "species_29372", "P00830", "ATP2", "P61829", "OLI1", "P05626", "YPL078C", "Q12165", "YDL004W", "P09457", "YDR298C", "Q12233", "YPR020W" ] }, "reaction_10765823": { "compartment": "compartment_5460", "id": "reaction_10765823", "reactome": "R-SCE-164832", "name": "ATPase synthesizes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765818" ], "products": [ "species_113521", "species_10765820" ], "modifiers": [ [ "species_10765818", "catalyst" ] ], "additional_components": [ "P24814", "YJR090C", "P30902", "YKL016C", "species_29370", "P21306", "YPL271W", "P38077", "YBR039W", "P07251", "ATP1", "P00854", "Q0085", "species_29372", "P00830", "ATP2", "P61829", "OLI1", "P05626", "YPL078C", "Q12165", "YDL004W", "P09457", "YDR298C", "Q12233", "YPR020W", "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "species_113592", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P30902", "YKL016C", "species_29370", "P21306", "YPL271W", "P38077", "YBR039W", "P07251", "ATP1", "P00854", "Q0085", "species_29372", "P00830", "ATP2", "P61829", "OLI1", "P05626", "YPL078C", "Q12165", "YDL004W", "P09457", "YDR298C", "Q12233", "YPR020W" ] }, "reaction_10765826": { "compartment": "compartment_5460", "id": "reaction_10765826", "reactome": "R-SCE-164834", "name": "Enzyme-bound ATP is released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163953", "species_10765820" ], "products": [ "species_113529", "species_113593", "species_10765816" ], "modifiers": [ [ "species_10765820", "catalyst" ] ], "additional_components": [ "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "species_113592", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "species_113592", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W" ] }, "reaction_10783791": { "compartment": "compartment_70101", "id": "reaction_10783791", "reactome": "R-SCE-6799545", "name": "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6799540", "species_29356" ], "products": [ "species_429579", "species_6799543" ], "modifiers": [ [ "species_10783788", "catalyst" ] ], "additional_components": [ "species_158417", "P22855", "YGL156W" ] }, "reaction_10765881": { "compartment": "compartment_70101", "id": "reaction_10765881", "reactome": "R-SCE-165766", "name": "Phosphorylation and activation of eIF4G by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762672", "species_113592" ], "products": [ "species_29370", "species_10765879" ], "modifiers": [ [ "species_10765848", "catalyst" ] ], "additional_components": [ "P39936", "YGL049C", "P39935", "YGR162W", "P39936", "YGL049C", "P39935", "YGR162W", "YBR028C" ] }, "reaction_10765867": { "compartment": "compartment_70101", "id": "reaction_10765867", "reactome": "R-SCE-165726", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10762517" ], "products": [ "species_29370", "species_10765864" ], "modifiers": [ [ "species_10765848", "catalyst" ] ], "additional_components": [ "P0CX37", "RPS6A", "P0CX38", "RPS6B", "P0CX37", "RPS6A", "P0CX38", "RPS6B", "YBR028C" ] }, "reaction_10789075": { "compartment": "compartment_70101", "id": "reaction_10789075", "reactome": "R-SCE-9679044", "name": "FKBP1A binds sirolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678687", "species_10789071" ], "products": [ "species_10789073" ], "modifiers": [], "additional_components": [ "YNL135C", "species_9678687", "P20081", "YNL135C" ] }, "reaction_10770295": { "compartment": "compartment_876", "id": "reaction_10770295", "reactome": "R-SCE-445714", "name": "Aquaporin-3 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10770292", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10789035": { "compartment": "compartment_70101", "id": "reaction_10789035", "reactome": "R-SCE-9668389", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789031", "species_10771525" ], "products": [ "species_10789033" ], "modifiers": [], "additional_components": [ "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "P39955", "YER047C", "Q04272", "YMR077C", "P53843", "YNL265C", "YPR173C", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P52917", "YPR173C", "P36108", "YKL002W", "P39955", "YER047C", "Q04272", "YMR077C", "P53843", "YNL265C" ] }, "reaction_10789037": { "compartment": "compartment_70101", "id": "reaction_10789037", "reactome": "R-SCE-9668405", "name": "SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789019", "species_10789029" ], "products": [ "species_10789031" ], "modifiers": [], "additional_components": [ "YER047C", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "Q04272", "YMR077C", "P53843", "YNL265C", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "P39955", "YER047C", "Q04272", "YMR077C", "P53843", "YNL265C" ] }, "reaction_10789040": { "compartment": "compartment_70101", "id": "reaction_10789040", "reactome": "R-SCE-9668419", "name": "SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768744", "species_113592", "species_29356" ], "products": [ "species_29370", "species_10768740", "species_29372" ], "modifiers": [ [ "species_10789031", "catalyst" ] ], "additional_components": [ "species_29420", "P09734", "YML124C", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "species_29420", "P09734", "YML124C", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "P39955", "YER047C", "Q04272", "YMR077C", "P53843", "YNL265C" ] }, "reaction_10786014": { "compartment": "compartment_876", "id": "reaction_10786014", "reactome": "R-SCE-8855130", "name": "VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786004" ], "products": [ "species_10786012" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "P09232", "YEL060C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P09232", "YEL060C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C" ] }, "reaction_10781954": { "compartment": "compartment_1660541", "id": "reaction_10781954", "reactome": "R-SCE-6784738", "name": "Degradation of PCSK9:LDLR:Clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781950" ], "products": [ "species_10781948" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "P09232", "YEL060C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C" ] }, "reaction_10785158": { "compartment": "compartment_70101", "id": "reaction_10785158", "reactome": "R-SCE-6813720", "name": "NCEH1 hydrolyzes cholesterol esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163579", "species_29356" ], "products": [ "species_216762", "species_8876730" ], "modifiers": [ [ "species_10785155", "catalyst" ] ], "additional_components": [ "YGR263C" ] }, "reaction_10768163": { "compartment": "compartment_984", "id": "reaction_10768163", "reactome": "R-SCE-264695", "name": "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194276", "species_171149" ], "products": [ "species_194236", "species_171076" ], "modifiers": [ [ "species_10768160", "catalyst" ] ], "additional_components": [ "P47139", "YJR098C", "P54857", "YDR058C" ] }, "reaction_10786892": { "compartment": "compartment_12045", "id": "reaction_10786892", "reactome": "R-SCE-8876485", "name": "CHOL translocates from lysosome membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786890" ], "products": [ "species_193384", "species_10786888" ], "modifiers": [], "additional_components": [ "Q12200", "YPL006W", "species_171095", "YPL006W" ] }, "reaction_10781952": { "compartment": "compartment_1660541", "id": "reaction_10781952", "reactome": "R-SCE-6784729", "name": "PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781918" ], "products": [ "species_10781950" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P09232", "YEL060C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P36000", "YKL135C", "P09232", "YEL060C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C" ] }, "reaction_10785516": { "compartment": "compartment_70101", "id": "reaction_10785516", "reactome": "R-SCE-8850945", "name": "Casein kinase II phosphorylates PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767316", "species_113592" ], "products": [ "species_29370", "species_10785514" ], "modifiers": [ [ "species_10774577", "catalyst" ] ], "additional_components": [ "YNL128W", "YNL128W", "P15790", "CKA1", "P38930", "CKB2", "P19454", "CKA2" ] }, "reaction_10787467": { "compartment": "compartment_70101", "id": "reaction_10787467", "reactome": "R-SCE-8948800", "name": "TNKS and TNKS2 PARylate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767316", "species_29360" ], "products": [ "species_10787457", "species_197277" ], "modifiers": [ [ "species_10787462", "catalyst" ] ], "additional_components": [ "YNL128W", "YNL128W", "YGR232W" ] }, "reaction_10784359": { "compartment": "compartment_70101", "id": "reaction_10784359", "reactome": "R-SCE-6807206", "name": "USP13 and OTUD3 deubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784356", "species_29356" ], "products": [ "species_10767316", "species_10760634" ], "modifiers": [ [ "species_10781697", "catalyst" ] ], "additional_components": [ "YNL128W", "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YBR058C" ] }, "reaction_10784353": { "compartment": "compartment_70101", "id": "reaction_10784353", "reactome": "R-SCE-6807134", "name": "NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767316", "species_10760634" ], "products": [ "species_10784348" ], "modifiers": [ [ "species_10772117", "catalyst" ] ], "additional_components": [ "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YNL128W", "YER125W" ] }, "reaction_10785528": { "compartment": "compartment_70101", "id": "reaction_10785528", "reactome": "R-SCE-8850992", "name": "Proteasome degrades polyubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785526" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P53916", "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10784088": { "compartment": "compartment_876", "id": "reaction_10784088", "reactome": "R-SCE-6801101", "name": "RABGGTA binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784079", "species_10784084" ], "products": [ "species_10784086" ], "modifiers": [], "additional_components": [ "YJL031C", "YPR176C", "P20133", "YPR176C", "Q00618", "YJL031C" ] }, "reaction_10784074": { "compartment": "compartment_70101", "id": "reaction_10784074", "reactome": "R-SCE-6800793", "name": "PIDD1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784068" ], "products": [ "species_10784072" ], "modifiers": [], "additional_components": [ "YJL005W", "YJL005W" ] }, "reaction_10784097": { "compartment": "compartment_70101", "id": "reaction_10784097", "reactome": "R-SCE-6801109", "name": "CHM binds RGGT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784093", "species_10784086" ], "products": [ "species_10784095" ], "modifiers": [], "additional_components": [ "YOR370C", "P20133", "YPR176C", "Q00618", "YJL031C", "P32864", "YOR370C", "P20133", "YPR176C", "Q00618", "YJL031C" ] }, "reaction_10784124": { "compartment": "compartment_17927", "id": "reaction_10784124", "reactome": "R-SCE-6801242", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784120", "species_10784101" ], "products": [ "species_10784122" ], "modifiers": [], "additional_components": [ "P35200", "YLR168C", "Q05776", "YLR193C", "Q04006", "YDR185C", "P35200", "YLR168C", "Q05776", "YLR193C", "Q04006", "YDR185C", "O60200", "MDM35" ] }, "reaction_10784070": { "compartment": "compartment_7660", "id": "reaction_10784070", "reactome": "R-SCE-6800490", "name": "ATM phosphorylates PIDD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10784065" ], "products": [ "species_113582", "species_10784068" ], "modifiers": [ [ "species_10768327", "catalyst" ] ], "additional_components": [ "YJL005W", "YJL005W", "YBL088C" ] }, "reaction_10784127": { "compartment": "compartment_17906", "id": "reaction_10784127", "reactome": "R-SCE-6801250", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590" ], "products": [ "species_1524101" ], "modifiers": [ [ "species_10784122", "catalyst" ] ], "additional_components": [ "P35200", "YLR168C", "Q05776", "YLR193C", "Q04006", "YDR185C", "O60200", "MDM35" ] }, "reaction_10788980": { "compartment": "compartment_70101", "id": "reaction_10788980", "reactome": "R-SCE-9661405", "name": "ABCC1 transports BIL from cytosol to extracellular region (blood)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189386" ], "products": [ "species_9661418" ], "modifiers": [ [ "species_10768249", "catalyst" ] ], "additional_components": [ "YDR135C" ] }, "reaction_10779396": { "compartment": "compartment_7660", "id": "reaction_10779396", "reactome": "R-SCE-5683792", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779391" ], "products": [ "species_113582", "species_10761098" ], "modifiers": [ [ "species_10779391", "catalyst" ] ], "additional_components": [ "P39009", "YDL101C", "YDL101C", "P39009", "YDL101C" ] }, "reaction_10766387": { "compartment": "compartment_7660", "id": "reaction_10766387", "reactome": "R-SCE-176264", "name": "Recruitment of the Rad9-Hus1-Rad1 complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766382", "species_10766378" ], "products": [ "species_10766384" ], "modifiers": [ [ "species_10766382", "catalyst" ] ], "additional_components": [ "P22336", "YAR007C", "P32641", "YER173W", "P40348", "YJR068W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "Q02574", "YLR288C", "Q08949", "YPL194W", "P48581", "YOR368W", "Q02574", "YLR288C", "P22336", "YAR007C", "Q08949", "YPL194W", "P32641", "YER173W", "P40348", "YJR068W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P48581", "YOR368W", "P38629", "YNL290W", "P22336", "YAR007C", "P32641", "YER173W", "P40348", "YJR068W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W" ] }, "reaction_10787270": { "compartment": "compartment_70101", "id": "reaction_10787270", "reactome": "R-SCE-8941895", "name": "Formation of CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787266", "species_10787216" ], "products": [ "species_10787268" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P00546", "YBR160W", "P36005", "YKL161C", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10760833": { "compartment": "compartment_7660", "id": "reaction_10760833", "reactome": "R-SCE-68950", "name": "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10760281", "species_30187", "species_29604", "species_29892" ], "products": [ "species_10760830" ], "modifiers": [ [ "species_10760246", "catalyst" ] ], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W" ] }, "reaction_10785898": { "compartment": "compartment_70101", "id": "reaction_10785898", "reactome": "R-SCE-8853496", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785889", "species_10785894" ], "products": [ "species_10785896" ], "modifiers": [], "additional_components": [ "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "YPL209C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C" ] }, "reaction_10763956": { "compartment": "compartment_7660", "id": "reaction_10763956", "reactome": "R-SCE-75809", "name": "Phosphorylation of Cdc25C at Ser216 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763791", "species_29358" ], "products": [ "species_10763794", "species_113582" ], "modifiers": [ [ "species_10761098", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "YDL101C" ] }, "reaction_10774551": { "compartment": "compartment_70101", "id": "reaction_10774551", "reactome": "R-SCE-2529015", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774539", "species_29356" ], "products": [ "species_10774549", "species_29372" ], "modifiers": [ [ "species_2529006", "catalyst" ] ], "additional_components": [ "P38170", "YBL097W", "P38989", "YFR031C", "Q12267", "YLR086W", "Q06156", "YLR272C", "Q06680", "YDR325W", "P38170", "YBL097W", "P38989", "YFR031C", "Q12267", "YLR086W", "Q06156", "YLR272C", "Q06680", "YDR325W" ] }, "reaction_10784202": { "compartment": "compartment_7660", "id": "reaction_10784202", "reactome": "R-SCE-6804724", "name": "MDM2 ubiquitinates phosphorylated MDM4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768310", "species_10760537" ], "products": [ "species_10784199" ], "modifiers": [ [ "species_10768310", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W" ] }, "reaction_10774378": { "compartment": "compartment_1598585", "id": "reaction_10774378", "reactome": "R-SCE-2466068", "name": "Phosphorylation of cohesin by PLK1 at chromosomal arms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10774363" ], "products": [ "species_10774375", "species_29370" ], "modifiers": [ [ "species_10768675", "catalyst" ] ], "additional_components": [ "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "YMR001C" ] }, "reaction_10788671": { "compartment": "compartment_13231", "id": "reaction_10788671", "reactome": "R-SCE-9624798", "name": "LBR binds KPNB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788667", "species_10768074" ], "products": [ "species_10788669" ], "modifiers": [], "additional_components": [ "YNL280C", "YLR347C", "Q06142", "YLR347C", "P32462", "YNL280C" ] }, "reaction_10763796": { "compartment": "compartment_7660", "id": "reaction_10763796", "reactome": "R-SCE-75010", "name": "Phosphorylation of Cdc25C at Ser 216 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763791", "species_29358" ], "products": [ "species_10763794", "species_113582" ], "modifiers": [ [ "species_10761086", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "P36002", "YKL198C", "P47116", "YJR059W", "P06782", "YDR477W" ] }, "reaction_10774466": { "compartment": "compartment_7660", "id": "reaction_10774466", "reactome": "R-SCE-2473152", "name": "Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10774462" ], "products": [ "species_2485002", "species_10774464" ], "modifiers": [ [ "species_10774449", "catalyst" ] ], "additional_components": [ "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "YFR027W" ] }, "reaction_10766462": { "compartment": "compartment_7660", "id": "reaction_10766462", "reactome": "R-SCE-187948", "name": "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10766260" ], "products": [ "species_113582", "species_10766262" ], "modifiers": [ [ "species_10760454", "catalyst" ] ], "additional_components": [ "YGL003C", "YGL003C", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10787375": { "compartment": "compartment_7660", "id": "reaction_10787375", "reactome": "R-SCE-8942836", "name": "CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10787337" ], "products": [ "species_113582", "species_10787373" ], "modifiers": [ [ "species_10763257", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "Q03290", "YDR460W", "P37366", "YPR025C", "P06242", "YDL108W" ] }, "reaction_10788685": { "compartment": "compartment_70101", "id": "reaction_10788685", "reactome": "R-SCE-9624876", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788673", "species_9624879" ], "products": [ "species_10788683" ], "modifiers": [], "additional_components": [ "P32835", "YLR293C", "species_29438", "P32835", "YLR293C", "species_29438" ] }, "reaction_10764018": { "compartment": "compartment_13231", "id": "reaction_10764018", "reactome": "R-SCE-75823", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763979" ], "products": [ "species_10764006" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10766207": { "compartment": "compartment_13231", "id": "reaction_10766207", "reactome": "R-SCE-170159", "name": "Translocation of Cdc25 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766203" ], "products": [ "species_10766205" ], "modifiers": [], "additional_components": [ "P23748", "YMR036C", "P23748", "YMR036C" ] }, "reaction_10788374": { "compartment": "compartment_70101", "id": "reaction_10788374", "reactome": "R-SCE-9029987", "name": "p-S216-CDC25C translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763794" ], "products": [ "species_10763798" ], "modifiers": [], "additional_components": [ "YMR036C", "YMR036C" ] }, "reaction_10760284": { "compartment": "compartment_7660", "id": "reaction_10760284", "reactome": "R-SCE-68913", "name": "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10760279" ], "products": [ "species_10760281", "species_10760275" ], "modifiers": [ [ "species_10760279", "catalyst" ] ], "additional_components": [ "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P20457", "YKL045W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P20457", "YKL045W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P38121", "YBL035C", "P13382", "YNL102W", "P10363", "YIR008C", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "P20457", "YKL045W" ] }, "reaction_10774945": { "compartment": "compartment_70101", "id": "reaction_10774945", "reactome": "R-SCE-3002798", "name": "Cytosolic PLK1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765349" ], "products": [ "species_10765474" ], "modifiers": [], "additional_components": [ "YMR001C", "YMR001C" ] }, "reaction_10766199": { "compartment": "compartment_13231", "id": "reaction_10766199", "reactome": "R-SCE-170149", "name": "Translocation of active Cdc25C to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765343" ], "products": [ "species_10766197" ], "modifiers": [], "additional_components": [ "YMR036C", "YMR036C" ] }, "reaction_10789351": { "compartment": "compartment_7660", "id": "reaction_10789351", "reactome": "R-SCE-9754129", "name": "CDK6 inhibitors bind CDK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9754132", "species_10787355" ], "products": [ "species_10789349" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=10426", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=7379", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "P24868", "YGR108W", "P00546", "YBR160W", "P36005", "YKL161C", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10426", "P20438", "YPL256C", "P32943", "YGR109C", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "LigandDisplayForward?ligandId=7934" ] }, "reaction_10788688": { "compartment": "compartment_70101", "id": "reaction_10788688", "reactome": "R-SCE-9624893", "name": "RAN stimulates fusion of nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788683", "species_29356" ], "products": [ "species_10767791", "species_29372", "species_9624890" ], "modifiers": [ [ "species_10774940", "catalyst" ] ], "additional_components": [ "P32835", "YLR293C", "species_29438", "species_29420", "P32835", "YLR293C", "P11745", "YMR235C", "Q12306", "YDR510W" ] }, "reaction_10789361": { "compartment": "compartment_7660", "id": "reaction_10789361", "reactome": "R-SCE-9754130", "name": "CDK4 inhibitors bind CDK4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787371", "species_9754127" ], "products": [ "species_10789359" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "LigandDisplayForward?ligandId=7938", "LigandDisplayForward?ligandId=5950", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=10426", "LigandDisplayForward?ligandId=5707", "LigandDisplayForward?ligandId=7744", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "pubchem.compound:9933545", "LigandDisplayForward?ligandId=8203", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=5680", "LigandDisplayForward?ligandId=7938", "P13365", "YAL040C", "LigandDisplayForward?ligandId=11189", "P24868", "YGR108W", "P00546", "YBR160W", "P36005", "YKL161C", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5707", "LigandDisplayForward?ligandId=7383", "P24869", "YPR119W", "pubchem.compound:9933545", "LigandDisplayForward?ligandId=8203", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=5950", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=10426", "P20438", "YPL256C", "P32943", "YGR109C", "LigandDisplayForward?ligandId=7744", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7382", "P30283", "YPR120C", "P20437", "YMR199W", "LigandDisplayForward?ligandId=5680" ] }, "reaction_10774454": { "compartment": "compartment_7660", "id": "reaction_10774454", "reactome": "R-SCE-2468039", "name": "Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774436", "species_113560" ], "products": [ "species_2485002", "species_10774444" ], "modifiers": [ [ "species_10774449", "catalyst" ] ], "additional_components": [ "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "P32908", "YFL008W", "Q04264", "YMR076C", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "YFR027W" ] }, "reaction_10774580": { "compartment": "compartment_70101", "id": "reaction_10774580", "reactome": "R-SCE-2529020", "name": "CK2 phosphorylates condensin I subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774549", "species_113592" ], "products": [ "species_29370", "species_10774539" ], "modifiers": [ [ "species_10774577", "catalyst" ] ], "additional_components": [ "P38170", "YBL097W", "P38989", "YFR031C", "Q12267", "YLR086W", "Q06156", "YLR272C", "Q06680", "YDR325W", "P38170", "YBL097W", "P38989", "YFR031C", "Q12267", "YLR086W", "Q06156", "YLR272C", "Q06680", "YDR325W", "P15790", "CKA1", "P38930", "CKB2", "P19454", "CKA2" ] }, "reaction_10766243": { "compartment": "compartment_7660", "id": "reaction_10766243", "reactome": "R-SCE-174110", "name": "Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10766239" ], "products": [ "species_10766241", "species_113550" ], "modifiers": [ [ "species_10761051", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "YMR036C" ] }, "reaction_10774394": { "compartment": "compartment_70101", "id": "reaction_10774394", "reactome": "R-SCE-2467775", "name": "Autocleavage of ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774383" ], "products": [ "species_10774391" ], "modifiers": [ [ "species_10774383", "catalyst" ] ], "additional_components": [ "YGR098C", "Q03018", "YGR098C", "YGR098C" ] }, "reaction_10765338": { "compartment": "compartment_70101", "id": "reaction_10765338", "reactome": "R-SCE-141437", "name": "Formation of the MCC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765330", "species_10765320", "species_10765315", "species_10765325" ], "products": [ "species_10765332" ], "modifiers": [], "additional_components": [ "YJL030W", "YOR026W", "P47074", "YJL013C", "P41695", "YGR188C", "YGL116W", "P47074", "YJL013C", "P40958", "YJL030W", "P41695", "YGR188C", "P26309", "YGL116W", "P26449", "YOR026W" ] }, "reaction_10765336": { "compartment": "compartment_70101", "id": "reaction_10765336", "reactome": "R-SCE-141429", "name": "Inactivation of APC/C via CDC20 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765330", "species_10765325" ], "products": [ "species_10765334" ], "modifiers": [], "additional_components": [ "YJL030W", "YGL116W", "P40958", "YJL030W", "P26309", "YGL116W" ] }, "reaction_10774266": { "compartment": "compartment_20699", "id": "reaction_10774266", "reactome": "R-SCE-2214351", "name": "PLK1 phosphorylates GORASP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774258", "species_113592" ], "products": [ "species_10774263", "species_29370" ], "modifiers": [ [ "species_10774258", "catalyst" ] ], "additional_components": [ "P01123", "YFL038C", "P32562", "YMR001C", "species_29438", "Q04410", "YDR517W", "P01123", "YFL038C", "P32562", "YMR001C", "species_29438", "Q04410", "YDR517W", "P01123", "YFL038C", "P32562", "YMR001C", "species_29438", "Q04410", "YDR517W" ] }, "reaction_10784232": { "compartment": "compartment_7660", "id": "reaction_10784232", "reactome": "R-SCE-6804955", "name": "ATM phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10768288" ], "products": [ "species_113582", "species_10784230" ], "modifiers": [ [ "species_10768327", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "YBL088C" ] }, "reaction_10766264": { "compartment": "compartment_13231", "id": "reaction_10766264", "reactome": "R-SCE-174273", "name": "Translocation of Cyclin A:Cdk2 complexes to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766227" ], "products": [ "species_10766241" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10768330": { "compartment": "compartment_7660", "id": "reaction_10768330", "reactome": "R-SCE-349455", "name": "Phosphorylation of MDM4 by ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10768320" ], "products": [ "species_113582", "species_10768298" ], "modifiers": [ [ "species_10768327", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "YBL088C" ] }, "reaction_10777308": { "compartment": "compartment_13231", "id": "reaction_10777308", "reactome": "R-SCE-5221130", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_5221122" ], "products": [ "species_113550", "species_5221124" ], "modifiers": [ [ "species_10776501", "catalyst" ] ], "additional_components": [ "YMR165C" ] }, "reaction_10768312": { "compartment": "compartment_7660", "id": "reaction_10768312", "reactome": "R-SCE-349426", "name": "Phosphorylation of MDM4 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10768298" ], "products": [ "species_113582", "species_10768310" ], "modifiers": [ [ "species_10761098", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "YDL101C" ] }, "reaction_10764016": { "compartment": "compartment_13231", "id": "reaction_10764016", "reactome": "R-SCE-75822", "name": "Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763990" ], "products": [ "species_10764014" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10766229": { "compartment": "compartment_70101", "id": "reaction_10766229", "reactome": "R-SCE-174054", "name": "Formation of Cyclin A:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760999", "species_10766189" ], "products": [ "species_10766227" ], "modifiers": [], "additional_components": [ "YBR160W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10774943": { "compartment": "compartment_13231", "id": "reaction_10774943", "reactome": "R-SCE-3000449", "name": "UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774930", "species_10774813" ], "products": [ "species_10774805", "species_10774940" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P11745", "YMR235C", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "P11745", "YMR235C", "Q12306", "YDR510W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10787339": { "compartment": "compartment_13231", "id": "reaction_10787339", "reactome": "R-SCE-8942803", "name": "Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787303" ], "products": [ "species_10787337" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10788681": { "compartment": "compartment_1598585", "id": "reaction_10788681", "reactome": "R-SCE-9624845", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10767791" ], "products": [ "species_10788673", "species_29420" ], "modifiers": [ [ "species_10788678", "catalyst" ] ], "additional_components": [ "species_29420", "P32835", "YLR293C", "P32835", "YLR293C", "species_29438", "YGL097W" ] }, "reaction_10766195": { "compartment": "compartment_13231", "id": "reaction_10766195", "reactome": "R-SCE-170120", "name": "Translocation of Cdc25B to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766191" ], "products": [ "species_10766193" ], "modifiers": [], "additional_components": [ "YMR036C", "YMR036C" ] }, "reaction_10766465": { "compartment": "compartment_7660", "id": "reaction_10766465", "reactome": "R-SCE-187949", "name": "CAK-mediated phosphorylation of Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766241", "species_29358" ], "products": [ "species_113582", "species_10760454" ], "modifiers": [ [ "species_10763257", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03290", "YDR460W", "P37366", "YPR025C", "P06242", "YDL108W" ] }, "reaction_10779393": { "compartment": "compartment_7660", "id": "reaction_10779393", "reactome": "R-SCE-5683774", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779389" ], "products": [ "species_10779391" ], "modifiers": [], "additional_components": [ "YDL101C", "P39009", "YDL101C" ] }, "reaction_10784210": { "compartment": "compartment_7660", "id": "reaction_10784210", "reactome": "R-SCE-6804741", "name": "MDM2 forms homo- or heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768288", "species_10784204" ], "products": [ "species_10784208" ], "modifiers": [ [ "species_10768327", "inhibitor" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "YBL088C" ] }, "reaction_10785940": { "compartment": "compartment_70101", "id": "reaction_10785940", "reactome": "R-SCE-8854041", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760634", "species_10785896" ], "products": [ "species_10785937" ], "modifiers": [ [ "species_10785896", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C" ] }, "reaction_10764022": { "compartment": "compartment_70101", "id": "reaction_10764022", "reactome": "R-SCE-75825", "name": "Proteasome mediated degradation of Cyclin D1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764020" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P05759", "RPS31", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P30283", "YPR120C", "P20437", "YMR199W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10785942": { "compartment": "compartment_70101", "id": "reaction_10785942", "reactome": "R-SCE-8854044", "name": "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785937" ], "products": [ "species_10785889", "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P38991", "YPL209C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10772729": { "compartment": "compartment_876", "id": "reaction_10772729", "reactome": "R-SCE-1296348", "name": "Activation of TWIK-related K+ channel (TREK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772726", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10766923": { "compartment": "compartment_70101", "id": "reaction_10766923", "reactome": "R-SCE-195664", "name": "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_29368", "species_195691" ], "products": [ "species_29366", "species_195655", "species_29356" ], "modifiers": [ [ "species_10766920", "catalyst" ] ], "additional_components": [ "YLR056W" ] }, "reaction_10764912": { "compartment": "compartment_12045", "id": "reaction_10764912", "reactome": "R-SCE-111883", "name": "Hydrolysis of phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_140356", "species_428981" ], "modifiers": [ [ "species_10764907", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C", "species_429802" ] }, "reaction_10764967": { "compartment": "compartment_70101", "id": "reaction_10764967", "reactome": "R-SCE-112037", "name": "Inactivation of PLC beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764872", "species_29356" ], "products": [ "species_29372", "species_10764856", "species_10764965" ], "modifiers": [], "additional_components": [ "P32383", "YPL268W", "species_29438", "P10823", "YER020W", "YPL268W", "species_29420", "P10823", "YER020W" ] }, "reaction_10764909": { "compartment": "compartment_70101", "id": "reaction_10764909", "reactome": "R-SCE-111881", "name": "Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_74016", "species_10764905" ], "products": [ "species_10764907" ], "modifiers": [], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C", "species_429802" ] }, "reaction_10764875": { "compartment": "compartment_70101", "id": "reaction_10764875", "reactome": "R-SCE-111879", "name": "PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10764872", "catalyst" ] ], "additional_components": [ "P32383", "YPL268W", "species_29438", "P10823", "YER020W" ] }, "reaction_10764925": { "compartment": "compartment_70101", "id": "reaction_10764925", "reactome": "R-SCE-111898", "name": "Phosphorylation of cPLA2 by ERK-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10764922" ], "products": [ "species_29370", "species_10764905" ], "modifiers": [ [ "species_10764614", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C", "YBL016W" ] }, "reaction_10779083": { "compartment": "compartment_70101", "id": "reaction_10779083", "reactome": "R-SCE-5679041", "name": "ABCC2 transports BMG,BDG from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_5679042", "species_29356" ], "products": [ "species_29370", "species_5679034", "species_29372" ], "modifiers": [ [ "species_10772886", "catalyst" ] ], "additional_components": [ "species_159160", "species_159149", "species_159160", "species_159149", "P14772", "YLL015W", "P39109", "YDR135C", "P32386", "YLL048C", "P38735", "YHL035C" ] }, "reaction_10774756": { "compartment": "compartment_7660", "id": "reaction_10774756", "reactome": "R-SCE-2990833", "name": "Conjugation of SUMO1 to UBA2:SAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10774743", "species_10774738" ], "products": [ "species_10774753", "species_164121", "species_113541" ], "modifiers": [ [ "species_10774738", "catalyst" ] ], "additional_components": [ "YDR510W", "P52488", "YDR390C", "Q06624", "YPR180W", "P52488", "YDR390C", "Q06624", "YPR180W", "Q12306", "YDR510W", "P52488", "YDR390C", "Q06624", "YPR180W" ] }, "reaction_10774681": { "compartment": "compartment_70101", "id": "reaction_10774681", "reactome": "R-SCE-2730835", "name": "Autophosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767671", "species_113592" ], "products": [ "species_29370", "species_10774679" ], "modifiers": [], "additional_components": [ "species_112275", "P24583", "YBL105C", "species_112275", "P24583", "YBL105C" ] }, "reaction_10766028": { "compartment": "compartment_70101", "id": "reaction_10766028", "reactome": "R-SCE-168162", "name": "Phosphorylation of human JNKs by activated MKK4/MKK7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10765968" ], "products": [ "species_29370", "species_10765974" ], "modifiers": [ [ "species_10766025", "catalyst" ] ], "additional_components": [ "YPR054W", "YPR054W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10770904": { "compartment": "compartment_70101", "id": "reaction_10770904", "reactome": "R-SCE-451418", "name": "Pellino ubiquitinates IRAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770887" ], "products": [ "species_10770901" ], "modifiers": [ [ "species_10770887", "catalyst" ] ], "additional_components": [ "P43633", "YGL021W", "P32789", "YBL009W", "P05759", "RPS31", "P53152", "MMS2", "P52490", "UBC13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P43633", "YGL021W", "P32789", "YBL009W", "P53152", "MMS2", "P52490", "UBC13", "P43633", "YGL021W", "P32789", "YBL009W", "P05759", "RPS31", "P53152", "MMS2", "P52490", "UBC13", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10789090": { "compartment": "compartment_70101", "id": "reaction_10789090", "reactome": "R-SCE-9690461", "name": "FKBP1A binds tacrolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678991", "species_10789071" ], "products": [ "species_10789088" ], "modifiers": [], "additional_components": [ "YNL135C", "P20081", "YNL135C", "species_9678991" ] }, "reaction_10769144": { "compartment": "compartment_70101", "id": "reaction_10769144", "reactome": "R-SCE-392530", "name": "p-S400-Cot phosphorylates NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769138", "species_113592" ], "products": [ "species_29370", "species_10769141" ], "modifiers": [ [ "species_10768963", "catalyst" ] ], "additional_components": [ "YCR073C", "YCR073C", "P25390", "YCR073C", "P53599", "YNR031C" ] }, "reaction_10767769": { "compartment": "compartment_7660", "id": "reaction_10767769", "reactome": "R-SCE-203797", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10767354" ], "products": [ "species_10767374", "species_113550" ], "modifiers": [ [ "species_10767766", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "P41808", "YPR054W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P41808", "YPR054W", "Q00772", "YHR030C", "P14681", "YGR040W", "P40479", "YIL113W", "P38590", "YNL053W" ] }, "reaction_10772408": { "compartment": "compartment_70101", "id": "reaction_10772408", "reactome": "R-SCE-983156", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772358", "species_113592", "species_10772364" ], "products": [ "species_10772379", "species_111294", "species_10772356", "species_76577" ], "modifiers": [ [ "species_10772364", "catalyst" ] ], "additional_components": [ "P22515", "YKL210W", "P15732", "YDR059C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P05759", "RPS31", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52491", "YLR306W", "P21734", "YDR177W", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P32943", "YGR109C", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P22515", "YKL210W", "P15732", "YDR059C", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P52491", "YLR306W", "P21734", "YDR177W", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P32943", "YGR109C", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C" ] }, "reaction_10783476": { "compartment": "compartment_1462052", "id": "reaction_10783476", "reactome": "R-SCE-6798748", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783290" ], "products": [ "species_10783474" ], "modifiers": [], "additional_components": [ "Q06625", "YPR184W", "P32807", "YMR284W", "P25043", "YOR157C", "P06738", "YPR160W", "P02994", "YBR118W", "P47103", "YJR032W", "P04806", "YFR053C", "Q12096", "YOR320C", "Q04437", "YMR106C", "Q03262", "YMR278W", "P38764", "YHR027C", "P17121", "YDR389W", "Q04120", "YDR453C", "P52489", "YOR347C", "Q08723", "YOR261C", "P38930", "CKB2", "P12709", "YBR196C", "P36010", "YKL067W", "P34760", "YML028W", "P32485", "YLR113W", "P32379", "YGR253C", "P38696", "YHR129C", "P16862", "YMR205C", "P40361", "YJL070C", "P25694", "YDL126C", "P15202", "YDR256C", "P46958", "YJL146W", "P47011", "YJL137C", "Q06103", "YPR108W", "P21954", "YDL066W", "P16861", "YGR240C", "P17709", "YCL040W", "P23724", "YBL041W", "P50094", "YML056C", "P15274", "YML035C", "P33297", "YOR117W", "Q06204", "YLR446W", "Q03280", "YDR457W", "P38985", "YDL092W", "Q12377", "YDL097C", "P10592", "YLL024C", "P47079", "YJL008C", "P32873", "YPL115C", "P11633", "YBR089C-A", "P39960", "YER155C", "P32769", "YKR084C", "Q06549", "YLR245C", "P15891", "YCR088W", "Q12250", "YDL147W", "P04807", "YGL253W", "P00549", "YAL038W", "P50095", "YLR432W", "Q08491", "SKI7", "P23639", "YML092C", "Q12156", "YDR063W", "P39083", "YOR127W", "P53691", "YLR216C", "P32324", "EFT2", "P38697", "YHR216W", "P49435", "YML022W", "P02829", "YPL240C", "P38339", "YBR260C", "P39958", "YER136W", "P05373", "YGL040C", "Q05788", "YLR209C", "P06634", "YOR204W", "P38862", "YHR171W", "P40518", "YIL062C", "Q04409", "YDR516C", "P38150", "YJL070C", "Q06407", "YDR379W", "Q04062", "YDR427W", "P33299", "YKL145W", "P32464", "YKL189W", "P40016", "YER021W", "P15108", "YMR186W", "P39988", "YEL029C", "P43588", "YFR004W", "P36143", "YKR058W", "Q06625", "YPR184W", "P32807", "YMR284W", "P25043", "YOR157C", "P06738", "YPR160W", "P02994", "YBR118W", "P47103", "YJR032W", "P04806", "YFR053C", "Q12096", "YOR320C", "Q04437", "YMR106C", "Q03262", "YMR278W", "P38764", "YHR027C", "P17121", "YDR389W", "Q04120", "YDR453C", "P52489", "YOR347C", "Q08723", "YOR261C", "P38930", "CKB2", "P12709", "YBR196C", "P36010", "YKL067W", "P34760", "YML028W", "P32485", "YLR113W", "P32379", "YGR253C", "P38696", "YHR129C", "P16862", "YMR205C", "P40361", "YJL070C", "P25694", "YDL126C", "P15202", "YDR256C", "P46958", "YJL146W", "P47011", "YJL137C", "Q06103", "YPR108W", "P21954", "YDL066W", "P16861", "YGR240C", "P17709", "YCL040W", "P23724", "YBL041W", "P50094", "YML056C", "P15274", "YML035C", "P33297", "YOR117W", "Q06204", "YLR446W", "Q03280", "YDR457W", "P38985", "YDL092W", "Q12377", "YDL097C", "P10592", "YLL024C", "P47079", "YJL008C", "P32873", "YPL115C", "P11633", "YBR089C-A", "P39960", "YER155C", "P32769", "YKR084C", "Q06549", "YLR245C", "P15891", "YCR088W", "Q12250", "YDL147W", "P04807", "YGL253W", "P00549", "YAL038W", "P50095", "YLR432W", "Q08491", "SKI7", "P23639", "YML092C", "Q12156", "YDR063W", "P39083", "YOR127W", "P53691", "YLR216C", "P32324", "EFT2", "P38697", "YHR216W", "P49435", "YML022W", "P02829", "YPL240C", "P38339", "YBR260C", "P39958", "YER136W", "P05373", "YGL040C", "Q05788", "YLR209C", "P06634", "YOR204W", "P38862", "YHR171W", "P40518", "YIL062C", "Q04409", "YDR516C", "P38150", "YJL070C", "Q06407", "YDR379W", "Q04062", "YDR427W", "P33299", "YKL145W", "P32464", "YKL189W", "P40016", "YER021W", "P15108", "YMR186W", "P39988", "YEL029C", "P43588", "YFR004W", "P36143", "YKR058W" ] }, "reaction_10774052": { "compartment": "compartment_876", "id": "reaction_10774052", "reactome": "R-SCE-2029471", "name": "Hydrolysis of PC to PA by PLD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_29356" ], "products": [ "species_264618", "species_1602448" ], "modifiers": [ [ "species_10774047", "catalyst" ] ], "additional_components": [ "YKR031C" ] }, "reaction_10772367": { "compartment": "compartment_70101", "id": "reaction_10772367", "reactome": "R-SCE-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10772360" ], "products": [ "species_111294", "species_10772356", "species_10772364", "species_76577" ], "modifiers": [ [ "species_10772267", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "Q08273", "YOL133W", "P22515", "YKL210W", "P15732", "YDR059C", "P38042", "YBL084C", "P52490", "UBC13", "Q04601", "YDR118W", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P52492", "YOR339C", "P06104", "YGL058W", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P53197", "YGL003C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "P52286", "YDR328C", "P28263", "YEL012W", "P54860", "YDL190C", "P26309", "YGL116W", "P33296", "YER100W", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P53152", "MMS2", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P20437", "YMR199W", "P21734", "YDR177W", "P53886", "YNL172W", "P39940", "YER125W", "Q12018", "YDL132W", "P24868", "YGR108W", "Q02159", "YMR022W", "Q05164", "YOL155C", "P15731", "YBR082C", "P24869", "YPR119W", "P25382", "YCR072C", "P52491", "YLR306W", "P19812", "YGR184C", "Q08683", "YOR249C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P32943", "YGR109C", "P14682", "YDR054C", "P30283", "YPR120C", "P16522", "YHR166C", "Q12347", "YLR097C", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P22515", "YKL210W", "P15732", "YDR059C", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P52491", "YLR306W", "P21734", "YDR177W", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P32943", "YGR109C", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C" ] }, "reaction_10783866": { "compartment": "compartment_6800424", "id": "reaction_10783866", "reactome": "R-SCE-6800426", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783854" ], "products": [ "species_10783864" ], "modifiers": [], "additional_components": [ "P38142", "YBR241C", "P37296", "YMR054W", "P32563", "YOR270C", "P38065", "YBL037W", "Q02647", "YDR424C", "P06780", "YPR165W", "P25353", "YCR026C", "P25515", "YEL027W", "P41810", "YDR238C", "P38142", "YBR241C", "P37296", "YMR054W", "P32563", "YOR270C", "P38065", "YBL037W", "Q02647", "YDR424C", "P06780", "YPR165W", "P25353", "YCR026C", "P25515", "YEL027W", "P41810", "YDR238C" ] }, "reaction_10772633": { "compartment": "compartment_1222693", "id": "reaction_10772633", "reactome": "R-SCE-1222516", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10772630", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "P23968", "YHR026W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10769326": { "compartment": "compartment_70101", "id": "reaction_10769326", "reactome": "R-SCE-418436", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29468", "species_29368" ], "products": [ "species_29366", "species_202124", "species_29968" ], "modifiers": [ [ "species_10769321", "catalyst" ] ], "additional_components": [ "YHR042W" ] }, "reaction_10767230": { "compartment": "compartment_7660", "id": "reaction_10767230", "reactome": "R-SCE-198669", "name": "p38MAPK phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767221", "species_29358" ], "products": [ "species_113582", "species_10767227" ], "modifiers": [ [ "species_10765922", "catalyst" ] ], "additional_components": [ "YBR028C", "YBR028C", "YLR113W" ] }, "reaction_10787198": { "compartment": "compartment_70101", "id": "reaction_10787198", "reactome": "R-SCE-8940641", "name": "THOP1 cleaves oligopeptide fragment (8-16aa)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983032" ], "products": [ "species_8955634" ], "modifiers": [ [ "species_10787195", "catalyst" ] ], "additional_components": [ "YCL057W" ] }, "reaction_10772582": { "compartment": "compartment_70101", "id": "reaction_10772582", "reactome": "R-SCE-1168373", "name": "PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_10765242", "species_33625", "species_114519" ], "products": [ "species_10765252" ], "modifiers": [], "additional_components": [ "YBL105C", "species_33625", "P24583", "YBL105C", "species_74016", "species_6797635" ] }, "reaction_10775012": { "compartment": "compartment_70101", "id": "reaction_10775012", "reactome": "R-SCE-3204303", "name": "MRE11 binds cytosolic DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_874088", "species_10775008" ], "products": [ "species_10775010" ], "modifiers": [], "additional_components": [ "P32829", "MRE11", "species_874088" ] }, "reaction_10783010": { "compartment": "compartment_6800173", "id": "reaction_10783010", "reactome": "R-SCE-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782978" ], "products": [ "species_10783008" ], "modifiers": [], "additional_components": [ "P49954", "YLR351C", "P36110", "YKR013W", "Q06549", "YLR245C", "P47033", "YJL078C", "P41912", "YOL110W", "P15891", "YCR088W", "P21954", "YDL066W", "Q10740", "YNL045W", "P43599", "YFR018C", "P07267", "YPL154C", "P40547", "YIL017C", "P33401", "YKL127W", "P47032", "YJL079C", "P49954", "YLR351C", "P36110", "YKR013W", "Q06549", "YLR245C", "P47033", "YJL078C", "P41912", "YOL110W", "P15891", "YCR088W", "P21954", "YDL066W", "Q10740", "YNL045W", "P43599", "YFR018C", "P07267", "YPL154C", "P40547", "YIL017C", "P33401", "YKL127W", "P47032", "YJL079C" ] }, "reaction_10770716": { "compartment": "compartment_7660", "id": "reaction_10770716", "reactome": "R-SCE-450333", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10770713" ], "products": [ "species_113582", "species_10770632" ], "modifiers": [ [ "species_10770705", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10774045": { "compartment": "compartment_876", "id": "reaction_10774045", "reactome": "R-SCE-2029468", "name": "Conversion of PA into DAG by PAP-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_29356" ], "products": [ "species_29372", "species_112275" ], "modifiers": [ [ "species_10774042", "catalyst" ] ], "additional_components": [ "Q05521", "YDR284C", "Q04396", "YDR503C" ] }, "reaction_10783692": { "compartment": "compartment_1470028", "id": "reaction_10783692", "reactome": "R-SCE-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783636" ], "products": [ "species_10783690" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "P17555", "YNL138W", "P06738", "YPR160W", "P40358", "YJL073W", "P39076", "YIL142W", "P02557", "YFL037W", "P36022", "YKR054C", "P32565", "YIL075C", "P17121", "YDR389W", "Q03630", "YML077W", "P50095", "YLR432W", "P53094", "YGL197W", "Q03862", "YDR101C", "P32381", "YDL029W", "Q04228", "YML013W", "P25694", "YDL126C", "P00812", "YPL111W", "P38697", "YHR216W", "P39958", "YER136W", "Q12229", "YDL091C", "Q08412", "YOR042W", "P50094", "YML056C", "P38626", "YIL043C", "P32634", "YER132C", "P40557", "YIL005W", "P24583", "YBL105C", "P47079", "YJL008C", "Q02933", "YPL123C", "P34227", "YBL064C", "P40568", "YIR010W", "P53843", "YNL265C", "P16892", "YBL016W", "P17555", "YNL138W", "P06738", "YPR160W", "P40358", "YJL073W", "P39076", "YIL142W", "P02557", "YFL037W", "P36022", "YKR054C", "P32565", "YIL075C", "P17121", "YDR389W", "Q03630", "YML077W", "P50095", "YLR432W", "P53094", "YGL197W", "Q03862", "YDR101C", "P32381", "YDL029W", "Q04228", "YML013W", "P25694", "YDL126C", "P00812", "YPL111W", "P38697", "YHR216W", "P39958", "YER136W", "Q12229", "YDL091C", "Q08412", "YOR042W", "P50094", "YML056C", "P38626", "YIL043C", "P32634", "YER132C", "P40557", "YIL005W", "P24583", "YBL105C", "P47079", "YJL008C", "Q02933", "YPL123C", "P34227", "YBL064C", "P40568", "YIR010W", "P53843", "YNL265C" ] }, "reaction_10783061": { "compartment": "compartment_6799713", "id": "reaction_10783061", "reactome": "R-SCE-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783055" ], "products": [ "species_10783059" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "P32660", "YER166W", "P38142", "YBR241C", "P39524", "YAL026C", "Q12675", "YDR093W", "P33328", "YOR327C", "Q02647", "YDR424C", "Q04359", "YMR017W", "P36126", "YKR031C", "P25515", "YEL027W", "P31109", "YAL030W", "Q12674", "YMR162C", "P41810", "YDR238C", "P40357", "YGR009C", "P38142", "YBR241C", "P33328", "YOR327C", "Q04359", "YMR017W", "P25515", "YEL027W", "P31109", "YAL030W", "P41810", "YDR238C", "P32660", "YER166W", "P39524", "YAL026C", "Q12675", "YDR093W", "Q02647", "YDR424C", "P36126", "YKR031C", "Q12674", "YMR162C" ] }, "reaction_10766032": { "compartment": "compartment_7660", "id": "reaction_10766032", "reactome": "R-SCE-168440", "name": "Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765963", "species_10765915" ], "products": [ "species_10766030" ], "modifiers": [], "additional_components": [ "YEL009C", "P39970", "YER045C", "P40535", "YIL036W", "Q02100", "YNL167C", "P39970", "YER045C", "P40535", "YIL036W", "P03069", "YEL009C", "Q02100", "YNL167C" ] }, "reaction_10772715": { "compartment": "compartment_70101", "id": "reaction_10772715", "reactome": "R-SCE-1247960", "name": "Activation of p38 MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10772704" ], "products": [ "species_29370", "species_10772712" ], "modifiers": [ [ "species_10770681", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P32485", "YLR113W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10783523": { "compartment": "compartment_6799371", "id": "reaction_10783523", "reactome": "R-SCE-6798749", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783509" ], "products": [ "species_10783521" ], "modifiers": [], "additional_components": [ "P00812", "YPL111W", "P49954", "YLR351C", "P36110", "YKR013W", "P47033", "YJL078C", "Q06142", "YLR347C", "Q06409", "YLR422W", "P43599", "YFR018C", "P07267", "YPL154C", "P40547", "YIL017C", "P27796", "YIL160C", "Q08412", "YOR042W", "P39988", "YEL029C", "P47032", "YJL079C", "P00812", "YPL111W", "P49954", "YLR351C", "P36110", "YKR013W", "P47033", "YJL078C", "Q06142", "YLR347C", "Q06409", "YLR422W", "P43599", "YFR018C", "P07267", "YPL154C", "P40547", "YIL017C", "P27796", "YIL160C", "Q08412", "YOR042W", "P39988", "YEL029C", "P47032", "YJL079C" ] }, "reaction_10770641": { "compartment": "compartment_7660", "id": "reaction_10770641", "reactome": "R-SCE-450222", "name": "Active p38 MAPK phosphorylates MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10770632" ], "products": [ "species_113582", "species_10770638" ], "modifiers": [ [ "species_10770632", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W" ] }, "reaction_10783779": { "compartment": "compartment_6799351", "id": "reaction_10783779", "reactome": "R-SCE-6799350", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10783765" ], "products": [ "species_10783777" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "Q06144", "YLR350W", "P38142", "YBR241C", "P53142", "YGL104C", "P33328", "YOR327C", "P32901", "YKR093W", "Q00776", "YPL259C", "Q04359", "YMR017W", "P53224", "YGR038W", "P31109", "YAL030W", "P13856", "YGR152C", "P33333", "YDL052C", "P32660", "YER166W", "P39524", "YAL026C", "Q12675", "YDR093W", "Q04458", "YMR110C", "P36126", "YKR031C", "P32610", "YEL051W", "P25656", "YCR094W", "Q12674", "YMR162C", "Q12091", "YPL170W", "P40357", "YGR009C", "Q06144", "YLR350W", "P38142", "YBR241C", "P53142", "YGL104C", "P33328", "YOR327C", "P32901", "YKR093W", "Q00776", "YPL259C", "Q04359", "YMR017W", "P53224", "YGR038W", "P31109", "YAL030W", "P13856", "YGR152C", "P33333", "YDL052C", "P32660", "YER166W", "P39524", "YAL026C", "Q12675", "YDR093W", "Q04458", "YMR110C", "P36126", "YKR031C", "P32610", "YEL051W", "P25656", "YCR094W", "Q12674", "YMR162C", "Q12091", "YPL170W" ] }, "reaction_10771236": { "compartment": "compartment_70101", "id": "reaction_10771236", "reactome": "R-SCE-874087", "name": "SGT1 binds HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771232", "species_10771226" ], "products": [ "species_10771234" ], "modifiers": [], "additional_components": [ "P02829", "YPL240C", "P15108", "YMR186W", "YOR057W", "P02829", "YPL240C", "Q08446", "YOR057W", "P15108", "YMR186W" ] }, "reaction_10772405": { "compartment": "compartment_70101", "id": "reaction_10772405", "reactome": "R-SCE-983153", "name": "E1 mediated ubiquitin activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10760634", "species_10772397", "species_29926" ], "products": [ "species_111294", "species_76577", "species_10772399", "species_29926" ], "modifiers": [ [ "species_10772397", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "Q99344", "YPR066W", "P38862", "YHR171W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q99344", "YPR066W", "P38862", "YHR171W", "P22515", "YKL210W", "Q99344", "YPR066W", "P38862", "YHR171W" ] }, "reaction_10770762": { "compartment": "compartment_70101", "id": "reaction_10770762", "reactome": "R-SCE-450348", "name": "Activated human JNKs migrate to nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765974" ], "products": [ "species_10765931" ], "modifiers": [], "additional_components": [ "YPR054W", "YPR054W" ] }, "reaction_10782924": { "compartment": "compartment_876", "id": "reaction_10782924", "reactome": "R-SCE-6798743", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782878" ], "products": [ "species_10782922" ], "modifiers": [], "additional_components": [ "P40462", "YIL137C", "Q06144", "YLR350W", "P32454", "YKL157W", "Q00246", "YKR055W", "P06781", "YNL090W", "P38142", "YBR241C", "Q99260", "YLR262C", "P32563", "YOR270C", "P38065", "YBL037W", "P53224", "YGR038W", "P41810", "YDR238C", "P36017", "YOR089C", "P07560", "YFL005W", "Q00245", "YIL118W", "Q12280", "YPL242C", "P06780", "YPR165W", "P32939", "YML001W", "Q04458", "YMR110C", "P37898", "YHR047C", "P48559", "YNL304W", "P40462", "YIL137C", "Q06144", "YLR350W", "P32454", "YKL157W", "Q00246", "YKR055W", "P06781", "YNL090W", "P38142", "YBR241C", "Q99260", "YLR262C", "P32563", "YOR270C", "P38065", "YBL037W", "P53224", "YGR038W", "P41810", "YDR238C", "P36017", "YOR089C", "P07560", "YFL005W", "Q00245", "YIL118W", "Q12280", "YPL242C", "P06780", "YPR165W", "P32939", "YML001W", "Q04458", "YMR110C", "P37898", "YHR047C", "P48559", "YNL304W" ] }, "reaction_10772402": { "compartment": "compartment_70101", "id": "reaction_10772402", "reactome": "R-SCE-983152", "name": "Transfer of ubiquitin from E1 to E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772356", "species_10772399" ], "products": [ "species_10772358", "species_10772397" ], "modifiers": [ [ "species_10772356", "catalyst" ] ], "additional_components": [ "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P22515", "YKL210W", "P15732", "YDR059C", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P52491", "YLR306W", "P21734", "YDR177W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q99344", "YPR066W", "P38862", "YHR171W", "P22515", "YKL210W", "P15732", "YDR059C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P05759", "RPS31", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52491", "YLR306W", "P21734", "YDR177W", "P22515", "YKL210W", "Q99344", "YPR066W", "P38862", "YHR171W", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P22515", "YKL210W", "P15732", "YDR059C", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P52491", "YLR306W", "P21734", "YDR177W" ] }, "reaction_10774030": { "compartment": "compartment_70101", "id": "reaction_10774030", "reactome": "R-SCE-2029454", "name": "Autophosphorylation of PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774023", "species_113592" ], "products": [ "species_29370", "species_10774027", "species_10768894" ], "modifiers": [ [ "species_10768970", "catalyst" ] ], "additional_components": [ "Q03497", "YHL007C", "species_29438", "P19073", "YLR229C", "YHL007C", "species_29438", "P19073", "YLR229C", "YHL007C" ] }, "reaction_10774276": { "compartment": "compartment_70101", "id": "reaction_10774276", "reactome": "R-SCE-2317332", "name": "PIP3 recruits AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10769080" ], "products": [ "species_10767182" ], "modifiers": [], "additional_components": [ "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "P11792", "YHR205W" ] }, "reaction_10772383": { "compartment": "compartment_70101", "id": "reaction_10772383", "reactome": "R-SCE-983150", "name": "Proteasomal cleavage of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983123" ], "products": [ "species_983032", "species_983036", "species_10760634", "species_8942986" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10784185": { "compartment": "compartment_984", "id": "reaction_10784185", "reactome": "R-SCE-6804100", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784177", "species_166005" ], "products": [ "species_10784183" ], "modifiers": [], "additional_components": [ "YBR089C-A", "species_166005", "P11633", "YBR089C-A" ] }, "reaction_10774162": { "compartment": "compartment_161320", "id": "reaction_10774162", "reactome": "R-SCE-2130706", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2213225" ], "products": [ "species_2213226" ], "modifiers": [ [ "species_10774157", "catalyst" ] ], "additional_components": [ "YPL154C" ] }, "reaction_10784181": { "compartment": "compartment_984", "id": "reaction_10784181", "reactome": "R-SCE-6804099", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784177", "species_181015" ], "products": [ "species_10784179" ], "modifiers": [], "additional_components": [ "YBR089C-A", "P11633", "YBR089C-A", "species_181015" ] }, "reaction_10770513": { "compartment": "compartment_70101", "id": "reaction_10770513", "reactome": "R-SCE-446877", "name": "TRAF6 is K63 poly-ubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770504" ], "products": [ "species_10770510" ], "modifiers": [ [ "species_10770504", "catalyst" ] ], "additional_components": [ "P43633", "YGL021W", "P32789", "YBL009W", "P05759", "RPS31", "P53152", "MMS2", "P52490", "UBC13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P43633", "YGL021W", "P32789", "YBL009W", "P53152", "MMS2", "P52490", "UBC13", "P43633", "YGL021W", "P32789", "YBL009W", "P05759", "RPS31", "P53152", "MMS2", "P52490", "UBC13", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10787872": { "compartment": "compartment_984", "id": "reaction_10787872", "reactome": "R-SCE-9008043", "name": "MAPK8 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10765968" ], "products": [ "species_29370", "species_10765974" ], "modifiers": [], "additional_components": [ "YPR054W", "YPR054W" ] }, "reaction_10772410": { "compartment": "compartment_70101", "id": "reaction_10772410", "reactome": "R-SCE-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772358", "species_10772267", "species_983035" ], "products": [ "species_10772360" ], "modifiers": [], "additional_components": [ "P22515", "YKL210W", "P15732", "YDR059C", "P52490", "UBC13", "P28263", "YEL012W", "Q02159", "YMR022W", "P33296", "YER100W", "P52492", "YOR339C", "P15731", "YBR082C", "P05759", "RPS31", "P06104", "YGL058W", "P53152", "MMS2", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52491", "YLR306W", "P21734", "YDR177W", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P13365", "YAL040C", "Q08273", "YOL133W", "P22515", "YKL210W", "P15732", "YDR059C", "P38042", "YBL084C", "P52490", "UBC13", "Q04601", "YDR118W", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P52492", "YOR339C", "P06104", "YGL058W", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P0CH08", "RPL40A", "P53197", "YGL003C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "P52286", "YDR328C", "P28263", "YEL012W", "P54860", "YDL190C", "P26309", "YGL116W", "P33296", "YER100W", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P05759", "RPS31", "P53152", "MMS2", "Q03280", "YDR457W", "P0CH09", "RPL40B", "Q07963", "YLR024C", "P20437", "YMR199W", "P21734", "YDR177W", "P53886", "YNL172W", "P39940", "YER125W", "Q12018", "YDL132W", "P24868", "YGR108W", "Q02159", "YMR022W", "Q05164", "YOL155C", "P15731", "YBR082C", "P24869", "YPR119W", "P25382", "YCR072C", "P52491", "YLR306W", "P19812", "YGR184C", "Q08683", "YOR249C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P32943", "YGR109C", "P14682", "YDR054C", "P30283", "YPR120C", "P16522", "YHR166C", "Q12347", "YLR097C" ] }, "reaction_10772644": { "compartment": "compartment_70101", "id": "reaction_10772644", "reactome": "R-SCE-1236970", "name": "Proteasomal clevage of exogenous antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236719" ], "products": [ "species_983036", "species_8942986" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10765954": { "compartment": "compartment_7660", "id": "reaction_10765954", "reactome": "R-SCE-168053", "name": "Phosphorylated MAPKs phosphorylate ATF-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10765901" ], "products": [ "species_113582", "species_10765915" ], "modifiers": [ [ "species_10765951", "catalyst" ] ], "additional_components": [ "P39970", "YER045C", "P40535", "YIL036W", "Q02100", "YNL167C", "P39970", "YER045C", "P40535", "YIL036W", "Q02100", "YNL167C", "P16892", "YBL016W", "P41808", "YPR054W", "Q00772", "YHR030C", "P32485", "YLR113W", "P14681", "YGR040W" ] }, "reaction_10784297": { "compartment": "compartment_984", "id": "reaction_10784297", "reactome": "R-SCE-6805981", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768264" ], "products": [ "species_10784177" ], "modifiers": [], "additional_components": [ "YBR089C-A", "YBR089C-A" ] }, "reaction_10769000": { "compartment": "compartment_70101", "id": "reaction_10769000", "reactome": "R-SCE-389788", "name": "Activation of PAKs by RAC1 and CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768994", "species_10768894" ], "products": [ "species_10768996", "species_10768998" ], "modifiers": [], "additional_components": [ "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "species_29438", "P19073", "YLR229C", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W", "P48562", "YNL298W", "Q03497", "YHL007C", "species_29438", "Q12469", "YOL113W", "P19073", "YLR229C" ] }, "reaction_10770707": { "compartment": "compartment_70101", "id": "reaction_10770707", "reactome": "R-SCE-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770683" ], "products": [ "species_10770705" ], "modifiers": [], "additional_components": [ "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10772381": { "compartment": "compartment_70101", "id": "reaction_10772381", "reactome": "R-SCE-983147", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772379" ], "products": [ "species_10772267", "species_983123" ], "modifiers": [], "additional_components": [ "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C", "P13365", "YAL040C", "Q08273", "YOL133W", "P39940", "YER125W", "Q12018", "YDL132W", "P38042", "YBL084C", "P24868", "YGR108W", "Q04601", "YDR118W", "Q05164", "YOL155C", "P09798", "YKL022C", "Q04511", "YML088W", "P36113", "YKR017C", "P53068", "YGL240W", "Q12157", "YDL008W", "Q04638", "YML068W", "P24869", "YPR119W", "P53197", "YGL003C", "P25382", "YCR072C", "P19812", "YGR184C", "P07248", "YDR216W", "P36037", "YKL213C", "P40578", "YIR033W", "P40442", "YIL169C", "Q08683", "YOR249C", "P52286", "YDR328C", "Q04781", "YMR247C", "P53202", "YGR003W", "P53119", "YGL141W", "P54860", "YDL190C", "P26309", "YGL116W", "P33202", "YKL010C", "P20438", "YPL256C", "Q12440", "YLR127C", "P35728", "YKL059C", "P47172", "YJR141W", "Q03071", "YPL046C", "P35210", "YKL020C", "P32943", "YGR109C", "Q03280", "YDR457W", "Q07963", "YLR024C", "P30283", "YPR120C", "P20437", "YMR199W", "P16522", "YHR166C", "P53886", "YNL172W", "Q12347", "YLR097C" ] }, "reaction_10767125": { "compartment": "compartment_876", "id": "reaction_10767125", "reactome": "R-SCE-198314", "name": "DAG stimulates protein kinase C-delta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767110", "species_113592" ], "products": [ "species_29370", "species_10767117" ], "modifiers": [ [ "species_10767110", "catalyst" ], [ "species_112275", "catalyst" ] ], "additional_components": [ "YBL105C", "YBL105C", "YBL105C" ] }, "reaction_10782803": { "compartment": "compartment_6798757", "id": "reaction_10782803", "reactome": "R-SCE-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782785" ], "products": [ "species_10782801" ], "modifiers": [], "additional_components": [ "P40357", "YGR009C", "P33767", "YEL002C", "P33328", "YOR327C", "Q03723", "YML019W", "P25515", "YEL027W", "P31109", "YAL030W", "P13856", "YGR152C", "P07560", "YFL005W", "P53337", "YGR284C", "P39524", "YAL026C", "P48439", "YOR085W", "P40075", "YER120W", "P25656", "YCR094W", "Q12674", "YMR162C", "P40357", "YGR009C", "P33767", "YEL002C", "P33328", "YOR327C", "Q03723", "YML019W", "P25515", "YEL027W", "P31109", "YAL030W", "P13856", "YGR152C", "P07560", "YFL005W", "P53337", "YGR284C", "P39524", "YAL026C", "P48439", "YOR085W", "P40075", "YER120W", "P25656", "YCR094W", "Q12674", "YMR162C" ] }, "reaction_10784060": { "compartment": "compartment_984", "id": "reaction_10784060", "reactome": "R-SCE-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784052" ], "products": [ "species_10784058" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "Q06625", "YPR184W", "P32807", "YMR284W", "P25043", "YOR157C", "P06738", "YPR160W", "P02994", "YBR118W", "P47103", "YJR032W", "Q03957", "YKL139W", "P04806", "YFR053C", "Q12096", "YOR320C", "Q03262", "YMR278W", "P38764", "YHR027C", "Q04120", "YDR453C", "P52489", "YOR347C", "Q08723", "YOR261C", "P38930", "CKB2", "P12709", "YBR196C", "P36010", "YKL067W", "P34760", "YML028W", "P32485", "YLR113W", "P32381", "YDL029W", "P32379", "YGR253C", "P38696", "YHR129C", "P16862", "YMR205C", "P40361", "YJL070C", "P25694", "YDL126C", "P15202", "YDR256C", "P46958", "YJL146W", "P47011", "YJL137C", "Q06142", "YLR347C", "Q06103", "YPR108W", "P21954", "YDL066W", "P16861", "YGR240C", "P17709", "YCL040W", "P23724", "YBL041W", "P33401", "YKL127W", "P50094", "YML056C", "P15274", "YML035C", "P33297", "YOR117W", "Q06204", "YLR446W", "Q10740", "YNL045W", "Q03280", "YDR457W", "P38985", "YDL092W", "Q12377", "YDL097C", "P10592", "YLL024C", "P47079", "YJL008C", "P11633", "YBR089C-A", "P16892", "YBL016W", "P32769", "YKR084C", "Q06549", "YLR245C", "P15891", "YCR088W", "Q12250", "YDL147W", "P04807", "YGL253W", "P00549", "YAL038W", "P50095", "YLR432W", "Q08491", "SKI7", "P23639", "YML092C", "Q12156", "YDR063W", "P53691", "YLR216C", "P32324", "EFT2", "P38697", "YHR216W", "P02829", "YPL240C", "P05373", "YGL040C", "Q05788", "YLR209C", "P06634", "YOR204W", "P38862", "YHR171W", "P40518", "YIL062C", "Q04409", "YDR516C", "P38150", "YJL070C", "Q04062", "YDR427W", "P33299", "YKL145W", "P32464", "YKL189W", "P43599", "YFR018C", "P07267", "YPL154C", "P40016", "YER021W", "P15108", "YMR186W", "P43588", "YFR004W", "P36143", "YKR058W", "P06787", "YBR109C", "Q06625", "YPR184W", "P32807", "YMR284W", "P25043", "YOR157C", "P06738", "YPR160W", "P02994", "YBR118W", "P47103", "YJR032W", "Q03957", "YKL139W", "P04806", "YFR053C", "Q12096", "YOR320C", "Q03262", "YMR278W", "P38764", "YHR027C", "Q04120", "YDR453C", "P52489", "YOR347C", "Q08723", "YOR261C", "P38930", "CKB2", "P12709", "YBR196C", "P36010", "YKL067W", "P34760", "YML028W", "P32485", "YLR113W", "P32381", "YDL029W", "P32379", "YGR253C", "P38696", "YHR129C", "P16862", "YMR205C", "P40361", "YJL070C", "P25694", "YDL126C", "P15202", "YDR256C", "P46958", "YJL146W", "P47011", "YJL137C", "Q06142", "YLR347C", "Q06103", "YPR108W", "P21954", "YDL066W", "P16861", "YGR240C", "P17709", "YCL040W", "P23724", "YBL041W", "P33401", "YKL127W", "P50094", "YML056C", "P15274", "YML035C", "P33297", "YOR117W", "Q06204", "YLR446W", "Q10740", "YNL045W", "Q03280", "YDR457W", "P38985", "YDL092W", "Q12377", "YDL097C", "P10592", "YLL024C", "P47079", "YJL008C", "P11633", "YBR089C-A", "P16892", "YBL016W", "P32769", "YKR084C", "Q06549", "YLR245C", "P15891", "YCR088W", "Q12250", "YDL147W", "P04807", "YGL253W", "P00549", "YAL038W", "P50095", "YLR432W", "Q08491", "SKI7", "P23639", "YML092C", "Q12156", "YDR063W", "P53691", "YLR216C", "P32324", "EFT2", "P38697", "YHR216W", "P02829", "YPL240C", "P05373", "YGL040C", "Q05788", "YLR209C", "P06634", "YOR204W", "P38862", "YHR171W", "P40518", "YIL062C", "Q04409", "YDR516C", "P38150", "YJL070C", "Q04062", "YDR427W", "P33299", "YKL145W", "P32464", "YKL189W", "P43599", "YFR018C", "P07267", "YPL154C", "P40016", "YER021W", "P15108", "YMR186W", "P43588", "YFR004W", "P36143", "YKR058W" ] }, "reaction_10765966": { "compartment": "compartment_7660", "id": "reaction_10765966", "reactome": "R-SCE-168136", "name": "Activated JNKs phosphorylate c-JUN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765959", "species_29358" ], "products": [ "species_10765963", "species_113582" ], "modifiers": [ [ "species_10765931", "catalyst" ] ], "additional_components": [ "YEL009C", "YEL009C", "YPR054W" ] }, "reaction_10772458": { "compartment": "compartment_70101", "id": "reaction_10772458", "reactome": "R-SCE-983162", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983036" ], "products": [ "species_983032", "species_8942986" ], "modifiers": [ [ "species_10772455", "catalyst" ] ], "additional_components": [ "P40462", "YIL137C", "P32454", "YKL157W", "P37898", "YHR047C", "Q01532", "YNL239W" ] }, "reaction_10768965": { "compartment": "compartment_70101", "id": "reaction_10768965", "reactome": "R-SCE-389756", "name": "AKT interacts and phosphorylates Cot", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768955", "species_113592" ], "products": [ "species_29370", "species_10768963" ], "modifiers": [ [ "species_10767105", "catalyst" ] ], "additional_components": [ "P25390", "YCR073C", "P53599", "YNR031C", "P25390", "YCR073C", "P53599", "YNR031C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10770645": { "compartment": "compartment_70101", "id": "reaction_10770645", "reactome": "R-SCE-450257", "name": "Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770638" ], "products": [ "species_10770643" ], "modifiers": [], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W" ] }, "reaction_10766862": { "compartment": "compartment_17951", "id": "reaction_10766862", "reactome": "R-SCE-193508", "name": "(24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193732", "species_192307" ], "products": [ "species_193465", "species_193403", "species_192305" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10786503": { "compartment": "compartment_70101", "id": "reaction_10786503", "reactome": "R-SCE-8867667", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399" ], "products": [ "species_8868400" ], "modifiers": [ [ "species_10786500", "catalyst" ] ], "additional_components": [ "P38713", "YHR073W", "Q12451", "YDL019C", "P35845", "YAR042W", "P35844", "YPL145C" ] }, "reaction_10766816": { "compartment": "compartment_70101", "id": "reaction_10766816", "reactome": "R-SCE-191983", "name": "Cholesterol is hydroxylated to 25-hydroxycholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_176478", "species_29368" ], "products": [ "species_29366", "species_192148", "species_29356" ], "modifiers": [ [ "species_10766813", "catalyst" ] ], "additional_components": [ "species_111793", "P53045", "YGR060W" ] }, "reaction_10766860": { "compartment": "compartment_17951", "id": "reaction_10766860", "reactome": "R-SCE-193455", "name": "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193422", "species_192307" ], "products": [ "species_193465", "species_192305", "species_192339" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10766864": { "compartment": "compartment_17951", "id": "reaction_10766864", "reactome": "R-SCE-193535", "name": "25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_193459" ], "products": [ "species_193732" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10766824": { "compartment": "compartment_70101", "id": "reaction_10766824", "reactome": "R-SCE-192097", "name": "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192114", "species_29360" ], "products": [ "species_70106", "species_73473", "species_192136" ], "modifiers": [ [ "species_10766821", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10766868": { "compartment": "compartment_70101", "id": "reaction_10766868", "reactome": "R-SCE-193789", "name": "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192189", "species_29360" ], "products": [ "species_70106", "species_73473", "species_193724" ], "modifiers": [ [ "species_10766821", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10786538": { "compartment": "compartment_70101", "id": "reaction_10786538", "reactome": "R-SCE-8868402", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399", "species_1806217" ], "products": [ "species_1806234", "species_8868393" ], "modifiers": [ [ "species_10786535", "catalyst" ] ], "additional_components": [ "P38713", "YHR073W", "Q12451", "YDL019C", "P35845", "YAR042W" ] }, "reaction_10766870": { "compartment": "compartment_70101", "id": "reaction_10766870", "reactome": "R-SCE-193816", "name": "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192194", "species_29360" ], "products": [ "species_70106", "species_73473", "species_193835" ], "modifiers": [ [ "species_10766821", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10766834": { "compartment": "compartment_17951", "id": "reaction_10766834", "reactome": "R-SCE-192331", "name": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192342", "species_141343" ], "products": [ "species_193422" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10766857": { "compartment": "compartment_17951", "id": "reaction_10766857", "reactome": "R-SCE-193385", "name": "Hydrolysis of choloyl-CoA to cholate and CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192356", "species_141343" ], "products": [ "species_193514", "species_193451" ], "modifiers": [ [ "species_10766854", "catalyst" ] ], "additional_components": [ "YJR019C" ] }, "reaction_10785978": { "compartment": "compartment_5683628", "id": "reaction_10785978", "reactome": "R-SCE-8854588", "name": "TBC1D25 (OATL1) binds ATG8 homologues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779200", "species_10785974" ], "products": [ "species_10785976" ], "modifiers": [], "additional_components": [ "YBL078C", "YDL234C", "P48365", "YDL234C", "P38182", "YBL078C" ] }, "reaction_10786878": { "compartment": "compartment_263163", "id": "reaction_10786878", "reactome": "R-SCE-8876193", "name": "RIC1-RGP1 exchanges GTP for GDP on RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786865", "species_29438" ], "products": [ "species_10786790", "species_10786869", "species_29420" ], "modifiers": [ [ "species_10786875", "catalyst" ] ], "additional_components": [ "species_29420", "Q99260", "YLR262C", "P39958", "YER136W", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "Q99260", "YLR262C", "species_29438", "P16664", "YDR137W", "P40395", "YLR039C" ] }, "reaction_10785971": { "compartment": "compartment_17938", "id": "reaction_10785971", "reactome": "R-SCE-8854329", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785946", "species_29356" ], "products": [ "species_10785964", "species_29372" ], "modifiers": [ [ "species_10785946", "catalyst" ], [ "species_10785969", "catalyst" ] ], "additional_components": [ "P32939", "YML001W", "CHEBI:15996", "P32939", "YML001W", "species_111349", "P32939", "YML001W", "CHEBI:15996", "YDL234C" ] }, "reaction_10785951": { "compartment": "compartment_17938", "id": "reaction_10785951", "reactome": "R-SCE-8854255", "name": "TBC1D2A accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785946", "species_29356" ], "products": [ "species_29372", "species_10785948" ], "modifiers": [ [ "species_10785946", "catalyst" ] ], "additional_components": [ "P32939", "YML001W", "CHEBI:15996", "species_29420", "P32939", "YML001W", "P32939", "YML001W", "CHEBI:15996" ] }, "reaction_10786851": { "compartment": "compartment_263163", "id": "reaction_10786851", "reactome": "R-SCE-8876190", "name": "RAB8 GEFs exchange GTP for GDP on RAB8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10786842" ], "products": [ "species_10786790", "species_10786848", "species_29420" ], "modifiers": [ [ "species_10778221", "catalyst" ] ], "additional_components": [ "species_29420", "P07560", "YFL005W", "P39958", "YER136W", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "P07560", "YFL005W", "species_29438", "YNL272C" ] }, "reaction_10785960": { "compartment": "compartment_20699", "id": "reaction_10785960", "reactome": "R-SCE-8854303", "name": "TBC1D11 binds RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785468", "species_10785956" ], "products": [ "species_10785958" ], "modifiers": [], "additional_components": [ "Q99260", "YLR262C", "species_29438", "YPL249C", "Q99260", "YLR262C", "Q12344", "YPL249C", "species_29438" ] }, "reaction_10786959": { "compartment": "compartment_13946", "id": "reaction_10786959", "reactome": "R-SCE-8877475", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10786946" ], "products": [ "species_10786790", "species_29420", "species_10786956" ], "modifiers": [ [ "species_10781391", "catalyst" ] ], "additional_components": [ "species_29420", "P39958", "YER136W", "P01123", "YFL038C", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "P01123", "YFL038C", "species_29438", "P38334", "YBR254C", "Q03630", "YML077W", "Q03784", "YDR246W", "P36149", "YKR068C", "Q04183", "YDR407C", "Q03337", "YDR472W", "Q03660", "YMR218C", "Q99394", "YOR115C" ] }, "reaction_10786801": { "compartment": "compartment_216813", "id": "reaction_10786801", "reactome": "R-SCE-8875318", "name": "RAB3 GEFs exchange GTP for GDP on RAB3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10786792" ], "products": [ "species_10786790", "species_10786796", "species_29420" ], "modifiers": [ [ "species_10786798", "catalyst" ] ], "additional_components": [ "P07560", "YFL005W", "species_29420", "P39958", "YER136W", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "P07560", "YFL005W", "species_29438", "YNL272C" ] }, "reaction_10786938": { "compartment": "compartment_17938", "id": "reaction_10786938", "reactome": "R-SCE-8877451", "name": "MON1:CCZ1 exchanges GTP for GDP on RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10786915" ], "products": [ "species_10786790", "species_10786921", "species_29420" ], "modifiers": [ [ "species_10786935", "catalyst" ] ], "additional_components": [ "species_29420", "P39958", "YER136W", "P32939", "YML001W", "P32864", "YOR370C", "P39958", "YER136W", "P32864", "YOR370C", "P32939", "YML001W", "species_29438", "P38273", "YBR131W", "P53129", "YGL124C" ] }, "reaction_10771192": { "compartment": "compartment_70101", "id": "reaction_10771192", "reactome": "R-SCE-727749", "name": "SLC29A3 transports nucleosides from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727782" ], "products": [ "species_727746" ], "modifiers": [ [ "species_10771189", "catalyst" ] ], "additional_components": [ "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "species_83951", "CHEBI:16704", "species_83909", "CHEBI:16750", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "species_83951", "CHEBI:16704", "species_83909", "CHEBI:16750", "YAL022C" ] }, "reaction_10764488": { "compartment": "compartment_70101", "id": "reaction_10764488", "reactome": "R-SCE-109534", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179743" ], "products": [ "species_179737" ], "modifiers": [ [ "species_10764480", "catalyst" ] ], "additional_components": [ "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83909", "CHEBI:16750", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83909", "CHEBI:16750", "YAL022C" ] }, "reaction_10765594": { "compartment": "compartment_70616", "id": "reaction_10765594", "reactome": "R-SCE-163215", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113592", "species_113581" ], "modifiers": [ [ "species_10765591", "catalyst" ] ], "additional_components": [ "P18239", "YBL030C", "P18238", "YBR085W", "P04710", "AAC1" ] }, "reaction_10764483": { "compartment": "compartment_70101", "id": "reaction_10764483", "reactome": "R-SCE-109527", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179747" ], "products": [ "species_179742" ], "modifiers": [ [ "species_10764478", "catalyst" ] ], "additional_components": [ "species_113599", "CHEBI:17821", "species_29554", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83951", "species_83909", "CHEBI:16040", "CHEBI:16750", "species_83956", "species_113599", "CHEBI:17821", "species_29554", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83951", "species_83909", "CHEBI:16040", "CHEBI:16750", "species_83956", "YAL022C" ] }, "reaction_10764485": { "compartment": "compartment_70101", "id": "reaction_10764485", "reactome": "R-SCE-109529", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179742" ], "products": [ "species_179747" ], "modifiers": [ [ "species_10764478", "catalyst" ] ], "additional_components": [ "species_113599", "CHEBI:17821", "species_29554", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83951", "species_83909", "CHEBI:16040", "CHEBI:16750", "species_83956", "species_113599", "CHEBI:17821", "species_29554", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83951", "species_83909", "CHEBI:16040", "CHEBI:16750", "species_83956", "YAL022C" ] }, "reaction_10764490": { "compartment": "compartment_70101", "id": "reaction_10764490", "reactome": "R-SCE-109536", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179737" ], "products": [ "species_179743" ], "modifiers": [ [ "species_10764480", "catalyst" ] ], "additional_components": [ "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83909", "CHEBI:16750", "CHEBI:17748", "CHEBI:17596", "CHEBI:17562", "CHEBI:16704", "species_83909", "CHEBI:16750", "YAL022C" ] }, "reaction_10774173": { "compartment": "compartment_5460", "id": "reaction_10774173", "reactome": "R-SCE-2162186", "name": "DeMQ10H2 is methylated to Q10H2 by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162212", "species_2162265" ], "products": [ "species_2162252", "species_2162198", "species_113529" ], "modifiers": [ [ "species_10774170", "catalyst" ] ], "additional_components": [ "YOL096C" ] }, "reaction_10774183": { "compartment": "compartment_5460", "id": "reaction_10774183", "reactome": "R-SCE-2162193", "name": "DHDB is methylated to MHDB by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162209", "species_2162265" ], "products": [ "species_2162252", "species_2162215", "species_113529" ], "modifiers": [ [ "species_10774170", "catalyst" ] ], "additional_components": [ "YOL096C" ] }, "reaction_10774197": { "compartment": "compartment_5460", "id": "reaction_10774197", "reactome": "R-SCE-2162253", "name": "FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162256", "species_2162257" ], "products": [ "species_2162214", "species_159450" ], "modifiers": [ [ "species_10774194", "catalyst" ] ], "additional_components": [ "P18900", "YBR003W", "species_109496" ] }, "reaction_10768904": { "compartment": "compartment_70101", "id": "reaction_10768904", "reactome": "R-SCE-389540", "name": "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_389545" ], "products": [ "species_70106", "species_29364", "species_113528", "species_29406" ], "modifiers": [ [ "species_10768901", "catalyst" ] ], "additional_components": [ "P21954", "YDL066W" ] }, "reaction_10773350": { "compartment": "compartment_70101", "id": "reaction_10773350", "reactome": "R-SCE-1497796", "name": "BH2 binding can lead to eNOS uncoupling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767639", "species_1497857" ], "products": [ "species_29870", "species_10773348" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "P15108", "YMR186W", "species_29870", "species_113596", "P11792", "YHR205W", "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "species_1497857", "species_29870", "P15108", "YMR186W", "species_113596", "P11792", "YHR205W" ] }, "reaction_10772915": { "compartment": "compartment_70101", "id": "reaction_10772915", "reactome": "R-SCE-1474146", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29356" ], "products": [ "species_1474124", "species_29460" ], "modifiers": [ [ "species_10772912", "catalyst" ], [ "species_29502", "catalyst" ], [ "species_29870", "inhibitor" ] ], "additional_components": [ "P51601", "YGR267C" ] }, "reaction_10774180": { "compartment": "compartment_70616", "id": "reaction_10774180", "reactome": "R-SCE-2162192", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162214", "species_2162213" ], "products": [ "species_2162207", "species_159450" ], "modifiers": [ [ "species_10774177", "catalyst" ] ], "additional_components": [] }, "reaction_10781221": { "compartment": "compartment_7660", "id": "reaction_10781221", "reactome": "R-SCE-5693566", "name": "TP53BP1 associates with H4K20Me2 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779351", "species_10774864" ], "products": [ "species_10779374" ], "modifiers": [], "additional_components": [ "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "YDR217C", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P14737", "YDR217C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10777638": { "compartment": "compartment_7660", "id": "reaction_10777638", "reactome": "R-SCE-5358513", "name": "MSH2:MSH3 binds insertion/deletion loop of 2 bases or more", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358527", "species_10777634" ], "products": [ "species_10777636" ], "modifiers": [], "additional_components": [ "P25336", "YCR092C", "species_29370", "P25847", "YOL090W", "P25336", "YCR092C", "species_29370", "P25847", "YOL090W" ] }, "reaction_10781856": { "compartment": "compartment_7660", "id": "reaction_10781856", "reactome": "R-SCE-6782211", "name": "DNA polymerases delta, epsilon or kappa bind the TC-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781852", "species_10760923", "species_10764822", "species_10781840" ], "products": [ "species_10781854" ], "modifiers": [], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P15873", "YBR088C", "P40348", "YJR068W", "P38630", "YOR217W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "P40366", "YJL065C", "P27344", "YBR278W", "Q04603", "YDR121W", "P24482", "YPR175W", "P21951", "YNL262W", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P22336", "YAR007C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P06777", "YPL022W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P26754", "YNL312W", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P22336", "YAR007C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P32523", "YLL036C", "P0CH08", "RPL40A", "P07273", "YGL043W", "P38251", "YBR087W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "P28519", "YMR201C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P06777", "YPL022W", "Q04048", "YDR416W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P26754", "YNL312W", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10778491": { "compartment": "compartment_7660", "id": "reaction_10778491", "reactome": "R-SCE-5655466", "name": "USP1:WDR48 deubiquitinates monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778486" ], "products": [ "species_10778488", "species_10778482", "species_10760537" ], "modifiers": [ [ "species_10778486", "catalyst" ] ], "additional_components": [ "P38630", "YOR217W", "P40339", "YOL094C", "Q99247", "YOL087C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P36026", "YKR098C", "P26754", "YNL312W", "P25037", "YDL122W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P39967", "YER098W", "P15873", "YBR088C", "P40453", "YIL156W", "P38187", "YBL067C", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P36026", "YKR098C", "Q99247", "YOL087C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38630", "YOR217W", "P40339", "YOL094C", "Q99247", "YOL087C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P36026", "YKR098C", "P26754", "YNL312W", "P25037", "YDL122W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P39967", "YER098W", "P15873", "YBR088C", "P40453", "YIL156W", "P38187", "YBL067C" ] }, "reaction_10777795": { "compartment": "compartment_7660", "id": "reaction_10777795", "reactome": "R-SCE-5444511", "name": "Formation of MSH2:MSH3 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10777614", "species_10777632" ], "products": [ "species_10777634" ], "modifiers": [], "additional_components": [ "YOL090W", "YCR092C", "P25336", "YCR092C", "species_29370", "P25847", "YOL090W" ] }, "reaction_10779178": { "compartment": "compartment_7660", "id": "reaction_10779178", "reactome": "R-SCE-5682044", "name": "KAT5 acetylates ATM at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779173", "species_113560" ], "products": [ "species_10779175", "species_2485002" ], "modifiers": [ [ "species_10779173", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10781860": { "compartment": "compartment_7660", "id": "reaction_10781860", "reactome": "R-SCE-6782227", "name": "Ligation of newly synthesized repair patch to incised DNA in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781847" ], "products": [ "species_10781049", "species_10781858" ], "modifiers": [ [ "species_10760994", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P38251", "YBR087W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "P22336", "YAR007C", "P40348", "YJR068W", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P38251", "YBR087W", "P38629", "YNL290W", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "YDL164C" ] }, "reaction_10781753": { "compartment": "compartment_7660", "id": "reaction_10781753", "reactome": "R-SCE-6781867", "name": "ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781734", "species_10760537" ], "products": [ "species_10781750" ], "modifiers": [ [ "species_10781734", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P0CH08", "RPL40A", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "P40422", "RPC10", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10764704": { "compartment": "compartment_7660", "id": "reaction_10764704", "reactome": "R-SCE-110226", "name": "Cleavage of cytosine glycol by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764701" ], "products": [ "species_110225", "species_10764694" ], "modifiers": [ [ "species_10764701", "catalyst" ] ], "additional_components": [ "Q08214", "YOL043C", "Q08214", "YOL043C", "Q08214", "YOL043C" ] }, "reaction_10764171": { "compartment": "compartment_7660", "id": "reaction_10764171", "reactome": "R-SCE-75998", "name": "Formation of RAD52 heptameric ring structure complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764167" ], "products": [ "species_10764169" ], "modifiers": [], "additional_components": [ "YML032C", "P06778", "YML032C" ] }, "reaction_10764737": { "compartment": "compartment_7660", "id": "reaction_10764737", "reactome": "R-SCE-110244", "name": "Excision of FapyG by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764734" ], "products": [ "species_10764729", "species_5636006" ], "modifiers": [ [ "species_10764734", "catalyst" ] ], "additional_components": [ "P53397", "YML060W", "P53397", "YML060W", "P53397", "YML060W" ] }, "reaction_10781817": { "compartment": "compartment_7660", "id": "reaction_10781817", "reactome": "R-SCE-6782131", "name": "ERCC2-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781803" ], "products": [ "species_113582", "species_113550", "species_10781814" ], "modifiers": [ [ "species_10781803", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10779347": { "compartment": "compartment_7660", "id": "reaction_10779347", "reactome": "R-SCE-5682983", "name": "ATM phosphorylates WHSC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779342" ], "products": [ "species_113582", "species_10779337" ], "modifiers": [ [ "species_10779342", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10779385": { "compartment": "compartment_7660", "id": "reaction_10779385", "reactome": "R-SCE-5683425", "name": "ATM phosphorylates TP53BP1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779374" ], "products": [ "species_113582", "species_10779372" ], "modifiers": [ [ "species_10779374", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P14737", "YDR217C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P14737", "YDR217C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P14737", "YDR217C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10779325": { "compartment": "compartment_7660", "id": "reaction_10779325", "reactome": "R-SCE-5682858", "name": "RNF8 and RNF168 ubiquitinate H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779300", "species_10760537" ], "products": [ "species_10779322" ], "modifiers": [ [ "species_10779300", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10764711": { "compartment": "compartment_7660", "id": "reaction_10764711", "reactome": "R-SCE-110227", "name": "Cleavage of dihydrouracil by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764708" ], "products": [ "species_30140", "species_10764694" ], "modifiers": [ [ "species_10764708", "catalyst" ] ], "additional_components": [ "Q08214", "YOL043C", "Q08214", "YOL043C", "Q08214", "YOL043C" ] }, "reaction_10779340": { "compartment": "compartment_7660", "id": "reaction_10779340", "reactome": "R-SCE-5682965", "name": "WHSC1 dimethylates histone H4 on lysine K21 at DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779337", "species_77087" ], "products": [ "species_10779251", "species_77502" ], "modifiers": [ [ "species_10779337", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10779472": { "compartment": "compartment_7660", "id": "reaction_10779472", "reactome": "R-SCE-5685230", "name": "CHEK1 phosphorylates RAD51", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779467", "species_29358" ], "products": [ "species_113582", "species_10779470" ], "modifiers": [ [ "species_10761086", "catalyst" ] ], "additional_components": [ "YER095W", "YER095W", "P36002", "YKL198C", "P47116", "YJR059W", "P06782", "YDR477W" ] }, "reaction_10777660": { "compartment": "compartment_7660", "id": "reaction_10777660", "reactome": "R-SCE-5358597", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777656", "species_10777640" ], "products": [ "species_10777658" ], "modifiers": [], "additional_components": [ "YOR033C", "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W", "P14242", "YNL082W", "P38920", "YMR167W", "P39875", "YOR033C", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W" ] }, "reaction_10763954": { "compartment": "compartment_7660", "id": "reaction_10763954", "reactome": "R-SCE-75172", "name": "Formation of RAD50:MRE11 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763950", "species_981774" ], "products": [ "species_10763952" ], "modifiers": [], "additional_components": [ "P32829", "MRE11", "P12753", "DNA repair protein RAD50" ] }, "reaction_10777627": { "compartment": "compartment_7660", "id": "reaction_10777627", "reactome": "R-SCE-5358510", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777623", "species_10777609", "species_10760934" ], "products": [ "species_10777625" ], "modifiers": [], "additional_components": [ "species_113592", "Q03834", "YDR097C", "P25847", "YOL090W", "P14242", "YNL082W", "P38920", "YMR167W", "P15873", "YBR088C", "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W" ] }, "reaction_10779284": { "compartment": "compartment_7660", "id": "reaction_10779284", "reactome": "R-SCE-5682607", "name": "PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10779267" ], "products": [ "species_10774805", "species_10779281" ], "modifiers": [ [ "species_10779267", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "YDL064W", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10781725": { "compartment": "compartment_7660", "id": "reaction_10781725", "reactome": "R-SCE-6781840", "name": "ERCC6 binds stalled RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781721", "species_10781713" ], "products": [ "species_10781723" ], "modifiers": [], "additional_components": [ "YJR035W", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P20434", "RPB5", "P40352", "YJR035W", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10779259": { "compartment": "compartment_7660", "id": "reaction_10779259", "reactome": "R-SCE-5682588", "name": "RNF8 binds phosphorylated MDC1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779220", "species_10779255" ], "products": [ "species_10779257" ], "modifiers": [], "additional_components": [ "P53924", "YNL116W", "species_158417", "P32829", "MRE11", "P46995", "YJL168C", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10764718": { "compartment": "compartment_7660", "id": "reaction_10764718", "reactome": "R-SCE-110229", "name": "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764715" ], "products": [ "species_5637659", "species_10764694" ], "modifiers": [ [ "species_10764715", "catalyst" ] ], "additional_components": [ "Q08214", "YOL043C", "Q08214", "YOL043C", "Q08214", "YOL043C" ] }, "reaction_10779296": { "compartment": "compartment_7660", "id": "reaction_10779296", "reactome": "R-SCE-5682629", "name": "HERC2 facilitates UBE2N:UBE2V2 binding to RNF8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779290", "species_10779281" ], "products": [ "species_10779294" ], "modifiers": [], "additional_components": [ "P53152", "MMS2", "P52490", "UBC13", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10778520": { "compartment": "compartment_7660", "id": "reaction_10778520", "reactome": "R-SCE-5655483", "name": "USP1 autocleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778482" ], "products": [ "species_10778480", "species_10778517", "species_10778505" ], "modifiers": [ [ "species_10778482", "catalyst" ] ], "additional_components": [ "P36026", "YKR098C", "Q99247", "YOL087C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "YOL087C", "P36026", "YKR098C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "P36026", "YKR098C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "P36026", "YKR098C", "Q99247", "YOL087C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C" ] }, "reaction_10779349": { "compartment": "compartment_7660", "id": "reaction_10779349", "reactome": "R-SCE-5682992", "name": "KDM4A,B bind H4K20Me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779253", "species_10779251" ], "products": [ "species_10779255" ], "modifiers": [], "additional_components": [ "Q03833", "YDR096W", "P39956", "YER169W", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10781843": { "compartment": "compartment_7660", "id": "reaction_10781843", "reactome": "R-SCE-6782204", "name": "5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781838" ], "products": [ "species_10781840" ], "modifiers": [ [ "species_10781838", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P06777", "YPL022W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P22336", "YAR007C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P06777", "YPL022W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P26754", "YNL312W", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P06777", "YPL022W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P07276", "YGR258C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10781711": { "compartment": "compartment_7660", "id": "reaction_10781711", "reactome": "R-SCE-6781818", "name": "RNA Pol II initiates transcription from damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762310", "species_5688114", "species_10763293" ], "products": [ "species_10781709" ], "modifiers": [], "additional_components": [ "P20433", "YJL140W", "P20434", "RPB5", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P20435", "RPO26", "P04050", "YDL140C", "P40422", "RPC10", "P38902", "YOL005C", "P34087", "YDR404C", "P22139", "RPB10", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10781209": { "compartment": "compartment_7660", "id": "reaction_10781209", "reactome": "R-SCE-5693536", "name": "ATM phosphorylates MDC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781206" ], "products": [ "species_113582", "species_10779335" ], "modifiers": [ [ "species_10781206", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10764732": { "compartment": "compartment_7660", "id": "reaction_10764732", "reactome": "R-SCE-110243", "name": "Excision of 8-oxoguanine by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764727" ], "products": [ "species_10764729", "species_110242" ], "modifiers": [ [ "species_10764727", "catalyst" ] ], "additional_components": [ "P53397", "YML060W", "P53397", "YML060W", "P53397", "YML060W" ] }, "reaction_10781219": { "compartment": "compartment_7660", "id": "reaction_10781219", "reactome": "R-SCE-5693549", "name": "ATM phosphorylates histone H2AFX on S139 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781216" ], "products": [ "species_113582", "species_10779442" ], "modifiers": [ [ "species_10781216", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10781716": { "compartment": "compartment_7660", "id": "reaction_10781716", "reactome": "R-SCE-6781824", "name": "Active RNA Pol II complex transcribes lesion-containing DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781709", "species_6781829" ], "products": [ "species_10781713", "species_113541" ], "modifiers": [ [ "species_10781709", "catalyst" ] ], "additional_components": [ "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10788944": { "compartment": "compartment_70101", "id": "reaction_10788944", "reactome": "R-SCE-9656947", "name": "OGG1beta translocates to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788940" ], "products": [ "species_10788942" ], "modifiers": [], "additional_components": [ "YML060W", "YML060W" ] }, "reaction_10777662": { "compartment": "compartment_7660", "id": "reaction_10777662", "reactome": "R-SCE-5358912", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10777647" ], "products": [ "species_113582", "species_10777623" ], "modifiers": [], "additional_components": [ "species_29370", "Q03834", "YDR097C", "P25847", "YOL090W", "species_113592", "Q03834", "YDR097C", "P25847", "YOL090W" ] }, "reaction_10781224": { "compartment": "compartment_7660", "id": "reaction_10781224", "reactome": "R-SCE-5693598", "name": "ATM phosphorylates NBN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781211" ], "products": [ "species_113582", "species_10779232" ], "modifiers": [ [ "species_10781211", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10779344": { "compartment": "compartment_7660", "id": "reaction_10779344", "reactome": "R-SCE-5682967", "name": "WHSC1 binds DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776856", "species_10779335" ], "products": [ "species_10779342" ], "modifiers": [], "additional_components": [ "YJL168C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P46995", "YJL168C", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10779366": { "compartment": "compartment_7660", "id": "reaction_10779366", "reactome": "R-SCE-5683077", "name": "RNF8 and RNF168 ubiquitinate KDM4A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779322", "species_10760537" ], "products": [ "species_10779351", "species_10779363" ], "modifiers": [ [ "species_10779322", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "Q03833", "YDR096W", "P39956", "YER169W", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10781240": { "compartment": "compartment_7660", "id": "reaction_10781240", "reactome": "R-SCE-5693602", "name": "ATM recognizes H2AFX-Nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779432", "species_10779232" ], "products": [ "species_10781216" ], "modifiers": [], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P02294", "YBL002W", "P02309", "YBR009C", "P34218", "YBL052C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P38110", "YBL088C" ] }, "reaction_10764697": { "compartment": "compartment_7660", "id": "reaction_10764697", "reactome": "R-SCE-110224", "name": "Cleavage of thymine glycol by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764692" ], "products": [ "species_110223", "species_10764694" ], "modifiers": [ [ "species_10764692", "catalyst" ] ], "additional_components": [ "Q08214", "YOL043C", "Q08214", "YOL043C", "Q08214", "YOL043C" ] }, "reaction_10781214": { "compartment": "compartment_7660", "id": "reaction_10781214", "reactome": "R-SCE-5693540", "name": "MRN activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779175", "species_29358" ], "products": [ "species_113582", "species_10781211", "species_10768327" ], "modifiers": [ [ "species_10779175", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10764681": { "compartment": "compartment_7660", "id": "reaction_10764681", "reactome": "R-SCE-110215", "name": "Cleavage of uracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764674" ], "products": [ "species_29554", "species_10764678" ], "modifiers": [ [ "species_10764674", "catalyst" ] ], "additional_components": [ "P12887", "YML021C", "P12887", "YML021C", "P12887", "YML021C" ] }, "reaction_10777649": { "compartment": "compartment_7660", "id": "reaction_10777649", "reactome": "R-SCE-5358525", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358514", "species_10777645" ], "products": [ "species_10777647" ], "modifiers": [], "additional_components": [ "species_29370", "Q03834", "YDR097C", "P25847", "YOL090W", "species_29370", "Q03834", "YDR097C", "P25847", "YOL090W" ] }, "reaction_10777799": { "compartment": "compartment_7660", "id": "reaction_10777799", "reactome": "R-SCE-5444523", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777607", "species_10777602" ], "products": [ "species_10777609" ], "modifiers": [], "additional_components": [ "YNL082W", "YMR167W", "P14242", "YNL082W", "P38920", "YMR167W" ] }, "reaction_10779382": { "compartment": "compartment_7660", "id": "reaction_10779382", "reactome": "R-SCE-5683405", "name": "PPP5C dephosphorylates TP53BP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10779372" ], "products": [ "species_113550", "species_10779374" ], "modifiers": [ [ "species_10779379", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P14737", "YDR217C", "P34218", "YBL052C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "species_158417", "P46995", "YJL168C", "Q12306", "YDR510W", "P52490", "UBC13", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P53924", "YNL116W", "Q04195", "YDR409W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P14737", "YDR217C", "P53152", "MMS2", "P36012", "YKL049C", "P38110", "YBL088C", "YGR123C" ] }, "reaction_10781806": { "compartment": "compartment_7660", "id": "reaction_10781806", "reactome": "R-SCE-6782069", "name": "UVSSA:USP7 deubiquitinates ERCC6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781797", "species_113518" ], "products": [ "species_10781803", "species_10760537" ], "modifiers": [ [ "species_10781797", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10781850": { "compartment": "compartment_7660", "id": "reaction_10781850", "reactome": "R-SCE-6782208", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781845", "species_30555" ], "products": [ "species_10781847", "species_113541" ], "modifiers": [ [ "species_10781845", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P38251", "YBR087W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P38251", "YBR087W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P40339", "YOL094C", "P38902", "YOL005C", "Q04673", "YLR005W", "P22336", "YAR007C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P38251", "YBR087W", "P0CH08", "RPL40A", "P32523", "YLL036C", "P07273", "YGL043W", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "P38630", "YOR217W", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P38629", "YNL290W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "P16370", "YIL021W", "Q03290", "YDR460W", "P40348", "YJR068W", "P05759", "RPS31", "P36106", "YKL005C", "P26754", "YNL312W", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10777797": { "compartment": "compartment_7660", "id": "reaction_10777797", "reactome": "R-SCE-5444516", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10777619", "species_10777614" ], "products": [ "species_10777645" ], "modifiers": [], "additional_components": [ "YDR097C", "YOL090W", "species_29370", "Q03834", "YDR097C", "P25847", "YOL090W" ] }, "reaction_10777643": { "compartment": "compartment_7660", "id": "reaction_10777643", "reactome": "R-SCE-5358518", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777625" ], "products": [ "species_10777640" ], "modifiers": [ [ "species_10777625", "catalyst" ] ], "additional_components": [ "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W", "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W", "P14242", "YNL082W", "P38920", "YMR167W", "species_113592", "Q03834", "YDR097C", "P15873", "YBR088C", "P25847", "YOL090W" ] }, "reaction_10789082": { "compartment": "compartment_7660", "id": "reaction_10789082", "reactome": "R-SCE-9684118", "name": "ERCC3-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10781814" ], "products": [ "species_113582", "species_113550", "species_10781825" ], "modifiers": [ [ "species_10781814", "catalyst" ] ], "additional_components": [ "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C", "Q08273", "YOL133W", "P20434", "RPB5", "P20435", "RPO26", "P50101", "YMR304W", "P38902", "YOL005C", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "P21374", "YJR050W", "P0CH08", "RPL40A", "P07273", "YGL043W", "P32523", "YLL036C", "P22139", "RPB10", "P40352", "YJR035W", "P04050", "YDL140C", "P47050", "YJL047C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P28519", "YMR201C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q04048", "YDR416W", "Q03290", "YDR460W", "P16370", "YIL021W", "P05759", "RPS31", "P36106", "YKL005C", "P40422", "RPC10", "P0CH09", "RPL40B", "P34087", "YDR404C", "P06839", "RAD3", "Q12021", "YDR030C" ] }, "reaction_10779270": { "compartment": "compartment_7660", "id": "reaction_10779270", "reactome": "R-SCE-5682598", "name": "ATM phosphorylates HERC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779263" ], "products": [ "species_113582", "species_10779267" ], "modifiers": [ [ "species_10779263", "catalyst" ] ], "additional_components": [ "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C", "P32829", "MRE11", "P46995", "YJL168C", "species_158417", "Q03833", "YDR096W", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P39956", "YER169W", "Q04195", "YDR409W", "P53924", "YNL116W", "P12753", "DNA repair protein RAD50", "P02294", "YBL002W", "P02309", "YBR009C", "Q12216", "YOR156C", "P34218", "YBL052C", "P36012", "YKL049C", "P38110", "YBL088C" ] }, "reaction_10777651": { "compartment": "compartment_7660", "id": "reaction_10777651", "reactome": "R-SCE-5358592", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358610", "species_29358" ], "products": [ "species_109966", "species_164121", "species_113541" ], "modifiers": [ [ "species_10760994", "catalyst" ] ], "additional_components": [ "YDL164C" ] }, "reaction_10778493": { "compartment": "compartment_7660", "id": "reaction_10778493", "reactome": "R-SCE-5655481", "name": "USP1:WDR48 binds monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778484", "species_10778482" ], "products": [ "species_10778486" ], "modifiers": [], "additional_components": [ "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P38630", "YOR217W", "P26754", "YNL312W", "P40339", "YOL094C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P15873", "YBR088C", "P38629", "YNL290W", "P36026", "YKR098C", "Q99247", "YOL087C", "P25037", "YDL122W", "P39967", "YER098W", "P40453", "YIL156W", "P38187", "YBL067C", "P38630", "YOR217W", "P40339", "YOL094C", "Q99247", "YOL087C", "P38629", "YNL290W", "P22336", "YAR007C", "P40348", "YJR068W", "P05759", "RPS31", "P36026", "YKR098C", "P26754", "YNL312W", "P25037", "YDL122W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P38251", "YBR087W", "P39967", "YER098W", "P15873", "YBR088C", "P40453", "YIL156W", "P38187", "YBL067C" ] }, "reaction_10764688": { "compartment": "compartment_7660", "id": "reaction_10764688", "reactome": "R-SCE-110217", "name": "Cleavage of 5-hydroxyluracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764685" ], "products": [ "species_10764678", "species_110216" ], "modifiers": [ [ "species_10764685", "catalyst" ] ], "additional_components": [ "P12887", "YML021C", "P12887", "YML021C", "P12887", "YML021C" ] }, "reaction_10777996": { "compartment": "compartment_70101", "id": "reaction_10777996", "reactome": "R-SCE-5618331", "name": "HDAC6 deacetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_10777993" ], "products": [ "species_10768744", "species_76183" ], "modifiers": [ [ "species_10777457", "catalyst" ] ], "additional_components": [ "P09734", "YML124C", "species_29420", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "species_29420", "P09734", "YML124C", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "YNL021W" ] }, "reaction_10778225": { "compartment": "compartment_13949", "id": "reaction_10778225", "reactome": "R-SCE-5638014", "name": "RAB11A:GTP-containing Golgi vesicles recruit RAB3IP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778216", "species_10778221" ], "products": [ "species_10778223" ], "modifiers": [], "additional_components": [ "P51996", "YGL210W", "P38555", "YER031C", "species_29438", "YNL272C", "P51996", "YGL210W", "P38555", "YER031C", "species_29438", "P17065", "YNL272C" ] }, "reaction_10787471": { "compartment": "compartment_70616", "id": "reaction_10787471", "reactome": "R-SCE-8949580", "name": "F1Fo ATP synthase dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765816" ], "products": [ "species_10787469" ], "modifiers": [], "additional_components": [ "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W", "P24814", "YJR090C", "P00854", "Q0085", "P00830", "ATP2", "P30902", "YKL016C", "P61829", "OLI1", "P05626", "YPL078C", "P21306", "YPL271W", "Q12165", "YDL004W", "P09457", "YDR298C", "P38077", "YBR039W", "P07251", "ATP1", "Q12233", "YPR020W" ] }, "reaction_10761323": { "compartment": "compartment_70101", "id": "reaction_10761323", "reactome": "R-SCE-70475", "name": "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10761318", "catalyst" ] ], "additional_components": [ "P12709", "YBR196C" ] }, "reaction_10778180": { "compartment": "compartment_70101", "id": "reaction_10778180", "reactome": "R-SCE-5631885", "name": "PRDX1 overoxidizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29408", "species_10778172" ], "products": [ "species_29356", "species_10778177" ], "modifiers": [ [ "species_10778172", "catalyst" ] ], "additional_components": [ "P34760", "YML028W", "P34760", "YML028W", "P34760", "YML028W" ] }, "reaction_10762082": { "compartment": "compartment_70101", "id": "reaction_10762082", "reactome": "R-SCE-71682", "name": "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_111745" ], "products": [ "species_29366", "species_29450" ], "modifiers": [ [ "species_10762079", "catalyst" ] ], "additional_components": [ "P41921", "YPL091W", "species_113596" ] }, "reaction_10761172": { "compartment": "compartment_70101", "id": "reaction_10761172", "reactome": "R-SCE-70377", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_30537" ], "products": [ "species_70106", "species_29364", "species_31467" ], "modifiers": [ [ "species_10761169", "catalyst" ] ], "additional_components": [ "species_29366", "P11412", "YNL241C" ] }, "reaction_10771975": { "compartment": "compartment_20699", "id": "reaction_10771975", "reactome": "R-SCE-964737", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_915149" ], "products": [ "species_964740", "species_964752" ], "modifiers": [ [ "species_10771968", "catalyst" ] ], "additional_components": [ "YLR057W" ] }, "reaction_10777597": { "compartment": "compartment_70101", "id": "reaction_10777597", "reactome": "R-SCE-5358494", "name": "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777577", "species_71284" ], "products": [ "species_10777564", "species_353106" ], "modifiers": [ [ "species_10777594", "catalyst" ] ], "additional_components": [ "P32461", "YKL191W", "P40487", "YIL103W", "Q3E840", "YBL071W-A" ] }, "reaction_10769136": { "compartment": "compartment_70101", "id": "reaction_10769136", "reactome": "R-SCE-391266", "name": "Association of CCT/TriC with sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769132", "species_10769088" ], "products": [ "species_10769134" ], "modifiers": [], "additional_components": [ "P39079", "YDR188W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "YLR260W", "P39079", "YDR188W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "Q06147", "YLR260W" ] }, "reaction_10784720": { "compartment": "compartment_20699", "id": "reaction_10784720", "reactome": "R-SCE-6809015", "name": "NSF ATPase activity dissociates cis-SNARE at cis-Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10784715" ], "products": [ "species_10784697", "species_10784688", "species_10784699", "species_10784683", "species_29372", "species_10784703", "species_10784707" ], "modifiers": [ [ "species_10784715", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W", "P22804", "YIL004C", "P43682", "YKL006C-A", "YHL031C", "YLR026C", "YKL196C", "YLR078C", "YIL004C", "P25385", "YLR078C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W" ] }, "reaction_10776520": { "compartment": "compartment_12045", "id": "reaction_10776520", "reactome": "R-SCE-4419978", "name": "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4419987", "species_191362" ], "products": [ "species_4419982" ], "modifiers": [ [ "species_10776517", "catalyst" ] ], "additional_components": [ "Q12063", "YDL193W", "P35196", "YBR002C" ] }, "reaction_10765434": { "compartment": "compartment_70101", "id": "reaction_10765434", "reactome": "R-SCE-156930", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10765430" ], "products": [ "species_10765432" ], "modifiers": [], "additional_components": [ "P32324", "EFT2", "species_29438" ] }, "reaction_10774887": { "compartment": "compartment_7660", "id": "reaction_10774887", "reactome": "R-SCE-2997723", "name": "PIAS4 SUMOylates TP53BP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10774864" ], "products": [ "species_10774872", "species_10774805" ], "modifiers": [ [ "species_10774884", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDR217C", "Q12306", "YDR510W", "P14737", "YDR217C", "YDL064W", "Q04195", "YDR409W", "Q12216", "YOR156C" ] }, "reaction_10781067": { "compartment": "compartment_70101", "id": "reaction_10781067", "reactome": "R-SCE-5691431", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766135" ], "products": [ "species_10766133" ], "modifiers": [ [ "species_10760639", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YFR004W" ] }, "reaction_10786777": { "compartment": "compartment_70101", "id": "reaction_10786777", "reactome": "R-SCE-8870469", "name": "RGGT geranylgeranylates RAB proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786641", "species_1131164" ], "products": [ "species_10786772", "species_111294", "species_10786774" ], "modifiers": [ [ "species_10786641", "catalyst" ] ], "additional_components": [ "Q99260", "YLR262C", "species_1131164", "P32864", "YOR370C", "Q00618", "YJL031C", "P36017", "YOR089C", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P20133", "YPR176C", "P48559", "YNL304W", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "Q99260", "YLR262C", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P32864", "YOR370C", "P48559", "YNL304W", "P36017", "YOR089C", "species_1131164", "P20133", "YPR176C", "Q00618", "YJL031C", "Q99260", "YLR262C", "species_1131164", "P32864", "YOR370C", "Q00618", "YJL031C", "P36017", "YOR089C", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P20133", "YPR176C", "P48559", "YNL304W" ] }, "reaction_10787662": { "compartment": "compartment_17947", "id": "reaction_10787662", "reactome": "R-SCE-8953917", "name": "PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787654", "species_10787658" ], "products": [ "species_10787660" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "Q05568", "YDR265W", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "Q04370", "YMR026C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05568", "YDR265W" ] }, "reaction_10765525": { "compartment": "compartment_12045", "id": "reaction_10765525", "reactome": "R-SCE-162873", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855663", "species_449229" ], "products": [ "species_162872", "species_8855667" ], "modifiers": [ [ "species_10765522", "catalyst" ] ], "additional_components": [ "YBR004C" ] }, "reaction_10770358": { "compartment": "compartment_70101", "id": "reaction_10770358", "reactome": "R-SCE-446185", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449703" ], "products": [ "species_532204" ], "modifiers": [ [ "species_10770355", "catalyst" ] ], "additional_components": [ "YEL058W" ] }, "reaction_10768034": { "compartment": "compartment_70101", "id": "reaction_10768034", "reactome": "R-SCE-204662", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10767990", "species_29368" ], "products": [ "species_10768024", "species_29360", "species_29356" ], "modifiers": [ [ "species_10768031", "catalyst" ] ], "additional_components": [ "P19211", "YJR047C", "P23301", "YEL034W", "P19211", "YJR047C", "P23301", "YEL034W", "P47120", "YJR070C", "species_111793" ] }, "reaction_10787059": { "compartment": "compartment_7660", "id": "reaction_10787059", "reactome": "R-SCE-8932221", "name": "METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10775766" ], "products": [ "species_10787051", "species_77502" ], "modifiers": [ [ "species_10787056", "catalyst" ] ], "additional_components": [ "YLL024C", "YLL024C", "YNL024C" ] }, "reaction_10785932": { "compartment": "compartment_70101", "id": "reaction_10785932", "reactome": "R-SCE-8853529", "name": "OTULIN,USP5 cleaves UBB yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785930" ], "products": [ "species_10760584", "species_10760576", "species_10760568" ], "modifiers": [ [ "species_10780500", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YBR058C" ] }, "reaction_10776349": { "compartment": "compartment_7660", "id": "reaction_10776349", "reactome": "R-SCE-3900177", "name": "SUMOylation of DDX5 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776339" ], "products": [ "species_10774805", "species_10776347" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YNL112W", "YDL064W", "P24783", "YNL112W", "Q12306", "YDR510W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10772580": { "compartment": "compartment_70101", "id": "reaction_10772580", "reactome": "R-SCE-1022127", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772576" ], "products": [ "species_10772578" ], "modifiers": [], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "species_915149", "CHEBI:60627", "P05759", "RPS31", "species_964740", "CHEBI:60629", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "CHEBI:60628" ] }, "reaction_10770374": { "compartment": "compartment_17957", "id": "reaction_10770374", "reactome": "R-SCE-446189", "name": "Addition of a second glucose to the N-glycan precursor by ALG8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449649", "species_532542" ], "products": [ "species_449311", "species_449638" ], "modifiers": [ [ "species_10770371", "catalyst" ] ], "additional_components": [ "YOR067C" ] }, "reaction_10776364": { "compartment": "compartment_7660", "id": "reaction_10776364", "reactome": "R-SCE-3968362", "name": "SUMOylation of PIAS4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10774884" ], "products": [ "species_10776362", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "Q04195", "YDR409W", "Q12216", "YOR156C", "Q04195", "YDR409W", "Q12216", "YOR156C", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10781491": { "compartment": "compartment_6791047", "id": "reaction_10781491", "reactome": "R-SCE-5694425", "name": "NSF ATPase activity dissociates cis-SNARE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10781486" ], "products": [ "species_10781458", "species_10781451", "species_10769994", "species_10781444", "species_10781474", "species_10781482", "species_29372", "species_10781453" ], "modifiers": [ [ "species_10781486", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P22804", "YIL004C", "P22213", "YDR189W", "P36015", "YKL196C", "P32854", "YOR036W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W", "YDR189W", "YIL004C", "YBL050W", "P18759", "YBR080C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P32854", "YOR036W", "P36015", "YKL196C", "P22214", "YLR268W", "YLR078C", "P25385", "YLR078C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P22804", "YIL004C", "P22213", "YDR189W", "P36015", "YKL196C", "P32854", "YOR036W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W" ] }, "reaction_10776337": { "compartment": "compartment_7660", "id": "reaction_10776337", "reactome": "R-SCE-3900047", "name": "SUMOylation of DDX17 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776327", "species_10774813" ], "products": [ "species_10776335", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "YNL112W", "P50623", "YDL064W", "Q12306", "YDR510W", "P24783", "YNL112W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10785870": { "compartment": "compartment_70101", "id": "reaction_10785870", "reactome": "R-SCE-8852134", "name": "UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760634", "species_113592", "species_10772385" ], "products": [ "species_111294", "species_10785770" ], "modifiers": [ [ "species_10772385", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YKL210W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YKL210W" ] }, "reaction_10768010": { "compartment": "compartment_70101", "id": "reaction_10768010", "reactome": "R-SCE-204617", "name": "DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10767990", "species_204628" ], "products": [ "species_29360", "species_204635", "species_10768000" ], "modifiers": [ [ "species_10768007", "catalyst" ] ], "additional_components": [ "P19211", "YJR047C", "P23301", "YEL034W", "P19211", "YJR047C", "P23301", "YEL034W", "P38791", "YHR068W" ] }, "reaction_10770366": { "compartment": "compartment_17957", "id": "reaction_10770366", "reactome": "R-SCE-446188", "name": "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449298", "species_449229" ], "products": [ "species_449311", "species_449315" ], "modifiers": [ [ "species_10770363", "catalyst" ] ], "additional_components": [ "YBL082C" ] }, "reaction_10762154": { "compartment": "compartment_70101", "id": "reaction_10762154", "reactome": "R-SCE-71732", "name": "PPA1 hydrolyzes pyrophosphate to orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294", "species_29356" ], "products": [ "species_29372" ], "modifiers": [ [ "species_10762151", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P28239", "YMR267W", "P00817", "YBR011C" ] }, "reaction_10763035": { "compartment": "compartment_70101", "id": "reaction_10763035", "reactome": "R-SCE-72671", "name": "eIF5B:GTP is hydrolyzed and released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763029" ], "products": [ "species_10763031", "species_10763033", "species_29372" ], "modifiers": [], "additional_components": [ "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "P39730", "YAL035W", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B", "species_29420", "P39730", "YAL035W", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B" ] }, "reaction_10774923": { "compartment": "compartment_7660", "id": "reaction_10774923", "reactome": "R-SCE-3000434", "name": "PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774893", "species_10774813" ], "products": [ "species_10774805", "species_10774906" ], "modifiers": [ [ "species_10774920", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "Q12306", "YDR510W", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q04195", "YDR409W", "Q12216", "YOR156C" ] }, "reaction_10785859": { "compartment": "compartment_7660", "id": "reaction_10785859", "reactome": "R-SCE-8852130", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785838", "species_10785824" ], "products": [ "species_10785686", "species_10785857" ], "modifiers": [], "additional_components": [ "P52492", "YOR339C", "P15731", "YBR082C", "P15732", "YDR059C", "P06104", "YGL058W", "P14682", "YDR054C", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52492", "YOR339C", "P15731", "YBR082C", "P05759", "RPS31", "P15732", "YDR059C", "P06104", "YGL058W", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10787096": { "compartment": "compartment_70101", "id": "reaction_10787096", "reactome": "R-SCE-8932413", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10765400" ], "products": [ "species_71285", "species_10787088" ], "modifiers": [ [ "species_10787093", "catalyst" ] ], "additional_components": [ "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "YIL064W" ] }, "reaction_10776706": { "compartment": "compartment_7660", "id": "reaction_10776706", "reactome": "R-SCE-4641342", "name": "SUMOylation of TOP2A with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776696", "species_10774813" ], "products": [ "species_10776704", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "YNL088W", "P50623", "YDL064W", "Q12306", "YDR510W", "P06786", "YNL088W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10777327": { "compartment": "compartment_7660", "id": "reaction_10777327", "reactome": "R-SCE-5228523", "name": "RANBP2 SUMOylates MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774893", "species_10774813" ], "products": [ "species_10774805", "species_10774906" ], "modifiers": [ [ "species_10763942", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "Q12306", "YDR510W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P40066", "YER107C", "Q02455", "YKR095W", "P36161", "YKR082W", "P52891", "YDL116W", "P38181", "YBL079W", "P53011", "YGL100W", "P20676", "YOR098C", "P47054", "YJL039C", "Q02630", "YMR047C", "P40368", "YJL061W", "Q04491", "YLR208W", "Q05166", "YDL088C", "P46673", "YJR042W", "P48837", "YGR119C", "P34077", "YFR002W", "P14907", "YJL041W", "P52593", "YML103C", "P35729", "YKL057C", "P32500", "YML031W", "P41920", "YDR002W" ] }, "reaction_10776585": { "compartment": "compartment_7660", "id": "reaction_10776585", "reactome": "R-SCE-4570467", "name": "SUMOylation of NOP58 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776574" ], "products": [ "species_10774805", "species_10776583" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "Q12306", "YDR510W", "Q12499", "NOP58", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10784643": { "compartment": "compartment_6791047", "id": "reaction_10784643", "reactome": "R-SCE-6807877", "name": "ARFGAPs stimulate ARF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784546" ], "products": [ "species_10784367", "species_10784640", "species_10784463", "species_10784385" ], "modifiers": [ [ "species_10784546", "catalyst" ] ], "additional_components": [ "P32803", "YGL200C", "P25386", "YDL058W", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "P22804", "YIL004C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P36015", "YKL196C", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P32803", "YGL200C", "P25386", "YDL058W", "P53198", "YGL002W", "P22804", "YIL004C", "P39704", "YAL007C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P43621", "YFR051C", "P53600", "YPL010W", "P01123", "YFL038C", "P53622", "YDL145C", "Q12403", "YDL018C", "P40509", "YIL076W", "P36015", "YKL196C", "P32074", "YNL287W", "P41811", "YGL137W", "P32572", "YNL204C", "P38682", "YER122C", "P35197", "YDL226C", "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "P32803", "YGL200C", "P25386", "YDL058W", "Q06836", "YPR095C", "P39704", "YAL007C", "P19146", "YDL137W", "P41810", "YDR238C", "Q05359", "YAR002C-A", "P18414", "YBL040C", "P38819", "YHR110W", "P01123", "YFL038C", "P53622", "YDL145C", "P32572", "YNL204C", "P38682", "YER122C", "P47102", "YJR031C", "P53198", "YGL002W", "P11076", "YDL192W", "P22804", "YIL004C", "species_29438", "P54837", "YML012W", "Q12450", "YOR016C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P36015", "YKL196C", "Q12403", "YDL018C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P35197", "YDL226C" ] }, "reaction_10770382": { "compartment": "compartment_12045", "id": "reaction_10770382", "reactome": "R-SCE-446191", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449299", "species_162756" ], "products": [ "species_109402", "species_449222" ], "modifiers": [ [ "species_10770379", "catalyst" ] ], "additional_components": [ "YBR243C" ] }, "reaction_10776642": { "compartment": "compartment_7660", "id": "reaction_10776642", "reactome": "R-SCE-4615872", "name": "RANBP2 SUMOylates HDAC4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776632" ], "products": [ "species_10776640", "species_10774805" ], "modifiers": [ [ "species_10763942", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YNL021W", "Q12306", "YDR510W", "P53973", "YNL021W", "YDL064W", "P40066", "YER107C", "Q02455", "YKR095W", "P36161", "YKR082W", "P52891", "YDL116W", "P38181", "YBL079W", "P53011", "YGL100W", "P20676", "YOR098C", "P47054", "YJL039C", "Q02630", "YMR047C", "P40368", "YJL061W", "Q04491", "YLR208W", "Q05166", "YDL088C", "P46673", "YJR042W", "P48837", "YGR119C", "P34077", "YFR002W", "P14907", "YJL041W", "P52593", "YML103C", "P35729", "YKL057C", "P32500", "YML031W", "P41920", "YDR002W" ] }, "reaction_10765517": { "compartment": "compartment_70101", "id": "reaction_10765517", "reactome": "R-SCE-162857", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855657", "species_29356" ], "products": [ "species_29416", "species_8855661" ], "modifiers": [ [ "species_10765514", "catalyst" ] ], "additional_components": [ "YMR281W" ] }, "reaction_10770615": { "compartment": "compartment_5460", "id": "reaction_10770615", "reactome": "R-SCE-449937", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_159450" ], "products": [ "species_113548" ], "modifiers": [ [ "species_10770612", "catalyst" ], [ "species_109496", "catalyst" ] ], "additional_components": [ "P00817", "YBR011C" ] }, "reaction_10765380": { "compartment": "compartment_70101", "id": "reaction_10765380", "reactome": "R-SCE-156823", "name": "Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765355", "species_10765376" ], "products": [ "species_10765378" ], "modifiers": [], "additional_components": [ "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38760", "YHR015W", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "P04147", "YER165W", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P39684", "YFR023W", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38760", "YHR015W", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "P04147", "YER165W", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P39684", "YFR023W", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P26784", "RPL16A", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C" ] }, "reaction_10776408": { "compartment": "compartment_7660", "id": "reaction_10776408", "reactome": "R-SCE-4085350", "name": "SUMOylation of UBE2I with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10774805" ], "products": [ "species_10776406", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10787608": { "compartment": "compartment_70101", "id": "reaction_10787608", "reactome": "R-SCE-8952618", "name": "AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787593" ], "products": [ "species_10787605", "species_10787548" ], "modifiers": [ [ "species_10787593", "catalyst" ] ], "additional_components": [ "Q12395", "YLR128W", "P13365", "YAL040C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P24868", "YGR108W", "Q04511", "YML088W", "P20438", "YPL256C", "P32943", "YGR109C", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P52491", "YLR306W", "P36037", "YKL213C", "Q12347", "YLR097C", "Q03919", "YDR139C", "Q12395", "YLR128W", "P13365", "YAL040C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P24868", "YGR108W", "Q04511", "YML088W", "P20438", "YPL256C", "P32943", "YGR109C", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "Q03919", "YDR139C", "P36037", "YKL213C", "Q12347", "YLR097C", "YLR306W", "Q12395", "YLR128W", "P13365", "YAL040C", "Q08273", "YOL133W", "P52286", "YDR328C", "Q12018", "YDL132W", "P24868", "YGR108W", "Q04511", "YML088W", "P20438", "YPL256C", "P32943", "YGR109C", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "P52491", "YLR306W", "P36037", "YKL213C", "Q12347", "YLR097C", "Q03919", "YDR139C" ] }, "reaction_10773656": { "compartment": "compartment_70101", "id": "reaction_10773656", "reactome": "R-SCE-1799332", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773652", "species_10773650" ], "products": [ "species_10773654" ], "modifiers": [], "additional_components": [ "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B", "P38687", "YPL243W", "P32342", "YKL122C", "P38688", "YPL210C", "P29478", "YML105C", "P38985", "YDL092W", "P20424", "YPR088C", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29478", "YML105C", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P20424", "YPR088C", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P38687", "YPL243W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P32342", "YKL122C", "P38688", "YPL210C", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "P38985", "YDL092W", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B" ] }, "reaction_10777561": { "compartment": "compartment_70101", "id": "reaction_10777561", "reactome": "R-SCE-5358475", "name": "DPH6 ligates ammonium to diphthine-EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_31633", "species_10777553" ], "products": [ "species_10765430", "species_111294", "species_76577" ], "modifiers": [ [ "species_10777558", "catalyst" ] ], "additional_components": [ "YLR143W" ] }, "reaction_10786576": { "compartment": "compartment_70101", "id": "reaction_10786576", "reactome": "R-SCE-8870465", "name": "RGGT binds the RAB-binding subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786568", "species_10784093", "species_1131164" ], "products": [ "species_10786574" ], "modifiers": [], "additional_components": [ "P20133", "YPR176C", "Q00618", "YJL031C", "YOR370C", "species_1131164", "P32864", "YOR370C", "P20133", "YPR176C", "Q00618", "YJL031C" ] }, "reaction_10775215": { "compartment": "compartment_7660", "id": "reaction_10775215", "reactome": "R-SCE-3232162", "name": "PIAS3 SUMOylates MITF with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10775197" ], "products": [ "species_10774805", "species_10775206" ], "modifiers": [ [ "species_10775212", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YBL103C", "YDL064W", "P38165", "YBL103C", "Q12306", "YDR510W", "Q04195", "YDR409W", "Q12216", "YOR156C" ] }, "reaction_10762699": { "compartment": "compartment_70101", "id": "reaction_10762699", "reactome": "R-SCE-72663", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10762638" ], "products": [ "species_10762640" ], "modifiers": [], "additional_components": [ "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438" ] }, "reaction_10787672": { "compartment": "compartment_17947", "id": "reaction_10787672", "reactome": "R-SCE-8953946", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787660" ], "products": [ "species_10772640", "species_10787669" ], "modifiers": [ [ "species_10787660", "catalyst" ] ], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "Q04370", "YMR026C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05568", "YDR265W", "P15731", "YBR082C", "P15732", "YDR059C", "P35056", "phospho-PEX5", "P53112", "PEX14", "P05759", "RPS31", "P80667", "PEX13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q04370", "YMR026C", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "Q04370", "YMR026C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05568", "YDR265W" ] }, "reaction_10770406": { "compartment": "compartment_12045", "id": "reaction_10770406", "reactome": "R-SCE-446200", "name": "DOLPP1 dephosphorylates DOLDP to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449744", "species_29356" ], "products": [ "species_449299", "species_29372" ], "modifiers": [ [ "species_10770403", "catalyst" ] ], "additional_components": [ "YGR036C" ] }, "reaction_10762732": { "compartment": "compartment_70101", "id": "reaction_10762732", "reactome": "R-SCE-72670", "name": "Formation of eIF2:GDP:eIF2B intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762728", "species_10762689" ], "products": [ "species_10762730" ], "modifiers": [], "additional_components": [ "P09032", "YOR260W", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P32501", "YDR211W", "species_29420", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "P09032", "YOR260W", "species_29420", "P32481", "GCD11", "P09064", "SUI3", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P20459", "phospho-SUI2", "P32501", "YDR211W" ] }, "reaction_10776691": { "compartment": "compartment_7660", "id": "reaction_10776691", "reactome": "R-SCE-4616015", "name": "SUMOylation of HDAC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776117", "species_10774813" ], "products": [ "species_10776689", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "YPR068C", "P50623", "YDL064W", "Q12306", "YDR510W", "Q12306", "YDR510W", "Q12214", "YPR068C", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10785332": { "compartment": "compartment_6791047", "id": "reaction_10785332", "reactome": "R-SCE-6814831", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781520", "species_10785328" ], "products": [ "species_10785330" ], "modifiers": [], "additional_components": [ "P01123", "YFL038C", "species_29438", "YFL027C", "P01123", "YFL038C", "species_29438", "P43570", "YFL027C" ] }, "reaction_10770593": { "compartment": "compartment_70101", "id": "reaction_10770593", "reactome": "R-SCE-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29512" ], "products": [ "species_29404", "species_449701" ], "modifiers": [ [ "species_10770590", "catalyst" ] ], "additional_components": [ "P14742", "YKL104C", "P0CF18", "YMR085W" ] }, "reaction_10776528": { "compartment": "compartment_12045", "id": "reaction_10776528", "reactome": "R-SCE-4419979", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_4419981" ], "products": [ "species_29366", "species_449221" ], "modifiers": [ [ "species_10776525", "catalyst" ] ], "additional_components": [ "YIL049W" ] }, "reaction_10785861": { "compartment": "compartment_7660", "id": "reaction_10785861", "reactome": "R-SCE-8852131", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10785822", "species_10760537" ], "products": [ "species_113541", "species_10785824" ], "modifiers": [], "additional_components": [ "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10763043": { "compartment": "compartment_70101", "id": "reaction_10763043", "reactome": "R-SCE-72691", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763041", "species_10762642" ], "products": [ "species_10762644" ], "modifiers": [], "additional_components": [ "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P40217", "YMR146C", "P0CX32", "RPS24B", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C" ] }, "reaction_10776600": { "compartment": "compartment_7660", "id": "reaction_10776600", "reactome": "R-SCE-4570493", "name": "RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776590", "species_10774813" ], "products": [ "species_10776598", "species_10774805" ], "modifiers": [ [ "species_10763942", "catalyst" ] ], "additional_components": [ "YPL190C", "P50623", "YDL064W", "Q12306", "YDR510W", "P38996", "YPL190C", "Q12306", "YDR510W", "YDL064W", "P40066", "YER107C", "Q02455", "YKR095W", "P36161", "YKR082W", "P52891", "YDL116W", "P38181", "YBL079W", "P53011", "YGL100W", "P20676", "YOR098C", "P47054", "YJL039C", "Q02630", "YMR047C", "P40368", "YJL061W", "Q04491", "YLR208W", "Q05166", "YDL088C", "P46673", "YJR042W", "P48837", "YGR119C", "P34077", "YFR002W", "P14907", "YJL041W", "P52593", "YML103C", "P35729", "YKL057C", "P32500", "YML031W", "P41920", "YDR002W" ] }, "reaction_10770224": { "compartment": "compartment_1462052", "id": "reaction_10770224", "reactome": "R-SCE-437085", "name": "ZnT5 transports zinc into secretory granules in pancreatic beta cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10770221", "catalyst" ] ], "additional_components": [ "YDR205W" ] }, "reaction_10770603": { "compartment": "compartment_70101", "id": "reaction_10770603", "reactome": "R-SCE-449734", "name": "Acetylation of glucosamine 6-phosphate to GlcNAc6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449701", "species_76183" ], "products": [ "species_76194", "species_449703" ], "modifiers": [ [ "species_10770600", "catalyst" ] ], "additional_components": [ "P43577", "YFL017C" ] }, "reaction_10786570": { "compartment": "compartment_70101", "id": "reaction_10786570", "reactome": "R-SCE-8870461", "name": "RABGGTA and RABGGTB bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786564", "species_10786566" ], "products": [ "species_10786568" ], "modifiers": [], "additional_components": [ "YJL031C", "YPR176C", "P20133", "YPR176C", "Q00618", "YJL031C" ] }, "reaction_10762701": { "compartment": "compartment_70101", "id": "reaction_10762701", "reactome": "R-SCE-72669", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762640", "species_72393" ], "products": [ "species_10762642" ], "modifiers": [ [ "species_29438", "catalyst" ] ], "additional_components": [ "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438" ] }, "reaction_10781400": { "compartment": "compartment_13959", "id": "reaction_10781400", "reactome": "R-SCE-5694409", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10781393" ], "products": [ "species_10781397", "species_29420" ], "modifiers": [ [ "species_10781393", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "species_29420", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P40482", "YIL109C", "P01123", "YFL038C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C", "P25385", "YLR078C", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "species_29438", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P01123", "YFL038C", "P40482", "YIL109C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C", "P25385", "YLR078C", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "species_29420", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P40482", "YIL109C", "P01123", "YFL038C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C" ] }, "reaction_10776398": { "compartment": "compartment_7660", "id": "reaction_10776398", "reactome": "R-SCE-3968414", "name": "UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776376" ], "products": [ "species_10774805", "species_10776393" ], "modifiers": [ [ "species_10776395", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "P25364", "YCR065W", "P40466", "YIL131C", "YDL064W", "Q12306", "YDR510W", "P25364", "YCR065W", "P40466", "YIL131C", "Q04195", "YDR409W", "Q12216", "YOR156C", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10770449": { "compartment": "compartment_12045", "id": "reaction_10770449", "reactome": "R-SCE-446214", "name": "Synthesis of dolichyl-phosphate-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_449299" ], "products": [ "species_110096", "species_532214" ], "modifiers": [ [ "species_10770446", "catalyst" ] ], "additional_components": [ "YPL227C" ] }, "reaction_10785688": { "compartment": "compartment_7660", "id": "reaction_10785688", "reactome": "R-SCE-8852128", "name": "UBA1 adenylates ubiquitin in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10785583", "species_10760537" ], "products": [ "species_10785686", "species_113541" ], "modifiers": [], "additional_components": [ "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10771977": { "compartment": "compartment_20699", "id": "reaction_10771977", "reactome": "R-SCE-964825", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964831" ], "products": [ "species_964740", "species_964752" ], "modifiers": [ [ "species_10771968", "catalyst" ] ], "additional_components": [ "CHEBI:60627", "CHEBI:60629", "CHEBI:60628", "YLR057W" ] }, "reaction_10774770": { "compartment": "compartment_7660", "id": "reaction_10774770", "reactome": "R-SCE-2990840", "name": "SENP1,2,5 proteolytically process SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774758" ], "products": [ "species_10774743" ], "modifiers": [ [ "species_10774763", "catalyst" ] ], "additional_components": [ "YDR510W", "YDR510W", "YPL020C" ] }, "reaction_10776472": { "compartment": "compartment_7660", "id": "reaction_10776472", "reactome": "R-SCE-4090284", "name": "SUMOylation of HIPK2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776462" ], "products": [ "species_10776470", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YJL141C", "P14680", "YJL141C", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10782019": { "compartment": "compartment_12045", "id": "reaction_10782019", "reactome": "R-SCE-6788650", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788753", "species_71284" ], "products": [ "species_6788758", "species_71285" ], "modifiers": [ [ "species_10782016", "catalyst" ] ], "additional_components": [ "species_158417", "P32584", "YDR410C" ] }, "reaction_10785820": { "compartment": "compartment_70101", "id": "reaction_10785820", "reactome": "R-SCE-8852129", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785690", "species_10785768" ], "products": [ "species_10785818", "species_10785770" ], "modifiers": [], "additional_components": [ "P52492", "YOR339C", "P15731", "YBR082C", "P15732", "YDR059C", "P14682", "YDR054C", "P28263", "YEL012W", "Q02159", "YMR022W", "P21734", "YDR177W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52492", "YOR339C", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P14682", "YDR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P28263", "YEL012W", "Q02159", "YMR022W", "P21734", "YDR177W", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10770457": { "compartment": "compartment_17957", "id": "reaction_10770457", "reactome": "R-SCE-446215", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449315", "species_449229" ], "products": [ "species_449311", "species_449312" ], "modifiers": [ [ "species_10770454", "catalyst" ] ], "additional_components": [ "YNL219C" ] }, "reaction_10787521": { "compartment": "compartment_70101", "id": "reaction_10787521", "reactome": "R-SCE-8951644", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781029" ], "products": [ "species_10781027", "species_10780910" ], "modifiers": [], "additional_components": [ "P35127", "YJR099W", "Q03919", "YDR139C", "YDR139C", "YJR099W" ] }, "reaction_10770459": { "compartment": "compartment_17957", "id": "reaction_10770459", "reactome": "R-SCE-446216", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449365" ], "products": [ "species_449311", "species_449371" ], "modifiers": [ [ "species_10770454", "catalyst" ] ], "additional_components": [ "YNL219C" ] }, "reaction_10765384": { "compartment": "compartment_70101", "id": "reaction_10765384", "reactome": "R-SCE-156826", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763018" ], "products": [ "species_10765382", "species_10762778" ], "modifiers": [], "additional_components": [ "P05748", "RPL15A", "P10622", "YDL130W", "P0CX83", "RPL19B", "P26321", "RPL5", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX23", "RPL20A", "P0CX54", "RPL12B", "P51401", "RPL9B", "P14126", "RPL3", "P0CX46", "RPL2B", "P0CH08", "RPL40A", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0CX42", "RPL23B", "P53221", "RPL26B", "P10664", "RPL4A", "P05740", "RPL17A", "P0CX27", "RPL42A", "P0CX44", "RPL1B", "P0CX28", "RPL42B", "P54780", "RPL15B", "P05744", "RPL33A", "P05759", "RPS31", "P02406", "RPL28", "P0CH09", "RPL40B", "P0C0W9", "RPL11A", "P04449", "RPL24A", "P0CX50", "RPL18B", "P41805", "RPL10", "P38061", "RPL32", "P0CX49", "RPL18A", "P0CX45", "RPL2A", "P14120", "RPL30", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P0CX43", "RPL1A", "P49166", "RPL37A", "P0CX53", "RPL12A", "P05749", "RPL22A", "P0CX82", "RPL19A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q3E757", "RPL11B", "P02400", "RPP2B", "P49626", "RPL4B", "P51402", "RPL37B", "P05743", "RPL26A", "P0C2H9", "RPL31B", "P05739", "RPL6B", "P05748", "RPL15A", "P10622", "YDL130W", "P0CX83", "RPL19B", "P26321", "RPL5", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX23", "RPL20A", "P0CX54", "RPL12B", "P51401", "RPL9B", "P14126", "RPL3", "P0CX46", "RPL2B", "P0CH08", "RPL40A", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0CX42", "RPL23B", "P53221", "RPL26B", "P10664", "RPL4A", "P05740", "RPL17A", "P0CX27", "RPL42A", "P0CX44", "RPL1B", "P0CX28", "RPL42B", "P54780", "RPL15B", "P05744", "RPL33A", "P05759", "RPS31", "P02406", "RPL28", "P0CH09", "RPL40B", "P0C0W9", "RPL11A", "P04449", "RPL24A", "P0CX50", "RPL18B", "P41805", "RPL10", "P38061", "RPL32", "P0CX49", "RPL18A", "P0CX45", "RPL2A", "P14120", "RPL30", "P05737", "RPL7A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P0CX43", "RPL1A", "P49166", "RPL37A", "P0CX53", "RPL12A", "P05749", "RPL22A", "P0CX82", "RPL19A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q3E757", "RPL11B", "P02400", "RPP2B", "P49626", "RPL4B", "P51402", "RPL37B", "P05743", "RPL26A", "P0C2H9", "RPL31B", "P05739", "RPL6B" ] }, "reaction_10784442": { "compartment": "compartment_6791047", "id": "reaction_10784442", "reactome": "R-SCE-6807872", "name": "Active ARF recruits coatomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784438", "species_10784393" ], "products": [ "species_10784440" ], "modifiers": [], "additional_components": [ "P43621", "YFR051C", "P53600", "YPL010W", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W", "P41810", "YDR238C", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P41810", "YDR238C", "P43621", "YFR051C", "P53600", "YPL010W", "P39993", "YEL022W", "P01123", "YFL038C", "P53622", "YDL145C", "P40509", "YIL076W", "P32074", "YNL287W", "P41811", "YGL137W" ] }, "reaction_10781493": { "compartment": "compartment_13959", "id": "reaction_10781493", "reactome": "R-SCE-5694439", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781391", "species_10781345", "species_10767942" ], "products": [ "species_10781393" ], "modifiers": [], "additional_components": [ "P38334", "YBR254C", "Q03630", "YML077W", "Q03784", "YDR246W", "P36149", "YKR068C", "Q04183", "YDR407C", "Q03337", "YDR472W", "Q03660", "YMR218C", "Q99394", "YOR115C", "species_29420", "P01123", "YFL038C", "P25385", "YLR078C", "Q01590", "YLR026C", "Q04491", "YLR208W", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "Q12204", "YOR022C", "P36015", "YKL196C", "P15303", "YPR181C", "P22214", "YLR268W", "P38968", "YDL195W", "P25385", "YLR078C", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "species_29420", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P40482", "YIL109C", "P01123", "YFL038C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C" ] }, "reaction_10763039": { "compartment": "compartment_70101", "id": "reaction_10763039", "reactome": "R-SCE-72673", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762624", "species_10763020" ], "products": [ "species_10762624", "species_10762573", "species_10763018" ], "modifiers": [], "additional_components": [ "YMR260C", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B", "YMR260C", "P0CX52", "RPS16B", "P35997", "RPS27A", "Q08745", "RPS10A", "P46784", "RPS10B", "P25443", "RPS2", "P06367", "RPS14A", "P0CX55", "RPS18A", "P0CX32", "RPS24B", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX35", "RPS4A", "P23248", "RPS1B", "P0CH08", "RPL40A", "P0CX47", "RPS11A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "P0CX37", "RPS6A", "P0CX56", "RPS18B", "P38711", "RPS27B", "P26786", "RPS7A", "P0CX30", "RPS23B", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P07281", "RPS19B", "P05759", "RPS31", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P05748", "RPL15A", "P10622", "YDL130W", "P0CX83", "RPL19B", "P26321", "RPL5", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX23", "RPL20A", "P0CX54", "RPL12B", "P51401", "RPL9B", "P14126", "RPL3", "P0CX46", "RPL2B", "P0CH08", "RPL40A", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0CX42", "RPL23B", "P53221", "RPL26B", "P10664", "RPL4A", "P05740", "RPL17A", "P0CX27", "RPL42A", "P0CX44", "RPL1B", "P0CX28", "RPL42B", "P54780", "RPL15B", "P05744", "RPL33A", "P05759", "RPS31", "P02406", "RPL28", "P0CH09", "RPL40B", "P0C0W9", "RPL11A", "P04449", "RPL24A", "P0CX50", "RPL18B", "P41805", "RPL10", "P38061", "RPL32", "P0CX49", "RPL18A", "P0CX45", "RPL2A", "P14120", "RPL30", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P0CX43", "RPL1A", "P49166", "RPL37A", "P0CX53", "RPL12A", "P05749", "RPL22A", "P0CX82", "RPL19A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q3E757", "RPL11B", "P02400", "RPP2B", "P49626", "RPL4B", "P51402", "RPL37B", "P05743", "RPL26A", "P0C2H9", "RPL31B", "P05739", "RPL6B" ] }, "reaction_10781528": { "compartment": "compartment_6791047", "id": "reaction_10781528", "reactome": "R-SCE-5694441", "name": "CSNK1D phosphorylates SEC23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10781508" ], "products": [ "species_29370", "species_10781391", "species_10781520", "species_10781512", "species_10781437", "species_10767811", "species_10781514" ], "modifiers": [ [ "species_10781525", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "P25386", "YDL058W", "P38810", "YHR098C", "Q03784", "YDR246W", "P36149", "YKR068C", "species_29438", "Q03660", "YMR218C", "P22214", "YLR268W", "P38968", "YDL195W", "P38334", "YBR254C", "Q01590", "YLR026C", "Q04491", "YLR208W", "Q03630", "YML077W", "P53953", "YNL049C", "P01123", "YFL038C", "P40482", "YIL109C", "Q12204", "YOR022C", "P36015", "YKL196C", "Q04183", "YDR407C", "Q03337", "YDR472W", "P15303", "YPR181C", "Q99394", "YOR115C", "Q04410", "YDR517W", "P38334", "YBR254C", "Q03630", "YML077W", "Q03784", "YDR246W", "P36149", "YKR068C", "Q04183", "YDR407C", "Q03337", "YDR472W", "Q03660", "YMR218C", "Q99394", "YOR115C", "P01123", "YFL038C", "species_29438", "YPR181C", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "Q04491", "YLR208W", "Q12204", "YOR022C", "P38968", "YDL195W", "P25385", "YLR078C", "Q01590", "YLR026C", "P25386", "YDL058W", "P38810", "YHR098C", "P36015", "YKL196C", "P15303", "YPR181C", "P22214", "YLR268W", "Q04410", "YDR517W", "YPL204W" ] }, "reaction_10765493": { "compartment": "compartment_12045", "id": "reaction_10765493", "reactome": "R-SCE-162797", "name": "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855656", "species_449229" ], "products": [ "species_8855664" ], "modifiers": [ [ "species_10765490", "catalyst" ] ], "additional_components": [ "YOR149C" ] }, "reaction_10770398": { "compartment": "compartment_17957", "id": "reaction_10770398", "reactome": "R-SCE-446198", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449312", "species_449229" ], "products": [ "species_449311", "species_449365" ], "modifiers": [ [ "species_10770395", "catalyst" ] ], "additional_components": [ "YNR030W" ] }, "reaction_10765509": { "compartment": "compartment_12045", "id": "reaction_10765509", "reactome": "R-SCE-162821", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855667", "species_449229" ], "products": [ "species_8855656", "species_162872" ], "modifiers": [ [ "species_10765506", "catalyst" ] ], "additional_components": [ "YGL142C" ] }, "reaction_10785872": { "compartment": "compartment_7660", "id": "reaction_10785872", "reactome": "R-SCE-8852136", "name": "UBA1 conjugates ubiquitin to UBA1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785686" ], "products": [ "species_10785822", "species_164121" ], "modifiers": [], "additional_components": [ "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10781420": { "compartment": "compartment_12045", "id": "reaction_10781420", "reactome": "R-SCE-5694415", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767888", "species_10781416", "species_10767816" ], "products": [ "species_10781418" ], "modifiers": [], "additional_components": [ "YPR181C", "P53953", "YNL049C", "P40482", "YIL109C", "YLR268W", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "P22214", "YLR268W" ] }, "reaction_10787561": { "compartment": "compartment_70101", "id": "reaction_10787561", "reactome": "R-SCE-8951661", "name": "Transfer of NEDD8 to AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787550" ], "products": [ "species_10787558", "species_10787538" ], "modifiers": [ [ "species_10787550", "catalyst" ] ], "additional_components": [ "Q12059", "YPL003W", "Q99344", "YPR066W", "P52491", "YLR306W", "Q03919", "YDR139C", "P52491", "YLR306W", "Q03919", "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "P52491", "YLR306W", "Q03919", "YDR139C" ] }, "reaction_10785864": { "compartment": "compartment_70101", "id": "reaction_10785864", "reactome": "R-SCE-8852132", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785692", "species_113592", "species_10760634" ], "products": [ "species_111294", "species_10785768" ], "modifiers": [ [ "species_10785692", "catalyst" ] ], "additional_components": [ "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10762691": { "compartment": "compartment_70101", "id": "reaction_10762691", "reactome": "R-SCE-72621", "name": "Ribosomal scanning ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762680", "species_113592" ], "products": [ "species_29370", "species_10762680", "species_29372" ], "modifiers": [ [ "species_72617", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C" ] }, "reaction_10787567": { "compartment": "compartment_70101", "id": "reaction_10787567", "reactome": "R-SCE-8951751", "name": "Doubly neddylated UBA3:NAE1 binds AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787543", "species_10787548" ], "products": [ "species_10787550" ], "modifiers": [], "additional_components": [ "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C", "YLR306W", "Q12059", "YPL003W", "Q99344", "YPR066W", "P52491", "YLR306W", "Q03919", "YDR139C" ] }, "reaction_10786643": { "compartment": "compartment_70101", "id": "reaction_10786643", "reactome": "R-SCE-8870466", "name": "RGGT:CHM binds RABs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786574", "species_10786639" ], "products": [ "species_10786641" ], "modifiers": [], "additional_components": [ "species_1131164", "P32864", "YOR370C", "P20133", "YPR176C", "Q00618", "YJL031C", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "Q99260", "YLR262C", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P48559", "YNL304W", "P36017", "YOR089C", "Q99260", "YLR262C", "species_1131164", "P32864", "YOR370C", "Q00618", "YJL031C", "P36017", "YOR089C", "species_29420", "P07560", "YFL005W", "P36019", "YNL093W", "P01123", "YFL038C", "P32939", "YML001W", "P51996", "YGL210W", "P38555", "YER031C", "P20133", "YPR176C", "P48559", "YNL304W" ] }, "reaction_10776610": { "compartment": "compartment_7660", "id": "reaction_10776610", "reactome": "R-SCE-4570496", "name": "SUMOylation of Histone H4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10763701" ], "products": [ "species_10774805", "species_10776608" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YBR009C", "YDL064W", "P02309", "YBR009C", "Q12306", "YDR510W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10771137": { "compartment": "compartment_70101", "id": "reaction_10771137", "reactome": "R-SCE-532549", "name": "MPI isomerises Fru6P to Man6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_532562" ], "modifiers": [ [ "species_10771134", "catalyst" ] ], "additional_components": [ "YER003C" ] }, "reaction_10784375": { "compartment": "compartment_6791047", "id": "reaction_10784375", "reactome": "R-SCE-6807864", "name": "RAB1:GTP recruits GBF1 to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781520", "species_10784367", "species_10784371" ], "products": [ "species_10784373" ], "modifiers": [], "additional_components": [ "P01123", "YFL038C", "species_29438", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P25386", "YDL058W", "P47102", "YJR031C", "P25386", "YDL058W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "species_29438" ] }, "reaction_10785905": { "compartment": "compartment_70101", "id": "reaction_10785905", "reactome": "R-SCE-8853503", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760568" ], "products": [ "species_10762487", "species_10760568" ], "modifiers": [ [ "species_10785902", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P50101", "YMR304W", "P35127", "YJR099W" ] }, "reaction_10775006": { "compartment": "compartment_7660", "id": "reaction_10775006", "reactome": "R-SCE-3108212", "name": "SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10774426" ], "products": [ "species_10774805", "species_10774972" ], "modifiers": [ [ "species_10775003", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "P32908", "YFL008W", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "YDL064W", "P32908", "YFL008W", "Q12306", "YDR510W", "Q12158", "YDL003W", "P47037", "YJL074C", "P40541", "YIL026C", "P43124", "YDL105W", "Q12749", "YLR383W", "Q05541", "YDR288W", "P38632", "YEL019C", "Q07913", "YLR007W", "Q08204", "YOL034W" ] }, "reaction_10781488": { "compartment": "compartment_6791047", "id": "reaction_10781488", "reactome": "R-SCE-5694423", "name": "NSF and SNAPs bind cis-SNARE complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781484", "species_10769994", "species_10781444" ], "products": [ "species_10781486" ], "modifiers": [], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P22804", "YIL004C", "P22213", "YDR189W", "P36015", "YKL196C", "P32854", "YOR036W", "P22214", "YLR268W", "YBL050W", "P18759", "YBR080C", "P25385", "YLR078C", "Q01590", "YLR026C", "Q12241", "YOR106W", "P22804", "YIL004C", "P22213", "YDR189W", "P36015", "YKL196C", "P32854", "YOR036W", "P18759", "YBR080C", "P32602", "YBL050W", "P22214", "YLR268W" ] }, "reaction_10765501": { "compartment": "compartment_12045", "id": "reaction_10765501", "reactome": "R-SCE-162798", "name": "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_8855659" ], "products": [ "species_8855663", "species_1500596" ], "modifiers": [ [ "species_10765498", "catalyst" ] ], "additional_components": [ "YKL165C" ] }, "reaction_10781414": { "compartment": "compartment_12045", "id": "reaction_10781414", "reactome": "R-SCE-5694413", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767882", "species_10767884", "species_10767888" ], "products": [ "species_10767890" ], "modifiers": [], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "YHR098C", "YPR181C", "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P15303", "YPR181C" ] }, "reaction_10787077": { "compartment": "compartment_70101", "id": "reaction_10787077", "reactome": "R-SCE-8932276", "name": "VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10777462" ], "products": [ "species_10787065", "species_71285" ], "modifiers": [ [ "species_10787074", "catalyst" ] ], "additional_components": [ "YDL126C", "YDL126C", "Q12367", "YLR137W", "P53970", "YNL024C" ] }, "reaction_10763037": { "compartment": "compartment_70101", "id": "reaction_10763037", "reactome": "R-SCE-72672", "name": "The 60S subunit joins the translation initiation complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762687", "species_10763027", "species_10763018" ], "products": [ "species_10763029" ], "modifiers": [], "additional_components": [ "P0CX52", "RPS16B", "P35997", "RPS27A", "Q08745", "RPS10A", "P46784", "RPS10B", "P25443", "RPS2", "P06367", "RPS14A", "P0CX55", "RPS18A", "P0CX32", "RPS24B", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX35", "RPS4A", "P23248", "RPS1B", "P0CH08", "RPL40A", "P0CX47", "RPS11A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P05756", "RPS13", "P0CX37", "RPS6A", "P0CX56", "RPS18B", "P38711", "RPS27B", "P26786", "RPS7A", "P0CX30", "RPS23B", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P07281", "RPS19B", "P05759", "RPS31", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P14127", "RPS17B", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "species_29438", "P39730", "YAL035W", "P05748", "RPL15A", "P10622", "YDL130W", "P0CX83", "RPL19B", "P26321", "RPL5", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX23", "RPL20A", "P0CX54", "RPL12B", "P51401", "RPL9B", "P14126", "RPL3", "P0CX46", "RPL2B", "P0CH08", "RPL40A", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0CX42", "RPL23B", "P53221", "RPL26B", "P10664", "RPL4A", "P05740", "RPL17A", "P0CX27", "RPL42A", "P0CX44", "RPL1B", "P0CX28", "RPL42B", "P54780", "RPL15B", "P05744", "RPL33A", "P05759", "RPS31", "P02406", "RPL28", "P0CH09", "RPL40B", "P0C0W9", "RPL11A", "P04449", "RPL24A", "P0CX50", "RPL18B", "P41805", "RPL10", "P38061", "RPL32", "P0CX49", "RPL18A", "P0CX45", "RPL2A", "P14120", "RPL30", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P0CX43", "RPL1A", "P49166", "RPL37A", "P0CX53", "RPL12A", "P05749", "RPL22A", "P0CX82", "RPL19A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q3E757", "RPL11B", "P02400", "RPP2B", "P49626", "RPL4B", "P51402", "RPL37B", "P05743", "RPL26A", "P0C2H9", "RPL31B", "P05739", "RPL6B", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P38061", "RPL32", "P14120", "RPL30", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "P39730", "YAL035W", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B" ] }, "reaction_10784389": { "compartment": "compartment_6791047", "id": "reaction_10784389", "reactome": "R-SCE-6807866", "name": "GBF1 recruits ARF:GDP to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784373", "species_10784385" ], "products": [ "species_10784387" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P25386", "YDL058W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "species_29438", "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "species_29420", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438" ] }, "reaction_10770434": { "compartment": "compartment_70101", "id": "reaction_10770434", "reactome": "R-SCE-446204", "name": "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532204", "species_29494" ], "products": [ "species_111294", "species_162756" ], "modifiers": [ [ "species_10770431", "catalyst" ] ], "additional_components": [ "P43123", "YDL103C" ] }, "reaction_10776442": { "compartment": "compartment_7660", "id": "reaction_10776442", "reactome": "R-SCE-4086083", "name": "SUMOylation of ING2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776424" ], "products": [ "species_10776440", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "Q08465", "YOR064C", "P50947", "YNL097C", "P38806", "YHR090C", "Q08465", "YOR064C", "Q12306", "YDR510W", "P50947", "YNL097C", "P38806", "YHR090C", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10787541": { "compartment": "compartment_70101", "id": "reaction_10787541", "reactome": "R-SCE-8951648", "name": "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781027", "species_113592", "species_10787528" ], "products": [ "species_111294", "species_76577", "species_10787538" ], "modifiers": [ [ "species_10787528", "catalyst" ] ], "additional_components": [ "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W" ] }, "reaction_10776669": { "compartment": "compartment_7660", "id": "reaction_10776669", "reactome": "R-SCE-4615889", "name": "SUMOylation of HDAC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772638", "species_10774813" ], "products": [ "species_10776667", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "YPR068C", "P50623", "YDL064W", "Q12306", "YDR510W", "Q12306", "YDR510W", "Q12214", "YPR068C", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10770467": { "compartment": "compartment_12045", "id": "reaction_10770467", "reactome": "R-SCE-446218", "name": "Addition of the first mannose to the N-glycan precursor by ALG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449293" ], "products": [ "species_449283", "species_29420" ], "modifiers": [ [ "species_10770464", "catalyst" ] ], "additional_components": [ "YBR110W" ] }, "reaction_10770441": { "compartment": "compartment_12045", "id": "reaction_10770441", "reactome": "R-SCE-446208", "name": "Addition of a second mannose to the N-glycan precursor by ALG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449283" ], "products": [ "species_449737", "species_29420" ], "modifiers": [ [ "species_10770438", "catalyst" ] ], "additional_components": [] }, "reaction_10784396": { "compartment": "compartment_6791047", "id": "reaction_10784396", "reactome": "R-SCE-6807868", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784387", "species_113592" ], "products": [ "species_29370", "species_10784393" ], "modifiers": [ [ "species_10784387", "catalyst" ] ], "additional_components": [ "species_29420", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438", "species_29420", "P47102", "YJR031C", "P25386", "YDL058W", "P11076", "YDL192W", "P39993", "YEL022W", "P01123", "YFL038C", "Q06836", "YPR095C", "P19146", "YDL137W", "species_29438" ] }, "reaction_10776681": { "compartment": "compartment_7660", "id": "reaction_10776681", "reactome": "R-SCE-4615910", "name": "SUMOylation of PCNA with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10760932" ], "products": [ "species_10774805", "species_10776679" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YBR088C", "YDL064W", "Q12306", "YDR510W", "P15873", "YBR088C", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10785219": { "compartment": "compartment_70101", "id": "reaction_10785219", "reactome": "R-SCE-6814119", "name": "TRiC/CCT binds unfolded G-protein beta subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785211", "species_10769132" ], "products": [ "species_10785217" ], "modifiers": [], "additional_components": [ "YOR212W", "P39079", "YDR188W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W" ] }, "reaction_10767954": { "compartment": "compartment_70101", "id": "reaction_10767954", "reactome": "R-SCE-203977", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10767946" ], "products": [ "species_10767870", "species_29420" ], "modifiers": [ [ "species_10767951", "catalyst" ] ], "additional_components": [ "species_29420", "P20606", "YPL218W", "P20606", "YPL218W", "species_29438", "YNR026C" ] }, "reaction_10781575": { "compartment": "compartment_70101", "id": "reaction_10781575", "reactome": "R-SCE-5694527", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767892" ], "products": [ "species_10767890", "species_10767946", "species_29372", "species_10767966" ], "modifiers": [ [ "species_10767892", "catalyst" ] ], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "species_29438", "P15303", "YPR181C", "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P15303", "YPR181C", "species_29420", "P20606", "YPL218W", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "species_29438", "P15303", "YPR181C" ] }, "reaction_10765418": { "compartment": "compartment_70101", "id": "reaction_10765418", "reactome": "R-SCE-156910", "name": "Formation of eEF1B complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765409", "species_10765407", "species_10765414" ], "products": [ "species_10765416" ], "modifiers": [], "additional_components": [ "YAL003W", "YAL003W", "YPL048W", "P32471", "YAL003W", "P29547", "YPL048W" ] }, "reaction_10781018": { "compartment": "compartment_70101", "id": "reaction_10781018", "reactome": "R-SCE-5690319", "name": "UCHL1, UCHL3 cleave ubiquitin adducts", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781013", "species_29356" ], "products": [ "species_1131871", "species_10781015" ], "modifiers": [ [ "species_10781013", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35127", "YJR099W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35127", "YJR099W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35127", "YJR099W" ] }, "reaction_10776553": { "compartment": "compartment_13231", "id": "reaction_10776553", "reactome": "R-SCE-4551649", "name": "RANBP2 SUMOylates RANBP2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776540" ], "products": [ "species_10774805", "species_10776550" ], "modifiers": [ [ "species_10763942", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDR002W", "YDL064W", "Q12306", "YDR510W", "P41920", "YDR002W", "P40066", "YER107C", "Q02455", "YKR095W", "P36161", "YKR082W", "P52891", "YDL116W", "P38181", "YBL079W", "P53011", "YGL100W", "P20676", "YOR098C", "P47054", "YJL039C", "Q02630", "YMR047C", "P40368", "YJL061W", "Q04491", "YLR208W", "Q05166", "YDL088C", "P46673", "YJR042W", "P48837", "YGR119C", "P34077", "YFR002W", "P14907", "YJL041W", "P52593", "YML103C", "P35729", "YKL057C", "P32500", "YML031W", "P41920", "YDR002W" ] }, "reaction_10763048": { "compartment": "compartment_70101", "id": "reaction_10763048", "reactome": "R-SCE-72722", "name": "eIF2 activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10762730" ], "products": [ "species_10762728", "species_10762640", "species_29420" ], "modifiers": [ [ "species_10762728", "catalyst" ] ], "additional_components": [ "P09032", "YOR260W", "species_29420", "P32481", "GCD11", "P09064", "SUI3", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P20459", "phospho-SUI2", "P32501", "YDR211W", "P09032", "YOR260W", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P32501", "YDR211W", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "species_29438", "P09032", "YOR260W", "P32502", "YLR291C", "P12754", "YGR083C", "P14741", "YKR026C", "P32501", "YDR211W" ] }, "reaction_10765425": { "compartment": "compartment_70101", "id": "reaction_10765425", "reactome": "R-SCE-156913", "name": "Regeneration of eEF1A:GTP by eEF1B activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10765416", "species_10765420" ], "products": [ "species_10765402", "species_10765422" ], "modifiers": [ [ "species_10765416", "catalyst" ] ], "additional_components": [ "P32471", "YAL003W", "P29547", "YPL048W", "species_29420", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "species_29438", "species_29420", "P32471", "YAL003W", "P29547", "YPL048W", "P32471", "YAL003W", "P29547", "YPL048W" ] }, "reaction_10781034": { "compartment": "compartment_70101", "id": "reaction_10781034", "reactome": "R-SCE-5690808", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781025", "species_29356" ], "products": [ "species_10781031", "species_10781029" ], "modifiers": [ [ "species_10781025", "catalyst" ] ], "additional_components": [ "P35127", "YJR099W", "Q03919", "YDR139C", "YDR139C", "P35127", "YJR099W", "Q03919", "YDR139C", "P35127", "YJR099W", "Q03919", "YDR139C" ] }, "reaction_10785911": { "compartment": "compartment_70101", "id": "reaction_10785911", "reactome": "R-SCE-8853514", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785909" ], "products": [ "species_10762930", "species_10760568" ], "modifiers": [ [ "species_10785902", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P50101", "YMR304W", "P35127", "YJR099W" ] }, "reaction_10785922": { "compartment": "compartment_70101", "id": "reaction_10785922", "reactome": "R-SCE-8853515", "name": "OTULIN,USP5 cleaves UBC yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785919" ], "products": [ "species_10760592", "species_10760600", "species_10760624", "species_10760616", "species_10760584", "species_10760576", "species_10760632", "species_10760608", "species_10760568" ], "modifiers": [ [ "species_10780500", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YBR058C" ] }, "reaction_10770390": { "compartment": "compartment_12045", "id": "reaction_10770390", "reactome": "R-SCE-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449221", "species_110614" ], "products": [ "species_449299", "species_110094" ], "modifiers": [ [ "species_10770387", "catalyst" ] ], "additional_components": [ "YMR013C" ] }, "reaction_10787545": { "compartment": "compartment_70101", "id": "reaction_10787545", "reactome": "R-SCE-8951656", "name": "NEDD8-UBA3:NAE1 binds a second NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781027", "species_113592", "species_10787538" ], "products": [ "species_10787543", "species_111294", "species_76577" ], "modifiers": [], "additional_components": [ "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C", "Q12059", "YPL003W", "Q99344", "YPR066W", "Q03919", "YDR139C" ] }, "reaction_10781572": { "compartment": "compartment_12045", "id": "reaction_10781572", "reactome": "R-SCE-5694522", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767890", "species_10767870", "species_10767966" ], "products": [ "species_10767892" ], "modifiers": [], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P15303", "YPR181C", "P20606", "YPL218W", "species_29438", "P38810", "YHR098C", "P53953", "YNL049C", "P40482", "YIL109C", "P15303", "YPR181C", "P25385", "YLR078C", "Q01590", "YLR026C", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "species_29438", "P15303", "YPR181C" ] }, "reaction_10763045": { "compartment": "compartment_70101", "id": "reaction_10763045", "reactome": "R-SCE-72697", "name": "Start codon recognition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762638", "species_10762624", "species_72617", "species_10762680", "species_10762685" ], "products": [ "species_10762638", "species_10762624", "species_72617", "species_10762680", "species_10762685" ], "modifiers": [ [ "species_72617", "catalyst" ] ], "additional_components": [ "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "YMR260C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "YPR041W", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "YMR260C", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CH08", "RPL40A", "P0C0W1", "RPS22A", "P0CX31", "RPS24A", "P07260", "YOL139C", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P0CX48", "RPS11B", "P32481", "GCD11", "P05756", "RPS13", "Q04067", "YDR429C", "P0CX37", "RPS6A", "P38711", "RPS27B", "P0CX30", "RPS23B", "P38249", "YBR079C", "P26783", "RPS5", "P41057", "RPS29A", "P39938", "RPS26A", "P05759", "RPS31", "P0CH09", "RPL40B", "Q3E754", "RPS21B", "P0CX39", "RPS8A", "P07280", "RPS19A", "P0CX38", "RPS6B", "P39516", "RPS14B", "P0CX52", "RPS16B", "P35997", "RPS27A", "P09064", "SUI3", "P06103", "YOR361C", "Q08745", "RPS10A", "P46784", "RPS10B", "P06367", "RPS14A", "P20459", "phospho-SUI2", "P40217", "YMR146C", "P0CX32", "RPS24B", "P10081", "YKR059W", "P0CX35", "RPS4A", "P32497", "YMR309C", "P23248", "RPS1B", "P0CX47", "RPS11A", "P39936", "YGL049C", "Q05775", "YLR192C", "P0CX56", "RPS18B", "P26786", "RPS7A", "species_29438", "Q01855", "RPS15", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P14127", "RPS17B", "P38912", "YMR260C", "YPR041W" ] }, "reaction_10762693": { "compartment": "compartment_70101", "id": "reaction_10762693", "reactome": "R-SCE-72631", "name": "Formation of the cap-binding eIF4F complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762672", "species_10762660", "species_10762655" ], "products": [ "species_10762674" ], "modifiers": [], "additional_components": [ "P39936", "YGL049C", "P39935", "YGR162W", "YOL139C", "P10081", "YKR059W", "P39936", "YGL049C", "P07260", "YOL139C", "P10081", "YKR059W", "P39935", "YGR162W" ] }, "reaction_10784717": { "compartment": "compartment_20699", "id": "reaction_10784717", "reactome": "R-SCE-6809014", "name": "cis-Golgi cis-SNARE binds NSF and SNAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10784713" ], "products": [ "species_10784715" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "P25385", "YLR078C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P25385", "YLR078C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W" ] }, "reaction_10774816": { "compartment": "compartment_7660", "id": "reaction_10774816", "reactome": "R-SCE-2993780", "name": "Transfer of SUMO1 from E1 to UBE2I (UBC9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774753", "species_10774805" ], "products": [ "species_10774813", "species_10774738" ], "modifiers": [ [ "species_10774738", "catalyst" ] ], "additional_components": [ "P52488", "YDR390C", "Q06624", "YPR180W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W", "P52488", "YDR390C", "Q06624", "YPR180W", "P52488", "YDR390C", "Q06624", "YPR180W" ] }, "reaction_10785335": { "compartment": "compartment_6791047", "id": "reaction_10785335", "reactome": "R-SCE-6814833", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785330" ], "products": [ "species_10785328", "species_10781345" ], "modifiers": [ [ "species_10785330", "catalyst" ] ], "additional_components": [ "P01123", "YFL038C", "species_29438", "P43570", "YFL027C", "YFL027C", "species_29420", "P01123", "YFL038C", "P01123", "YFL038C", "species_29438", "P43570", "YFL027C" ] }, "reaction_10770416": { "compartment": "compartment_70101", "id": "reaction_10770416", "reactome": "R-SCE-446201", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532562" ], "products": [ "species_532531" ], "modifiers": [ [ "species_10770411", "catalyst" ] ], "additional_components": [ "YFL045C" ] }, "reaction_10766770": { "compartment": "compartment_70101", "id": "reaction_10766770", "reactome": "R-SCE-191414", "name": "MVD decarboxylates MVA5PP to IPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191403" ], "products": [ "species_29370", "species_191362", "species_113528", "species_29372" ], "modifiers": [ [ "species_10766767", "catalyst" ] ], "additional_components": [ "P32377", "YNR043W" ] }, "reaction_10767972": { "compartment": "compartment_12045", "id": "reaction_10767972", "reactome": "R-SCE-204008", "name": "SEC31:SEC13 and v-SNARE recruitment", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767898", "species_10767824", "species_10767811" ], "products": [ "species_10767900" ], "modifiers": [], "additional_components": [ "P25385", "YLR078C", "Q01590", "YLR026C", "P48415", "YPL085W", "P38810", "YHR098C", "P20606", "YPL218W", "P53953", "YNL049C", "P40482", "YIL109C", "species_29438", "P15303", "YPR181C", "P36015", "YKL196C", "P22214", "YLR268W", "Q04491", "YLR208W", "Q12204", "YOR022C", "P38968", "YDL195W", "P25385", "YLR078C", "P48415", "YPL085W", "P38810", "YHR098C", "P20606", "YPL218W", "species_29438", "P22214", "YLR268W", "P38968", "YDL195W", "Q01590", "YLR026C", "Q04491", "YLR208W", "P53953", "YNL049C", "P40482", "YIL109C", "Q12204", "YOR022C", "P36015", "YKL196C", "P15303", "YPR181C" ] }, "reaction_10768207": { "compartment": "compartment_876", "id": "reaction_10768207", "reactome": "R-SCE-265177", "name": "Exocyst complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768198", "species_10768183", "species_10768188", "species_10768193", "species_10768178", "species_10768173", "species_10768168", "species_10768203" ], "products": [ "species_10768205" ], "modifiers": [], "additional_components": [ "YIL068C", "YGL233W", "YBR102C", "YER008C", "YLR166C", "YDR166C", "YPR055W", "YJL085W", "P38261", "YBR102C", "P33332", "YER008C", "P89102", "YDR166C", "P32844", "YIL068C", "Q06245", "YLR166C", "P22224", "YGL233W", "P32855", "YPR055W", "P19658", "YJL085W" ] }, "reaction_10783818": { "compartment": "compartment_70101", "id": "reaction_10783818", "reactome": "R-SCE-6800138", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10783797" ], "products": [ "species_71285", "species_10783804" ], "modifiers": [ [ "species_10783815", "catalyst" ] ], "additional_components": [ "P05453", "SUP35", "P12385", "SUP45", "species_29438", "P05453", "SUP35", "P12385", "SUP45", "species_29438", "P53738", "TRM112", "Q03920", "YDR140W" ] }, "reaction_10776658": { "compartment": "compartment_7660", "id": "reaction_10776658", "reactome": "R-SCE-4615873", "name": "PIAS2-2 SUMOylates SUZ12 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776647", "species_10774813" ], "products": [ "species_10774805", "species_10776655" ], "modifiers": [ [ "species_10774918", "catalyst" ] ], "additional_components": [ "YFL049W", "P50623", "YDL064W", "Q12306", "YDR510W", "YDL064W", "Q12306", "YDR510W", "P43554", "YFL049W", "Q04195", "YDR409W", "Q12216", "YOR156C" ] }, "reaction_10770424": { "compartment": "compartment_17957", "id": "reaction_10770424", "reactome": "R-SCE-446202", "name": "Addition of the first glucose to the N-glycan precursor by ALG6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449371", "species_532542" ], "products": [ "species_449311", "species_449649" ], "modifiers": [ [ "species_10770421", "catalyst" ] ], "additional_components": [ "YOR002W" ] }, "reaction_10776717": { "compartment": "compartment_7660", "id": "reaction_10776717", "reactome": "R-SCE-4641345", "name": "SUMOylation of TOP2B with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776708" ], "products": [ "species_10776715", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YNL088W", "P06786", "YNL088W", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10776630": { "compartment": "compartment_7660", "id": "reaction_10776630", "reactome": "R-SCE-4570528", "name": "SUMOylation of XPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776620" ], "products": [ "species_10776628", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YDR314C", "Q12306", "YDR510W", "Q06665", "YDR314C", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10785225": { "compartment": "compartment_70101", "id": "reaction_10785225", "reactome": "R-SCE-6814120", "name": "ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785223" ], "products": [ "species_10785217", "species_29372" ], "modifiers": [], "additional_components": [ "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_113592", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W" ] }, "reaction_10771324": { "compartment": "compartment_17957", "id": "reaction_10771324", "reactome": "R-SCE-901047", "name": "Binding of ERp57", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771171", "species_10771320" ], "products": [ "species_10771322" ], "modifiers": [], "additional_components": [ "P32474", "YDR518W", "P17967", "YCL043C", "P27825", "YAL058W", "CHEBI:59080", "P32474", "YDR518W", "P27825", "YAL058W", "CHEBI:59080", "P17967", "YCL043C" ] }, "reaction_10781764": { "compartment": "compartment_70101", "id": "reaction_10781764", "reactome": "R-SCE-6781953", "name": "YOD1 binds VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781760", "species_10777462" ], "products": [ "species_10781762" ], "modifiers": [], "additional_components": [ "YFL044C", "YDL126C", "P43558", "YFL044C", "P25694", "YDL126C" ] }, "reaction_10771979": { "compartment": "compartment_20699", "id": "reaction_10771979", "reactome": "R-SCE-964830", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964828" ], "products": [ "species_964740", "species_964752" ], "modifiers": [ [ "species_10771968", "catalyst" ] ], "additional_components": [ "YLR057W" ] }, "reaction_10787190": { "compartment": "compartment_984", "id": "reaction_10787190", "reactome": "R-SCE-8940388", "name": "GPLD1 hydrolyses GPI-anchors from proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787165", "species_109276" ], "products": [ "species_2197633", "species_10787182" ], "modifiers": [ [ "species_10787187", "catalyst" ] ], "additional_components": [ "P11491", "YDR481C", "Q07825", "YLL029W", "P11491", "YDR481C", "Q07825", "YLL029W", "YJL132W" ] }, "reaction_10777575": { "compartment": "compartment_70101", "id": "reaction_10777575", "reactome": "R-SCE-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777564", "species_71284" ], "products": [ "species_71285", "species_10777567" ], "modifiers": [ [ "species_10777572", "catalyst" ] ], "additional_components": [ "YLR172C" ] }, "reaction_10785227": { "compartment": "compartment_70101", "id": "reaction_10785227", "reactome": "R-SCE-6814124", "name": "ATP binds G-protein beta associated TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10785217" ], "products": [ "species_29370", "species_10785223" ], "modifiers": [], "additional_components": [ "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_29370", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W", "P39079", "YDR188W", "P18851", "YOR212W", "P42943", "YJL111W", "species_113592", "P39078", "YDL143W", "P39076", "YIL142W", "P39077", "YJL014W", "P12612", "YDR212W", "P47079", "YJL008C", "P40413", "YJR064W" ] }, "reaction_10776565": { "compartment": "compartment_7660", "id": "reaction_10776565", "reactome": "R-SCE-4568863", "name": "SUMOylation of RAD52 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10764167" ], "products": [ "species_10774805", "species_10776563" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YML032C", "YDL064W", "P06778", "YML032C", "Q12306", "YDR510W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10776732": { "compartment": "compartment_7660", "id": "reaction_10776732", "reactome": "R-SCE-4641362", "name": "SUMOylation of TOP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774813", "species_10776722" ], "products": [ "species_10776730", "species_10774805" ], "modifiers": [ [ "species_10774813", "catalyst" ] ], "additional_components": [ "P50623", "YDL064W", "Q12306", "YDR510W", "YOL006C", "P04786", "YOL006C", "Q12306", "YDR510W", "YDL064W", "P50623", "YDL064W", "Q12306", "YDR510W" ] }, "reaction_10787048": { "compartment": "compartment_70101", "id": "reaction_10787048", "reactome": "R-SCE-8931974", "name": "N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10765400" ], "products": [ "species_10787040", "species_71285" ], "modifiers": [ [ "species_10787045", "catalyst" ] ], "additional_components": [ "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7", "YGR001C" ] }, "reaction_10765485": { "compartment": "compartment_17957", "id": "reaction_10765485", "reactome": "R-SCE-162683", "name": "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_8855661" ], "products": [ "species_76194", "species_8855666" ], "modifiers": [ [ "species_10765482", "catalyst" ] ], "additional_components": [ "YJL091C" ] }, "reaction_10785867": { "compartment": "compartment_70101", "id": "reaction_10785867", "reactome": "R-SCE-8852133", "name": "UBA1 conjugates ubiquitin to UBA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785770" ], "products": [ "species_10785692", "species_76577" ], "modifiers": [ [ "species_10785770", "catalyst" ] ], "additional_components": [ "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P22515", "YKL210W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A" ] }, "reaction_10768446": { "compartment": "compartment_70101", "id": "reaction_10768446", "reactome": "R-SCE-351948", "name": "Mitochondrial recruitment of Drp1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768442" ], "products": [ "species_10768444" ], "modifiers": [ [ "species_10768426", "catalyst" ] ], "additional_components": [ "YKR001C", "YKR001C", "YDL072C" ] }, "reaction_10768440": { "compartment": "compartment_13231", "id": "reaction_10768440", "reactome": "R-SCE-351947", "name": "Nuclear translocation of catalytic domain of Mst3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768434" ], "products": [ "species_10768438" ], "modifiers": [], "additional_components": [ "YHR102W", "YHR102W" ] }, "reaction_10768282": { "compartment": "compartment_7660", "id": "reaction_10768282", "reactome": "R-SCE-266204", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768278", "species_29428" ], "products": [ "species_10768280" ], "modifiers": [], "additional_components": [ "Q03435", "YDL002C", "Q02486", "YMR072W", "P33417", "YKL032C", "Q03973", "YDR174W", "P11633", "YBR089C-A", "Q03435", "YDL002C", "Q02486", "YMR072W", "P33417", "YKL032C", "Q03973", "YDR174W", "P11633", "YBR089C-A" ] }, "reaction_10786382": { "compartment": "compartment_70616", "id": "reaction_10786382", "reactome": "R-SCE-8867344", "name": "OMA1 hydrolyses OPA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_10786358" ], "products": [ "species_10786366", "species_10786374" ], "modifiers": [ [ "species_10786379", "catalyst" ] ], "additional_components": [ "P54861", "YLL001W", "P21576", "YKR001C", "P32266", "YOR211C", "P54861", "YLL001W", "P21576", "YKR001C", "P32266", "YOR211C", "P54861", "YLL001W", "P21576", "YKR001C", "P32266", "YOR211C", "YKR087C" ] }, "reaction_10761417": { "compartment": "compartment_5460", "id": "reaction_10761417", "reactome": "R-SCE-70501", "name": "Pyruvate + CO2 + ATP => ADP + Orthophosphate + Oxaloacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29376", "species_113557", "species_113593" ], "products": [ "species_113548", "species_113581", "species_113587" ], "modifiers": [ [ "species_10761414", "catalyst" ], [ "species_113559", "catalyst" ] ], "additional_components": [ "P11154", "YGL062W", "species_199207", "species_113527" ] }, "reaction_10761343": { "compartment": "compartment_70101", "id": "reaction_10761343", "reactome": "R-SCE-70482", "name": "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_29800" ], "products": [ "species_29578", "species_29360", "species_29372" ], "modifiers": [ [ "species_10761261", "catalyst" ] ], "additional_components": [ "P00360", "YJL052W", "P00358", "YJR009C", "P00359", "YGR192C" ] }, "reaction_10768527": { "compartment": "compartment_70101", "id": "reaction_10768527", "reactome": "R-SCE-372449", "name": "phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] => phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_372364", "species_76190" ], "products": [ "species_29654", "species_29492" ], "modifiers": [ [ "species_10764027", "catalyst" ] ], "additional_components": [ "YBR291C" ] }, "reaction_10761339": { "compartment": "compartment_70101", "id": "reaction_10761339", "reactome": "R-SCE-70479", "name": "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30014", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10761336", "catalyst" ], [ "species_76577", "inhibitor" ] ], "additional_components": [ "P09201", "YLR377C", "species_109496" ] }, "reaction_10762171": { "compartment": "compartment_5460", "id": "reaction_10762171", "reactome": "R-SCE-71783", "name": "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113587", "species_113529" ], "products": [ "species_113526", "species_113544" ], "modifiers": [ [ "species_10761676", "catalyst" ] ], "additional_components": [ "P17505", "YKL085W" ] }, "reaction_10761407": { "compartment": "compartment_70101", "id": "reaction_10761407", "reactome": "R-SCE-70494", "name": "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29492", "species_29356" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10761404", "catalyst" ] ], "additional_components": [ "P42222", "YMR323W", "P00924", "YGR254W", "P00925", "YHR174W", "P0CX11", "YPL281C", "P0CX10", "YOR393W", "species_109496" ] }, "reaction_10761341": { "compartment": "compartment_70101", "id": "reaction_10761341", "reactome": "R-SCE-70481", "name": "D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29578" ], "products": [ "species_75970" ], "modifiers": [ [ "species_10761271", "catalyst" ] ], "additional_components": [ "P00942", "YDR050C" ] }, "reaction_10768555": { "compartment": "compartment_70101", "id": "reaction_10768555", "reactome": "R-SCE-372843", "name": "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_113544" ], "products": [ "species_113548", "species_198498" ], "modifiers": [ [ "species_10768552", "catalyst" ] ], "additional_components": [ "YLR348C" ] }, "reaction_10761359": { "compartment": "compartment_70101", "id": "reaction_10761359", "reactome": "R-SCE-70486", "name": "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29728" ], "products": [ "species_29370", "species_29800" ], "modifiers": [ [ "species_10761356", "catalyst" ] ], "additional_components": [ "P00560", "YCR012W", "species_109496" ] }, "reaction_10788348": { "compartment": "compartment_70101", "id": "reaction_10788348", "reactome": "R-SCE-9020257", "name": "LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024893", "species_29356" ], "products": [ "species_9024879" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10788372": { "compartment": "compartment_70101", "id": "reaction_10788372", "reactome": "R-SCE-9024890", "name": "LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024873" ], "products": [ "species_9024886" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10784338": { "compartment": "compartment_70101", "id": "reaction_10784338", "reactome": "R-SCE-6807105", "name": "Monoubiquitinated PTEN translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784332" ], "products": [ "species_10784336" ], "modifiers": [], "additional_components": [ "YNL128W", "YNL128W" ] }, "reaction_10784343": { "compartment": "compartment_7660", "id": "reaction_10784343", "reactome": "R-SCE-6807118", "name": "USP7 deubiquitinates monoubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10784336" ], "products": [ "species_10784340", "species_10760537" ], "modifiers": [ [ "species_10779695", "catalyst" ] ], "additional_components": [ "YNL128W", "YNL128W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YMR304W" ] }, "reaction_10784345": { "compartment": "compartment_7660", "id": "reaction_10784345", "reactome": "R-SCE-6807126", "name": "Deubiquitinated PTEN translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784340" ], "products": [ "species_10767316" ], "modifiers": [], "additional_components": [ "YNL128W", "YNL128W" ] }, "reaction_10769655": { "compartment": "compartment_876", "id": "reaction_10769655", "reactome": "R-SCE-425822", "name": "K+-independent Li+/Ca2+ exchanger transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_425815" ], "products": [ "species_425810", "species_74112" ], "modifiers": [ [ "species_10769652", "catalyst" ] ], "additional_components": [ "YJR106W" ] }, "reaction_10787919": { "compartment": "compartment_7660", "id": "reaction_10787919", "reactome": "R-SCE-9009533", "name": "TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763232", "species_10763417", "species_10787915" ], "products": [ "species_10787917" ], "modifiers": [], "additional_components": [ "P32774", "YKL058W", "P32773", "YOR194C", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P42944", "YJL110C", "P43574", "YFL021W", "P25364", "YCR065W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P18494", "YER040W", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P42944", "YJL110C", "P32774", "YKL058W", "P32773", "YOR194C", "P43574", "YFL021W", "P25364", "YCR065W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P13393", "SPT15", "P18494", "YER040W" ] }, "reaction_10787967": { "compartment": "compartment_7660", "id": "reaction_10787967", "reactome": "R-SCE-9012319", "name": "p-TEFb phosphorylates serine 2 in RNA polymerase II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10787962" ], "products": [ "species_113582", "species_10787964" ], "modifiers": [ [ "species_10787962", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "CHEBI:50114", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q05949", "YLR226W", "P34087", "YDR404C", "P22139", "RPB10", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "CHEBI:50114", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "Q05949", "YLR226W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "CHEBI:50114", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q05949", "YLR226W", "P34087", "YDR404C", "P22139", "RPB10", "P46962", "YJL006C" ] }, "reaction_10787903": { "compartment": "compartment_7660", "id": "reaction_10787903", "reactome": "R-SCE-9009065", "name": "FOXA1 and GATA3 bind to CCND1 promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787891", "species_10787885", "species_10787899" ], "products": [ "species_10772638", "species_10787901", "species_10787879" ], "modifiers": [], "additional_components": [ "P25364", "YCR065W", "P40466", "YIL131C", "P02294", "YBL002W", "P02309", "YBR009C", "Q03125", "YDR043C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "Q12214", "YPR068C", "P42944", "YJL110C", "P43574", "YFL021W", "P18494", "YER040W", "YPR068C", "P42944", "YJL110C", "P02293", "YDR224C", "P25364", "YCR065W", "P04912", "YBL003C", "P04911", "YDR225W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "Q12692", "YOL012C", "P43574", "YFL021W", "P40466", "YIL131C", "P61830", "YBR010W", "P18494", "YER040W", "YDR043C" ] }, "reaction_10787934": { "compartment": "compartment_7660", "id": "reaction_10787934", "reactome": "R-SCE-9011949", "name": "KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787929" ], "products": [ "species_10787931", "species_10776763" ], "modifiers": [ [ "species_10787929", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P39956", "YER169W", "CHEBI:50114", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "CHEBI:50114", "YER169W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P39956", "YER169W", "CHEBI:50114" ] }, "reaction_10788368": { "compartment": "compartment_7660", "id": "reaction_10788368", "reactome": "R-SCE-9023860", "name": "Histone acetyltransferases are recruited to the TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788364", "species_10788356" ], "products": [ "species_10788366" ], "modifiers": [], "additional_components": [ "P38074", "YBR034C", "P42944", "YJL110C", "P32774", "YKL058W", "P25364", "YCR065W", "P13393", "SPT15", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P32773", "YOR194C", "P43574", "YFL021W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P18494", "YER040W", "P34218", "YBL052C", "Q03330", "YGR252W", "P38074", "YBR034C", "P42944", "YJL110C", "P32774", "YKL058W", "P25364", "YCR065W", "P13393", "SPT15", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P34218", "YBL052C", "Q03330", "YGR252W", "P32773", "YOR194C", "P43574", "YFL021W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P18494", "YER040W" ] }, "reaction_10788370": { "compartment": "compartment_7660", "id": "reaction_10788370", "reactome": "R-SCE-9023861", "name": "PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787917", "species_10775032" ], "products": [ "species_10788362" ], "modifiers": [], "additional_components": [ "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P42944", "YJL110C", "P32774", "YKL058W", "P32773", "YOR194C", "P43574", "YFL021W", "P25364", "YCR065W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P13393", "SPT15", "P18494", "YER040W", "YBR034C", "P38074", "YBR034C", "P42944", "YJL110C", "P32774", "YKL058W", "P25364", "YCR065W", "P13393", "SPT15", "CHEBI:142773", "P24783", "YNL112W", "species_193132", "P32773", "YOR194C", "P43574", "YFL021W", "P40466", "YIL131C", "CHEBI:27974", "species_193066", "P18494", "YER040W" ] }, "reaction_10766225": { "compartment": "compartment_13231", "id": "reaction_10766225", "reactome": "R-SCE-170825", "name": "glucokinase [nucleoplasm] => glucokinase [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766223" ], "products": [ "species_10761199" ], "modifiers": [], "additional_components": [ "Q04409", "YDR516C", "Q06204", "YLR446W", "P04806", "YFR053C", "P17709", "YCL040W", "P04807", "YGL253W", "Q04409", "YDR516C", "Q06204", "YLR446W", "P04806", "YFR053C", "P17709", "YCL040W", "P04807", "YGL253W" ] }, "reaction_10767350": { "compartment": "compartment_7660", "id": "reaction_10767350", "reactome": "R-SCE-199839", "name": "AKT can phosphorylate RSK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10767323" ], "products": [ "species_113582", "species_10767327" ], "modifiers": [ [ "species_10767347", "catalyst" ] ], "additional_components": [ "YBR028C", "YBR028C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10767701": { "compartment": "compartment_876", "id": "reaction_10767701", "reactome": "R-SCE-202692", "name": "PIP3 binds to RhoA and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765227", "species_179838" ], "products": [ "species_10767699" ], "modifiers": [], "additional_components": [ "YPR165W", "P06780", "YPR165W", "species_179838" ] }, "reaction_10788521": { "compartment": "compartment_70101", "id": "reaction_10788521", "reactome": "R-SCE-9603279", "name": "PIP3 recruits PDK1 and AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767662", "species_179838", "species_10769080" ], "products": [ "species_10788519" ], "modifiers": [], "additional_components": [ "YOL100W", "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "Q12236", "YOL100W", "P11792", "YHR205W" ] }, "reaction_10788567": { "compartment": "compartment_17947", "id": "reaction_10788567", "reactome": "R-SCE-9603775", "name": "PEX3:PEX19:class I PMP dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788555" ], "products": [ "species_10768844", "species_10788565", "species_10768864" ], "modifiers": [], "additional_components": [ "P53112", "PEX14", "P28737", "YGR028W", "P28795", "YDR329C", "Q07418", "YDL065C", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C", "YDR329C", "P53112", "PEX14", "P28737", "YGR028W", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C", "YDL065C" ] }, "reaction_10788569": { "compartment": "compartment_17947", "id": "reaction_10788569", "reactome": "R-SCE-9603784", "name": "PEX19:class I PMP binds PEX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788553", "species_10768844" ], "products": [ "species_10788555" ], "modifiers": [], "additional_components": [ "P53112", "PEX14", "P28737", "YGR028W", "Q07418", "YDL065C", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C", "YDR329C", "P53112", "PEX14", "P28737", "YGR028W", "P28795", "YDR329C", "Q07418", "YDL065C", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C" ] }, "reaction_10788571": { "compartment": "compartment_70101", "id": "reaction_10788571", "reactome": "R-SCE-9603804", "name": "PEX19 binds class I peroxisomal membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788551", "species_10768864" ], "products": [ "species_10788553" ], "modifiers": [], "additional_components": [ "P53112", "PEX14", "P28737", "YGR028W", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C", "YDL065C", "P53112", "PEX14", "P28737", "YGR028W", "Q07418", "YDL065C", "P34230", "YKL188C", "P80667", "PEX13", "Q04458", "YMR110C", "Q04370", "YMR026C", "P41909", "YPL147W", "Q06563", "YLR251W", "Q12462", "YOL147C", "P40515", "YIL065C" ] }, "reaction_10765200": { "compartment": "compartment_7660", "id": "reaction_10765200", "reactome": "R-SCE-113430", "name": "Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764338" ], "products": [ "species_10764338" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10764341": { "compartment": "compartment_7660", "id": "reaction_10764341", "reactome": "R-SCE-77071", "name": "Phosphorylation (Ser5) of RNA pol II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10764338" ], "products": [ "species_113582", "species_10764334" ], "modifiers": [ [ "species_10764338", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "P16370", "YIL021W", "Q03290", "YDR460W", "Q12004", "YPR056W", "P41895", "YGR186W", "Q02939", "YPL122C", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P38902", "YOL005C", "P32776", "YDR311W", "P06242", "YDL108W", "Q04673", "YLR005W", "P20433", "YJL140W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q03290", "YDR460W", "P16370", "YIL021W", "Q12004", "YPR056W", "Q02939", "YPL122C", "P41895", "YGR186W", "P40422", "RPC10", "P34087", "YDR404C", "P22139", "RPB10", "P06839", "RAD3" ] }, "reaction_10764281": { "compartment": "compartment_7660", "id": "reaction_10764281", "reactome": "R-SCE-76056", "name": "Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764229", "species_10764277" ], "products": [ "species_10764279" ], "modifiers": [], "additional_components": [ "Q06339", "YDR362C", "P46678", "BDP1", "P29056", "BRF1", "P32367", "TFC1", "P33339", "TFC4", "P32805", "YGL254W", "P34111", "TFC3", "P13393", "SPT15", "P20434", "RPB5", "P32910", "RPC34", "P35718", "RPC25", "P20435", "RPO26", "P25441", "RPC53", "P07703", "RPC40", "P17890", "RPC31", "P22276", "RET1", "P20436", "RPB8", "P32349", "RPC82", "P47076", "RPC17", "P40422", "RPC10", "Q04307", "RPC11", "P22139", "RPB10", "P04051", "RPO31", "P20434", "RPB5", "Q06339", "YDR362C", "P46678", "BDP1", "P29056", "BRF1", "P32910", "RPC34", "P35718", "RPC25", "P32367", "TFC1", "P20435", "RPO26", "P25441", "RPC53", "P07703", "RPC40", "P17890", "RPC31", "P22276", "RET1", "P13393", "SPT15", "P20436", "RPB8", "P32349", "RPC82", "P47076", "RPC17", "P33339", "TFC4", "P40422", "RPC10", "Q04307", "RPC11", "P32805", "YGL254W", "P22139", "RPB10", "P04051", "RPO31", "P34111", "TFC3" ] }, "reaction_10764473": { "compartment": "compartment_7660", "id": "reaction_10764473", "reactome": "R-SCE-83805", "name": "Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764469", "species_10764277" ], "products": [ "species_10764471" ], "modifiers": [], "additional_components": [ "Q06339", "YDR362C", "P46678", "BDP1", "P29056", "BRF1", "P32367", "TFC1", "P33339", "TFC4", "P34111", "TFC3", "P13393", "SPT15", "P20434", "RPB5", "P32910", "RPC34", "P35718", "RPC25", "P20435", "RPO26", "P25441", "RPC53", "P07703", "RPC40", "P17890", "RPC31", "P22276", "RET1", "P20436", "RPB8", "P32349", "RPC82", "P47076", "RPC17", "P40422", "RPC10", "Q04307", "RPC11", "P22139", "RPB10", "P04051", "RPO31", "P20434", "RPB5", "Q06339", "YDR362C", "P46678", "BDP1", "P29056", "BRF1", "P32910", "RPC34", "P35718", "RPC25", "P32367", "TFC1", "P20435", "RPO26", "P25441", "RPC53", "P07703", "RPC40", "P17890", "RPC31", "P22276", "RET1", "P13393", "SPT15", "P20436", "RPB8", "P32349", "RPC82", "P47076", "RPC17", "P33339", "TFC4", "P40422", "RPC10", "Q04307", "RPC11", "P22139", "RPB10", "P04051", "RPO31", "P34111", "TFC3" ] }, "reaction_10764192": { "compartment": "compartment_7660", "id": "reaction_10764192", "reactome": "R-SCE-76052", "name": "Binding of TFIIIA To type 1 Promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76050", "species_10764188" ], "products": [ "species_10764190" ], "modifiers": [], "additional_components": [ "YGL254W", "P32805", "YGL254W" ] }, "reaction_10765180": { "compartment": "compartment_7660", "id": "reaction_10765180", "reactome": "R-SCE-112396", "name": "Separation of elongating transcript from template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765176" ], "products": [ "species_10765178" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765194": { "compartment": "compartment_7660", "id": "reaction_10765194", "reactome": "R-SCE-113412", "name": "Pol II elongation complex moves on the template as transcript elongates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10765164" ], "products": [ "species_9757634", "species_10765176" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765188": { "compartment": "compartment_7660", "id": "reaction_10765188", "reactome": "R-SCE-113407", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764987", "species_10764978" ], "products": [ "species_10764989" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10", "P27692", "YML010W", "P32914", "YGR063C", "P41896", "YGR005C", "P20434", "RPB5", "P27692", "YML010W", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P32914", "YGR063C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10" ] }, "reaction_10765166": { "compartment": "compartment_7660", "id": "reaction_10765166", "reactome": "R-SCE-112385", "name": "Addition of nucleotides leads to transcript elongation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10765162" ], "products": [ "species_10763293", "species_10765164" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "Q04673", "YLR005W", "Q00578", "YIL143C", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53861", "YNL230C", "P53930", "YNL107W", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "Q03290", "YDR460W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P06839", "RAD3", "P46962", "YJL006C", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "P41896", "YGR005C", "P20434", "RPB5", "Q02793", "SKI8", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P53064", "YGL244W", "P38902", "YOL005C", "P38439", "YOR123C", "P35189", "YPL129W", "P32914", "YGR063C", "P23615", "YGR116W", "species_6806881", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05949", "YLR226W", "P89105", "YOL145C", "P07273", "YGL043W", "P38351", "YBR279W", "P22139", "RPB10", "P53930", "YNL107W", "P53861", "YNL230C", "Q99314", "YOR213C", "P27692", "YML010W", "P04050", "YDL140C", "Q06697", "YLR418C", "P20433", "YJL140W", "P16370", "YIL021W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "Q04636", "YML069W", "P40422", "RPC10", "Q03254", "YMR277W", "P34087", "YDR404C", "Q06505", "YPR133C", "P46962", "YJL006C" ] }, "reaction_10765033": { "compartment": "compartment_7660", "id": "reaction_10765033", "reactome": "R-SCE-112383", "name": "Hypophosphorylation of RNA Pol II CTD by FCP1P protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762306", "species_10763293", "species_10764985" ], "products": [ "species_10764987", "species_10763293" ], "modifiers": [ [ "species_10764985", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P20435", "RPO26", "P04050", "YDL140C", "P38902", "YOL005C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "YMR277W", "P41896", "YGR005C", "P20434", "RPB5", "P04050", "YDL140C", "P20435", "RPO26", "P38902", "YOL005C", "P34160", "YMR125W", "P20433", "YJL140W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "Q03254", "YMR277W", "Q08920", "YPL178W", "P34087", "YDR404C", "P22139", "RPB10", "Q04673", "YLR005W", "Q00578", "YIL143C", "Q03290", "YDR460W", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06839", "RAD3", "P06242", "YDL108W", "YMR277W" ] }, "reaction_10788729": { "compartment": "compartment_876", "id": "reaction_10788729", "reactome": "R-SCE-9632858", "name": "PRKCZ autophosphorylates downstream of estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10788721" ], "products": [ "species_29370", "species_10788726" ], "modifiers": [ [ "species_10788721", "catalyst" ] ], "additional_components": [ "P24583", "YBL105C", "species_179838", "Q12236", "YOL100W", "P24583", "YBL105C", "species_179838", "Q12236", "YOL100W", "P24583", "YBL105C", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10788731": { "compartment": "compartment_7660", "id": "reaction_10788731", "reactome": "R-SCE-9632910", "name": "ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775860" ], "products": [ "species_10767242" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "P16892", "YBL016W" ] }, "reaction_10788690": { "compartment": "compartment_876", "id": "reaction_10788690", "reactome": "R-SCE-9625814", "name": "SPHK1 phosphorylates sphingosine in response to E2 stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1606609" ], "products": [ "species_5218688" ], "modifiers": [ [ "species_10769088", "catalyst" ] ], "additional_components": [ "YLR260W" ] }, "reaction_10786822": { "compartment": "compartment_70101", "id": "reaction_10786822", "reactome": "R-SCE-8875623", "name": "SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29404" ], "products": [ "species_113552", "species_113529" ], "modifiers": [ [ "species_10786819", "catalyst" ] ], "additional_components": [ "Q99297", "YOR222W", "Q03028", "YPL134C" ] }, "reaction_10775307": { "compartment": "compartment_20699", "id": "reaction_10775307", "reactome": "R-SCE-3247836", "name": "Retromer recycles WLS to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775301" ], "products": [ "species_10775305" ], "modifiers": [], "additional_components": [ "Q08826", "YOR357C", "P38759", "YHR012W", "P40335", "YJL053W", "P34110", "YJL154C", "Q08826", "YOR357C", "P38759", "YHR012W", "P40335", "YJL053W", "P34110", "YJL154C" ] }, "reaction_10768807": { "compartment": "compartment_70101", "id": "reaction_10768807", "reactome": "R-SCE-381727", "name": "RAP1A exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768805", "species_29438" ], "products": [ "species_10768481", "species_29420" ], "modifiers": [], "additional_components": [ "species_111349", "P13856", "YGR152C", "species_29438", "P13856", "YGR152C" ] }, "reaction_10781313": { "compartment": "compartment_5460", "id": "reaction_10781313", "reactome": "R-SCE-5694018", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781300", "species_113526" ], "products": [ "species_10781283", "species_29362", "species_113529" ], "modifiers": [ [ "species_10781310", "catalyst" ] ], "additional_components": [ "CHEBI:50746", "P39726", "YAL044C", "YAL044C", "P09624", "YFL018C", "species_113596" ] }, "reaction_10781298": { "compartment": "compartment_5460", "id": "reaction_10781298", "reactome": "R-SCE-5693967", "name": "PXLP-K754-GLDC dimer decarboxylates Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781283", "species_159549" ], "products": [ "species_29376", "species_10781287" ], "modifiers": [ [ "species_10781295", "catalyst" ] ], "additional_components": [ "YAL044C", "CHEBI:14949", "P39726", "YAL044C", "P49095", "YMR189W" ] }, "reaction_10781308": { "compartment": "compartment_5460", "id": "reaction_10781308", "reactome": "R-SCE-5693977", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_10781287" ], "products": [ "species_5693984", "species_10781300", "species_5693978" ], "modifiers": [ [ "species_10781305", "catalyst" ] ], "additional_components": [ "CHEBI:14949", "P39726", "YAL044C", "CHEBI:50746", "P39726", "YAL044C", "YDR019C" ] }, "reaction_10769352": { "compartment": "compartment_876", "id": "reaction_10769352", "reactome": "R-SCE-418582", "name": "G alpha (q) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764870" ], "products": [ "species_10769349" ], "modifiers": [ [ "species_10764870", "catalyst" ] ], "additional_components": [ "species_29438", "P10823", "YER020W", "species_111349", "P10823", "YER020W", "species_29438", "P10823", "YER020W" ] }, "reaction_10765298": { "compartment": "compartment_876", "id": "reaction_10765298", "reactome": "R-SCE-114688", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765293" ], "products": [ "species_10765295" ], "modifiers": [ [ "species_10764872", "catalyst" ] ], "additional_components": [ "P32383", "YPL268W", "species_29438", "species_179856", "P10823", "YER020W", "species_114520", "P32383", "YPL268W", "species_6797635", "species_29438", "P10823", "YER020W", "P32383", "YPL268W", "species_29438", "P10823", "YER020W" ] }, "reaction_10769199": { "compartment": "compartment_876", "id": "reaction_10769199", "reactome": "R-SCE-400015", "name": "Diacylgycerol activates Protein kinase C, alpha type", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765240", "species_114519" ], "products": [ "species_10769197" ], "modifiers": [], "additional_components": [ "YBL105C", "P24583", "YBL105C", "species_6797635" ] }, "reaction_10787442": { "compartment": "compartment_70101", "id": "reaction_10787442", "reactome": "R-SCE-8948039", "name": "FUNDC1 is phosphorylated by CK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787437", "species_113592" ], "products": [ "species_29370", "species_10787440" ], "modifiers": [ [ "species_10774577", "catalyst" ] ], "additional_components": [ "YAL008W", "YAL008W", "P15790", "CKA1", "P38930", "CKB2", "P19454", "CKA2" ] }, "reaction_10787455": { "compartment": "compartment_17906", "id": "reaction_10787455", "reactome": "R-SCE-8948146", "name": "FUNDC1 is phosphorylated by ULK1 at Ser17", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787437", "species_113592" ], "products": [ "species_29370", "species_10787452" ], "modifiers": [ [ "species_10787444", "catalyst" ] ], "additional_components": [ "YAL008W", "YAL008W", "YGL180W" ] }, "reaction_10787722": { "compartment": "compartment_21994", "id": "reaction_10787722", "reactome": "R-SCE-8959571", "name": "LC3 binds the autophagosome membrane Atg5-Atg12 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787718", "species_10777022" ], "products": [ "species_10787720" ], "modifiers": [], "additional_components": [ "P18411", "YAL008W", "P38182", "YBL078C", "Q12380", "YPL149W", "P38316", "YBR217W", "Q12380", "YPL149W", "P18411", "YAL008W", "P38316", "YBR217W", "P38182", "YBL078C" ] }, "reaction_10787446": { "compartment": "compartment_17906", "id": "reaction_10787446", "reactome": "R-SCE-8948136", "name": "ULK1 Translocates to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778616" ], "products": [ "species_10787444" ], "modifiers": [], "additional_components": [ "YGL180W", "YGL180W" ] }, "reaction_10787724": { "compartment": "compartment_70101", "id": "reaction_10787724", "reactome": "R-SCE-8959573", "name": "Phosphorylated FUNDC1 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779041", "species_10787452" ], "products": [ "species_10787718" ], "modifiers": [], "additional_components": [ "YBL078C", "YAL008W", "P18411", "YAL008W", "P38182", "YBL078C" ] }, "reaction_10788643": { "compartment": "compartment_70101", "id": "reaction_10788643", "reactome": "R-SCE-9617595", "name": "SGTA binds mislocalized membrane protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788608", "species_10788577" ], "products": [ "species_10788641" ], "modifiers": [], "additional_components": [ "P33328", "YOR327C", "P31109", "YAL030W", "Q12118", "SGT2", "P33328", "YOR327C", "Q12118", "SGT2", "P31109", "YAL030W" ] }, "reaction_10788616": { "compartment": "compartment_70101", "id": "reaction_10788616", "reactome": "R-SCE-9609921", "name": "SGTA binds Tail-anchored protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788612", "species_10788577" ], "products": [ "species_10788614" ], "modifiers": [], "additional_components": [ "Q01590", "YLR026C", "P33296", "YER100W", "P35179", "YDR086C", "P52871", "YER019C-A", "P32867", "YPL232W", "P33328", "YOR327C", "Q04458", "YMR110C", "P40075", "YER120W", "P38374", "YBR162W-A", "P31109", "YAL030W", "P40312", "YNL111C", "P39926", "YMR183C", "Q12118", "SGT2", "Q01590", "YLR026C", "P33296", "YER100W", "P35179", "YDR086C", "P52871", "YER019C-A", "P32867", "YPL232W", "P33328", "YOR327C", "Q04458", "YMR110C", "P40075", "YER120W", "P38374", "YBR162W-A", "Q12118", "SGT2", "P31109", "YAL030W", "P40312", "YNL111C", "P39926", "YMR183C" ] }, "reaction_10773413": { "compartment": "compartment_876", "id": "reaction_10773413", "reactome": "R-SCE-1640164", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429776", "species_29356" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10773410", "catalyst" ] ], "additional_components": [ "P39997", "YEL016C", "P25353", "YCR026C" ] }, "reaction_10773363": { "compartment": "compartment_876", "id": "reaction_10773363", "reactome": "R-SCE-1606273", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429776", "species_29356" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10773360", "catalyst" ] ], "additional_components": [ "P40015", "YER019W", "species_109496" ] }, "reaction_10785153": { "compartment": "compartment_7660", "id": "reaction_10785153", "reactome": "R-SCE-6811522", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_6810408" ], "products": [ "species_113582", "species_6810412" ], "modifiers": [ [ "species_10785150", "catalyst" ] ], "additional_components": [ "P38994", "YDR208W" ] }, "reaction_10768746": { "compartment": "compartment_5460", "id": "reaction_10768746", "reactome": "R-SCE-380608", "name": "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380598", "species_113526" ], "products": [ "species_380593", "species_29362", "species_113529" ], "modifiers": [ [ "species_10762134", "catalyst" ] ], "additional_components": [ "P40047", "YER073W" ] }, "reaction_10766908": { "compartment": "compartment_70101", "id": "reaction_10766908", "reactome": "R-SCE-194678", "name": "CYP51A1 demethylates LNSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194634", "species_29368" ], "products": [ "species_29366", "species_194644", "species_29460", "species_29356" ], "modifiers": [ [ "species_10766905", "catalyst" ] ], "additional_components": [ "YHR007C" ] }, "reaction_10776925": { "compartment": "compartment_7660", "id": "reaction_10776925", "reactome": "R-SCE-5082384", "name": "HSP70:DNAJB1 binds HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775782", "species_10775812" ], "products": [ "species_10775814" ], "modifiers": [], "additional_components": [ "P36016", "YKL073W", "P25294", "YNL007C", "P22202", "YER103W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P38889", "YHR206W", "P10961", "YGL073W", "P36016", "YKL073W", "P25294", "YNL007C", "P22202", "YER103W", "P38889", "YHR206W", "P09435", "YBL075C", "P10592", "YLL024C", "P10961", "YGL073W", "P10591", "YAL005C" ] }, "reaction_10788335": { "compartment": "compartment_70101", "id": "reaction_10788335", "reactome": "R-SCE-9018824", "name": "RHOT2 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788331", "species_10788314" ], "products": [ "species_10788333" ], "modifiers": [], "additional_components": [ "P32492", "YAL029C", "P38297", "YBR179C", "P19524", "YOR326W", "species_29438", "P39722", "YAL048C", "P32492", "YAL029C", "P38297", "YBR179C", "species_29438", "P19524", "YOR326W", "P39722", "YAL048C" ] }, "reaction_10788319": { "compartment": "compartment_70101", "id": "reaction_10788319", "reactome": "R-SCE-9018814", "name": "RHOT1 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788314", "species_29356" ], "products": [ "species_10788316", "species_29372" ], "modifiers": [ [ "species_10788314", "catalyst" ] ], "additional_components": [ "species_29438", "P39722", "YAL048C", "species_29420", "P39722", "YAL048C", "species_29438", "P39722", "YAL048C" ] }, "reaction_10788329": { "compartment": "compartment_17906", "id": "reaction_10788329", "reactome": "R-SCE-9018815", "name": "RHOT1 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788325", "species_10788314" ], "products": [ "species_10788327" ], "modifiers": [], "additional_components": [ "P32492", "YAL029C", "P19524", "YOR326W", "species_29438", "P39722", "YAL048C", "P32492", "YAL029C", "species_29438", "P19524", "YOR326W", "P39722", "YAL048C" ] }, "reaction_10788337": { "compartment": "compartment_70101", "id": "reaction_10788337", "reactome": "R-SCE-9018826", "name": "RHOT2 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788314", "species_29356" ], "products": [ "species_10788316", "species_29372" ], "modifiers": [ [ "species_10788314", "catalyst" ] ], "additional_components": [ "species_29438", "P39722", "YAL048C", "species_29420", "P39722", "YAL048C", "species_29438", "P39722", "YAL048C" ] }, "reaction_10769669": { "compartment": "compartment_172574", "id": "reaction_10769669", "reactome": "R-SCE-425965", "name": "SLC9A9 exchanges Na+ for H+ across the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_83910", "species_425999" ], "products": [ "species_70106", "species_425977" ], "modifiers": [ [ "species_10769666", "catalyst" ] ], "additional_components": [ "YDR456W" ] }, "reaction_10769676": { "compartment": "compartment_171062", "id": "reaction_10769676", "reactome": "R-SCE-425983", "name": "SLC9A6,7 exchange Na+ for H+ across the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425978", "species_83910" ], "products": [ "species_70106", "species_425971" ], "modifiers": [ [ "species_10769671", "catalyst" ] ], "additional_components": [ "YDR456W" ] }, "reaction_10769681": { "compartment": "compartment_20699", "id": "reaction_10769681", "reactome": "R-SCE-426015", "name": "Na+/H+ exchanger transport (at trans-golgi membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425969", "species_83910" ], "products": [ "species_70106", "species_425958" ], "modifiers": [ [ "species_10769678", "catalyst" ] ], "additional_components": [ "YDR456W" ] }, "reaction_10766728": { "compartment": "compartment_70101", "id": "reaction_10766728", "reactome": "R-SCE-191366", "name": "Squalene 2,3-epoxide cyclizes, forming lanosterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191309" ], "products": [ "species_194634" ], "modifiers": [ [ "species_10766725", "catalyst" ] ], "additional_components": [ "YHR072W" ] }, "reaction_10787021": { "compartment": "compartment_5460", "id": "reaction_10787021", "reactome": "R-SCE-8878815", "name": "Formation of 4Fe-4S cluster on ISCA1:ISCA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787001", "species_10787013" ], "products": [ "species_10786999", "species_10787015" ], "modifiers": [ [ "species_10787019", "catalyst" ] ], "additional_components": [ "CHEBI:33739", "Q02784", "YPL059W", "Q12425", "YPR067W", "Q07821", "YLL027W", "YPL059W", "Q12425", "YPR067W", "CHEBI:49883", "Q07821", "YLL027W" ] }, "reaction_10789204": { "compartment": "compartment_70101", "id": "reaction_10789204", "reactome": "R-SCE-9705714", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_29366", "species_469662" ], "modifiers": [ [ "species_10776525", "catalyst" ] ], "additional_components": [ "YIL049W" ] }, "reaction_10785545": { "compartment": "compartment_984", "id": "reaction_10785545", "reactome": "R-SCE-8851129", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8870906", "species_109276" ], "products": [ "species_8870962", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785539", "catalyst" ] ], "additional_components": [ "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10781870": { "compartment": "compartment_70101", "id": "reaction_10781870", "reactome": "R-SCE-6783221", "name": "HAGH hydrolyses (R)-S-LGSH to GSH and LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694130" ], "products": [ "species_29450", "species_29708" ], "modifiers": [ [ "species_10781867", "catalyst" ] ], "additional_components": [ "species_158417", "Q12320", "YOR040W" ] }, "reaction_10767283": { "compartment": "compartment_70101", "id": "reaction_10767283", "reactome": "R-SCE-198845", "name": "CYB5A:heme reduces Asc.- to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767269", "species_1497805" ], "products": [ "species_10767267", "species_198816" ], "modifiers": [ [ "species_10767269", "catalyst" ] ], "additional_components": [ "species_189444", "P40312", "YNL111C", "CHEBI:36144", "P40312", "YNL111C", "species_189444", "P40312", "YNL111C" ] }, "reaction_10771989": { "compartment": "compartment_70101", "id": "reaction_10771989", "reactome": "R-SCE-964958", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964945", "species_113592" ], "products": [ "species_29370", "species_965146" ], "modifiers": [ [ "species_10771986", "catalyst" ] ], "additional_components": [ "species_158417", "P39988", "YEL029C" ] }, "reaction_10769063": { "compartment": "compartment_17951", "id": "reaction_10769063", "reactome": "R-SCE-390291", "name": "acetyl-CoA + carnitine => acetylcarnitine + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390294", "species_353123" ], "products": [ "species_193514", "species_390287" ], "modifiers": [ [ "species_10769058", "catalyst" ] ], "additional_components": [ "YML042W" ] }, "reaction_10773576": { "compartment": "compartment_12045", "id": "reaction_10773576", "reactome": "R-SCE-1676124", "name": "PI4P is dephosphorylated to PI by SACM1L at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806234", "species_29356" ], "products": [ "species_426639", "species_29372" ], "modifiers": [ [ "species_10773573", "catalyst" ] ], "additional_components": [ "YKL212W" ] }, "reaction_10771313": { "compartment": "compartment_70101", "id": "reaction_10771313", "reactome": "R-SCE-893596", "name": "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398", "species_29970" ], "products": [ "species_893615", "species_29432" ], "modifiers": [ [ "species_10771307", "catalyst" ], [ "species_8939576", "inhibitor" ], [ "species_29502", "inhibitor" ] ], "additional_components": [ "P47039", "YJL060W", "CHEBI:55528", "CHEBI:43580" ] }, "reaction_10778606": { "compartment": "compartment_70101", "id": "reaction_10778606", "reactome": "R-SCE-5662466", "name": "XYLB phosphorylates D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5661281", "species_113592" ], "products": [ "species_29370", "species_29790" ], "modifiers": [ [ "species_10778603", "catalyst" ] ], "additional_components": [ "YGR194C" ] }, "reaction_10763390": { "compartment": "compartment_70101", "id": "reaction_10763390", "reactome": "R-SCE-73813", "name": "GAR + 10-Formyl-THF => FGAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111338", "species_419151" ], "products": [ "species_70106", "species_111354", "species_111355" ], "modifiers": [ [ "species_10763376", "catalyst" ] ], "additional_components": [ "YGL234W" ] }, "reaction_10784783": { "compartment": "compartment_17951", "id": "reaction_10784783", "reactome": "R-SCE-6809808", "name": "ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6809801" ], "products": [ "species_6809800" ], "modifiers": [ [ "species_10784780", "catalyst" ] ], "additional_components": [ "P31787", "YGR037C" ] }, "reaction_10774954": { "compartment": "compartment_70101", "id": "reaction_10774954", "reactome": "R-SCE-3095901", "name": "ABCC1 transports cytosolic Cbl to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3000241", "species_29356" ], "products": [ "species_29370", "species_3000125", "species_29372" ], "modifiers": [ [ "species_10768249", "catalyst" ] ], "additional_components": [ "YDR135C" ] }, "reaction_10781339": { "compartment": "compartment_70616", "id": "reaction_10781339", "reactome": "R-SCE-5694137", "name": "PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693984", "species_113521", "species_159549" ], "products": [ "species_200671", "species_379732" ], "modifiers": [ [ "species_10781336", "catalyst" ] ], "additional_components": [ "P37291", "YLR058C", "P37292", "YBR263W" ] }, "reaction_10762043": { "compartment": "compartment_70101", "id": "reaction_10762043", "reactome": "R-SCE-71593", "name": "((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761992" ], "products": [ "species_70113", "species_10762040" ], "modifiers": [ [ "species_10761997", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_113527", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_113527", "P36143", "YKR058W", "YPR184W" ] }, "reaction_10769898": { "compartment": "compartment_70101", "id": "reaction_10769898", "reactome": "R-SCE-428676", "name": "sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203" ], "products": [ "species_428686", "species_428671" ], "modifiers": [ [ "species_10769895", "catalyst" ] ], "additional_components": [ "YDR294C" ] }, "reaction_10787703": { "compartment": "compartment_70101", "id": "reaction_10787703", "reactome": "R-SCE-8955844", "name": "RBKS phosphorylates ribose to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8955853" ], "products": [ "species_29370", "species_73578" ], "modifiers": [ [ "species_10787700", "catalyst" ] ], "additional_components": [ "YCR036W" ] }, "reaction_10773027": { "compartment": "compartment_12045", "id": "reaction_10773027", "reactome": "R-SCE-1482612", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10773044": { "compartment": "compartment_70101", "id": "reaction_10773044", "reactome": "R-SCE-1482656", "name": "PA is hydrolysed to 1-acyl LPA by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_1500604", "species_1524021" ], "modifiers": [ [ "species_10772999", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10766748": { "compartment": "compartment_70101", "id": "reaction_10766748", "reactome": "R-SCE-191382", "name": "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362" ], "products": [ "species_191324" ], "modifiers": [ [ "species_10766745", "catalyst" ] ], "additional_components": [ "P15496", "YPL117C", "species_109496" ] }, "reaction_10773106": { "compartment": "compartment_70616", "id": "reaction_10773106", "reactome": "R-SCE-1482759", "name": "MLCL is hydrolyzed to DLCL by PLA2G4A (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498773", "species_113521" ], "products": [ "species_1524085", "species_1498753" ], "modifiers": [ [ "species_10773103", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10784748": { "compartment": "compartment_876", "id": "reaction_10784748", "reactome": "R-SCE-6809325", "name": "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10784742", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10761813": { "compartment": "compartment_70101", "id": "reaction_10761813", "reactome": "R-SCE-71249", "name": "SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31503" ], "products": [ "species_29424", "species_31311" ], "modifiers": [ [ "species_10761810", "catalyst" ] ], "additional_components": [ "P37292", "YBR263W" ] }, "reaction_10785576": { "compartment": "compartment_528865", "id": "reaction_10785576", "reactome": "R-SCE-8851494", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851509", "species_8851517" ], "products": [ "species_8851518", "species_8851513", "species_5228597" ], "modifiers": [ [ "species_10785573", "catalyst" ] ], "additional_components": [ "species_29494", "species_29438", "species_110614", "species_29420", "species_110096", "species_110094", "P40009", "YER005W", "species_74016" ] }, "reaction_10767509": { "compartment": "compartment_70101", "id": "reaction_10767509", "reactome": "R-SCE-200676", "name": "MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200739" ], "products": [ "species_29366", "species_174404" ], "modifiers": [ [ "species_10767506", "catalyst" ] ], "additional_components": [ "P53128", "YGL125W" ] }, "reaction_10773109": { "compartment": "compartment_12045", "id": "reaction_10773109", "reactome": "R-SCE-1482771", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[9]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_29356" ], "products": [ "species_1498724", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10761833": { "compartment": "compartment_70101", "id": "reaction_10761833", "reactome": "R-SCE-71286", "name": "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_30401" ], "products": [ "species_70106", "species_71285", "species_29916" ], "modifiers": [ [ "species_10761830", "catalyst" ] ], "additional_components": [ "YDR465C" ] }, "reaction_10766996": { "compartment": "compartment_70101", "id": "reaction_10766996", "reactome": "R-SCE-196955", "name": "2xENPP1 hydrolyzes FAD to FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29386", "species_29356" ], "products": [ "species_73524", "species_76577" ], "modifiers": [ [ "species_10766993", "catalyst" ] ], "additional_components": [ "P39997", "YEL016C", "P25353", "YCR026C" ] }, "reaction_10775588": { "compartment": "compartment_70101", "id": "reaction_10775588", "reactome": "R-SCE-3322016", "name": "GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775576" ], "products": [ "species_10775586" ], "modifiers": [ [ "species_10775557", "catalyst" ] ], "additional_components": [ "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "YEL011W" ] }, "reaction_10766523": { "compartment": "compartment_70101", "id": "reaction_10766523", "reactome": "R-SCE-189406", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189464", "species_29356" ], "products": [ "species_189449", "species_31633" ], "modifiers": [ [ "species_10766520", "catalyst" ] ], "additional_components": [ "CHEBI:36319", "P28789", "YDL205C" ] }, "reaction_10775584": { "compartment": "compartment_70101", "id": "reaction_10775584", "reactome": "R-SCE-3322014", "name": "Autoglucosylation of GYG2 complexed with GYS2-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775581" ], "products": [ "species_110096", "species_10775574" ], "modifiers": [ [ "species_10775581", "catalyst" ] ], "additional_components": [ "P27472", "YLR258W", "P47011", "YJL137C", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P27472", "YLR258W", "P47011", "YJL137C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10767006": { "compartment": "compartment_70101", "id": "reaction_10767006", "reactome": "R-SCE-196964", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196931" ], "products": [ "species_29370", "species_73524" ], "modifiers": [ [ "species_10767003", "catalyst" ] ], "additional_components": [ "Q03778", "YDR236C", "species_109496" ] }, "reaction_10773229": { "compartment": "compartment_12045", "id": "reaction_10773229", "reactome": "R-SCE-1482976", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426955", "species_426910" ], "products": [ "species_109395", "species_426639" ], "modifiers": [ [ "species_10773226", "catalyst" ] ], "additional_components": [ "P06197", "YPR113W", "species_113527", "species_109496" ] }, "reaction_10787576": { "compartment": "compartment_984", "id": "reaction_10787576", "reactome": "R-SCE-8952251", "name": "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2173763", "species_109276" ], "products": [ "species_8952253", "species_8954142" ], "modifiers": [ [ "species_10787573", "catalyst" ] ], "additional_components": [ "YDR058C" ] }, "reaction_10761616": { "compartment": "compartment_5460", "id": "reaction_10761616", "reactome": "R-SCE-70724", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_508190" ], "products": [ "species_113552", "species_508181" ], "modifiers": [ [ "species_10761613", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "species_351964", "CHEBI:57762", "CHEBI:28654", "CHEBI:16530", "CHEBI:17865", "P47176", "YJR148W", "P38891", "YHR208W" ] }, "reaction_10778320": { "compartment": "compartment_70101", "id": "reaction_10778320", "reactome": "R-SCE-5652195", "name": "SORD oxidizes D-sorbitol to Fru", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_5652213" ], "products": [ "species_70106", "species_73473", "species_29532" ], "modifiers": [ [ "species_10778317", "catalyst" ] ], "additional_components": [ "Q07993", "YLR070C", "species_158417", "Q07786", "YDL246C", "P35497", "YJR159W" ] }, "reaction_10763347": { "compartment": "compartment_70101", "id": "reaction_10763347", "reactome": "R-SCE-73794", "name": "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29602", "species_29360", "species_29356" ], "products": [ "species_73473", "species_70106", "species_111584" ], "modifiers": [ [ "species_10763342", "catalyst" ], [ "species_10763345", "inhibitor" ], [ "species_111584", "inhibitor" ] ], "additional_components": [ "P38697", "YHR216W", "P50095", "YLR432W", "P50094", "YML056C", "P38697", "YHR216W", "P50095", "YLR432W", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842", "P50094", "YML056C" ] }, "reaction_10788488": { "compartment": "compartment_70101", "id": "reaction_10788488", "reactome": "R-SCE-9034539", "name": "PXLP-K56-SRR dimer deaminates L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_29382", "species_29398", "species_29356" ], "modifiers": [ [ "species_10788216", "catalyst" ] ], "additional_components": [ "P36007", "YKL218C" ] }, "reaction_10784328": { "compartment": "compartment_12045", "id": "reaction_10784328", "reactome": "R-SCE-6807053", "name": "SC5D desaturates LTHSOL to 7-dehydroCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_6807054", "species_29368" ], "products": [ "species_29366", "species_6807057", "species_29356" ], "modifiers": [ [ "species_10766920", "catalyst" ] ], "additional_components": [ "YLR056W" ] }, "reaction_10773042": { "compartment": "compartment_12045", "id": "reaction_10773042", "reactome": "R-SCE-1482646", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10773037", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10764110": { "compartment": "compartment_12045", "id": "reaction_10764110", "reactome": "R-SCE-75885", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500604", "species_1500578" ], "products": [ "species_76194", "species_426755" ], "modifiers": [ [ "species_10764107", "catalyst" ] ], "additional_components": [ "P33333", "YDL052C", "Q08750", "YOR298W", "P38226", "YBR042C" ] }, "reaction_10769889": { "compartment": "compartment_70101", "id": "reaction_10769889", "reactome": "R-SCE-428664", "name": "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428275", "species_29356" ], "products": [ "species_428694", "species_29372" ], "modifiers": [ [ "species_10769886", "catalyst" ] ], "additional_components": [ "P47013", "YJL134W", "P23501", "YKR053C" ] }, "reaction_10766913": { "compartment": "compartment_70101", "id": "reaction_10766913", "reactome": "R-SCE-194698", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194644" ], "products": [ "species_29366", "species_194633" ], "modifiers": [ [ "species_10766910", "catalyst" ] ], "additional_components": [ "YNL280C" ] }, "reaction_10773596": { "compartment": "compartment_20699", "id": "reaction_10773596", "reactome": "R-SCE-1676152", "name": "PI4KB binds to ARF1/3:GTP at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773594", "species_10773521" ], "products": [ "species_10773523" ], "modifiers": [], "additional_components": [ "YNL267W", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996", "P39104", "YNL267W", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10761653": { "compartment": "compartment_5460", "id": "reaction_10761653", "reactome": "R-SCE-70967", "name": "isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29938", "species_113526" ], "products": [ "species_113594", "species_29376", "species_29362", "species_113529" ], "modifiers": [ [ "species_10761650", "catalyst" ], [ "species_113581", "catalyst" ] ], "additional_components": [ "P28241", "YOR136W", "P28834", "IDH1", "species_113527" ] }, "reaction_10774302": { "compartment": "compartment_70101", "id": "reaction_10774302", "reactome": "R-SCE-2408551", "name": "SeMet is converted to AdoSeMet by MAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_5357707", "species_29356" ], "products": [ "species_5357652", "species_111294", "species_29372" ], "modifiers": [ [ "species_10766294", "catalyst" ] ], "additional_components": [ "P19358", "YDR502C", "species_74126", "species_109496", "P10659", "YLR180W" ] }, "reaction_10771159": { "compartment": "compartment_70101", "id": "reaction_10771159", "reactome": "R-SCE-548843", "name": "ACSL3,4 ligate CoA to AA to form AA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_29768", "species_113592" ], "products": [ "species_111294", "species_76577", "species_29356", "species_548819" ], "modifiers": [ [ "species_10771156", "catalyst" ] ], "additional_components": [ "P47912", "YMR246W", "P39002", "YIL009W", "P30624", "YOR317W" ] }, "reaction_10783830": { "compartment": "compartment_12045", "id": "reaction_10783830", "reactome": "R-SCE-6800334", "name": "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6800352", "species_1500578" ], "products": [ "species_76194", "species_76103" ], "modifiers": [ [ "species_10783823", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10773032": { "compartment": "compartment_12045", "id": "reaction_10773032", "reactome": "R-SCE-1482629", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10772937": { "compartment": "compartment_12045", "id": "reaction_10772937", "reactome": "R-SCE-1482539", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498740", "species_1500578" ], "products": [ "species_76194", "species_1483256" ], "modifiers": [ [ "species_10772934", "catalyst" ] ], "additional_components": [ "Q12185", "YDR018C", "P38226", "YBR042C" ] }, "reaction_10764651": { "compartment": "compartment_70101", "id": "reaction_10764651", "reactome": "R-SCE-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_6788782" ], "products": [ "species_113592", "species_6788778" ], "modifiers": [ [ "species_10764648", "catalyst" ] ], "additional_components": [ "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "species_109395", "species_76577", "species_109378", "species_109386", "P26364", "YER170W", "P07170", "YDR226W" ] }, "reaction_10763371": { "compartment": "compartment_70101", "id": "reaction_10763371", "reactome": "R-SCE-73800", "name": "SAICAR => AICAR + Fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111399" ], "products": [ "species_29586", "species_111409" ], "modifiers": [ [ "species_10763368", "catalyst" ] ], "additional_components": [ "Q05911", "YLR359W" ] }, "reaction_10773168": { "compartment": "compartment_12045", "id": "reaction_10773168", "reactome": "R-SCE-1482900", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498740", "species_1524021" ], "modifiers": [ [ "species_10772999", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10766900": { "compartment": "compartment_13231", "id": "reaction_10766900", "reactome": "R-SCE-194674", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194681", "species_194688", "species_194725" ], "products": [ "species_194704", "species_194668" ], "modifiers": [ [ "species_10766897", "catalyst" ] ], "additional_components": [ "YNL280C" ] }, "reaction_10772957": { "compartment": "compartment_12045", "id": "reaction_10772957", "reactome": "R-SCE-1482545", "name": "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_29356" ], "products": [ "species_1524023", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10775612": { "compartment": "compartment_70101", "id": "reaction_10775612", "reactome": "R-SCE-3322041", "name": "Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775533" ], "products": [ "species_10775609", "species_110096" ], "modifiers": [ [ "species_10775533", "catalyst" ], [ "species_30537", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10775536": { "compartment": "compartment_70101", "id": "reaction_10775536", "reactome": "R-SCE-3322003", "name": "Autoglucosylation of GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775531" ], "products": [ "species_110096", "species_10775533" ], "modifiers": [ [ "species_10775531", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P27472", "YLR258W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P27472", "YLR258W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10761781": { "compartment": "compartment_70101", "id": "reaction_10761781", "reactome": "R-SCE-71200", "name": "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_29368", "species_29970" ], "products": [ "species_29366", "species_29356", "species_34351" ], "modifiers": [ [ "species_10761778", "catalyst" ] ], "additional_components": [ "YBL098W" ] }, "reaction_10767519": { "compartment": "compartment_70101", "id": "reaction_10767519", "reactome": "R-SCE-200681", "name": "FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_200665" ], "products": [ "species_29370", "species_174404", "species_29372" ], "modifiers": [ [ "species_10767056", "catalyst" ] ], "additional_components": [ "YOR241W" ] }, "reaction_10761689": { "compartment": "compartment_5460", "id": "reaction_10761689", "reactome": "R-SCE-70982", "name": "Fumarate + H2O <=> (S)-Malate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113588" ], "products": [ "species_113544" ], "modifiers": [ [ "species_10761686", "catalyst" ] ], "additional_components": [ "P08417", "YPL262W" ] }, "reaction_10784728": { "compartment": "compartment_70101", "id": "reaction_10784728", "reactome": "R-SCE-6809254", "name": "MTMR8 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784722", "species_10784724" ], "products": [ "species_10784726" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10769851": { "compartment": "compartment_70101", "id": "reaction_10769851", "reactome": "R-SCE-428214", "name": "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428163", "species_113592" ], "products": [ "species_29370", "species_428275" ], "modifiers": [ [ "species_10769848", "catalyst" ] ], "additional_components": [ "Q12246", "YOR171C", "P47045", "TIM54", "Q06147", "YLR260W" ] }, "reaction_10773157": { "compartment": "compartment_12045", "id": "reaction_10773157", "reactome": "R-SCE-1482884", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10767738": { "compartment": "compartment_876", "id": "reaction_10767738", "reactome": "R-SCE-203613", "name": "depalmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767589" ], "products": [ "species_76168", "species_10767646" ], "modifiers": [ [ "species_10767735", "catalyst" ] ], "additional_components": [ "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_113596", "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_29870", "species_113596", "Q12354", "YLR118C" ] }, "reaction_10763944": { "compartment": "compartment_70101", "id": "reaction_10763944", "reactome": "R-SCE-75125", "name": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500006", "species_29370" ], "products": [ "species_113592", "species_500009" ], "modifiers": [ [ "species_10763053", "catalyst" ] ], "additional_components": [ "species_110096", "species_110094", "CHEBI:58593", "species_109395", "species_109378", "species_109402", "YKL024C" ] }, "reaction_10761637": { "compartment": "compartment_5460", "id": "reaction_10761637", "reactome": "R-SCE-70940", "name": "saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_30176" ], "products": [ "species_113556", "species_113552", "species_29362", "species_113529" ], "modifiers": [ [ "species_10761631", "catalyst" ] ], "additional_components": [ "P38999", "YNR050C" ] }, "reaction_10761851": { "compartment": "compartment_70101", "id": "reaction_10761851", "reactome": "R-SCE-71299", "name": "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_29996" ], "products": [ "species_70106", "species_29732", "species_29364", "species_113528" ], "modifiers": [ [ "species_10761848", "catalyst" ] ], "additional_components": [ "P38720", "YHR183W" ] }, "reaction_10773119": { "compartment": "compartment_70616", "id": "reaction_10773119", "reactome": "R-SCE-1482794", "name": "CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524079", "species_1524072" ], "products": [ "species_1524075", "species_1498773" ], "modifiers": [ [ "species_10773113", "catalyst" ] ], "additional_components": [] }, "reaction_10784773": { "compartment": "compartment_70101", "id": "reaction_10784773", "reactome": "R-SCE-6809778", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6809774", "species_29356" ], "products": [ "species_422529", "species_29372" ], "modifiers": [ [ "species_10784765", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10761717": { "compartment": "compartment_5460", "id": "reaction_10761717", "reactome": "R-SCE-70994", "name": "Succinate <=> Fumarate (with FAD redox reaction on enzyme)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113536" ], "products": [ "species_113588" ], "modifiers": [ [ "species_10761714", "catalyst" ] ], "additional_components": [ "P21801", "YLL041C", "Q00711", "YKL148C", "Q08749", "TIM18", "P33421", "YKL141W", "species_113596" ] }, "reaction_10764120": { "compartment": "compartment_70101", "id": "reaction_10764120", "reactome": "R-SCE-75887", "name": "Conversion of Glycerol to Glycerol-3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116", "species_113592" ], "products": [ "species_29370", "species_76114" ], "modifiers": [ [ "species_10764115", "catalyst" ] ], "additional_components": [ "YHL032C" ] }, "reaction_10763395": { "compartment": "compartment_70101", "id": "reaction_10763395", "reactome": "R-SCE-73828", "name": "adenylosuccinate => adenosine 5'-monophosphate + fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_35141" ], "products": [ "species_29586", "species_76577" ], "modifiers": [ [ "species_10763368", "catalyst" ] ], "additional_components": [ "Q05911", "YLR359W" ] }, "reaction_10767535": { "compartment": "compartment_70101", "id": "reaction_10767535", "reactome": "R-SCE-200735", "name": "SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_197969" ], "products": [ "species_29424", "species_200739" ], "modifiers": [ [ "species_10761810", "catalyst" ] ], "additional_components": [ "P37292", "YBR263W" ] }, "reaction_10773035": { "compartment": "compartment_12045", "id": "reaction_10773035", "reactome": "R-SCE-1482635", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498730", "species_1500578" ], "products": [ "species_76194", "species_1483256" ], "modifiers": [ [ "species_10772934", "catalyst" ] ], "additional_components": [ "Q12185", "YDR018C", "P38226", "YBR042C" ] }, "reaction_10767447": { "compartment": "compartment_70101", "id": "reaction_10767447", "reactome": "R-SCE-200423", "name": "pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767435", "species_113592" ], "products": [ "species_29370", "species_10767442" ], "modifiers": [ [ "species_10767444", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527", "Q00955", "YNR016C", "species_113527", "P34164", "YGL208W", "Q04739", "YER027C", "P32578", "YDR422C", "P12904", "YGL115W", "P38845", "YHR146W", "P06782", "YDR477W", "P53885", "YNL173C" ] }, "reaction_10761230": { "compartment": "compartment_70101", "id": "reaction_10761230", "reactome": "R-SCE-70427", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29548" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10761125", "catalyst" ] ], "additional_components": [ "Q03262", "YMR278W", "species_109496" ] }, "reaction_10773584": { "compartment": "compartment_171062", "id": "reaction_10773584", "reactome": "R-SCE-1676141", "name": "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_1806199", "species_29372" ], "modifiers": [ [ "species_10773463", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10773458": { "compartment": "compartment_876", "id": "reaction_10773458", "reactome": "R-SCE-1675780", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_392417" ], "modifiers": [ [ "species_10773453", "catalyst" ] ], "additional_components": [ "YJL100W" ] }, "reaction_10786908": { "compartment": "compartment_70101", "id": "reaction_10786908", "reactome": "R-SCE-8876789", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6786250", "species_71284" ], "products": [ "species_71285", "species_8876775" ], "modifiers": [ [ "species_10786905", "catalyst" ] ], "additional_components": [ "YNL092W" ] }, "reaction_10767466": { "compartment": "compartment_5460", "id": "reaction_10767466", "reactome": "R-SCE-200474", "name": "NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8938083", "species_113593" ], "products": [ "species_8938090", "species_159450" ], "modifiers": [ [ "species_10767463", "catalyst" ] ], "additional_components": [ "Q06178", "YLR328W", "P53204", "YGR010W", "species_109496" ] }, "reaction_10762169": { "compartment": "compartment_70101", "id": "reaction_10762169", "reactome": "R-SCE-71735", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_113592", "species_29416" ], "products": [ "species_111294", "species_76577", "species_76183" ], "modifiers": [ [ "species_10762166", "catalyst" ] ], "additional_components": [ "P52910", "YLR153C", "Q01574", "YAL054C" ] }, "reaction_10784745": { "compartment": "compartment_876", "id": "reaction_10784745", "reactome": "R-SCE-6809320", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806240", "species_29372" ], "modifiers": [ [ "species_10784742", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10776275": { "compartment": "compartment_70101", "id": "reaction_10776275", "reactome": "R-SCE-3781023", "name": "PPP1R3C binds to glycogen:GYG1:GYS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775552", "species_10776211" ], "products": [ "species_10776273" ], "modifiers": [], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P40036", "YER054C", "Q06216", "YLR273C", "P28006", "YOR178C", "P40187", "YIL045W", "P40036", "YER054C", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10773161": { "compartment": "compartment_12045", "id": "reaction_10773161", "reactome": "R-SCE-1482892", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10767321": { "compartment": "compartment_70101", "id": "reaction_10767321", "reactome": "R-SCE-199803", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10761868", "catalyst" ] ], "additional_components": [ "P46969", "YJL121C", "species_111793" ] }, "reaction_10776271": { "compartment": "compartment_70101", "id": "reaction_10776271", "reactome": "R-SCE-3781018", "name": "EPM2A dimer dephosphorylates phosphoglycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10776268" ], "products": [ "species_10776261", "species_29372" ], "modifiers": [ [ "species_10776268", "catalyst" ] ], "additional_components": [ "P40187", "YIL045W", "P46958", "YJL146W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P46958", "YJL146W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P46958", "YJL146W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10770915": { "compartment": "compartment_70101", "id": "reaction_10770915", "reactome": "R-SCE-453338", "name": "PGYM b dimer:AMP complex <=> PGYM dimer, b form + 2 AMP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770913" ], "products": [ "species_10761929", "species_76577" ], "modifiers": [], "additional_components": [ "P06738", "YPR160W", "species_76577", "P06738", "YPR160W" ] }, "reaction_10781323": { "compartment": "compartment_70101", "id": "reaction_10781323", "reactome": "R-SCE-5694071", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_5694074" ], "products": [ "species_5694130" ], "modifiers": [ [ "species_10781320", "catalyst" ] ], "additional_components": [ "species_158417", "P50107", "YML004C" ] }, "reaction_10773592": { "compartment": "compartment_876", "id": "reaction_10773592", "reactome": "R-SCE-1676149", "name": "PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_202247", "species_29356" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10767316", "catalyst" ] ], "additional_components": [ "YNL128W" ] }, "reaction_10769915": { "compartment": "compartment_984", "id": "reaction_10769915", "reactome": "R-SCE-428690", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419305", "species_109276" ], "products": [ "species_109277", "species_428662" ], "modifiers": [ [ "species_10769912", "catalyst" ] ], "additional_components": [ "Q05521", "YDR284C", "Q04396", "YDR503C" ] }, "reaction_10774502": { "compartment": "compartment_70101", "id": "reaction_10774502", "reactome": "R-SCE-2509827", "name": "ITPA hydrolyses ITP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2509836" ], "products": [ "species_70106", "species_29602", "species_111294" ], "modifiers": [ [ "species_10774499", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P47119", "YJR069C" ] }, "reaction_10773490": { "compartment": "compartment_20699", "id": "reaction_10773490", "reactome": "R-SCE-1675824", "name": "PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806165", "species_29356" ], "products": [ "species_1806217", "species_29372" ], "modifiers": [ [ "species_10773487", "catalyst" ] ], "additional_components": [ "YOL065C" ] }, "reaction_10773049": { "compartment": "compartment_12045", "id": "reaction_10773049", "reactome": "R-SCE-1482685", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10773024", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10781088": { "compartment": "compartment_70101", "id": "reaction_10781088", "reactome": "R-SCE-5692283", "name": "ALD3A1 oxidises 4HPCP to CXPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5692409", "species_29366", "species_29356" ], "products": [ "species_70106", "species_29364", "species_5692433" ], "modifiers": [ [ "species_10781085", "catalyst" ] ], "additional_components": [ "YMR110C" ] }, "reaction_10774505": { "compartment": "compartment_70101", "id": "reaction_10774505", "reactome": "R-SCE-2509831", "name": "ITPA hydrolyses XTP to XMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509848", "species_29356" ], "products": [ "species_70106", "species_111584", "species_111294" ], "modifiers": [ [ "species_10774499", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P47119", "YJR069C" ] }, "reaction_10766958": { "compartment": "compartment_70101", "id": "reaction_10766958", "reactome": "R-SCE-196761", "name": "2xTPK1:Mg2+ phosphorylates THMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196934" ], "products": [ "species_29480", "species_76577" ], "modifiers": [ [ "species_10766955", "catalyst" ] ], "additional_components": [ "P35202", "YOR143C", "species_109496" ] }, "reaction_10784761": { "compartment": "compartment_171062", "id": "reaction_10784761", "reactome": "R-SCE-6809720", "name": "PI3P is dephosphorylated to PI by MTM1:MTMR12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_1806199", "species_29372" ], "modifiers": [ [ "species_10784752", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10764851": { "compartment": "compartment_70101", "id": "reaction_10764851", "reactome": "R-SCE-111524", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29602", "species_29438", "species_29448" ], "products": [ "species_70106", "species_35141", "species_29372", "species_29420" ], "modifiers": [ [ "species_10764848", "catalyst" ], [ "species_29420", "inhibitor" ], [ "species_113578", "inhibitor" ], [ "species_35141", "inhibitor" ], [ "species_30014", "inhibitor" ] ], "additional_components": [ "P80210", "YNL220W", "species_109496" ] }, "reaction_10786559": { "compartment": "compartment_70101", "id": "reaction_10786559", "reactome": "R-SCE-8869627", "name": "NMRK2 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_70106", "species_29370", "species_8869353" ], "modifiers": [ [ "species_10786553", "catalyst" ] ], "additional_components": [ "YNL129W" ] }, "reaction_10761438": { "compartment": "compartment_5460", "id": "reaction_10761438", "reactome": "R-SCE-70542", "name": "glutamate + acetyl CoA => N-acetyl glutamate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113559" ], "products": [ "species_29374", "species_30471" ], "modifiers": [ [ "species_10761435", "catalyst" ], [ "species_374064", "catalyst" ] ], "additional_components": [ "YER069W" ] }, "reaction_10773539": { "compartment": "compartment_171062", "id": "reaction_10773539", "reactome": "R-SCE-1675974", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806180" ], "modifiers": [ [ "species_10773453", "catalyst" ] ], "additional_components": [ "YJL100W" ] }, "reaction_10773138": { "compartment": "compartment_70616", "id": "reaction_10773138", "reactome": "R-SCE-1482847", "name": "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524085", "species_1524047" ], "modifiers": [ [ "species_10773088", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10770921": { "compartment": "compartment_70101", "id": "reaction_10770921", "reactome": "R-SCE-453339", "name": "poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762038", "species_29372" ], "products": [ "species_10770919", "species_29548" ], "modifiers": [ [ "species_10762009", "catalyst" ] ], "additional_components": [ "P47011", "YJL137C", "species_113527", "P47011", "YJL137C", "species_113527", "P06738", "YPR160W" ] }, "reaction_10761311": { "compartment": "compartment_70101", "id": "reaction_10761311", "reactome": "R-SCE-70467", "name": "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_29370", "species_30014" ], "modifiers": [ [ "species_10761308", "catalyst" ], [ "species_30533", "catalyst" ], [ "species_29370", "catalyst" ], [ "species_76577", "catalyst" ], [ "species_113592", "inhibitor" ], [ "species_76190", "inhibitor" ] ], "additional_components": [ "P16861", "YGR240C", "P16862", "YMR205C" ] }, "reaction_10766705": { "compartment": "compartment_70101", "id": "reaction_10766705", "reactome": "R-SCE-191322", "name": "FDPS dimer transfers IPPP to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191324" ], "products": [ "species_191409", "species_111294" ], "modifiers": [ [ "species_10766699", "catalyst" ] ], "additional_components": [ "P08524", "YJL167W", "species_109496" ] }, "reaction_10772005": { "compartment": "compartment_70101", "id": "reaction_10772005", "reactome": "R-SCE-965079", "name": "2xPNPO:2xFMN oxidizes PXAP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965146", "species_29368", "species_29356" ], "products": [ "species_29408", "species_31633", "species_29390" ], "modifiers": [ [ "species_10772000", "catalyst" ] ], "additional_components": [ "species_73524", "P38075", "YBR035C" ] }, "reaction_10764030": { "compartment": "compartment_70101", "id": "reaction_10764030", "reactome": "R-SCE-75849", "name": "Transport of Citrate from Mitochondrial Matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29654", "species_198498" ], "products": [ "species_76190", "species_113544" ], "modifiers": [ [ "species_10764027", "catalyst" ] ], "additional_components": [ "YBR291C" ] }, "reaction_10771299": { "compartment": "compartment_70101", "id": "reaction_10771299", "reactome": "R-SCE-888614", "name": "IDO2 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29500" ], "products": [ "species_33179" ], "modifiers": [ [ "species_10771296", "catalyst" ] ], "additional_components": [ "P47125", "YJR078W", "species_189444" ] }, "reaction_10768921": { "compartment": "compartment_17951", "id": "reaction_10768921", "reactome": "R-SCE-389609", "name": "ALDH3A2-2 oxidizes pristanal to pristanate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389636", "species_192307" ], "products": [ "species_193465", "species_6811612", "species_192305" ], "modifiers": [ [ "species_10768918", "catalyst" ] ], "additional_components": [ "Q04458", "YMR110C" ] }, "reaction_10767051": { "compartment": "compartment_70101", "id": "reaction_10767051", "reactome": "R-SCE-197271", "name": "NADSYN1 hexamer amidates NAAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197256", "species_29472", "species_113592", "species_29356" ], "products": [ "species_29404", "species_111294", "species_29360", "species_76577" ], "modifiers": [ [ "species_10767048", "catalyst" ] ], "additional_components": [ "P38795", "YHR074W" ] }, "reaction_10767059": { "compartment": "compartment_70101", "id": "reaction_10767059", "reactome": "R-SCE-197958", "name": "FPGS-2 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_111355" ], "products": [ "species_29370", "species_197969", "species_29372" ], "modifiers": [ [ "species_10767056", "catalyst" ] ], "additional_components": [ "YOR241W" ] }, "reaction_10763076": { "compartment": "compartment_70101", "id": "reaction_10763076", "reactome": "R-SCE-73577", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_111627", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_29372", "species_111647" ], "modifiers": [ [ "species_10763067", "catalyst" ] ], "additional_components": [ "P07259", "YJL130C", "P03965", "YJR109C" ] }, "reaction_10766605": { "compartment": "compartment_70101", "id": "reaction_10766605", "reactome": "R-SCE-190182", "name": "UROD decarboxylates URO1 to COPRO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190157" ], "products": [ "species_113528", "species_190128" ], "modifiers": [ [ "species_10766550", "catalyst" ] ], "additional_components": [ "P32347", "YDR047W" ] }, "reaction_10766872": { "compartment": "compartment_70101", "id": "reaction_10766872", "reactome": "R-SCE-193961", "name": "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196366" ], "products": [ "species_193092" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10773558": { "compartment": "compartment_172574", "id": "reaction_10773558", "reactome": "R-SCE-1676065", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806289" ], "products": [ "species_1806212", "species_29372" ], "modifiers": [ [ "species_10773463", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10773091": { "compartment": "compartment_70616", "id": "reaction_10773091", "reactome": "R-SCE-1482745", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524085", "species_1524027" ], "modifiers": [ [ "species_10773088", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10784326": { "compartment": "compartment_5460", "id": "reaction_10784326", "reactome": "R-SCE-6806967", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807477", "species_113593" ], "products": [ "species_113548", "species_113600", "species_113581", "species_113529" ], "modifiers": [ [ "species_10784323", "catalyst" ] ], "additional_components": [ "YKL151C" ] }, "reaction_10761600": { "compartment": "compartment_70101", "id": "reaction_10761600", "reactome": "R-SCE-70723", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_508182", "species_29406" ], "products": [ "species_29404", "species_508187" ], "modifiers": [ [ "species_10761597", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "species_351964", "CHEBI:57762", "CHEBI:28654", "CHEBI:16530", "CHEBI:17865", "P38891", "YHR208W" ] }, "reaction_10773166": { "compartment": "compartment_12045", "id": "reaction_10773166", "reactome": "R-SCE-1482897", "name": "PS is hydrolyzed to 2-acyl LPS by PLA2[10]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_29356" ], "products": [ "species_1498722", "species_1524021" ], "modifiers": [ [ "species_10773124", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10763142": { "compartment": "compartment_70101", "id": "reaction_10763142", "reactome": "R-SCE-73605", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109382", "species_111355" ], "products": [ "species_109366", "species_73604" ], "modifiers": [ [ "species_10763139", "catalyst" ] ], "additional_components": [ "P06785", "YOR074C", "species_109496" ] }, "reaction_10767724": { "compartment": "compartment_20699", "id": "reaction_10767724", "reactome": "R-SCE-203567", "name": "palmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767644", "species_200993" ], "products": [ "species_10767716" ], "modifiers": [ [ "species_10767721", "catalyst" ] ], "additional_components": [ "YHR042W", "YHR042W", "YLR246W" ] }, "reaction_10767524": { "compartment": "compartment_5460", "id": "reaction_10767524", "reactome": "R-SCE-200682", "name": "Mitochondrial FPGS-1 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_200671", "species_113593" ], "products": [ "species_113548", "species_200679", "species_113581" ], "modifiers": [ [ "species_10767521", "catalyst" ] ], "additional_components": [ "YOR241W" ] }, "reaction_10763403": { "compartment": "compartment_5460", "id": "reaction_10763403", "reactome": "R-SCE-73918", "name": "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73871", "species_113559" ], "products": [ "species_29374", "species_73917" ], "modifiers": [ [ "species_10763400", "catalyst" ] ], "additional_components": [ "YML126C" ] }, "reaction_10785542": { "compartment": "compartment_984", "id": "reaction_10785542", "reactome": "R-SCE-8851110", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785539", "catalyst" ] ], "additional_components": [ "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10773526": { "compartment": "compartment_20699", "id": "reaction_10773526", "reactome": "R-SCE-1675883", "name": "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10773523", "catalyst" ] ], "additional_components": [ "P39104", "YNL267W", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10770990": { "compartment": "compartment_70101", "id": "reaction_10770990", "reactome": "R-SCE-482619", "name": "(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_482627", "species_113592" ], "products": [ "species_29370", "species_482625" ], "modifiers": [ [ "species_10770987", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:60471", "CHEBI:58369", "CHEBI:58595", "CHEBI:57667", "species_110096", "species_110094", "CHEBI:58593", "species_29494", "species_500739", "species_29892", "species_110644", "species_30185", "species_30187", "species_29438", "species_110614", "P36010", "YKL067W" ] }, "reaction_10769859": { "compartment": "compartment_70101", "id": "reaction_10769859", "reactome": "R-SCE-428262", "name": "phytoceramide + H2O => stearate + phytosphingosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025544", "species_29356" ], "products": [ "species_3632878", "species_428237" ], "modifiers": [ [ "species_10769856", "catalyst" ] ], "additional_components": [ "YPL087W" ] }, "reaction_10776266": { "compartment": "compartment_70101", "id": "reaction_10776266", "reactome": "R-SCE-3781011", "name": "EPM2A dimer dephosphorylates phosphoglycogen-GYG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10776263" ], "products": [ "species_10776227", "species_29372" ], "modifiers": [ [ "species_10776263", "catalyst" ] ], "additional_components": [ "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10767041": { "compartment": "compartment_70101", "id": "reaction_10767041", "reactome": "R-SCE-197268", "name": "QPRT transfers PRIB to QUIN to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73566", "species_197238" ], "products": [ "species_113528", "species_111294", "species_197220" ], "modifiers": [ [ "species_10767038", "catalyst" ] ], "additional_components": [ "YFR047C" ] }, "reaction_10785578": { "compartment": "compartment_984", "id": "reaction_10785578", "reactome": "R-SCE-8851538", "name": "NTPDase8 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9726184", "species_109276" ], "products": [ "species_9726189", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785532", "catalyst" ] ], "additional_components": [ "species_29494", "species_30187", "species_113592", "species_2509836", "species_29438", "species_110614", "species_29420", "CHEBI:58369", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10774297": { "compartment": "compartment_5460", "id": "reaction_10774297", "reactome": "R-SCE-2395512", "name": "FDXR transfers electrons to FDX1,2 (FDX1L)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774293", "species_10772859" ], "products": [ "species_10772851", "species_10774295", "species_113529" ], "modifiers": [], "additional_components": [ "P48360", "YDR376W", "species_31649", "CHEBI:33737", "Q12184", "YPL252C", "CHEBI:33738", "Q12184", "YPL252C", "P48360", "YDR376W", "species_113596" ] }, "reaction_10771310": { "compartment": "compartment_70101", "id": "reaction_10771310", "reactome": "R-SCE-893593", "name": "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29502", "species_29398" ], "products": [ "species_893599", "species_29432" ], "modifiers": [ [ "species_10771307", "catalyst" ] ], "additional_components": [ "P47039", "YJL060W" ] }, "reaction_10781200": { "compartment": "compartment_70101", "id": "reaction_10781200", "reactome": "R-SCE-5693390", "name": "HSD17B11 dehydrogenates EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_193132" ], "products": [ "species_70106", "species_29364", "species_193066" ], "modifiers": [ [ "species_10781197", "catalyst" ] ], "additional_components": [ "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C" ] }, "reaction_10773448": { "compartment": "compartment_876", "id": "reaction_10773448", "reactome": "R-SCE-1675776", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806240" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10773445", "catalyst" ] ], "additional_components": [ "P38994", "YDR208W" ] }, "reaction_10787145": { "compartment": "compartment_70101", "id": "reaction_10787145", "reactome": "R-SCE-8939959", "name": "NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869353" ], "products": [ "species_111294", "species_29360" ], "modifiers": [ [ "species_10767030", "catalyst" ] ], "additional_components": [ "Q06178", "YLR328W", "P53204", "YGR010W", "species_109496" ] }, "reaction_10788787": { "compartment": "compartment_70101", "id": "reaction_10788787", "reactome": "R-SCE-9638127", "name": "PGM1:Mg2+ isomerises G6P to G1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537" ], "products": [ "species_29548" ], "modifiers": [ [ "species_10788782", "catalyst" ] ], "additional_components": [ "P33401", "YKL127W", "species_109496" ] }, "reaction_10784736": { "compartment": "compartment_17951", "id": "reaction_10784736", "reactome": "R-SCE-6809287", "name": "NUDT12 hydrolyses NADH to NMNH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389620", "species_141343", "species_192305" ], "products": [ "species_6809289", "species_193465" ], "modifiers": [ [ "species_10784733", "catalyst" ] ], "additional_components": [ "YGL067W" ] }, "reaction_10767473": { "compartment": "compartment_7660", "id": "reaction_10767473", "reactome": "R-SCE-200512", "name": "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_200492" ], "products": [ "species_200499", "species_113541" ], "modifiers": [ [ "species_10767470", "catalyst" ] ], "additional_components": [ "species_158417", "Q06178", "YLR328W" ] }, "reaction_10773601": { "compartment": "compartment_876", "id": "reaction_10773601", "reactome": "R-SCE-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10773598", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "P50942", "YNL106C" ] }, "reaction_10774843": { "compartment": "compartment_70101", "id": "reaction_10774843", "reactome": "R-SCE-2993814", "name": "HLCS biotinylates ACACA:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_113592", "species_10774841" ], "products": [ "species_10764051", "species_111294", "species_76577" ], "modifiers": [ [ "species_10774830", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527", "P32874", "YMR207C", "Q00955", "YNR016C", "species_113527", "P32874", "YMR207C", "YDL141W" ] }, "reaction_10771961": { "compartment": "compartment_70101", "id": "reaction_10771961", "reactome": "R-SCE-947514", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_10771945" ], "products": [ "species_10771950", "species_29432" ], "modifiers": [ [ "species_10771958", "catalyst" ] ], "additional_components": [ "species_158417", "P38820", "YHR111W", "species_158417", "P38820", "YHR111W", "P25374", "YCL017C" ] }, "reaction_10773561": { "compartment": "compartment_876", "id": "reaction_10773561", "reactome": "R-SCE-1676082", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10773418", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10774121": { "compartment": "compartment_17951", "id": "reaction_10774121", "reactome": "R-SCE-2066779", "name": "Conversion of DHA-CoA to docosahexaenoic acid (DHA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_2066765" ], "products": [ "species_193514", "species_2066763" ], "modifiers": [ [ "species_10766854", "catalyst" ] ], "additional_components": [ "YJR019C" ] }, "reaction_10773542": { "compartment": "compartment_876", "id": "reaction_10773542", "reactome": "R-SCE-1675988", "name": "PI4P is dephosphorylated to PI by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_392417" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10773511", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "Q08227", "YOL065C", "P50942", "YNL106C" ] }, "reaction_10762104": { "compartment": "compartment_70101", "id": "reaction_10762104", "reactome": "R-SCE-71691", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29510", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_29416" ], "modifiers": [ [ "species_10762101", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10769022": { "compartment": "compartment_17951", "id": "reaction_10769022", "reactome": "R-SCE-389862", "name": "Conversion of glyoxylate to oxalate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389678", "species_141343", "species_113535" ], "products": [ "species_389819", "species_113575" ], "modifiers": [ [ "species_10769016", "catalyst" ] ], "additional_components": [ "species_73524", "P00175", "CYB2" ] }, "reaction_10767564": { "compartment": "compartment_70101", "id": "reaction_10767564", "reactome": "R-SCE-201035", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_3632881", "species_113592" ], "products": [ "species_111294", "species_76577", "species_29356", "species_200993" ], "modifiers": [ [ "species_10767561", "catalyst" ] ], "additional_components": [ "P47912", "YMR246W", "P39002", "YIL009W", "P30624", "YOR317W", "P39518", "YER015W" ] }, "reaction_10761112": { "compartment": "compartment_70101", "id": "reaction_10761112", "reactome": "R-SCE-70262", "name": "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30533", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10761109", "catalyst" ] ], "additional_components": [ "P32604", "YJL155C" ] }, "reaction_10768062": { "compartment": "compartment_70101", "id": "reaction_10768062", "reactome": "R-SCE-209792", "name": "N-acetylation of serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183", "species_209914" ], "products": [ "species_76194", "species_209793" ], "modifiers": [ [ "species_10768059", "catalyst" ] ], "additional_components": [ "YDR071C" ] }, "reaction_10774508": { "compartment": "compartment_70101", "id": "reaction_10774508", "reactome": "R-SCE-2509838", "name": "ITPA hydrolyses dITP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509835", "species_29356" ], "products": [ "species_70106", "species_9731659", "species_111294" ], "modifiers": [ [ "species_10774499", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P47119", "YJR069C" ] }, "reaction_10785581": { "compartment": "compartment_984", "id": "reaction_10785581", "reactome": "R-SCE-8851550", "name": "NTPDase8 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9726189", "species_109276" ], "products": [ "species_109277", "species_351626", "species_9726186" ], "modifiers": [ [ "species_10785532", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58369", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "species_109366", "species_109395", "species_29602", "species_76577", "species_109402", "species_113578", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10761792": { "compartment": "compartment_70101", "id": "reaction_10761792", "reactome": "R-SCE-71217", "name": "3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_34351" ], "products": [ "species_30487", "species_29432" ], "modifiers": [ [ "species_10761789", "catalyst" ] ], "additional_components": [ "Q05979", "YLR231C" ] }, "reaction_10763309": { "compartment": "compartment_70101", "id": "reaction_10763309", "reactome": "R-SCE-73788", "name": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500071", "species_113592" ], "products": [ "species_500077", "species_29370" ], "modifiers": [ [ "species_10763306", "catalyst" ] ], "additional_components": [ "CHEBI:57673", "species_113578", "species_29420", "CHEBI:58595", "YDR454C" ] }, "reaction_10766758": { "compartment": "compartment_70101", "id": "reaction_10766758", "reactome": "R-SCE-191402", "name": "Reduction of presqualene diphosphate to form squalene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_191265", "species_29364" ], "products": [ "species_29366", "species_191269", "species_111294" ], "modifiers": [ [ "species_10766755", "catalyst" ] ], "additional_components": [ "P29704", "YHR190W", "species_109496" ] }, "reaction_10766487": { "compartment": "compartment_5460", "id": "reaction_10766487", "reactome": "R-SCE-188467", "name": "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_188458" ], "products": [ "species_188451", "species_31649" ], "modifiers": [ [ "species_10766484", "catalyst" ] ], "additional_components": [ "YIL155C" ] }, "reaction_10781600": { "compartment": "compartment_70101", "id": "reaction_10781600", "reactome": "R-SCE-5694583", "name": "ABHD4 hydrolyses NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694568" ], "products": [ "species_5694580", "species_5694567" ], "modifiers": [ [ "species_10781597", "catalyst" ] ], "additional_components": [ "Q12385", "YLR099C", "Q04623", "YDR125C", "P53264", "YGR110W", "P53208", "YGR015C" ] }, "reaction_10773609": { "compartment": "compartment_876", "id": "reaction_10773609", "reactome": "R-SCE-1676203", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806240", "species_29372" ], "modifiers": [ [ "species_10773550", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "P47147", "YJR110W", "P50942", "YNL106C" ] }, "reaction_10764056": { "compartment": "compartment_70101", "id": "reaction_10764056", "reactome": "R-SCE-75851", "name": "Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10764053", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527", "P32874", "YMR207C" ] }, "reaction_10771185": { "compartment": "compartment_70101", "id": "reaction_10771185", "reactome": "R-SCE-549192", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76103", "species_75967" ], "products": [ "species_76194", "species_549167" ], "modifiers": [ [ "species_10771182", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10763172": { "compartment": "compartment_7660", "id": "reaction_10763172", "reactome": "R-SCE-73666", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_500739" ], "products": [ "species_113541", "species_500742", "species_9668967" ], "modifiers": [ [ "species_10763169", "catalyst" ] ], "additional_components": [ "P33317", "YBR252W" ] }, "reaction_10761773": { "compartment": "compartment_70101", "id": "reaction_10761773", "reactome": "R-SCE-71146", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71112" ], "products": [ "species_29356", "species_71129" ], "modifiers": [ [ "species_10761770", "catalyst" ] ], "additional_components": [ "P38744", "YHL018W" ] }, "reaction_10773002": { "compartment": "compartment_17906", "id": "reaction_10773002", "reactome": "R-SCE-1482604", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590", "species_29356" ], "products": [ "species_1524103", "species_1500580" ], "modifiers": [ [ "species_10772999", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10764827": { "compartment": "compartment_70101", "id": "reaction_10764827", "reactome": "R-SCE-111215", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_110644" ], "products": [ "species_73566", "species_109386" ], "modifiers": [ [ "species_10763105", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_29372", "catalyst" ] ], "additional_components": [ "P38063", "YBL068W", "P32895", "YKL181W", "P38689", "YHL011C", "Q12265", "YOL061W", "P38620", "YER099C" ] }, "reaction_10774851": { "compartment": "compartment_5460", "id": "reaction_10774851", "reactome": "R-SCE-2995330", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_2162257", "species_189444" ], "products": [ "species_2995328", "species_159450" ], "modifiers": [ [ "species_10774848", "catalyst" ] ], "additional_components": [ "YPL172C" ] }, "reaction_10761624": { "compartment": "compartment_5460", "id": "reaction_10761624", "reactome": "R-SCE-70881", "name": "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71847", "species_113521" ], "products": [ "species_29374", "species_573404" ], "modifiers": [ [ "species_10761621", "catalyst" ] ], "additional_components": [ "YDR036C" ] }, "reaction_10767280": { "compartment": "compartment_70101", "id": "reaction_10767280", "reactome": "R-SCE-198824", "name": "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10767267" ], "products": [ "species_29360", "species_10767269" ], "modifiers": [ [ "species_10767277", "catalyst" ] ], "additional_components": [ "CHEBI:36144", "P40312", "YNL111C", "species_189444", "P40312", "YNL111C", "P38626", "YIL043C", "species_113596" ] }, "reaction_10785569": { "compartment": "compartment_984", "id": "reaction_10785569", "reactome": "R-SCE-8851396", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851462", "species_109276" ], "products": [ "species_109277", "species_351626", "species_8851461" ], "modifiers": [ [ "species_10785566", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58280", "species_110094", "species_110096", "species_109395", "species_29602", "species_109402", "species_113578", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10774119": { "compartment": "compartment_17951", "id": "reaction_10774119", "reactome": "R-SCE-2066778", "name": "Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2066767", "species_141343" ], "products": [ "species_2066766" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10787695": { "compartment": "compartment_5460", "id": "reaction_10787695", "reactome": "R-SCE-8955817", "name": "PRODH2 oxidises HPRO to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784215", "species_113597" ], "products": [ "species_164934", "species_113521", "species_113590" ], "modifiers": [ [ "species_10781897", "catalyst" ] ], "additional_components": [ "YLR142W" ] }, "reaction_10772003": { "compartment": "compartment_70101", "id": "reaction_10772003", "reactome": "R-SCE-965019", "name": "2xPNPO:2xFMN oxidizes PDXP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964952", "species_29368" ], "products": [ "species_29408", "species_29390" ], "modifiers": [ [ "species_10772000", "catalyst" ] ], "additional_components": [ "species_73524", "P38075", "YBR035C" ] }, "reaction_10771152": { "compartment": "compartment_70101", "id": "reaction_10771152", "reactome": "R-SCE-548831", "name": "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_548809" ], "products": [ "species_29366", "species_428139" ], "modifiers": [ [ "species_10771147", "catalyst" ] ], "additional_components": [ "YDL015C" ] }, "reaction_10761763": { "compartment": "compartment_5460", "id": "reaction_10761763", "reactome": "R-SCE-71037", "name": "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113526", "species_70951" ], "products": [ "species_70955", "species_29376", "species_29362" ], "modifiers": [ [ "species_10761760", "catalyst" ] ], "additional_components": [ "species_29480", "P20967", "YIL125W", "CHEBI:17460", "P09624", "YFL018C", "species_113596", "P19262", "YDR148C" ] }, "reaction_10767016": { "compartment": "compartment_70101", "id": "reaction_10767016", "reactome": "R-SCE-197198", "name": "NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29360" ], "products": [ "species_29370", "species_29366" ], "modifiers": [ [ "species_10767013", "catalyst" ] ], "additional_components": [ "species_158417", "P21373", "YJR049C" ] }, "reaction_10784758": { "compartment": "compartment_70101", "id": "reaction_10784758", "reactome": "R-SCE-6809707", "name": "MTMR12 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784750", "species_10773465" ], "products": [ "species_10784756" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10782032": { "compartment": "compartment_7660", "id": "reaction_10782032", "reactome": "R-SCE-6788810", "name": "AK6 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788813", "species_29358" ], "products": [ "species_113582", "species_6788807" ], "modifiers": [ [ "species_10782029", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "YDL166C" ] }, "reaction_10768262": { "compartment": "compartment_70101", "id": "reaction_10768262", "reactome": "R-SCE-266072", "name": "LTA4 is hydolysed to LTB4 by LTA4H", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265281", "species_29356" ], "products": [ "species_266056" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10787954": { "compartment": "compartment_5460", "id": "reaction_10787954", "reactome": "R-SCE-9012016", "name": "FAHD1:Zn2+ dimer hydrolyses OA to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587" ], "products": [ "species_29376", "species_113557" ], "modifiers": [ [ "species_10787951", "catalyst" ] ], "additional_components": [ "P53889", "YNL168C", "species_109496" ] }, "reaction_10784681": { "compartment": "compartment_70101", "id": "reaction_10784681", "reactome": "R-SCE-6808496", "name": "ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_111353", "species_29356" ], "products": [ "species_70106", "species_29364", "species_113528", "species_197969" ], "modifiers": [ [ "species_10784678", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10784137": { "compartment": "compartment_5460", "id": "reaction_10784137", "reactome": "R-SCE-6801328", "name": "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693984", "species_113526" ], "products": [ "species_6801458", "species_29362" ], "modifiers": [ [ "species_10784132", "catalyst" ] ], "additional_components": [ "YBR084W" ] }, "reaction_10763379": { "compartment": "compartment_70101", "id": "reaction_10763379", "reactome": "R-SCE-73810", "name": "FGAM + ATP => AIR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111369" ], "products": [ "species_70106", "species_29370", "species_111370", "species_29372" ], "modifiers": [ [ "species_10763376", "catalyst" ] ], "additional_components": [ "YGL234W" ] }, "reaction_10771277": { "compartment": "compartment_5460", "id": "reaction_10771277", "reactome": "R-SCE-880007", "name": "(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_879997" ], "products": [ "species_113594", "species_31649" ], "modifiers": [ [ "species_10771274", "catalyst" ], [ "species_880069", "catalyst" ], [ "species_113527", "catalyst" ], [ "species_880067", "catalyst" ] ], "additional_components": [ "YDL178W" ] }, "reaction_10766543": { "compartment": "compartment_17927", "id": "reaction_10766543", "reactome": "R-SCE-189423", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189478" ], "products": [ "species_189481", "species_189463" ], "modifiers": [ [ "species_10766540", "catalyst" ] ], "additional_components": [ "P40012", "YER014W", "species_113596" ] }, "reaction_10773316": { "compartment": "compartment_12045", "id": "reaction_10773316", "reactome": "R-SCE-1483190", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_428686" ], "products": [ "species_111294", "species_1500603" ], "modifiers": [ [ "species_10773313", "catalyst" ] ], "additional_components": [ "P33412", "YGR007W" ] }, "reaction_10773052": { "compartment": "compartment_70616", "id": "reaction_10773052", "reactome": "R-SCE-1482689", "name": "1-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524027", "species_1524038" ], "products": [ "species_1524042", "species_29374" ], "modifiers": [ [ "species_10772962", "catalyst" ] ], "additional_components": [ "YDL142C" ] }, "reaction_10768252": { "compartment": "compartment_876", "id": "reaction_10768252", "reactome": "R-SCE-266070", "name": "LTC4 is exported from the cytosol by ABCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266066" ], "products": [ "species_266013" ], "modifiers": [ [ "species_10768249", "catalyst" ] ], "additional_components": [ "YDR135C" ] }, "reaction_10761148": { "compartment": "compartment_70101", "id": "reaction_10761148", "reactome": "R-SCE-70349", "name": "DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_30393" ], "products": [ "species_29370", "species_29578" ], "modifiers": [ [ "species_10761145", "catalyst" ] ], "additional_components": [ "P54838", "YML070W", "species_109496" ] }, "reaction_10766599": { "compartment": "compartment_70101", "id": "reaction_10766599", "reactome": "R-SCE-189488", "name": "UROS transforms HMB to URO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189449" ], "products": [ "species_189407", "species_29356" ], "modifiers": [ [ "species_10766596", "catalyst" ] ], "additional_components": [ "YOR278W" ] }, "reaction_10773148": { "compartment": "compartment_12045", "id": "reaction_10773148", "reactome": "R-SCE-1482861", "name": "MLCL is acylated to CL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524069", "species_1500578" ], "products": [ "species_76194", "species_1524081" ], "modifiers": [ [ "species_10764105", "catalyst" ] ], "additional_components": [ "YBR042C" ] }, "reaction_10784649": { "compartment": "compartment_13977", "id": "reaction_10784649", "reactome": "R-SCE-6808464", "name": "ALDH3B2 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_29356", "species_6808468" ], "products": [ "species_70106", "species_73473", "species_2453691" ], "modifiers": [ [ "species_10784646", "catalyst" ] ], "additional_components": [ "YMR110C" ] }, "reaction_10773056": { "compartment": "compartment_12045", "id": "reaction_10773056", "reactome": "R-SCE-1482696", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10764653": { "compartment": "compartment_70101", "id": "reaction_10764653", "reactome": "R-SCE-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6788778" ], "products": [ "species_29370", "species_6788782" ], "modifiers": [ [ "species_10764648", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "P26364", "YER170W", "P07170", "YDR226W" ] }, "reaction_10787680": { "compartment": "compartment_70101", "id": "reaction_10787680", "reactome": "R-SCE-8954327", "name": "UCKL1 phosphorylates urindine, cytidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500759", "species_113592" ], "products": [ "species_29370", "species_500761" ], "modifiers": [ [ "species_10787677", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:16704", "species_109395", "species_109402", "YNR012W" ] }, "reaction_10762000": { "compartment": "compartment_70101", "id": "reaction_10762000", "reactome": "R-SCE-71552", "name": "limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10761969" ], "products": [ "species_10761992" ], "modifiers": [ [ "species_10761997", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_113527", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_113527", "P36143", "YKR058W", "YPR184W" ] }, "reaction_10776278": { "compartment": "compartment_70101", "id": "reaction_10776278", "reactome": "R-SCE-3781024", "name": "GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10776273" ], "products": [ "species_10776259", "species_109402" ], "modifiers": [ [ "species_10776273", "catalyst" ] ], "additional_components": [ "P40187", "YIL045W", "P40036", "YER054C", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P46958", "YJL146W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W", "P40187", "YIL045W", "P40036", "YER054C", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "Q12096", "YOR320C", "P28006", "YOR178C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10787833": { "compartment": "compartment_70101", "id": "reaction_10787833", "reactome": "R-SCE-8982667", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787326" ], "products": [ "species_6787328" ], "modifiers": [ [ "species_10761119", "catalyst" ] ], "additional_components": [ "Q03262", "YMR278W", "species_109496" ] }, "reaction_10788340": { "compartment": "compartment_70101", "id": "reaction_10788340", "reactome": "R-SCE-9018862", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9022655" ], "products": [ "species_9022660" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10773563": { "compartment": "compartment_171062", "id": "reaction_10773563", "reactome": "R-SCE-1676105", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806205", "species_29356" ], "products": [ "species_1806259", "species_29372" ], "modifiers": [ [ "species_10773463", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10774859": { "compartment": "compartment_5460", "id": "reaction_10774859", "reactome": "R-SCE-2995334", "name": "COX15 transforms heme O to heme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2995328" ], "products": [ "species_2995348" ], "modifiers": [ [ "species_10774856", "catalyst" ] ], "additional_components": [ "YER141W" ] }, "reaction_10781907": { "compartment": "compartment_5460", "id": "reaction_10781907", "reactome": "R-SCE-6784393", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587", "species_6784236" ], "products": [ "species_6784229", "species_113553" ], "modifiers": [ [ "species_10761497", "catalyst" ] ], "additional_components": [ "Q01802", "YKL106W" ] }, "reaction_10773380": { "compartment": "compartment_70101", "id": "reaction_10773380", "reactome": "R-SCE-1614524", "name": "PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369", "species_200736" ], "products": [ "species_1614518", "species_29356" ], "modifiers": [ [ "species_10773377", "catalyst" ] ], "additional_components": [ "P32582", "YGR155W", "species_189444" ] }, "reaction_10775560": { "compartment": "compartment_70101", "id": "reaction_10775560", "reactome": "R-SCE-3322005", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775513" ], "products": [ "species_10775552" ], "modifiers": [ [ "species_10775557", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "YEL011W" ] }, "reaction_10782009": { "compartment": "compartment_70101", "id": "reaction_10782009", "reactome": "R-SCE-6788295", "name": "HDHD1:Mg2+ dephosphorylates PURIDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788291", "species_29356" ], "products": [ "species_29372", "species_6788290" ], "modifiers": [ [ "species_10782006", "catalyst" ] ], "additional_components": [ "Q86ZR7", "YKL033W-A", "species_109496" ] }, "reaction_10781636": { "compartment": "compartment_12045", "id": "reaction_10781636", "reactome": "R-SCE-5696424", "name": "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696426", "species_192172" ], "products": [ "species_162743", "species_5696412" ], "modifiers": [ [ "species_10781633", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10771046": { "compartment": "compartment_876", "id": "reaction_10771046", "reactome": "R-SCE-499981", "name": "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10771043", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10782630": { "compartment": "compartment_5460", "id": "reaction_10782630", "reactome": "R-SCE-6793591", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6793610", "species_10782620", "species_2162265" ], "products": [ "species_10781283", "species_6793613", "species_379705" ], "modifiers": [ [ "species_10782627", "catalyst" ] ], "additional_components": [ "YAL044C", "YAL044C", "CHEBI:49883", "P32875", "YOR196C" ] }, "reaction_10769056": { "compartment": "compartment_17951", "id": "reaction_10769056", "reactome": "R-SCE-390252", "name": "HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390249", "species_141343" ], "products": [ "species_390248" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10772015": { "compartment": "compartment_70101", "id": "reaction_10772015", "reactome": "R-SCE-977324", "name": "PSPH:Mg2+ dimer dephosphorylates O-P-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_936706" ], "products": [ "species_200736", "species_29372" ], "modifiers": [ [ "species_10772012", "catalyst" ] ], "additional_components": [ "P42941", "YGR208W", "species_109496" ] }, "reaction_10766979": { "compartment": "compartment_70101", "id": "reaction_10766979", "reactome": "R-SCE-196929", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73524", "species_113592" ], "products": [ "species_29386", "species_111294" ], "modifiers": [ [ "species_10766976", "catalyst" ] ], "additional_components": [ "YDL045C" ] }, "reaction_10781999": { "compartment": "compartment_17951", "id": "reaction_10781999", "reactome": "R-SCE-6787811", "name": "HAO2 tetramer oxidises 2OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787810", "species_113535" ], "products": [ "species_6787814", "species_113575" ], "modifiers": [ [ "species_10781996", "catalyst" ] ], "additional_components": [ "P00175", "CYB2" ] }, "reaction_10761476": { "compartment": "compartment_70101", "id": "reaction_10761476", "reactome": "R-SCE-70573", "name": "argininosuccinate <=> fumarate + arginine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_34575" ], "products": [ "species_29586", "species_29468" ], "modifiers": [ [ "species_10761473", "catalyst" ] ], "additional_components": [ "P04076", "YHR018C" ] }, "reaction_10766690": { "compartment": "compartment_70101", "id": "reaction_10766690", "reactome": "R-SCE-191299", "name": "Squalene is oxidized to its epoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191269", "species_29368" ], "products": [ "species_29366", "species_191309", "species_29356" ], "modifiers": [ [ "species_10766687", "catalyst" ] ], "additional_components": [ "P32476", "YGR175C", "species_113596" ] }, "reaction_10761732": { "compartment": "compartment_5460", "id": "reaction_10761732", "reactome": "R-SCE-70997", "name": "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_70958" ], "products": [ "species_29374", "species_113536", "species_113593" ], "modifiers": [ [ "species_10761729", "catalyst" ] ], "additional_components": [ "P53598", "YOR142W", "P53312", "YGR244C" ] }, "reaction_10786830": { "compartment": "compartment_17927", "id": "reaction_10786830", "reactome": "R-SCE-8875838", "name": "SLC25A19 transports ThDP from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29480" ], "products": [ "species_8878387" ], "modifiers": [ [ "species_10786827", "catalyst" ] ], "additional_components": [ "YGR096W" ] }, "reaction_10765677": { "compartment": "compartment_70101", "id": "reaction_10765677", "reactome": "R-SCE-163764", "name": "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29878", "species_29512" ], "products": [ "species_29578", "species_29882" ], "modifiers": [ [ "species_10761886", "catalyst" ] ], "additional_components": [ "P15019", "YLR354C" ] }, "reaction_10767455": { "compartment": "compartment_17927", "id": "reaction_10767455", "reactome": "R-SCE-200424", "name": "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_201023", "species_201034" ], "products": [ "species_549207", "species_201050" ], "modifiers": [ [ "species_10767452", "catalyst" ] ], "additional_components": [ "YOR100C" ] }, "reaction_10763358": { "compartment": "compartment_70101", "id": "reaction_10763358", "reactome": "R-SCE-73797", "name": "FAICAR => IMP + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111427" ], "products": [ "species_29602", "species_29356" ], "modifiers": [ [ "species_10763355", "catalyst" ] ], "additional_components": [ "P38009", "YMR120C" ] }, "reaction_10773353": { "compartment": "compartment_70101", "id": "reaction_10773353", "reactome": "R-SCE-1497810", "name": "Uncoupled eNOS favours the formation of superoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29368" ], "products": [ "species_29366", "species_1222424" ], "modifiers": [ [ "species_10773348", "catalyst" ] ], "additional_components": [ "P06787", "YBR109C", "species_158417", "P12688", "YKL126W", "P02829", "YPL240C", "species_73524", "species_74016", "species_189444", "P16603", "YHR042W", "species_1497857", "species_29870", "P15108", "YMR186W", "species_113596", "P11792", "YHR205W" ] }, "reaction_10788219": { "compartment": "compartment_70101", "id": "reaction_10788219", "reactome": "R-SCE-9014741", "name": "PXLP-K56-SRR dimer deaminates D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_376186" ], "products": [ "species_29382", "species_29398", "species_29356" ], "modifiers": [ [ "species_10788216", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "P36007", "YKL218C" ] }, "reaction_10786160": { "compartment": "compartment_12045", "id": "reaction_10786160", "reactome": "R-SCE-8857686", "name": "FITM1, FITM2 bind TAGs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786156", "species_549167" ], "products": [ "species_10786158" ], "modifiers": [], "additional_components": [ "Q06676", "YDR319C", "P53012", "YGL126W", "species_549167", "Q06676", "YDR319C", "P53012", "YGL126W" ] }, "reaction_10767260": { "compartment": "compartment_876", "id": "reaction_10767260", "reactome": "R-SCE-198818", "name": "SLC2A1,3 transports DeHA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198852" ], "products": [ "species_198827" ], "modifiers": [ [ "species_10767257", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10762137": { "compartment": "compartment_5460", "id": "reaction_10762137", "reactome": "R-SCE-71723", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_113532" ], "products": [ "species_113539", "species_29362", "species_113529" ], "modifiers": [ [ "species_10762134", "catalyst" ] ], "additional_components": [ "P40047", "YER073W" ] }, "reaction_10763070": { "compartment": "compartment_70101", "id": "reaction_10763070", "reactome": "R-SCE-73571", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_111628" ], "products": [ "species_29356", "species_76630" ], "modifiers": [ [ "species_10763067", "catalyst" ] ], "additional_components": [ "P07259", "YJL130C", "P03965", "YJR109C" ] }, "reaction_10769862": { "compartment": "compartment_70101", "id": "reaction_10769862", "reactome": "R-SCE-428273", "name": "SPHK1 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_29370", "species_428203" ], "modifiers": [ [ "species_10769088", "catalyst" ] ], "additional_components": [ "YLR260W" ] }, "reaction_10785507": { "compartment": "compartment_876", "id": "reaction_10785507", "reactome": "R-SCE-8850854", "name": "NTPDase1 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8870906", "species_109276" ], "products": [ "species_8870962", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785501", "catalyst" ] ], "additional_components": [ "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10788350": { "compartment": "compartment_70101", "id": "reaction_10788350", "reactome": "R-SCE-9020258", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024768" ], "products": [ "species_9024759" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "CHEBI:81565", "CHEBI:81564", "species_158417", "Q10740", "YNL045W" ] }, "reaction_10784145": { "compartment": "compartment_70101", "id": "reaction_10784145", "reactome": "R-SCE-6801342", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803257", "species_113592" ], "products": [ "species_70106", "species_29370", "species_200640", "species_29372" ], "modifiers": [ [ "species_10784142", "catalyst" ] ], "additional_components": [ "YER183C" ] }, "reaction_10777793": { "compartment": "compartment_984", "id": "reaction_10777793", "reactome": "R-SCE-5433072", "name": "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490253", "species_109276" ], "products": [ "species_210382", "species_5490235" ], "modifiers": [ [ "species_10777790", "catalyst" ] ], "additional_components": [ "CHEBI:78587", "CHEBI:78581", "CHEBI:78579", "CHEBI:78584", "Q05902", "YLR299W" ] }, "reaction_10784767": { "compartment": "compartment_70101", "id": "reaction_10784767", "reactome": "R-SCE-6809764", "name": "SBF1 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784763", "species_10773465" ], "products": [ "species_10784765" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10773553": { "compartment": "compartment_876", "id": "reaction_10773553", "reactome": "R-SCE-1675994", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10773550", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "P47147", "YJR110W", "P50942", "YNL106C" ] }, "reaction_10771041": { "compartment": "compartment_5460", "id": "reaction_10771041", "reactome": "R-SCE-482812", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_482807", "species_113581" ], "products": [ "species_482803", "species_113593" ], "modifiers": [ [ "species_10771036", "catalyst" ] ], "additional_components": [ "species_29494", "species_500739", "species_29892", "species_110644", "species_30185", "species_30187", "species_29438", "species_110614", "species_29420", "CHEBI:60471", "CHEBI:58369", "CHEBI:58595", "CHEBI:57667", "species_110096", "species_110094", "CHEBI:58593", "P36010", "YKL067W" ] }, "reaction_10767033": { "compartment": "compartment_70101", "id": "reaction_10767033", "reactome": "R-SCE-197235", "name": "NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_197220" ], "products": [ "species_197256", "species_111294" ], "modifiers": [ [ "species_10767030", "catalyst" ] ], "additional_components": [ "Q06178", "YLR328W", "P53204", "YGR010W", "species_109496" ] }, "reaction_10765667": { "compartment": "compartment_7660", "id": "reaction_10765667", "reactome": "R-SCE-163664", "name": "AMP binds to gamma subunit of AMP kinase heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765661", "species_164121" ], "products": [ "species_10765665" ], "modifiers": [], "additional_components": [ "P34164", "YGL208W", "Q04739", "YER027C", "P32578", "YDR422C", "P12904", "YGL115W", "P38845", "YHR146W", "P06782", "YDR477W", "P53885", "YNL173C", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P32578", "YDR422C", "P12904", "YGL115W", "P38845", "YHR146W", "P06782", "YDR477W", "P53885", "YNL173C" ] }, "reaction_10787120": { "compartment": "compartment_70101", "id": "reaction_10787120", "reactome": "R-SCE-8932980", "name": "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_8932979" ], "modifiers": [ [ "species_10787109", "catalyst" ] ], "additional_components": [ "YDR105C" ] }, "reaction_10764159": { "compartment": "compartment_70101", "id": "reaction_10764159", "reactome": "R-SCE-75899", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76108" ], "products": [ "species_76103", "species_29372" ], "modifiers": [ [ "species_10764152", "catalyst" ] ], "additional_components": [ "YMR165C" ] }, "reaction_10769052": { "compartment": "compartment_17951", "id": "reaction_10769052", "reactome": "R-SCE-390250", "name": "3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193514", "species_390241" ], "products": [ "species_353123", "species_390246" ], "modifiers": [ [ "species_10769049", "catalyst" ] ], "additional_components": [ "YIL160C" ] }, "reaction_10773616": { "compartment": "compartment_20699", "id": "reaction_10773616", "reactome": "R-SCE-1676204", "name": "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806230", "species_29356" ], "products": [ "species_1806217", "species_29372" ], "modifiers": [ [ "species_10773611", "catalyst" ] ], "additional_components": [ "YNL128W" ] }, "reaction_10767527": { "compartment": "compartment_70101", "id": "reaction_10767527", "reactome": "R-SCE-200711", "name": "MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29460", "species_197969" ], "products": [ "species_29370", "species_111353", "species_29372" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10771991": { "compartment": "compartment_70101", "id": "reaction_10771991", "reactome": "R-SCE-964962", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965053", "species_113592" ], "products": [ "species_29370", "species_964952" ], "modifiers": [ [ "species_10771986", "catalyst" ] ], "additional_components": [ "species_158417", "P39988", "YEL029C" ] }, "reaction_10773140": { "compartment": "compartment_70616", "id": "reaction_10773140", "reactome": "R-SCE-1482850", "name": "MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498773", "species_1524083" ], "products": [ "species_1524072", "species_1524089" ], "modifiers": [ [ "species_10773113", "catalyst" ] ], "additional_components": [] }, "reaction_10773208": { "compartment": "compartment_12045", "id": "reaction_10773208", "reactome": "R-SCE-1482962", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500603", "species_1500596" ], "products": [ "species_109395", "species_1500581" ], "modifiers": [ [ "species_10773205", "catalyst" ] ], "additional_components": [ "P17898", "YNL130C", "P22140", "YHR123W", "species_113527", "species_109496" ] }, "reaction_10784770": { "compartment": "compartment_70101", "id": "reaction_10784770", "reactome": "R-SCE-6809777", "name": "PI3P is dephosphorylated to PI by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030", "species_29356" ], "products": [ "species_426639", "species_29372" ], "modifiers": [ [ "species_10784765", "catalyst" ] ], "additional_components": [ "P47147", "YJR110W" ] }, "reaction_10788208": { "compartment": "compartment_70101", "id": "reaction_10788208", "reactome": "R-SCE-9014627", "name": "SDS dimers:PXLP dehydrate L-Thr to 2AA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351990" ], "products": [ "species_9014643", "species_29356" ], "modifiers": [ [ "species_10788205", "catalyst" ] ], "additional_components": [ "P25379", "YCL064C" ] }, "reaction_10769066": { "compartment": "compartment_17951", "id": "reaction_10769066", "reactome": "R-SCE-390304", "name": "acetyl-CoA + H2O => acetate + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353123", "species_141343" ], "products": [ "species_193514", "species_390305" ], "modifiers": [ [ "species_10766854", "catalyst" ] ], "additional_components": [ "YJR019C" ] }, "reaction_10766152": { "compartment": "compartment_5460", "id": "reaction_10766152", "reactome": "R-SCE-169260", "name": "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766147", "species_31649" ], "products": [ "species_10766149", "species_113596" ], "modifiers": [ [ "species_10766147", "catalyst" ] ], "additional_components": [ "species_76577", "Q12480", "YPR004C", "P42940", "YGR207C", "species_113596", "species_76577", "species_31649", "Q12480", "YPR004C", "P42940", "YGR207C", "species_76577", "Q12480", "YPR004C", "P42940", "YGR207C", "species_113596" ] }, "reaction_10773039": { "compartment": "compartment_12045", "id": "reaction_10773039", "reactome": "R-SCE-1482636", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498724", "species_1500578" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10772920", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10772026": { "compartment": "compartment_70101", "id": "reaction_10772026", "reactome": "R-SCE-977333", "name": "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_977329" ], "products": [ "species_936706", "species_29406" ], "modifiers": [ [ "species_10772023", "catalyst" ] ], "additional_components": [ "P33330", "YOR184W" ] }, "reaction_10766425": { "compartment": "compartment_70101", "id": "reaction_10766425", "reactome": "R-SCE-177784", "name": "ribose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10761876", "catalyst" ] ], "additional_components": [ "YOR095C" ] }, "reaction_10762017": { "compartment": "compartment_70101", "id": "reaction_10762017", "reactome": "R-SCE-71590", "name": "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762014", "species_29372" ], "products": [ "species_10761967", "species_29548" ], "modifiers": [ [ "species_10762009", "catalyst" ] ], "additional_components": [ "P47011", "YJL137C", "species_113527", "P47011", "YJL137C", "species_113527", "P06738", "YPR160W" ] }, "reaction_10773054": { "compartment": "compartment_12045", "id": "reaction_10773054", "reactome": "R-SCE-1482691", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498722", "species_1500578" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10772920", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10774286": { "compartment": "compartment_70101", "id": "reaction_10774286", "reactome": "R-SCE-2393939", "name": "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1131972" ], "products": [ "species_73578", "species_76577" ], "modifiers": [ [ "species_10774283", "catalyst" ] ], "additional_components": [ "Q01976", "YBR111C", "species_109496" ] }, "reaction_10769044": { "compartment": "compartment_17951", "id": "reaction_10769044", "reactome": "R-SCE-389995", "name": "3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192307", "species_389982" ], "products": [ "species_389996", "species_193465", "species_192305" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10763073": { "compartment": "compartment_70101", "id": "reaction_10763073", "reactome": "R-SCE-73573", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29448", "species_111647" ], "products": [ "species_70106", "species_29372", "species_111628" ], "modifiers": [ [ "species_10763067", "catalyst" ] ], "additional_components": [ "P07259", "YJL130C", "P03965", "YJR109C" ] }, "reaction_10782024": { "compartment": "compartment_5460", "id": "reaction_10782024", "reactome": "R-SCE-6788798", "name": "AK4 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788802", "species_113593" ], "products": [ "species_113581", "species_6788801" ], "modifiers": [ [ "species_10782021", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "YER170W" ] }, "reaction_10773472": { "compartment": "compartment_172574", "id": "reaction_10773472", "reactome": "R-SCE-1675795", "name": "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806198", "species_29356" ], "products": [ "species_1806195", "species_29372" ], "modifiers": [ [ "species_10773463", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10769935": { "compartment": "compartment_70101", "id": "reaction_10769935", "reactome": "R-SCE-428701", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10769886", "catalyst" ] ], "additional_components": [ "P47013", "YJL134W", "P23501", "YKR053C" ] }, "reaction_10768244": { "compartment": "compartment_876", "id": "reaction_10768244", "reactome": "R-SCE-266046", "name": "GGT1, 5 dimers hydrolyse LTC4 to LTD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266013", "species_109276" ], "products": [ "species_210382", "species_266074" ], "modifiers": [ [ "species_10768241", "catalyst" ] ], "additional_components": [ "Q05902", "YLR299W" ] }, "reaction_10776221": { "compartment": "compartment_70101", "id": "reaction_10776221", "reactome": "R-SCE-3780994", "name": "GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10776213" ], "products": [ "species_10776218", "species_109402" ], "modifiers": [ [ "species_10776213", "catalyst" ] ], "additional_components": [ "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10771993": { "compartment": "compartment_70101", "id": "reaction_10771993", "reactome": "R-SCE-964970", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965131", "species_113592" ], "products": [ "species_29370", "species_29390" ], "modifiers": [ [ "species_10771986", "catalyst" ] ], "additional_components": [ "species_158417", "P39988", "YEL029C" ] }, "reaction_10773571": { "compartment": "compartment_20699", "id": "reaction_10773571", "reactome": "R-SCE-1676114", "name": "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806159", "species_29356" ], "products": [ "species_1524146", "species_29372" ], "modifiers": [ [ "species_10773568", "catalyst" ] ], "additional_components": [ "YKL212W" ] }, "reaction_10767728": { "compartment": "compartment_70101", "id": "reaction_10767728", "reactome": "R-SCE-203611", "name": "N-myristoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_184174", "species_10767726" ], "products": [ "species_10767644" ], "modifiers": [], "additional_components": [ "YHR042W", "YHR042W" ] }, "reaction_10773396": { "compartment": "compartment_70101", "id": "reaction_10773396", "reactome": "R-SCE-1614583", "name": "PXLP-K212-CTH cleaves L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614518", "species_29356" ], "products": [ "species_29382", "species_936714", "species_111707" ], "modifiers": [ [ "species_10773390", "catalyst" ] ], "additional_components": [ "P31373", "YAL012W" ] }, "reaction_10761549": { "compartment": "compartment_70101", "id": "reaction_10761549", "reactome": "R-SCE-70634", "name": "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498", "species_113567" ], "products": [ "species_113585", "species_29968" ], "modifiers": [ [ "species_10761546", "catalyst" ] ], "additional_components": [ "Q12375", "YOR130C", "P38087", "YBR104W", "P32331", "YPR058W" ] }, "reaction_10766880": { "compartment": "compartment_876", "id": "reaction_10766880", "reactome": "R-SCE-194153", "name": "ABCC3 transports bile salts from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_194156" ], "products": [ "species_29370", "species_192483", "species_29372" ], "modifiers": [ [ "species_10766877", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "CHEBI:16755", "species_193451", "CHEBI:16525", "CHEBI:28865", "CHEBI:36274", "CHEBI:17687", "CHEBI:16755", "species_193451", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274", "YGR281W" ] }, "reaction_10764658": { "compartment": "compartment_70101", "id": "reaction_10764658", "reactome": "R-SCE-110144", "name": "ADP + ADP <=> AMP + ATP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370" ], "products": [ "species_113592", "species_76577" ], "modifiers": [ [ "species_10764655", "catalyst" ] ], "additional_components": [ "YDR226W" ] }, "reaction_10785452": { "compartment": "compartment_12045", "id": "reaction_10785452", "reactome": "R-SCE-8848582", "name": "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848577", "species_200993" ], "products": [ "species_76194", "species_8848499" ], "modifiers": [ [ "species_10781638", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10766928": { "compartment": "compartment_70101", "id": "reaction_10766928", "reactome": "R-SCE-196350", "name": "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_29360" ], "products": [ "species_70106", "species_73473", "species_196344" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10761446": { "compartment": "compartment_5460", "id": "reaction_10761446", "reactome": "R-SCE-70555", "name": "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113561", "species_29896", "species_113593" ], "products": [ "species_29676", "species_113548", "species_113581" ], "modifiers": [ [ "species_10761443", "catalyst" ], [ "species_30471", "catalyst" ] ], "additional_components": [ "YJL130C" ] }, "reaction_10764500": { "compartment": "compartment_70101", "id": "reaction_10764500", "reactome": "R-SCE-109624", "name": "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500173", "species_113592" ], "products": [ "species_29370", "species_500088" ], "modifiers": [ [ "species_10764497", "catalyst" ] ], "additional_components": [ "species_83909", "CHEBI:17256", "species_76577", "species_109386", "P47143", "YJR105W", "species_109496" ] }, "reaction_10781620": { "compartment": "compartment_876", "id": "reaction_10781620", "reactome": "R-SCE-5696080", "name": "ALDH3B1 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_29356", "species_428663" ], "products": [ "species_70106", "species_73473", "species_3632881" ], "modifiers": [ [ "species_10781617", "catalyst" ] ], "additional_components": [ "YMR110C" ] }, "reaction_10773589": { "compartment": "compartment_876", "id": "reaction_10773589", "reactome": "R-SCE-1676145", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10773586", "catalyst" ] ], "additional_components": [ "P38994", "YDR208W" ] }, "reaction_10761466": { "compartment": "compartment_70101", "id": "reaction_10761466", "reactome": "R-SCE-70569", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29356" ], "products": [ "species_29498", "species_29514" ], "modifiers": [ [ "species_10761463", "catalyst" ] ], "additional_components": [ "P00812", "YPL111W", "species_113527" ] }, "reaction_10785455": { "compartment": "compartment_12045", "id": "reaction_10785455", "reactome": "R-SCE-8848585", "name": "AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30209", "species_200993" ], "products": [ "species_76194", "species_2534407" ], "modifiers": [ [ "species_10781638", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10766738": { "compartment": "compartment_70101", "id": "reaction_10766738", "reactome": "R-SCE-191380", "name": "Mevalonate is phosphorylated to mevalonate-5-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191424" ], "products": [ "species_29370", "species_191296" ], "modifiers": [ [ "species_10766735", "catalyst" ] ], "additional_components": [ "P07277", "YMR208W" ] }, "reaction_10772862": { "compartment": "compartment_5460", "id": "reaction_10772862", "reactome": "R-SCE-1362408", "name": "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772851", "species_10772838", "species_379721" ], "products": [ "species_10772853", "species_10772859", "species_379697" ], "modifiers": [ [ "species_10772838", "catalyst" ], [ "species_10772851", "catalyst" ] ], "additional_components": [ "CHEBI:33738", "Q12184", "YPL252C", "P25374", "YCL017C", "Q6Q560", "YER048W-A", "species_111793", "Q07540", "YFH1", "Q03020", "YPL135W", "P25374", "YCL017C", "Q6Q560", "YER048W-A", "CHEBI:33739", "Q07540", "YFH1", "Q03020", "YPL135W", "CHEBI:33737", "Q12184", "YPL252C", "P25374", "YCL017C", "Q6Q560", "YER048W-A", "species_111793", "Q07540", "YFH1", "Q03020", "YPL135W", "CHEBI:33738", "Q12184", "YPL252C" ] }, "reaction_10766930": { "compartment": "compartment_70101", "id": "reaction_10766930", "reactome": "R-SCE-196372", "name": "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193124", "species_29360" ], "products": [ "species_70106", "species_73473", "species_196366" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10774126": { "compartment": "compartment_17951", "id": "reaction_10774126", "reactome": "R-SCE-2066788", "name": "Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2066762", "species_193514" ], "products": [ "species_353123", "species_2066765" ], "modifiers": [ [ "species_10769049", "catalyst" ] ], "additional_components": [ "YIL160C" ] }, "reaction_10761825": { "compartment": "compartment_70101", "id": "reaction_10761825", "reactome": "R-SCE-71261", "name": "BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31369", "species_29368", "species_29406" ], "products": [ "species_113528", "species_30235", "species_29434" ], "modifiers": [ [ "species_10761822", "catalyst" ] ], "additional_components": [ "species_111793", "species_198816", "P23180", "YHL021C" ] }, "reaction_10761669": { "compartment": "compartment_5460", "id": "reaction_10761669", "reactome": "R-SCE-70975", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113587", "species_113559" ], "products": [ "species_29374", "species_29654" ], "modifiers": [ [ "species_10761666", "catalyst" ] ], "additional_components": [ "P00890", "CIT1" ] }, "reaction_10788352": { "compartment": "compartment_70101", "id": "reaction_10788352", "reactome": "R-SCE-9020270", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024577" ], "products": [ "species_9024570" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "CHEBI:138616", "CHEBI:138615", "species_158417", "Q10740", "YNL045W" ] }, "reaction_10764963": { "compartment": "compartment_70101", "id": "reaction_10764963", "reactome": "R-SCE-112034", "name": "PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500244", "species_83956" ], "products": [ "species_500245", "species_29372" ], "modifiers": [ [ "species_10763557", "catalyst" ] ], "additional_components": [ "species_112016", "CHEBI:58576", "CHEBI:17172", "CHEBI:16750", "Q05788", "YLR209C" ] }, "reaction_10778389": { "compartment": "compartment_17963", "id": "reaction_10778389", "reactome": "R-SCE-5653873", "name": "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70113" ], "products": [ "species_964746" ], "modifiers": [ [ "species_10778386", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10773283": { "compartment": "compartment_12045", "id": "reaction_10773283", "reactome": "R-SCE-1483121", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_426755" ], "products": [ "species_426955", "species_111294" ], "modifiers": [ [ "species_10773280", "catalyst" ] ], "additional_components": [ "P38221", "YBR029C", "species_109496" ] }, "reaction_10786171": { "compartment": "compartment_70101", "id": "reaction_10786171", "reactome": "R-SCE-8862380", "name": "HSD17B13 binds lipid droplets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866926", "species_10781197" ], "products": [ "species_10786169" ], "modifiers": [], "additional_components": [ "species_163579", "CHEBI:16247", "species_549167", "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C", "species_163579", "CHEBI:16247", "species_549167", "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C" ] }, "reaction_10766710": { "compartment": "compartment_70101", "id": "reaction_10766710", "reactome": "R-SCE-191323", "name": "HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191293", "species_29356", "species_76183" ], "products": [ "species_70106", "species_76194", "species_191374" ], "modifiers": [ [ "species_10766707", "catalyst" ] ], "additional_components": [ "YML126C" ] }, "reaction_10761158": { "compartment": "compartment_70101", "id": "reaction_10761158", "reactome": "R-SCE-70369", "name": "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29452" ], "products": [ "species_29410" ], "modifiers": [ [ "species_10761155", "catalyst" ] ], "additional_components": [ "P04397", "YBR019C", "species_113526" ] }, "reaction_10773537": { "compartment": "compartment_20699", "id": "reaction_10773537", "reactome": "R-SCE-1675961", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806159" ], "modifiers": [ [ "species_10773532", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "species_113527" ] }, "reaction_10781258": { "compartment": "compartment_12045", "id": "reaction_10781258", "reactome": "R-SCE-5693761", "name": "FA2H hydroxylates CERA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_428256" ], "products": [ "species_5693768", "species_29356" ], "modifiers": [ [ "species_10781255", "catalyst" ] ], "additional_components": [ "YMR272C" ] }, "reaction_10786994": { "compartment": "compartment_984", "id": "reaction_10786994", "reactome": "R-SCE-8878787", "name": "ALPI dimer hydrolyses phosphate monoesters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8878780", "species_109276" ], "products": [ "species_109277", "species_8878776" ], "modifiers": [ [ "species_10786991", "catalyst" ] ], "additional_components": [ "species_158417", "P11491", "YDR481C", "species_74016" ] }, "reaction_10785449": { "compartment": "compartment_12045", "id": "reaction_10785449", "reactome": "R-SCE-8848580", "name": "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_76194", "species_1500594" ], "modifiers": [ [ "species_10785444", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10784665": { "compartment": "compartment_5460", "id": "reaction_10784665", "reactome": "R-SCE-6808487", "name": "ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6808499", "species_113563", "species_113521" ], "products": [ "species_113600", "species_200679", "species_29376", "species_113529" ], "modifiers": [ [ "species_10784662", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10764630": { "compartment": "compartment_70101", "id": "reaction_10764630", "reactome": "R-SCE-109903", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500759", "species_113592" ], "products": [ "species_29370", "species_500761" ], "modifiers": [ [ "species_10764627", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:16704", "species_109395", "species_109402", "Q12084", "YDR020C" ] }, "reaction_10773579": { "compartment": "compartment_20699", "id": "reaction_10773579", "reactome": "R-SCE-1676133", "name": "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806217" ], "products": [ "species_1524146", "species_29372" ], "modifiers": [ [ "species_10773568", "catalyst" ] ], "additional_components": [ "YKL212W" ] }, "reaction_10761634": { "compartment": "compartment_5460", "id": "reaction_10761634", "reactome": "R-SCE-70938", "name": "lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113600", "species_29444", "species_113529" ], "products": [ "species_113563", "species_113521", "species_30176" ], "modifiers": [ [ "species_10761631", "catalyst" ] ], "additional_components": [ "P38999", "YNR050C" ] }, "reaction_10761228": { "compartment": "compartment_70101", "id": "reaction_10761228", "reactome": "R-SCE-70420", "name": "HK1,2,3,GCK phosphorylate Glc to form G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_70113" ], "products": [ "species_70106", "species_29370", "species_30537" ], "modifiers": [ [ "species_10761225", "catalyst" ] ], "additional_components": [ "Q04409", "YDR516C", "Q06204", "YLR446W", "P04806", "YFR053C", "P17709", "YCL040W", "P04807", "YGL253W" ] }, "reaction_10788344": { "compartment": "compartment_70101", "id": "reaction_10788344", "reactome": "R-SCE-9020252", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024602", "species_29356" ], "products": [ "species_9024574" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "CHEBI:138179", "CHEBI:138614", "species_158417", "Q10740", "YNL045W" ] }, "reaction_10766553": { "compartment": "compartment_70101", "id": "reaction_10766553", "reactome": "R-SCE-189425", "name": "UROD decarboxylates URO3 to COPRO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189407" ], "products": [ "species_113528", "species_189455" ], "modifiers": [ [ "species_10766550", "catalyst" ] ], "additional_components": [ "P32347", "YDR047W" ] }, "reaction_10766603": { "compartment": "compartment_70101", "id": "reaction_10766603", "reactome": "R-SCE-190141", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766560", "species_190173" ], "products": [ "species_29426", "species_10766601" ], "modifiers": [], "additional_components": [ "species_158417", "P05373", "YGL040C", "species_158417", "species_190173", "P05373", "YGL040C" ] }, "reaction_10761871": { "compartment": "compartment_70101", "id": "reaction_10761871", "reactome": "R-SCE-71303", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29732" ], "products": [ "species_29790" ], "modifiers": [ [ "species_10761868", "catalyst" ] ], "additional_components": [ "P46969", "YJL121C", "species_111793" ] }, "reaction_10766563": { "compartment": "compartment_70101", "id": "reaction_10766563", "reactome": "R-SCE-189439", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189489" ], "products": [ "species_70106", "species_189464", "species_29356" ], "modifiers": [ [ "species_10766560", "catalyst" ] ], "additional_components": [ "species_158417", "P05373", "YGL040C" ] }, "reaction_10766915": { "compartment": "compartment_70101", "id": "reaction_10766915", "reactome": "R-SCE-194718", "name": "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_194657" ], "products": [ "species_73473", "species_70106", "species_194661", "species_113528" ], "modifiers": [ [ "species_10766887", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10774123": { "compartment": "compartment_17951", "id": "reaction_10774123", "reactome": "R-SCE-2066780", "name": "Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2066766" ], "products": [ "species_2066762" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10784308": { "compartment": "compartment_70101", "id": "reaction_10784308", "reactome": "R-SCE-6806877", "name": "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8866401" ], "products": [ "species_29370", "species_6806881" ], "modifiers": [ [ "species_10784305", "catalyst" ] ], "additional_components": [ "P36010", "YKL067W" ] }, "reaction_10784740": { "compartment": "compartment_70101", "id": "reaction_10784740", "reactome": "R-SCE-6809309", "name": "MTMR6 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773548", "species_10784724" ], "products": [ "species_10784738" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10763122": { "compartment": "compartment_70101", "id": "reaction_10763122", "reactome": "R-SCE-73596", "name": "dCMP + H2O => dUMP + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_109378", "species_29356" ], "products": [ "species_109382", "species_31633" ], "modifiers": [ [ "species_10763119", "catalyst" ] ], "additional_components": [ "P06773", "YHR144C" ] }, "reaction_10769900": { "compartment": "compartment_70101", "id": "reaction_10769900", "reactome": "R-SCE-428681", "name": "sphinganine 1-phosphate => phosphoethanolamine + hexadecanal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428275" ], "products": [ "species_428686", "species_428663" ], "modifiers": [ [ "species_10769895", "catalyst" ] ], "additional_components": [ "YDR294C" ] }, "reaction_10770866": { "compartment": "compartment_5460", "id": "reaction_10770866", "reactome": "R-SCE-450975", "name": "isocitrate <=> citrate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29938" ], "products": [ "species_29654" ], "modifiers": [ [ "species_10761657", "catalyst" ] ], "additional_components": [] }, "reaction_10766533": { "compartment": "compartment_17927", "id": "reaction_10766533", "reactome": "R-SCE-189421", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189411", "species_189461" ], "products": [ "species_189481", "species_189480", "species_189478" ], "modifiers": [ [ "species_10766530", "catalyst" ] ], "additional_components": [ "P11353", "YDR044W" ] }, "reaction_10763393": { "compartment": "compartment_70101", "id": "reaction_10763393", "reactome": "R-SCE-73814", "name": "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_113592", "species_111292" ], "products": [ "species_70106", "species_29370", "species_111338", "species_29372" ], "modifiers": [ [ "species_10763376", "catalyst" ] ], "additional_components": [ "YGL234W" ] }, "reaction_10771060": { "compartment": "compartment_70101", "id": "reaction_10771060", "reactome": "R-SCE-504054", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29494", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_110614", "species_29372" ], "modifiers": [ [ "species_10771057", "catalyst" ] ], "additional_components": [ "P28274", "YBL039C", "P38627", "YJR103W" ] }, "reaction_10784318": { "compartment": "compartment_5460", "id": "reaction_10784318", "reactome": "R-SCE-6806966", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807473" ], "products": [ "species_6807477" ], "modifiers": [ [ "species_10784315", "catalyst" ] ], "additional_components": [ "P40165", "YNL200C" ] }, "reaction_10778609": { "compartment": "compartment_70101", "id": "reaction_10778609", "reactome": "R-SCE-5662471", "name": "SORD tetramer oxidizes xylitol to D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5660033", "species_29360" ], "products": [ "species_70106", "species_73473", "species_5661281" ], "modifiers": [ [ "species_10778317", "catalyst" ] ], "additional_components": [ "Q07993", "YLR070C", "species_158417", "Q07786", "YDL246C", "P35497", "YJR159W" ] }, "reaction_10773555": { "compartment": "compartment_172574", "id": "reaction_10773555", "reactome": "R-SCE-1676024", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806195" ], "products": [ "species_29370", "species_1806198" ], "modifiers": [ [ "species_10773532", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "species_113527" ] }, "reaction_10773582": { "compartment": "compartment_876", "id": "reaction_10773582", "reactome": "R-SCE-1676134", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_1806224" ], "modifiers": [ [ "species_10773418", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10775627": { "compartment": "compartment_70101", "id": "reaction_10775627", "reactome": "R-SCE-3323111", "name": "Cytoslic carboxylases translocate to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774825" ], "products": [ "species_10774951" ], "modifiers": [], "additional_components": [ "P11154", "YGL062W", "species_113527", "P11154", "YGL062W", "species_113527" ] }, "reaction_10772944": { "compartment": "compartment_12045", "id": "reaction_10772944", "reactome": "R-SCE-1482543", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_29356" ], "products": [ "species_76116", "species_1500593" ], "modifiers": [ [ "species_10772941", "catalyst" ] ], "additional_components": [ "P28321", "YKL094W" ] }, "reaction_10766885": { "compartment": "compartment_70101", "id": "reaction_10766885", "reactome": "R-SCE-194641", "name": "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194644", "species_29368" ], "products": [ "species_29366", "species_194735", "species_29356" ], "modifiers": [ [ "species_10766882", "catalyst" ] ], "additional_components": [ "YGR060W" ] }, "reaction_10766847": { "compartment": "compartment_70101", "id": "reaction_10766847", "reactome": "R-SCE-193052", "name": "Pregn-5-ene-3,20-dione isomerizes to progesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196344" ], "products": [ "species_193055" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10761580": { "compartment": "compartment_5460", "id": "reaction_10761580", "reactome": "R-SCE-70670", "name": "PRODH oxidises L-Pro to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_379717", "species_113597" ], "products": [ "species_164934", "species_113529", "species_113590" ], "modifiers": [ [ "species_10761577", "catalyst" ] ], "additional_components": [ "YLR142W" ] }, "reaction_10768933": { "compartment": "compartment_17951", "id": "reaction_10768933", "reactome": "R-SCE-389611", "name": "2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389594" ], "products": [ "species_389578", "species_389636" ], "modifiers": [ [ "species_10768930", "catalyst" ] ], "additional_components": [ "species_29480", "species_109496", "P39994", "YEL020C" ] }, "reaction_10772867": { "compartment": "compartment_5460", "id": "reaction_10772867", "reactome": "R-SCE-1362416", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772865", "species_113531" ], "products": [ "species_10772838" ], "modifiers": [], "additional_components": [ "P25374", "YCL017C", "Q6Q560", "YER048W-A", "Q07540", "YFH1", "Q03020", "YPL135W", "P25374", "YCL017C", "Q6Q560", "YER048W-A", "species_111793", "Q07540", "YFH1", "Q03020", "YPL135W" ] }, "reaction_10767499": { "compartment": "compartment_70101", "id": "reaction_10767499", "reactome": "R-SCE-200661", "name": "MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111353" ], "products": [ "species_200640", "species_29356" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10774100": { "compartment": "compartment_12045", "id": "reaction_10774100", "reactome": "R-SCE-2046093", "name": "Translocation of tetracosapentaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046050", "species_211579" ], "products": [ "species_2046055", "species_5228339", "species_211606" ], "modifiers": [ [ "species_10768821", "catalyst" ] ], "additional_components": [ "YPL147W" ] }, "reaction_10787692": { "compartment": "compartment_70101", "id": "reaction_10787692", "reactome": "R-SCE-8955760", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800", "species_30537" ], "products": [ "species_70106", "species_29728", "species_8955759" ], "modifiers": [ [ "species_10761123", "catalyst" ] ], "additional_components": [ "Q03262", "YMR278W", "species_109496" ] }, "reaction_10784147": { "compartment": "compartment_5460", "id": "reaction_10784147", "reactome": "R-SCE-6801456", "name": "MTHFD1L transforms 10-formyl-THF to HCOOH and THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5389850", "species_113548", "species_113581" ], "products": [ "species_200671", "species_6801451", "species_113593" ], "modifiers": [ [ "species_10781645", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10770911": { "compartment": "compartment_5460", "id": "reaction_10770911", "reactome": "R-SCE-452036", "name": "arginine + H2O => ornithine + urea [ARG2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_374064" ], "products": [ "species_113585", "species_374061" ], "modifiers": [ [ "species_10770908", "catalyst" ] ], "additional_components": [ "P00812", "YPL111W", "species_113527" ] }, "reaction_10766849": { "compartment": "compartment_70101", "id": "reaction_10766849", "reactome": "R-SCE-193073", "name": "HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_176626" ], "products": [ "species_70106", "species_73473", "species_193079" ], "modifiers": [ [ "species_10766844", "catalyst" ] ], "additional_components": [ "P53199", "YGL001C" ] }, "reaction_10769061": { "compartment": "compartment_17951", "id": "reaction_10769061", "reactome": "R-SCE-390284", "name": "propionyl-CoA + carnitine => propionylcarnitine + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390294", "species_192314" ], "products": [ "species_193514", "species_390274" ], "modifiers": [ [ "species_10769058", "catalyst" ] ], "additional_components": [ "YML042W" ] }, "reaction_10763317": { "compartment": "compartment_70101", "id": "reaction_10763317", "reactome": "R-SCE-73792", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111584", "species_29472", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29404", "species_111294", "species_76577", "species_113578" ], "modifiers": [ [ "species_10763314", "catalyst" ] ], "additional_components": [ "YMR217W" ] }, "reaction_10781076": { "compartment": "compartment_70101", "id": "reaction_10781076", "reactome": "R-SCE-5692237", "name": "ADH5 oxidises S-HMGSH to S-FGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5692221", "species_29360" ], "products": [ "species_73473", "species_70106", "species_5692249" ], "modifiers": [ [ "species_10781073", "catalyst" ] ], "additional_components": [ "species_158417", "P32771", "YDL168W" ] }, "reaction_10767529": { "compartment": "compartment_70101", "id": "reaction_10767529", "reactome": "R-SCE-200718", "name": "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200640" ], "products": [ "species_29366", "species_200739" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10774098": { "compartment": "compartment_17957", "id": "reaction_10774098", "reactome": "R-SCE-2046087", "name": "Translocation of tetracosahexaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046054", "species_211579" ], "products": [ "species_2046047", "species_211606", "species_426639" ], "modifiers": [ [ "species_10768821", "catalyst" ] ], "additional_components": [ "YPL147W" ] }, "reaction_10767537": { "compartment": "compartment_70101", "id": "reaction_10767537", "reactome": "R-SCE-200740", "name": "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200640", "species_29356" ], "products": [ "species_111353" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10769032": { "compartment": "compartment_17951", "id": "reaction_10769032", "reactome": "R-SCE-389889", "name": "ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389893", "species_113535" ], "products": [ "species_389894", "species_113575" ], "modifiers": [ [ "species_10769029", "catalyst" ] ], "additional_components": [ "P13711", "YGL205W", "species_113596" ] }, "reaction_10766890": { "compartment": "compartment_70101", "id": "reaction_10766890", "reactome": "R-SCE-194642", "name": "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194735", "species_29360" ], "products": [ "species_70106", "species_73473", "species_113528", "species_194667" ], "modifiers": [ [ "species_10766887", "catalyst" ] ], "additional_components": [ "YGL001C" ] }, "reaction_10764323": { "compartment": "compartment_70101", "id": "reaction_10764323", "reactome": "R-SCE-76590", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76577", "species_29356" ], "products": [ "species_29602", "species_31633" ], "modifiers": [ [ "species_10764320", "catalyst" ] ], "additional_components": [ "P38150", "YJL070C", "P15274", "YML035C", "P40361", "YJL070C" ] }, "reaction_10761802": { "compartment": "compartment_70101", "id": "reaction_10761802", "reactome": "R-SCE-71218", "name": "3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_30487" ], "products": [ "species_36027" ], "modifiers": [ [ "species_10761799", "catalyst" ] ], "additional_components": [ "P47096", "YJR025C", "species_111793" ] }, "reaction_10765675": { "compartment": "compartment_7660", "id": "reaction_10765675", "reactome": "R-SCE-163748", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10764091" ], "modifiers": [], "additional_components": [ "YDL052C" ] }, "reaction_10779627": { "compartment": "compartment_12045", "id": "reaction_10779627", "reactome": "R-SCE-5689000", "name": "AADAC deacetylates PHEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5689006", "species_29356" ], "products": [ "species_5688995", "species_5689001" ], "modifiers": [ [ "species_10779624", "catalyst" ] ], "additional_components": [ "YGR263C" ] }, "reaction_10781992": { "compartment": "compartment_70101", "id": "reaction_10781992", "reactome": "R-SCE-6787329", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_112016" ], "products": [ "species_73578" ], "modifiers": [ [ "species_10761119", "catalyst" ] ], "additional_components": [ "Q03262", "YMR278W", "species_109496" ] }, "reaction_10763550": { "compartment": "compartment_70101", "id": "reaction_10763550", "reactome": "R-SCE-74213", "name": "APRT catalyzes the conversion of adenine to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_83951" ], "products": [ "species_111294", "species_76577" ], "modifiers": [ [ "species_10763547", "catalyst" ] ], "additional_components": [ "P49435", "YML022W" ] }, "reaction_10766581": { "compartment": "compartment_5460", "id": "reaction_10766581", "reactome": "R-SCE-189442", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70958", "species_159549", "species_113529" ], "products": [ "species_29374", "species_189466", "species_29376" ], "modifiers": [ [ "species_10766578", "catalyst" ], [ "species_189444", "inhibitor" ] ], "additional_components": [ "P09950", "YDR232W" ] }, "reaction_10787970": { "compartment": "compartment_70101", "id": "reaction_10787970", "reactome": "R-SCE-9012374", "name": "VDAC1 transports PYR from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398" ], "products": [ "species_9012375" ], "modifiers": [ [ "species_10777036", "catalyst" ] ], "additional_components": [ "P04840", "POR1", "P40478", "YIL114C" ] }, "reaction_10780397": { "compartment": "compartment_17951", "id": "reaction_10780397", "reactome": "R-SCE-5690042", "name": "Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_5690520" ], "products": [ "species_193514", "species_5690539" ], "modifiers": [ [ "species_10766854", "catalyst" ] ], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "species_382577", "CHEBI:59554", "YJR019C" ] }, "reaction_10761921": { "compartment": "compartment_5460", "id": "reaction_10761921", "reactome": "R-SCE-71401", "name": "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113594", "species_113526" ], "products": [ "species_29376", "species_70958", "species_29362" ], "modifiers": [ [ "species_10761760", "catalyst" ] ], "additional_components": [ "species_29480", "P20967", "YIL125W", "CHEBI:17460", "P09624", "YFL018C", "species_113596", "P19262", "YDR148C" ] }, "reaction_10773344": { "compartment": "compartment_70101", "id": "reaction_10773344", "reactome": "R-SCE-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1498751" ], "products": [ "species_29370", "species_428686" ], "modifiers": [ [ "species_10773341", "catalyst" ] ], "additional_components": [ "P20485", "YLR133W", "Q03764", "YDR147W" ] }, "reaction_10769039": { "compartment": "compartment_17951", "id": "reaction_10769039", "reactome": "R-SCE-389891", "name": "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389893", "species_113535" ], "products": [ "species_389894", "species_113575" ], "modifiers": [ [ "species_10769036", "catalyst" ] ], "additional_components": [ "P13711", "YGL205W", "species_113596" ] }, "reaction_10769019": { "compartment": "compartment_17951", "id": "reaction_10769019", "reactome": "R-SCE-389842", "name": "HAO1 tetramer oxidizes glycolate to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389822", "species_113535" ], "products": [ "species_389678", "species_113575" ], "modifiers": [ [ "species_10769016", "catalyst" ] ], "additional_components": [ "species_73524", "P00175", "CYB2" ] }, "reaction_10785562": { "compartment": "compartment_984", "id": "reaction_10785562", "reactome": "R-SCE-8851356", "name": "NTPDase5 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936165", "species_109276" ], "products": [ "species_109277", "species_351626", "species_8851369" ], "modifiers": [ [ "species_10785559", "catalyst" ] ], "additional_components": [ "species_29420", "species_29370", "species_110094", "species_110096", "species_109395", "species_76577", "species_109402", "species_113578", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10773047": { "compartment": "compartment_12045", "id": "reaction_10773047", "reactome": "R-SCE-1482667", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498738", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10773037", "catalyst" ] ], "additional_components": [ "YOR175C" ] }, "reaction_10774299": { "compartment": "compartment_5460", "id": "reaction_10774299", "reactome": "R-SCE-2395517", "name": "NADPH transfers electrons to FDXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_10774295", "species_113529" ], "products": [ "species_10774293", "species_113563" ], "modifiers": [], "additional_components": [ "P48360", "YDR376W", "species_113596", "P48360", "YDR376W", "species_31649" ] }, "reaction_10761456": { "compartment": "compartment_5460", "id": "reaction_10761456", "reactome": "R-SCE-70560", "name": "carbamoyl phosphate + ornithine => citrulline + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29676", "species_113585" ], "products": [ "species_113548", "species_113567" ], "modifiers": [ [ "species_10761453", "catalyst" ] ], "additional_components": [ "P05150", "YJL088W" ] }, "reaction_10763572": { "compartment": "compartment_70101", "id": "reaction_10763572", "reactome": "R-SCE-74255", "name": "Guanine + H2O => Xanthine + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29356", "species_83956" ], "products": [ "species_30064", "species_31633" ], "modifiers": [ [ "species_10763569", "catalyst" ] ], "additional_components": [ "species_158417", "Q07729", "YDL238C" ] }, "reaction_10773257": { "compartment": "compartment_70616", "id": "reaction_10773257", "reactome": "R-SCE-1483063", "name": "PG and CDP-DAG are converted to CL by CRLS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_1524064" ], "products": [ "species_1524067", "species_1524072" ], "modifiers": [ [ "species_10772962", "catalyst" ] ], "additional_components": [ "YDL142C" ] }, "reaction_10785439": { "compartment": "compartment_17957", "id": "reaction_10785439", "reactome": "R-SCE-8848246", "name": "DBI, ACBD7 bind MCFA-CoA and LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848288", "species_10785433" ], "products": [ "species_10785437" ], "modifiers": [], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "YGR037C", "CHEBI:33184", "CHEBI:61907", "P31787", "YGR037C" ] }, "reaction_10765739": { "compartment": "compartment_70616", "id": "reaction_10765739", "reactome": "R-SCE-164651", "name": "Electron transfer from ubiquinol to cytochrome c of complex III", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76633", "species_10765569", "species_113529", "species_73663" ], "products": [ "species_76633", "species_10765567", "species_163953", "species_73663" ], "modifiers": [ [ "species_10765736", "catalyst" ] ], "additional_components": [ "P00045", "YEL039C", "P00044", "YJR048W", "CHEBI:38574", "P00045", "YEL039C", "P00044", "YJR048W", "CHEBI:38573", "P11914", "MAS2", "P00128", "YDR529C", "P10507", "MAS1", "P07256", "YBL045C", "P08067", "YEL024W", "P00163", "Q0105", "P07143", "CYT1", "P22289", "YGR183C", "P00127", "YFR033C", "P08525", "YJL166W" ] }, "reaction_10766892": { "compartment": "compartment_70101", "id": "reaction_10766892", "reactome": "R-SCE-194669", "name": "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194723", "species_29368" ], "products": [ "species_29366", "species_29356", "species_194657" ], "modifiers": [ [ "species_10766882", "catalyst" ] ], "additional_components": [ "YGR060W" ] }, "reaction_10789271": { "compartment": "compartment_70101", "id": "reaction_10789271", "reactome": "R-SCE-9717834", "name": "GGPS1 hexamer transfers IPPP to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191324" ], "products": [ "species_191409", "species_111294" ], "modifiers": [ [ "species_10789265", "catalyst" ] ], "additional_components": [ "Q12051", "YPL069C", "species_109496" ] }, "reaction_10775602": { "compartment": "compartment_70101", "id": "reaction_10775602", "reactome": "R-SCE-3322019", "name": "Autoglucosylation of GYG2 complexed with GYS2-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775597" ], "products": [ "species_110096", "species_10775599" ], "modifiers": [ [ "species_10775597", "catalyst" ] ], "additional_components": [ "P27472", "YLR258W", "P47011", "YJL137C", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P27472", "YLR258W", "P47011", "YJL137C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10775616": { "compartment": "compartment_70101", "id": "reaction_10775616", "reactome": "R-SCE-3322057", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775609" ], "products": [ "species_10775614" ], "modifiers": [ [ "species_10775557", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "YEL011W" ] }, "reaction_10785555": { "compartment": "compartment_17963", "id": "reaction_10785555", "reactome": "R-SCE-8851234", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851233", "species_2022884" ], "products": [ "species_425969", "species_8851224", "species_8851226" ], "modifiers": [ [ "species_10785549", "catalyst" ] ], "additional_components": [ "species_29494", "species_30187", "species_29438", "species_110614", "species_29420", "CHEBI:58369", "species_110094", "species_110096", "P40009", "YER005W", "species_74016" ] }, "reaction_10766160": { "compartment": "compartment_5460", "id": "reaction_10766160", "reactome": "R-SCE-169270", "name": "ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766149", "species_73663" ], "products": [ "species_76633", "species_10766147" ], "modifiers": [ [ "species_10766157", "catalyst" ] ], "additional_components": [ "species_76577", "species_31649", "Q12480", "YPR004C", "P42940", "YGR207C", "species_76577", "Q12480", "YPR004C", "P42940", "YGR207C", "species_113596", "YOR356W" ] }, "reaction_10769932": { "compartment": "compartment_70101", "id": "reaction_10769932", "reactome": "R-SCE-428696", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10769929", "catalyst" ] ], "additional_components": [ "Q05521", "YDR284C", "Q04396", "YDR503C" ] }, "reaction_10781083": { "compartment": "compartment_12045", "id": "reaction_10781083", "reactome": "R-SCE-5692261", "name": "ALDH3A2-1 oxidises HD2NAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_29356", "species_428671" ], "products": [ "species_70106", "species_73473", "species_3632881" ], "modifiers": [ [ "species_10781080", "catalyst" ] ], "additional_components": [ "Q04458", "YMR110C" ] }, "reaction_10770608": { "compartment": "compartment_5460", "id": "reaction_10770608", "reactome": "R-SCE-449911", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113539", "species_113593" ], "products": [ "species_159448", "species_159450", "species_113559" ], "modifiers": [ [ "species_10770605", "catalyst" ] ], "additional_components": [ "YAL054C" ] }, "reaction_10775516": { "compartment": "compartment_70101", "id": "reaction_10775516", "reactome": "R-SCE-3322001", "name": "GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775511" ], "products": [ "species_110096", "species_10775513" ], "modifiers": [ [ "species_10775511", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10773288": { "compartment": "compartment_70616", "id": "reaction_10773288", "reactome": "R-SCE-1483165", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110577", "species_1524101" ], "products": [ "species_1524064", "species_159450" ], "modifiers": [ [ "species_10773285", "catalyst" ] ], "additional_components": [ "YBR029C" ] }, "reaction_10763560": { "compartment": "compartment_70101", "id": "reaction_10763560", "reactome": "R-SCE-74242", "name": "PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500172", "species_29372" ], "products": [ "species_113599", "species_500244" ], "modifiers": [ [ "species_10763557", "catalyst" ] ], "additional_components": [ "CHEBI:28997", "CHEBI:17596", "species_112016", "CHEBI:58576", "Q05788", "YLR209C" ] }, "reaction_10789066": { "compartment": "compartment_70101", "id": "reaction_10789066", "reactome": "R-SCE-9678749", "name": "IMPDH tetramers binds IMPDH inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763342", "species_9678719" ], "products": [ "species_10763345" ], "modifiers": [], "additional_components": [ "P38697", "YHR216W", "P50095", "YLR432W", "P50094", "YML056C", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842", "P38697", "YHR216W", "P50095", "YLR432W", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842", "P50094", "YML056C" ] }, "reaction_10773306": { "compartment": "compartment_12045", "id": "reaction_10773306", "reactome": "R-SCE-1483182", "name": "PC is hydrolyzed to PA and choline by PLD1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_264618", "species_426755" ], "modifiers": [ [ "species_10773301", "catalyst" ] ], "additional_components": [ "YKR031C" ] }, "reaction_10763387": { "compartment": "compartment_70101", "id": "reaction_10763387", "reactome": "R-SCE-73812", "name": "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111354", "species_29472", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29370", "species_111369", "species_29404", "species_29372" ], "modifiers": [ [ "species_10763384", "catalyst" ] ], "additional_components": [ "YGR061C" ] }, "reaction_10763132": { "compartment": "compartment_70101", "id": "reaction_10763132", "reactome": "R-SCE-73599", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500759", "species_113592" ], "products": [ "species_29370", "species_500761" ], "modifiers": [ [ "species_10763129", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:16704", "species_109395", "species_109402", "Q12084", "YDR020C" ] }, "reaction_10775579": { "compartment": "compartment_70101", "id": "reaction_10775579", "reactome": "R-SCE-3322009", "name": "GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_10775574" ], "products": [ "species_110096", "species_10775576" ], "modifiers": [ [ "species_10775574", "catalyst" ] ], "additional_components": [ "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C" ] }, "reaction_10789268": { "compartment": "compartment_70101", "id": "reaction_10789268", "reactome": "R-SCE-9717830", "name": "GGPS1 hexamer transfers IPPP to GPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191409" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10789265", "catalyst" ] ], "additional_components": [ "Q12051", "YPL069C", "species_109496" ] }, "reaction_10779036": { "compartment": "compartment_12045", "id": "reaction_10779036", "reactome": "R-SCE-5676637", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676631" ], "products": [ "species_5676634", "species_29356" ], "modifiers": [ [ "species_10779031", "catalyst" ] ], "additional_components": [ "YJL097W" ] }, "reaction_10788222": { "compartment": "compartment_70101", "id": "reaction_10788222", "reactome": "R-SCE-9014766", "name": "PXLP-K56-SRR dimer isomerises L-Ser to D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_376186" ], "modifiers": [ [ "species_10788216", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "P36007", "YKL218C" ] }, "reaction_10764143": { "compartment": "compartment_70101", "id": "reaction_10764143", "reactome": "R-SCE-75889", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_75970" ], "products": [ "species_29360", "species_76114" ], "modifiers": [ [ "species_10764140", "catalyst" ] ], "additional_components": [ "P41911", "YOL059W", "Q00055", "YDL022W" ] }, "reaction_10763361": { "compartment": "compartment_70101", "id": "reaction_10763361", "reactome": "R-SCE-73798", "name": "AICAR + 10-Formyl-THF => FAICAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111409", "species_419151" ], "products": [ "species_111427", "species_111355" ], "modifiers": [ [ "species_10763355", "catalyst" ] ], "additional_components": [ "P38009", "YMR120C" ] }, "reaction_10763112": { "compartment": "compartment_70101", "id": "reaction_10763112", "reactome": "R-SCE-73580", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_73578" ], "products": [ "species_73566", "species_76577" ], "modifiers": [ [ "species_10763109", "catalyst" ] ], "additional_components": [ "P38063", "YBL068W", "P32895", "YKL181W", "P38689", "YHL011C", "Q12265", "YOL061W", "P38620", "YER099C" ] }, "reaction_10762072": { "compartment": "compartment_70101", "id": "reaction_10762072", "reactome": "R-SCE-71670", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29370", "species_29492" ], "products": [ "species_113592", "species_29398" ], "modifiers": [ [ "species_10762069", "catalyst" ], [ "species_30014", "catalyst" ], [ "species_76183", "inhibitor" ], [ "species_30389", "inhibitor" ], [ "species_29358", "inhibitor" ] ], "additional_components": [ "P00549", "YAL038W", "species_74126", "species_109496", "P52489", "YOR347C" ] }, "reaction_10775607": { "compartment": "compartment_70101", "id": "reaction_10775607", "reactome": "R-SCE-3322025", "name": "Autoglucosylation of GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775604", "species_29410" ], "products": [ "species_110096", "species_10775511" ], "modifiers": [ [ "species_10775604", "catalyst" ] ], "additional_components": [ "P46958", "YJL146W", "P27472", "YLR258W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P47011", "YJL137C", "P27472", "YLR258W", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W", "P46958", "YJL146W", "P27472", "YLR258W", "P47011", "YJL137C", "Q12096", "YOR320C", "species_109496", "P36143", "YKR058W" ] }, "reaction_10785160": { "compartment": "compartment_70101", "id": "reaction_10785160", "reactome": "R-SCE-6813749", "name": "ALDH1A1 oxidises GA to DGA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30393", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_6799497" ], "modifiers": [ [ "species_10762101", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10773606": { "compartment": "compartment_20699", "id": "reaction_10773606", "reactome": "R-SCE-1676185", "name": "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10773603", "catalyst" ] ], "additional_components": [ "P37297", "YLR305C", "P42951", "YJL100W" ] }, "reaction_10776478": { "compartment": "compartment_70101", "id": "reaction_10776478", "reactome": "R-SCE-4167511", "name": "HLCS biotinylates ACACB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_113592", "species_10776476" ], "products": [ "species_10767433", "species_111294", "species_76577" ], "modifiers": [ [ "species_10774830", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527", "Q00955", "YNR016C", "species_113527", "YDL141W" ] }, "reaction_10767652": { "compartment": "compartment_20699", "id": "reaction_10767652", "reactome": "R-SCE-202132", "name": "depalmitoylated eNOS translocates from plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767646" ], "products": [ "species_10767650" ], "modifiers": [], "additional_components": [ "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_29870", "species_113596", "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_29870", "species_113596" ] }, "reaction_10767486": { "compartment": "compartment_70101", "id": "reaction_10767486", "reactome": "R-SCE-200644", "name": "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_200739" ], "products": [ "species_70106", "species_29364", "species_200640" ], "modifiers": [ [ "species_10767483", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10773135": { "compartment": "compartment_12045", "id": "reaction_10773135", "reactome": "R-SCE-1482828", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2[4]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10773132", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "species_74016", "Q03674", "YMR006C" ] }, "reaction_10769054": { "compartment": "compartment_17951", "id": "reaction_10769054", "reactome": "R-SCE-390251", "name": "HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390248", "species_192307" ], "products": [ "species_193465", "species_390241", "species_192305" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10767494": { "compartment": "compartment_876", "id": "reaction_10767494", "reactome": "R-SCE-200646", "name": "Cytosolic folate export across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965" ], "products": [ "species_200716" ], "modifiers": [ [ "species_10767491", "catalyst" ] ], "additional_components": [ "YJL163C" ] }, "reaction_10768943": { "compartment": "compartment_17951", "id": "reaction_10768943", "reactome": "R-SCE-389639", "name": "phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389537", "species_389615", "species_113535" ], "products": [ "species_389594", "species_389583", "species_389536" ], "modifiers": [ [ "species_10768940", "catalyst" ] ], "additional_components": [ "P47181", "YJR154W", "species_111793" ] }, "reaction_10788342": { "compartment": "compartment_70101", "id": "reaction_10788342", "reactome": "R-SCE-9018877", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023708", "species_29356" ], "products": [ "species_9023712" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "species_158417", "Q10740", "YNL045W" ] }, "reaction_10763152": { "compartment": "compartment_70101", "id": "reaction_10763152", "reactome": "R-SCE-73608", "name": "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500829", "species_29356" ], "products": [ "species_31633", "species_500430" ], "modifiers": [ [ "species_10763149", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:15698", "CHEBI:16704", "CHEBI:16450", "species_158417", "Q06549", "YLR245C" ] }, "reaction_10772970": { "compartment": "compartment_12045", "id": "reaction_10772970", "reactome": "R-SCE-1482571", "name": "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498738", "species_29356" ], "products": [ "species_1524023", "species_1524021" ], "modifiers": [ [ "species_10772954", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10786551": { "compartment": "compartment_70101", "id": "reaction_10786551", "reactome": "R-SCE-8869606", "name": "NMRK1 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10786548", "catalyst" ] ], "additional_components": [ "YNL129W" ] }, "reaction_10773475": { "compartment": "compartment_876", "id": "reaction_10773475", "reactome": "R-SCE-1675810", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_1806240" ], "modifiers": [ [ "species_10773418", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10781631": { "compartment": "compartment_5460", "id": "reaction_10781631", "reactome": "R-SCE-5696091", "name": "ALDH1B1 tetramer oxidises CH3CHO to CH3COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_113532" ], "products": [ "species_113539", "species_29362", "species_113529" ], "modifiers": [ [ "species_10781628", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10770185": { "compartment": "compartment_17906", "id": "reaction_10770185", "reactome": "R-SCE-434382", "name": "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_3632881", "species_113592" ], "products": [ "species_111294", "species_76577", "species_200993" ], "modifiers": [ [ "species_10770182", "catalyst" ] ], "additional_components": [ "P47912", "YMR246W", "P39002", "YIL009W", "P30624", "YOR317W" ] }, "reaction_10767476": { "compartment": "compartment_70101", "id": "reaction_10767476", "reactome": "R-SCE-200555", "name": "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10764049", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "P32874", "YMR207C" ] }, "reaction_10782610": { "compartment": "compartment_5460", "id": "reaction_10782610", "reactome": "R-SCE-6792572", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781283", "species_10782600" ], "products": [ "species_10782602", "species_10781285" ], "modifiers": [ [ "species_10782607", "catalyst" ] ], "additional_components": [ "YAL044C", "P32473", "YBR221C", "species_29480", "P20967", "YIL125W", "CHEBI:17460", "P16387", "YER178W", "P09624", "YFL018C", "species_113596", "P19262", "YDR148C", "P12695", "YNL071W", "P32473", "YBR221C", "species_29480", "P20967", "YIL125W", "P16387", "YER178W", "CHEBI:17460", "P09624", "YFL018C", "species_113596", "P12695", "YNL071W", "P19262", "YDR148C", "YAL044C", "YJL046W" ] }, "reaction_10762216": { "compartment": "compartment_70101", "id": "reaction_10762216", "reactome": "R-SCE-71802", "name": "D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_29370", "species_30533" ], "modifiers": [ [ "species_10762213", "catalyst" ], [ "species_30533", "catalyst" ] ], "additional_components": [ "Q12471", "YOL136C", "Q06137", "YLR345W", "P32604", "YJL155C" ] }, "reaction_10773173": { "compartment": "compartment_12045", "id": "reaction_10773173", "reactome": "R-SCE-1482920", "name": "PG is hydrolyzed to 2-acyl LPG by PLA2[14]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498730", "species_1524021" ], "modifiers": [ [ "species_10773170", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10785552": { "compartment": "compartment_17963", "id": "reaction_10785552", "reactome": "R-SCE-8851225", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851224", "species_2022884" ], "products": [ "species_8851227", "species_425969", "species_8851226" ], "modifiers": [ [ "species_10785549", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58369", "species_110094", "species_110096", "species_109366", "species_109395", "species_109402", "species_113578", "P40009", "YER005W", "species_74016" ] }, "reaction_10765673": { "compartment": "compartment_7660", "id": "reaction_10765673", "reactome": "R-SCE-163743", "name": "Transcriptional activation of Acetyl-CoA carboxylase by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10765671" ], "modifiers": [], "additional_components": [ "Q00955", "YNR016C", "P32874", "YMR207C" ] }, "reaction_10784150": { "compartment": "compartment_5460", "id": "reaction_10784150", "reactome": "R-SCE-6801462", "name": "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6801458", "species_113521" ], "products": [ "species_5389850" ], "modifiers": [ [ "species_10784132", "catalyst" ] ], "additional_components": [ "YBR084W" ] }, "reaction_10769083": { "compartment": "compartment_17947", "id": "reaction_10769083", "reactome": "R-SCE-390393", "name": "Peroxisomal uptake of very long-chain fatty acyl CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390394" ], "products": [ "species_390260" ], "modifiers": [ [ "species_10768823", "catalyst" ] ], "additional_components": [ "P41909", "YPL147W" ] }, "reaction_10766760": { "compartment": "compartment_70101", "id": "reaction_10766760", "reactome": "R-SCE-191405", "name": "Two FPP molecules dimerize to form presqualene diphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191385" ], "products": [ "species_191265", "species_111294" ], "modifiers": [ [ "species_10766755", "catalyst" ] ], "additional_components": [ "P29704", "YHR190W", "species_109496" ] }, "reaction_10781904": { "compartment": "compartment_5460", "id": "reaction_10781904", "reactome": "R-SCE-6784224", "name": "PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784215" ], "products": [ "species_6784241" ], "modifiers": [ [ "species_10781901", "catalyst" ] ], "additional_components": [ "P09368", "YLR142W", "species_113596" ] }, "reaction_10763162": { "compartment": "compartment_70101", "id": "reaction_10763162", "reactome": "R-SCE-73647", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29494", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_110614", "species_29372" ], "modifiers": [ [ "species_10763159", "catalyst" ] ], "additional_components": [ "P28274", "YBL039C" ] }, "reaction_10786543": { "compartment": "compartment_70101", "id": "reaction_10786543", "reactome": "R-SCE-8869241", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_426639" ], "products": [ "species_426658", "species_426755" ], "modifiers": [ [ "species_10786540", "catalyst" ] ], "additional_components": [ "YOR022C" ] }, "reaction_10767496": { "compartment": "compartment_70101", "id": "reaction_10767496", "reactome": "R-SCE-200651", "name": "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_200739" ], "products": [ "species_200736", "species_197969" ], "modifiers": [ [ "species_10761810", "catalyst" ] ], "additional_components": [ "P37292", "YBR263W" ] }, "reaction_10777429": { "compartment": "compartment_17957", "id": "reaction_10777429", "reactome": "R-SCE-5250531", "name": "ARV1 transports CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193384" ], "products": [ "species_171095" ], "modifiers": [ [ "species_10777426", "catalyst" ] ], "additional_components": [ "YLR242C" ] }, "reaction_10767533": { "compartment": "compartment_876", "id": "reaction_10767533", "reactome": "R-SCE-200729", "name": "SLC46A1 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200716" ], "products": [ "species_197965" ], "modifiers": [ [ "species_10767491", "catalyst" ] ], "additional_components": [ "YJL163C" ] }, "reaction_10781613": { "compartment": "compartment_17906", "id": "reaction_10781613", "reactome": "R-SCE-5696074", "name": "AGK:Mg2+ phosphorylates MAG, DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696069", "species_5696066" ], "products": [ "species_5696026", "species_5696037" ], "modifiers": [ [ "species_10781610", "catalyst" ] ], "additional_components": [ "species_6797635", "species_6814795", "species_1602448", "species_417891", "Q12246", "YOR171C", "P47045", "TIM54", "species_109496", "Q06147", "YLR260W" ] }, "reaction_10788346": { "compartment": "compartment_70101", "id": "reaction_10788346", "reactome": "R-SCE-9020253", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024781", "species_29356" ], "products": [ "species_9024809" ], "modifiers": [ [ "species_10768259", "catalyst" ] ], "additional_components": [ "CHEBI:138649", "CHEBI:138648", "species_158417", "Q10740", "YNL045W" ] }, "reaction_10781648": { "compartment": "compartment_5460", "id": "reaction_10781648", "reactome": "R-SCE-5696839", "name": "MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_6801451", "species_113593" ], "products": [ "species_5389850", "species_113548", "species_113581" ], "modifiers": [ [ "species_10781645", "catalyst" ] ], "additional_components": [ "P07245", "YGR204W" ] }, "reaction_10784754": { "compartment": "compartment_70101", "id": "reaction_10784754", "reactome": "R-SCE-6809680", "name": "MTMR12 binds MTM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773463", "species_10784750" ], "products": [ "species_10784752" ], "modifiers": [], "additional_components": [ "YJR110W", "YJR110W", "P47147", "YJR110W" ] }, "reaction_10781641": { "compartment": "compartment_12045", "id": "reaction_10781641", "reactome": "R-SCE-5696448", "name": "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696449", "species_6782195" ], "products": [ "species_76194", "species_1500596" ], "modifiers": [ [ "species_10781638", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10789150": { "compartment": "compartment_70101", "id": "reaction_10789150", "reactome": "R-SCE-9695949", "name": "SPHK2 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_29370", "species_428203" ], "modifiers": [ [ "species_10769846", "catalyst" ], [ "species_10789148", "inhibitor" ] ], "additional_components": [ "Q12246", "YOR171C", "P47045", "TIM54", "Q06147", "YLR260W", "LigandDisplayForward?ligandId=6625", "Q12246", "YOR171C", "LigandDisplayForward?ligandId=10641", "P47045", "TIM54", "LigandDisplayForward?ligandId=10219", "LigandDisplayForward?ligandId=6624", "Q06147", "YLR260W" ] }, "reaction_10781989": { "compartment": "compartment_17951", "id": "reaction_10781989", "reactome": "R-SCE-6786720", "name": "DECR2 reduces LCtE-CoA to t3enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_113602", "species_6786723" ], "products": [ "species_389556", "species_6786715" ], "modifiers": [ [ "species_10781986", "catalyst" ] ], "additional_components": [ "YNL202W" ] }, "reaction_10773159": { "compartment": "compartment_12045", "id": "reaction_10773159", "reactome": "R-SCE-1482889", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_76194", "species_1500594" ], "modifiers": [ [ "species_10771182", "catalyst" ] ], "additional_components": [ "YOR245C" ] }, "reaction_10767517": { "compartment": "compartment_70616", "id": "reaction_10767517", "reactome": "R-SCE-200680", "name": "SLC25A32 transports THF from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111355" ], "products": [ "species_200671" ], "modifiers": [ [ "species_10767514", "catalyst" ] ], "additional_components": [ "YIL134W" ] }, "reaction_10768215": { "compartment": "compartment_70101", "id": "reaction_10768215", "reactome": "R-SCE-265295", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10768212", "catalyst" ] ], "additional_components": [ "YKL117W" ] }, "reaction_10774833": { "compartment": "compartment_70101", "id": "reaction_10774833", "reactome": "R-SCE-2993802", "name": "HLCS biotinylates PC:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_10774820", "species_113592" ], "products": [ "species_10774825", "species_111294", "species_76577" ], "modifiers": [ [ "species_10774830", "catalyst" ] ], "additional_components": [ "P11154", "YGL062W", "species_113527", "P11154", "YGL062W", "species_113527", "YDL141W" ] }, "reaction_10781981": { "compartment": "compartment_70101", "id": "reaction_10781981", "reactome": "R-SCE-6786650", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_29356" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10781978", "catalyst" ] ], "additional_components": [ "Q12204", "YOR022C" ] }, "reaction_10773485": { "compartment": "compartment_12045", "id": "reaction_10773485", "reactome": "R-SCE-1675813", "name": "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_29370", "species_1806234" ], "modifiers": [ [ "species_10773482", "catalyst" ] ], "additional_components": [ "P37297", "YLR305C", "P42951", "YJL100W" ] }, "reaction_10786556": { "compartment": "compartment_70101", "id": "reaction_10786556", "reactome": "R-SCE-8869607", "name": "NMRK2 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10786553", "catalyst" ] ], "additional_components": [ "YNL129W" ] }, "reaction_10761919": { "compartment": "compartment_5460", "id": "reaction_10761919", "reactome": "R-SCE-71397", "name": "lipo-PDH decarboxylates PYR to Ac-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113557", "species_113526" ], "products": [ "species_29376", "species_29362", "species_113559" ], "modifiers": [ [ "species_10761916", "catalyst" ] ], "additional_components": [ "P32473", "YBR221C", "species_29480", "P16387", "YER178W", "P09624", "YFL018C", "species_113596", "P12695", "YNL071W" ] }, "reaction_10762130": { "compartment": "compartment_70101", "id": "reaction_10762130", "reactome": "R-SCE-71707", "name": "ethanol + NAD+ => acetaldehyde + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30203", "species_29360" ], "products": [ "species_70106", "species_73473", "species_29510" ], "modifiers": [ [ "species_10762127", "catalyst" ] ], "additional_components": [ "species_158417", "P32771", "YDL168W" ] }, "reaction_10773425": { "compartment": "compartment_876", "id": "reaction_10773425", "reactome": "R-SCE-1675773", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_202247" ], "products": [ "species_29370", "species_179838" ], "modifiers": [ [ "species_10773418", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10773535": { "compartment": "compartment_171062", "id": "reaction_10773535", "reactome": "R-SCE-1675939", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806200" ], "modifiers": [ [ "species_10773532", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "species_113527" ] }, "reaction_10773153": { "compartment": "compartment_12045", "id": "reaction_10773153", "reactome": "R-SCE-1482867", "name": "DLCL is acylated to MLCL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524080", "species_1500578" ], "products": [ "species_76194", "species_1524069" ], "modifiers": [ [ "species_10764105", "catalyst" ] ], "additional_components": [ "YBR042C" ] }, "reaction_10767135": { "compartment": "compartment_70101", "id": "reaction_10767135", "reactome": "R-SCE-198563", "name": "IDO1 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29500" ], "products": [ "species_33179" ], "modifiers": [ [ "species_10767132", "catalyst" ] ], "additional_components": [ "P47125", "YJR078W", "species_189444" ] }, "reaction_10769042": { "compartment": "compartment_17951", "id": "reaction_10769042", "reactome": "R-SCE-389986", "name": "trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389894", "species_141343" ], "products": [ "species_389982" ], "modifiers": [ [ "species_10766831", "catalyst" ] ], "additional_components": [ "Q02207", "YKR009C" ] }, "reaction_10773514": { "compartment": "compartment_876", "id": "reaction_10773514", "reactome": "R-SCE-1675836", "name": "PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806276", "species_29372" ], "modifiers": [ [ "species_10773511", "catalyst" ] ], "additional_components": [ "Q12271", "YOR109W", "P40559", "YIL002C", "Q08227", "YOL065C", "P50942", "YNL106C" ] }, "reaction_10766591": { "compartment": "compartment_5460", "id": "reaction_10766591", "reactome": "R-SCE-189465", "name": "FECH binds Fe2+ to PRIN9 to form heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189487", "species_113531" ], "products": [ "species_189444", "species_113529" ], "modifiers": [ [ "species_10766588", "catalyst" ], [ "species_391232", "inhibitor" ] ], "additional_components": [ "P16622", "YOR176W" ] }, "reaction_10766702": { "compartment": "compartment_70101", "id": "reaction_10766702", "reactome": "R-SCE-191303", "name": "FDPS dimer transfers IPPP to GPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191409" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10766699", "catalyst" ] ], "additional_components": [ "P08524", "YJL167W", "species_109496" ] }, "reaction_10786562": { "compartment": "compartment_70101", "id": "reaction_10786562", "reactome": "R-SCE-8869633", "name": "NMRK1 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_70106", "species_29370", "species_8869353" ], "modifiers": [ [ "species_10786548", "catalyst" ] ], "additional_components": [ "YNL129W" ] }, "reaction_10766720": { "compartment": "compartment_70101", "id": "reaction_10766720", "reactome": "R-SCE-191352", "name": "HMGCR dimer reduces bHMG-CoA to MVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191374" ], "products": [ "species_76194", "species_29366", "species_191424" ], "modifiers": [ [ "species_10766717", "catalyst" ] ], "additional_components": [ "P12683", "YML075C" ] }, "reaction_10767740": { "compartment": "compartment_20699", "id": "reaction_10767740", "reactome": "R-SCE-203700", "name": "eNOS translocation from Golgi to Caveolae", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767716" ], "products": [ "species_10767589" ], "modifiers": [], "additional_components": [ "YHR042W", "species_158417", "species_73524", "species_189444", "P16603", "YHR042W", "species_113596" ] }, "reaction_10772965": { "compartment": "compartment_70616", "id": "reaction_10772965", "reactome": "R-SCE-1482546", "name": "2-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524047", "species_1524038" ], "products": [ "species_1524042", "species_29374" ], "modifiers": [ [ "species_10772962", "catalyst" ] ], "additional_components": [ "YDL142C" ] }, "reaction_10769833": { "compartment": "compartment_70101", "id": "reaction_10769833", "reactome": "R-SCE-428185", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428163", "species_428139" ], "products": [ "species_76194", "species_428126" ], "modifiers": [ [ "species_10769830", "catalyst" ] ], "additional_components": [ "P38703", "YHL003C", "P28496", "YKL008C" ] }, "reaction_10787624": { "compartment": "compartment_5460", "id": "reaction_10787624", "reactome": "R-SCE-8952873", "name": "MECR dimer reduces tdec2-CoA to DEC-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_77343", "species_113529" ], "products": [ "species_113563", "species_77308" ], "modifiers": [ [ "species_10787621", "catalyst" ] ], "additional_components": [ "P38071", "YBR026C" ] }, "reaction_10786524": { "compartment": "compartment_12045", "id": "reaction_10786524", "reactome": "R-SCE-8867876", "name": "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_392417" ], "products": [ "species_1806234", "species_33625" ], "modifiers": [ [ "species_10786521", "catalyst" ] ], "additional_components": [ "P38755", "YHR001W", "P35844", "YPL145C", "P35843", "YOR237W" ] }, "reaction_10769008": { "compartment": "compartment_17951", "id": "reaction_10769008", "reactome": "R-SCE-389826", "name": "glyoxylate + NADPH + H+ => glycolate + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_113602", "species_389678" ], "products": [ "species_389822", "species_389556" ], "modifiers": [ [ "species_10769005", "catalyst" ] ], "additional_components": [ "YPL113C" ] }, "reaction_10785535": { "compartment": "compartment_984", "id": "reaction_10785535", "reactome": "R-SCE-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8936166" ], "products": [ "species_109277", "species_351626", "species_8851092" ], "modifiers": [ [ "species_10785532", "catalyst" ] ], "additional_components": [ "species_29494", "species_113592", "species_2509836", "species_29438", "species_110614", "species_29420", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10786911": { "compartment": "compartment_70101", "id": "reaction_10786911", "reactome": "R-SCE-8876889", "name": "Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10767435", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "Q00955", "YNR016C", "species_113527" ] }, "reaction_10769786": { "compartment": "compartment_70101", "id": "reaction_10769786", "reactome": "R-SCE-428123", "name": "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_428182" ], "products": [ "species_29366", "species_428163" ], "modifiers": [ [ "species_10769783", "catalyst" ] ], "additional_components": [ "YBR265W" ] }, "reaction_10785504": { "compartment": "compartment_984", "id": "reaction_10785504", "reactome": "R-SCE-8850846", "name": "NTPDase1 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277", "species_351626" ], "modifiers": [ [ "species_10785501", "catalyst" ] ], "additional_components": [ "P40009", "YER005W", "species_74016", "species_109496" ] }, "reaction_10761841": { "compartment": "compartment_70101", "id": "reaction_10761841", "reactome": "R-SCE-71296", "name": "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31467", "species_29356" ], "products": [ "species_29996" ], "modifiers": [ [ "species_10761838", "catalyst" ] ], "additional_components": [ "YHR163W" ] }, "reaction_10776243": { "compartment": "compartment_70101", "id": "reaction_10776243", "reactome": "R-SCE-3780997", "name": "PPP1R3C binds to glycogen:GYG2:GYS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775586", "species_10776211" ], "products": [ "species_10776213" ], "modifiers": [], "additional_components": [ "P47011", "YJL137C", "P27472", "YLR258W", "species_109496", "P23337", "YFR015C", "P40187", "YIL045W", "P40036", "YER054C", "Q06216", "YLR273C", "P28006", "YOR178C", "P40187", "YIL045W", "P40036", "YER054C", "P47011", "YJL137C", "P27472", "YLR258W", "Q06216", "YLR273C", "P28006", "YOR178C", "species_109496", "P23337", "YFR015C" ] }, "reaction_10778265": { "compartment": "compartment_7660", "id": "reaction_10778265", "reactome": "R-SCE-5649799", "name": "DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10778250" ], "products": [ "species_10778263", "species_77502" ], "modifiers": [ [ "species_10778255", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YDR440W" ] }, "reaction_10775068": { "compartment": "compartment_7660", "id": "reaction_10775068", "reactome": "R-SCE-3215385", "name": "CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775059" ], "products": [ "species_10775065" ], "modifiers": [ [ "species_10775059", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10778269": { "compartment": "compartment_7660", "id": "reaction_10778269", "reactome": "R-SCE-5649801", "name": "DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_77502", "species_10778245" ], "modifiers": [ [ "species_10778255", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YDR440W" ] }, "reaction_10776189": { "compartment": "compartment_7660", "id": "reaction_10776189", "reactome": "R-SCE-3777129", "name": "HDAC3 containing complexes deacetylate histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10776109" ], "products": [ "species_5566518", "species_10776115" ], "modifiers": [ [ "species_10776186", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "CHEBI:57627", "P53096", "YGL194C", "P38262", "YBR103W", "P25357", "YCR033W" ] }, "reaction_10777324": { "compartment": "compartment_7660", "id": "reaction_10777324", "reactome": "R-SCE-5225649", "name": "RBBP7 binds histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_10775913" ], "products": [ "species_10777322" ], "modifiers": [ [ "species_10777305", "inhibitor" ] ], "additional_components": [ "P36012", "YKL049C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P39984", "YEL056W", "Q12363", "YOR230W", "P13712", "YBR195C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P39984", "YEL056W", "Q12363", "YOR230W", "P36012", "YKL049C", "P13712", "YBR195C", "P36012", "YKL049C" ] }, "reaction_10778200": { "compartment": "compartment_7660", "id": "reaction_10778200", "reactome": "R-SCE-5637686", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775017", "species_77087" ], "products": [ "species_77502", "species_10776782" ], "modifiers": [ [ "species_10778197", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P46995", "YJL168C", "P38827", "YHR119W", "P43132", "YLR015W", "P36124", "YKR029C", "Q12529", "YPL165C", "P39706", "YAR003W", "Q12504", "YDR257C", "P38222", "YBR030W", "P38123", "YBR175W" ] }, "reaction_10777042": { "compartment": "compartment_7660", "id": "reaction_10777042", "reactome": "R-SCE-5205798", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10763701", "species_77087" ], "products": [ "species_10777039", "species_77502" ], "modifiers": [ [ "species_10775032", "catalyst" ] ], "additional_components": [ "YBR009C", "YBR009C", "YBR034C" ] }, "reaction_10777010": { "compartment": "compartment_7660", "id": "reaction_10777010", "reactome": "R-SCE-5159245", "name": "SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_10775017", "species_77502" ], "modifiers": [ [ "species_10777007", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P46995", "YJL168C", "P38827", "YHR119W", "P43132", "YLR015W", "P36124", "YKR029C", "P39706", "YAR003W", "Q12504", "YDR257C", "P38123", "YBR175W", "P38222", "YBR030W" ] }, "reaction_10777320": { "compartment": "compartment_7660", "id": "reaction_10777320", "reactome": "R-SCE-5225602", "name": "WDR5 binds Me2sR3-replicative histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777305", "species_10776991" ], "products": [ "species_10777318" ], "modifiers": [], "additional_components": [ "P36012", "YKL049C", "YBR175W", "P36012", "YKL049C", "P38123", "YBR175W" ] }, "reaction_10777047": { "compartment": "compartment_7660", "id": "reaction_10777047", "reactome": "R-SCE-5205799", "name": "CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_77502", "species_10775241" ], "modifiers": [ [ "species_10775065", "catalyst" ], [ "species_10777045", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W", "Q06488", "YLR357W", "P43609", "YFR037C", "P38274", "YBR133C", "P22082", "YOR290C", "P80428", "YJL081C", "P32597", "YIL126W", "P25632", "YCR052W", "Q12406", "YPR034W", "P53628", "YNR023W", "Q05123", "YMR033W", "Q06168", "YLR321C", "P32591", "YJL176C" ] }, "reaction_10778587": { "compartment": "compartment_7660", "id": "reaction_10778587", "reactome": "R-SCE-5661117", "name": "CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10775241" ], "products": [ "species_10778585", "species_77502" ], "modifiers": [ [ "species_10775065", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P13365", "YAL040C", "P20438", "YPL256C", "P38274", "YBR133C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P36005", "YKL161C", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10776165": { "compartment": "compartment_7660", "id": "reaction_10776165", "reactome": "R-SCE-3769447", "name": "HDAC1:2-containing complex deacetylate histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10776109" ], "products": [ "species_5566518", "species_10776115" ], "modifiers": [ [ "species_10776160", "catalyst" ], [ "species_10776163", "inhibitor" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P09547", "YPL016W", "Q12206", "YOR229W", "Q03010", "YPL139C", "Q03124", "YML127W", "P40505", "YIL084C", "P39984", "YEL056W", "Q12363", "YOR230W", "P13712", "YBR195C", "P31385", "YAL013W", "P38429", "YMR263W", "Q12214", "YPR068C", "LigandDisplayForward?ligandId=7489", "P09547", "YPL016W", "Q03124", "YML127W", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "P39984", "YEL056W", "LigandDisplayForward?ligandId=6852", "P31385", "YAL013W", "LigandDisplayForward?ligandId=7496", "Q12214", "YPR068C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P40505", "YIL084C", "Q12363", "YOR230W", "P13712", "YBR195C", "P38429", "YMR263W" ] }, "reaction_10777211": { "compartment": "compartment_7660", "id": "reaction_10777211", "reactome": "R-SCE-5205867", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777175", "species_77087" ], "products": [ "species_77502", "species_10777209" ], "modifiers": [ [ "species_10775032", "catalyst" ] ], "additional_components": [ "P04912", "YBL003C", "P04911", "YDR225W", "P04912", "YBL003C", "P04911", "YDR225W", "YBR034C" ] }, "reaction_10778258": { "compartment": "compartment_7660", "id": "reaction_10778258", "reactome": "R-SCE-5649764", "name": "DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10778245" ], "products": [ "species_77502", "species_10778250" ], "modifiers": [ [ "species_10778255", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YDR440W" ] }, "reaction_10778598": { "compartment": "compartment_7660", "id": "reaction_10778598", "reactome": "R-SCE-5661126", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777039", "species_77087" ], "products": [ "species_10778596", "species_77502" ], "modifiers": [ [ "species_10775032", "catalyst" ] ], "additional_components": [ "YBR009C", "YBR009C", "YBR034C" ] }, "reaction_10778237": { "compartment": "compartment_7660", "id": "reaction_10778237", "reactome": "R-SCE-5638157", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776742", "species_77087" ], "products": [ "species_10778230", "species_77502" ], "modifiers": [ [ "species_10776872", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P46995", "YJL168C", "Q12529", "YPL165C", "P38890", "YHR207C" ] }, "reaction_10776851": { "compartment": "compartment_7660", "id": "reaction_10776851", "reactome": "R-SCE-4827382", "name": "SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10776759" ], "products": [ "species_10776843", "species_77502" ], "modifiers": [ [ "species_10776848", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YHR119W" ] }, "reaction_10778273": { "compartment": "compartment_7660", "id": "reaction_10778273", "reactome": "R-SCE-5649802", "name": "WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10776818" ], "products": [ "species_10778271", "species_77502" ], "modifiers": [ [ "species_10776856", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YJL168C" ] }, "reaction_10776875": { "compartment": "compartment_7660", "id": "reaction_10776875", "reactome": "R-SCE-4827383", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_10776742", "species_77502" ], "modifiers": [ [ "species_10776872", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P46995", "YJL168C", "Q12529", "YPL165C", "P38890", "YHR207C" ] }, "reaction_10777413": { "compartment": "compartment_7660", "id": "reaction_10777413", "reactome": "R-SCE-5244692", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10776782" ], "products": [ "species_10777406", "species_77502" ], "modifiers": [ [ "species_10777410", "catalyst" ], [ "species_10777134", "inhibitor" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "P38827", "YHR119W", "P43132", "YLR015W", "P36124", "YKR029C", "Q12529", "YPL165C", "P39706", "YAR003W", "P38123", "YBR175W", "P36012", "YKL049C" ] }, "reaction_10789077": { "compartment": "compartment_7660", "id": "reaction_10789077", "reactome": "R-SCE-9679787", "name": "HDAC1:2-containing complex binds HDAC2 Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776160", "species_9679795" ], "products": [ "species_10776163" ], "modifiers": [], "additional_components": [ "P09547", "YPL016W", "Q12206", "YOR229W", "Q03010", "YPL139C", "Q03124", "YML127W", "P40505", "YIL084C", "P39984", "YEL056W", "Q12363", "YOR230W", "P13712", "YBR195C", "P31385", "YAL013W", "P38429", "YMR263W", "Q12214", "YPR068C", "LigandDisplayForward?ligandId=7489", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "LigandDisplayForward?ligandId=6852", "LigandDisplayForward?ligandId=7496", "LigandDisplayForward?ligandId=7489", "P09547", "YPL016W", "Q03124", "YML127W", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "P39984", "YEL056W", "LigandDisplayForward?ligandId=6852", "P31385", "YAL013W", "LigandDisplayForward?ligandId=7496", "Q12214", "YPR068C", "Q12206", "YOR229W", "Q03010", "YPL139C", "P40505", "YIL084C", "Q12363", "YOR230W", "P13712", "YBR195C", "P38429", "YMR263W" ] }, "reaction_10778240": { "compartment": "compartment_7660", "id": "reaction_10778240", "reactome": "R-SCE-5638333", "name": "WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775019", "species_77087" ], "products": [ "species_10776823", "species_77502" ], "modifiers": [ [ "species_10776856", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YJL168C" ] }, "reaction_10778267": { "compartment": "compartment_7660", "id": "reaction_10778267", "reactome": "R-SCE-5649800", "name": "WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10776823" ], "products": [ "species_77502", "species_10776818" ], "modifiers": [ [ "species_10776856", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YJL168C" ] }, "reaction_10776286": { "compartment": "compartment_7660", "id": "reaction_10776286", "reactome": "R-SCE-3782655", "name": "HDAC10 deacetylates histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10776109" ], "products": [ "species_5566518", "species_10776115" ], "modifiers": [ [ "species_10776283", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "P04912", "YBL003C", "P04911", "YDR225W", "YNL021W" ] }, "reaction_10778195": { "compartment": "compartment_70101", "id": "reaction_10778195", "reactome": "R-SCE-5634802", "name": "MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778184", "species_71284" ], "products": [ "species_71285", "species_10778188" ], "modifiers": [ [ "species_10778190", "catalyst" ] ], "additional_components": [ "P36012", "YKL049C", "P36012", "YKL049C", "YDR216W" ] }, "reaction_10782722": { "compartment": "compartment_876", "id": "reaction_10782722", "reactome": "R-SCE-6797630", "name": "LRPP4(LRPP1-3,5) hydrolyse LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_417891", "species_109276" ], "products": [ "species_6797635", "species_109277" ], "modifiers": [ [ "species_10782719", "catalyst" ] ], "additional_components": [ "Q05521", "YDR284C", "Q04396", "YDR503C" ] }, "reaction_10769347": { "compartment": "compartment_876", "id": "reaction_10769347", "reactome": "R-SCE-418574", "name": "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769184" ], "products": [ "species_10769344" ], "modifiers": [ [ "species_10769184", "catalyst" ] ], "additional_components": [ "species_29438", "P10823", "YER020W", "species_111349", "P10823", "YER020W", "species_29438", "P10823", "YER020W" ] }, "reaction_10769393": { "compartment": "compartment_70101", "id": "reaction_10769393", "reactome": "R-SCE-419166", "name": "GEFs activate RhoA,B,C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10769303" ], "products": [ "species_10769305", "species_29420" ], "modifiers": [ [ "species_10769390", "catalyst" ] ], "additional_components": [ "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_111349", "Q00245", "YIL118W", "Q00246", "YKR055W", "P06781", "YNL090W", "P06780", "YPR165W", "species_29438", "Q05670", "YMR232W", "P04821", "YLR310C", "P34216", "YBL047C", "P07866", "YAL024C", "P25300", "YCR038C" ] }, "reaction_10769338": { "compartment": "compartment_70101", "id": "reaction_10769338", "reactome": "R-SCE-418553", "name": "cAMP degradation by Phosphodiesterases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_29356" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10769330", "catalyst" ] ], "additional_components": [ "YOR360C" ] }, "reaction_10770069": { "compartment": "compartment_70101", "id": "reaction_10770069", "reactome": "R-SCE-429860", "name": "DCP1-DCP2 complex decaps mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770038", "species_29356" ], "products": [ "species_430004", "species_10770040" ], "modifiers": [ [ "species_10770066", "catalyst" ] ], "additional_components": [ "P25644", "YCR077C", "P40070", "YER112W", "P57743", "YLR438C-A", "P53905", "YNL147W", "P40089", "YER146W", "P47017", "YJL124C", "Q06406", "YDR378C", "P38203", "YBL026W", "P25644", "YCR077C", "P40070", "YER112W", "P57743", "YLR438C-A", "P53905", "YNL147W", "P40089", "YER146W", "P47017", "YJL124C", "Q06406", "YDR378C", "P38203", "YBL026W", "P39517", "YDL160C", "P53550", "YNL118C", "P39998", "YEL015W", "Q12517", "YOL149W" ] }, "reaction_10770142": { "compartment": "compartment_70101", "id": "reaction_10770142", "reactome": "R-SCE-430028", "name": "Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429974", "species_29356" ], "products": [ "species_109395", "species_109402", "species_429926", "species_76577", "species_113578" ], "modifiers": [ [ "species_10770139", "catalyst" ] ], "additional_components": [ "Q02793", "SKI8", "P53859", "CSL4", "Q08285", "RRP40", "Q12277", "RRP42", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "P35207", "SKI2", "P53256", "RRP46", "P38792", "RRP4", "P48240", "MTR3", "Q08162", "DIS3", "P17883", "SKI3" ] }, "reaction_10770077": { "compartment": "compartment_70101", "id": "reaction_10770077", "reactome": "R-SCE-429961", "name": "DCPS scavenges the 7-methylguanosine cap of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429926", "species_29356" ], "products": [ "species_429925", "species_430042" ], "modifiers": [ [ "species_10770074", "catalyst" ] ], "additional_components": [ "YLR270W" ] }, "reaction_10770079": { "compartment": "compartment_70101", "id": "reaction_10770079", "reactome": "R-SCE-429978", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429974", "species_10770036" ], "products": [ "species_10770038" ], "modifiers": [], "additional_components": [ "P25644", "YCR077C", "P40070", "YER112W", "P57743", "YLR438C-A", "P53905", "YNL147W", "P40089", "YER146W", "P47017", "YJL124C", "Q06406", "YDR378C", "P38203", "YBL026W", "P25644", "YCR077C", "P40070", "YER112W", "P57743", "YLR438C-A", "P53905", "YNL147W", "P40089", "YER146W", "P47017", "YJL124C", "Q06406", "YDR378C", "P38203", "YBL026W" ] }, "reaction_10771594": { "compartment": "compartment_876", "id": "reaction_10771594", "reactome": "R-SCE-917870", "name": "SLC46A1 transports hemes from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310" ], "products": [ "species_9707308" ], "modifiers": [ [ "species_10767491", "catalyst" ] ], "additional_components": [ "species_189444", "CHEBI:36144", "species_189444", "CHEBI:36144", "YJL163C" ] }, "reaction_10769319": { "compartment": "compartment_876", "id": "reaction_10769319", "reactome": "R-SCE-418309", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016" ], "products": [ "species_74112" ], "modifiers": [ [ "species_10769310", "catalyst" ] ], "additional_components": [ "YGL006W" ] }, "reaction_10777836": { "compartment": "compartment_70101", "id": "reaction_10777836", "reactome": "R-SCE-5578910", "name": "KCNK dimers transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10777833", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10777914": { "compartment": "compartment_876", "id": "reaction_10777914", "reactome": "R-SCE-5617178", "name": "ATP2B4 binds to NOS1, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769316", "species_10769321" ], "products": [ "species_10777912" ], "modifiers": [], "additional_components": [ "YGL006W", "YHR042W", "P16603", "YHR042W", "P38929", "YGL006W" ] }, "reaction_10789363": { "compartment": "compartment_7660", "id": "reaction_10789363", "reactome": "R-SCE-9757256", "name": "MCM3 binds MCM5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760359", "species_10760355" ], "products": [ "species_10760361" ], "modifiers": [], "additional_components": [ "P24279", "MCM3", "P29496", "MCM5" ] }, "reaction_10789309": { "compartment": "compartment_7660", "id": "reaction_10789309", "reactome": "R-SCE-9749197", "name": "ORC1 binds to H4K20me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789305", "species_10760200" ], "products": [ "species_10789307" ], "modifiers": [], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "P54784", "phospho-ORC1", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W" ] }, "reaction_10789288": { "compartment": "compartment_70101", "id": "reaction_10789288", "reactome": "R-SCE-9734730", "name": "ORC1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10789286" ], "products": [ "species_10760200" ], "modifiers": [], "additional_components": [] }, "reaction_10789367": { "compartment": "compartment_7660", "id": "reaction_10789367", "reactome": "R-SCE-9757258", "name": "MCM2 binds MCM4:MCM6:MCM7 heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760349", "species_10760335" ], "products": [ "species_10760351" ], "modifiers": [], "additional_components": [ "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6" ] }, "reaction_10760180": { "compartment": "compartment_7660", "id": "reaction_10760180", "reactome": "R-SCE-68595", "name": "ORC2 binds ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760176", "species_10760172" ], "products": [ "species_10760178" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P54790", "ORC3" ] }, "reaction_10760188": { "compartment": "compartment_7660", "id": "reaction_10760188", "reactome": "R-SCE-68603", "name": "ORC5 binds ORC2:ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760178", "species_10760184" ], "products": [ "species_10760186" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P54790", "ORC3", "P32833", "ORC2", "P50874", "ORC5", "P54790", "ORC3" ] }, "reaction_10760196": { "compartment": "compartment_7660", "id": "reaction_10760196", "reactome": "R-SCE-68610", "name": "Formation of ORC(2-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760192", "species_10760186" ], "products": [ "species_10760194" ], "modifiers": [ [ "species_29358", "catalyst" ] ], "additional_components": [ "P32833", "ORC2", "P50874", "ORC5", "P54790", "ORC3", "P32833", "ORC2", "P54791", "ORC4", "P50874", "ORC5", "P54790", "ORC3" ] }, "reaction_10760222": { "compartment": "compartment_7660", "id": "reaction_10760222", "reactome": "R-SCE-68688", "name": "CDC6 association with ORC(1-6) at replication origins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760214", "species_10760218" ], "products": [ "species_10760220" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P54791", "ORC4", "P54784", "phospho-ORC1", "P50874", "ORC5", "P54790", "ORC3", "P32833", "ORC2", "P54791", "ORC4", "P54784", "phospho-ORC1", "P09119", "CDC6", "P50874", "ORC5", "P54790", "ORC3" ] }, "reaction_10789311": { "compartment": "compartment_7660", "id": "reaction_10789311", "reactome": "R-SCE-9749253", "name": "Formation of MCM2-7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760361", "species_10760351" ], "products": [ "species_10760363" ], "modifiers": [], "additional_components": [ "P24279", "MCM3", "P29496", "MCM5", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P24279", "MCM3", "P29469", "MCM2", "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6", "P29496", "MCM5" ] }, "reaction_10789365": { "compartment": "compartment_7660", "id": "reaction_10789365", "reactome": "R-SCE-9757257", "name": "MCM4, MCM6 and MCM7 form a heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760343", "species_10760347", "species_10760339" ], "products": [ "species_10760349" ], "modifiers": [], "additional_components": [ "P38132", "MCM7", "P30665", "MCM4", "P53091", "MCM6" ] }, "reaction_10760210": { "compartment": "compartment_7660", "id": "reaction_10760210", "reactome": "R-SCE-68611", "name": "Formation of ORC(1-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760194", "species_10760204" ], "products": [ "species_10760208" ], "modifiers": [], "additional_components": [ "P32833", "ORC2", "P54791", "ORC4", "P50874", "ORC5", "P54790", "ORC3", "P54784", "phospho-ORC1", "P32833", "ORC2", "P54791", "ORC4", "P54784", "phospho-ORC1", "P50874", "ORC5", "P54790", "ORC3" ] }, "reaction_10784856": { "compartment": "compartment_7660", "id": "reaction_10784856", "reactome": "R-SCE-6810376", "name": "ING2 binds PI5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776424", "species_6810408" ], "products": [ "species_10784854" ], "modifiers": [], "additional_components": [ "Q08465", "YOR064C", "P50947", "YNL097C", "P38806", "YHR090C", "Q08465", "YOR064C", "species_1806240", "P50947", "YNL097C", "P38806", "YHR090C" ] }, "reaction_10786979": { "compartment": "compartment_7660", "id": "reaction_10786979", "reactome": "R-SCE-8877692", "name": "PIN1 binds phosphorylated PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786972", "species_10771753" ], "products": [ "species_10786977" ], "modifiers": [], "additional_components": [ "P38994", "YDR208W", "YJR017C", "P38994", "YDR208W", "P22696", "YJR017C" ] }, "reaction_10786975": { "compartment": "compartment_7660", "id": "reaction_10786975", "reactome": "R-SCE-8877691", "name": "MAP2K6 phosphorylates PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10786961" ], "products": [ "species_113582", "species_10786972" ], "modifiers": [ [ "species_10770703", "catalyst" ] ], "additional_components": [ "P38994", "YDR208W", "P38994", "YDR208W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10764546": { "compartment": "compartment_70101", "id": "reaction_10764546", "reactome": "R-SCE-109702", "name": "PDPK1 phosphorylates AKT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10764531" ], "products": [ "species_29370", "species_10764543" ], "modifiers": [ [ "species_10764515", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "P12688", "YKL126W", "species_179838", "P11792", "YHR205W", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10764517": { "compartment": "compartment_876", "id": "reaction_10764517", "reactome": "R-SCE-109701", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10764513" ], "products": [ "species_10764515" ], "modifiers": [], "additional_components": [ "YOL100W", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10772818": { "compartment": "compartment_70101", "id": "reaction_10772818", "reactome": "R-SCE-1358791", "name": "Phosphorylation of USP8 by P-AKT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772805", "species_113592" ], "products": [ "species_29370", "species_10772816" ], "modifiers": [ [ "species_10767105", "catalyst" ] ], "additional_components": [ "P39538", "YJL197W", "P32571", "YDR069C", "P39944", "YER144C", "P39538", "YJL197W", "P32571", "YDR069C", "P39944", "YER144C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10768224": { "compartment": "compartment_984", "id": "reaction_10768224", "reactome": "R-SCE-265456", "name": "NPC1L1 binds ezetimibe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265479", "species_10768220" ], "products": [ "species_10768222" ], "modifiers": [], "additional_components": [ "YPL006W", "species_265479", "Q12200", "YPL006W" ] }, "reaction_10777748": { "compartment": "compartment_70101", "id": "reaction_10777748", "reactome": "R-SCE-5362564", "name": "ADH1A,1C,4 oxidise atROL to atRAL in vitro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_73473", "species_975622" ], "modifiers": [ [ "species_10777745", "catalyst" ] ], "additional_components": [ "species_158417", "P32771", "YDL168W" ] }, "reaction_10777718": { "compartment": "compartment_70101", "id": "reaction_10777718", "reactome": "R-SCE-5362518", "name": "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_73473", "species_975622" ], "modifiers": [ [ "species_10777715", "catalyst" ] ], "additional_components": [ "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C" ] }, "reaction_10777743": { "compartment": "compartment_70101", "id": "reaction_10777743", "reactome": "R-SCE-5362522", "name": "ALDHs oxidise atRAL to atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975622", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_5334816" ], "modifiers": [ [ "species_10777740", "catalyst" ] ], "additional_components": [ "P40047", "YER073W", "P46367", "YOR374W", "P54115", "YPL061W" ] }, "reaction_10777778": { "compartment": "compartment_70101", "id": "reaction_10777778", "reactome": "R-SCE-5419165", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_975622" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10777775", "catalyst" ] ], "additional_components": [ "P34251", "YNL181W", "Q08651", "YOR246C", "Q06417", "YLR426W", "Q07530", "YDL114W", "Q03085", "YPL033C", "P53878", "YNL181W" ] }, "reaction_10784158": { "compartment": "compartment_7660", "id": "reaction_10784158", "reactome": "R-SCE-6802973", "name": "PLK3 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10763791" ], "products": [ "species_113582", "species_10784153" ], "modifiers": [ [ "species_10784155", "catalyst" ] ], "additional_components": [ "YMR036C", "YMR036C", "YMR001C" ] }, "reaction_10766925": { "compartment": "compartment_876", "id": "reaction_10766925", "reactome": "R-SCE-196017", "name": "Dynamin is recruited to the gap junction plaque", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10766678", "species_10766651" ], "products": [ "species_10766680" ], "modifiers": [], "additional_components": [ "P54861", "YLL001W", "P21576", "YKR001C", "P32266", "YOR211C", "P60010", "YFL039C", "P17891", "YGR167W", "Q99186", "YOL062C", "P22137", "YGL206C", "P60010", "YFL039C", "P54861", "YLL001W", "P17891", "YGR167W", "P21576", "YKR001C", "P32266", "YOR211C", "Q99186", "YOL062C", "P22137", "YGL206C" ] }, "reaction_10788439": { "compartment": "compartment_17947", "id": "reaction_10788439", "reactome": "R-SCE-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788429" ], "products": [ "species_10787654", "species_10788437" ], "modifiers": [], "additional_components": [ "P15202", "YDR256C", "P32573", "YNL202W", "P53112", "PEX14", "P32796", "YML042W", "P21954", "YDL066W", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P13711", "YGL205W", "Q12524", "YLR151C", "Q02207", "YKR009C", "P80667", "PEX13", "P16603", "YHR042W", "Q04370", "YMR026C", "Q06010", "YLR389C", "P31787", "YGR037C", "P39994", "YEL020C", "P00175", "CYB2", "P41903", "YJR019C", "P35056", "phospho-PEX5", "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "Q05568", "YDR265W", "P15202", "YDR256C", "P32573", "YNL202W", "P13711", "YGL205W", "Q12524", "YLR151C", "Q02207", "YKR009C", "P32796", "YML042W", "P21954", "YDL066W", "P16603", "YHR042W", "Q06010", "YLR389C", "P31787", "YGR037C", "P39994", "YEL020C", "P00175", "CYB2", "P41903", "YJR019C" ] }, "reaction_10788389": { "compartment": "compartment_70101", "id": "reaction_10788389", "reactome": "R-SCE-9033232", "name": "PEX7 binds cargo proteins containing PTS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788385", "species_10788379" ], "products": [ "species_10788387" ], "modifiers": [], "additional_components": [ "P47181", "YJR154W", "P27796", "YIL160C", "YDR142C", "P47181", "YJR154W", "P39108", "YDR142C", "P27796", "YIL160C" ] }, "reaction_10788486": { "compartment": "compartment_17947", "id": "reaction_10788486", "reactome": "R-SCE-9033527", "name": "PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788445", "species_10787658" ], "products": [ "species_10788447" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W" ] }, "reaction_10788441": { "compartment": "compartment_17947", "id": "reaction_10788441", "reactome": "R-SCE-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788427", "species_10788425" ], "products": [ "species_10788429" ], "modifiers": [], "additional_components": [ "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "Q05568", "YDR265W", "P15202", "YDR256C", "P32573", "YNL202W", "P32796", "YML042W", "P21954", "YDL066W", "P35056", "phospho-PEX5", "P13711", "YGL205W", "Q12524", "YLR151C", "Q02207", "YKR009C", "P16603", "YHR042W", "Q06010", "YLR389C", "P31787", "YGR037C", "P39994", "YEL020C", "P00175", "CYB2", "P41903", "YJR019C", "P15202", "YDR256C", "P32573", "YNL202W", "P53112", "PEX14", "P32796", "YML042W", "P21954", "YDL066W", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P13711", "YGL205W", "Q12524", "YLR151C", "Q02207", "YKR009C", "P80667", "PEX13", "P16603", "YHR042W", "Q04370", "YMR026C", "Q06010", "YLR389C", "P31787", "YGR037C", "P39994", "YEL020C", "P00175", "CYB2", "P41903", "YJR019C" ] }, "reaction_10788484": { "compartment": "compartment_17947", "id": "reaction_10788484", "reactome": "R-SCE-9033514", "name": "Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788476" ], "products": [ "species_10788445", "species_10788482" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P47181", "YJR154W", "P80667", "PEX13", "Q04370", "YMR026C", "P39108", "YDR142C", "P27796", "YIL160C", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P53112", "PEX14", "P80667", "PEX13", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W", "P47181", "YJR154W", "P27796", "YIL160C" ] }, "reaction_10788452": { "compartment": "compartment_17947", "id": "reaction_10788452", "reactome": "R-SCE-9033485", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788447" ], "products": [ "species_10772640", "species_10788449" ], "modifiers": [ [ "species_10788447", "catalyst" ] ], "additional_components": [ "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W", "P15731", "YBR082C", "P15732", "YDR059C", "P35056", "phospho-PEX5", "P53112", "PEX14", "P05759", "RPS31", "P80667", "PEX13", "Q04370", "YMR026C", "P39108", "YDR142C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05568", "YDR265W", "P35056", "phospho-PEX5", "P53112", "PEX14", "P15731", "YBR082C", "P15732", "YDR059C", "P05759", "RPS31", "P80667", "PEX13", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q04370", "YMR026C", "P39108", "YDR142C", "Q05568", "YDR265W" ] }, "reaction_10766513": { "compartment": "compartment_876", "id": "reaction_10766513", "reactome": "R-SCE-189242", "name": "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189246" ], "products": [ "species_189219" ], "modifiers": [ [ "species_10766510", "catalyst" ] ], "additional_components": [ "species_70113", "species_29532", "CHEBI:17118", "species_70113", "species_29532", "CHEBI:17118", "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10766502": { "compartment": "compartment_876", "id": "reaction_10766502", "reactome": "R-SCE-189222", "name": "SLC2A5 transports fructose from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189049" ], "products": [ "species_29532" ], "modifiers": [ [ "species_10766499", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10782658": { "compartment": "compartment_70101", "id": "reaction_10782658", "reactome": "R-SCE-6795290", "name": "TORC2 complex phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782648", "species_113592" ], "products": [ "species_29370", "species_10782656" ], "modifiers": [ [ "species_10767216", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "P11792", "YHR205W", "Q08236", "YOL078W", "P32600", "YKL203C", "P41318", "YNL006W", "P40061", "YER093C", "P38346", "YBR270C", "P47041", "YJL058C" ] }, "reaction_10782713": { "compartment": "compartment_7660", "id": "reaction_10782713", "reactome": "R-SCE-6797616", "name": "CCNK:CDK12 binds RNA Pol II at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782693", "species_10782677" ], "products": [ "species_10782695" ], "modifiers": [], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3", "Q03957", "YKL139W", "Q05949", "YLR226W", "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3" ] }, "reaction_10784265": { "compartment": "compartment_7660", "id": "reaction_10784265", "reactome": "R-SCE-6805640", "name": "AKT phosphorylates KAT6A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10775476" ], "products": [ "species_113582", "species_10784263" ], "modifiers": [ [ "species_10767347", "catalyst" ] ], "additional_components": [ "Q12311", "YPR031W", "Q08465", "YOR064C", "Q08649", "YOR244W", "P50947", "YNL097C", "P38806", "YHR090C", "P47128", "YJR082C", "Q12311", "YPR031W", "Q08649", "YOR244W", "Q08465", "YOR064C", "P50947", "YNL097C", "P38806", "YHR090C", "P47128", "YJR082C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10767160": { "compartment": "compartment_70101", "id": "reaction_10767160", "reactome": "R-SCE-198599", "name": "AKT phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10767147" ], "products": [ "species_29370", "species_10767157" ], "modifiers": [ [ "species_10767105", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10782671": { "compartment": "compartment_70101", "id": "reaction_10782671", "reactome": "R-SCE-6795473", "name": "PDPK1 phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10782656" ], "products": [ "species_29370", "species_10782666" ], "modifiers": [ [ "species_10764515", "catalyst" ] ], "additional_components": [ "P12688", "YKL126W", "P11792", "YHR205W", "P12688", "YKL126W", "P11792", "YHR205W", "species_179838", "Q12236", "YOL100W" ] }, "reaction_10784830": { "compartment": "compartment_7660", "id": "reaction_10784830", "reactome": "R-SCE-6810233", "name": "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784818", "species_29358" ], "products": [ "species_113582", "species_10784827" ], "modifiers": [ [ "species_10784818", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P53968", "YNL027W", "P04050", "YDL140C", "P32774", "YKL058W", "P13393", "SPT15", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P53968", "YNL027W", "P04050", "YDL140C", "P32774", "YKL058W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P53968", "YNL027W", "P04050", "YDL140C", "P32774", "YKL058W", "P13393", "SPT15", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C" ] }, "reaction_10784216": { "compartment": "compartment_7660", "id": "reaction_10784216", "reactome": "R-SCE-6804942", "name": "MDM2 homodimers auto-ubiquitinate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10760537", "species_10784206" ], "products": [ "species_10784213" ], "modifiers": [ [ "species_10784206", "catalyst" ] ], "additional_components": [ "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W" ] }, "reaction_10782642": { "compartment": "compartment_70101", "id": "reaction_10782642", "reactome": "R-SCE-6793666", "name": "MDM2 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767157" ], "products": [ "species_10768288" ], "modifiers": [], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W" ] }, "reaction_10782679": { "compartment": "compartment_7660", "id": "reaction_10782679", "reactome": "R-SCE-6797090", "name": "CCNK binds CDK12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782675", "species_10765011" ], "products": [ "species_10782677" ], "modifiers": [], "additional_components": [ "YKL139W", "YLR226W", "Q03957", "YKL139W", "Q05949", "YLR226W" ] }, "reaction_10784852": { "compartment": "compartment_7660", "id": "reaction_10784852", "reactome": "R-SCE-6810235", "name": "RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10784835", "species_10784846", "species_10784844", "species_10784827" ], "products": [ "species_10784850" ], "modifiers": [], "additional_components": [ "YER139C", "YDR289C", "Q05543", "YDR289C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q05027", "YMR236W", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P53968", "YNL027W", "P04050", "YDL140C", "P32774", "YKL058W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C", "P41896", "YGR005C", "Q04226", "YML015C", "P20434", "RPB5", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P53040", "YGL112C", "P29055", "YPR086W", "Q05027", "YMR236W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "P38129", "YBR198C", "Q05949", "YLR226W", "P36100", "YKL028W", "P22139", "RPB10", "P32773", "YOR194C", "P40084", "YER139C", "P53968", "YNL027W", "P04050", "YDL140C", "Q05543", "YDR289C", "P32774", "YKL058W", "P06242", "YDL108W", "P13393", "SPT15", "P20433", "YJL140W", "P16370", "YIL021W", "P41895", "YGR186W", "P40422", "RPC10", "P36145", "YKR062W", "P34087", "YDR404C", "P11747", "YML098W", "P46962", "YJL006C" ] }, "reaction_10765625": { "compartment": "compartment_5460", "id": "reaction_10765625", "reactome": "R-SCE-163310", "name": "TFAM binds to mitochondrial promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163305", "species_10765621" ], "products": [ "species_10765623" ], "modifiers": [], "additional_components": [ "Q03435", "YDL002C", "Q02486", "YMR072W", "P33417", "YKL032C", "Q03973", "YDR174W", "P11633", "YBR089C-A", "Q03435", "YDL002C", "Q02486", "YMR072W", "P33417", "YKL032C", "Q03973", "YDR174W", "P11633", "YBR089C-A" ] }, "reaction_10782685": { "compartment": "compartment_7660", "id": "reaction_10782685", "reactome": "R-SCE-6797100", "name": "CCNK binds CDK13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782681", "species_10765011" ], "products": [ "species_10782683" ], "modifiers": [], "additional_components": [ "YKL139W", "YLR226W", "Q03957", "YKL139W", "Q05949", "YLR226W" ] }, "reaction_10782673": { "compartment": "compartment_70101", "id": "reaction_10782673", "reactome": "R-SCE-6795667", "name": "MDM2 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10774893" ], "products": [ "species_10767147" ], "modifiers": [], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W" ] }, "reaction_10782640": { "compartment": "compartment_7660", "id": "reaction_10782640", "reactome": "R-SCE-6793661", "name": "(CDK1,CDK2):CCNA phosphorylates MDM2 at T218", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10768288" ], "products": [ "species_113582", "species_10782638" ], "modifiers": [ [ "species_10760454", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P00546", "YBR160W", "P30283", "YPR120C", "P20437", "YMR199W" ] }, "reaction_10782669": { "compartment": "compartment_70101", "id": "reaction_10782669", "reactome": "R-SCE-6795460", "name": "SGK1 phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10767147" ], "products": [ "species_29370", "species_10767157" ], "modifiers": [ [ "species_10782666", "catalyst" ] ], "additional_components": [ "Q05024", "YMR233W", "Q08747", "YOR295W", "Q05024", "YMR233W", "Q08747", "YOR295W", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10784258": { "compartment": "compartment_7660", "id": "reaction_10784258", "reactome": "R-SCE-6805061", "name": "CK2 binds FACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765099", "species_10784254" ], "products": [ "species_10784256" ], "modifiers": [], "additional_components": [ "P32558", "YGL207W", "Q04636", "YML069W", "P15790", "CKA1", "P38930", "CKB2", "P19454", "CKA2", "P15790", "CKA1", "P38930", "CKB2", "P32558", "YGL207W", "Q04636", "YML069W", "P19454", "CKA2" ] }, "reaction_10782711": { "compartment": "compartment_7660", "id": "reaction_10782711", "reactome": "R-SCE-6797606", "name": "CDK12 phosphorylates RNA Pol II CTD at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782695", "species_29358" ], "products": [ "species_113582", "species_10782708" ], "modifiers": [ [ "species_10782695", "catalyst" ] ], "additional_components": [ "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3", "P41896", "YGR005C", "P20434", "RPB5", "P32558", "YGL207W", "P20435", "RPO26", "Q03957", "YKL139W", "P38902", "YOL005C", "P32914", "YGR063C", "Q04673", "YLR005W", "P20436", "RPB8", "P08518", "YOR151C", "P27999", "YGL070C", "Q00578", "YIL143C", "Q12004", "YPR056W", "Q02939", "YPL122C", "Q05949", "YLR226W", "P07273", "YGL043W", "P22139", "RPB10", "P53861", "YNL230C", "P27692", "YML010W", "P04050", "YDL140C", "Q3E7C1", "YDR079C-A", "P37366", "YPR025C", "P32776", "YDR311W", "P06242", "YDL108W", "P20433", "YJL140W", "P16370", "YIL021W", "Q03290", "YDR460W", "Q03071", "YPL046C", "P36106", "YKL005C", "P41895", "YGR186W", "P40422", "RPC10", "Q04636", "YML069W", "Q03254", "YMR277W", "P34087", "YDR404C", "P46962", "YJL006C", "P06839", "RAD3" ] }, "reaction_10770856": { "compartment": "compartment_7660", "id": "reaction_10770856", "reactome": "R-SCE-450550", "name": "PKCalpha phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770833", "species_29358" ], "products": [ "species_113582", "species_10770851" ], "modifiers": [ [ "species_10770853", "catalyst" ] ], "additional_components": [ "YDR429C", "YDR429C", "YBL105C" ] }, "reaction_10770848": { "compartment": "compartment_7660", "id": "reaction_10770848", "reactome": "R-SCE-450533", "name": "PKCdelta phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770833", "species_29358" ], "products": [ "species_113582", "species_10770843" ], "modifiers": [ [ "species_10770845", "catalyst" ] ], "additional_components": [ "YDR429C", "YDR429C", "YBL105C" ] }, "reaction_10771129": { "compartment": "compartment_7660", "id": "reaction_10771129", "reactome": "R-SCE-517705", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770843", "species_517622" ], "products": [ "species_10771127" ], "modifiers": [], "additional_components": [ "YDR429C", "Q04067", "YDR429C" ] }, "reaction_10771125": { "compartment": "compartment_7660", "id": "reaction_10771125", "reactome": "R-SCE-517674", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450605", "species_10770851" ], "products": [ "species_10771123" ], "modifiers": [], "additional_components": [ "YDR429C", "Q04067", "YDR429C" ] }, "reaction_10770837": { "compartment": "compartment_7660", "id": "reaction_10770837", "reactome": "R-SCE-450494", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770833", "species_450613" ], "products": [ "species_10770835" ], "modifiers": [], "additional_components": [ "YDR429C", "Q04067", "YDR429C" ] }, "reaction_10776322": { "compartment": "compartment_7660", "id": "reaction_10776322", "reactome": "R-SCE-3878123", "name": "Initiation of SAHF formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776313", "species_10776308", "species_10776318", "species_10776303" ], "products": [ "species_10776320" ], "modifiers": [], "additional_components": [ "YBR215W", "YBL008W", "YJR140C", "YJL115W", "Q01448", "YBR215W", "P32479", "YBL008W", "P32447", "YJL115W", "P47171", "YJR140C" ] }, "reaction_10771087": { "compartment": "compartment_876", "id": "reaction_10771087", "reactome": "R-SCE-507868", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10771084", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771099": { "compartment": "compartment_876", "id": "reaction_10771099", "reactome": "R-SCE-507873", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29514" ], "products": [ "species_432019" ], "modifiers": [ [ "species_10771096", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10770170": { "compartment": "compartment_876", "id": "reaction_10770170", "reactome": "R-SCE-432074", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10770167", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771101": { "compartment": "compartment_876", "id": "reaction_10771101", "reactome": "R-SCE-507875", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10771096", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771094": { "compartment": "compartment_876", "id": "reaction_10771094", "reactome": "R-SCE-507871", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10771084", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10770159": { "compartment": "compartment_876", "id": "reaction_10770159", "reactome": "R-SCE-432049", "name": "Aquaporin-9 passively transports glycerol into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10770156", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771092": { "compartment": "compartment_876", "id": "reaction_10771092", "reactome": "R-SCE-507870", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10771084", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10771090": { "compartment": "compartment_876", "id": "reaction_10771090", "reactome": "R-SCE-507869", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10771084", "catalyst" ] ], "additional_components": [ "P23900", "YLL043W", "P43549", "YFL054C" ] }, "reaction_10772773": { "compartment": "compartment_876", "id": "reaction_10772773", "reactome": "R-SCE-1299338", "name": "Activation of TRESK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772770", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10772786": { "compartment": "compartment_876", "id": "reaction_10772786", "reactome": "R-SCE-1299359", "name": "Activation of TALK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772783", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10772753": { "compartment": "compartment_876", "id": "reaction_10772753", "reactome": "R-SCE-1299304", "name": "Activation of tandem pore domain in a weak inwardly rectifying K+ channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772750", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10772736": { "compartment": "compartment_876", "id": "reaction_10772736", "reactome": "R-SCE-1299297", "name": "Activation of THIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10772733", "catalyst" ] ], "additional_components": [ "P40310", "YJL093C" ] }, "reaction_10787432": { "compartment": "compartment_13231", "id": "reaction_10787432", "reactome": "R-SCE-8944457", "name": "MAF1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787425" ], "products": [ "species_10787423" ], "modifiers": [], "additional_components": [ "YDR005C", "YDR005C" ] }, "reaction_10764398": { "compartment": "compartment_7660", "id": "reaction_10764398", "reactome": "R-SCE-77589", "name": "Recognition of AAUAAA sequence by CPSF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762363", "species_10764394" ], "products": [ "species_10764396" ], "modifiers": [], "additional_components": [ "Q01329", "YAL043C", "Q12102", "YLR115W", "P45976", "YJR093C", "P42841", "YNL317W", "Q06224", "YLR277C", "Q06102", "YPR107C", "Q06632", "YDR301W", "P34160", "YMR125W", "Q08920", "YPL178W", "P34160", "YMR125W", "Q01329", "YAL043C", "Q12102", "YLR115W", "P45976", "YJR093C", "P42841", "YNL317W", "Q06224", "YLR277C", "Q08920", "YPL178W", "Q06102", "YPR107C", "Q06632", "YDR301W" ] }, "reaction_10789005": { "compartment": "compartment_70101", "id": "reaction_10789005", "reactome": "R-SCE-9664883", "name": "ATM:PEX5 translocates from cytosol to peroxisomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788984" ], "products": [ "species_10788990" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P38110", "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10788897": { "compartment": "compartment_70101", "id": "reaction_10788897", "reactome": "R-SCE-9646348", "name": "PolyUb-Misfolded Proteins:HDAC6 bind dynein motor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788876", "species_10788893" ], "products": [ "species_10788895" ], "modifiers": [], "additional_components": [ "P05759", "RPS31", "P53973", "YNL021W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P0CE68", "YKR103W", "P12866", "YKL209C", "Q02647", "YDR424C", "P40960", "YDR488C", "P36022", "YKR054C", "P05759", "RPS31", "Q02647", "YDR424C", "P53973", "YNL021W", "P40960", "YDR488C", "P36022", "YKR054C", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10788915": { "compartment": "compartment_18667", "id": "reaction_10788915", "reactome": "R-SCE-9646685", "name": "Aggresome dissociates from dynein and microtubule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788907" ], "products": [ "species_10768744", "species_10788913", "species_10788893" ], "modifiers": [], "additional_components": [ "P02557", "YFL037W", "P40960", "YDR488C", "P36022", "YKR054C", "species_29438", "P0CE68", "YKR103W", "species_29420", "P09734", "YML124C", "P05759", "RPS31", "P09733", "YML085C", "Q02647", "YDR424C", "P53973", "YNL021W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P12866", "YKL209C", "species_29420", "P09734", "YML124C", "P09733", "YML085C", "P02557", "YFL037W", "species_29438", "P05759", "RPS31", "P53973", "YNL021W", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P0CE68", "YKR103W", "P12866", "YKL209C", "Q02647", "YDR424C", "P40960", "YDR488C", "P36022", "YKR054C" ] }, "reaction_10789014": { "compartment": "compartment_17947", "id": "reaction_10789014", "reactome": "R-SCE-9664888", "name": "ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788999" ], "products": [ "species_10789012" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P38110", "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10788869": { "compartment": "compartment_70101", "id": "reaction_10788869", "reactome": "R-SCE-9641127", "name": "Ub:misfolded proteins polymerize to PolyUb:misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788867" ], "products": [ "species_10788867" ], "modifiers": [], "additional_components": [ "P05759", "RPS31", "P53152", "MMS2", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52490", "UBC13", "P0CE68", "YKR103W", "P12866", "YKL209C", "P05759", "RPS31", "P53152", "MMS2", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P52490", "UBC13", "P0CE68", "YKR103W", "P12866", "YKL209C" ] }, "reaction_10789001": { "compartment": "compartment_17947", "id": "reaction_10789001", "reactome": "R-SCE-9664862", "name": "ATM dimer:PEX5 phosphorylates PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788992" ], "products": [ "species_10788999" ], "modifiers": [], "additional_components": [ "P35056", "phospho-PEX5", "P38110", "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10788986": { "compartment": "compartment_70101", "id": "reaction_10788986", "reactome": "R-SCE-9664850", "name": "ATM binds PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788982", "species_10788423" ], "products": [ "species_10788984" ], "modifiers": [], "additional_components": [ "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10789003": { "compartment": "compartment_17947", "id": "reaction_10789003", "reactome": "R-SCE-9664879", "name": "ATM:PEX5 binds ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788990", "species_10788988" ], "products": [ "species_10788992" ], "modifiers": [ [ "species_1250243", "catalyst" ] ], "additional_components": [ "P35056", "phospho-PEX5", "P38110", "YBL088C", "YBL088C", "P35056", "phospho-PEX5", "P38110", "YBL088C" ] }, "reaction_10763693": { "compartment": "compartment_17940", "id": "reaction_10763693", "reactome": "R-SCE-74723", "name": "Endosome acidification", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_74722" ], "modifiers": [ [ "species_10763690", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "P23968", "YHR026W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10779165": { "compartment": "compartment_7660", "id": "reaction_10779165", "reactome": "R-SCE-5682026", "name": "MRN bound to shortened telomeres activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779160" ], "products": [ "species_113582", "species_10779162", "species_10768327" ], "modifiers": [ [ "species_10779160", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10787738": { "compartment": "compartment_7660", "id": "reaction_10787738", "reactome": "R-SCE-8979071", "name": "KDM6B binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111793", "species_10775179" ], "products": [ "species_10775181" ], "modifiers": [], "additional_components": [ "YBR112C", "P14922", "YBR112C", "species_111793" ] }, "reaction_10775231": { "compartment": "compartment_7660", "id": "reaction_10775231", "reactome": "R-SCE-3239019", "name": "Active p38 MAPK phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10775221" ], "products": [ "species_113582", "species_10775228" ], "modifiers": [ [ "species_10775221", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W" ] }, "reaction_10775223": { "compartment": "compartment_7660", "id": "reaction_10775223", "reactome": "R-SCE-3238999", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10775219" ], "products": [ "species_113582", "species_10775221" ], "modifiers": [ [ "species_10770705", "catalyst" ] ], "additional_components": [ "P32485", "YLR113W", "P36003", "YKL171W", "P32485", "YLR113W", "P36003", "YKL171W", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C" ] }, "reaction_10782617": { "compartment": "compartment_7660", "id": "reaction_10782617", "reactome": "R-SCE-6792712", "name": "KAT5 acetylates ATM at shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10782614", "species_113560" ], "products": [ "species_2485002", "species_10779160" ], "modifiers": [ [ "species_10782614", "catalyst" ] ], "additional_components": [ "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C", "P12753", "DNA repair protein RAD50", "P32829", "MRE11", "P34218", "YBL052C", "P38110", "YBL088C" ] }, "reaction_10775192": { "compartment": "compartment_70101", "id": "reaction_10775192", "reactome": "R-SCE-3228469", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770760", "species_113592" ], "products": [ "species_29370", "species_10770683" ], "modifiers": [ [ "species_10775189", "catalyst" ] ], "additional_components": [ "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C", "P32490", "YOR231W", "P06784", "YDL159W", "P32491", "YPL140C", "P08018", "YJL128C", "YLR362W" ] }, "reaction_10775184": { "compartment": "compartment_7660", "id": "reaction_10775184", "reactome": "R-SCE-3222593", "name": "KDM6B demethylates H3K27me3 on p16INK4A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775172", "species_113671" ], "products": [ "species_10775174", "species_159939" ], "modifiers": [ [ "species_10775181", "catalyst" ] ], "additional_components": [ "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P02294", "YBL002W", "P02309", "YBR009C", "P36012", "YKL049C", "P02293", "YDR224C", "Q12692", "YOL012C", "P04912", "YBL003C", "P04911", "YDR225W", "P61830", "YBR010W", "P14922", "YBR112C", "species_111793" ] }, "reaction_10771963": { "compartment": "compartment_70101", "id": "reaction_10771963", "reactome": "R-SCE-947591", "name": "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_947588", "species_29356" ], "products": [ "species_29370", "species_947594", "species_29372" ], "modifiers": [ [ "species_10771935", "catalyst" ] ], "additional_components": [ "species_33625", "species_1500581", "species_33625", "species_1500581", "P32660", "YER166W", "P39524", "YAL026C", "P40527", "YIL048W", "Q12675", "YDR093W", "Q12674", "YMR162C" ] }, "reaction_10777455": { "compartment": "compartment_70101", "id": "reaction_10777455", "reactome": "R-SCE-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_5252122" ], "products": [ "species_29370", "species_5252016", "species_29372" ], "modifiers": [ [ "species_10777450", "catalyst" ] ], "additional_components": [ "YOR291W" ] }, "reaction_10775325": { "compartment": "compartment_70101", "id": "reaction_10775325", "reactome": "R-SCE-3295579", "name": "TRPs transport extracellular Ca2+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10775312", "catalyst" ] ], "additional_components": [ "YOR087W" ] }, "reaction_10781096": { "compartment": "compartment_70101", "id": "reaction_10781096", "reactome": "R-SCE-5692462", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29418", "species_29356" ], "products": [ "species_29370", "species_29372", "species_1981162" ], "modifiers": [ [ "species_10781093", "catalyst" ] ], "additional_components": [ "YEL031W" ] }, "reaction_10771860": { "compartment": "compartment_20699", "id": "reaction_10771860", "reactome": "R-SCE-936883", "name": "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_113592", "species_29356" ], "products": [ "species_29370", "species_167012", "species_29372" ], "modifiers": [ [ "species_10771857", "catalyst" ] ], "additional_components": [ "species_109496", "P13586", "YGL167C" ] }, "reaction_10771868": { "compartment": "compartment_20699", "id": "reaction_10771868", "reactome": "R-SCE-936895", "name": "ATP7B transports cytosolic Cu2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_209799" ], "products": [ "species_29370", "species_936901", "species_29372" ], "modifiers": [ [ "species_10771865", "catalyst" ] ], "additional_components": [ "YDR270W" ] }, "reaction_10781101": { "compartment": "compartment_70101", "id": "reaction_10781101", "reactome": "R-SCE-5692480", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_5692450" ], "products": [ "species_29370", "species_29372", "species_5692484" ], "modifiers": [ [ "species_10781098", "catalyst" ] ], "additional_components": [ "YOR291W" ] }, "reaction_10774664": { "compartment": "compartment_70101", "id": "reaction_10774664", "reactome": "R-SCE-2684901", "name": "ANOs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10774659", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "YBR086C" ] }, "reaction_10789201": { "compartment": "compartment_70101", "id": "reaction_10789201", "reactome": "R-SCE-9701141", "name": "TRPV1 transports Ca2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10775312", "catalyst" ] ], "additional_components": [ "YOR087W" ] }, "reaction_10774674": { "compartment": "compartment_70101", "id": "reaction_10774674", "reactome": "R-SCE-2730692", "name": "CLCN4/5/6 exchange Cl- for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_2731008" ], "products": [ "species_352022", "species_74722" ], "modifiers": [ [ "species_10774669", "catalyst" ] ], "additional_components": [ "YJR040W" ] }, "reaction_10768792": { "compartment": "compartment_12045", "id": "reaction_10768792", "reactome": "R-SCE-381091", "name": "IRE1 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768784", "species_113592" ], "products": [ "species_29370", "species_10768789" ], "modifiers": [ [ "species_10768784", "catalyst" ] ], "additional_components": [ "P32361", "phospho-IRE1", "P32361", "phospho-IRE1", "P32361", "phospho-IRE1" ] }, "reaction_10768794": { "compartment": "compartment_12045", "id": "reaction_10768794", "reactome": "R-SCE-381109", "name": "IRE1 binds IRE1 forming dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768782" ], "products": [ "species_10768784" ], "modifiers": [], "additional_components": [ "P32361", "phospho-IRE1" ] }, "reaction_10770262": { "compartment": "compartment_12045", "id": "reaction_10770262", "reactome": "R-SCE-442393", "name": "ZIP7 mediates zinc efflux from the endoplasmic reticulum", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_442320" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10770259", "catalyst" ] ], "additional_components": [ "YIL023C" ] }, "reaction_10779105": { "compartment": "compartment_70101", "id": "reaction_10779105", "reactome": "R-SCE-5679206", "name": "MTMR14, MTMR3 dephosphorylate PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030" ], "products": [ "species_426639" ], "modifiers": [ [ "species_10773546", "catalyst" ] ], "additional_components": [ "YJR110W" ] }, "reaction_10778999": { "compartment": "compartment_70101", "id": "reaction_10778999", "reactome": "R-SCE-5675868", "name": "ULK1 phosphorylates ATG13 and RB1CC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778709", "species_113592" ], "products": [ "species_29370", "species_10778996" ], "modifiers": [ [ "species_10778709", "catalyst" ] ], "additional_components": [ "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779119": { "compartment": "compartment_70101", "id": "reaction_10779119", "reactome": "R-SCE-5681980", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779063", "species_10779115" ], "products": [ "species_10779117" ], "modifiers": [], "additional_components": [ "YBR217W", "P38862", "YHR171W", "P38316", "YBR217W", "P38862", "YHR171W" ] }, "reaction_10778714": { "compartment": "compartment_70101", "id": "reaction_10778714", "reactome": "R-SCE-5672011", "name": "p-AMPK:AMP binds the ULK complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778630", "species_10768748" ], "products": [ "species_10778632" ], "modifiers": [], "additional_components": [ "P53104", "YGL180W", "Q06628", "YPR185W", "Q12527", "YPR049C", "P36002", "YKL198C", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "P36002", "YKL198C", "P34164", "YGL208W", "P53104", "YGL180W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "Q06628", "YPR185W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10788354": { "compartment": "compartment_70101", "id": "reaction_10788354", "reactome": "R-SCE-9020616", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779117" ], "products": [ "species_10779327" ], "modifiers": [], "additional_components": [ "P38316", "YBR217W", "P38862", "YHR171W", "P38316", "YBR217W", "P38862", "YHR171W" ] }, "reaction_10779133": { "compartment": "compartment_70101", "id": "reaction_10779133", "reactome": "R-SCE-5681981", "name": "ATG3 transfers LC3 from ATG7 to ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779128" ], "products": [ "species_10779130" ], "modifiers": [ [ "species_10779128", "catalyst" ] ], "additional_components": [ "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C", "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C", "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C" ] }, "reaction_10778727": { "compartment": "compartment_12045", "id": "reaction_10778727", "reactome": "R-SCE-5672012", "name": "Beclin-1 complex phosphorylates PtdIns", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_5676030", "species_29370" ], "modifiers": [ [ "species_10778724", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W" ] }, "reaction_10778646": { "compartment": "compartment_70101", "id": "reaction_10778646", "reactome": "R-SCE-5665868", "name": "AMPK (complex) phosphorylates ULK1 (complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778632", "species_113592" ], "products": [ "species_29370", "species_10778643" ], "modifiers": [ [ "species_10778632", "catalyst" ] ], "additional_components": [ "P36002", "YKL198C", "P34164", "YGL208W", "P53104", "YGL180W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "Q06628", "YPR185W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P34164", "YGL208W", "P53104", "YGL180W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "Q06628", "YPR185W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779026": { "compartment": "compartment_70101", "id": "reaction_10779026", "reactome": "R-SCE-5676229", "name": "WIPIs bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779022", "species_5693050" ], "products": [ "species_10779024" ], "modifiers": [], "additional_components": [ "Q02887", "YPL100W", "P43601", "YFR021W", "P50079", "YGR223C", "Q02887", "YPL100W", "P43601", "YFR021W", "species_1629751", "P50079", "YGR223C" ] }, "reaction_10778712": { "compartment": "compartment_70101", "id": "reaction_10778712", "reactome": "R-SCE-5672008", "name": "Thr-180 of ULK1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778643", "species_113592" ], "products": [ "species_29370", "species_10778709" ], "modifiers": [ [ "species_10778643", "catalyst" ] ], "additional_components": [ "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779077": { "compartment": "compartment_70101", "id": "reaction_10779077", "reactome": "R-SCE-5678490", "name": "ATG16L1 complex transfers LC3 from ATG3 to PE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5681998", "species_10779055" ], "products": [ "species_10779059", "species_10779057" ], "modifiers": [ [ "species_10779074", "catalyst" ] ], "additional_components": [ "P40344", "YNR007C", "P38182", "YBL078C", "YNR007C", "species_1500581", "P38182", "YBL078C", "species_6809774", "Q12380", "YPL149W", "P43601", "YFR021W", "P38316", "YBR217W" ] }, "reaction_10779143": { "compartment": "compartment_70101", "id": "reaction_10779143", "reactome": "R-SCE-5682011", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779041", "species_10779115" ], "products": [ "species_10779126" ], "modifiers": [], "additional_components": [ "YBL078C", "P38862", "YHR171W", "P38862", "YHR171W", "P38182", "YBL078C" ] }, "reaction_10779211": { "compartment": "compartment_5683628", "id": "reaction_10779211", "reactome": "R-SCE-5682388", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779057" ], "products": [ "species_10779202" ], "modifiers": [ [ "species_10779209", "catalyst" ], [ "species_10771366", "catalyst" ] ], "additional_components": [ "species_1500581", "P38182", "YBL078C", "species_1500581", "P38182", "YBL078C", "Q05919", "YLR360W", "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "Q04272", "YMR077C" ] }, "reaction_10779191": { "compartment": "compartment_12045", "id": "reaction_10779191", "reactome": "R-SCE-5682385", "name": "The phagophore extends from the PIP3-enriched structure", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778724" ], "products": [ "species_10779182" ], "modifiers": [ [ "species_10779187", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "YDL149W" ] }, "reaction_10779329": { "compartment": "compartment_70101", "id": "reaction_10779329", "reactome": "R-SCE-5682896", "name": "LC3:ATG7 dimer binds ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779059", "species_10779126" ], "products": [ "species_10779128" ], "modifiers": [], "additional_components": [ "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C", "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C" ] }, "reaction_10779107": { "compartment": "compartment_70101", "id": "reaction_10779107", "reactome": "R-SCE-5679239", "name": "ULK complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778996" ], "products": [ "species_10779099" ], "modifiers": [], "additional_components": [ "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779420": { "compartment": "compartment_70101", "id": "reaction_10779420", "reactome": "R-SCE-5683925", "name": "ULK1 is dephosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779418" ], "products": [ "species_10778630", "species_29372" ], "modifiers": [], "additional_components": [ "P53104", "YGL180W", "Q06628", "YPR185W", "Q12527", "YPR049C", "P53104", "YGL180W", "Q06628", "YPR185W", "Q12527", "YPR049C" ] }, "reaction_10779102": { "compartment": "compartment_70101", "id": "reaction_10779102", "reactome": "R-SCE-5679205", "name": "ULK1 phosphorylates Beclin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779087", "species_113592" ], "products": [ "species_29370", "species_10778724" ], "modifiers": [ [ "species_10779099", "catalyst" ] ], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P36002", "YKL198C", "P53104", "YGL180W", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "Q06628", "YPR185W", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "Q12527", "YPR049C" ] }, "reaction_10779387": { "compartment": "compartment_70101", "id": "reaction_10779387", "reactome": "R-SCE-5683593", "name": "ATG7:ATG3:LC3 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779130" ], "products": [ "species_10779115", "species_10779055" ], "modifiers": [], "additional_components": [ "P40344", "YNR007C", "P38862", "YHR171W", "P38182", "YBL078C", "P38862", "YHR171W", "P40344", "YNR007C", "P38182", "YBL078C" ] }, "reaction_10779113": { "compartment": "compartment_70101", "id": "reaction_10779113", "reactome": "R-SCE-5679266", "name": "Beclin-1 complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779111" ], "products": [ "species_10779087" ], "modifiers": [], "additional_components": [ "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W", "P22543", "YLR240W", "P22219", "YBR097W", "Q02948", "YPL120W" ] }, "reaction_10769778": { "compartment": "compartment_17938", "id": "reaction_10769778", "reactome": "R-SCE-428007", "name": "Proton-coupled histidine and di-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427984", "species_428040" ], "products": [ "species_70106", "species_428003" ], "modifiers": [ [ "species_10769773", "catalyst" ] ], "additional_components": [ "CHEBI:90799", "CHEBI:32513", "CHEBI:32513", "CHEBI:46761", "YKR093W" ] }, "reaction_10787736": { "compartment": "compartment_70101", "id": "reaction_10787736", "reactome": "R-SCE-8959798", "name": "SLC30A10 transports Mn2+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29418" ], "products": [ "species_266099" ], "modifiers": [ [ "species_10787733", "catalyst" ] ], "additional_components": [ "P20107", "YMR243C", "P32798", "YOR316C" ] }, "reaction_10770232": { "compartment": "compartment_876", "id": "reaction_10770232", "reactome": "R-SCE-437300", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_437295" ], "products": [ "species_209799" ], "modifiers": [ [ "species_10770229", "catalyst" ] ], "additional_components": [ "YHR175W" ] }, "reaction_10770216": { "compartment": "compartment_876", "id": "reaction_10770216", "reactome": "R-SCE-435366", "name": "ZnT1 mediates the efflux of zinc from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_158417" ], "modifiers": [ [ "species_10770213", "catalyst" ] ], "additional_components": [ "YMR243C" ] }, "reaction_10770208": { "compartment": "compartment_876", "id": "reaction_10770208", "reactome": "R-SCE-434650", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_446589", "species_351626" ], "products": [ "species_70106", "species_446597" ], "modifiers": [ [ "species_10770205", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:16737", "LigandDisplayForward?ligandId=1231", "CHEBI:641", "CHEBI:6801", "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:16737", "LigandDisplayForward?ligandId=1231", "CHEBI:641", "CHEBI:6801", "P38767", "YHR032W", "Q05497", "YDR338C" ] }, "reaction_10769984": { "compartment": "compartment_876", "id": "reaction_10769984", "reactome": "R-SCE-429101", "name": "HMIT co-transports myo-inositol with a proton", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429130", "species_351626" ], "products": [ "species_70106", "species_426910" ], "modifiers": [ [ "species_10769981", "catalyst" ] ], "additional_components": [ "YDR497C" ] }, "reaction_10769870": { "compartment": "compartment_201753", "id": "reaction_10769870", "reactome": "R-SCE-428625", "name": "Vesicular inhibitory amino acid transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428548", "species_428592" ], "products": [ "species_70106", "species_428632" ], "modifiers": [ [ "species_10769867", "catalyst" ] ], "additional_components": [ "species_916850", "species_29424", "species_916850", "species_29424", "YJR001W" ] }, "reaction_10785998": { "compartment": "compartment_70101", "id": "reaction_10785998", "reactome": "R-SCE-8855062", "name": "SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162252", "species_71284" ], "products": [ "species_71285", "species_2162265" ], "modifiers": [ [ "species_10785995", "catalyst" ] ], "additional_components": [ "YNL003C" ] }, "reaction_10768477": { "compartment": "compartment_876", "id": "reaction_10768477", "reactome": "R-SCE-352158", "name": "SLC16A10-mediated uptake of aromatic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352161" ], "products": [ "species_352139" ], "modifiers": [ [ "species_10768474", "catalyst" ] ], "additional_components": [ "species_29502", "species_29500", "CHEBI:58315", "species_29502", "species_29500", "CHEBI:58315", "P25568", "YCL038C", "P53918", "YNL125C", "Q08777", "YOR306C", "Q08268", "YOL119C", "P36032", "YKL221W" ] }, "reaction_10778165": { "compartment": "compartment_70101", "id": "reaction_10778165", "reactome": "R-SCE-5627802", "name": "SLC26A4 transports I- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209785" ], "products": [ "species_209818" ], "modifiers": [ [ "species_10778162", "catalyst" ] ], "additional_components": [ "YPR003C" ] }, "reaction_10768673": { "compartment": "compartment_876", "id": "reaction_10768673", "reactome": "R-SCE-379432", "name": "SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29588", "species_379430" ], "products": [ "species_351964", "species_379440" ], "modifiers": [ [ "species_10768670", "catalyst" ] ], "additional_components": [ "species_379444", "species_1131871", "species_29468", "species_379444", "species_1131871", "species_29468", "P53341", "YGR292W", "P53051", "YGR287C", "P50276", "YGR055W", "P38734", "YHL036W", "P38158", "YBR299W", "P40884", "YJL216C", "P0CW41", "YJL221C", "P0CW40", "YIL172C", "Q08295", "YOL157C" ] }, "reaction_10769768": { "compartment": "compartment_876", "id": "reaction_10769768", "reactome": "R-SCE-427666", "name": "SLC26A3,6 exchange Cl- for HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111627", "species_188972" ], "products": [ "species_352022", "species_425425" ], "modifiers": [ [ "species_10769765", "catalyst" ] ], "additional_components": [ "P53394", "YPR003C" ] }, "reaction_10777542": { "compartment": "compartment_70101", "id": "reaction_10777542", "reactome": "R-SCE-5340130", "name": "CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5673778", "species_428040" ], "products": [ "species_70106", "species_379444" ], "modifiers": [ [ "species_10777539", "catalyst" ] ], "additional_components": [ "YCR075C" ] }, "reaction_10769759": { "compartment": "compartment_876", "id": "reaction_10769759", "reactome": "R-SCE-427570", "name": "Group 3 - Selective Cl- transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10769756", "catalyst" ] ], "additional_components": [ "P53394", "YPR003C" ] }, "reaction_10786838": { "compartment": "compartment_70101", "id": "reaction_10786838", "reactome": "R-SCE-8875871", "name": "SLC26A11 transports SO4(2-) from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648" ], "products": [ "species_174375" ], "modifiers": [ [ "species_10786835", "catalyst" ] ], "additional_components": [ "YBR294W" ] }, "reaction_10767238": { "compartment": "compartment_7660", "id": "reaction_10767238", "reactome": "R-SCE-198714", "name": "ERK5 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767234" ], "products": [ "species_10767236" ], "modifiers": [], "additional_components": [ "YPR054W", "YPR054W" ] }, "reaction_10778793": { "compartment": "compartment_70101", "id": "reaction_10778793", "reactome": "R-SCE-5674496", "name": "Activated MAPKs phosphorylate MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10778763" ], "products": [ "species_29370", "species_10778790" ], "modifiers": [ [ "species_10778780", "catalyst" ] ], "additional_components": [ "P06784", "YDL159W", "P06784", "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10779550": { "compartment": "compartment_7660", "id": "reaction_10779550", "reactome": "R-SCE-5687091", "name": "p-S MAPK6,4 binds MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775217", "species_10779544" ], "products": [ "species_10779548" ], "modifiers": [], "additional_components": [ "YKL171W", "YPR054W", "P41808", "YPR054W", "P36003", "YKL171W" ] }, "reaction_10780903": { "compartment": "compartment_70101", "id": "reaction_10780903", "reactome": "R-SCE-5690250", "name": "p-T182-MAPKAPK5 phoshphorylates DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10780891" ], "products": [ "species_29370", "species_10780900" ], "modifiers": [ [ "species_10780891", "catalyst" ] ], "additional_components": [ "P25294", "YNL007C", "P36003", "YKL171W", "P25294", "YNL007C", "P36003", "YKL171W", "P25294", "YNL007C", "P36003", "YKL171W" ] }, "reaction_10779572": { "compartment": "compartment_7660", "id": "reaction_10779572", "reactome": "R-SCE-5687109", "name": "MAPK4,6 translocate to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779563" ], "products": [ "species_10779557" ], "modifiers": [ [ "species_10779570", "catalyst" ] ], "additional_components": [ "P41808", "YPR054W", "P41808", "YPR054W", "YGR218W" ] }, "reaction_10779583": { "compartment": "compartment_7660", "id": "reaction_10779583", "reactome": "R-SCE-5687123", "name": "p-S115 MAPKAPK5 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779529" ], "products": [ "species_10779581" ], "modifiers": [], "additional_components": [ "YKL171W", "YKL171W" ] }, "reaction_10779542": { "compartment": "compartment_7660", "id": "reaction_10779542", "reactome": "R-SCE-5687088", "name": "PKA phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775217", "species_29358" ], "products": [ "species_113582", "species_10779529" ], "modifiers": [ [ "species_10779539", "catalyst" ] ], "additional_components": [ "YKL171W", "YKL171W", "P05986", "YKL166C", "P06245", "YPL203W", "P06244", "YJL164C" ] }, "reaction_10781177": { "compartment": "compartment_70101", "id": "reaction_10781177", "reactome": "R-SCE-5692770", "name": "SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781173", "species_10779577", "species_10779523" ], "products": [ "species_10781175" ], "modifiers": [], "additional_components": [ "P32457", "YLR314C", "Q07657", "YDL225W", "Q04921", "YDR218C", "P32468", "YHR107C", "P41901", "YGR059W", "P32458", "YJR076C", "YKL171W", "YPR054W", "P41808", "YPR054W", "P32457", "YLR314C", "Q07657", "YDL225W", "Q04921", "YDR218C", "P32468", "YHR107C", "P36003", "YKL171W", "P41901", "YGR059W", "P32458", "YJR076C" ] }, "reaction_10779565": { "compartment": "compartment_70101", "id": "reaction_10779565", "reactome": "R-SCE-5687107", "name": "MAPK4,6 translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779557" ], "products": [ "species_10779563" ], "modifiers": [], "additional_components": [ "P41808", "YPR054W", "P41808", "YPR054W" ] }, "reaction_10780893": { "compartment": "compartment_70101", "id": "reaction_10780893", "reactome": "R-SCE-5690245", "name": "p-T182 MAPKAPK5 binds DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779577", "species_10775708" ], "products": [ "species_10780891" ], "modifiers": [], "additional_components": [ "YKL171W", "YNL007C", "P25294", "YNL007C", "P36003", "YKL171W" ] }, "reaction_10779526": { "compartment": "compartment_70101", "id": "reaction_10779526", "reactome": "R-SCE-5687086", "name": "PAK1,2,3 phosphorylates MAPK6,4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779517", "species_113592" ], "products": [ "species_29370", "species_10779520" ], "modifiers": [ [ "species_10778157", "catalyst" ] ], "additional_components": [ "YPR054W", "YPR054W", "P48562", "YNL298W", "Q03497", "YHL007C", "Q12469", "YOL113W" ] }, "reaction_10779575": { "compartment": "compartment_70101", "id": "reaction_10779575", "reactome": "R-SCE-5687112", "name": "MAPK6 is degraded by the 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779515" ], "products": [ "species_10760634" ], "modifiers": [ [ "species_10760825", "catalyst" ] ], "additional_components": [ "YPR054W", "P05759", "RPS31", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P40327", "YDL007W", "P25043", "YOR157C", "Q12250", "YDL147W", "P30656", "YPR103W", "P38764", "YHR027C", "P32565", "YIL075C", "P22141", "YER012W", "Q08723", "YOR261C", "P40303", "YOL038W", "P38624", "YJL001W", "P21242", "YOR362C", "Q01939", "YGL048C", "P32496", "YFR052W", "P38886", "YHR200W", "P23639", "YML092C", "P30657", "YFR050C", "P32379", "YGR253C", "P40555", "YIL007C", "P21243", "YGL011C", "P40302", "YMR314W", "Q06103", "YPR108W", "P53549", "YOR259C", "P23724", "YBL041W", "P43583", "YFL007W", "Q04062", "YDR427W", "P33299", "YKL145W", "P33297", "YOR117W", "P40016", "YER021W", "Q12377", "YDL097C", "P25451", "YER094C", "P23638", "YGR135W", "P43588", "YFR004W", "P33298", "YDR394W" ] }, "reaction_10781115": { "compartment": "compartment_7660", "id": "reaction_10781115", "reactome": "R-SCE-5692749", "name": "CDC14A,B bind MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781107", "species_10781109" ], "products": [ "species_10781113" ], "modifiers": [], "additional_components": [ "YPR054W", "YFR028C", "P41808", "YPR054W", "Q00684", "YFR028C" ] }, "reaction_10781120": { "compartment": "compartment_7660", "id": "reaction_10781120", "reactome": "R-SCE-5692754", "name": "CDC14A,B dephosphorylate p-3S,T MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10781113" ], "products": [ "species_113550", "species_10781117" ], "modifiers": [ [ "species_10781113", "catalyst" ] ], "additional_components": [ "P41808", "YPR054W", "Q00684", "YFR028C", "P41808", "YPR054W", "Q00684", "YFR028C", "P41808", "YPR054W", "Q00684", "YFR028C" ] }, "reaction_10779555": { "compartment": "compartment_7660", "id": "reaction_10779555", "reactome": "R-SCE-5687094", "name": "p-S MAPK6,4 phosphorylate MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10779548" ], "products": [ "species_113582", "species_10779552" ], "modifiers": [ [ "species_10779548", "catalyst" ] ], "additional_components": [ "P41808", "YPR054W", "P36003", "YKL171W", "P41808", "YPR054W", "P36003", "YKL171W", "P41808", "YPR054W", "P36003", "YKL171W" ] }, "reaction_10779579": { "compartment": "compartment_7660", "id": "reaction_10779579", "reactome": "R-SCE-5687120", "name": "p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10779552" ], "products": [ "species_10779577", "species_10779520" ], "modifiers": [], "additional_components": [ "P41808", "YPR054W", "P36003", "YKL171W", "YKL171W", "YPR054W" ] }, "reaction_10781140": { "compartment": "compartment_7660", "id": "reaction_10781140", "reactome": "R-SCE-5692764", "name": "MAPK6 binds CCND3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781136", "species_10779561" ], "products": [ "species_10781138" ], "modifiers": [ [ "species_10781109", "catalyst" ] ], "additional_components": [ "P13365", "YAL040C", "P20438", "YPL256C", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "YPR054W", "P13365", "YAL040C", "P20438", "YPL256C", "P41808", "YPR054W", "P32943", "YGR109C", "P24868", "YGR108W", "P24869", "YPR119W", "P30283", "YPR120C", "P20437", "YMR199W", "YFR028C" ] }, "reaction_10770806": { "compartment": "compartment_70101", "id": "reaction_10770806", "reactome": "R-SCE-450463", "name": "MK2 phosphorylates ZFP36 (Tristetraproline, TTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770793", "species_113592" ], "products": [ "species_29370", "species_10770785" ], "modifiers": [ [ "species_10766447", "catalyst" ] ], "additional_components": [ "P47976", "YDR151C", "P38217", "YBR017C", "P47977", "YLR136C", "P47976", "YDR151C", "P38217", "YBR017C", "P47977", "YLR136C", "YKL171W" ] }, "reaction_10770831": { "compartment": "compartment_70101", "id": "reaction_10770831", "reactome": "R-SCE-450490", "name": "Protein Kinase B/Akt phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770810", "species_113592" ], "products": [ "species_29370", "species_10770828" ], "modifiers": [ [ "species_10767095", "catalyst" ] ], "additional_components": [ "P47976", "YDR151C", "P47976", "YDR151C", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10770803": { "compartment": "compartment_70101", "id": "reaction_10770803", "reactome": "R-SCE-450431", "name": "ZFP36 (TTP) recruits RNA degradation activities", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770123", "species_10770057", "species_10770793", "species_10770799", "species_10770050" ], "products": [ "species_10770801" ], "modifiers": [], "additional_components": [ "P53859", "CSL4", "Q08285", "RRP40", "P53256", "RRP46", "P38792", "RRP4", "Q12277", "RRP42", "P48240", "MTR3", "Q08162", "DIS3", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "YNL118C", "P47976", "YDR151C", "P38217", "YBR017C", "P47977", "YLR136C", "YOL149W", "P47976", "YDR151C", "P53859", "CSL4", "Q08285", "RRP40", "P22147", "XRN1", "Q12277", "RRP42", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "P53550", "YNL118C", "P38217", "YBR017C", "P53256", "RRP46", "P38792", "RRP4", "P48240", "MTR3", "Q12517", "YOL149W", "Q08162", "DIS3", "P47977", "YLR136C" ] }, "reaction_10770824": { "compartment": "compartment_70101", "id": "reaction_10770824", "reactome": "R-SCE-450488", "name": "BRF1 Complex recruits RNA degradation activities", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770123", "species_10770810", "species_10770057", "species_10770799", "species_10770050" ], "products": [ "species_10770822" ], "modifiers": [], "additional_components": [ "P53859", "CSL4", "Q08285", "RRP40", "P53256", "RRP46", "P38792", "RRP4", "Q12277", "RRP42", "P48240", "MTR3", "Q08162", "DIS3", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "P47976", "YDR151C", "YNL118C", "YOL149W", "P47976", "YDR151C", "P53859", "CSL4", "Q08285", "RRP40", "P22147", "XRN1", "Q12277", "RRP42", "P46948", "SKI6", "Q05636", "RRP45", "P25359", "RRP43", "P53550", "YNL118C", "P53256", "RRP46", "P38792", "RRP4", "P48240", "MTR3", "Q12517", "YOL149W", "Q08162", "DIS3" ] }, "reaction_10770795": { "compartment": "compartment_70101", "id": "reaction_10770795", "reactome": "R-SCE-450400", "name": "ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770791", "species_450597", "species_10770767" ], "products": [ "species_10770793" ], "modifiers": [], "additional_components": [ "P47976", "YDR151C", "P47977", "YLR136C", "YBR017C", "P47976", "YDR151C", "P38217", "YBR017C", "P47977", "YLR136C" ] }, "reaction_10770820": { "compartment": "compartment_70101", "id": "reaction_10770820", "reactome": "R-SCE-450474", "name": "MK2 phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770810", "species_113592" ], "products": [ "species_29370", "species_10770818" ], "modifiers": [ [ "species_10766447", "catalyst" ] ], "additional_components": [ "P47976", "YDR151C", "P47976", "YDR151C", "YKL171W" ] }, "reaction_10770839": { "compartment": "compartment_70101", "id": "reaction_10770839", "reactome": "R-SCE-450517", "name": "Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770808", "species_450523" ], "products": [ "species_10770810" ], "modifiers": [], "additional_components": [ "YDR151C", "P47976", "YDR151C" ] }, "reaction_10768801": { "compartment": "compartment_70101", "id": "reaction_10768801", "reactome": "R-SCE-381111", "name": "EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10762638", "species_113592" ], "products": [ "species_29370", "species_10768798" ], "modifiers": [ [ "species_10768776", "catalyst" ] ], "additional_components": [ "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "P32481", "GCD11", "P09064", "SUI3", "P20459", "phospho-SUI2", "P47042", "YJL057C" ] }, "reaction_10768778": { "compartment": "compartment_12045", "id": "reaction_10768778", "reactome": "R-SCE-381087", "name": "Dimerization of PERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768767" ], "products": [ "species_10768776" ], "modifiers": [], "additional_components": [ "YJL057C", "P47042", "YJL057C" ] }, "reaction_10771292": { "compartment": "compartment_70101", "id": "reaction_10771292", "reactome": "R-SCE-888592", "name": "Loading of GABA into clathrin sculpted GABA transport vesicle lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352011" ], "products": [ "species_428571" ], "modifiers": [ [ "species_10771289", "catalyst" ] ], "additional_components": [ "YJR001W" ] }, "reaction_10771287": { "compartment": "compartment_5460", "id": "reaction_10771287", "reactome": "R-SCE-888548", "name": "ALDH5A1 dehydrogenates SUCCSA to SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_880046", "species_113526" ], "products": [ "species_113536", "species_29362", "species_113529" ], "modifiers": [ [ "species_10771284", "catalyst" ] ], "additional_components": [ "P38067", "YBR006W" ] }, "reaction_10771335": { "compartment": "compartment_5460", "id": "reaction_10771335", "reactome": "R-SCE-916855", "name": "PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_916850" ], "products": [ "species_113552", "species_880046" ], "modifiers": [ [ "species_10771332", "catalyst" ] ], "additional_components": [ "CHEBI:33739", "P17649", "YGR019W" ] }, "reaction_10777469": { "compartment": "compartment_70101", "id": "reaction_10777469", "reactome": "R-SCE-5324632", "name": "Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10777464", "species_5324631" ], "products": [ "species_10775732", "species_10775828", "species_10768212", "species_10777466" ], "modifiers": [ [ "species_10777464", "catalyst" ] ], "additional_components": [ "P02829", "YPL240C", "P53973", "YNL021W", "P28707", "YKL117W", "P38889", "YHR206W", "P10961", "YGL073W", "P15108", "YMR186W", "P25694", "YDL126C", "P38889", "YHR206W", "P10961", "YGL073W", "P02829", "YPL240C", "P15108", "YMR186W", "YKL117W", "P53973", "YNL021W", "P25694", "YDL126C", "P02829", "YPL240C", "P53973", "YNL021W", "P28707", "YKL117W", "P38889", "YHR206W", "P10961", "YGL073W", "P15108", "YMR186W", "P25694", "YDL126C" ] }, "reaction_10775838": { "compartment": "compartment_7660", "id": "reaction_10775838", "reactome": "R-SCE-3371518", "name": "SIRT1 binds to HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775800", "species_10769730" ], "products": [ "species_10775802" ], "modifiers": [], "additional_components": [ "P36016", "YKL073W", "P25294", "YNL007C", "P22202", "YER103W", "P38889", "YHR206W", "P10961", "YGL073W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "YDL042C", "P36016", "YKL073W", "P25294", "YNL007C", "P06700", "YDL042C", "P22202", "YER103W", "P38889", "YHR206W", "P10961", "YGL073W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C" ] }, "reaction_10776963": { "compartment": "compartment_7660", "id": "reaction_10776963", "reactome": "R-SCE-5082409", "name": "Dissociation of HSF1:HSP90 complex in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776961" ], "products": [ "species_10776953", "species_10776959", "species_10776931" ], "modifiers": [], "additional_components": [ "P02829", "YPL240C", "P28707", "YKL117W", "P38889", "YHR206W", "P10961", "YGL073W", "P15108", "YMR186W", "YKL117W", "P02829", "YPL240C", "P15108", "YMR186W", "P38889", "YHR206W", "P10961", "YGL073W" ] }, "reaction_10776071": { "compartment": "compartment_70101", "id": "reaction_10776071", "reactome": "R-SCE-3697860", "name": "SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776067", "species_10775367" ], "products": [ "species_10776069" ], "modifiers": [], "additional_components": [ "species_158417", "CHEBI:49552", "P40202", "CCS1", "species_158417", "P00445", "SOD1", "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1" ] }, "reaction_10776933": { "compartment": "compartment_7660", "id": "reaction_10776933", "reactome": "R-SCE-5082391", "name": "Trimerization of HSF1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776931" ], "products": [ "species_10775810" ], "modifiers": [], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W" ] }, "reaction_10787563": { "compartment": "compartment_70101", "id": "reaction_10787563", "reactome": "R-SCE-8951723", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776069" ], "products": [ "species_10775369" ], "modifiers": [], "additional_components": [ "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1", "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1" ] }, "reaction_10775817": { "compartment": "compartment_7660", "id": "reaction_10775817", "reactome": "R-SCE-3371467", "name": "SIRT1 deacetylates HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_427523", "species_10775802" ], "products": [ "species_427498", "species_427497", "species_10775814", "species_10769730" ], "modifiers": [ [ "species_10775802", "catalyst" ] ], "additional_components": [ "P36016", "YKL073W", "P25294", "YNL007C", "P06700", "YDL042C", "P22202", "YER103W", "P38889", "YHR206W", "P10961", "YGL073W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P36016", "YKL073W", "P25294", "YNL007C", "P22202", "YER103W", "P38889", "YHR206W", "P09435", "YBL075C", "P10592", "YLL024C", "P10961", "YGL073W", "P10591", "YAL005C", "YDL042C", "P36016", "YKL073W", "P25294", "YNL007C", "P06700", "YDL042C", "P22202", "YER103W", "P38889", "YHR206W", "P10961", "YGL073W", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C" ] }, "reaction_10775358": { "compartment": "compartment_70101", "id": "reaction_10775358", "reactome": "R-SCE-3299691", "name": "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_1222424" ], "products": [ "species_29408", "species_29368" ], "modifiers": [ [ "species_10775355", "catalyst" ] ], "additional_components": [ "species_158417", "P00445", "SOD1", "species_437295" ] }, "reaction_10776951": { "compartment": "compartment_7660", "id": "reaction_10776951", "reactome": "R-SCE-5082405", "name": "Phosphorylation of HSF1 at Ser326 induces transactivation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775810", "species_29358" ], "products": [ "species_113582", "species_10776917" ], "modifiers": [ [ "species_10776948", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "P32600", "YKL203C", "P41318", "YNL006W", "P38873", "YHR186C" ] }, "reaction_10775376": { "compartment": "compartment_70101", "id": "reaction_10775376", "reactome": "R-SCE-3299753", "name": "CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775369" ], "products": [ "species_10775373", "species_10775355" ], "modifiers": [ [ "species_10775369", "catalyst" ] ], "additional_components": [ "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1", "species_158417", "CHEBI:49552", "P40202", "CCS1", "species_158417", "P00445", "SOD1", "species_437295", "species_158417", "P00445", "SOD1", "CHEBI:49552", "P40202", "CCS1" ] }, "reaction_10776841": { "compartment": "compartment_70101", "id": "reaction_10776841", "reactome": "R-SCE-4793911", "name": "MAPKAPK2 phosphorylates HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775732", "species_113592" ], "products": [ "species_29370", "species_10776838" ], "modifiers": [ [ "species_10766440", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "YKL171W" ] }, "reaction_10777933": { "compartment": "compartment_70101", "id": "reaction_10777933", "reactome": "R-SCE-5618107", "name": "ATP binding to HSP90 triggers conformation change", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10775834" ], "products": [ "species_10777927" ], "modifiers": [], "additional_components": [ "P36016", "YKL073W", "P02829", "YPL240C", "P22202", "YER103W", "species_29370", "P15705", "YOR027W", "P09435", "YBL075C", "P10592", "YLL024C", "P15108", "YMR186W", "P10591", "YAL005C", "P36016", "YKL073W", "P02829", "YPL240C", "P22202", "YER103W", "P15705", "YOR027W", "species_29370", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P15108", "YMR186W", "P10591", "YAL005C" ] }, "reaction_10788859": { "compartment": "compartment_17938", "id": "reaction_10788859", "reactome": "R-SCE-9640195", "name": "RRAGA,B hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788854" ], "products": [ "species_10788856", "species_29372" ], "modifiers": [ [ "species_10788854", "catalyst" ] ], "additional_components": [ "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P25378", "YCR027C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P25378", "YCR027C", "species_29438", "P38873", "YHR186C", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P32600", "YKL203C", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P25378", "YCR027C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10776883": { "compartment": "compartment_17963", "id": "reaction_10776883", "reactome": "R-SCE-4837364", "name": "Secretion of SOD3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776881" ], "products": [ "species_10775345" ], "modifiers": [], "additional_components": [ "species_158417", "P00445", "SOD1", "species_437295", "species_158417", "P00445", "SOD1", "species_437295" ] }, "reaction_10764183": { "compartment": "compartment_17951", "id": "reaction_10764183", "reactome": "R-SCE-76031", "name": "2 H2O2 => O2 + 2 H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113575" ], "products": [ "species_141343", "species_113535" ], "modifiers": [ [ "species_10764180", "catalyst" ] ], "additional_components": [ "P15202", "YDR256C", "species_189444", "species_113602" ] }, "reaction_10788844": { "compartment": "compartment_17938", "id": "reaction_10788844", "reactome": "R-SCE-9639286", "name": "RRAGC,D exchanges GTP for GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788837", "species_29420" ], "products": [ "species_29438", "species_10788841" ], "modifiers": [ [ "species_10788837", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10775629": { "compartment": "compartment_70616", "id": "reaction_10775629", "reactome": "R-SCE-3341294", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_10765569" ], "products": [ "species_10765567", "species_189461" ], "modifiers": [], "additional_components": [ "P00045", "YEL039C", "P00044", "YJR048W", "CHEBI:38574", "P00045", "YEL039C", "P00044", "YJR048W", "CHEBI:38573" ] }, "reaction_10788899": { "compartment": "compartment_17938", "id": "reaction_10788899", "reactome": "R-SCE-9646468", "name": "mTORC1 binds RHEB:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10765837", "species_10788852" ], "products": [ "species_10788854" ], "modifiers": [], "additional_components": [ "P25378", "YCR027C", "species_29438", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P25378", "YCR027C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10775719": { "compartment": "compartment_70101", "id": "reaction_10775719", "reactome": "R-SCE-3371422", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775714" ], "products": [ "species_29372", "species_10775716" ], "modifiers": [ [ "species_10775714", "catalyst" ], [ "species_10775712", "catalyst" ] ], "additional_components": [ "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_29370", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W" ] }, "reaction_10776175": { "compartment": "compartment_17927", "id": "reaction_10776175", "reactome": "R-SCE-3777112", "name": "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_163953" ], "products": [ "species_189481", "species_189461" ], "modifiers": [ [ "species_10776172", "catalyst" ] ], "additional_components": [ "species_158417", "P00445", "SOD1", "species_437295" ] }, "reaction_10775836": { "compartment": "compartment_70101", "id": "reaction_10775836", "reactome": "R-SCE-3371503", "name": "STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775828", "species_10775822", "species_10775716" ], "products": [ "species_10775712", "species_10775834" ], "modifiers": [], "additional_components": [ "P02829", "YPL240C", "P15108", "YMR186W", "YOR027W", "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_29370", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P36016", "YKL073W", "P02829", "YPL240C", "P22202", "YER103W", "species_29370", "P15705", "YOR027W", "P09435", "YBL075C", "P10592", "YLL024C", "P15108", "YMR186W", "P10591", "YAL005C" ] }, "reaction_10775760": { "compartment": "compartment_70101", "id": "reaction_10775760", "reactome": "R-SCE-3371435", "name": "Constitutive phosphorylation by GSK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775732", "species_113592" ], "products": [ "species_29370", "species_10775740" ], "modifiers": [ [ "species_10775757", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "P50873", "YDL079C", "P38615", "YMR139W", "P21965", "YNL307C" ] }, "reaction_10775348": { "compartment": "compartment_984", "id": "reaction_10775348", "reactome": "R-SCE-3299682", "name": "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3299686", "species_351626" ], "products": [ "species_351629", "species_352327" ], "modifiers": [ [ "species_10775345", "catalyst" ] ], "additional_components": [ "species_158417", "P00445", "SOD1", "species_437295" ] }, "reaction_10775848": { "compartment": "compartment_70101", "id": "reaction_10775848", "reactome": "R-SCE-3371527", "name": "HSF1 trimer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775846" ], "products": [ "species_10775810" ], "modifiers": [], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W" ] }, "reaction_10775875": { "compartment": "compartment_70101", "id": "reaction_10775875", "reactome": "R-SCE-3371590", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775871", "species_10775873" ], "products": [ "species_10775714" ], "modifiers": [], "additional_components": [ "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P36016", "YKL073W", "P22202", "YER103W", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C", "P36016", "YKL073W", "P25491", "YNL064C", "P25294", "YNL007C", "P53940", "YNL077W", "P22202", "YER103W", "species_113592", "P09435", "YBL075C", "P10592", "YLL024C", "P10591", "YAL005C" ] }, "reaction_10775865": { "compartment": "compartment_70101", "id": "reaction_10775865", "reactome": "R-SCE-3371531", "name": "Constitutive phosphorylation by pERK1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775732", "species_113592" ], "products": [ "species_29370", "species_10775856" ], "modifiers": [ [ "species_10775862", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10775869": { "compartment": "compartment_70101", "id": "reaction_10775869", "reactome": "R-SCE-3371586", "name": "Dissociation of cytosolic HSF1:HSP90 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775867" ], "products": [ "species_10775732", "species_10775828", "species_10768212" ], "modifiers": [], "additional_components": [ "P02829", "YPL240C", "P28707", "YKL117W", "P38889", "YHR206W", "P10961", "YGL073W", "P15108", "YMR186W", "P38889", "YHR206W", "P10961", "YGL073W", "P02829", "YPL240C", "P15108", "YMR186W", "YKL117W" ] }, "reaction_10788872": { "compartment": "compartment_17938", "id": "reaction_10788872", "reactome": "R-SCE-9645598", "name": "RRAGC,D hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788837" ], "products": [ "species_10788841", "species_29372" ], "modifiers": [ [ "species_10788837", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10776919": { "compartment": "compartment_7660", "id": "reaction_10776919", "reactome": "R-SCE-5082356", "name": "HSF1-mediated gene expression", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775812" ], "products": [ "species_10776897" ], "modifiers": [ [ "species_10776907", "catalyst" ], [ "species_10776917", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P25294", "YNL007C", "P02829", "YPL240C", "P10592", "YLL024C", "P15108", "YMR186W", "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W" ] }, "reaction_10788874": { "compartment": "compartment_17938", "id": "reaction_10788874", "reactome": "R-SCE-9645608", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788848", "species_10788850" ], "products": [ "species_10788852" ], "modifiers": [], "additional_components": [ "P32600", "YKL203C", "P41318", "YNL006W", "P38873", "YHR186C", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W", "P41318", "YNL006W", "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "species_29438", "P32366", "YLR447C", "P38873", "YHR186C", "P25515", "YEL027W", "species_29420", "P53290", "YGR163W", "P23968", "YHR026W", "P32600", "YKL203C", "Q00582", "YML121W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10775877": { "compartment": "compartment_70101", "id": "reaction_10775877", "reactome": "R-SCE-3371591", "name": "Trimerization of cytosolic HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775732" ], "products": [ "species_10775846" ], "modifiers": [ [ "species_10765400", "catalyst" ] ], "additional_components": [ "P38889", "YHR206W", "P10961", "YGL073W", "P38889", "YHR206W", "P10961", "YGL073W", "P32769", "YKR084C", "P02994", "YBR118W", "Q08491", "SKI7" ] }, "reaction_10775337": { "compartment": "compartment_5460", "id": "reaction_10775337", "reactome": "R-SCE-3299680", "name": "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3299683", "species_113529" ], "products": [ "species_113533", "species_1614617" ], "modifiers": [ [ "species_10775334", "catalyst" ] ], "additional_components": [ "P00447", "YHR008C", "species_113527" ] }, "reaction_10775625": { "compartment": "compartment_5460", "id": "reaction_10775625", "reactome": "R-SCE-3323079", "name": "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_1655882", "species_113529" ], "products": [ "species_113563", "species_1655887" ], "modifiers": [ [ "species_10775622", "catalyst" ] ], "additional_components": [ "P41921", "YPL091W", "species_113596" ] }, "reaction_10769335": { "compartment": "compartment_70101", "id": "reaction_10769335", "reactome": "R-SCE-418456", "name": "cGMP is degraded by PDEs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30991" ], "products": [ "species_113578" ], "modifiers": [ [ "species_10769328", "catalyst" ] ], "additional_components": [ "YOR360C" ] }, "reaction_10788618": { "compartment": "compartment_70101", "id": "reaction_10788618", "reactome": "R-SCE-9610166", "name": "p-T,Y MAPK dimers translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775862" ], "products": [ "species_10767244" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10778778": { "compartment": "compartment_70101", "id": "reaction_10778778", "reactome": "R-SCE-5674385", "name": "p-T,Y MAPKs dimerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772586" ], "products": [ "species_10775862" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10788635": { "compartment": "compartment_7660", "id": "reaction_10788635", "reactome": "R-SCE-9612509", "name": "SGK phosphorylates SRF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10788623" ], "products": [ "species_113582", "species_10788626" ], "modifiers": [ [ "species_10788632", "catalyst" ] ], "additional_components": [ "YMR043W", "YMR043W", "P12688", "YKL126W", "P11792", "YHR205W" ] }, "reaction_10771748": { "compartment": "compartment_70101", "id": "reaction_10771748", "reactome": "R-SCE-927889", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771743", "species_113592" ], "products": [ "species_29370", "species_10771745" ], "modifiers": [ [ "species_10771743", "catalyst" ] ], "additional_components": [ "P10622", "YDL130W", "P38798", "YHR077C", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P38760", "YHR015W", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P12385", "SUP45", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P04147", "YER165W", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P39684", "YFR023W", "P38061", "RPL32", "P14120", "RPL30", "species_29420", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P39936", "YGL049C", "P0CX82", "RPL19A", "Q12099", "YDR021W", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P05453", "SUP35", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P48412", "YGR072W", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "Q08920", "YPL178W", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P30771", "YMR080C", "P34160", "YMR125W", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771730" ], "products": [ "species_10771693" ], "modifiers": [ [ "species_10771730", "catalyst" ] ], "additional_components": [ "P10622", "YDL130W", "P38798", "YHR077C", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "P40456", "YIL151C", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P17214", "YLR233C", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P38760", "YHR015W", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P12385", "SUP45", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P04147", "YER165W", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "Q03466", "YDR206W", "P39684", "YFR023W", "P38061", "RPL32", "P14120", "RPL30", "species_29420", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771633", "species_10771609" ], "products": [ "species_10771635" ], "modifiers": [], "additional_components": [ "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P38760", "YHR015W", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P12385", "SUP45", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P04147", "YER165W", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P39684", "YFR023W", "P38061", "RPL32", "P14120", "RPL30", "species_29420", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P39936", "YGL049C", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P05453", "SUP35", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "Q08920", "YPL178W", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P34160", "YMR125W", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B", "YMR080C", "P10622", "YDL130W", "P0CX84", "RPL35A", "P0CX41", "RPL23A", "P38754", "RPL14B", "O14455", "RPL36B", "P0CX54", "RPL12B", "P51401", "RPL9B", "P0CX46", "RPL2B", "Q02753", "RPL21A", "P29453", "RPL8B", "P49167", "RPL38", "P0C0W1", "RPS22A", "P0CX42", "RPL23B", "P10664", "RPL4A", "P0CX48", "RPS11B", "P05756", "RPS13", "P38760", "YHR015W", "P54780", "RPL15B", "P41057", "RPS29A", "P39938", "RPS26A", "P12385", "SUP45", "P0C0W9", "RPL11A", "P0CH09", "RPL40B", "P04147", "YER165W", "P0CX39", "RPS8A", "P07280", "RPS19A", "P39516", "RPS14B", "P41805", "RPL10", "P39684", "YFR023W", "P38061", "RPL32", "P14120", "RPL30", "species_29420", "P0CX24", "RPL20B", "P0CX85", "RPL35B", "P0CX43", "RPL1A", "P0CX47", "RPS11A", "P0CX53", "RPL12A", "P39936", "YGL049C", "P0CX82", "RPL19A", "P0CX56", "RPS18B", "P26786", "RPS7A", "P0CX36", "RPS4B", "P0CX29", "RPS23A", "P05453", "SUP35", "Q3E757", "RPL11B", "P07281", "RPS19B", "P38701", "RPS20", "P05750", "RPS3", "P39935", "YGR162W", "P0CX40", "RPS8B", "P51402", "RPL37B", "P0C2H9", "RPL31B", "P05748", "RPL15A", "P0CX83", "RPL19B", "P26321", "RPL5", "P25443", "RPS2", "P0CX55", "RPS18A", "P48589", "RPS12", "Q3E792", "RPS25A", "P32905", "RPS0A", "P0CX51", "RPS16A", "P0CX23", "RPL20A", "Q08920", "YPL178W", "P14126", "RPL3", "P0CH08", "RPL40A", "P0CX31", "RPS24A", "P53221", "RPL26B", "P05755", "RPS9B", "P0C0X0", "RPS28B", "P05740", "RPL17A", "P0CX37", "RPS6A", "P0CX27", "RPL42A", "P38711", "RPS27B", "P0CX44", "RPL1B", "P0CX30", "RPS23B", "P30771", "YMR080C", "P34160", "YMR125W", "P0CX28", "RPL42B", "P05744", "RPL33A", "P26783", "RPS5", "P05759", "RPS31", "P02406", "RPL28", "Q3E754", "RPS21B", "P0CX38", "RPS6B", "P0CX52", "RPS16B", "P04449", "RPL24A", "P35997", "RPS27A", "P0CX50", "RPL18B", "Q08745", "RPS10A", "P46784", "RPS10B", "P0CX49", "RPL18A", "P06367", "RPS14A", "P0CX45", "RPL2A", "P0CX32", "RPS24B", "P05737", "RPL7A", "P26784", "RPL16A", "P0C2H6", "RPL27A", "P05317", "YLR340W", "P0CX35", "RPS4A", "P04650", "RPL39", "P56628", "RPL22B", "P0C2H8", "RPL31A", "P23248", "RPS1B", "P49166", "RPL37A", "P05749", "RPL22A", "P40212", "RPL13B", "P05747", "RPL29", "P04456", "RPL25", "Q01855", "RPS15", "P02400", "RPP2B", "P49626", "RPL4B", "P14127", "RPS17B", "P05743", "RPL26A", "P05739", "RPL6B" ] }, "reaction_10777503": { "compartment": "compartment_263163", "id": "reaction_10777503", "reactome": "R-SCE-5333658", "name": "CLAT:AP1:CLVS bind PI(3,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5334668", "species_10777499" ], "products": [ "species_10777501" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P36000", "YKL135C", "Q12028", "YPR029C", "P22137", "YGL206C", "Q00776", "YPL259C", "P35181", "YLR170C", "species_6809774", "P17891", "YGR167W", "P36000", "YKL135C", "Q12028", "YPR029C", "P22137", "YGL206C", "Q00776", "YPL259C", "P35181", "YLR170C" ] }, "reaction_10764574": { "compartment": "compartment_70101", "id": "reaction_10764574", "reactome": "R-SCE-109857", "name": "MAP2K1 binds MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764553", "species_10764570" ], "products": [ "species_10764572" ], "modifiers": [], "additional_components": [ "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10764621": { "compartment": "compartment_70101", "id": "reaction_10764621", "reactome": "R-SCE-109863", "name": "Dissociation of p-T,Y-MAPK3:MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764600" ], "products": [ "species_10764553", "species_10764598" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10786323": { "compartment": "compartment_70101", "id": "reaction_10786323", "reactome": "R-SCE-8866275", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786276", "species_10786319" ], "products": [ "species_10786321" ], "modifiers": [], "additional_components": [ "YMR276W", "Q07872", "YLL038C", "Q05785", "YLR206W", "P34216", "YBL047C", "P39013", "YNL084C", "Q03769", "YDR153C", "P47160", "YJR125C", "P32521", "YIR006C", "Q12518", "YDL161W", "Q07872", "YLL038C", "Q05785", "YLR206W", "P34216", "YBL047C", "P39013", "YNL084C", "P48510", "YMR276W", "Q03769", "YDR153C", "P47160", "YJR125C", "P32521", "YIR006C", "Q12518", "YDL161W" ] }, "reaction_10786337": { "compartment": "compartment_876", "id": "reaction_10786337", "reactome": "R-SCE-8866277", "name": "AP-2 directly binds some endocytic cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786331", "species_10786030" ], "products": [ "species_10786333" ], "modifiers": [ [ "species_10786335", "inhibitor" ] ], "additional_components": [ "P0CE68", "YKR103W", "P12866", "YKL209C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "Q00381", "YJR058C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "P0CE68", "YKR103W", "Q00381", "YJR058C", "P12866", "YKL209C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "species_9648300", "Q00381", "YJR058C" ] }, "reaction_10786206": { "compartment": "compartment_70101", "id": "reaction_10786206", "reactome": "R-SCE-8863727", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10781023", "species_10786204" ], "products": [ "species_10786190" ], "modifiers": [], "additional_components": [ "YDR139C", "Q99186", "YOL062C", "P38700", "YHL019C", "Q99186", "YOL062C", "P38700", "YHL019C" ] }, "reaction_10786140": { "compartment": "compartment_876", "id": "reaction_10786140", "reactome": "R-SCE-8856813", "name": "AAK1 phosphorylates AP-2 mu subunit at T156", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10786130" ], "products": [ "species_29370", "species_10786137" ], "modifiers": [ [ "species_10786130", "catalyst" ] ], "additional_components": [ "P25623", "YCR030C", "P17891", "YGR167W", "P53974", "YNL020C", "P36000", "YKL135C", "P34216", "YBL047C", "P38065", "YBL037W", "P38080", "YBR059C", "Q00381", "YJR058C", "Q05080", "YMR032W", "P39013", "YNL084C", "P27351", "YJR005W", "P43556", "YFL047W", "P22137", "YGL206C", "Q99186", "YOL062C", "P32521", "YIR006C", "P40494", "YIL095W", "species_179856", "P25623", "YCR030C", "P17891", "YGR167W", "P53974", "YNL020C", "P36000", "YKL135C", "P34216", "YBL047C", "P38065", "YBL037W", "P38080", "YBR059C", "Q00381", "YJR058C", "Q05080", "YMR032W", "P39013", "YNL084C", "P27351", "YJR005W", "P43556", "YFL047W", "P22137", "YGL206C", "Q99186", "YOL062C", "P32521", "YIR006C", "P40494", "YIL095W", "species_179856", "P25623", "YCR030C", "P17891", "YGR167W", "P53974", "YNL020C", "P36000", "YKL135C", "P34216", "YBL047C", "P38065", "YBL037W", "P38080", "YBR059C", "Q00381", "YJR058C", "Q05080", "YMR032W", "P39013", "YNL084C", "P27351", "YJR005W", "P43556", "YFL047W", "P22137", "YGL206C", "Q99186", "YOL062C", "P32521", "YIR006C", "P40494", "YIL095W", "species_179856" ] }, "reaction_10786527": { "compartment": "compartment_876", "id": "reaction_10786527", "reactome": "R-SCE-8868066", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10773422", "catalyst" ] ], "additional_components": [ "YDR208W" ] }, "reaction_10786779": { "compartment": "compartment_876", "id": "reaction_10786779", "reactome": "R-SCE-8871196", "name": "Initial binding of AP-2 and clathrin to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769532", "species_179856", "species_10786030" ], "products": [ "species_10786116" ], "modifiers": [], "additional_components": [ "P17891", "YGR167W", "P22137", "YGL206C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "Q00381", "YJR058C", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "species_179856" ] }, "reaction_10786466": { "compartment": "compartment_876", "id": "reaction_10786466", "reactome": "R-SCE-8867613", "name": "PICALM binds R-SNAREs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786449", "species_10786462" ], "products": [ "species_10786464" ], "modifiers": [], "additional_components": [ "P33328", "YOR327C", "P31109", "YAL030W", "P38856", "YHR161C", "P53309", "YGR241C", "P38856", "YHR161C", "P53309", "YGR241C", "P33328", "YOR327C", "P31109", "YAL030W" ] }, "reaction_10789079": { "compartment": "compartment_70101", "id": "reaction_10789079", "reactome": "R-SCE-9681616", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9648300", "species_10786030" ], "products": [ "species_10786335" ], "modifiers": [], "additional_components": [ "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "Q00381", "YJR058C", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "Q99186", "YOL062C", "species_9648300", "Q00381", "YJR058C" ] }, "reaction_10786167": { "compartment": "compartment_876", "id": "reaction_10786167", "reactome": "R-SCE-8862280", "name": "FCHo proteins bind nascent clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10786094", "species_10786063", "species_10786116", "species_10786110", "species_10786102", "species_10786124" ], "products": [ "species_10786126" ], "modifiers": [], "additional_components": [ "P25623", "YCR030C", "Q05080", "YMR032W", "P43556", "YFL047W", "P34216", "YBL047C", "P39013", "YNL084C", "P32521", "YIR006C", "P17891", "YGR167W", "P36000", "YKL135C", "P38065", "YBL037W", "P27351", "YJR005W", "P22137", "YGL206C", "Q99186", "YOL062C", "Q00381", "YJR058C", "species_179856", "P34216", "YBL047C", "P39013", "YNL084C", "P32521", "YIR006C", "P34216", "YBL047C", "P39013", "YNL084C", "P32521", "YIR006C", "P25623", "YCR030C", "Q05080", "YMR032W", "P43556", "YFL047W", "P17891", "YGR167W", "P25623", "YCR030C", "P36000", "YKL135C", "P38065", "YBL037W", "P34216", "YBL047C", "Q00381", "YJR058C", "P27351", "YJR005W", "Q05080", "YMR032W", "P39013", "YNL084C", "P22137", "YGL206C", "Q99186", "YOL062C", "P43556", "YFL047W", "P32521", "YIR006C", "species_179856" ] }, "reaction_10765839": { "compartment": "compartment_17938", "id": "reaction_10765839", "reactome": "R-SCE-165195", "name": "GTP loading by Rheb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10765835" ], "products": [ "species_10765837", "species_29420" ], "modifiers": [], "additional_components": [ "species_29420", "P25378", "YCR027C", "P25378", "YCR027C", "species_29438" ] }, "reaction_10778419": { "compartment": "compartment_70101", "id": "reaction_10778419", "reactome": "R-SCE-5653957", "name": "Rag dimer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778402", "species_10778415" ], "products": [ "species_10778417" ], "modifiers": [], "additional_components": [ "Q00582", "YML121W", "species_29438", "species_29420", "P53290", "YGR163W", "species_29420", "P53290", "YGR163W", "Q00582", "YML121W", "species_29438" ] }, "reaction_10768750": { "compartment": "compartment_70101", "id": "reaction_10768750", "reactome": "R-SCE-380930", "name": "Phosphorylated AMPK binds AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767428", "species_76577" ], "products": [ "species_10768748" ], "modifiers": [], "additional_components": [ "P36002", "YKL198C", "P34164", "YGL208W", "Q04739", "YER027C", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C", "P36002", "YKL198C", "P34164", "YGL208W", "Q04739", "YER027C", "species_76577", "P47116", "YJR059W", "P32578", "YDR422C", "P06782", "YDR477W", "P12904", "YGL115W", "P38845", "YHR146W", "P53885", "YNL173C" ] }, "reaction_10787858": { "compartment": "compartment_5460", "id": "reaction_10787858", "reactome": "R-SCE-8986181", "name": "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10787850" ], "products": [], "modifiers": [ [ "species_10787855", "catalyst" ] ], "additional_components": [ "P53193", "JAC1", "P05150", "YJL088W", "Q07540", "YFH1", "P19882", "HSP60", "YDR430C" ] }, "reaction_10773966": { "compartment": "compartment_70616", "id": "reaction_10773966", "reactome": "R-SCE-1955380", "name": "TIMM9:TIMM10 transfers proteins to TIMM22", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10773936", "species_10773958", "species_10773960" ], "products": [ "species_10773964" ], "modifiers": [], "additional_components": [ "P32897", "TIM23", "P18238", "YBR085W", "P18239", "YBL030C", "O74700", "TIM9", "P39515", "TIM17", "Q12328", "TIM22", "P87108", "TIM10", "Q06510", "TAZ1", "P04710", "AAC1", "P32897", "TIM23", "P18238", "YBR085W", "P18239", "YBL030C", "O74700", "TIM9", "P39515", "TIM17", "Q12328", "TIM22", "Q06510", "TAZ1", "P87108", "TIM10", "P04710", "AAC1" ] }, "reaction_10787754": { "compartment": "compartment_70101", "id": "reaction_10787754", "reactome": "R-SCE-8981553", "name": "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10787751", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10771210": { "compartment": "compartment_20699", "id": "reaction_10771210", "reactome": "R-SCE-742354", "name": "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756" ], "products": [ "species_914003" ], "modifiers": [ [ "species_10771207", "catalyst" ] ], "additional_components": [ "YEL004W" ] }, "reaction_10777534": { "compartment": "compartment_70101", "id": "reaction_10777534", "reactome": "R-SCE-5339538", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10777531", "catalyst" ] ], "additional_components": [ "P48439", "YOR085W", "Q03723", "YML019W" ] }, "reaction_10787772": { "compartment": "compartment_70101", "id": "reaction_10787772", "reactome": "R-SCE-8981574", "name": "GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10766510", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10777511": { "compartment": "compartment_70101", "id": "reaction_10777511", "reactome": "R-SCE-5336466", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29926" ], "products": [ "species_109496" ], "modifiers": [ [ "species_10777508", "catalyst" ] ], "additional_components": [ "YPL060W" ] }, "reaction_10770623": { "compartment": "compartment_70101", "id": "reaction_10770623", "reactome": "R-SCE-450092", "name": "GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10770619" ], "products": [ "species_113592", "species_10770617" ], "modifiers": [], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C", "species_113592", "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10787104": { "compartment": "compartment_70101", "id": "reaction_10787104", "reactome": "R-SCE-8932851", "name": "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8932838" ], "products": [ "species_8932842" ], "modifiers": [ [ "species_10787101", "catalyst" ] ], "additional_components": [ "CHEBI:32513", "species_1131871", "species_29468", "CHEBI:32513", "species_1131871", "species_29468", "YOL092W" ] }, "reaction_10771591": { "compartment": "compartment_74700", "id": "reaction_10771591", "reactome": "R-SCE-917841", "name": "Acidification of Tf:TfR1 containing endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113592", "species_29356" ], "products": [ "species_29370", "species_74722", "species_29372" ], "modifiers": [ [ "species_10763690", "catalyst" ] ], "additional_components": [ "P48836", "YHR039C-A", "P32563", "YOR270C", "P39111", "YGR020C", "P32366", "YLR447C", "P25515", "YEL027W", "P23968", "YHR026W", "P16140", "YBR127C", "P41807", "YPR036W", "P22203", "YOR332W", "P37296", "YMR054W", "Q3E7B6", "YCL005W-A", "P17255", "YDL185W", "P31412", "YKL080W", "P32610", "YEL051W" ] }, "reaction_10771200": { "compartment": "compartment_20699", "id": "reaction_10771200", "reactome": "R-SCE-727759", "name": "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183" ], "products": [ "species_727753" ], "modifiers": [ [ "species_10771197", "catalyst" ] ], "additional_components": [ "YBR220C" ] }, "reaction_10770621": { "compartment": "compartment_70101", "id": "reaction_10770621", "reactome": "R-SCE-450088", "name": "GLUT1 tetramer binds 4xATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10770617" ], "products": [ "species_10770619" ], "modifiers": [], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C", "P38142", "YBR241C", "P53142", "YGL104C", "species_113592" ] }, "reaction_10769976": { "compartment": "compartment_876", "id": "reaction_10769976", "reactome": "R-SCE-429036", "name": "SLC2A9 transports Fru, Glc, urate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429078" ], "products": [ "species_429148" ], "modifiers": [ [ "species_10769973", "catalyst" ] ], "additional_components": [ "species_70113", "species_29532", "CHEBI:17775", "species_70113", "species_29532", "CHEBI:17775", "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10771269": { "compartment": "compartment_876", "id": "reaction_10771269", "reactome": "R-SCE-879575", "name": "SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879603" ], "products": [ "species_879628" ], "modifiers": [ [ "species_10771266", "catalyst" ] ], "additional_components": [ "CHEBI:18332", "CHEBI:28774", "CHEBI:18332", "CHEBI:28774", "P25568", "YCL038C", "P53918", "YNL125C", "Q08777", "YOR306C", "Q08268", "YOL119C", "P36032", "YKL221W" ] }, "reaction_10777522": { "compartment": "compartment_70101", "id": "reaction_10777522", "reactome": "R-SCE-5339528", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10777519", "catalyst" ] ], "additional_components": [ "YOR085W" ] }, "reaction_10787770": { "compartment": "compartment_70101", "id": "reaction_10787770", "reactome": "R-SCE-8981570", "name": "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10787767", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10769950": { "compartment": "compartment_876", "id": "reaction_10769950", "reactome": "R-SCE-428779", "name": "GLUT7 and GLUT11 transport glucose and fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428819" ], "products": [ "species_428802" ], "modifiers": [ [ "species_10769947", "catalyst" ] ], "additional_components": [ "species_70113", "species_29532", "species_70113", "species_29532", "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10770626": { "compartment": "compartment_70101", "id": "reaction_10770626", "reactome": "R-SCE-450095", "name": "GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70113" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10766510", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10771213": { "compartment": "compartment_20699", "id": "reaction_10771213", "reactome": "R-SCE-742373", "name": "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742353" ], "products": [ "species_742361" ], "modifiers": [ [ "species_10771207", "catalyst" ] ], "additional_components": [ "YEL004W" ] }, "reaction_10787759": { "compartment": "compartment_70101", "id": "reaction_10787759", "reactome": "R-SCE-8981564", "name": "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10787756", "catalyst" ] ], "additional_components": [ "P38142", "YBR241C" ] }, "reaction_10777514": { "compartment": "compartment_70101", "id": "reaction_10777514", "reactome": "R-SCE-5339524", "name": "GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10770617", "catalyst" ], [ "species_113592", "inhibitor" ] ], "additional_components": [ "P38142", "YBR241C", "P53142", "YGL104C" ] }, "reaction_10787519": { "compartment": "compartment_70616", "id": "reaction_10787519", "reactome": "R-SCE-8949688", "name": "SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8949220", "species_2889072" ], "products": [ "species_8949232", "species_2889083" ], "modifiers": [ [ "species_10787516", "catalyst" ] ], "additional_components": [ "YJR106W" ] }, "reaction_10764584": { "compartment": "compartment_70101", "id": "reaction_10764584", "reactome": "R-SCE-109858", "name": "MAP2K2 binds MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764580", "species_10764578" ], "products": [ "species_10764582" ], "modifiers": [], "additional_components": [ "YBL016W", "YDL159W", "P16892", "YBL016W", "P06784", "YDL159W" ] }, "reaction_10764623": { "compartment": "compartment_70101", "id": "reaction_10764623", "reactome": "R-SCE-109864", "name": "Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10764616" ], "products": [ "species_10764578", "species_10764614" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "P06784", "YDL159W", "YDL159W", "YBL016W" ] }, "reaction_10788776": { "compartment": "compartment_70101", "id": "reaction_10788776", "reactome": "R-SCE-9635739", "name": "PTPN7 dephosphorylates p-T,Y-MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10788755", "species_29356" ], "products": [ "species_10788773", "species_29372" ], "modifiers": [ [ "species_10788755", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "P25044", "YDL230W", "Q00772", "YHR030C", "P29461", "YOR208W", "P40048", "YER075C", "P14681", "YGR040W", "P16892", "YBL016W", "P25044", "YDL230W", "Q00772", "YHR030C", "P29461", "YOR208W", "P40048", "YER075C", "P14681", "YGR040W", "P16892", "YBL016W", "P25044", "YDL230W", "Q00772", "YHR030C", "P29461", "YOR208W", "P40048", "YER075C", "P14681", "YGR040W" ] }, "reaction_10778883": { "compartment": "compartment_70101", "id": "reaction_10778883", "reactome": "R-SCE-5675376", "name": "Cytosolic DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778780", "species_29356" ], "products": [ "species_10778842", "species_29372" ], "modifiers": [ [ "species_10778880", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P40479", "YIL113W", "P38590", "YNL053W" ] }, "reaction_10778786": { "compartment": "compartment_7660", "id": "reaction_10778786", "reactome": "R-SCE-5674387", "name": "Phosphorylated MAPKs translocate into the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778780" ], "products": [ "species_10778784" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10778836": { "compartment": "compartment_7660", "id": "reaction_10778836", "reactome": "R-SCE-5675373", "name": "Nuclear DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10778784" ], "products": [ "species_113550", "species_10778795" ], "modifiers": [ [ "species_10778833", "catalyst" ] ], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P40479", "YIL113W", "P38590", "YNL053W" ] }, "reaction_10788930": { "compartment": "compartment_876", "id": "reaction_10788930", "reactome": "R-SCE-9647991", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647934", "species_10767735" ], "products": [ "species_10788928" ], "modifiers": [], "additional_components": [ "Q12354", "YLR118C", "species_9647934", "Q12354", "YLR118C" ] }, "reaction_10778776": { "compartment": "compartment_20699", "id": "reaction_10778776", "reactome": "R-SCE-5674373", "name": "MAP2Ks phosphorylate MAPK at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10778771", "species_113592" ], "products": [ "species_29370", "species_10778773" ], "modifiers": [ [ "species_10778771", "catalyst" ] ], "additional_components": [ "P06784", "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P16892", "YBL016W", "P06784", "YDL159W", "Q00772", "YHR030C", "P14681", "YGR040W", "P06784", "YDL159W", "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W" ] }, "reaction_10788926": { "compartment": "compartment_70101", "id": "reaction_10788926", "reactome": "R-SCE-9647987", "name": "FNTB inhibitors bind FNTA:FNTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9653479", "species_10788922" ], "products": [ "species_10788924" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=6531", "LigandDisplayForward?ligandId=8025", "LigandDisplayForward?ligandId=8024", "pubchem.compound:216453", "LigandDisplayForward?ligandId=8028", "LigandDisplayForward?ligandId=8026", "LigandDisplayForward?ligandId=8030", "P29703", "YKL019W", "P22007", "YDL090C", "LigandDisplayForward?ligandId=6531", "LigandDisplayForward?ligandId=8025", "P29703", "YKL019W", "LigandDisplayForward?ligandId=8024", "pubchem.compound:216453", "LigandDisplayForward?ligandId=8028", "LigandDisplayForward?ligandId=8026", "P22007", "YDL090C", "LigandDisplayForward?ligandId=8030" ] }, "reaction_10788778": { "compartment": "compartment_70101", "id": "reaction_10788778", "reactome": "R-SCE-9635743", "name": "PTPN7 binds p-T,Y-MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10775862", "species_10788753" ], "products": [ "species_10788755" ], "modifiers": [], "additional_components": [ "P16892", "YBL016W", "Q00772", "YHR030C", "P14681", "YGR040W", "P25044", "YDL230W", "P29461", "YOR208W", "P40048", "YER075C", "P16892", "YBL016W", "P25044", "YDL230W", "Q00772", "YHR030C", "P29461", "YOR208W", "P40048", "YER075C", "P14681", "YGR040W" ] }, "reaction_10785442": { "compartment": "compartment_20699", "id": "reaction_10785442", "reactome": "R-SCE-8848484", "name": "PLA2s hydrolyze phospholipids at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429785", "species_29356" ], "products": [ "species_6814303", "species_8848483" ], "modifiers": [ [ "species_10769964", "catalyst" ] ], "additional_components": [ "P39105", "YMR008C", "Q08108", "YOL011W", "P53541", "YNL012W", "Q03674", "YMR006C" ] }, "reaction_10785464": { "compartment": "compartment_20699", "id": "reaction_10785464", "reactome": "R-SCE-8849345", "name": "LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848483", "species_548819" ], "products": [ "species_76194", "species_429785" ], "modifiers": [ [ "species_10785461", "catalyst" ] ], "additional_components": [ "YOR298W" ] }, "reaction_10785255": { "compartment": "compartment_263163", "id": "reaction_10785255", "reactome": "R-SCE-6814676", "name": "SNAPs and NSF hexamer bind cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10785251" ], "products": [ "species_10785253" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "Q03322", "YDR468C", "P33328", "YOR327C", "Q04338", "YMR197C", "Q08144", "YOL018C", "Q03322", "YDR468C", "P33328", "YOR327C", "P18759", "YBR080C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P32602", "YBL050W" ] }, "reaction_10785195": { "compartment": "compartment_263163", "id": "reaction_10785195", "reactome": "R-SCE-6814088", "name": "SYS1 binds AcM-ARFRP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785165", "species_10785193" ], "products": [ "species_10785173" ], "modifiers": [], "additional_components": [ "YJL004C", "Q02804", "ARL3", "species_29438", "Q02804", "ARL3", "P41544", "YJL004C", "species_29438" ] }, "reaction_10785206": { "compartment": "compartment_263163", "id": "reaction_10785206", "reactome": "R-SCE-6814091", "name": "ARL1 recruits TGN Golgin homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785202", "species_10785187" ], "products": [ "species_10785204" ], "modifiers": [], "additional_components": [ "P47166", "YJR134C", "Q02804", "ARL3", "P38116", "YBR164C", "P41544", "YJL004C", "species_29438", "Q02804", "ARL3", "P38116", "YBR164C", "P47166", "YJR134C", "P41544", "YJL004C", "species_29438" ] }, "reaction_10785104": { "compartment": "compartment_263163", "id": "reaction_10785104", "reactome": "R-SCE-6811428", "name": "RIC1:RGP1 recruits RAB6:GDP to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785096", "species_10785084" ], "products": [ "species_10785102" ], "modifiers": [], "additional_components": [ "P16664", "YDR137W", "P40395", "YLR039C", "species_29420", "Q99260", "YLR262C", "species_29420", "P16664", "YDR137W", "Q99260", "YLR262C", "P40395", "YLR039C" ] }, "reaction_10785314": { "compartment": "compartment_263163", "id": "reaction_10785314", "reactome": "R-SCE-6814684", "name": "cis-SNARE binds SNAPs and NSF hexamer at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10785310" ], "products": [ "species_10785312" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "P31377", "YAL014C", "Q03322", "YDR468C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P31377", "YAL014C", "Q03322", "YDR468C", "P18759", "YBR080C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P32602", "YBL050W" ] }, "reaction_10785111": { "compartment": "compartment_263163", "id": "reaction_10785111", "reactome": "R-SCE-6811429", "name": "RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10785102" ], "products": [ "species_10785108", "species_29420" ], "modifiers": [ [ "species_10785102", "catalyst" ] ], "additional_components": [ "species_29420", "P16664", "YDR137W", "Q99260", "YLR262C", "P40395", "YLR039C", "P16664", "YDR137W", "Q99260", "YLR262C", "species_29438", "P40395", "YLR039C", "species_29420", "P16664", "YDR137W", "Q99260", "YLR262C", "P40395", "YLR039C" ] }, "reaction_10785189": { "compartment": "compartment_263163", "id": "reaction_10785189", "reactome": "R-SCE-6814086", "name": "ARFRP1 recruits ARL1 to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785173", "species_10785181" ], "products": [ "species_10785187" ], "modifiers": [], "additional_components": [ "Q02804", "ARL3", "P41544", "YJL004C", "species_29438", "P38116", "YBR164C", "species_29438", "Q02804", "ARL3", "P38116", "YBR164C", "P41544", "YJL004C", "species_29438" ] }, "reaction_10785258": { "compartment": "compartment_263163", "id": "reaction_10785258", "reactome": "R-SCE-6814678", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10785253" ], "products": [ "species_29370", "species_10785249", "species_10785245", "species_10769994", "species_10781444", "species_10785247", "species_10785240" ], "modifiers": [ [ "species_10785253", "catalyst" ] ], "additional_components": [ "Q03322", "YDR468C", "P33328", "YOR327C", "P18759", "YBR080C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P32602", "YBL050W", "YOR327C", "YOL018C", "YBL050W", "P18759", "YBR080C", "YMR197C", "YDR468C", "Q03322", "YDR468C", "P33328", "YOR327C", "P18759", "YBR080C", "Q04338", "YMR197C", "Q08144", "YOL018C", "P32602", "YBL050W" ] }, "reaction_10768386": { "compartment": "compartment_70101", "id": "reaction_10768386", "reactome": "R-SCE-350769", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10768358" ], "products": [ "species_10768366", "species_29420" ], "modifiers": [ [ "species_10768383", "catalyst" ] ], "additional_components": [ "species_29420", "P11076", "YDL192W", "P19146", "YDL137W", "P11076", "YDL192W", "P19146", "YDL137W", "species_29438", "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C" ] }, "reaction_10768579": { "compartment": "compartment_70101", "id": "reaction_10768579", "reactome": "R-SCE-376357", "name": "Vamp7 associated Lysosome to Plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768561", "species_10768567", "species_10768572" ], "products": [ "species_10768561", "species_10768567", "species_10768574" ], "modifiers": [ [ "species_10768576", "catalyst" ] ], "additional_components": [ "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "YLR093C", "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "YLR093C", "P40357", "YGR009C", "Q12255", "YLR093C", "P32867", "YPL232W", "Q04359", "YMR017W", "P39926", "YMR183C" ] }, "reaction_10768619": { "compartment": "compartment_876", "id": "reaction_10768619", "reactome": "R-SCE-376369", "name": "Vamp2 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768561", "species_10768567", "species_10768608" ], "products": [ "species_10768561", "species_10768567", "species_10768614" ], "modifiers": [ [ "species_10768616", "catalyst" ] ], "additional_components": [ "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "P33328", "YOR327C", "P31109", "YAL030W", "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "P33328", "YOR327C", "P31109", "YAL030W", "P40357", "YGR009C", "P32867", "YPL232W", "P33328", "YOR327C", "Q04359", "YMR017W", "P31109", "YAL030W", "P39926", "YMR183C" ] }, "reaction_10768602": { "compartment": "compartment_70101", "id": "reaction_10768602", "reactome": "R-SCE-376364", "name": "Vamp8 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768591", "species_10768561", "species_10768567" ], "products": [ "species_10768561", "species_10768597", "species_10768567" ], "modifiers": [ [ "species_10768599", "catalyst" ] ], "additional_components": [ "P33328", "YOR327C", "P31109", "YAL030W", "P40357", "YGR009C", "Q04359", "YMR017W", "P32867", "YPL232W", "P39926", "YMR183C", "P40357", "YGR009C", "Q04359", "YMR017W", "P33328", "YOR327C", "P31109", "YAL030W", "P32867", "YPL232W", "P39926", "YMR183C", "P40357", "YGR009C", "P32867", "YPL232W", "P33328", "YOR327C", "Q04359", "YMR017W", "P31109", "YAL030W", "P39926", "YMR183C" ] }, "reaction_10776489": { "compartment": "compartment_7660", "id": "reaction_10776489", "reactome": "R-SCE-4411373", "name": "NLK translocates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776483" ], "products": [ "species_10776487" ], "modifiers": [], "additional_components": [ "P41808", "YPR054W", "P41808", "YPR054W" ] }, "reaction_10776538": { "compartment": "compartment_70101", "id": "reaction_10776538", "reactome": "R-SCE-4551465", "name": "Translocation of NFATC1:CaN:CaM to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10776532" ], "products": [ "species_10776536" ], "modifiers": [], "additional_components": [ "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C", "P06787", "YBR109C", "species_158417", "species_74016", "P14747", "YML057W", "P25296", "YKL190W", "CHEBI:29034", "P23287", "YLR433C" ] }, "reaction_10771589": { "compartment": "compartment_70101", "id": "reaction_10771589", "reactome": "R-SCE-917700", "name": "MVB Vesicle Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771585", "species_10771366" ], "products": [ "species_10771444", "species_10771583" ], "modifiers": [], "additional_components": [ "Q06696", "YLR417W", "Q12483", "YPL002C", "P05759", "RPS31", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P47142", "YJR102C", "P36095", "YKL041W", "P39929", "YLR025W", "Q03390", "YDR486C", "P36108", "YKL002W", "Q04272", "YMR077C", "P36095", "YKL041W", "P05759", "RPS31", "P39929", "YLR025W", "Q03390", "YDR486C", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P36108", "YKL002W", "Q04272", "YMR077C", "Q06696", "YLR417W", "Q12483", "YPL002C", "P47142", "YJR102C" ] }, "reaction_10771539": { "compartment": "compartment_74700", "id": "reaction_10771539", "reactome": "R-SCE-917693", "name": "ESCRT Disassembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10771444" ], "products": [ "species_10771364", "species_29370", "species_10771520", "species_10771359", "species_10771350", "species_29372", "species_10771345", "species_10771340" ], "modifiers": [ [ "species_10771536", "catalyst" ] ], "additional_components": [ "P36095", "YKL041W", "P05759", "RPS31", "P39929", "YLR025W", "Q03390", "YDR486C", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P36108", "YKL002W", "Q04272", "YMR077C", "YDR486C", "P05759", "RPS31", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "YMR077C", "YLR025W", "YKL041W", "YKL002W", "Q06263", "YLR181C", "Q03390", "YDR486C", "P52917", "YPR173C" ] }, "reaction_10771587": { "compartment": "compartment_70101", "id": "reaction_10771587", "reactome": "R-SCE-917696", "name": "Cargo Sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10771566", "species_10771583" ], "products": [ "species_10771585", "species_10771564" ], "modifiers": [], "additional_components": [ "Q02767", "YPL065W", "P05759", "RPS31", "Q99176", "YLR119W", "P25604", "YCL008C", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "Q06696", "YLR417W", "Q12483", "YPL002C", "P47142", "YJR102C", "Q06696", "YLR417W", "Q12483", "YPL002C", "P05759", "RPS31", "species_179838", "P0CH09", "RPL40B", "P0CH08", "RPL40A", "P47142", "YJR102C", "Q02767", "YPL065W", "Q99176", "YLR119W", "P25604", "YCL008C" ] }, "reaction_10772483": { "compartment": "compartment_70101", "id": "reaction_10772483", "reactome": "R-SCE-984606", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772463" ], "products": [ "species_10772465" ], "modifiers": [], "additional_components": [ "YEL061C", "P27895", "YEL061C" ] }, "reaction_10774270": { "compartment": "compartment_70101", "id": "reaction_10774270", "reactome": "R-SCE-2219524", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10767662", "species_179856" ], "products": [ "species_10774268" ], "modifiers": [], "additional_components": [ "YOL100W", "Q12236", "YOL100W", "species_179856" ] }, "reaction_10785347": { "compartment": "compartment_20699", "id": "reaction_10785347", "reactome": "R-SCE-8847637", "name": "NSF and SNAPs bind the cis-SNARE at the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10769994", "species_10781444", "species_10785343" ], "products": [ "species_10785345" ], "modifiers": [], "additional_components": [ "YBL050W", "P18759", "YBR080C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P43682", "YKL006C-A", "P38736", "YHL031C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W" ] }, "reaction_10785368": { "compartment": "compartment_20699", "id": "reaction_10785368", "reactome": "R-SCE-8847875", "name": "ARF1:GTP binds Golgin TRIP11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785364", "species_10773521" ], "products": [ "species_10785366" ], "modifiers": [], "additional_components": [ "Q12234", "YOR216C", "P11491", "YDR481C", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996", "Q12234", "YOR216C", "P11491", "YDR481C", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10785424": { "compartment": "compartment_20699", "id": "reaction_10785424", "reactome": "R-SCE-8847880", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785394", "species_10773521" ], "products": [ "species_10785422" ], "modifiers": [], "additional_components": [ "P47102", "YJR031C", "P39993", "YEL022W", "Q06836", "YPR095C", "P11076", "YDL192W", "P19146", "YDL137W", "CHEBI:15996", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "Q06836", "YPR095C", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10785431": { "compartment": "compartment_20699", "id": "reaction_10785431", "reactome": "R-SCE-8847883", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10785422" ], "products": [ "species_10785428" ], "modifiers": [ [ "species_10785422", "catalyst" ] ], "additional_components": [ "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "Q06836", "YPR095C", "P19146", "YDL137W", "CHEBI:15996", "species_29420", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "Q06836", "YPR095C", "P19146", "YDL137W", "P47102", "YJR031C", "P11076", "YDL192W", "P39993", "YEL022W", "Q06836", "YPR095C", "P19146", "YDL137W", "CHEBI:15996" ] }, "reaction_10785350": { "compartment": "compartment_20699", "id": "reaction_10785350", "reactome": "R-SCE-8847638", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10785345" ], "products": [ "species_10784697", "species_29370", "species_10784688", "species_10784699", "species_10769994", "species_10781444", "species_10784683" ], "modifiers": [ [ "species_10785345", "catalyst" ] ], "additional_components": [ "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W", "P22804", "YIL004C", "P43682", "YKL006C-A", "YHL031C", "YLR026C", "YBL050W", "P18759", "YBR080C", "YKL196C", "Q01590", "YLR026C", "P22804", "YIL004C", "P36015", "YKL196C", "P18759", "YBR080C", "P43682", "YKL006C-A", "P38736", "YHL031C", "P32602", "YBL050W" ] }, "reaction_10772494": { "compartment": "compartment_17906", "id": "reaction_10772494", "reactome": "R-SCE-992703", "name": "Mitofusins trans-interact linking mitochondria prior to fusion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772488" ], "products": [ "species_10772492" ], "modifiers": [], "additional_components": [ "YBR179C", "P38297", "YBR179C" ] }, "reaction_10772555": { "compartment": "compartment_74700", "id": "reaction_10772555", "reactome": "R-SCE-1011576", "name": "EHD proteins interact with Rabenosyn-5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10772546", "species_10772551" ], "products": [ "species_10772553" ], "modifiers": [], "additional_components": [ "P32790", "YBL007C", "P36115", "YKR019C", "YDR323C", "P32790", "YBL007C", "P36115", "YKR019C", "P32609", "YDR323C" ] }, "reaction_10772520": { "compartment": "compartment_5460", "id": "reaction_10772520", "reactome": "R-SCE-1008248", "name": "Adenylate Kinase 3 is a GTP-AMP phosphotransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159448", "species_113573" ], "products": [ "species_113525", "species_113581" ], "modifiers": [ [ "species_10772517", "catalyst" ] ], "additional_components": [ "YER170W" ] }, "reaction_10772572": { "compartment": "compartment_70101", "id": "reaction_10772572", "reactome": "R-SCE-1011598", "name": "DOCKs bind to RhoGEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10768888", "species_10772560" ], "products": [ "species_10772570" ], "modifiers": [], "additional_components": [ "YLR229C", "YLR422W", "Q06409", "YLR422W", "P19073", "YLR229C" ] }, "reaction_10772503": { "compartment": "compartment_70101", "id": "reaction_10772503", "reactome": "R-SCE-992708", "name": "Dual-specific AKAPs bind type I and II PKA regulatory subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. 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